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ONTOLOGY REPORT - ANNOTATIONS


Term:betamethasone dipropionate
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Accession:CHEBI:31276 term browser browse the term
Definition:A steroid ester that is betamethasone in which the hydroxy hydrogens at positions 17 and 21 are replaced by propanoyl groups. It is used in combination with calcipotriene hydrate, a synthetic vitamin D analogue, for the topical treatment of plaque psoriasis in adult patients.
Synonyms:exact_synonym: 9-fluoro-11beta-hydroxy-16beta-methyl-3,20-dioxopregna-1,4-diene-17,21-diyl dipropanoate
 related_synonym: 9-Fluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione-17,21-dipropionate;   Betamethasone 17,21-dipropionate;   Formula=C28H37FO7;   InChI=1S/C28H37FO7/c1-6-23(33)35-15-22(32)28(36-24(34)7-2)16(3)12-20-19-9-8-17-13-18(30)10-11-25(17,4)27(19,29)21(31)14-26(20,28)5/h10-11,13,16,19-21,31H,6-9,12,14-15H2,1-5H3/t16-,19-,20-,21-,25-,26-,27-,28-/m0/s1;   InChIKey=CIWBQSYVNNPZIQ-XYWKZLDCSA-N;   SMILES=[H][C@@]12C[C@H](C)[C@](OC(=O)CC)(C(=O)COC(=O)CC)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])CCC2=CC(=O)C=C[C@]12C
 xref: Beilstein:3638108 "Beilstein";   CAS:5593-20-4 "ChemIDplus";   DrugBank:DB00443;   Drug_Central:353 "DrugCentral";   KEGG:D01637
 xref_mesh: MESH:C011175
 xref: PMID:23621170 "Europe PMC";   PMID:24533503 "Europe PMC";   PMID:24593129 "Europe PMC";   PMID:24684739 "Europe PMC";   PMID:24684740 "Europe PMC";   PMID:24980277 "Europe PMC";   PMID:25279474 "Europe PMC";   PMID:25307472 "Europe PMC";   PMID:25355140 "Europe PMC";   PMID:25410121 "Europe PMC";   PMID:25412565 "Europe PMC";   PMID:25556056 "Europe PMC";   PMID:25566573 "Europe PMC";   PMID:25607705 "Europe PMC";   PMID:26094549 "Europe PMC";   PMID:26444907 "Europe PMC";   PMID:26659941 "Europe PMC";   Reaxys:3638108 "Reaxys";   Wikipedia:Betamethasone_Dipropionate


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betamethasone dipropionate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19741
    role 19688
      application 19339
        anti-asthmatic agent 9176
          betamethasone 24
            betamethasone dipropionate 1
              Enstilar 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19741
    subatomic particle 19737
      composite particle 19737
        hadron 19737
          baryon 19737
            nucleon 19737
              atomic nucleus 19737
                atom 19737
                  main group element atom 19622
                    p-block element atom 19622
                      carbon group element atom 19515
                        carbon atom 19508
                          organic molecular entity 19508
                            organic group 18423
                              organic divalent group 18414
                                organodiyl group 18414
                                  carbonyl group 18301
                                    carbonyl compound 18301
                                      ketone 15918
                                        oxyketone 8453
                                          alpha-oxyketone 8453
                                            alpha-hydroxy ketone 8453
                                              primary alpha-hydroxy ketone 7443
                                                betamethasone 24
                                                  betamethasone dipropionate 1
                                                    Enstilar 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.