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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Iguratimod
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Accession:CHEBI:31689 term browser browse the term
Synonyms:related_synonym: Formula=C17H14N2O6S;   InChI=1S/C17H14N2O6S/c1-26(22,23)19-13-8-15-12(17(21)14(9-24-15)18-10-20)7-16(13)25-11-5-3-2-4-6-11/h2-10,19H,1H3,(H,18,20);   InChIKey=ANMATWQYLIFGOK-UHFFFAOYSA-N;   SMILES=C1=C(C(=CC2=C1OC=C(C2=O)NC=O)OC3=CC=CC=C3)NS(C)(=O)=O;   T-614;   careram;   kolbet
 xref: CAS:123663-49-0;   Drug_Central:4894;   KEGG:D01146
 xref_mesh: MESH:C077313


show annotations for term's descendants           Sort by:
 
Iguratimod term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1b interleukin 1 beta decreases expression
multiple interactions
EXP T 614 results in decreased expression of IL1B protein
Methotrexate promotes the reaction [T 614 results in decreased expression of IL1B protein]
CTD PMID:19019215 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 decreases expression
multiple interactions
EXP T 614 results in decreased expression of IL6 protein
Methotrexate promotes the reaction [T 614 results in decreased expression of IL6 protein]
CTD PMID:19019215 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Tnf tumor necrosis factor decreases expression
multiple interactions
EXP T 614 results in decreased expression of TNF protein
Methotrexate promotes the reaction [T 614 results in decreased expression of TNF protein]
CTD PMID:19019215 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19810
    chemical entity 19810
      atom 19808
        nonmetal atom 19683
          carbon atom 19588
            organic molecular entity 19588
              Iguratimod 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    p-block element atom 19696
                      carbon group element atom 19599
                        carbon atom 19588
                          organic molecular entity 19588
                            Iguratimod 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.