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ONTOLOGY REPORT - ANNOTATIONS


Term:bithionol
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Accession:CHEBI:3131 term browser browse the term
Definition:An aryl sulfide that is diphenyl sulfide in which each phenyl group is substituted at position 2 by hydroxy and at positions 3 and 5 by chlorine. A fungicide and anthelmintic, it was used in various topical drug products for the treatment of liver flukes, but withdrawn after being shown to be a potent photosensitizer with the potential to cause serious skin disorders.
Synonyms:exact_synonym: 2,2'-sulfanediylbis(4,6-dichlorophenol)
 related_synonym: 2,2'-Dihydroxy-3,3',5,5'-tetrachlorodiphenyl sulfide;   2,2'-Thiobis(4,6-dichlorophenol);   2-Hydroxy-3,5-dichlorophenyl sulfide;   Bis(3,5-dichloro-2-hydroxyphenyl) sulfide;   Bithin;   Bithionol sulfide;   Formula=C12H6Cl4O2S;   InChI=1S/C12H6Cl4O2S/c13-5-1-7(15)11(17)9(3-5)19-10-4-6(14)2-8(16)12(10)18/h1-4,17-18H;   InChIKey=JFIOVJDNOJYLKP-UHFFFAOYSA-N;   SMILES=Oc1c(Cl)cc(Cl)cc1Sc1cc(Cl)cc(Cl)c1O
 xref: Beilstein:2003535 "Beilstein";   CAS:97-18-7 "ChemIDplus";   CAS:97-18-7 "KEGG COMPOUND";   CAS:97-18-7 "NIST Chemistry WebBook";   DrugBank:DB04813;   Drug_Central:3032 "DrugCentral";   KEGG:C07967;   KEGG:D00802;   LINCS:LSM-2862
 xref_mesh: MESH:D001735
 xref: PDBeChem:B1T;   PMID:17129675 "Europe PMC";   PMID:24495391 "Europe PMC";   PPDB:2889;   Pesticides:bithionol "Alan Wood's Pesticides";   VSDB:2889;   Wikipedia:Bithionol


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bithionol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slc22a2 solute carrier family 22 member 2 JBrowse link 1 48,318,025 48,360,219 RGD:6480464
G Thra thyroid hormone receptor alpha JBrowse link 10 86,657,285 86,684,935 RGD:6480464
G Thrb thyroid hormone receptor beta JBrowse link 15 8,890,578 9,239,815 RGD:6480464

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  CHEBI ontology 19679
    role 19623
      application 19246
        pesticide 15810
          organochlorine pesticide 5919
            bithionol 3
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  CHEBI ontology 19679
    subatomic particle 19675
      composite particle 19675
        hadron 19675
          baryon 19675
            nucleon 19675
              atomic nucleus 19675
                atom 19675
                  main group element atom 19555
                    p-block element atom 19555
                      carbon group element atom 19438
                        carbon atom 19430
                          organic molecular entity 19430
                            organic molecule 19353
                              organic cyclic compound 19102
                                carbocyclic compound 17516
                                  benzenoid aromatic compound 17038
                                    benzenes 16752
                                      chlorobenzenes 12584
                                        dichlorobenzene 9683
                                          bithionol 3
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