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ONTOLOGY REPORT - ANNOTATIONS


Term:brompheniramine
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Accession:CHEBI:3183 term browser browse the term
Definition:Pheniramine in which the hydrogen at position 4 of the phenyl substituent is substituted by bromine. A histamine H1 receptor antagonist, brompheniramine is used (commonly as its maleate salt) for the symptomatic relief of allergic conditions, including rhinitis and conjunctivitis.
Synonyms:exact_synonym: 3-(4-bromophenyl)-N,N-dimethyl-3-(pyridin-2-yl)propan-1-amine
 related_synonym: 1-(p-bromophenyl)-1-(2-pyridyl)-3-dimethylaminopropane;   2-(p-bromo-alpha-(2-dimethylaminoethyl)benzyl)pyridine;   3-(4-bromophenyl)-N,N-dimethyl-3-(2-pyridinyl)-1-propanamine;   3-(p-bromophenyl)-3-(2-pyridyl)-N,N-dimethylpropylamine;   Formula=C16H19BrN2;   InChI=1S/C16H19BrN2/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13/h3-9,11,15H,10,12H2,1-2H3;   InChIKey=ZDIGNSYAACHWNL-UHFFFAOYSA-N;   SMILES=CN(C)CCC(c1ccc(Br)cc1)c1ccccn1;   [3-(4-Bromo-phenyl)-3-pyridin-2-yl-propyl]-dimethyl-amine;   bromfeniramina;   brompheniraminum
 alt_id: CHEBI:154051
 xref: Beilstein:217066 "Beilstein";   CAS:86-22-6 "ChemIDplus";   CAS:86-22-6 "KEGG COMPOUND";   CAS:86-22-6 "NIST Chemistry WebBook";   DrugBank:DB00835;   Drug_Central:408 "DrugCentral";   KEGG:C06857;   KEGG:D07543;   LINCS:LSM-1736
 xref_mesh: MESH:D001977
 xref: PMID:2570152 "ChEMBL";   PMID:2579237 "ChEMBL";   PMID:6458703 "ChEMBL";   PMID:9526560 "ChEMBL";   Patent:US2567245;   Patent:US2676964;   Wikipedia:Brompheniramine


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brompheniramine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb4 ATP binding cassette subfamily B member 4 JBrowse link 4 22,133,984 22,192,687 RGD:6480464
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:6480464
G Scn5a sodium voltage-gated channel alpha subunit 5 JBrowse link 8 128,169,191 128,266,681 RGD:6480464
G Slc22a2 solute carrier family 22 member 2 JBrowse link 1 48,318,025 48,360,219 RGD:6480464
dexbrompheniramine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:6480464
G Slc22a2 solute carrier family 22 member 2 JBrowse link 1 48,318,025 48,360,219 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19728
    role 19675
      application 19328
        pharmaceutical 19202
          drug 19202
            anti-allergic agent 3775
              brompheniramine 4
                brompheniramine maleate + 0
                dexbrompheniramine + 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19728
    subatomic particle 19724
      composite particle 19724
        hadron 19724
          baryon 19724
            nucleon 19724
              atomic nucleus 19724
                atom 19724
                  main group element atom 19610
                    p-block element atom 19610
                      carbon group element atom 19501
                        carbon atom 19494
                          organic molecular entity 19494
                            organic molecule 19417
                              organic cyclic compound 19184
                                organic heterocyclic compound 18262
                                  organic heteromonocyclic compound 16347
                                    pyridines 8327
                                      brompheniramine 4
                                        brompheniramine maleate + 0
                                        dexbrompheniramine + 2
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.