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Accession:CHEBI:31941 term browser browse the term
Definition:A platinum coordination entity that is a commonly used chemothrepeutic drug for treatment of colorectal cancer.
Synonyms:exact_synonym: (SP-4-2)[(1R,2R)-cyclohexane-1,2-diamine-kappa(2)N,N'][ethanedioato(2-)-kappa(2)O(1),O(2)]platinum
 related_synonym: (SP-4-2-(1R-trans))-(1,2-cyclohexanediamine-N,N')(ethanedioato(2-)-O,O')platinum;   Eloxatin;   Formula=C6H14N2.C2O4.Pt;   Formula=C8H14N2O4Pt;   InChI=1S/C6H14N2.C2H2O4.Pt/c7-5-3-1-2-4-6(5)8;3-1(4)2(5)6;/h5-6H,1-4,7-8H2;(H,3,4)(H,5,6);/q;;+2/p-2/t5-,6-;;/m1../s1;   InChIKey=ZROHGHOFXNOHSO-BNTLRKBRSA-L;   SMILES=[H][N]1([H])[C@@H]2CCCC[C@H]2[N]([H])([H])[Pt]11OC(=O)C(=O)O1;   oxalato(1,2-diaminocyclohexane)platinum(II);   oxaliplatine;   oxaliplatino;   oxaliplatinum
 xref: CAS:61825-94-3 "KEGG COMPOUND";   CAS:63121-00-6 "ChemIDplus";   DrugBank:DB00526;   Gmelin:1046012 "Gmelin";   Gmelin:28892 "Gmelin";   KEGG:D01790;   LINCS:LSM-6352
 xref_mesh: MESH:C030110
 xref: PMID:11300320 "Europe PMC";   PMID:14755010 "Europe PMC";   PMID:15477639 "Europe PMC";   PMID:17347561 "Europe PMC";   PMID:18440088 "Europe PMC";   PMID:19138416 "Europe PMC";   PMID:19735649 "Europe PMC";   PMID:27756654 "Europe PMC";   PMID:28186109 "Europe PMC";   PMID:28398406 "Europe PMC";   PMID:28415810 "Europe PMC";   PMID:28499428 "Europe PMC";   PMID:28505615 "Europe PMC";   PMID:28624791 "Europe PMC";   PMID:28642473 "Europe PMC";   PMID:28654098 "Europe PMC";   PMID:28695397 "Europe PMC";   PMID:28762171 "Europe PMC";   PMID:28777427 "Europe PMC";   PMID:28800641 "Europe PMC";   PMID:28811232 "Europe PMC";   PMID:28812173 "Europe PMC";   PMID:28837658 "Europe PMC";   PMID:28876454 "Europe PMC";   PMID:28881354 "Europe PMC";   PMID:28881481 "Europe PMC";   PMID:28884286 "Europe PMC";   PMID:28894576 "Europe PMC";   PMID:28924870 "Europe PMC";   PMID:28938919 "Europe PMC";   Reaxys:15700099 "Reaxys";   Wikipedia:Oxaliplatin

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  CHEBI ontology 23754
    role 23643
      biological role 23606
        aetiopathogenetic role 22199
          genotoxin 17253
            mutagen 16794
              oxaliplatin 2583
                cucurbit[7]uril--oxaliplatin 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 23754
    subatomic particle 23703
      composite particle 23703
        hadron 23703
          baryon 23703
            nucleon 23703
              atomic nucleus 23703
                atom 23703
                  metal atom 19126
                    transition element atom 18245
                      d-block element atom 18233
                        nickel group element atom 11039
                          platinum 9084
                            platinum molecular entity 9084
                              platinum coordination entity 9084
                                oxaliplatin 2583
                                  cucurbit[7]uril--oxaliplatin 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.