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ONTOLOGY REPORT - ANNOTATIONS


Term:calcein am
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Accession:CHEBI:3303 term browser browse the term
Definition:An organic heteropentacyclic compound that is calcein in which all four carboxy group hydrogens have been substituted by (acetyloxy)methoxy groups and the hyrodgens of the two hydroxy groups have been substituted by acetyl groups. It is a a non-fluorescent probe cleaved to a fluorescent probe by non-specific intracellular esterases.
Synonyms:exact_synonym: tetrakis[(acetyloxy)methyl] 2,2',2'',2'''-{[3',6'-bis(acetyloxy)-3-oxo-3H-spiro[[2]benzofuran-1,9'-xanthene]-2',7'-diyl]bis(methanediylnitrilo)}tetraacetate
 related_synonym: Formula=C46H46N2O23;   InChI=1S/C46H46N2O23/c1-25(49)60-21-64-41(55)17-47(18-42(56)65-22-61-26(2)50)15-31-11-35-39(13-37(31)68-29(5)53)70-40-14-38(69-30(6)54)32(12-36(40)46(35)34-10-8-7-9-33(34)45(59)71-46)16-48(19-43(57)66-23-62-27(3)51)20-44(58)67-24-63-28(4)52/h7-14H,15-24H2,1-6H3;   InChIKey=BQRGNLJZBFXNCZ-UHFFFAOYSA-N;   SMILES=O(C1=C(C=C2C3(OC(C4=C3C=CC=C4)=O)C=5C(OC2=C1)=CC(=C(C5)CN(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)OC(C)=O)CN(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)C(C)=O;   [({[3',6'-bis(acetyloxy)-3-oxo-3H-spiro[[2]benzofuran-1,9'-xanthene]-2',7'-diyl]bis(methylene)nitrilo}bis[(1-oxoethane-2,1-diyl)oxy]methylene)] tetraacetate;   calcein O,O'-diacetate tetrakis(acetoxymethyl) ester
 alt_id: CHEBI:51904
 xref: CAS:148504-34-1 "ChemIDplus";   CAS:148504-34-1 "KEGG COMPOUND";   KEGG:C11257
 xref_mesh: MESH:C085925
 xref: PMID:30925062 "Europe PMC";   PMID:31188648 "Europe PMC";   PMID:31489142 "Europe PMC";   PMID:8107502 "Europe PMC"


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Path 1
Term Annotations click to browse term
  CHEBI ontology 0
    role 0
      application 0
        dye 0
          xanthene dye 0
            calcein am 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 0
    subatomic particle 0
      composite particle 0
        hadron 0
          baryon 0
            nucleon 0
              atomic nucleus 0
                atom 0
                  main group element atom 0
                    p-block element atom 0
                      carbon group element atom 0
                        carbon atom 0
                          organic molecular entity 0
                            organic group 0
                              organic divalent group 0
                                organodiyl group 0
                                  carbonyl group 0
                                    carbonyl compound 0
                                      carboxylic acid 0
                                        monocarboxylic acid 0
                                          acetic acid 0
                                            acetate ester 0
                                              calcein am 0
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