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ONTOLOGY REPORT - ANNOTATIONS


Term:crotamiton
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Accession:CHEBI:31439 term browser browse the term
Definition:An enamide resulting from the formal condensation of crotonic acid with N-ethyl-2-methylaniline. A colourless or pale yellow oily liquid, it is used in the treatment of pruritus (itching) by producing a counter-irritation: as it evaporates from the skin, it produces a cooling effect that diverts attention away from the itching. It has also been used as an acaricide in the treatment of scabies, though more effective drugs are usually preferred.
Synonyms:exact_synonym: N-ethyl-N-(2-methylphenyl)but-2-enamide
 related_synonym: Formula=C13H17NO;   InChI=1S/C13H17NO/c1-4-8-13(15)14(5-2)12-10-7-6-9-11(12)3/h4,6-10H,5H2,1-3H3;   InChIKey=DNTGGZPQPQTDQF-UHFFFAOYSA-N;   N-ethyl-o-crotonotoluidide;   SMILES=CCN(C(=O)C=CC)c1ccccc1C;   crotalgin;   crotamitone;   crotamitonum;   crotonyl-N-ethyl-o-toluidine
 xref: Beilstein:3275497;   CAS:483-63-6;   DrugBank:DB00265;   Drug_Central:744;   KEGG:D01381;   LINCS:LSM-3274
 xref_mesh: MESH:C005553
 xref: Patent:GB615137


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crotamiton term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 JBrowse link 13 89,585,072 89,591,278 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19770
    role 19717
      application 19366
        pesticide 16190
          acaricide 9049
            scabicide 454
              crotamiton 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19770
    subatomic particle 19768
      composite particle 19768
        hadron 19768
          baryon 19768
            nucleon 19768
              atomic nucleus 19768
                atom 19768
                  main group element atom 19653
                    p-block element atom 19653
                      carbon group element atom 19548
                        carbon atom 19537
                          organic molecular entity 19537
                            organic group 18465
                              organic divalent group 18458
                                organodiyl group 18458
                                  carbonyl group 18354
                                    carbonyl compound 18354
                                      carboxylic acid 18033
                                        carboacyl group 17190
                                          univalent carboacyl group 17190
                                            carbamoyl group 16927
                                              carboxamide 16927
                                                alpha,beta-unsaturated carboxylic acid amide 4756
                                                  enamide 4756
                                                    crotamiton 1
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