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ONTOLOGY REPORT - ANNOTATIONS


Term:melphalan
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Accession:CHEBI:28876 term browser browse the term
Definition:A phenylalanine derivative comprising L-phenylalanine having [bis(2-chloroethyl)amino group at the 4-position on the phenyl ring.
Synonyms:related_synonym: 3-p-(Di(2-chloroethyl)amino)-phenyl-L-alanine;   4-(Bis(2-chloroethyl)amino)-L-phenylalanine;   Formula=C13H18Cl2N2O2;   InChI=1S/C13H18Cl2N2O2/c14-5-7-17(8-6-15)11-3-1-10(2-4-11)9-12(16)13(18)19/h1-4,12H,5-9,16H2,(H,18,19)/t12-/m0/s1;   InChIKey=SGDBTWWWUNNDEQ-LBPRGKRZSA-N;   L-3-(p-(Bis(2-chloroethyl)amino)phenyl)alanine;   L-PAM;   L-Phenylalanine mustard;   L-Sarcolysine;   Phenylalanine mustard;   Phenylalanine nitrogen mustard;   SMILES=N[C@@H](Cc1ccc(cc1)N(CCCl)CCCl)C(O)=O;   melfalano;   melphalanum;   p-Bis(beta-chloroethyl)aminophenylalanine;   p-Di-(2-chloroethyl)amino-L-phenylalanine;   p-L-Sarcolysin;   p-N,N-bis(2-chloroethyl)amino-L-phenylalanine;   p-N-Bis(2-chloroethyl)amino-L-phenylalanine
 alt_id: CHEBI:25815;   CHEBI:6742
 xref: CAS:148-82-3 "ChemIDplus";   CAS:148-82-3 "KEGG DRUG";   DrugBank:DB01042;   Drug_Central:1678 "DrugCentral";   KEGG:D00369
 xref_mesh: MESH:D008558
 xref: PMID:10820424 "Europe PMC";   PMID:10937717 "Europe PMC";   PMID:11680815 "Europe PMC";   PMID:11914777 "Europe PMC";   PMID:18481314 "Europe PMC";   PMID:445303 "Europe PMC";   PMID:7494795 "Europe PMC";   PMID:7605343 "Europe PMC";   PMID:8552138 "Europe PMC";   PMID:8951232 "Europe PMC";   PMID:9218926 "Europe PMC";   PMID:9250538 "Europe PMC";   Patent:US108552;   Patent:US275057;   Patent:US3032584;   Patent:US3032585;   Reaxys:2816456 "Reaxys";   Wikipedia:Melphalan


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melphalan term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcc1 ATP binding cassette subfamily C member 1 JBrowse link 10 549,537 672,235 RGD:6480464
G Abhd17c abhydrolase domain containing 17C JBrowse link 1 146,248,505 146,289,465 RGD:6480464
G Abraxas1 abraxas 1, BRCA1 A complex subunit JBrowse link 14 10,424,674 10,439,010 RGD:6480464
G Abt1 activator of basal transcription 1 JBrowse link 17 43,946,118 43,948,224 RGD:6480464
G Ackr3 atypical chemokine receptor 3 JBrowse link 9 97,355,881 97,367,455 RGD:6480464
G Acvr1c activin A receptor type 1C JBrowse link 3 44,272,859 44,342,501 RGD:6480464
G Ahrr aryl-hydrocarbon receptor repressor JBrowse link 1 31,603,297 31,698,329 RGD:6480464
G Alad aminolevulinate dehydratase JBrowse link 5 78,368,867 78,379,206 RGD:6480464
G Ammecr1l AMMECR1 like JBrowse link 18 24,539,530 24,563,576 RGD:6480464
G Ankar ankyrin and armadillo repeat containing JBrowse link 9 53,011,561 53,086,178 RGD:6480464
G Ankrd10 ankyrin repeat domain 10 JBrowse link 16 83,205,898 83,229,147 RGD:6480464
G Ankrd28 ankyrin repeat domain 28 JBrowse link 16 7,816,876 7,879,023 RGD:6480464
G Ankrd34a ankyrin repeat domain 34A JBrowse link 2 198,720,277 198,725,155 RGD:6480464
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:6480464
G Arhgap12 Rho GTPase activating protein 12 JBrowse link 17 54,280,815 54,394,716 RGD:6480464
G Arhgap18 Rho GTPase activating protein 18 JBrowse link 1 19,227,115 19,463,139 RGD:6480464
G Arhgap20 Rho GTPase activating protein 20 JBrowse link 8 56,179,581 56,264,343 RGD:6480464
G Arhgap24 Rho GTPase activating protein 24 JBrowse link 14 8,383,211 8,600,526 RGD:6480464
G Arhgap42 Rho GTPase activating protein 42 JBrowse link 8 7,210,999 7,446,215 RGD:6480464
G Arid5a AT-rich interaction domain 5A JBrowse link 9 42,871,907 42,886,725 RGD:6480464
G Atg16l1 autophagy related 16-like 1 JBrowse link 9 94,879,876 94,915,231 RGD:6480464
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 JBrowse link 7 41,114,606 41,223,138 RGD:6480464
G Aurka aurora kinase A JBrowse link 3 170,364,177 170,380,278 RGD:6480464
G Aurkb aurora kinase B JBrowse link 10 55,625,860 55,632,399 RGD:6480464
G B3gnt2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 JBrowse link 14 107,592,336 107,617,189 RGD:6480464
G B3gnt5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 JBrowse link 11 84,919,055 84,931,160 RGD:6480464
G Bak1 BCL2-antagonist/killer 1 JBrowse link 20 5,609,620 5,618,899 RGD:6480464
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:6480464
G Bche butyrylcholinesterase JBrowse link 2 171,104,476 171,196,186 RGD:6480464
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:6480464
G Bcl2a1 BCL2-related protein A1 JBrowse link 8 96,551,424 96,559,527 RGD:6480464
G Bicc1 BicC family RNA binding protein 1 JBrowse link 20 18,780,605 18,940,429 RGD:6480464
G Bicdl2 BICD family like cargo adaptor 2 JBrowse link 10 12,980,696 12,989,133 RGD:6480464
G Birc5 baculoviral IAP repeat-containing 5 JBrowse link 10 106,856,097 106,864,419 RGD:6480464
G Bnc2 basonuclin 2 JBrowse link 5 102,407,508 102,807,389 RGD:6480464
G Btg2 BTG anti-proliferation factor 2 JBrowse link 13 50,913,185 50,916,944 RGD:6480464
G Cables1 Cdk5 and Abl enzyme substrate 1 JBrowse link 18 3,317,724 3,421,721 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Casp9 caspase 9 JBrowse link 5 160,356,211 160,373,774 RGD:6480464
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:6480464
G Cc2d2a coiled-coil and C2 domain containing 2A JBrowse link 14 71,895,128 71,979,452 RGD:6480464
G Ccdc110 coiled-coil domain containing 110 JBrowse link 16 49,509,885 49,522,094 RGD:6480464
G Ccdc171 coiled-coil domain containing 171 JBrowse link 5 101,639,355 102,017,300 RGD:6480464
G Ccl20 C-C motif chemokine ligand 20 JBrowse link 9 88,918,359 88,921,017 RGD:6480464
G Ccnj cyclin J JBrowse link 1 259,926,537 259,944,275 RGD:6480464
G Cd34 CD34 molecule JBrowse link 13 113,691,842 113,711,259 RGD:6480464
G Cd59 CD59 molecule JBrowse link 3 94,010,481 94,028,660 RGD:6480464
G Cda cytidine deaminase JBrowse link 5 156,703,579 156,734,541 RGD:6480464
G Cdc14b cell division cycle 14B JBrowse link 17 1,709,703 1,797,732 RGD:6480464
G Cdc42ep3 CDC42 effector protein 3 JBrowse link 6 1,922,500 1,942,972 RGD:6480464
G Cfap206 cilia and flagella associated protein 206 JBrowse link 5 50,148,685 50,193,580 RGD:6480464
G Chek1 checkpoint kinase 1 JBrowse link 8 39,181,162 39,201,588 RGD:6480464
G Chek2 checkpoint kinase 2 JBrowse link 12 51,845,574 51,878,098 RGD:6480464
G Chuk component of inhibitor of nuclear factor kappa B kinase complex JBrowse link 1 263,848,829 263,884,354 RGD:6480464
G Ciita class II, major histocompatibility complex, transactivator JBrowse link 10 5,212,621 5,260,641 RGD:6480464
G Cited4 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4 JBrowse link 5 139,597,731 139,598,622 RGD:6480464
G Cnksr3 Cnksr family member 3 JBrowse link 1 43,789,797 43,884,267 RGD:6480464
G Cpne8 copine 8 JBrowse link 7 131,623,180 131,798,236 RGD:6480464
G Creb5 cAMP responsive element binding protein 5 JBrowse link 4 83,390,782 83,840,356 RGD:6480464
G Cul3 cullin 3 JBrowse link 9 86,044,485 86,129,066 RGD:6480464
G Cxcl12 C-X-C motif chemokine ligand 12 JBrowse link 4 149,261,044 149,273,891 RGD:6480464
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:6480464
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 8 62,451,360 62,458,244 RGD:6480464
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 JBrowse link 7 70,333,150 70,340,006 RGD:6480464
G Dbf4 DBF4 zinc finger JBrowse link 4 22,898,527 22,914,091 RGD:6480464
G Dcn decorin JBrowse link 7 38,742,250 38,782,282 RGD:6480464
G Dennd4c DENN domain containing 4C JBrowse link 5 105,100,081 105,195,634 RGD:6480464
G Dlg3 discs large MAGUK scaffold protein 3 JBrowse link X 70,596,246 70,648,529 RGD:6480464
G Dst dystonin JBrowse link 9 37,902,336 38,296,961 RGD:6480464
G Dusp2 dual specificity phosphatase 2 JBrowse link 3 119,776,925 119,779,110 RGD:6480464
G Eaf1 ELL associated factor 1 JBrowse link 16 7,588,217 7,602,966 RGD:6480464
G Ebf1 EBF transcription factor 1 JBrowse link 10 23,654,849 24,051,627 RGD:6480464
G Edn1 endothelin 1 JBrowse link 17 22,136,814 22,143,745 RGD:6480464
G Eepd1 endonuclease/exonuclease/phosphatase family domain containing 1 JBrowse link 8 26,651,241 26,758,330 RGD:6480464
G Efna2 ephrin A2 JBrowse link 7 12,382,636 12,393,266 RGD:6480464
G Efna5 ephrin A5 JBrowse link 9 110,054,002 110,329,878 RGD:6480464
G Emx2 empty spiracles homeobox 2 JBrowse link 1 280,633,938 280,640,946 RGD:6480464
G Enox1 ecto-NOX disulfide-thiol exchanger 1 JBrowse link 15 59,331,134 59,884,512 RGD:6480464
G Epha5 EPH receptor A5 JBrowse link 14 25,589,312 25,958,258 RGD:6480464
G Exoc6 exocyst complex component 6 JBrowse link 1 256,211,879 256,369,318 RGD:6480464
G Fabp5 fatty acid binding protein 5 JBrowse link 2 93,981,662 93,985,322 RGD:6480464
G Fam110b family with sequence similarity 110, member B JBrowse link 5 18,762,488 18,903,818 RGD:6480464
G Fam49a family with sequence similarity 49, member A JBrowse link 6 37,555,167 37,661,196 RGD:6480464
G Fam90a1 family with sequence similarity 90, member A1 JBrowse link 16 75,001,033 75,016,173 RGD:6480464
G Fancc FA complementation group C JBrowse link 17 826,512 955,703 RGD:6480464
G Fancg FA complementation group G JBrowse link 5 58,448,060 58,456,416 RGD:6480464
G Fat4 FAT atypical cadherin 4 JBrowse link 2 125,751,818 125,879,398 RGD:6480464
G Fgd4 FYVE, RhoGEF and PH domain containing 4 JBrowse link 11 88,699,222 88,796,677 RGD:6480464
G Fgd6 FYVE, RhoGEF and PH domain containing 6 JBrowse link 7 34,951,878 35,063,006 RGD:6480464
G Fgf5 fibroblast growth factor 5 JBrowse link 14 12,974,921 12,996,046 RGD:6480464
G Fign fidgetin, microtubule severing factor JBrowse link 3 49,992,250 50,120,601 RGD:6480464
G Fmn2 formin 2 JBrowse link 13 92,569,256 92,887,302 RGD:6480464
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit JBrowse link 1 80,214,691 80,221,417 RGD:6480464
G Foxp2 forkhead box P2 JBrowse link 4 41,364,441 41,944,685 RGD:6480464
G Frmd4a FERM domain containing 4A JBrowse link 17 77,642,302 77,918,210 RGD:6480464
G Frmd4b FERM domain containing 4B JBrowse link 4 129,658,137 129,984,735 RGD:6480464
G Fry FRY microtubule binding protein JBrowse link 12 5,573,729 5,822,874 RGD:6480464
G Fut10 fucosyltransferase 10 JBrowse link 16 64,623,246 64,716,248 RGD:6480464
G Gab1 GRB2-associated binding protein 1 JBrowse link 19 30,794,290 30,903,819 RGD:6480464
G Garem1 GRB2 associated regulator of MAPK1 subtype 1 JBrowse link 18 14,982,604 15,007,245 RGD:6480464
G Gas1 growth arrest-specific 1 JBrowse link 17 4,846,116 4,849,350 RGD:6480464
G Gcnt1 glucosaminyl (N-acetyl) transferase 1 JBrowse link 1 236,547,729 236,585,037 RGD:6480464
G Gli3 GLI family zinc finger 3 JBrowse link 17 52,294,942 52,569,036 RGD:6480464
G Grin2c glutamate ionotropic receptor NMDA type subunit 2C JBrowse link 10 103,798,290 103,816,923 RGD:6480464
G Grk5 G protein-coupled receptor kinase 5 JBrowse link 1 282,265,371 282,467,842 RGD:6480464
G Gsta3 glutathione S-transferase alpha 3 JBrowse link 9 27,357,490 27,417,023 RGD:6480464
G Gsta5 glutathione S-transferase alpha 5 JBrowse link 8 85,553,659 85,564,914 RGD:6480464
G Gstm1 glutathione S-transferase mu 1 JBrowse link 2 210,803,869 210,809,461 RGD:6480464
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:6480464
G Hecw2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 JBrowse link 9 60,451,476 60,843,160 RGD:6480464
G Hgf hepatocyte growth factor JBrowse link 4 15,435,460 15,505,377 RGD:6480464
G Hmga2 high mobility group AT-hook 2 JBrowse link 7 65,159,944 65,275,408 RGD:6480464
G Hoxd1 homeo box D1 JBrowse link 3 61,685,619 61,687,758 RGD:6480464
G Icam1 intercellular adhesion molecule 1 JBrowse link 8 22,035,287 22,047,049 RGD:6480464
G Ier3 immediate early response 3 JBrowse link 20 3,438,798 3,440,002 RGD:6480464
G Ikbke inhibitor of nuclear factor kappa B kinase subunit epsilon JBrowse link 13 48,031,325 48,056,394 RGD:6480464
G Ikzf2 IKAROS family zinc finger 2 JBrowse link 9 76,621,230 76,771,017 RGD:6480464
G Il12a interleukin 12A JBrowse link 2 165,076,945 165,083,996 RGD:6480464
G Il16 interleukin 16 JBrowse link 1 145,781,923 145,881,538 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Il23a interleukin 23 subunit alpha JBrowse link 7 2,710,609 2,712,723 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Il7 interleukin 7 JBrowse link 2 96,427,884 96,474,979 RGD:6480464
G Irf2 interferon regulatory factor 2 JBrowse link 16 48,582,354 48,732,129 RGD:6480464
G Jade2 jade family PHD finger 2 JBrowse link 10 37,269,132 37,315,638 RGD:6480464
G Jak2 Janus kinase 2 JBrowse link 1 247,398,667 247,457,521 RGD:6480464
G Jakmip3 janus kinase and microtubule interacting protein 3 JBrowse link 1 211,292,604 211,421,023 RGD:6480464
G Kalrn kalirin, RhoGEF kinase JBrowse link 11 69,484,293 70,025,682 RGD:6480464
G Kbtbd3 kelch repeat and BTB domain containing 3 JBrowse link 8 1,450,345 1,477,250 RGD:6480464
G Kitlg KIT ligand JBrowse link 7 42,269,784 42,351,054 RGD:6480464
G Klf12 Kruppel-like factor 12 JBrowse link 15 84,316,986 84,748,549 RGD:6480464
G Klhl42 kelch-like family, member 42 JBrowse link 4 181,481,147 181,502,916 RGD:6480464
G Lrig3 leucine-rich repeats and immunoglobulin-like domains 3 JBrowse link 7 69,213,098 69,263,251 RGD:6480464
G Lurap1 leucine rich adaptor protein 1 JBrowse link 5 134,991,997 135,001,720 RGD:6480464
G Lyst lysosomal trafficking regulator JBrowse link 17 90,323,055 90,522,091 RGD:6480464
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6480464
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6480464
G Mboat1 membrane bound O-acyltransferase domain containing 1 JBrowse link 17 36,061,775 36,177,457 RGD:6480464
G Meox2 mesenchyme homeobox 2 JBrowse link 6 56,625,768 56,689,195 RGD:6480464
G Mex3a mex-3 RNA binding family member A JBrowse link 2 187,893,678 187,902,546 RGD:6480464
G Mex3b mex-3 RNA binding family member B JBrowse link 1 144,831,523 144,835,758 RGD:6480464
G Mfsd2a major facilitator superfamily domain containing 2A JBrowse link 5 140,642,865 140,657,759 RGD:6480464
G Mgst2 microsomal glutathione S-transferase 2 JBrowse link 2 140,708,396 140,727,381 RGD:6480464
G Mitf melanocyte inducing transcription factor JBrowse link 4 130,172,484 130,425,496 RGD:6480464
G Mllt3 MLLT3, super elongation complex subunit JBrowse link 5 106,103,498 106,202,559 RGD:6480464
G Mms22l MMS22-like, DNA repair protein JBrowse link 5 38,844,502 38,960,989 RGD:6480464
G Mrtfb myocardin related transcription factor B JBrowse link 10 1,151,163 1,273,269 RGD:6480464
G Mta3 metastasis associated 1 family, member 3 JBrowse link 6 6,904,449 7,036,929 RGD:6480464
G Mtcl1 microtubule crosslinking factor 1 JBrowse link 9 114,493,901 114,632,632 RGD:6480464
G Myo1b myosin Ib JBrowse link 9 54,706,005 54,766,054 RGD:6480464
G Nebl nebulette JBrowse link 17 84,141,014 84,247,038 RGD:6480464
G Nfia nuclear factor I/A JBrowse link 5 116,421,895 116,750,381 RGD:6480464
G Nhs NHS actin remodeling regulator JBrowse link X 34,312,102 34,675,912 RGD:6480464
G Nkrf NFKB repressing factor JBrowse link X 123,502,074 123,516,301 RGD:6480464
G Nop56 NOP56 ribonucleoprotein JBrowse link 3 122,803,726 122,808,564 RGD:6480464
G Nppb natriuretic peptide B JBrowse link 5 164,796,176 164,797,538 RGD:6480464
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 JBrowse link 5 63,781,801 63,822,890 RGD:6480464
G Nrg2 neuregulin 2 JBrowse link 18 28,835,391 29,015,552 RGD:6480464
G Nrp1 neuropilin 1 JBrowse link 19 61,332,351 61,486,166 RGD:6480464
G Nuak1 NUAK family kinase 1 JBrowse link 7 25,039,336 25,111,118 RGD:6480464
G Osbpl10 oxysterol binding protein-like 10 JBrowse link 8 123,029,722 123,303,553 RGD:6480464
G Pag1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 JBrowse link 2 94,266,104 94,277,680 RGD:6480464
G Pdlim5 PDZ and LIM domain 5 JBrowse link 2 247,815,214 247,989,198 RGD:6480464
G Phf21a PHD finger protein 21A JBrowse link 3 81,099,765 81,271,841 RGD:6480464
G Phf3 PHD finger protein 3 JBrowse link 9 37,073,514 37,144,027 RGD:6480464
G Phlda1 pleckstrin homology-like domain, family A, member 1 JBrowse link 7 54,247,460 54,249,664 RGD:6480464
G Phldb2 pleckstrin homology-like domain, family B, member 2 JBrowse link 11 60,042,879 60,051,229 RGD:6480464
G Piga phosphatidylinositol glycan anchor biosynthesis, class A JBrowse link X 31,786,823 31,799,751 RGD:6480464
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 JBrowse link 2 31,742,326 31,826,882 RGD:6480464
G Pik3r3 phosphoinositide-3-kinase regulatory subunit 3 JBrowse link 5 135,069,972 135,145,633 RGD:6480464
G Plcl2 phospholipase C-like 2 JBrowse link 9 1,782,536 1,984,654 RGD:6480464
G Plekha2 pleckstrin homology domain containing A2 JBrowse link 16 71,725,649 71,784,432 RGD:6480464
G Plekha5 pleckstrin homology domain containing A5 JBrowse link 4 174,605,462 174,774,692 RGD:6480464
G Plk3 polo-like kinase 3 JBrowse link 5 135,997,725 136,002,900 RGD:6480464
G Ppif peptidylprolyl isomerase F JBrowse link 16 1,979,191 1,985,912 RGD:6480464
G Ppm1h protein phosphatase, Mg2+/Mn2+ dependent, 1H JBrowse link 7 66,845,692 67,116,979 RGD:6480464
G Ppp2r2b protein phosphatase 2, regulatory subunit B, beta JBrowse link 18 36,985,709 37,421,383 RGD:6480464
G Ppp2r5a protein phosphatase 2, regulatory subunit B', alpha JBrowse link 13 110,033,550 110,077,946 RGD:6480464
G Prune2 prune homolog 2 with BCH domain JBrowse link 1 236,676,963 236,947,527 RGD:6480464
G Psd3 pleckstrin and Sec7 domain containing 3 JBrowse link 16 23,212,165 23,789,414 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:6480464
G Ptprg protein tyrosine phosphatase, receptor type, G JBrowse link 15 12,926,056 13,633,839 RGD:6480464
G Pxk PX domain containing serine/threonine kinase JBrowse link 15 18,548,209 18,616,617 RGD:6480464
G Rad54b RAD54 homolog B JBrowse link 5 25,140,531 25,214,469 RGD:6480464
G Radx RPA1 related single stranded DNA binding protein, X-linked JBrowse link X 110,670,037 110,782,420 RGD:6480464
G Rarb retinoic acid receptor, beta JBrowse link 15 9,915,223 10,262,599 RGD:6480464
G Rasd1 ras related dexamethasone induced 1 JBrowse link 10 46,330,361 46,339,326 RGD:6480464
G Rasl10a RAS-like, family 10, member A JBrowse link 14 85,311,833 85,313,211 RGD:6480464
G Rasl11b RAS-like family 11 member B JBrowse link 14 36,550,353 36,554,574 RGD:6480464
G Rbm24 RNA binding motif protein 24 JBrowse link 17 18,671,037 18,682,876 RGD:6480464
G Rev3l REV3 like, DNA directed polymerase zeta catalytic subunit JBrowse link 20 44,803,664 44,961,362 RGD:6480464
G Rgl1 ral guanine nucleotide dissociation stimulator,-like 1 JBrowse link 13 69,909,122 70,174,590 RGD:6480464
G Rgmb repulsive guidance molecule BMP co-receptor b JBrowse link 1 57,794,046 57,819,941 RGD:6480464
G Rgs16 regulator of G-protein signaling 16 JBrowse link 13 71,163,411 71,185,147 RGD:6480464
G Rgs2 regulator of G-protein signaling 2 JBrowse link 13 60,846,458 60,849,061 RGD:6480464
G Ripor2 RHO family interacting cell polarization regulator 2 JBrowse link 17 42,324,594 42,549,907 RGD:6480464
G Rnf128 ring finger protein 128 JBrowse link X 110,789,061 110,877,964 RGD:6480464
G Rnf144b ring finger protein 144B JBrowse link 17 17,817,122 17,947,777 RGD:6480464
G Ror1 receptor tyrosine kinase-like orphan receptor 1 JBrowse link 5 118,892,874 119,239,528 RGD:6480464
G Rpl27a ribosomal protein L27a JBrowse link 1 174,132,798 174,135,816 RGD:6480464
G Rrad RRAD, Ras related glycolysis inhibitor and calcium channel regulator JBrowse link 19 561,696 564,929 RGD:6480464
G Rspo2 R-spondin 2 JBrowse link 7 81,919,911 82,059,659 RGD:6480464
G Runx1t1 RUNX1 partner transcriptional co-repressor 1 JBrowse link 5 27,284,921 27,440,802 RGD:6480464
G Scn8a sodium voltage-gated channel alpha subunit 8 JBrowse link 7 142,575,629 142,683,659 RGD:6480464
G Sema6d semaphorin 6D JBrowse link 3 116,899,906 116,958,059 RGD:6480464
G Serpinb2 serpin family B member 2 JBrowse link 13 27,449,907 27,463,015 RGD:6480464
G Sgk1 serum/glucocorticoid regulated kinase 1 JBrowse link 1 24,185,451 24,302,309 RGD:6480464
G Sgms1 sphingomyelin synthase 1 JBrowse link 1 250,692,448 250,951,685 RGD:6480464
G Shank2 SH3 and multiple ankyrin repeat domains 2 JBrowse link 1 217,149,156 217,593,950 RGD:6480464
G Shroom3 shroom family member 3 JBrowse link 14 16,622,767 16,903,265 RGD:6480464
G Sik1 salt-inducible kinase 1 JBrowse link 20 10,670,747 10,680,279 RGD:6480464
G Slc14a1 solute carrier family 14 member 1 (Kidd blood group) JBrowse link 18 74,461,064 74,504,475 RGD:6480464
G Slc19a2 solute carrier family 19 member 2 JBrowse link 13 82,552,586 82,566,586 RGD:6480464
G Smad2 SMAD family member 2 JBrowse link 18 72,550,107 72,612,078 RGD:6480464
G Smad3 SMAD family member 3 JBrowse link 8 68,569,530 68,678,349 RGD:6480464
G Sntb1 syntrophin, beta 1 JBrowse link 7 95,395,417 95,670,093 RGD:6480464
G Snx29 sorting nexin 29 JBrowse link 10 3,838,444 4,249,741 RGD:6480464
G Socs5 suppressor of cytokine signaling 5 JBrowse link 6 10,671,311 10,705,610 RGD:6480464
G Spata17 spermatogenesis associated 17 JBrowse link 13 105,489,121 105,684,293 RGD:6480464
G Spata7 spermatogenesis associated 7 JBrowse link 6 122,603,248 122,648,718 RGD:6480464
G Spred1 sprouty-related, EVH1 domain containing 1 JBrowse link 3 108,795,337 108,861,650 RGD:6480464
G Spty2d1 SPT2 chromatin protein domain containing 1 JBrowse link 1 103,115,280 103,129,438 RGD:6480464
G Srgap2 SLIT-ROBO Rho GTPase activating protein 2 JBrowse link 13 48,065,280 48,286,888 RGD:6480464
G Stac SH3 and cysteine rich domain JBrowse link 8 119,820,664 119,941,867 RGD:6480464
G Stambpl1 STAM binding protein-like 1 JBrowse link 1 252,490,125 252,536,113 RGD:6480464
G Tacc2 transforming, acidic coiled-coil containing protein 2 JBrowse link 1 201,140,264 201,329,612 RGD:6480464
G Tbc1d12 TBC1 domain family, member 12 JBrowse link 1 257,517,128 257,599,659 RGD:6480464
G Tbl1xr1 transducin (beta)-like 1 X-linked receptor 1 JBrowse link 2 107,221,913 107,359,229 RGD:6480464
G Tet1 tet methylcytosine dioxygenase 1 JBrowse link 20 27,359,122 27,438,039 RGD:6480464
G Tex30 testis expressed 30 JBrowse link 9 50,858,737 50,868,238 RGD:6480464
G Tfpi2 tissue factor pathway inhibitor 2 JBrowse link 4 28,947,951 28,953,261 RGD:6480464
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:6480464
G Thsd4 thrombospondin type 1 domain containing 4 JBrowse link 8 64,811,940 65,413,498 RGD:6480464
G Tigd2 tigger transposable element derived 2 JBrowse link 4 89,535,418 89,538,535 RGD:6480464
G Tlnrd1 talin rod domain containing 1 JBrowse link 1 146,027,821 146,029,840 RGD:6480464
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:6480464
G Tmem131l transmembrane 131 like JBrowse link 2 182,897,332 183,031,273 RGD:6480464
G Tmem200a transmembrane protein 200A JBrowse link 1 20,330,670 20,413,921 RGD:6480464
G Tmem26 transmembrane protein 26 JBrowse link 20 21,640,655 21,689,655 RGD:6480464
G Tmem88 transmembrane protein 88 JBrowse link 10 55,998,530 56,000,225 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Tnfrsf19 TNF receptor superfamily member 19 JBrowse link 15 41,249,820 41,316,203 RGD:6480464
G Tnni3 troponin I3, cardiac type JBrowse link 1 72,882,806 72,886,490 RGD:6480464
G Tnrc6b trinucleotide repeat containing adaptor 6B JBrowse link 7 121,930,610 122,147,934 RGD:6480464
G Tox thymocyte selection-associated high mobility group box JBrowse link 5 19,892,698 20,189,721 RGD:6480464
G Tp63 tumor protein p63 JBrowse link 11 78,234,853 78,456,559 RGD:6480464
G Trerf1 transcriptional regulating factor 1 JBrowse link 9 15,653,230 15,881,695 RGD:6480464
G Trib1 tribbles pseudokinase 1 JBrowse link 7 99,954,492 99,961,026 RGD:6480464
G Trmt10c tRNA methyltransferase 10C, mitochondrial RNase P subunit JBrowse link 11 47,047,342 47,052,420 RGD:6480464
G Ttc30b tetratricopeptide repeat domain 30B JBrowse link 3 62,758,754 62,761,325 RGD:6480464
G Tubg1 tubulin, gamma 1 JBrowse link 10 89,030,865 89,037,455 RGD:6480464
G Tuft1 tuftelin 1 JBrowse link 2 195,861,772 195,907,471 RGD:6480464
G Twnk twinkle mtDNA helicase JBrowse link 1 264,756,060 264,762,892 RGD:6480464
G Txnrd1 thioredoxin reductase 1 JBrowse link 7 26,946,124 26,984,400 RGD:6480464
G Ubap1l ubiquitin associated protein 1-like JBrowse link 8 70,876,516 70,895,723 RGD:6480464
G Usp36 ubiquitin specific peptidase 36 JBrowse link 10 107,292,828 107,324,355 RGD:6480464
G Usp53 ubiquitin specific peptidase 53 JBrowse link 2 227,098,795 227,160,385 RGD:6480464
G Utp25 UTP25, small subunit processor component JBrowse link 13 111,828,052 111,849,654 RGD:6480464
G Vdac1 voltage-dependent anion channel 1 JBrowse link 10 37,724,915 37,752,827 RGD:6480464
G Yod1 YOD1 deubiquitinase JBrowse link 13 47,441,296 47,443,013 RGD:6480464
G Ypel2 yippee-like 2 JBrowse link 10 74,241,032 74,298,691 RGD:6480464
G Yrdc yrdC N(6)-threonylcarbamoyltransferase domain containing JBrowse link 5 142,845,265 142,850,110 RGD:6480464
G Zbtb20 zinc finger and BTB domain containing 20 JBrowse link 11 62,014,925 62,561,113 RGD:6480464
G Zc3h12a zinc finger CCCH type containing 12A JBrowse link 5 143,111,342 143,120,131 RGD:6480464
G Zfhx4 zinc finger homeobox 4 JBrowse link 2 98,423,565 98,610,368 RGD:6480464
G Zfp277 zinc finger protein 277 JBrowse link 6 60,246,209 60,374,388 RGD:6480464
G Zfp438 zinc finger protein 438 JBrowse link 17 55,006,893 55,131,567 RGD:6480464
G Zfp521 zinc finger protein 521 JBrowse link 18 5,022,042 5,315,242 RGD:6480464
G Zfp618 zinc finger protein 618 JBrowse link 5 78,806,585 78,972,433 RGD:6480464
G Zswim5 zinc finger, SWIM-type containing 5 JBrowse link 5 135,735,825 135,854,525 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      biological role 19611
        immunomodulator 12650
          immunosuppressive agent 11918
            melphalan 270
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    main group molecular entity 19545
                      s-block molecular entity 19329
                        hydrogen molecular entity 19319
                          hydrides 18242
                            organic hydride 17528
                              organic fundamental parent 17528
                                hydrocarbon 16935
                                  cyclic hydrocarbon 15098
                                    monocyclic hydrocarbon 5631
                                      annulene 5447
                                        aromatic annulene 5447
                                          benzene 5447
                                            alkylbenzene 3187
                                              methylbenzene 3048
                                                toluene 2909
                                                  benzyl group 2351
                                                    phenylalanine 2351
                                                      L-phenylalanine 2096
                                                        L-phenylalanine derivative 2085
                                                          melphalan 270
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.