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ONTOLOGY REPORT - ANNOTATIONS


Term:adapalene
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Accession:CHEBI:31174 term browser browse the term
Definition:A naphthoic acid that is CD437 in which the phenolic hydroxy group has been converted to its methyl ether.
Synonyms:exact_synonym: 6-(3-adamantan-1-yl-4-methoxyphenyl)naphthalene-2-carboxylic acid
 related_synonym: 6-(3-(1-Adamantyl)-4-methoxyphenyl)-2-naphthoic acid;   Adaferin;   Differine;   Formula=C28H28O3;   InChI=1S/C28H28O3/c1-31-26-7-6-23(21-2-3-22-12-24(27(29)30)5-4-20(22)11-21)13-25(26)28-14-17-8-18(15-28)10-19(9-17)16-28/h2-7,11-13,17-19H,8-10,14-16H2,1H3,(H,29,30);   InChIKey=LZCDAPDGXCYOEH-UHFFFAOYSA-N;   SMILES=C1C2(CC3CC(CC1C3)C2)C4=C(C=CC(=C4)C5=CC=C6C(=C5)C=CC(=C6)C(=O)O)OC;   adapaleno;   adapalenum
 xref: CAS:106685-40-9 "ChemIDplus";   DrugBank:DB00210;   Drug_Central:87 "DrugCentral";   KEGG:D01112;   LINCS:LSM-37048
 xref_mesh: MESH:C063610
 xref: PMID:11594670 "Europe PMC";   PMID:12833014 "Europe PMC";   PMID:25016424 "Europe PMC";   PMID:26398439 "Europe PMC";   PMID:26483036 "Europe PMC";   Patent:EP199636;   Patent:US4717720;   Wikipedia:Adapalene


show annotations for term's descendants       view all columns           Sort by:
 
adapalene term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd1d1 CD1d1 molecule JBrowse link 2 186,330,298 186,333,805 RGD:6480464
G Crabp2 cellular retinoic acid binding protein 2 JBrowse link 2 187,322,416 187,326,794 RGD:6480464
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:6480464
G Rarg retinoic acid receptor, gamma JBrowse link 7 143,840,739 143,863,206 RGD:6480464
G Slc22a2 solute carrier family 22 member 2 JBrowse link 1 48,318,025 48,360,219 RGD:6480464
G Tlr2 toll-like receptor 2 JBrowse link 2 182,840,171 182,846,061 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19728
    role 19675
      application 19328
        anti-inflammatory agent 14935
          anti-inflammatory drug 13586
            non-steroidal anti-inflammatory drug 12671
              adapalene 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19728
    subatomic particle 19724
      composite particle 19724
        hadron 19724
          baryon 19724
            nucleon 19724
              atomic nucleus 19724
                atom 19724
                  main group element atom 19610
                    p-block element atom 19610
                      carbon group element atom 19501
                        carbon atom 19494
                          organic molecular entity 19494
                            organic group 18413
                              organic divalent group 18404
                                organodiyl group 18404
                                  carbonyl group 18293
                                    carbonyl compound 18293
                                      carboxylic acid 17960
                                        aromatic carboxylic acid 10732
                                          naphthoic acid 43
                                            CD437 6
                                              adapalene 6
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