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Accession:CHEBI:32269 term browser browse the term
Definition:An indolyl carboxylate ester obtained by formal condensation of the carboxy group of indole-3-carboxylic acid with the hydroxy group of tropine.
Synonyms:exact_synonym: (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl 1H-indole-3-carboxylate
 related_synonym: 1alphaH,5alphaH-Tropan-3alpha-yl indole-3-carboxylate;   Formula=C17H20N2O2;   InChI=1S/C17H20N2O2/c1-19-11-6-7-12(19)9-13(8-11)21-17(20)15-10-18-16-5-3-2-4-14(15)16/h2-5,10-13,18H,6-9H2,1H3/t11-,12+,13+;   InChIKey=ZNRGQMMCGHDTEI-ITGUQSILSA-N;   SMILES=CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)c1c[nH]c2ccccc12;   tropisetronum
 xref: CAS:89565-68-4 "ChemIDplus";   CAS:89565-68-4 "KEGG COMPOUND";   Drug_Central:2775 "DrugCentral";   KEGG:C13666;   KEGG:D02130
 xref_mesh: MESH:C045504
 xref: PDBeChem:TKT;   PMID:22905891 "Europe PMC";   PMID:23135693 "Europe PMC";   PMID:23415734 "Europe PMC";   PMID:23440693 "Europe PMC";   PMID:23515583 "Europe PMC";   PMID:23717236 "Europe PMC";   PMID:23727438 "Europe PMC";   PMID:23774631 "Europe PMC";   PMID:23868810 "Europe PMC";   PMID:23896722 "Europe PMC";   PMID:23937291 "Europe PMC";   PMID:24226381 "Europe PMC";   PMID:24374478 "Europe PMC";   PMID:24389031 "Europe PMC";   PMID:24455480 "Europe PMC";   PMID:24461640 "Europe PMC";   Reaxys:3619989 "Reaxys";   Wikipedia:Tropisetron
 cyclic_relationship: is_conjugate_base_of CHEBI:77571

show annotations for term's descendants       view all columns           Sort by:
tropisetron term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccl3 C-C motif chemokine ligand 3 JBrowse link 10 70,869,516 70,871,066 RGD:6480464
G Cxcl1 C-X-C motif chemokine ligand 1 JBrowse link 14 18,743,678 18,745,457 RGD:6480464
G Cxcl2 C-X-C motif chemokine ligand 2 JBrowse link 14 18,731,346 18,733,391 RGD:6480464
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:6480464
G Icam1 intercellular adhesion molecule 1 JBrowse link 8 22,035,287 22,047,049 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Il2 interleukin 2 JBrowse link 2 123,847,150 123,851,854 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Mpo myeloperoxidase JBrowse link 10 75,087,892 75,098,260 RGD:6480464
G Slc22a2 solute carrier family 22 member 2 JBrowse link 1 48,318,025 48,360,219 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19734
    role 19680
      biological role 19678
        immunomodulator 13674
          tropisetron 11
Path 2
Term Annotations click to browse term
  CHEBI ontology 19734
    subatomic particle 19730
      composite particle 19730
        hadron 19730
          baryon 19730
            nucleon 19730
              atomic nucleus 19730
                atom 19730
                  main group element atom 19614
                    p-block element atom 19614
                      carbon group element atom 19506
                        carbon atom 19500
                          organic molecular entity 19500
                            organic molecule 19418
                              organic cyclic compound 19189
                                organic heterocyclic compound 18267
                                  organic heteropolycyclic compound 17572
                                    organic heterobicyclic compound 16245
                                      benzopyrrole 9336
                                        indoles 9198
                                          indolyl carboxylic acid 3169
                                            indol-3-yl carboxylic acid 3168
                                              indole-3-carboxylic acid 12
                                                tropisetron 11
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.