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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:32347 term browser browse the term
Definition:A biguanide that has formula C8H10ClN5.
Synonyms:related_synonym: Formula=C8H10ClN5;   InChI=1S/C8H10ClN5/c9-5-2-1-3-6(4-5)13-8(12)14-7(10)11/h1-4H,(H6,10,11,12,13,14);   InChIKey=DIHXJZHAIHGSAW-UHFFFAOYSA-N;   SMILES=NC(=N)NC(=N)Nc1cccc(Cl)c1;   mCPBG
 xref: CAS:48144-44-1;   KEGG:C13646;   LINCS:LSM-2812
 xref_mesh: MESH:C065734

show annotations for term's descendants           Sort by:
m-Chlorophenylbiguanide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP 1-(3-chlorophenyl)biguanide results in increased expression of FOS protein CTD PMID:12088752 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Htr3a 5-hydroxytryptamine receptor 3A multiple interactions
decreases expression
EXP BESEB CDRI-08 inhibits the reaction [1-(3-chlorophenyl)biguanide results in decreased expression of HTR3A mRNA] CTD PMID:21735137 NCBI chr 8:53,211,436...53,223,878
Ensembl chr 8:53,211,438...53,223,804
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19810
    role 19758
      application 19420
        pharmaceutical 19293
          drug 19293
            hypoglycemic agent 4036
              biguanides 441
                m-Chlorophenylbiguanide 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    p-block element atom 19696
                      carbon group element atom 19599
                        carbon atom 19588
                          organic molecular entity 19588
                            organic molecule 19514
                              organic cyclic compound 19311
                                carbocyclic compound 18219
                                  benzenoid aromatic compound 17254
                                    benzenes 17011
                                      chlorobenzenes 13348
                                        monochlorobenzenes 9527
                                          m-Chlorophenylbiguanide 2
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.