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ONTOLOGY REPORT - ANNOTATIONS


Term:saccharin
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Accession:CHEBI:32111 term browser browse the term
Definition:A 1,2-benzisothiazole having a keto-group at the 3-position and two oxo substituents at the 1-position. It is used as an artificial sweetening agent.
Synonyms:related_synonym: 1,1-Dioxo-1,2-benzisothiazol-3(2H)-one;   1,1-Dioxo-1,2-dihydro-benzo[d]isothiazol-3-one;   1,2-Benzisothiazol-3(2H)-one 1,1-dioxide;   1,2-Benzisothiazolin-3-one 1,1-dioxide;   1,2-Dihydro-2-ketobenzisosulfonazole;   1,2-Dihydro-2-ketobenzisosulphonazole;   2,3-Dihydro-3-oxobenzisosulfonazole;   2,3-Dihydro-3-oxobenzisosulphonazole;   3-Hydroxybenzisothiazole-S,S-dioxide;   Anhydro-o-sulfaminebenzoic acid;   Benzo-2-sulphimide;   Benzoic acid sulfimide;   Benzoic sulfimide;   Benzoic sulphimide;   Benzosulfimide;   Benzosulphimide;   Benzoylsulfonic Imide;   Formula=C7H5NO3S;   InChI=1S/C7H5NO3S/c9-7-5-3-1-2-4-6(5)12(10,11)8-7/h1-4H,(H,8,9);   InChIKey=CVHZOJJKTDOEJC-UHFFFAOYSA-N;   SMILES=O=C1NS(=O)(=O)c2ccccc12;   Saccharimide;   Saccharine;   o-Benzoic sulfimide;   o-Benzosulfimide;   o-Sulfobenzimide;   o-Sulfobenzoic acid imide
 alt_id: CHEBI:49717
 xref: Beilstein:6888 "Beilstein";   CAS:81-07-2 "ChemIDplus";   CAS:81-07-2 "KEGG DRUG";   CAS:81-07-2 "NIST Chemistry WebBook";   Gmelin:4203 "Gmelin";   HMDB:HMDB0029723;   KEGG:D01085
 xref_mesh: MESH:D012439
 xref: MetaCyc:CPD-5581;   PDBeChem:LSA;   PMID:24456165 "Europe PMC";   PMID:24549104 "Europe PMC";   PMID:24739358 "Europe PMC";   PMID:24780866 "Europe PMC";   Reaxys:6888 "Reaxys";   Wikipedia:Saccharin


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saccharin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Afp alpha-fetoprotein JBrowse link 14 19,141,755 19,159,919 RGD:6480464
G Ca13 carbonic anhydrase 13 JBrowse link 2 88,282,961 88,314,254 RGD:6480464
G Ca3 carbonic anhydrase 3 JBrowse link 2 88,126,519 88,136,063 RGD:6480464
G Cdk1 cyclin-dependent kinase 1 JBrowse link 20 20,576,341 20,591,510 RGD:6480464
G Cer1 cerberus 1, DAN family BMP antagonist JBrowse link 5 101,003,019 101,006,375 RGD:6480464
G Chek1 checkpoint kinase 1 JBrowse link 8 39,181,162 39,201,588 RGD:6480464
G Fosl1 FOS like 1, AP-1 transcription factor subunit JBrowse link 1 220,826,560 220,835,066 RGD:6480464
G Gnat3 G protein subunit alpha transducin 3 JBrowse link 4 13,827,764 13,878,126 RGD:6480464
G Hdac7 histone deacetylase 7 JBrowse link 7 139,280,396 139,319,108 RGD:6480464
G Hells helicase, lymphoid specific JBrowse link 1 257,901,856 257,953,889 RGD:6480464
G Il1rl1 interleukin 1 receptor-like 1 JBrowse link 9 47,133,483 47,184,316 RGD:6480464
G Jun Jun proto-oncogene, AP-1 transcription factor subunit JBrowse link 5 114,011,184 114,014,277 RGD:6480464
G Junb JunB proto-oncogene, AP-1 transcription factor subunit JBrowse link 19 26,092,972 26,094,756 RGD:6480464
G Kdr kinase insert domain receptor JBrowse link 14 34,727,677 34,787,127 RGD:6480464
G Mcm3 minichromosome maintenance complex component 3 JBrowse link 9 26,914,057 26,932,201 RGD:6480464
G Mesp1 mesoderm posterior bHLH transcription factor 1 JBrowse link 1 141,532,390 141,533,908 RGD:6480464
G Myc MYC proto-oncogene, bHLH transcription factor JBrowse link 7 102,586,313 102,591,240 RGD:6480464
G Myo1e myosin IE JBrowse link 8 76,644,715 76,840,240 RGD:6480464
G Nes nestin JBrowse link 2 187,343,109 187,352,972 RGD:6480464
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:6480464
G Nup54 nucleoporin 54 JBrowse link 14 17,123,434 17,141,832 RGD:6480464
G Orm1 orosomucoid 1 JBrowse link 5 79,179,668 79,182,820 RGD:6480464
G Phex phosphate regulating endopeptidase homolog, X-linked JBrowse link X 40,460,047 40,717,982 RGD:6480464
G Pik3r5 phosphoinositide-3-kinase, regulatory subunit 5 JBrowse link 10 55,013,686 55,078,986 RGD:6480464
G Pnpla6 patatin-like phospholipase domain containing 6 JBrowse link 12 2,068,749 2,098,139 RGD:6480464
G Ppara peroxisome proliferator activated receptor alpha JBrowse link 7 126,618,872 126,687,282 RGD:6480464
G Rad21 RAD21 cohesin complex component JBrowse link 7 91,511,755 91,538,673 RGD:6480464
G Rif1 replication timing regulatory factor 1 JBrowse link 3 37,599,540 37,648,818 RGD:6480464
G Scarb1 scavenger receptor class B, member 1 JBrowse link 12 36,694,952 36,761,445 RGD:6480464
G Shh sonic hedgehog signaling molecule JBrowse link 4 718,538 727,691 RGD:6480464
G Slc2a1 solute carrier family 2 member 1 JBrowse link 5 138,154,677 138,182,897 RGD:6480464
G Stmn1 stathmin 1 JBrowse link 5 152,680,412 152,686,807 RGD:6480464
G Tas1r3 taste 1 receptor member 3 JBrowse link 5 173,307,325 173,312,950 RGD:6480464
G Tas2r136 taste receptor, type 2, member 136 JBrowse link 4 166,978,399 166,979,391 RGD:6480464
G Tfrc transferrin receptor JBrowse link 11 71,397,423 71,419,263 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 JBrowse link 10 59,799,123 59,824,208 RGD:6480464
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:6480464
G Wnt3 Wnt family member 3 JBrowse link 10 91,830,709 91,874,907 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19654
    role 19598
      biological role 19596
        xenobiotic 18165
          saccharin 39
            probenazole 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19654
    subatomic particle 19650
      composite particle 19650
        hadron 19650
          baryon 19650
            nucleon 19650
              atomic nucleus 19650
                atom 19650
                  main group element atom 19531
                    p-block element atom 19531
                      carbon group element atom 19413
                        carbon atom 19405
                          organic molecular entity 19405
                            organic molecule 19327
                              organic cyclic compound 19076
                                organic heterocyclic compound 18151
                                  organic heteropolycyclic compound 17415
                                    organic heterobicyclic compound 15891
                                      benzothiazoles 130
                                        1,2-benzisothiazole 47
                                          saccharin 39
                                            probenazole 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.