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Term:methylmalonic acid
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Accession:CHEBI:30860 term browser browse the term
Definition:A dicarboxylic acid that is malonic acid in which one of the methylene hydrogens is substituted by a methyl group.
Synonyms:related_synonym: 1,1-Ethanedicarboxylic acid;   2-methylmalonic acid;   Formula=C4H6O4;   InChI=1S/C4H6O4/c1-2(3(5)6)4(7)8/h2H,1H3,(H,5,6)(H,7,8);   InChIKey=ZIYVHBGGAOATLY-UHFFFAOYSA-N;   Isosuccinic acid;   Methylpropanedioic acid;   SMILES=CC(C(O)=O)C(O)=O;   alpha-methylmalonic acid
 alt_id: CHEBI:25319;   CHEBI:42270;   CHEBI:6881
 xref: Beilstein:1756084 "Beilstein";   CAS:516-05-2 "ChemIDplus";   CAS:516-05-2 "KEGG COMPOUND";   CAS:516-05-2 "NIST Chemistry WebBook";   DrugBank:DB04183;   Gmelin:50008 "Gmelin";   HMDB:HMDB0000202;   KEGG:C02170;   LIPID_MAPS_instance:LMFA01170118 "LIPID MAPS"
 xref_mesh: MESH:D008764
 xref: MetaCyc:CPD-546;   PDBeChem:DXX;   PMID:11673368 "Europe PMC";   PMID:15770414 "Europe PMC";   PMID:17190852 "Europe PMC";   PMID:21478039 "Europe PMC";   PMID:21652239 "Europe PMC";   PMID:21687976 "Europe PMC";   PMID:21748409 "Europe PMC";   PMID:21802231 "Europe PMC";   PMID:21896502 "Europe PMC";   PMID:22104738 "Europe PMC";   PMID:22233538 "Europe PMC";   PMID:22301932 "Europe PMC";   PMID:22332180 "Europe PMC";   PMID:22377700 "Europe PMC";   PMID:22422209 "Europe PMC";   PMID:22424943 "Europe PMC";   PMID:22509143 "Europe PMC";   PMID:22537172 "Europe PMC";   PMID:22770225 "Europe PMC";   Reaxys:1756084 "Reaxys";   Wikipedia:Methylmalonic_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:30861

show annotations for term's descendants       view all columns           Sort by:
methylmalonic acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aif1 allograft inflammatory factor 1 JBrowse link 20 5,161,350 5,167,176 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Lepr leptin receptor JBrowse link 5 120,503,475 120,682,281 RGD:6480464
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19716
    role 19663
      biological role 19661
        biochemical role 19179
          metabolite 19151
            eukaryotic metabolite 18770
              animal metabolite 18511
                mammalian metabolite 18493
                  human metabolite 18133
                    methylmalonic acid 6
                      O-methylmalonyl-L-carnitine 0
                      aryl(methyl)malonic acid + 0
                      methylmalonyl-CoA + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19716
    subatomic particle 19712
      composite particle 19712
        hadron 19712
          baryon 19712
            nucleon 19712
              atomic nucleus 19712
                atom 19712
                  main group element atom 19598
                    p-block element atom 19598
                      carbon group element atom 19486
                        carbon atom 19480
                          organic molecular entity 19480
                            organic group 18407
                              organic divalent group 18397
                                organodiyl group 18397
                                  carbonyl group 18285
                                    carbonyl compound 18285
                                      dicarboxylic acids and O-substituted derivatives 10209
                                        dicarboxylic acid 10203
                                          alpha,omega-dicarboxylic acid 2743
                                            malonic acid 58
                                              methylmalonic acid 6
                                                O-methylmalonyl-L-carnitine 0
                                                aryl(methyl)malonic acid + 0
                                                methylmalonyl-CoA + 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.