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ONTOLOGY REPORT - ANNOTATIONS


Term:butorphanol
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Accession:CHEBI:3242 term browser browse the term
Definition:Levorphanol in which a hydrogen at position 14 of the morphinan skeleton is substituted by hydroxy and one of the hydrogens of the N-methyl group is substituted by cyclopropyl. A semi-synthetic opioid agonist-antagonist analgesic, it is used as its (S,S)-tartaric acid salt for relief or moderate to severe pain.
Synonyms:related_synonym: (-)-17-(cyclobutylmethyl)morphinan-3,14-diol;   (-)-N-cyclobutylmethyl-3,14-dihydroxymorphinan;   Formula=C21H29NO2;   InChI=1S/C21H29NO2/c23-17-7-6-16-12-19-21(24)9-2-1-8-20(21,18(16)13-17)10-11-22(19)14-15-4-3-5-15/h6-7,13,15,19,23-24H,1-5,8-12,14H2/t19-,20+,21-/m1/s1;   InChIKey=IFKLAQQSCNILHL-QHAWAJNXSA-N;   SMILES=Oc1ccc2C[C@H]3N(CC[C@@]4(CCCC[C@@]34O)c2c1)CC1CCC1;   butorfanol;   butorphanolum
 alt_id: CHEBI:145838
 xref: Beilstein:8134188 "Beilstein";   CAS:42408-82-2 "ChemIDplus";   CAS:42408-82-2 "KEGG COMPOUND";   DrugBank:DB00611;   Drug_Central:454 "DrugCentral";   KEGG:C06863;   KEGG:D03197
 xref_mesh: MESH:D002077
 xref: PMID:6114178 "ChEMBL";   PMID:6166748 "ChEMBL";   PMID:6767032 "ChEMBL";   PMID:6796691 "ChEMBL";   PMID:7192744 "ChEMBL";   Patent:DE2243961;   Patent:US3775414;   Patent:US3819635;   VSDB:1780;   Wikipedia:Butorphanol


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butorphanol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Oprd1 opioid receptor, delta 1 JBrowse link 5 150,288,126 150,323,063 RGD:6480464
G Oprk1 opioid receptor, kappa 1 JBrowse link 5 13,742,655 13,760,460 RGD:6480464
G Oprm1 opioid receptor, mu 1 JBrowse link 1 43,454,803 43,704,948 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19764
    role 19711
      application 19362
        pharmaceutical 19231
          drug 19231
            antitussive 226
              butorphanol 3
                butorphanol D-tartrate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19764
    subatomic particle 19762
      composite particle 19762
        hadron 19762
          baryon 19762
            nucleon 19762
              atomic nucleus 19762
                atom 19762
                  main group element atom 19646
                    p-block element atom 19646
                      carbon group element atom 19540
                        carbon atom 19529
                          organic molecular entity 19529
                            heteroorganic entity 19106
                              organonitrogen compound 18203
                                alkaloid 5287
                                  isoquinoline alkaloid 1126
                                    morphinane alkaloid 657
                                      butorphanol 3
                                        butorphanol D-tartrate 0
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