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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:beryllium atom
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Accession:CHEBI:30501 term browser browse the term
Definition:Alkaline earth metal atom with atomic number 4.
Synonyms:related_synonym: 4Be;   Be;   Formula=Be;   InChI=1S/Be;   InChIKey=ATBAMAFKBVZNFJ-UHFFFAOYSA-N;   SMILES=[Be];   berilio;   beryllium
 xref: CAS:7440-41-7;   Gmelin:16265
 xref_mesh: MESH:D001608
 xref: PMID:10858219;   PMID:11897645;   PMID:14643414;   PMID:16951350;   PMID:18250483;   PMID:18768897;   PMID:24912188;   Reaxys:14617151;   WebElements:Be


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beryllium atom term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn2a cyclin-dependent kinase inhibitor 2A multiple interactions EXP [Beryllium results in increased methylation of CDKN2A promoter] which results in decreased expression of CDKN2A mRNA CTD PMID:11872642 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Esr1 estrogen receptor 1 increases methylation EXP Beryllium results in increased methylation of ESR1 gene CTD PMID:11872642 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Hras HRas proto-oncogene, GTPase increases mutagenesis EXP Beryllium results in increased mutagenesis of HRAS gene CTD PMID:7545909 NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
JBrowse link
G Il1b interleukin 1 beta increases expression
affects expression
ISO Beryllium results in increased expression of IL1B mRNA
Beryllium affects the expression of IL1B mRNA
CTD PMID:8473757, PMID:8629860 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Tnf tumor necrosis factor increases response to substance
increases secretion
increases expression
ISO TNF promoter polymorphism results in increased susceptibility to Beryllium
Beryllium results in increased secretion of TNF protein
Beryllium results in increased expression of TNF mRNA
CTD PMID:8629860, PMID:12449171, PMID:15127972 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
beryllium dichloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 affects expression ISO beryllium chloride affects the expression of APEX1 mRNA CTD PMID:23793613 NCBI chr15:27,849,943...27,852,083
Ensembl chr15:27,849,979...27,852,082
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase affects expression ISO beryllium chloride affects the expression of OGG1 mRNA CTD PMID:23793613 NCBI chr 4:145,282,828...145,289,367
Ensembl chr 4:145,282,797...145,289,326
JBrowse link
G Tp53 tumor protein p53 increases expression ISO beryllium chloride results in increased expression of TRP53 mRNA CTD PMID:23793613 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
beryllium difluoride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO beryllium fluoride promotes the reaction [ABCB1 protein mutant form binds to 8-azidoadenosine 5'-triphosphate] CTD PMID:11027628 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 multiple interactions EXP beryllium fluoride promotes the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC6 protein]; Cobalt promotes the reaction [beryllium fluoride promotes the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC6 protein]]; Magnesium Chloride promotes the reaction [beryllium fluoride promotes the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC6 protein]]; Manganese promotes the reaction [beryllium fluoride promotes the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC6 protein]]; Nickel promotes the reaction [beryllium fluoride promotes the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC6 protein]] CTD PMID:12069597 NCBI chr 1:101,954,786...102,013,252
Ensembl chr 1:101,959,540...102,013,243
JBrowse link
G Abcc8 ATP binding cassette subfamily C member 8 decreases activity ISO
EXP
beryllium fluoride results in decreased activity of ABCC8 protein CTD PMID:17561960, PMID:18025464 NCBI chr 1:102,110,708...102,191,287
Ensembl chr 1:102,110,708...102,191,287
JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases expression ISO beryllium fluoride results in increased expression of CREB1 protein CTD PMID:11867686 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO beryllium fluoride results in increased expression of FOS protein CTD PMID:11867686 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 increases phosphorylation ISO beryllium fluoride results in increased phosphorylation of MAP2K1 protein CTD PMID:11867686 NCBI chr 8:69,134,218...69,722,573
Ensembl chr 8:69,134,223...69,164,758
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation ISO beryllium fluoride results in increased phosphorylation of MAPK3 protein CTD PMID:11867686 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression ISO beryllium fluoride results in increased expression of MYC protein CTD PMID:11867686 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
beryllium dihydride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn2a cyclin-dependent kinase inhibitor 2A multiple interactions EXP [Beryllium results in increased methylation of CDKN2A promoter] which results in decreased expression of CDKN2A mRNA CTD PMID:11872642 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Esr1 estrogen receptor 1 increases methylation EXP Beryllium results in increased methylation of ESR1 gene CTD PMID:11872642 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Hras HRas proto-oncogene, GTPase increases mutagenesis EXP Beryllium results in increased mutagenesis of HRAS gene CTD PMID:7545909 NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
JBrowse link
G Il1b interleukin 1 beta increases expression
affects expression
ISO Beryllium results in increased expression of IL1B mRNA
Beryllium affects the expression of IL1B mRNA
CTD PMID:8473757, PMID:8629860 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Tnf tumor necrosis factor increases expression
increases response to substance
increases secretion
ISO Beryllium results in increased expression of TNF mRNA
TNF promoter polymorphism results in increased susceptibility to Beryllium
Beryllium results in increased secretion of TNF protein
CTD PMID:8629860, PMID:12449171, PMID:15127972 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
beryllium sulfate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle increases expression ISO beryllium sulfate results in increased expression of ACTA2 mRNA CTD PMID:16314022 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Anxa5 annexin A5 increases expression ISO beryllium sulfate results in increased expression of ANXA5 mRNA CTD PMID:16314022 NCBI chr 2:123,162,477...123,194,730
Ensembl chr 2:123,162,461...123,193,130
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions
increases secretion
ISO beryllium sulfate promotes the reaction [RUNX1 protein binds to CCL3 promoter]
beryllium sulfate results in increased secretion of CCL3 mRNA
CTD PMID:16314022 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 increases secretion ISO beryllium sulfate results in increased secretion of CCL4 mRNA CTD PMID:16314022 NCBI chr10:70,870,926...70,886,357
Ensembl chr10:70,884,531...70,886,355
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression ISO beryllium sulfate results in increased expression of CCL5 mRNA CTD PMID:16314022 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Cd44 CD44 molecule (Indian blood group) increases expression ISO beryllium sulfate results in increased expression of CD44 mRNA CTD PMID:16314022 NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658
JBrowse link
G Cd86 CD86 molecule increases expression ISO beryllium sulfate results in increased expression of CD86 protein CTD PMID:19665512 NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression
ISO beryllium sulfate promotes the reaction [TP53 protein binds to CDKN1A promoter]
beryllium sulfate results in increased expression of CDKN1A mRNA; beryllium sulfate results in increased expression of CDKN1A protein
CTD PMID:17395767 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A increases expression ISO beryllium sulfate results in increased expression of CDKN2A mRNA; beryllium sulfate results in increased expression of CDKN2A protein CTD PMID:17395767 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO [beryllium sulfate co-treated with IFNG protein] results in increased expression of CREB1 protein CTD PMID:10755711 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Ctsl cathepsin L increases expression ISO beryllium sulfate results in increased expression of CTSL mRNA CTD PMID:16314022 NCBI chr17:1,873,105...1,879,266
Ensembl chr17:1,872,848...1,879,279
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 increases secretion ISO beryllium sulfate results in increased secretion of CXCL1 mRNA CTD PMID:16314022 NCBI chr14:18,743,678...18,745,457
Ensembl chr14:18,743,685...18,745,457
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 increases secretion ISO beryllium sulfate results in increased secretion of CXCL1 mRNA CTD PMID:16314022 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
JBrowse link
G Egr2 early growth response 2 increases expression ISO beryllium sulfate results in increased expression of EGR2 mRNA CTD PMID:16314022 NCBI chr20:22,452,170...22,461,018
Ensembl chr20:22,454,463...22,459,025
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
ISO beryllium sulfate results in increased expression of FOS mRNA
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [beryllium sulfate results in increased expression of FOS mRNA]; Dactinomycin inhibits the reaction [beryllium sulfate results in increased expression of FOS mRNA]; Ro 31-8220 inhibits the reaction [beryllium sulfate results in increased expression of FOS mRNA]
CTD PMID:11568973 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 increases expression ISO beryllium sulfate results in increased expression of HNRNPA1 mRNA CTD PMID:16314022 NCBI chr 7:144,865,302...144,871,592
Ensembl chr 7:144,865,608...144,871,585
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions
increases secretion
increases expression
ISO 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [beryllium sulfate results in increased expression of ICAM1 mRNA]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [beryllium sulfate results in increased secretion of ICAM1 protein]; Dimethyl Sulfoxide inhibits the reaction [beryllium sulfate results in increased secretion of ICAM1 protein]
beryllium sulfate results in increased expression of ICAM1 mRNA; beryllium sulfate results in increased expression of ICAM1 protein
CTD PMID:18539414 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Ifng interferon gamma increases expression
multiple interactions
ISO beryllium sulfate results in increased expression of IFNG protein
[beryllium sulfate co-treated with IFNG protein] results in increased expression of CREB1 protein; [beryllium sulfate co-treated with IFNG protein] results in increased expression of JUN protein; [beryllium sulfate co-treated with IFNG protein] results in increased expression of JUNB protein; [beryllium sulfate co-treated with IFNG protein] results in increased expression of NFKB1 protein; beryllium sulfate promotes the reaction [IFNG protein results in increased expression of TNF protein]
CTD PMID:10755710, PMID:10755711, PMID:20974702 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il18 interleukin 18 increases expression ISO beryllium sulfate results in increased expression of IL18 mRNA; beryllium sulfate results in increased expression of IL18 protein CTD PMID:16100009 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il2 interleukin 2 increases expression ISO beryllium sulfate results in increased expression of IL2 mRNA CTD PMID:9328138 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il5 interleukin 5 increases expression ISO beryllium sulfate results in increased expression of IL5 mRNA CTD PMID:9328138 NCBI chr10:39,066,716...39,069,587
Ensembl chr10:39,066,716...39,069,587
JBrowse link
G Il6 interleukin 6 increases expression ISO beryllium sulfate results in increased expression of IL6 mRNA CTD PMID:9328138 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Itgb3 integrin subunit beta 3 increases expression ISO beryllium sulfate results in increased expression of ITGB3 mRNA CTD PMID:16314022 NCBI chr10:92,667,869...92,783,413
Ensembl chr10:92,667,869...92,783,410
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [beryllium sulfate results in increased expression of JUN mRNA]; [beryllium sulfate co-treated with IFNG protein] results in increased expression of JUN protein; Dactinomycin inhibits the reaction [beryllium sulfate results in increased expression of JUN mRNA]; Ro 31-8220 inhibits the reaction [beryllium sulfate results in increased expression of JUN mRNA] CTD PMID:10755711, PMID:11568973 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [beryllium sulfate co-treated with IFNG protein] results in increased expression of JUNB protein CTD PMID:10755711 NCBI chr19:26,092,972...26,094,756
Ensembl chr19:26,092,974...26,094,756
JBrowse link
G LOC100364500 RT1 class I, locus CE11-like increases expression ISO beryllium sulfate results in increased expression of HLA-A mRNA CTD PMID:16314022 NCBI chr20:2,704,153...2,707,111
Ensembl chr20:2,704,148...2,707,120
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression EXP beryllium sulfate results in increased expression of MYC protein CTD PMID:2009323 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Nedd8 NEDD8 ubiquitin like modifier increases expression ISO beryllium sulfate results in increased expression of NEDD8 mRNA CTD PMID:16314022 NCBI chr15:34,340,607...34,352,673
Ensembl chr15:34,340,607...34,352,673
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO [beryllium sulfate co-treated with IFNG protein] results in increased expression of NFKB1 protein CTD PMID:10755711 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nova1 NOVA alternative splicing regulator 1 increases expression ISO beryllium sulfate results in increased expression of NOVA1 mRNA CTD PMID:16314022 NCBI chr 6:66,960,126...67,085,836
Ensembl chr 6:66,963,510...67,085,390
JBrowse link
G Rhoa ras homolog family member A increases expression ISO beryllium sulfate results in increased expression of RHOA mRNA CTD PMID:16314022 NCBI chr 8:117,082,440...117,116,244
Ensembl chr 8:117,106,576...117,116,167
JBrowse link
G Rpl22 ribosomal protein L22 increases expression ISO beryllium sulfate results in increased expression of RPL22 mRNA CTD PMID:16314022 NCBI chr 5:169,506,150...169,512,875
Ensembl chr 5:169,506,138...169,512,871
JBrowse link
G Rpl30 ribosomal protein L30 increases expression ISO beryllium sulfate results in increased expression of RPL30 mRNA CTD PMID:16314022 NCBI chr 7:73,213,538...73,216,431
Ensembl chr 7:73,213,581...73,216,251
JBrowse link
G Rpl37a ribosomal protein L37a increases expression ISO beryllium sulfate results in increased expression of RPL37A mRNA CTD PMID:16314022 NCBI chr 9:80,002,892...80,004,995 JBrowse link
G Rps7 ribosomal protein S7 increases expression ISO beryllium sulfate results in increased expression of RPS7 mRNA CTD PMID:16314022 NCBI chr 6:47,899,525...47,904,389
Ensembl chr 6:47,899,525...47,904,437
JBrowse link
G RT1-Db1 RT1 class II, locus Db1 increases response to substance
increases expression
ISO HLA-DRB1 protein mutant form results in increased susceptibility to beryllium sulfate
beryllium sulfate results in increased expression of HLA-DRB1 mRNA
CTD PMID:16272364, PMID:16314022 NCBI chr20:4,087,621...4,097,190
Ensembl chr20:4,087,618...4,097,190
JBrowse link
G Runx1 RUNX family transcription factor 1 multiple interactions ISO beryllium sulfate promotes the reaction [RUNX1 protein binds to CCL3 promoter] CTD PMID:16314022 NCBI chr11:32,765,147...33,003,061
Ensembl chr11:32,769,165...33,003,021
JBrowse link
G Serpinb2 serpin family B member 2 increases expression ISO beryllium sulfate results in increased expression of SERPINB2 mRNA CTD PMID:16314022 NCBI chr13:27,449,907...27,463,015
Ensembl chr13:27,449,934...27,463,010
JBrowse link
G Sftpd surfactant protein D increases expression ISO beryllium sulfate results in increased expression of SFTPD mRNA CTD PMID:16314022 NCBI chr16:18,753,535...18,766,100
Ensembl chr16:18,745,458...18,766,174
JBrowse link
G Tat tyrosine aminotransferase multiple interactions EXP beryllium sulfate inhibits the reaction [Hydrocortisone results in increased expression of TAT protein] CTD PMID:6120038 NCBI chr19:41,675,639...41,686,195
Ensembl chr19:41,675,355...41,686,229
JBrowse link
G Tmsb4x thymosin beta 4, X-linked increases expression ISO beryllium sulfate results in increased expression of TMSB4X mRNA CTD PMID:16314022 NCBI chr  X:28,593,405...28,617,267
Ensembl chr  X:28,593,405...28,595,395
JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions
ISO beryllium sulfate results in increased expression of TNF mRNA; beryllium sulfate results in increased expression of TNF protein
beryllium sulfate promotes the reaction [IFNG protein results in increased expression of TNF protein]
CTD PMID:10755710, PMID:10755711 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases expression
ISO beryllium sulfate promotes the reaction [TP53 protein binds to CDKN1A promoter]
beryllium sulfate results in increased expression of TP53 protein
CTD PMID:17395767, PMID:20974702 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Wnt4 Wnt family member 4 increases expression ISO beryllium sulfate results in increased expression of WNT4 mRNA CTD PMID:16314022 NCBI chr 5:155,649,238...155,668,065
Ensembl chr 5:155,649,217...155,672,579
JBrowse link
beryllium(0) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn2a cyclin-dependent kinase inhibitor 2A multiple interactions EXP [Beryllium results in increased methylation of CDKN2A promoter] which results in decreased expression of CDKN2A mRNA CTD PMID:11872642 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Esr1 estrogen receptor 1 increases methylation EXP Beryllium results in increased methylation of ESR1 gene CTD PMID:11872642 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Hras HRas proto-oncogene, GTPase increases mutagenesis EXP Beryllium results in increased mutagenesis of HRAS gene CTD PMID:7545909 NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
JBrowse link
G Il1b interleukin 1 beta increases expression
affects expression
ISO Beryllium results in increased expression of IL1B mRNA
Beryllium affects the expression of IL1B mRNA
CTD PMID:8473757, PMID:8629860 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Tnf tumor necrosis factor increases response to substance
increases expression
increases secretion
ISO TNF promoter polymorphism results in increased susceptibility to Beryllium
Beryllium results in increased expression of TNF mRNA
Beryllium results in increased secretion of TNF protein
CTD PMID:8629860, PMID:12449171, PMID:15127972 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
trifluoroberyllate(1-) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdxp pyridoxal phosphatase decreases activity ISO beryllium trifluoride results in decreased activity of PDXP protein CTD PMID:24338473 NCBI chr 7:120,140,460...120,145,908
Ensembl chr 7:120,140,460...120,145,908
JBrowse link
G Pgp phosphoglycolate phosphatase decreases activity ISO beryllium trifluoride results in decreased activity of PGP protein CTD PMID:24338473 NCBI chr10:13,836,105...13,838,731
Ensembl chr10:13,836,128...13,838,765
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19816
    role 19764
      biological role 19764
        epitope 6842
          beryllium atom 56
            beryllium molecular entity + 56
Path 2
Term Annotations click to browse term
  CHEBI ontology 19816
    subatomic particle 19814
      composite particle 19814
        hadron 19814
          baryon 19814
            nucleon 19814
              atomic nucleus 19814
                atom 19814
                  main group element atom 19702
                    alkaline earth metal atom 692
                      beryllium atom 56
                        beryllium molecular entity + 56
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.