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ONTOLOGY REPORT - ANNOTATIONS


Term:acemetacin
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Accession:CHEBI:31162 term browser browse the term
Definition:A carboxylic ester that is the carboxymethyl ester of indometacin. A non-steroidal anti-inflammatory drug, it is used in the treatment of rheumatoid arthritis, osteoarthritis, and low back pain, as well as for postoperative pain and inflammation. Its activity is due to both acemetacin and its major metabolite, indometacin.
Synonyms:exact_synonym: {2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetoxy}acetic acid
 related_synonym: Acemix;   Emflex;   Formula=C21H18ClNO6;   InChI=1S/C21H18ClNO6/c1-12-16(10-20(26)29-11-19(24)25)17-9-15(28-2)7-8-18(17)23(12)21(27)13-3-5-14(22)6-4-13/h3-9H,10-11H2,1-2H3,(H,24,25);   InChIKey=FSQKKOOTNAMONP-UHFFFAOYSA-N;   K-708;   Rantudil;   SMILES=COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)OCC(O)=O)c2c1;   Solart;   TV-1322;   TVX 3322;   acemetacina;   acemetacine;   acemetacinum;   indometacin carboxymethyl ester;   indometacin glycolic ester;   indomethacin carboxymethyl ester;   indomethacin glycolic ester
 xref: CAS:53164-05-9 "ChemIDplus";   Drug_Central:47 "DrugCentral";   KEGG:D01582;   LINCS:LSM-5753
 xref_mesh: MESH:C026784
 xref: Patent:DE2234651;   Patent:US3910952;   Reaxys:501672 "Reaxys";   Wikipedia:Acemetacin


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acemetacin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Glo1 glyoxalase 1 JBrowse link 20 9,273,589 9,291,608 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19741
    role 19688
      biological role 19686
        xenobiotic 18322
          indometacin 3158
            acemetacin 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19741
    subatomic particle 19737
      composite particle 19737
        hadron 19737
          baryon 19737
            nucleon 19737
              atomic nucleus 19737
                atom 19737
                  main group element atom 19622
                    p-block element atom 19622
                      carbon group element atom 19515
                        carbon atom 19508
                          organic molecular entity 19508
                            organic group 18423
                              organic divalent group 18414
                                organodiyl group 18414
                                  carbonyl group 18301
                                    carbonyl compound 18301
                                      carboxylic acid 17966
                                        carboacyl group 17073
                                          univalent carboacyl group 17073
                                            carbamoyl group 16800
                                              carboxamide 16800
                                                N-acylindole 3158
                                                  indometacin 3158
                                                    acemetacin 1
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