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ONTOLOGY REPORT - ANNOTATIONS


Term:13-dihydrodaunorubicin
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Accession:CHEBI:31059 term browser browse the term
Definition:An aminoglycoside antibiotic that is (1S,3S)-3,5,12-trihydroxy-3-(1-hydroxyethyl)-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracene having a 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl residue attached at position 1 via a glycosidic linkage.
Synonyms:exact_synonym: (1S,3S)-3,5,12-trihydroxy-3-(1-hydroxyethyl)-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside
 related_synonym: 1-Hydroxy-13-dihydrodaunomycin;   13-Dihydrodaunomycin;   Antibiotic 20-798RP;   Daunomycinol;   Daunorubicinol;   Dihydrodaunomycin;   Duborimycin;   Formula=C27H31NO10;   InChI=1S/C27H31NO10/c1-10-22(30)14(28)7-17(37-10)38-16-9-27(35,11(2)29)8-13-19(16)26(34)21-20(24(13)32)23(31)12-5-4-6-15(36-3)18(12)25(21)33/h4-6,10-11,14,16-17,22,29-30,32,34-35H,7-9,28H2,1-3H3/t10-,11?,14-,16-,17-,22+,27-/m0/s1;   InChIKey=HJEZFVLKJYFNQW-FKKRWUELSA-N;   Leukaemomycin D;   SMILES=COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(C)O
 xref: CAS:28008-55-1 "ChemIDplus";   CAS:28008-55-1 "KEGG COMPOUND";   KEGG:C12430;   LIPID_MAPS_instance:LMPK13050004 "LIPID MAPS"
 xref_mesh: MESH:C000847
 xref: PMID:9098063 "Europe PMC";   PMID:9864343 "Europe PMC";   Reaxys:6773802 "Reaxys"
 cyclic_relationship: is_conjugate_base_of CHEBI:75296


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13-dihydrodaunorubicin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akr1a1 aldo-keto reductase family 1 member A1 JBrowse link 5 135,482,068 135,498,693 RGD:6480464
G Akr1b10 aldo-keto reductase family 1 member B10 JBrowse link 4 61,813,265 61,830,371 RGD:6480464
G Akr1c3 aldo-keto reductase family 1, member C3 JBrowse link 17 69,761,126 69,778,021 RGD:6480464
G Cbr1 carbonyl reductase 1 JBrowse link 11 33,813,041 33,815,418 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19741
    role 19688
      biological role 19686
        antimicrobial agent 17215
          carbohydrate-containing antibiotic 2542
            aminoglycoside antibiotic 2525
              13-dihydrodaunorubicin 4
                (13S)-13-dihydrodaunorubicin 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19741
    subatomic particle 19737
      composite particle 19737
        hadron 19737
          baryon 19737
            nucleon 19737
              atomic nucleus 19737
                atom 19737
                  main group element atom 19622
                    p-block element atom 19622
                      carbon group element atom 19515
                        carbon atom 19508
                          organic molecular entity 19508
                            heteroorganic entity 19067
                              organochalcogen compound 18792
                                organooxygen compound 18704
                                  carbohydrates and carbohydrate derivatives 12099
                                    carbohydrate 12099
                                      carbohydrate derivative 11725
                                        glycosyl compound 10784
                                          glycoside 9136
                                            aminoglycoside 8349
                                              aminoglycoside antibiotic 2525
                                                13-dihydrodaunorubicin 4
                                                  (13S)-13-dihydrodaunorubicin 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.