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ONTOLOGY REPORT - ANNOTATIONS


Term:bupivacaine
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Accession:CHEBI:3215 term browser browse the term
Definition:A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.
Synonyms:exact_synonym: rac-1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
 related_synonym: (RS)-bupivacaine;   1-Butyl-2',6'-pipecoloxylidide;   1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide;   Carbostesin;   DL-Bupivacaine;   Formula=C18H28N2O;   bupivacaina;   bupivacainum;   dl-1-Butyl-2',6'-pipecoloxylidide;   racemic bupivacaine
 alt_id: CHEBI:250882
 xref: CAS:2180-92-9 "KEGG COMPOUND";   CAS:2180-92-9 "NIST Chemistry WebBook";   CAS:38396-39-3 "ChemIDplus";   CAS:38396-39-3 "KEGG COMPOUND";   DrugBank:DB00297;   HMDB:HMDB0014442;   KEGG:C07529;   KEGG:D07552
 xref_mesh: MESH:D002045
 xref: PMID:10211016 "Europe PMC";   PMID:10499757 "Europe PMC";   PMID:11018648 "Europe PMC";   PMID:11020763 "Europe PMC";   PMID:11412729 "Europe PMC";   PMID:11529341 "Europe PMC";   PMID:11759364 "Europe PMC";   PMID:11778087 "Europe PMC";   PMID:11801199 "Europe PMC";   PMID:11812691 "Europe PMC";   PMID:14980918 "Europe PMC";   PMID:15321223 "Europe PMC";   PMID:16037174 "Europe PMC";   PMID:16418020 "Europe PMC";   PMID:17134470 "Europe PMC";   PMID:18299091 "Europe PMC";   PMID:18420860 "Europe PMC";   PMID:18451389 "Europe PMC";   PMID:18940244 "Europe PMC";   PMID:19468619 "Europe PMC";   PMID:19800297 "Europe PMC";   PMID:20164497 "Europe PMC";   PMID:23446090 "Europe PMC";   PMID:23807278 "Europe PMC";   PMID:23925646 "Europe PMC";   PMID:23978626 "Europe PMC";   PMID:24117122 "Europe PMC";   PMID:24117225 "Europe PMC";   PMID:24200700 "Europe PMC";   PMID:24317184 "Europe PMC";   PMID:24393760 "Europe PMC";   PMID:24398818 "Europe PMC";   PMID:24445889 "Europe PMC";   PMID:24450503 "Europe PMC";   PMID:24476569 "Europe PMC";   PMID:24513957 "Europe PMC";   PMID:24532522 "Europe PMC";   PMID:24535791 "Europe PMC";   PMID:8368547 "Europe PMC";   PMID:8489063 "Europe PMC";   PMID:9209608 "Europe PMC";   PMID:9989796 "Europe PMC";   Patent:US2955111;   Reaxys:280794 "Reaxys";   Wikipedia:Bupivacaine
 cyclic_relationship: is_conjugate_base_of CHEBI:77455


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bupivacaine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Casp9 caspase 9 JBrowse link 5 160,356,211 160,373,774 RGD:6480464
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 JBrowse link 12 19,074,288 19,114,491 RGD:6480464
G Entpd4 ectonucleoside triphosphate diphosphohydrolase 4 JBrowse link 15 51,222,954 51,250,787 RGD:6480464
G Hpgds hematopoietic prostaglandin D synthase JBrowse link 4 95,945,356 95,970,666 RGD:6480464
G Itgam integrin subunit alpha M JBrowse link 1 199,495,312 199,545,738 RGD:6480464
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 JBrowse link 11 32,498,260 32,511,202 RGD:6480464
G Kcnk9 potassium two pore domain channel subfamily K member 9 JBrowse link 7 113,894,918 113,938,397 RGD:6480464
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 JBrowse link 1 216,293,087 216,630,339 RGD:6480464
G Myf5 myogenic factor 5 JBrowse link 7 49,729,533 49,732,974 RGD:6480464
G Myod1 myogenic differentiation 1 JBrowse link 1 102,396,538 102,399,248 RGD:6480464
G Myog myogenin JBrowse link 13 51,126,459 51,129,048 RGD:6480464
G Prkcb protein kinase C, beta JBrowse link 1 192,233,569 192,575,339 RGD:6480464
G Ptgdr prostaglandin D2 receptor JBrowse link 15 19,195,606 19,196,508 RGD:6480464
G Ptgs1 prostaglandin-endoperoxide synthase 1 JBrowse link 3 15,560,685 15,582,339 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:6480464
G Slc6a2 solute carrier family 6 member 2 JBrowse link 19 15,391,682 15,431,274 RGD:6480464
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 JBrowse link 10 59,799,123 59,824,208 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19748
    chemical entity 19746
      chemical substance 11490
        mixture 10810
          racemate 9688
            bupivacaine 18
Path 2
Term Annotations click to browse term
  CHEBI ontology 19748
    subatomic particle 19744
      composite particle 19744
        hadron 19744
          baryon 19744
            nucleon 19744
              atomic nucleus 19744
                atom 19744
                  main group element atom 19628
                    p-block element atom 19628
                      carbon group element atom 19522
                        carbon atom 19516
                          organic molecular entity 19516
                            organic group 18426
                              organic divalent group 18418
                                organodiyl group 18418
                                  carbonyl group 18306
                                    carbonyl compound 18306
                                      carboxylic acid 17973
                                        carboacyl group 17082
                                          univalent carboacyl group 17082
                                            carbamoyl group 16811
                                              carboxamide 16811
                                                monocarboxylic acid amide 14170
                                                  piperidinecarboxamide 27
                                                    1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide 18
                                                      dextrobupivacaine 18
                                                        bupivacaine 18
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.