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ONTOLOGY REPORT - ANNOTATIONS


Term:ethylene glycol
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Accession:CHEBI:30742 term browser browse the term
Definition:A 1,2-glycol compound produced via reaction of ethylene oxide with water.
Synonyms:related_synonym: 1,2-Dihydroxyethane;   1,2-ETHANEDIOL;   2-Hydroxyethanol;   Ethane-1,2-diol;   Ethanediol;   Formula=C2H6O2;   Glycol;   HO-CH2-CH2-OH;   InChI=1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2;   InChIKey=LYCAIKOWRPUZTN-UHFFFAOYSA-N;   Monoethylene glycol;   SMILES=OCCO
 alt_id: CHEBI:21317;   CHEBI:42277;   CHEBI:5473
 xref: Beilstein:505945 "Beilstein";   CAS:107-21-1 "ChemIDplus";   CAS:107-21-1 "KEGG COMPOUND";   CAS:107-21-1 "NIST Chemistry WebBook";   Gmelin:943 "Gmelin";   KEGG:C01380;   KEGG:C15588;   KNApSAcK:C00007409
 xref_mesh: MESH:D019855
 xref: MetaCyc:GLYCOL;   PDBeChem:EDO;   PMID:10349109 "Europe PMC";   PMID:15716482 "Europe PMC";   PMID:16901854 "Europe PMC";   PMID:17186009 "Europe PMC";   PMID:17336832 "Europe PMC";   PMID:17439666 "Europe PMC";   PMID:17979222 "Europe PMC";   PMID:18612987 "Europe PMC";   PMID:23764541 "Europe PMC";   PMID:23827374 "Europe PMC";   PMID:24045699 "Europe PMC";   PMID:24643482 "Europe PMC";   PMID:25108762 "Europe PMC";   PMID:9463526 "Europe PMC";   PPDB:1310;   Reaxys:505945 "Reaxys";   UM-BBD_compID:c0542 "UM-BBD";   Wikipedia:Ethylene_Glycol


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ethylene glycol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adh1 alcohol dehydrogenase 1 (class I) JBrowse link 2 243,550,655 243,562,243 RGD:6480464
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide JBrowse link 2 243,702,035 243,720,063 RGD:6480464
G Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide JBrowse link 2 243,500,540 243,516,865 RGD:6480464
G C5 complement C5 JBrowse link 3
3
14,049,993
14,206,466
14,113,931
14,229,141
RGD:6480464
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:6480464
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:6480464
G Ccl5 C-C motif chemokine ligand 5 JBrowse link 10 70,739,764 70,744,303 RGD:6480464
G Gh1 growth hormone 1 JBrowse link 10 94,486,204 94,488,181 RGD:6480464
G Havcr1 hepatitis A virus cellular receptor 1 JBrowse link 10 31,813,819 31,860,934 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Nefh neurofilament heavy JBrowse link 14 85,181,572 85,191,557 RGD:6480464
G Nfkb1 nuclear factor kappa B subunit 1 JBrowse link 2 240,773,520 240,890,053 RGD:6480464
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6480464
G Slc26a1 solute carrier family 26 member 1 JBrowse link 14 2,050,805 2,056,091 RGD:6480464
G Spp1 secreted phosphoprotein 1 JBrowse link 14 6,673,686 6,679,965 RGD:6480464
G Tf transferrin JBrowse link 8 111,694,570 111,721,275 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Umod uromodulin JBrowse link 1 189,186,027 189,199,939 RGD:6480464
G Vnn1 vanin 1 JBrowse link 1 22,614,832 22,625,134 RGD:6480464
2-ethoxyethanol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akt2 AKT serine/threonine kinase 2 JBrowse link 1 84,400,939 84,451,223 RGD:6480464
G Akt3 AKT serine/threonine kinase 3 JBrowse link 13 95,076,308 95,348,913 RGD:6480464
G Aldh2 aldehyde dehydrogenase 2 family member JBrowse link 12 40,466,418 40,498,813 RGD:6480464
G App amyloid beta precursor protein JBrowse link 11 24,425,013 24,641,872 RGD:6480464
G Arf3 ADP-ribosylation factor 3 JBrowse link 7 140,412,463 140,438,751 RGD:6480464
G Atf2 activating transcription factor 2 JBrowse link 3 60,721,137 60,795,951 RGD:6480464
G Bag6 BCL2-associated athanogene 6 JBrowse link 20 5,124,512 5,138,084 RGD:6480464
G Bcl2l1 Bcl2-like 1 JBrowse link 3 148,259,594 148,314,191 RGD:6480464
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:6480464
G Cav1 caveolin 1 JBrowse link 4 44,597,123 44,630,206 RGD:6480464
G Cebpg CCAAT/enhancer binding protein gamma JBrowse link 1 91,286,956 91,297,459 RGD:6480464
G Cel carboxyl ester lipase JBrowse link 3 7,134,021 7,141,522 RGD:6480464
G Chp1 calcineurin-like EF-hand protein 1 JBrowse link 3 111,354,506 111,389,998 RGD:6480464
G Cltc clathrin heavy chain JBrowse link 10 74,014,560 74,070,578 RGD:6480464
G Csnk1a1 casein kinase 1, alpha 1 JBrowse link 18 56,887,722 56,910,610 RGD:6480464
G Csnk1d casein kinase 1, delta JBrowse link 10 110,147,786 110,182,413 RGD:6480464
G Csnk1g3 casein kinase 1, gamma 3 JBrowse link 18 48,831,209 48,913,341 RGD:6480464
G Cttn cortactin JBrowse link 1
1
217,602,698
215,255,385
217,638,196
215,290,882
RGD:6480464
G Dhcr7 7-dehydrocholesterol reductase JBrowse link 1 217,018,916 217,034,890 RGD:6480464
G Dync1li1 dynein cytoplasmic 1 light intermediate chain 1 JBrowse link 8 122,743,274 122,776,801 RGD:6480464
G Eloa elongin A JBrowse link 5 154,348,167 154,363,324 RGD:6480464
G Eno2 enolase 2 JBrowse link 4 157,285,192 157,294,090 RGD:6480464
G Epn2 epsin 2 JBrowse link 10 47,795,496 47,857,373 RGD:6480464
G Gata4 GATA binding protein 4 JBrowse link 15 46,386,703 46,458,679 RGD:6480464
G Gata6 GATA binding protein 6 JBrowse link 18 2,415,821 2,447,087 RGD:6480464
G Gdi2 GDP dissociation inhibitor 2 JBrowse link 17 70,299,177 70,325,864 RGD:6480464
G Hk1 hexokinase 1 JBrowse link 20 31,911,460 31,979,780 RGD:6480464
G Hk2 hexokinase 2 JBrowse link 4 113,559,396 113,609,897 RGD:6480464
G Igf2 insulin-like growth factor 2 JBrowse link 1 215,828,102 215,839,081 RGD:6480464
G Jak2 Janus kinase 2 JBrowse link 1 247,398,667 247,457,521 RGD:6480464
G Lyn LYN proto-oncogene, Src family tyrosine kinase JBrowse link 5 16,526,058 16,642,648 RGD:6480464
G Map3k12 mitogen activated protein kinase kinase kinase 12 JBrowse link 7 144,102,275 144,120,306 RGD:6480464
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6480464
G Mapk10 mitogen activated protein kinase 10 JBrowse link 14 8,079,955 8,371,508 RGD:6480464
G Mxi1 MAX interactor 1, dimerization protein JBrowse link 1 274,030,748 274,090,071 RGD:6480464
G Nab1 Ngfi-A binding protein 1 JBrowse link 9 53,906,073 53,945,474 RGD:6480464
G Nfia nuclear factor I/A JBrowse link 5 116,421,895 116,750,381 RGD:6480464
G Nr2f2 nuclear receptor subfamily 2, group F, member 2 JBrowse link 1 131,447,671 131,465,749 RGD:6480464
G Pak2 p21 (RAC1) activated kinase 2 JBrowse link 11 72,829,407 72,865,815 RGD:6480464
G Pfkfb2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 JBrowse link 13 47,413,453 47,440,682 RGD:6480464
G Pla2g4a phospholipase A2 group IVA JBrowse link 13 67,062,252 67,206,688 RGD:6480464
G Plcb3 phospholipase C beta 3 JBrowse link 1 222,207,887 222,224,993 RGD:6480464
G Pou2f3 POU class 2 homeobox 3 JBrowse link 8 47,412,063 47,495,042 RGD:6480464
G Prkar2a protein kinase cAMP-dependent type II regulatory subunit alpha JBrowse link 8 117,486,085 117,548,768 RGD:6480464
G Rab5a RAB5A, member RAS oncogene family JBrowse link 9 5,910 6,065 RGD:6480464
G Rnf4 ring finger protein 4 JBrowse link 14 81,658,400 81,679,756 RGD:6480464
G Ros1 ROS proto-oncogene 1 , receptor tyrosine kinase JBrowse link 20 33,100,190 33,323,544 RGD:6480464
G Sec14l2 SEC14-like lipid binding 2 JBrowse link 14 84,335,594 84,360,354 RGD:6480464
G Sik1 salt-inducible kinase 1 JBrowse link 20 10,670,747 10,680,279 RGD:6480464
G Snrk SNF related kinase JBrowse link 8 130,749,806 130,805,225 RGD:6480464
G Snx16 sorting nexin 16 JBrowse link 2 93,518,796 93,541,056 RGD:6480464
G Soat1 sterol O-acyltransferase 1 JBrowse link 13 74,035,258 74,077,759 RGD:6480464
G Stk17b serine/threonine kinase 17b JBrowse link 9 60,399,261 60,430,081 RGD:6480464
G Stx2 syntaxin 2 JBrowse link 12 31,324,203 31,360,249 RGD:6480464
G Stxbp1 syntaxin binding protein 1 JBrowse link 3 11,823,779 11,885,479 RGD:6480464
G Sycp1 synaptonemal complex protein 1 JBrowse link 2 205,274,766 205,426,869 RGD:6480464
G Sycp2 synaptonemal complex protein 2 JBrowse link 3 173,884,559 173,948,304 RGD:6480464
G Sycp3 synaptonemal complex protein 3 JBrowse link 7 29,029,887 29,044,344 RGD:6480464
G Tle4 TLE family member 4, transcriptional corepressor JBrowse link 1 231,394,606 231,531,396 RGD:6480464
G Tmed2 transmembrane p24 trafficking protein 2 JBrowse link 12 37,471,259 37,480,344 RGD:6480464
G Wt1 WT1 transcription factor JBrowse link 3 95,133,221 95,180,574 RGD:6480464
G Yy1 YY1 transcription factor JBrowse link 6 132,702,443 132,726,848 RGD:6480464
2-hydroxyethyl methacrylate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atg5 autophagy related 5 JBrowse link 20 49,301,783 49,393,147 RGD:6480464
G Becn1 beclin 1 JBrowse link 10 89,209,944 89,225,297 RGD:6480464
G Casp9 caspase 9 JBrowse link 5 160,356,211 160,373,774 RGD:6480464
G Col1a1 collagen type I alpha 1 chain JBrowse link 10 82,745,801 82,762,790 RGD:6480464
G Fgf2 fibroblast growth factor 2 JBrowse link 2 124,081,072 124,134,133 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Map1lc3b microtubule-associated protein 1 light chain 3 beta JBrowse link 19 53,635,449 53,643,970 RGD:6480464
G Nfkbia NFKB inhibitor alpha JBrowse link 6 76,267,227 76,270,457 RGD:6480464
G Parp1 poly (ADP-ribose) polymerase 1 JBrowse link 13 98,857,255 98,889,444 RGD:6480464
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:6480464
ethylene glycol dimethacrylate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akr1c2 aldo-keto reductase family 1, member C2 JBrowse link 17 69,388,337 69,435,160 RGD:6480464
G Atf3 activating transcription factor 3 JBrowse link 13 109,817,892 109,849,632 RGD:6480464
G Bach1 BTB domain and CNC homolog 1 JBrowse link 11 27,364,913 27,398,713 RGD:6480464
G Cd86 CD86 molecule JBrowse link 11 67,060,305 67,117,990 RGD:6480464
G Cxcl2 C-X-C motif chemokine ligand 2 JBrowse link 14 18,731,346 18,733,391 RGD:6480464
G Gclm glutamate cysteine ligase, modifier subunit JBrowse link 2 225,827,504 225,847,876 RGD:6480464
G Gpx4 glutathione peroxidase 4 JBrowse link 7 12,516,357 12,519,154 RGD:6480464
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:6480464
G Il1a interleukin 1 alpha JBrowse link 3 121,824,712 121,836,122 RGD:6480464
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:6480464
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:6480464
macitentan term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb1a ATP binding cassette subfamily B member 1A JBrowse link 4 22,339,829 22,517,642 RGD:6480464
G Abcc2 ATP binding cassette subfamily C member 2 JBrowse link 1 263,554,426 263,612,556 RGD:6480464
G Abcc3 ATP binding cassette subfamily C member 3 JBrowse link 10 82,047,308 82,116,928 RGD:6480464
G Slc10a1 solute carrier family 10 member 1 JBrowse link 6 104,617,730 104,631,355 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      chemical role 19128
        solvent 16070
          ethylene glycol 105
            1,2-dimethoxyethane 0
            2-ethoxyethanol + 62
            2-hydroxyethyl hexadecanoate 0
            2-hydroxyethyl methacrylate 13
            2-hydroxyethyl salicylate 0
            2-hydroxyethyl sulfonate 0
            4-[(2-hydroxyethoxy)carbonyl]benzoic acid 0
            6-(2-hydroxyethoxy)-6-oxohexanoic acid 0
            ACT-132577 + 4
            TCA-ethadyl 0
            ethylene glycol bis(2-aminoethyl)tetraacetate 0
            ethylene glycol dimethacrylate 11
            ethylene glycol monododecyl ether 0
            ethylene glycol monophosphate 0
            macitentan 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    p-block element atom 19545
                      chalcogen 19233
                        oxygen atom 19188
                          oxygen molecular entity 19188
                            hydroxides 18965
                              organic hydroxy compound 18507
                                polyol 7564
                                  diol 2687
                                    glycol 2416
                                      ethylene glycol 105
                                        1,2-dimethoxyethane 0
                                        2-ethoxyethanol + 62
                                        2-hydroxyethyl hexadecanoate 0
                                        2-hydroxyethyl methacrylate 13
                                        2-hydroxyethyl salicylate 0
                                        2-hydroxyethyl sulfonate 0
                                        4-[(2-hydroxyethoxy)carbonyl]benzoic acid 0
                                        6-(2-hydroxyethoxy)-6-oxohexanoic acid 0
                                        ACT-132577 + 4
                                        TCA-ethadyl 0
                                        ethylene glycol bis(2-aminoethyl)tetraacetate 0
                                        ethylene glycol dimethacrylate 11
                                        ethylene glycol monododecyl ether 0
                                        ethylene glycol monophosphate 0
                                        macitentan 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.