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ONTOLOGY REPORT - ANNOTATIONS


Term:buclizine
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Accession:CHEBI:3205 term browser browse the term
Definition:An N-alkylpiperazine carrying (4-chlorophenyl)(phenyl)methyl and 4-tert-butylbenzyl groups.
Synonyms:exact_synonym: 1-(4-tert-butylbenzyl)-4-[(4-chlorophenyl)(phenyl)methyl]piperazine
 related_synonym: 1-(p-tert-Butylbenzyl)-4-(4-chloro-alpha-phenylbenzyl)piperazine;   Formula=C28H33ClN2;   InChI=1S/C28H33ClN2/c1-28(2,3)25-13-9-22(10-14-25)21-30-17-19-31(20-18-30)27(23-7-5-4-6-8-23)24-11-15-26(29)16-12-24/h4-16,27H,17-21H2,1-3H3;   InChIKey=MOYGZHXDRJNJEP-UHFFFAOYSA-N;   SMILES=CC(C)(C)c1ccc(CN2CCN(CC2)C(c2ccccc2)c2ccc(Cl)cc2)cc1;   buclizina;   buclizinum
 xref: Beilstein:349567;   CAS:82-95-1;   DrugBank:DB00354;   Drug_Central:416;   HMDB:HMDB0014498;   KEGG:C07777;   KEGG:D07547
 xref_mesh: MESH:C046894
 xref: PMID:13620483;   PMID:14428806;   PMID:22469258;   PMID:4387177;   PMID:5304814;   Patent:GB1311286;   Patent:US2709169;   Reaxys:349567;   Wikipedia:Buclizine
 cyclic_relationship: is_conjugate_base_of CHEBI:61192


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buclizine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19770
    role 19717
      biological role 19716
        pharmacological role 18801
          antagonist 16206
            histamine antagonist 4603
              buclizine 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19770
    subatomic particle 19768
      composite particle 19768
        hadron 19768
          baryon 19768
            nucleon 19768
              atomic nucleus 19768
                atom 19768
                  main group element atom 19655
                    main group molecular entity 19655
                      s-block molecular entity 19398
                        hydrogen molecular entity 19388
                          hydrides 18363
                            inorganic hydride 17213
                              pnictogen hydride 17176
                                nitrogen hydride 17011
                                  azane 16704
                                    ammonia 16703
                                      organic amino compound 16702
                                        tertiary amino compound 8625
                                          N-alkylpiperazine 3051
                                            buclizine 1
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