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ONTOLOGY REPORT - ANNOTATIONS


Term:adrenaline
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Accession:CHEBI:33568 term browser browse the term
Definition:A catecholamine in which the aminoethyl side-chain is hydroxy-substituted at C-1 and methylated on nitrogen.
Synonyms:exact_synonym: 4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol
 related_synonym: (+-)-epinephrine;   2-(methylamino)-1-(3,4-dihydroxyphenyl)ethanol;   Formula=C9H13NO3;   InChI=1S/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H3;   InChIKey=UCTWMZQNUQWSLP-UHFFFAOYSA-N;   SMILES=CNCC(O)c1ccc(O)c(O)c1;   dl-adrenaline;   epinephrine racemic;   racepinefrina;   racepinefrine;   racepinefrinum
 xref: Beilstein:2212160 "ChemIDplus";   CAS:329-65-7 "ChemIDplus";   Drug_Central:4508 "DrugCentral";   Gmelin:51559 "Gmelin";   LINCS:LSM-4958;   PMID:10052027 "Europe PMC";   PMID:24252294 "Europe PMC";   PMID:24719616 "Europe PMC";   Reaxys:2212160 "Reaxys"


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(R)-adrenaline term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcc1 ATP binding cassette subfamily C member 1 JBrowse link 10 549,537 672,235 RGD:6480464
G Aco2 aconitase 2 JBrowse link 7 123,102,493 123,145,608 RGD:6480464
G Actn1 actinin, alpha 1 JBrowse link 6 103,376,557 103,470,497 RGD:6480464
G Adra1a adrenoceptor alpha 1A JBrowse link 15 43,296,997 43,398,314 RGD:6480464
G Adra1b adrenoceptor alpha 1B JBrowse link 10 29,392,762 29,450,644 RGD:6480464
G Adra1d adrenoceptor alpha 1D JBrowse link 3 124,129,558 124,145,566 RGD:6480464
G Adra2a adrenoceptor alpha 2A JBrowse link 1 274,766,283 274,769,083 RGD:6480464
G Adra2b adrenoceptor alpha 2B JBrowse link 3 119,805,941 119,809,987 RGD:6480464
G Adra2c adrenoceptor alpha 2C JBrowse link 14 80,730,307 80,732,010 RGD:6480464
G Adrb1 adrenoceptor beta 1 JBrowse link 1 277,537,585 277,538,985 RGD:6480464
G Adrb2 adrenoceptor beta 2 JBrowse link 18 57,513,792 57,515,834 RGD:6480464
G Adrb3 adrenoceptor beta 3 JBrowse link 16 69,003,541 69,006,632 RGD:6480464
G Ak2 adenylate kinase 2 JBrowse link 5 147,185,474 147,204,050 RGD:6480464
G Aoc1 amine oxidase, copper containing 1 JBrowse link 4 78,496,043 78,515,582 RGD:6480464
G Aqp7 aquaporin 7 JBrowse link 5 57,358,297 57,372,332 RGD:6480464
G Atp5f1a ATP synthase F1 subunit alpha JBrowse link 18 74,156,553 74,164,490 RGD:6480464
G C1qbp complement C1q binding protein JBrowse link 10 57,613,876 57,618,527 RGD:6480464
G Calca calcitonin-related polypeptide alpha JBrowse link 1 184,184,018 184,188,922 RGD:6480464
G Caly calcyon neuron-specific vesicular protein JBrowse link 1 212,537,851 212,549,040 RGD:6480464
G Car2 carbonic anhydrase 2 JBrowse link 2 88,097,740 88,112,868 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:6480464
G Ccl3 C-C motif chemokine ligand 3 JBrowse link 10 70,869,516 70,871,066 RGD:6480464
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:6480464
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit JBrowse link 1 123,897,341 124,039,263 RGD:6480464
G Comt catechol-O-methyltransferase JBrowse link 11 86,715,981 86,735,630 RGD:6480464
G Creb1 cAMP responsive element binding protein 1 JBrowse link 9 71,229,753 71,298,994 RGD:6480464
G Crh corticotropin releasing hormone JBrowse link 2 104,459,999 104,461,863 RGD:6480464
G Csk C-terminal Src kinase JBrowse link 8 62,405,714 62,424,707 RGD:6480464
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:6480464
G Ctsk cathepsin K JBrowse link 2 196,655,469 196,666,447 RGD:6480464
G Cycs cytochrome c, somatic JBrowse link 4 80,331,226 80,333,326 RGD:6480464
G Dbh dopamine beta-hydroxylase JBrowse link 3 5,709,236 5,731,895 RGD:6480464
G Des desmin JBrowse link 9 82,556,574 82,564,288 RGD:6480464
G Dlat dihydrolipoamide S-acetyltransferase JBrowse link 8 55,062,549 55,087,832 RGD:6480464
G Echs1 enoyl-CoA hydratase, short chain 1 JBrowse link 1 212,570,213 212,579,040 RGD:6480464
G Epha4 Eph receptor A4 JBrowse link 9 83,111,222 83,253,486 RGD:6480464
G Etfb electron transfer flavoprotein subunit beta JBrowse link 1 98,472,776 98,486,940 RGD:6480464
G Fabp3 fatty acid binding protein 3 JBrowse link 5 148,528,854 148,535,597 RGD:6480464
G Fas Fas cell surface death receptor JBrowse link 1 252,589,785 252,624,790 RGD:6480464
G Faslg Fas ligand JBrowse link 13 79,696,811 79,717,581 RGD:6480464
G Fh fumarate hydratase JBrowse link 13 93,651,486 93,677,371 RGD:6480464
G Gnb2 G protein subunit beta 2 JBrowse link 12 22,229,079 22,234,096 RGD:6480464
G Gnb4 G protein subunit beta 4 JBrowse link 2 118,978,965 119,007,877 RGD:6480464
G Gng12 G protein subunit gamma 12 JBrowse link 4 97,634,925 97,763,478 RGD:6480464
G Gng2 G protein subunit gamma 2 JBrowse link 15 4,748,242 4,853,555 RGD:6480464
G Gng3 G protein subunit gamma 3 JBrowse link 1 225,033,921 225,035,687 RGD:6480464
G Gng4 G protein subunit gamma 4 JBrowse link 17 90,266,571 90,316,278 RGD:6480464
G Grk2 G protein-coupled receptor kinase 2 JBrowse link 1 219,536,220 219,544,329 RGD:6480464
G Grk5 G protein-coupled receptor kinase 5 JBrowse link 1 282,265,371 282,467,842 RGD:6480464
G Hadh hydroxyacyl-CoA dehydrogenase JBrowse link 2 236,353,445 236,395,067 RGD:6480464
G Hsf1 heat shock transcription factor 1 JBrowse link 7 117,538,523 117,565,478 RGD:6480464
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 JBrowse link 9 17,817,791 17,823,163 RGD:6480464
G Hspa5 heat shock protein family A (Hsp70) member 5 JBrowse link 3 13,838,304 13,842,763 RGD:6480464
G Hspa8 heat shock protein family A (Hsp70) member 8 JBrowse link 8 44,989,401 44,993,261 RGD:6480464
G Hspa9 heat shock protein family A (Hsp70) member 9 JBrowse link 18 27,731,072 27,749,235 RGD:6480464
G Hspb6 heat shock protein family B (small) member 6 JBrowse link 1 89,008,117 89,010,256 RGD:6480464
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 JBrowse link 1 141,874,354 141,893,674 RGD:6480464
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Ins2 insulin 2 JBrowse link 1 215,856,967 215,858,034 RGD:6480464
G Itga2 integrin subunit alpha 2 JBrowse link 2 46,996,904 47,097,011 RGD:6480464
G Itgav integrin subunit alpha V JBrowse link 3 71,113,269 71,205,958 RGD:6480464
G Itgb1 integrin subunit beta 1 JBrowse link 19 61,677,512 61,725,537 RGD:6480464
G Lipe lipase E, hormone sensitive type JBrowse link 1 82,248,031 82,266,727 RGD:6480464
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6480464
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6480464
G Myl2 myosin light chain 2 JBrowse link 12 39,951,863 39,959,065 RGD:6480464
G Nefh neurofilament heavy JBrowse link 14 85,181,572 85,191,557 RGD:6480464
G Nfkb1 nuclear factor kappa B subunit 1 JBrowse link 2 240,773,520 240,890,053 RGD:6480464
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:6480464
G Ntf3 neurotrophin 3 JBrowse link 4 158,636,883 158,705,886 RGD:6480464
G P2rx7 purinergic receptor P2X 7 JBrowse link 12 39,353,613 39,396,042 RGD:6480464
G P2ry12 purinergic receptor P2Y12 JBrowse link 2 149,440,807 149,482,592 RGD:6480464
G Phb prohibitin JBrowse link 10 83,476,107 83,488,878 RGD:6480464
G Phgdh phosphoglycerate dehydrogenase JBrowse link 2 200,484,245 200,513,564 RGD:6480464
G Pkm pyruvate kinase M1/2 JBrowse link 8 64,480,963 64,502,957 RGD:6480464
G Ppargc1a PPARG coactivator 1 alpha JBrowse link 14 63,095,291 63,190,688 RGD:6480464
G Ppp2r1a protein phosphatase 2 scaffold subunit A alpha JBrowse link 1 60,717,386 60,736,629 RGD:6480464
G Prdx6 peroxiredoxin 6 JBrowse link 13 79,077,567 79,088,113 RGD:6480464
G Prkce protein kinase C, epsilon JBrowse link 6 9,483,400 9,973,396 RGD:6480464
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6480464
G Ren renin JBrowse link 13 50,502,724 50,513,953 RGD:6480464
G Sct secretin JBrowse link 1 214,264,865 214,277,437 RGD:6480464
G Serpine1 serpin family E member 1 JBrowse link 12 22,641,104 22,651,482 RGD:6480464
G Slc22a3 solute carrier family 22 member 3 JBrowse link 1 48,433,079 48,521,261 RGD:6480464
G Slc29a4 solute carrier family 29 member 4 JBrowse link 12 13,914,114 13,924,511 RGD:6480464
G Sod1 superoxide dismutase 1 JBrowse link 11 30,363,282 30,368,858 RGD:6480464
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:6480464
G Suclg2 succinate-CoA ligase GDP-forming subunit beta JBrowse link 4 127,552,100 127,824,970 RGD:6480464
G Th tyrosine hydroxylase JBrowse link 1 216,073,034 216,080,287 RGD:6480464
G Thy1 Thy-1 cell surface antigen JBrowse link 8 48,382,121 48,387,271 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Vdac1 voltage-dependent anion channel 1 JBrowse link 10 37,724,915 37,752,827 RGD:6480464
G Xdh xanthine dehydrogenase JBrowse link 6 25,149,570 25,211,273 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19716
    role 19663
      biological role 19661
        molecular messenger 18042
          monoamine molecular messenger 564
            catecholamine 519
              adrenaline 96
                (R)-adrenaline + 96
                (S)-adrenaline 0
                dipivefrin 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19716
    subatomic particle 19712
      composite particle 19712
        hadron 19712
          baryon 19712
            nucleon 19712
              atomic nucleus 19712
                atom 19712
                  main group element atom 19598
                    main group molecular entity 19598
                      s-block molecular entity 19361
                        hydrogen molecular entity 19350
                          hydrides 18280
                            inorganic hydride 17204
                              pnictogen hydride 17166
                                nitrogen hydride 17003
                                  azane 16693
                                    ammonia 16690
                                      organic amino compound 16689
                                        aralkylamino compound 879
                                          monoamine 564
                                            monoamine molecular messenger 564
                                              catecholamine 519
                                                adrenaline 96
                                                  (R)-adrenaline + 96
                                                  (S)-adrenaline 0
                                                  dipivefrin 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.