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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:acenaphthylene
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Accession:CHEBI:33081 term browser browse the term
Definition:A ortho- and peri-fused tricyclic hydrocarbon that occurs in coal tar.
Synonyms:related_synonym: Formula=C12H8;   InChI=1S/C12H8/c1-3-9-4-2-6-11-8-7-10(5-1)12(9)11/h1-8H;   InChIKey=HXGDTGSAIMULJN-UHFFFAOYSA-N;   SMILES=c1cc2C=Cc3cccc(c1)c23;   cyclopenta[de]naphthalene
 xref: Beilstein:774092;   CAS:208-96-8;   Gmelin:102938
 xref_mesh: MESH:C042553
 xref: PMID:17824537;   PMID:24631927;   Reaxys:774092;   Wikipedia:Acenaphthylene


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acenaphthylene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression EXP acenaphthylene results in increased expression of CYP1A1 mRNA; acenaphthylene results in increased expression of CYP1A1 protein CTD PMID:10190573 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression
increases oxidation
increases activity
multiple interactions
ISO acenaphthylene results in increased expression of CYP1A2 mRNA; acenaphthylene results in increased expression of CYP1A2 protein
CYP1A2 protein results in increased oxidation of acenaphthylene
acenaphthylene results in increased activity of CYP1A2 protein
[acenaphthylene co-treated with acenaphthene co-treated with dibenzofuran co-treated with fluorene co-treated with phenanthrene co-treated with anthracene] results in increased expression of CYP1A2 mRNA
CTD PMID:7750161, PMID:8001243, PMID:10977129, PMID:25642975 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression
increases oxidation
ISO acenaphthylene results in increased expression of CYP1B1 mRNA
CYP1B1 protein results in increased oxidation of acenaphthylene
CTD PMID:10402558, PMID:25642975 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO acenaphthylene results in increased cleavage of PARP1 protein CTD PMID:21132278 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19816
    role 19764
      biological role 19764
        aetiopathogenetic role 18960
          carcinogenic agent 18331
            polycyclic arene 16889
              ortho- and peri-fused polycyclic arene 16155
                acenaphthylene 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19816
    subatomic particle 19814
      composite particle 19814
        hadron 19814
          baryon 19814
            nucleon 19814
              atomic nucleus 19814
                atom 19814
                  main group element atom 19702
                    main group molecular entity 19702
                      s-block molecular entity 19461
                        hydrogen molecular entity 19452
                          hydrides 18707
                            organic hydride 18269
                              organic fundamental parent 18269
                                hydrocarbon 17988
                                  cyclic hydrocarbon 17075
                                    arene 17071
                                      polycyclic arene 16889
                                        ortho- and peri-fused polycyclic arene 16155
                                          acenaphthylene 4
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