Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:suxibuzone
go back to main search page
Accession:CHEBI:32173 term browser browse the term
Definition:A pyrazolidine that is phenylbutazone which is substituted by a 3-carboxypropanoylmethyl group at the 4-position. Suxibuzone is a prodrug for phenylbutazone and is commonly used as an anti-inflammatory drug in horses.
Synonyms:exact_synonym: 4-[(4-butyl-3,5-dioxo-1,2-diphenylpyrazolidin-4-yl)methoxy]-4-oxobutanoic acid
 related_synonym: 4-Butyl-4-hydroxymethyl-1,2-diphenyl-3,5-pyrazolidinedione hydrogen succinate;   4-Hydroxymethylbutazolidine hemisuccinate;   Formula=C24H26N2O6;   InChI=1S/C24H26N2O6/c1-2-3-16-24(17-32-21(29)15-14-20(27)28)22(30)25(18-10-6-4-7-11-18)26(23(24)31)19-12-8-5-9-13-19/h4-13H,2-3,14-17H2,1H3,(H,27,28);   InChIKey=ONWXNHPOAGOMTG-UHFFFAOYSA-N;   SMILES=CCCCC1(COC(=O)CCC(O)=O)C(=O)N(N(C1=O)c1ccccc1)c1ccccc1;   suxibuzona;   suxibuzonum
 xref: AGR:IND44395503 "Europe PMC";   Beilstein:904563 "Beilstein";   CAS:27470-51-5 "ChemIDplus";   CAS:27470-51-5 "KEGG DRUG";   Drug_Central:2547 "DrugCentral";   HMDB:HMDB0042019;   KEGG:D01289;   LINCS:LSM-5851
 xref_mesh: MESH:C003371
 xref: PMID:10505957 "Europe PMC";   PMID:19927590 "Europe PMC";   PMID:20037965 "Europe PMC";   PMID:3425858 "Europe PMC";   PMID:6345427 "Europe PMC";   PMID:7097505 "Europe PMC";   PMID:7452452 "Europe PMC";   PMID:8230399 "Europe PMC";   Reaxys:904563 "Reaxys";   VSDB:1815;   Wikipedia:Suxibuzone


show annotations for term's descendants       view all columns           Sort by:
 
suxibuzone term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pklr pyruvate kinase L/R JBrowse link 2 188,449,158 188,458,034 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19728
    role 19675
      application 19328
        pro-agent 8807
          prodrug 8597
            suxibuzone 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19728
    subatomic particle 19724
      composite particle 19724
        hadron 19724
          baryon 19724
            nucleon 19724
              atomic nucleus 19724
                atom 19724
                  main group element atom 19610
                    p-block element atom 19610
                      carbon group element atom 19501
                        carbon atom 19494
                          organic molecular entity 19494
                            organic group 18413
                              organic divalent group 18404
                                organodiyl group 18404
                                  carbonyl group 18293
                                    carbonyl compound 18293
                                      dicarboxylic acids and O-substituted derivatives 10203
                                        dicarboxylic acid 10197
                                          alpha,omega-dicarboxylic acid 2746
                                            succinic acid 206
                                              succinate ester 96
                                                hemisuccinate 92
                                                  suxibuzone 1
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.