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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:carbohydrate acid
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Accession:CHEBI:33720 term browser browse the term
Synonyms:related_synonym: carbohydrate acids
 cyclic_relationship: is_conjugate_acid_of CHEBI:33721


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17beta-estradiol 17-glucosiduronic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca8 ATP binding cassette subfamily A member 8 increases uptake
multiple interactions
ISO ABCA8 protein results in increased uptake of estradiol-17 beta-glucuronide
Adenosine Triphosphate affects the reaction [ABCA8 protein results in increased uptake of estradiol-17 beta-glucuronide]; Digoxin inhibits the reaction [ABCA8 protein results in increased uptake of estradiol-17 beta-glucuronide]; dofequidar inhibits the reaction [ABCA8 protein results in increased uptake of estradiol-17 beta-glucuronide]; ochratoxin A inhibits the reaction [ABCA8 protein results in increased uptake of estradiol-17 beta-glucuronide]; Probenecid inhibits the reaction [ABCA8 protein results in increased uptake of estradiol-17 beta-glucuronide]; Verapamil inhibits the reaction [ABCA8 protein results in increased uptake of estradiol-17 beta-glucuronide]; verlukast inhibits the reaction [ABCA8 protein results in increased uptake of estradiol-17 beta-glucuronide]
CTD PMID:12379217 NCBI chr10:98,236,919...98,308,288
Ensembl chr10:98,237,141...98,294,522
JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity
decreases secretion
affects localization
multiple interactions
EXP estradiol-17 beta-glucuronide results in decreased activity of ABCB11 protein
estradiol-17 beta-glucuronide results in decreased secretion of ABCB11 protein
estradiol-17 beta-glucuronide affects the localization of ABCB11 protein
estradiol-17 beta-glucuronide affects the localization of and affects the activity of ABCB11 protein; Go 6976 inhibits the reaction [estradiol-17 beta-glucuronide affects the localization of ABCB11 protein]; IGF1R protein affects the reaction [estradiol-17 beta-glucuronide affects the localization of ABCB11 protein]; tyrphostin AG 1024 inhibits the reaction [estradiol-17 beta-glucuronide affects the localization of ABCB11 protein]; wortmannin inhibits the reaction [estradiol-17 beta-glucuronide affects the localization of ABCB11 protein]
CTD PMID:10869290, PMID:12702498, PMID:12893835, PMID:15763547, PMID:18972403, PMID:20815017, PMID:29090346 NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A affects response to substance
multiple interactions
increases transport
ISO
EXP
ABCB1 affects the susceptibility to estradiol-17 beta-glucuronide
Daunorubicin inhibits the reaction [ABCB1 results in increased transport of estradiol-17 beta-glucuronide]; estriol 17-glucuronide inhibits the reaction [ABCB1 results in increased transport of estradiol-17 beta-glucuronide]; estriol-16 alpha-(beta-D-glucuronide) inhibits the reaction [ABCB1 results in increased transport of estradiol-17 beta-glucuronide]
CTD PMID:9794924 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 affects export ISO ABCB4 protein affects the export of estradiol-17 beta-glucuronide CTD PMID:11302927 NCBI chr 4:22,133,984...22,192,687
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 affects transport
increases export
multiple interactions
increases uptake
increases transport
ISO ABCC1 protein affects the transport of estradiol-17 beta-glucuronide
ABCC1 protein results in increased export of estradiol-17 beta-glucuronide
[Glutathione co-treated with Apigenin] affects the reaction [ABCC1 protein results in increased uptake of estradiol-17 beta-glucuronide]; [Glutathione co-treated with naringenin] inhibits the reaction [ABCC1 protein results in increased uptake of estradiol-17 beta-glucuronide]; Adenosine Triphosphate promotes the reaction [ABCC1 protein affects the transport of estradiol-17 beta-glucuronide]; BAY u9773 inhibits the reaction [ABCC1 protein mutant form results in increased transport of estradiol-17 beta-glucuronide]; BAY u9773 inhibits the reaction [ABCC1 protein results in increased transport of estradiol-17 beta-glucuronide]; estradiol-17 beta-glucuronide inhibits the reaction [ABCC1 protein affects the transport of Leukotriene C4]; estradiol-17 beta-glucuronide inhibits the reaction [Adenosine Diphosphate binds to ABCC1 protein mutant form]; estradiol-17 beta-glucuronide inhibits the reaction [Adenosine Diphosphate binds to ABCC1 protein]; estradiol-17 beta-glucuronide inhibits the reaction [Glutathione promotes the reaction [ABCC1 results in increased transport of methylarsine analog]]; kaempferol affects the reaction [ABCC1 protein results in increased uptake of estradiol-17 beta-glucuronide]; Quercetin affects the reaction [ABCC1 protein results in increased uptake of estradiol-17 beta-glucuronide]; S-decylglutathione inhibits the reaction [ABCC1 protein mutant form results in increased transport of estradiol-17 beta-glucuronide]; S-decylglutathione inhibits the reaction [ABCC1 protein results in increased transport of estradiol-17 beta-glucuronide]; verlukast inhibits the reaction [ABCC1 protein mutant form results in increased transport of estradiol-17 beta-glucuronide]; verlukast inhibits the reaction [ABCC1 protein results in increased transport of estradiol-17 beta-glucuronide]
ABCC1 protein mutant form results in increased transport of estradiol-17 beta-glucuronide; ABCC1 protein results in increased transport of estradiol-17 beta-glucuronide
CTD PMID:11278867, PMID:11306701, PMID:15459206, PMID:18336795, PMID:21918036, PMID:27297967 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 affects export
decreases secretion
affects localization
affects transport
multiple interactions
increases transport
affects response to substance
ISO
EXP
ABCC2 protein affects the export of estradiol-17 beta-glucuronide
estradiol-17 beta-glucuronide results in decreased secretion of ABCC2 protein
estradiol-17 beta-glucuronide affects the localization of ABCC2 protein
ABCC2 protein affects the transport of estradiol-17 beta-glucuronide
abietic acid inhibits the reaction [ABCC2 protein results in increased transport of estradiol-17 beta-glucuronide]; AG 1879 inhibits the reaction [estradiol-17 beta-glucuronide results in decreased activity of ABCC2 protein]; Bucladesine inhibits the reaction [estradiol-17 beta-glucuronide affects the localization of ABCC2 protein]; CL 387785 inhibits the reaction [estradiol-17 beta-glucuronide affects the localization of and results in decreased activity of ABCC2 protein]; EGF protein inhibits the reaction [Fulvestrant inhibits the reaction [estradiol-17 beta-glucuronide results in decreased activity of ABCC2 protein]]; EGFR protein promotes the reaction [estradiol-17 beta-glucuronide affects the localization of and results in decreased activity of ABCC2 protein]; estradiol-17 beta-glucuronide affects the localization of and results in decreased activity of ABCC2 protein; Fulvestrant inhibits the reaction [estradiol-17 beta-glucuronide results in decreased activity of ABCC2 protein]; Glycyrrhetinic Acid inhibits the reaction [ABCC2 protein results in increased transport of estradiol-17 beta-glucuronide]; Go 6976 inhibits the reaction [estradiol-17 beta-glucuronide affects the localization of ABCC2 protein]; IGF1R protein affects the reaction [estradiol-17 beta-glucuronide affects the localization of ABCC2 protein]; Protein Kinase Inhibitors inhibits the reaction [estradiol-17 beta-glucuronide results in decreased activity of ABCC2 protein]; RTKI cpd inhibits the reaction [estradiol-17 beta-glucuronide affects the localization of and results in decreased activity of ABCC2 protein]; tyrphostin AG 1024 inhibits the reaction [estradiol-17 beta-glucuronide affects the localization of ABCC2 protein]; Wortmannin inhibits the reaction [estradiol-17 beta-glucuronide affects the localization of ABCC2 protein]
ABCC2 protein modified form results in increased transport of estradiol-17 beta-glucuronide; ABCC2 protein results in increased transport of estradiol-17 beta-glucuronide
ABCC2 protein affects the susceptibility to estradiol-17 beta-glucuronide
[Adenosine Triphosphate co-treated with ABCC2 protein] results in increased uptake of estradiol-17 beta-glucuronide; [SLCO1B1 protein co-treated with ABCC2 protein] results in increased transport of estradiol-17 beta-glucuronide; [SLCO1B1 protein co-treated with ABCC2 protein] results in increased uptake of estradiol-17 beta-glucuronide; [SLCO1B3 protein co-treated with ABCC2 protein] results in increased uptake of estradiol-17 beta-glucuronide; Bile Acids and Salts promotes the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide]; estradiol-17 beta-glucuronide promotes the reaction [ABCC2 protein affects the transport of Bile Acids and Salts]; estradiol-17 beta-glucuronide results in decreased activity of and affects the localization of ABCC2 protein; Ethinyl Estradiol metabolite promotes the reaction [ABCC2 protein results in increased uptake of estradiol-17 beta-glucuronide]; Furosemide promotes the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide]; Go 6976 inhibits the reaction [estradiol-17 beta-glucuronide affects the localization of ABCC2 protein]; Indomethacin promotes the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide]; Pantoprazole promotes the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide]; Penicillin G promotes the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide]; Probenecid promotes the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide]; sulfanitran promotes the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide]; verlukast inhibits the reaction [[Adenosine Triphosphate co-treated with ABCC2 protein] results in increased uptake of estradiol-17 beta-glucuronide]
CTD PMID:11500505, PMID:12029626, PMID:12642476, PMID:12702498, PMID:12702717, PMID:12704183, PMID:12893835, PMID:14722317, PMID:15652233, PMID:15846474, PMID:15901800, PMID:15904671, PMID:17463180, PMID:18180276, PMID:18436619, PMID:18972403, PMID:19628752, PMID:20815017, PMID:25813982, PMID:29052767, PMID:29090346, PMID:32003934 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 affects transport
multiple interactions
increases transport
increases activity
ISO ABCC3 protein affects the transport of estradiol-17 beta-glucuronide
Bile Acids and Salts inhibits the reaction [ABCC3 protein affects the transport of estradiol-17 beta-glucuronide]; Ethinyl Estradiol metabolite promotes the reaction [ABCC3 protein results in increased uptake of estradiol-17 beta-glucuronide]; Furosemide inhibits the reaction [ABCC3 protein affects the transport of estradiol-17 beta-glucuronide]; Indomethacin inhibits the reaction [ABCC3 protein affects the transport of estradiol-17 beta-glucuronide]; Probenecid inhibits the reaction [ABCC3 protein affects the transport of estradiol-17 beta-glucuronide]; resveratrol metabolite promotes the reaction [ABCC3 protein results in increased transport of estradiol-17 beta-glucuronide]; resveratrol-4'-O-glucuronide inhibits the reaction [ABCC3 protein results in increased transport of estradiol-17 beta-glucuronide]
estradiol-17 beta-glucuronide results in increased activity of ABCC3 protein
CTD PMID:12704183, PMID:14722317, PMID:17569508, PMID:19114588 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 increases transport
affects export
increases export
ISO ABCC4 protein results in increased transport of estradiol-17 beta-glucuronide
ABCC4 gene SNP affects the export of estradiol-17 beta-glucuronide
ABCC4 protein results in increased export of estradiol-17 beta-glucuronide
CTD PMID:11856762, PMID:27659809 NCBI chr15:103,695,415...103,927,980
Ensembl chr15:103,696,557...103,927,592
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 increases transport
multiple interactions
ISO ABCG2 protein results in increased transport of estradiol-17 beta-glucuronide
Glycyrrhetinic Acid inhibits the reaction [ABCG2 protein results in increased transport of estradiol-17 beta-glucuronide]; lapatinib inhibits the reaction [ABCG2 protein results in increased transport of estradiol-17 beta-glucuronide]
CTD PMID:18436619, PMID:18829547 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation
multiple interactions
EXP estradiol-17 beta-glucuronide results in increased phosphorylation of AKT1 protein
tyrphostin AG 1024 inhibits the reaction [estradiol-17 beta-glucuronide results in increased phosphorylation of AKT1 protein]
CTD PMID:29090346 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Aqp8 aquaporin 8 decreases expression EXP estradiol-17 beta-glucuronide results in decreased expression of AQP8 protein CTD PMID:17110522 NCBI chr 1:193,424,818...193,430,665
Ensembl chr 1:193,424,812...193,430,676
JBrowse link
G Egf epidermal growth factor multiple interactions EXP EGF protein inhibits the reaction [fulvestrant inhibits the reaction [estradiol-17 beta-glucuronide results in decreased activity of ABCC2 protein]] CTD PMID:25813982 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Egfr epidermal growth factor receptor multiple interactions EXP EGFR protein promotes the reaction [estradiol-17 beta-glucuronide affects the localization of and results in decreased activity of ABCC2 protein]; estradiol-17 beta-glucuronide results in increased phosphorylation of and results in increased activity of EGFR protein; RTKI cpd inhibits the reaction [estradiol-17 beta-glucuronide results in increased phosphorylation of and results in increased activity of EGFR protein] CTD PMID:25813982 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions EXP estradiol-17 beta-glucuronide results in increased phosphorylation of and results in increased activity of ESR1 protein CTD PMID:25813982 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Hgf hepatocyte growth factor multiple interactions
increases uptake
EXP [HGF protein results in increased expression of SLCO1A1 protein] which results in increased uptake of estradiol-17 beta-glucuronide; ochratoxin A inhibits the reaction [HGF protein results in increased uptake of estradiol-17 beta-glucuronide]; Ouabain inhibits the reaction [HGF protein results in increased uptake of estradiol-17 beta-glucuronide]; SLCO1A1 protein affects the reaction [HGF protein results in increased uptake of estradiol-17 beta-glucuronide]; Sulfobromophthalein inhibits the reaction [HGF protein results in increased uptake of estradiol-17 beta-glucuronide] CTD PMID:18031729 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
JBrowse link
G Igf1r insulin-like growth factor 1 receptor multiple interactions
increases phosphorylation
EXP 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [estradiol-17 beta-glucuronide results in increased phosphorylation of IGF1R protein]; IGF1R protein affects the reaction [estradiol-17 beta-glucuronide affects the localization of ABCB11 protein]; IGF1R protein affects the reaction [estradiol-17 beta-glucuronide affects the localization of ABCC2 protein] CTD PMID:29090346 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Ocln occludin affects localization EXP estradiol-17 beta-glucuronide affects the localization of OCLN protein CTD PMID:17463180 NCBI chr 2:30,527,327...30,577,218
Ensembl chr 2:30,527,715...30,577,218
JBrowse link
G Prkca protein kinase C, alpha multiple interactions
affects localization
EXP Go 6976 inhibits the reaction [estradiol-17 beta-glucuronide affects the localization of PRKCA protein] CTD PMID:18972403 NCBI chr10:96,186,509...96,585,168
Ensembl chr10:96,191,133...96,584,947
JBrowse link
G Slc22a8 solute carrier family 22 member 8 multiple interactions
affects transport
EXP
ISO
estradiol-17 beta-glucuronide inhibits the reaction [SLC22A8 protein results in increased uptake of Cimetidine]
SLC22A8 protein affects the transport of estradiol-17 beta-glucuronide
CTD PMID:11306713, PMID:15319347 NCBI chr 1:224,799,444...224,818,482
Ensembl chr 1:224,800,252...224,818,482
JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 affects uptake
increases uptake
multiple interactions
ISO
EXP
SLCO1A4 protein affects the uptake of estradiol-17 beta-glucuronide
SLCO1A2 protein results in increased uptake of estradiol-17 beta-glucuronide
Bile Acids and Salts inhibits the reaction [SLCO1A2 protein results in increased uptake of estradiol-17 beta-glucuronide]
CTD PMID:19464309, PMID:21561886 NCBI chr 4:175,969,549...176,026,227
Ensembl chr 4:175,969,549...176,026,163
JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 increases uptake
increases import
multiple interactions
affects response to substance
EXP
ISO
SLCO1B3 protein results in increased uptake of estradiol-17 beta-glucuronide
SLCO1B3 results in increased import of estradiol-17 beta-glucuronide
2,2',4,4',5,6'-hexabromodiphenyl ether inhibits the reaction [SLCO1B3 results in increased import of estradiol-17 beta-glucuronide]; 2,2',4,4'-tetrabromodiphenyl ether inhibits the reaction [SLCO1B3 results in increased import of estradiol-17 beta-glucuronide]; [SLCO1B3 protein co-treated with ABCC2 protein] results in increased uptake of estradiol-17 beta-glucuronide; pentabromodiphenyl ether inhibits the reaction [SLCO1B3 results in increased import of estradiol-17 beta-glucuronide]; Rifampin inhibits the reaction [SLCO1B3 protein results in increased uptake of estradiol-17 beta-glucuronide]
SLCO1B2 protein affects the susceptibility to estradiol-17 beta-glucuronide
Bile Acids and Salts inhibits the reaction [SLCO1B3 protein results in increased uptake of estradiol-17 beta-glucuronide]
CTD PMID:18180276, PMID:18296417, PMID:19464309, PMID:20176623, PMID:32003934, PMID:32305507 NCBI chr 4:175,814,118...175,881,775
Ensembl chr 4:175,814,118...175,881,768
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions EXP estradiol-17 beta-glucuronide results in increased phosphorylation of and results in increased activity of SRC protein; Protein Kinase Inhibitors inhibits the reaction [estradiol-17 beta-glucuronide results in increased phosphorylation of and results in increased activity of SRC protein]; RTKI cpd inhibits the reaction [estradiol-17 beta-glucuronide results in increased phosphorylation of and results in increased activity of SRC protein] CTD PMID:25813982 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642
JBrowse link
G Tjp1 tight junction protein 1 affects localization EXP estradiol-17 beta-glucuronide affects the localization of TJP1 protein CTD PMID:17463180 NCBI chr 1:126,146,489...126,515,359
Ensembl chr 1:126,146,489...126,227,469
JBrowse link
17beta-estradiol 3-glucosiduronic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity EXP estradiol-3-glucuronide results in decreased activity of ABCB11 protein CTD PMID:10869290 NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
JBrowse link
G Kl Klotho multiple interactions
increases hydrolysis
ISO estradiol-3-glucuronide inhibits the reaction [KL protein results in increased hydrolysis of Glucuronides]
KL protein results in increased hydrolysis of estradiol-3-glucuronide
CTD PMID:14701853 NCBI chr12:942,974...987,206
Ensembl chr12:943,006...987,551
JBrowse link
2,3-bisphospho-D-glyceric acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arf6 ADP-ribosylation factor 6 multiple interactions ISO 2,3-Diphosphoglycerate inhibits the reaction [ARF6 protein affects the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased abundance of Superoxides]]; 2,3-Diphosphoglycerate inhibits the reaction [ARF6 protein mutant form promotes the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased abundance of Superoxides]] CTD PMID:10931844 NCBI chr 6:91,697,109...91,698,257
Ensembl chr 6:91,697,109...91,698,255
JBrowse link
G Bglap bone gamma-carboxyglutamate protein decreases activity ISO 2,3-Diphosphoglycerate results in decreased activity of BGLAP protein CTD PMID:16857255 NCBI chr 2:187,741,770...187,748,445
Ensembl chr 2:187,741,770...187,742,747
JBrowse link
G Pld1 phospholipase D1 decreases activity ISO 2,3-Diphosphoglycerate results in decreased activity of PLD1 protein CTD PMID:16857255 NCBI chr 2:113,651,967...113,849,403
Ensembl chr 2:113,652,348...113,849,403
JBrowse link
G Sts steroid sulfatase multiple interactions ISO 2,3-Diphosphoglycerate inhibits the reaction [Tretinoin results in increased activity of STS protein] CTD PMID:16178010 NCBI chr  X:45,420,418...45,428,748
Ensembl chr  X:45,420,596...45,428,750
JBrowse link
2,3-bisphosphoglyceric acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arf6 ADP-ribosylation factor 6 multiple interactions ISO 2,3-Diphosphoglycerate inhibits the reaction [ARF6 protein affects the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased abundance of Superoxides]]; 2,3-Diphosphoglycerate inhibits the reaction [ARF6 protein mutant form promotes the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased abundance of Superoxides]] CTD PMID:10931844 NCBI chr 6:91,697,109...91,698,257
Ensembl chr 6:91,697,109...91,698,255
JBrowse link
G Bglap bone gamma-carboxyglutamate protein decreases activity ISO 2,3-Diphosphoglycerate results in decreased activity of BGLAP protein CTD PMID:16857255 NCBI chr 2:187,741,770...187,748,445
Ensembl chr 2:187,741,770...187,742,747
JBrowse link
G Pld1 phospholipase D1 decreases activity ISO 2,3-Diphosphoglycerate results in decreased activity of PLD1 protein CTD PMID:16857255 NCBI chr 2:113,651,967...113,849,403
Ensembl chr 2:113,652,348...113,849,403
JBrowse link
G Sts steroid sulfatase multiple interactions ISO 2,3-Diphosphoglycerate inhibits the reaction [Tretinoin results in increased activity of STS protein] CTD PMID:16178010 NCBI chr  X:45,420,418...45,428,748
Ensembl chr  X:45,420,596...45,428,750
JBrowse link
3-phosphoglyceric acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gapdh glyceraldehyde-3-phosphate dehydrogenase multiple interactions EXP [GAPDH protein co-treated with 3-phosphoglycerate co-treated with NAD] results in increased chemical synthesis of sodium arsenite; [GAPDH protein co-treated with 3-phosphoglycerate co-treated with NAD] results in increased reduction of sodium arsenate analog; heptelidic acid inhibits the reaction [[GAPDH protein co-treated with 3-phosphoglycerate co-treated with NAD] results in increased reduction of sodium arsenate analog] CTD PMID:15788719 NCBI chr 4:157,676,336...157,680,322
Ensembl chr 4:157,676,595...157,679,962
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 multiple interactions
increases abundance
ISO Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of 3-phosphoglycerate] CTD PMID:27469509 NCBI chr 1:141,874,354...141,893,674
Ensembl chr 1:141,866,283...141,893,705
JBrowse link
4-methylumbelliferone beta-D-glucuronide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 multiple interactions ISO [UGT1A1 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide; pterostilbene inhibits the reaction [[UGT1A1 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide] CTD PMID:31812603 NCBI chr 9:95,295,701...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 multiple interactions ISO [UGT1A3 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide; pterostilbene inhibits the reaction [[UGT1A3 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide] CTD PMID:31812603 NCBI chr 9:95,285,592...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 multiple interactions ISO [UGT1A6 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide; pterostilbene inhibits the reaction [[UGT1A6 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide] CTD PMID:31812603 NCBI chr 9:95,241,609...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a8 UDP glucuronosyltransferase family 1 member A8 multiple interactions ISO [UGT1A8 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide; pterostilbene inhibits the reaction [[UGT1A8 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide] CTD PMID:31812603 NCBI chr 9:95,221,474...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 multiple interactions ISO [UGT1A9 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide; pterostilbene inhibits the reaction [[UGT1A9 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide] CTD PMID:31812603 NCBI chr 9:95,161,157...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 multiple interactions ISO [UGT2B7 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide; pterostilbene inhibits the reaction [[UGT2B7 protein results in increased metabolism of Hymecromone] which results in increased chemical synthesis of 4-methylumbelliferyl glucuronide] CTD PMID:31812603 NCBI chr14:22,597,103...22,619,968 JBrowse link
4-nitrophenyl beta-D-glucuronide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc4 ATP binding cassette subfamily C member 4 multiple interactions ISO 4-nitrophenylglucuronide inhibits the reaction [ABCC4 protein results in increased transport of Methotrexate] CTD PMID:11856762 NCBI chr15:103,695,415...103,927,980
Ensembl chr15:103,696,557...103,927,592
JBrowse link
7-hydroxycoumarin O(7)-glucosiduronic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ugt2b15 UDP glucuronosyltransferase family 2 member B15 increases abundance EXP UGT2B15 protein results in increased abundance of 7-hydroxycoumarin glucuronide CTD PMID:7574722 NCBI chr14:22,375,428...22,486,291
Ensembl chr14:22,375,955...22,534,720
JBrowse link
acetaminophen O-beta-D-glucosiduronic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc3 ATP binding cassette subfamily C member 3 increases activity
affects export
multiple interactions
ISO
EXP
acetaminophen glucuronide results in increased activity of ABCC3 protein
ABCC3 protein affects the export of acetaminophen glucuronide
Ethinyl Estradiol promotes the reaction [ABCC3 protein results in increased secretion of acetaminophen glucuronide]
CTD PMID:16250050, PMID:16554369, PMID:17569508 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Ins2 insulin 2 increases abundance ISO INS protein results in increased abundance of acetaminophen glucuronide CTD PMID:26739624 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase multiple interactions ISO OGT gene mutant form inhibits the reaction [Acetaminophen results in increased abundance of acetaminophen glucuronide] CTD PMID:29325178 NCBI chr  X:71,540,870...71,585,906
Ensembl chr  X:71,528,988...71,585,908
JBrowse link
Aldosterone 18-glucuronide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 multiple interactions
increases chemical synthesis
ISO alclofenac inhibits the reaction [UGT2B7 protein results in increased chemical synthesis of aldosterone 18-glucuronide]; Anti-Inflammatory Agents, Non-Steroidal inhibits the reaction [UGT2B7 protein results in increased chemical synthesis of aldosterone 18-glucuronide]; cicloprofen inhibits the reaction [UGT2B7 protein results in increased chemical synthesis of aldosterone 18-glucuronide]; Diclofenac inhibits the reaction [UGT2B7 protein results in increased chemical synthesis of aldosterone 18-glucuronide]; Diflunisal inhibits the reaction [UGT2B7 protein results in increased chemical synthesis of aldosterone 18-glucuronide]; Fenoprofen inhibits the reaction [UGT2B7 protein results in increased chemical synthesis of aldosterone 18-glucuronide]; Ibuprofen inhibits the reaction [UGT2B7 protein results in increased chemical synthesis of aldosterone 18-glucuronide]; Indomethacin inhibits the reaction [UGT2B7 protein results in increased chemical synthesis of aldosterone 18-glucuronide]; Ketoprofen inhibits the reaction [UGT2B7 protein results in increased chemical synthesis of aldosterone 18-glucuronide]; Ketorolac inhibits the reaction [UGT2B7 protein results in increased chemical synthesis of aldosterone 18-glucuronide]; Meclofenamic Acid inhibits the reaction [UGT2B7 protein results in increased chemical synthesis of aldosterone 18-glucuronide]; Mefenamic Acid inhibits the reaction [UGT2B7 protein results in increased chemical synthesis of aldosterone 18-glucuronide]; Naproxen inhibits the reaction [UGT2B7 protein results in increased chemical synthesis of aldosterone 18-glucuronide]; pirprofen inhibits the reaction [UGT2B7 protein results in increased chemical synthesis of aldosterone 18-glucuronide]; tiaprofenic acid inhibits the reaction [UGT2B7 protein results in increased chemical synthesis of aldosterone 18-glucuronide] CTD PMID:19740398 NCBI chr14:22,597,103...22,619,968 JBrowse link
alpha-Naphthyl-beta-D-glucuronide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc4 ATP binding cassette subfamily C member 4 multiple interactions ISO naphthyl glucuronide inhibits the reaction [ABCC4 protein results in increased transport of Methotrexate] CTD PMID:11856762 NCBI chr15:103,695,415...103,927,980
Ensembl chr15:103,696,557...103,927,592
JBrowse link
androsterone 3-glucosiduronic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kl Klotho multiple interactions ISO androsterone glucuronide inhibits the reaction [KL protein results in increased hydrolysis of Glucuronides] CTD PMID:14701853 NCBI chr12:942,974...987,206
Ensembl chr12:943,006...987,551
JBrowse link
baicalin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions
increases expression
EXP baicalin results in increased expression of and results in increased activity of ACHE protein
baicalin results in increased expression of ACHE mRNA
CTD PMID:27019979 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Ahr aryl hydrocarbon receptor increases activity ISO baicalin results in increased activity of AHR protein CTD PMID:17869316, PMID:26204831 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Alox5 arachidonate 5-lipoxygenase multiple interactions EXP baicalin inhibits the reaction [Hydrogen Peroxide affects the localization of and results in increased activity of ALOX5 protein] CTD PMID:20139896 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303
JBrowse link
G Atf2 activating transcription factor 2 multiple interactions EXP baicalin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of ATF2 protein] CTD PMID:24312512 NCBI chr 3:60,721,137...60,795,951
Ensembl chr 3:60,721,135...60,795,951
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
ISO
EXP
baicalin results in increased expression of BAX protein
baicalin inhibits the reaction [Rotenone affects the expression of BAX protein]
CTD PMID:21457722, PMID:25423838 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP baicalin inhibits the reaction [Rotenone affects the expression of BCL2 protein] CTD PMID:25423838 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Casp3 caspase 3 multiple interactions EXP baicalin inhibits the reaction [Rotenone affects the expression of CASP3 protein] CTD PMID:25423838 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO baicalin results in decreased expression of CCNA2 protein CTD PMID:21457722 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214
JBrowse link
G Ccnd1 cyclin D1 increases expression
decreases expression
multiple interactions
ISO baicalin results in increased expression of CCND1 mRNA
baicalin results in decreased expression of CCND1 protein
N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [baicalin results in increased expression of CCND1 mRNA]
CTD PMID:19160421, PMID:21457722 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Col1a2 collagen type I alpha 2 chain multiple interactions EXP baicalin inhibits the reaction [TGFB1 protein results in increased expression of COL1A2 mRNA] CTD PMID:19474275 NCBI chr 4:31,534,225...31,569,152
Ensembl chr 4:31,534,225...31,569,151
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
ISO 3',4'-dimethoxyflavone inhibits the reaction [baicalin results in increased expression of CYP1A1 mRNA]; 3',4'-dimethoxyflavone inhibits the reaction [baicalin results in increased expression of CYP1A1 protein]; baicalin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]
baicalin results in increased expression of CYP1A1 mRNA; baicalin results in increased expression of CYP1A1 protein
CTD PMID:18451504, PMID:26204831 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
increases expression
ISO 3',4'-dimethoxyflavone inhibits the reaction [baicalin results in increased expression of CYP1A2 mRNA]; 3',4'-dimethoxyflavone inhibits the reaction [baicalin results in increased expression of CYP1A2 protein]
resveratrol inhibits the reaction [baicalin results in increased expression of CYP1A2 mRNA]; resveratrol inhibits the reaction [baicalin results in increased expression of CYP1A2 protein]
baicalin results in increased expression of CYP1A2 mRNA; baicalin results in increased expression of CYP1A2 protein
CTD PMID:26204831 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Egf epidermal growth factor multiple interactions ISO baicalin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; baicalin inhibits the reaction [EGF protein results in increased phosphorylation of ELK1 protein] CTD PMID:25625231 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO baicalin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:25625231 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Elk1 ETS transcription factor ELK1 multiple interactions ISO baicalin inhibits the reaction [EGF protein results in increased phosphorylation of ELK1 protein] CTD PMID:25625231 NCBI chr  X:1,287,875...1,304,822
Ensembl chr  X:1,297,099...1,304,822
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions ISO baicalin inhibits the reaction [Palmitic Acid results in increased phosphorylation of ERN1 protein] CTD PMID:29031535 NCBI chr10:94,588,555...94,682,072
Ensembl chr10:94,588,555...94,681,914
JBrowse link
G Foxa2 forkhead box A2 decreases expression ISO baicalin results in decreased expression of FOXA2 mRNA; baicalin results in decreased expression of FOXA2 protein CTD PMID:32687838 NCBI chr 3:142,383,084...142,387,493
Ensembl chr 3:142,383,278...142,387,481
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 multiple interactions EXP baicalin inhibits the reaction [tert-Butylhydroperoxide results in increased activity of GOT1 protein] CTD PMID:15645217 NCBI chr 1:263,246,248...263,269,762
Ensembl chr 1:263,246,248...263,269,762
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP baicalin inhibits the reaction [tert-Butylhydroperoxide results in increased activity of GPT protein] CTD PMID:15645217 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Hes1 hes family bHLH transcription factor 1 increases expression
multiple interactions
ISO baicalin results in increased expression of HES1 mRNA
N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [baicalin results in increased expression of HES1 mRNA]
CTD PMID:19160421 NCBI chr11:74,312,837...74,315,249
Ensembl chr11:74,312,806...74,315,248
JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 increases expression
multiple interactions
ISO baicalin results in increased expression of HEY1 mRNA
N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [baicalin results in increased expression of HEY1 mRNA]
CTD PMID:19160421 NCBI chr 2:95,320,147...95,322,701
Ensembl chr 2:95,320,283...95,322,696
JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 multiple interactions
increases expression
ISO N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [baicalin results in increased expression of HEY2 mRNA] CTD PMID:19160421 NCBI chr 1:29,191,170...29,201,257
Ensembl chr 1:29,191,192...29,201,531
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO
EXP
baicalin promotes the reaction [Carbon Tetrachloride results in increased expression of HMOX1 mRNA]; baicalin promotes the reaction [Carbon Tetrachloride results in increased expression of HMOX1 protein]
baicalin results in increased expression of HMOX1 mRNA; baicalin results in increased expression of HMOX1 protein
CTD PMID:16824337, PMID:18187930 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hnf1a HNF1 homeobox A multiple interactions
decreases expression
ISO baicalin inhibits the reaction [HNF4A protein binds to HNF1A promoter]; HNF1A protein promotes the reaction [baicalin results in decreased secretion of Hepatitis B Surface Antigens]; HNF4A protein promotes the reaction [baicalin results in decreased expression of HNF1A mRNA]; HNF4A protein promotes the reaction [baicalin results in decreased expression of HNF1A protein]
baicalin results in decreased expression of HNF1A mRNA; baicalin results in decreased expression of HNF1A protein
CTD PMID:32687838 NCBI chr12:47,407,811...47,433,342
Ensembl chr12:47,407,811...47,433,342
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha decreases expression
multiple interactions
ISO baicalin results in decreased expression of HNF4A protein
baicalin inhibits the reaction [HNF4A protein binds to HNF1A promoter]; HNF4A protein promotes the reaction [baicalin results in decreased expression of HNF1A mRNA]; HNF4A protein promotes the reaction [baicalin results in decreased expression of HNF1A protein]; HNF4A protein promotes the reaction [baicalin results in decreased secretion of Hepatitis B Surface Antigens]
baicalin results in decreased expression of HNF4A mRNA; baicalin results in decreased expression of HNF4A protein
CTD PMID:32687838 NCBI chr 3:159,902,441...159,965,003
Ensembl chr 3:159,902,441...159,965,003
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO baicalin inhibits the reaction [Palmitic Acid results in increased secretion of IL1B protein] CTD PMID:29031535 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 decreases expression
multiple interactions
EXP
ISO
baicalin results in decreased expression of IL6 mRNA; baicalin results in decreased expression of IL6 protein
baicalin inhibits the reaction [Palmitic Acid results in increased secretion of IL6 protein]
CTD PMID:22019745, PMID:29031535 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor decreases expression EXP baicalin results in decreased expression of MYD88 protein CTD PMID:22019745 NCBI chr 8:128,022,512...128,027,462
Ensembl chr 8:128,022,473...128,026,841
JBrowse link
G Nfkbia NFKB inhibitor alpha increases expression EXP baicalin results in increased expression of NFKBIA protein CTD PMID:22019745 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO baicalin inhibits the reaction [Palmitic Acid results in increased expression of NLRP3 protein] CTD PMID:29031535 NCBI chr10:45,884,324...45,918,290
Ensembl chr10:45,893,018...45,918,254
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
decreases expression
EXP
ISO
baicalin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; baicalin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; mifobate inhibits the reaction [baicalin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]]
baicalin results in decreased expression of NOS2 mRNA; baicalin results in decreased expression of NOS2 protein
baicalin inhibits the reaction [Carbon Tetrachloride results in increased expression of NOS2 mRNA]; baicalin inhibits the reaction [Carbon Tetrachloride results in increased expression of NOS2 protein]
CTD PMID:18187930, PMID:22019745, PMID:24312512 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Notch1 notch receptor 1 increases activity
increases expression
ISO baicalin results in increased activity of NOTCH1 protein
baicalin results in increased expression of NOTCH1 mRNA
CTD PMID:19160421 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Pkm pyruvate kinase M1/2 increases activity ISO baicalin results in increased activity of PKM protein CTD PMID:25388478 NCBI chr 8:64,480,963...64,502,957
Ensembl chr 8:64,481,172...64,502,722
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions EXP baicalin inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased phosphorylation of and results in decreased activity of PPARG protein] CTD PMID:24312512 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Prima1 proline rich membrane anchor 1 increases expression EXP baicalin results in increased expression of PRIMA1 mRNA CTD PMID:27019979 NCBI chr 6:127,075,954...127,127,985
Ensembl chr 6:127,075,954...127,127,413
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression EXP baicalin results in decreased expression of PTGS2 mRNA; baicalin results in decreased expression of PTGS2 protein CTD PMID:22019745 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP baicalin affects the localization of and results in decreased expression of RELA protein CTD PMID:22019745 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP baicalin inhibits the reaction [TGFB1 protein results in increased expression of COL1A2 mRNA] CTD PMID:19474275 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tlr4 toll-like receptor 4 decreases expression
multiple interactions
EXP baicalin results in decreased expression of TLR4 protein
baicalin inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]
CTD PMID:22019745, PMID:24312512 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases expression
ISO
EXP
baicalin inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF mRNA]; baicalin inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF protein]
baicalin results in decreased expression of TNF mRNA; baicalin results in decreased expression of TNF protein
baicalin inhibits the reaction [Paraquat results in increased expression of TNF protein]
CTD PMID:16824337, PMID:18187930, PMID:22019745 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tp53 tumor protein p53 increases expression ISO baicalin results in increased expression of TP53 protein CTD PMID:21457722 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Txnip thioredoxin interacting protein multiple interactions ISO baicalin inhibits the reaction [Palmitic Acid results in increased expression of TXNIP protein]; dorsomorphin inhibits the reaction [baicalin inhibits the reaction [Palmitic Acid results in increased expression of TXNIP protein]] CTD PMID:29031535 NCBI chr 2:198,683,168...198,686,971
Ensembl chr 2:198,683,159...198,686,974
JBrowse link
CMP-N-acetyl-beta-neuraminic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cmas cytidine monophosphate N-acetylneuraminic acid synthetase affects abundance ISO CMAS protein affects the abundance of Cytidine Monophosphate N-Acetylneuraminic Acid CTD PMID:27380425 NCBI chr 4:176,994,129...177,012,445
Ensembl chr 4:176,994,129...177,012,444
JBrowse link
D-gluconic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 multiple interactions EXP [gluconic acid co-treated with Deoxycholic Acid] results in increased expression of ALDH1A2 mRNA CTD PMID:16556975 NCBI chr 8:77,640,234...77,719,488
Ensembl chr 8:77,640,222...77,719,489
JBrowse link
G Arnt2 aryl hydrocarbon receptor nuclear translocator 2 multiple interactions EXP [gluconic acid co-treated with Deoxycholic Acid] results in increased expression of ARNT2 mRNA CTD PMID:16556975 NCBI chr 1:146,399,217...146,556,437
Ensembl chr 1:146,399,217...146,556,171
JBrowse link
G Atp6v1f ATPase H+ transporting V1 subunit F multiple interactions EXP [gluconic acid co-treated with Deoxycholic Acid] results in increased expression of ATP6V1F mRNA CTD PMID:16556975 NCBI chr 4:56,744,563...56,747,657
Ensembl chr 4:56,744,561...56,747,656
JBrowse link
G Casp3 caspase 3 multiple interactions ISO gluconic acid promotes the reaction [Zinc Sulfate inhibits the reaction [Aflatoxin B1 results in increased expression of CASP3 mRNA]] CTD PMID:27017951 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 multiple interactions ISO [gluconic acid co-treated with Zinc Sulfate] inhibits the reaction [Aflatoxin B1 results in increased expression of CASP8 mRNA] CTD PMID:27017951 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Cblb Cbl proto-oncogene B decreases expression EXP gluconic acid results in decreased expression of CBLB mRNA CTD PMID:16556975 NCBI chr11:51,037,383...51,202,761
Ensembl chr11:51,037,393...51,202,820
JBrowse link
G Clcn3 chloride voltage-gated channel 3 increases response to substance ISO CLCN3 protein results in increased susceptibility to gluconic acid CTD PMID:12843258 NCBI chr16:32,448,821...32,520,649
Ensembl chr16:32,449,116...32,519,148
JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 increases expression EXP gluconic acid results in increased expression of CRHR1 mRNA CTD PMID:16556975 NCBI chr10:92,191,473...92,233,662
Ensembl chr10:92,191,718...92,232,645
JBrowse link
G Csf1r colony stimulating factor 1 receptor multiple interactions EXP [gluconic acid co-treated with Deoxycholic Acid] results in increased expression of CSF1R mRNA CTD PMID:16556975 NCBI chr18:56,414,493...56,458,300
Ensembl chr18:56,414,488...56,458,300
JBrowse link
G Cyp4a8 cytochrome P450, family 4, subfamily a, polypeptide 8 multiple interactions EXP [gluconic acid co-treated with Deoxycholic Acid] results in increased expression of CYP4A8 mRNA CTD PMID:16556975 NCBI chr 5:133,978,953...134,008,255
Ensembl chr 5:133,978,954...134,008,255
JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase decreases expression EXP gluconic acid results in decreased expression of FYN mRNA CTD PMID:16556975 NCBI chr20:44,436,354...44,630,316
Ensembl chr20:44,436,403...44,630,317
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP [[gluconic acid results in increased abundance of Magnesium] co-treated with [Sodium Selenite results in increased abundance of Selenium]] inhibits the reaction [Dietary Fats results in increased expression of GPT protein] CTD PMID:30031400 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Grk2 G protein-coupled receptor kinase 2 multiple interactions EXP [gluconic acid co-treated with Deoxycholic Acid] results in increased expression of GRK2 mRNA CTD PMID:16556975 NCBI chr 1:219,536,220...219,544,329
Ensembl chr 1:219,536,220...219,544,328
JBrowse link
G Hcn4 hyperpolarization activated cyclic nucleotide-gated potassium channel 4 increases expression EXP gluconic acid results in increased expression of HCN4 mRNA CTD PMID:16556975 NCBI chr 8:63,599,907...63,637,327
Ensembl chr 8:63,600,663...63,639,654
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions EXP [[gluconic acid results in increased abundance of Magnesium] co-treated with [Sodium Selenite results in increased abundance of Selenium]] inhibits the reaction [Dietary Fats results in increased expression of HMGCR mRNA] CTD PMID:30031400 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Hoxa1 homeobox A1 multiple interactions EXP [gluconic acid co-treated with Deoxycholic Acid] results in increased expression of HOXA1 mRNA CTD PMID:16556975 NCBI chr 4:82,124,358...82,127,182
Ensembl chr 4:82,125,406...82,127,066
JBrowse link
G Kcnc1 potassium voltage-gated channel subfamily C member 1 multiple interactions EXP [gluconic acid co-treated with Deoxycholic Acid] results in increased expression of KCNC1 mRNA CTD PMID:16556975 NCBI chr 1:102,414,352...102,456,718
Ensembl chr 1:102,414,625...102,456,411
JBrowse link
G Kif3c kinesin family member 3C increases expression EXP gluconic acid results in increased expression of KIF3C mRNA CTD PMID:16556975 NCBI chr 6:27,768,943...27,815,611
Ensembl chr 6:27,768,943...27,815,611
JBrowse link
G Lcat lecithin cholesterol acyltransferase multiple interactions EXP [[gluconic acid results in increased abundance of Magnesium] co-treated with [Sodium Selenite results in increased abundance of Selenium]] inhibits the reaction [Dietary Fats results in decreased expression of LCAT mRNA] CTD PMID:30031400 NCBI chr19:37,913,333...37,916,799
Ensembl chr19:37,913,336...37,916,813
JBrowse link
G Lpl lipoprotein lipase multiple interactions EXP [gluconic acid co-treated with Deoxycholic Acid] results in increased expression of LPL mRNA CTD PMID:16556975 NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496
JBrowse link
G Mdh1 malate dehydrogenase 1 multiple interactions EXP [gluconic acid co-treated with Deoxycholic Acid] results in increased expression of MDH1 mRNA CTD PMID:16556975 NCBI chr14:106,378,349...106,393,642
Ensembl chr14:106,378,942...106,393,670
JBrowse link
G Mdh2 malate dehydrogenase 2 multiple interactions EXP [gluconic acid co-treated with Deoxycholic Acid] results in increased expression of MDH2 mRNA CTD PMID:16556975 NCBI chr12:23,941,451...23,954,406
Ensembl chr12:23,941,448...23,954,431
JBrowse link
G Mt1 metallothionein 1 multiple interactions ISO gluconic acid inhibits the reaction [Zinc Sulfate promotes the reaction [Aflatoxin B1 results in increased expression of MT1A mRNA]] CTD PMID:27017951 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
JBrowse link
G Mt2A metallothionein 2A multiple interactions ISO gluconic acid inhibits the reaction [Zinc Sulfate promotes the reaction [Aflatoxin B1 results in increased expression of MT2A mRNA]] CTD PMID:27017951 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Nr1d2 nuclear receptor subfamily 1, group D, member 2 multiple interactions EXP [gluconic acid co-treated with Deoxycholic Acid] results in increased expression of NR1D2 mRNA CTD PMID:16556975 NCBI chr15:8,730,871...8,757,165
Ensembl chr15:8,730,871...8,757,165
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 multiple interactions EXP [[gluconic acid results in increased abundance of Magnesium] co-treated with [Sodium Selenite results in increased abundance of Selenium]] affects the reaction [Dietary Fats results in increased expression of NR1H3 mRNA] CTD PMID:30031400 NCBI chr 3:80,004,130...80,014,197
Ensembl chr 3:80,004,130...80,012,750
JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 multiple interactions EXP [gluconic acid co-treated with Deoxycholic Acid] results in increased expression of PAK1 mRNA CTD PMID:16556975 NCBI chr 1:162,768,156...162,883,356
Ensembl chr 1:162,768,156...162,883,355
JBrowse link
G Pgap2 post-GPI attachment to proteins 2 multiple interactions EXP [gluconic acid co-treated with Deoxycholic Acid] results in increased expression of PGAP2 mRNA CTD PMID:16556975 NCBI chr 1:167,309,021...167,335,550
Ensembl chr 1:167,309,051...167,334,741
JBrowse link
G Prkar1a protein kinase cAMP-dependent type I regulatory subunit alpha multiple interactions EXP [gluconic acid co-treated with Deoxycholic Acid] results in increased expression of PRKAR1A mRNA CTD PMID:16556975 NCBI chr10:97,940,705...97,959,199
Ensembl chr10:97,940,705...97,957,336
JBrowse link
G Prkca protein kinase C, alpha multiple interactions EXP [gluconic acid co-treated with Deoxycholic Acid] results in increased expression of PRKCA mRNA CTD PMID:16556975 NCBI chr10:96,186,509...96,585,168
Ensembl chr10:96,191,133...96,584,947
JBrowse link
G Ptges prostaglandin E synthase multiple interactions EXP [gluconic acid co-treated with Deoxycholic Acid] results in increased expression of PTGES mRNA CTD PMID:16556975 NCBI chr 3:9,727,408...9,738,752
Ensembl chr 3:9,727,408...9,738,752
JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 multiple interactions EXP [gluconic acid co-treated with Deoxycholic Acid] results in increased expression of PTPN2 mRNA CTD PMID:16556975 NCBI chr18:63,415,298...63,489,240
Ensembl chr18:63,415,306...63,488,027
JBrowse link
G Rara retinoic acid receptor, alpha multiple interactions EXP [gluconic acid co-treated with Deoxycholic Acid] results in increased expression of RARA mRNA CTD PMID:16556975 NCBI chr10:86,838,819...86,884,224
Ensembl chr10:86,860,685...86,884,210
JBrowse link
G Rxrg retinoid X receptor gamma multiple interactions EXP [gluconic acid co-treated with Deoxycholic Acid] results in increased expression of RXRG mRNA CTD PMID:16556975 NCBI chr13:85,818,473...85,868,555
Ensembl chr13:85,818,427...85,868,552
JBrowse link
G Sema6c semaphorin 6C multiple interactions EXP [gluconic acid co-treated with Deoxycholic Acid] results in increased expression of SEMA6C mRNA CTD PMID:16556975 NCBI chr 2:196,330,777...196,347,218
Ensembl chr 2:196,334,626...196,344,008
JBrowse link
G Sirpa signal-regulatory protein alpha multiple interactions EXP [gluconic acid co-treated with Deoxycholic Acid] results in increased expression of SIRPA mRNA CTD PMID:16556975 NCBI chr 3:122,113,735...122,152,478
Ensembl chr 3:122,114,108...122,152,477
JBrowse link
G Slc15a2 solute carrier family 15 member 2 multiple interactions EXP [gluconic acid co-treated with Deoxycholic Acid] results in increased expression of SLC15A2 mRNA CTD PMID:16556975 NCBI chr11:66,932,664...66,961,708
Ensembl chr11:66,932,614...66,961,713
JBrowse link
G Slc22a12 solute carrier family 22 member 12 multiple interactions ISO gluconic acid promotes the reaction [SLC22A12 protein affects the transport of Uric Acid] CTD PMID:14747372 NCBI chr 1:221,910,787...221,919,277
Ensembl chr 1:221,910,767...221,919,301
JBrowse link
G Slc22a6 solute carrier family 22 member 6 multiple interactions ISO gluconic acid inhibits the reaction [SLC22A6 protein affects the transport of Uric Acid] CTD PMID:12472777 NCBI chr 1:224,824,809...224,833,284
Ensembl chr 1:224,824,799...224,833,259
JBrowse link
G Slc22a8 solute carrier family 22 member 8 multiple interactions EXP [gluconic acid co-treated with Deoxycholic Acid] results in increased expression of SLC22A8 mRNA CTD PMID:16556975 NCBI chr 1:224,799,444...224,818,482
Ensembl chr 1:224,800,252...224,818,482
JBrowse link
G Slc32a1 solute carrier family 32 member 1 decreases expression EXP gluconic acid results in decreased expression of SLC32A1 mRNA CTD PMID:16556975 NCBI chr 3:155,102,980...155,107,815
Ensembl chr 3:155,103,150...155,107,817
JBrowse link
G Slc6a8 solute carrier family 6 member 8 increases expression EXP gluconic acid results in increased expression of SLC6A8 mRNA CTD PMID:16556975 NCBI chr  X:157,129,987...157,139,321
Ensembl chr  X:157,129,987...157,139,291
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO [gluconic acid co-treated with Zinc Sulfate] promotes the reaction [Aflatoxin B1 results in increased expression of SOD1 mRNA] CTD PMID:27017951 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions EXP [[gluconic acid results in increased abundance of Magnesium] co-treated with [Sodium Selenite results in increased abundance of Selenium]] inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA] CTD PMID:30031400 NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009
JBrowse link
G Sstr3 somatostatin receptor 3 multiple interactions EXP [gluconic acid co-treated with Deoxycholic Acid] results in increased expression of SSTR3 mRNA CTD PMID:16556975 NCBI chr 7:119,760,881...119,768,082
Ensembl chr 7:119,760,888...119,768,082
JBrowse link
G Tas2r107 taste receptor, type 2, member 107 decreases expression EXP gluconic acid results in decreased expression of TAS2R10 mRNA CTD PMID:16556975 NCBI chr 4:165,773,200...165,774,126
Ensembl chr 4:165,773,200...165,774,126
JBrowse link
G Ube2i ubiquitin-conjugating enzyme E2I multiple interactions EXP [gluconic acid co-treated with Deoxycholic Acid] results in increased expression of UBE2I mRNA CTD PMID:16556975 NCBI chr10:14,618,615...14,639,274
Ensembl chr10:14,620,531...14,630,151
JBrowse link
G Vamp2 vesicle-associated membrane protein 2 multiple interactions EXP [gluconic acid co-treated with Deoxycholic Acid] results in increased expression of VAMP2 mRNA CTD PMID:16556975 NCBI chr10:55,675,171...55,679,405
Ensembl chr10:55,675,575...55,679,450
JBrowse link
G Vax2 ventral anterior homeobox 2 multiple interactions EXP [gluconic acid co-treated with Deoxycholic Acid] results in increased expression of VAX2 mRNA CTD PMID:16556975 NCBI chr 4:115,388,839...115,412,515
Ensembl chr 4:115,388,839...115,412,515
JBrowse link
G Vps52 VPS52 subunit of GARP complex increases expression EXP gluconic acid results in increased expression of VPS52 mRNA CTD PMID:16556975 NCBI chr20:5,431,997...5,441,736
Ensembl chr20:5,432,004...5,441,706
JBrowse link
G Wee1 WEE1 G2 checkpoint kinase increases expression EXP gluconic acid results in increased expression of WEE1 mRNA CTD PMID:16556975 NCBI chr 1:174,765,228...174,790,882
Ensembl chr 1:174,767,960...174,786,361
JBrowse link
D-glucurono-6,3-lactone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppargc1a PPARG coactivator 1 alpha increases expression ISO glucuronolactone results in increased expression of PPARGC1A mRNA CTD PMID:23056435 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
JBrowse link
D-glyceric acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 increases abundance
multiple interactions
ISO IDH2 protein mutant form results in increased abundance of glyceric acid
Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of glyceric acid]
CTD PMID:27469509 NCBI chr 1:141,874,354...141,893,674
Ensembl chr 1:141,866,283...141,893,705
JBrowse link
dehydroascorbic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 BCL2, apoptosis regulator multiple interactions
increases expression
ISO [Dehydroascorbic Acid co-treated with Lipopolysaccharides] results in increased expression of BCL2 protein
Dehydroascorbic Acid results in increased expression of BCL2 protein
CTD PMID:20166893 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Casp3 caspase 3 multiple interactions ISO Dehydroascorbic Acid promotes the reaction [arsenic trioxide results in increased activity of CASP3 protein]; Dehydroascorbic Acid promotes the reaction [Etoposide results in increased activity of CASP3 protein] CTD PMID:16951922 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cat catalase multiple interactions
increases expression
ISO [Dehydroascorbic Acid co-treated with Lipopolysaccharides] results in increased expression of CAT protein; Cytochalasin B inhibits the reaction [Dehydroascorbic Acid results in increased expression of CAT protein] CTD PMID:20166893 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cycs cytochrome c, somatic affects localization ISO Dehydroascorbic Acid affects the localization of CYCS protein CTD PMID:20166893 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO [Buthionine Sulfoximine co-treated with Dehydroascorbic Acid] promotes the reaction [cupric oxide results in increased expression of HMOX1 mRNA]; [monocrystalline iron oxide nanoparticle co-treated with Buthionine Sulfoximine co-treated with Dehydroascorbic Acid] results in increased expression of HMOX1 mRNA; [monocrystalline iron oxide nanoparticle co-treated with Dehydroascorbic Acid] results in increased expression of HMOX1 mRNA; Dehydroascorbic Acid promotes the reaction [Copper Sulfate results in increased expression of HMOX1 mRNA]; Dehydroascorbic Acid promotes the reaction [cupric oxide results in increased expression of HMOX1 mRNA] CTD PMID:19683516 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO
EXP
Dehydroascorbic Acid inhibits the reaction [IL1B results in increased chemical synthesis of 8-epi-prostaglandin F2alpha]
Dehydroascorbic Acid inhibits the reaction [Blood Glucose affects the expression of IL1B protein]
CTD PMID:15737438, PMID:16529823 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP Dehydroascorbic Acid inhibits the reaction [Blood Glucose affects the expression of PTGS2 protein] CTD PMID:15737438 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Slc2a1 solute carrier family 2 member 1 decreases transport
affects transport
affects uptake
ISO
EXP
SLC2A1 protein mutant form results in decreased transport of Dehydroascorbic Acid
SLC2A1 protein affects the transport of Dehydroascorbic Acid
SLC2A1 mRNA affects the uptake of Dehydroascorbic Acid
CTD PMID:11603379, PMID:15590689, PMID:16142743 NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897
JBrowse link
G Slc2a2 solute carrier family 2 member 2 increases uptake ISO SLC2A2 protein results in increased uptake of Dehydroascorbic Acid CTD PMID:23396969 NCBI chr 2:114,413,427...114,445,418
Ensembl chr 2:114,413,410...114,445,395
JBrowse link
G Slc2a3 solute carrier family 2 member 3 affects transport ISO SLC2A3 protein affects the transport of Dehydroascorbic Acid CTD PMID:15590689 NCBI chr 4:155,549,991...155,626,018
Ensembl chr 4:155,408,233...155,631,856
JBrowse link
G Slc2a8 solute carrier family 2 member 8 increases uptake EXP
ISO
SLC2A8 protein results in increased uptake of Dehydroascorbic Acid CTD PMID:23396969 NCBI chr 3:12,020,227...12,029,920
Ensembl chr 3:12,020,229...12,029,877
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
increases expression
ISO [Dehydroascorbic Acid co-treated with Lipopolysaccharides] results in increased expression of SOD2 protein; Cytochalasin B inhibits the reaction [Dehydroascorbic Acid results in increased expression of SOD2 protein] CTD PMID:20166893 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
estriol 16-O-(beta-D-glucuronide) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions EXP estriol-16 alpha-(beta-D-glucuronide) inhibits the reaction [ABCB1 results in increased transport of estradiol-17 beta-glucuronide] CTD PMID:9794924 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
estriol 3-O-(beta-D-glucuronide) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kl Klotho multiple interactions
increases hydrolysis
ISO estriol 3-glucuronide inhibits the reaction [KL protein results in increased hydrolysis of Glucuronides]
KL protein results in increased hydrolysis of estriol 3-glucuronide
CTD PMID:14701853 NCBI chr12:942,974...987,206
Ensembl chr12:943,006...987,551
JBrowse link
estrone 3-O-(beta-D-glucuronide) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kl Klotho increases hydrolysis
multiple interactions
ISO KL protein results in increased hydrolysis of estrone-3-glucuronide
estrone-3-glucuronide inhibits the reaction [KL protein results in increased hydrolysis of Glucuronides]
CTD PMID:14701853 NCBI chr12:942,974...987,206
Ensembl chr12:943,006...987,551
JBrowse link
galactaric acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lepr leptin receptor affects abundance ISO LEPR affects the abundance of galactaric acid CTD PMID:20567778 NCBI chr 5:120,503,475...120,682,281
Ensembl chr 5:120,564,645...120,682,221
JBrowse link
glucaric acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ago2 argonaute RISC catalytic component 2 multiple interactions ISO Glucaric Acid affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of AGO2 mRNA]; Glucaric Acid affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of AGO2 protein] CTD PMID:24792773 NCBI chr 7:114,339,607...114,377,277
Ensembl chr 7:114,339,434...114,380,613
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 multiple interactions ISO [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of APAF1 mRNA]; [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of APAF1 protein]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of APAF1 mRNA]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of APAF1 protein] CTD PMID:25478867 NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of BAX mRNA]; [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of BAX protein]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of BAX mRNA]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of BAX protein] CTD PMID:25478867 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of BCL2 mRNA]; [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of BCL2 protein]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of BCL2 mRNA]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of BCL2 protein] CTD PMID:25478867 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bmi1 BMI1 proto-oncogene, polycomb ring finger multiple interactions ISO Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of BMI1 mRNA]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of BMI1 protein] CTD PMID:24792773 NCBI chr17:85,360,439...85,370,283
Ensembl chr17:85,364,483...85,368,208
JBrowse link
G Casp3 caspase 3 multiple interactions ISO [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased activity of CASP3 protein]; [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CASP3 mRNA]; [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CASP3 protein]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased activity of CASP3 protein]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CASP3 mRNA]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CASP3 protein] CTD PMID:25478867 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp9 caspase 9 multiple interactions ISO [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased activity of CASP9 protein]; [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CASP9 mRNA]; [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CASP9 protein]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased activity of CASP9 protein]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CASP9 mRNA]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CASP9 protein] CTD PMID:25478867 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CDKN1A mRNA]; [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CDKN1A protein]; [Plant Extracts co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CDKN1A mRNA]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CDKN1A mRNA]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CDKN1A protein] CTD PMID:20103723, PMID:25478867 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A multiple interactions ISO Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CDKN2A mRNA]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased expression of CDKN2A protein]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased methylation of CDKN2A promoter] CTD PMID:24792773 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO [Glucaric Acid co-treated with Plant Extracts] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]; [Glucaric Acid co-treated with Resveratrol] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA] CTD PMID:20103723 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Dicer1 dicer 1 ribonuclease III multiple interactions ISO Glucaric Acid affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of DICER1 mRNA]; Glucaric Acid affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of DICER1 protein] CTD PMID:24792773 NCBI chr 6:128,388,084...128,453,234
Ensembl chr 6:128,388,053...128,434,183
JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions ISO Glucaric Acid affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of DNMT1 mRNA]; Glucaric Acid affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of DNMT1 protein] CTD PMID:24792773 NCBI chr 8:21,922,515...21,968,495
Ensembl chr 8:21,922,515...21,968,495
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Glucaric Acid co-treated with Plant Extracts] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of FOS mRNA]; [Glucaric Acid co-treated with resveratrol] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of FOS mRNA] CTD PMID:20103723 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Hdac1 histone deacetylase 1 multiple interactions ISO Glucaric Acid affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of HDAC1 mRNA]; Glucaric Acid affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of HDAC1 protein] CTD PMID:24792773 NCBI chr 5:147,716,664...147,743,723
Ensembl chr 5:147,716,664...147,743,723
JBrowse link
G Hras HRas proto-oncogene, GTPase multiple interactions ISO [Glucaric Acid co-treated with Plant Extracts] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased mutagenesis of HRAS gene]; [Glucaric Acid co-treated with resveratrol] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased mutagenesis of HRAS gene] CTD PMID:20103723 NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
JBrowse link
G Il6 interleukin 6 multiple interactions ISO [Glucaric Acid co-treated with resveratrol] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of IL6 mRNA]; [Glucaric Acid co-treated with ursolic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of IL6 mRNA]; Glucaric Acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of IL6 mRNA] CTD PMID:23835587 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Glucaric Acid co-treated with Resveratrol] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of JUN protein]; [Glucaric Acid co-treated with ursolic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of JUN protein]; Glucaric Acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of JUN protein] CTD PMID:23835587 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Mir3545 microRNA 3545 multiple interactions ISO Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene affects the expression of MIR203 mRNA]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased methylation of MIR203 promoter] CTD PMID:24792773 NCBI chr 6:136,704,947...136,705,061
Ensembl chr 6:136,704,947...136,705,061
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions ISO Glucaric Acid affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of MYC mRNA]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of MYC protein] CTD PMID:24792773 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO [ursolic acid co-treated with Glucaric Acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of NFKB1 protein] CTD PMID:23835587 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO [Glucaric Acid co-treated with Plant Extracts] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of PCNA mRNA] CTD PMID:20103723 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO [resveratrol co-treated with Glucaric Acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of PTGS2 mRNA]; [ursolic acid co-treated with Glucaric Acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of PTGS2 mRNA]; Glucaric Acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of PTGS2 mRNA] CTD PMID:23835587 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of TRP53 mRNA alternative form]; [Butyric Acid co-treated with Niacinamide co-treated with Glucaric Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of TRP53 protein]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of TRP53 mRNA alternative form]; Glucaric Acid inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of TRP53 protein] CTD PMID:25478867 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
glucuronic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1a1 aldo-keto reductase family 1 member A1 increases reduction ISO
EXP
AKR1A1 protein results in increased reduction of Glucuronic Acid CTD PMID:10510318, PMID:29763686 NCBI chr 5:135,482,068...135,498,693
Ensembl chr 5:135,482,068...135,498,822
JBrowse link
glyceric acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 multiple interactions
increases abundance
ISO Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of glyceric acid] CTD PMID:27469509 NCBI chr 1:141,874,354...141,893,674
Ensembl chr 1:141,866,283...141,893,705
JBrowse link
glycyrrhizinic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions
decreases activity
ISO Glycyrrhizic Acid inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
Glycyrrhizic Acid results in decreased activity of ABCB11 protein
CTD PMID:24014644 NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 multiple interactions ISO Glycyrrhizic Acid affects the reaction [1-Naphthylisothiocyanate affects the expression of ABCC3 mRNA] CTD PMID:28549656 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 multiple interactions ISO Glycyrrhizic Acid affects the reaction [1-Naphthylisothiocyanate affects the expression of ACAT2 mRNA] CTD PMID:28549656 NCBI chr 1:47,972,399...47,992,654
Ensembl chr 1:47,972,399...47,992,653
JBrowse link
G Ache acetylcholinesterase multiple interactions EXP Glycyrrhizic Acid inhibits the reaction [Fusaric Acid results in decreased expression of ACHE protein] CTD PMID:31150628 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions EXP Glycyrrhizic Acid inhibits the reaction [Doxorubicin results in increased phosphorylation of AKT1 protein] CTD PMID:32525084 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Alb albumin multiple interactions ISO ALB protein binds to and affects the transport of Glycyrrhizic Acid CTD PMID:8831264 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Aqp2 aquaporin 2 multiple interactions EXP Glycyrrhizic Acid inhibits the reaction [Gentamicins results in decreased expression of AQP2 protein] CTD PMID:12969435 NCBI chr 7:141,237,802...141,242,837
Ensembl chr 7:141,237,768...141,245,165
JBrowse link
G Aqp5 aquaporin 5 multiple interactions ISO Glycyrrhizic Acid inhibits the reaction [Histamine results in decreased expression of AQP5 protein] CTD PMID:29452068 NCBI chr 7:141,249,044...141,252,576
Ensembl chr 7:141,249,044...141,252,578
JBrowse link
G Ar androgen receptor multiple interactions
affects localization
ISO Glycyrrhizic Acid binds to and results in increased activity of AR protein
Glycyrrhizic Acid affects the localization of AR protein
CTD PMID:28478275 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions EXP Glycyrrhizic Acid inhibits the reaction [Fusaric Acid results in decreased expression of BDNF protein] CTD PMID:31150628 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Casp2 caspase 2 multiple interactions EXP Glycyrrhizic Acid inhibits the reaction [Benzo(a)pyrene results in increased activity of CASP2 protein] CTD PMID:22051199 NCBI chr 4:71,652,358...71,670,228
Ensembl chr 4:71,652,354...71,670,239
JBrowse link
G Casp3 caspase 3 multiple interactions EXP Glycyrrhizic Acid inhibits the reaction [Benzo(a)pyrene results in increased activity of CASP3 protein]; Glycyrrhizic Acid inhibits the reaction [Fusaric Acid results in decreased expression of CASP3 protein] CTD PMID:22051199, PMID:31150628 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp6 caspase 6 multiple interactions EXP Glycyrrhizic Acid inhibits the reaction [Benzo(a)pyrene results in increased activity of CASP6 protein] CTD PMID:22051199 NCBI chr 2:235,341,326...235,353,715
Ensembl chr 2:235,341,365...235,353,967
Ensembl chr 2:235,341,365...235,353,967
JBrowse link
G Casp8 caspase 8 multiple interactions EXP Glycyrrhizic Acid inhibits the reaction [Benzo(a)pyrene results in increased activity of CASP8 protein] CTD PMID:22051199 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 multiple interactions EXP Glycyrrhizic Acid inhibits the reaction [Benzo(a)pyrene results in increased activity of CASP9 protein] CTD PMID:22051199 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO Glycyrrhizic Acid inhibits the reaction [Cyclosporine results in increased expression of CCL2 mRNA] CTD PMID:27585667 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO Glycyrrhizic Acid inhibits the reaction [Histamine results in decreased phosphorylation of CREB1 protein] CTD PMID:29452068 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 decreases expression EXP Glycyrrhizic Acid results in decreased expression of CYP11B2 mRNA CTD PMID:10474021, PMID:11798659 NCBI chr 7:116,155,928...116,161,781
Ensembl chr 7:116,156,219...116,255,167
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression
multiple interactions
ISO Glycyrrhizic Acid results in decreased expression of CYP7A1 mRNA
Glycyrrhizic Acid inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of CYP7A1 mRNA]
CTD PMID:22982774, PMID:28549656 NCBI chr 5:19,358,734...19,368,431
Ensembl chr 5:19,358,734...19,368,431
JBrowse link
G Ephx2 epoxide hydrolase 2 multiple interactions EXP Glycyrrhizic Acid inhibits the reaction [Benzo(a)pyrene results in decreased activity of EPHX2 protein] CTD PMID:22051199 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP
ISO
Glycyrrhizic Acid inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with BCG Vaccine] results in increased activity of GPT protein]
Glycyrrhizic Acid inhibits the reaction [1-Naphthylisothiocyanate results in increased activity of GPT protein]
CTD PMID:19196740, PMID:28549656 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Hmgb1 high mobility group box 1 decreases secretion
multiple interactions
decreases activity
ISO
EXP
Glycyrrhizic Acid results in decreased secretion of HMGB1 protein
Glycyrrhizic Acid inhibits the reaction [Doxorubicin results in increased expression of HMGB1 protein]
Glycyrrhizic Acid results in decreased activity of HMGB1 protein
CTD PMID:27585667, PMID:27689324, PMID:27783111, PMID:32525084 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO Glycyrrhizic Acid promotes the reaction [Carbon Tetrachloride results in increased expression of HMOX1 mRNA]; Glycyrrhizic Acid promotes the reaction [Carbon Tetrachloride results in increased expression of HMOX1 protein] CTD PMID:17917259 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 decreases expression EXP Glycyrrhizic Acid results in decreased expression of HSD11B2 mRNA CTD PMID:10474021, PMID:11798659 NCBI chr19:37,476,083...37,481,326
Ensembl chr19:37,476,095...37,481,307
JBrowse link
G Ifng interferon gamma affects expression ISO Glycyrrhizic Acid affects the expression of IFNG mRNA CTD PMID:16945185 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il12a interleukin 12A multiple interactions ISO [Glycyrrhizic Acid co-treated with Lipopolysaccharides] results in increased expression of [IL12A protein binds to IL12B protein]; [Glycyrrhizic Acid co-treated with Lipopolysaccharides] results in increased expression of IL12A mRNA CTD PMID:11412311 NCBI chr 2:165,076,945...165,083,996
Ensembl chr 2:165,076,607...165,084,318
JBrowse link
G Il12b interleukin 12B multiple interactions ISO [Glycyrrhizic Acid co-treated with Lipopolysaccharides] results in increased expression of [IL12A protein binds to IL12B protein]; [Glycyrrhizic Acid co-treated with Lipopolysaccharides] results in increased expression of IL12B mRNA; [Glycyrrhizic Acid co-treated with Lipopolysaccharides] results in increased expression of IL12B protein CTD PMID:11412311 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
JBrowse link
G Il6 interleukin 6 multiple interactions ISO
EXP
Glycyrrhizic Acid inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL6 protein]
Glycyrrhizic Acid inhibits the reaction [Histamine results in increased expression of IL6 mRNA]; Glycyrrhizic Acid inhibits the reaction [Histamine results in increased secretion of IL6 protein]
Glycyrrhizic Acid inhibits the reaction [Chlorpyrifos results in increased expression of IL6 mRNA]; Glycyrrhizic Acid inhibits the reaction [Chlorpyrifos results in increased expression of IL6 protein]
CTD PMID:21644799, PMID:26524701, PMID:29452068 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions EXP [Glycyrrhizic Acid co-treated with bafilomycin A1] results in increased lipidation of MAP1LC3B protein; Glycyrrhizic Acid inhibits the reaction [Doxorubicin results in increased expression of and results in increased lipidation of MAP1LC3B protein]; Glycyrrhizic Acid inhibits the reaction [Doxorubicin results in increased lipidation of MAP1LC3B protein] CTD PMID:32525084 NCBI chr19:53,635,449...53,643,970
Ensembl chr19:53,629,779...53,646,058
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO Glycyrrhizic Acid inhibits the reaction [Picryl Chloride results in increased secretion of MMP2 protein] CTD PMID:16945185 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions EXP Glycyrrhizic Acid inhibits the reaction [Doxorubicin results in increased phosphorylation of MTOR protein] CTD PMID:32525084 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Mttp microsomal triglyceride transfer protein multiple interactions ISO Glycyrrhizic Acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of MTTP mRNA] CTD PMID:28549656 NCBI chr 2:243,366,181...243,407,608
Ensembl chr 2:243,366,181...243,407,608
JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming multiple interactions ISO Glycyrrhizic Acid inhibits the reaction [Histamine results in increased expression of MUC5AC mRNA]; Glycyrrhizic Acid inhibits the reaction [Histamine results in increased secretion of MUC5AC protein] CTD PMID:29452068 NCBI chr 1:214,725,482...214,756,653 JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO [Glycyrrhizic Acid co-treated with Lipopolysaccharides] results in increased activity of [NFKB1 protein binds to RELA protein] CTD PMID:11412311 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO Glycyrrhizic Acid inhibits the reaction [Histamine results in increased phosphorylation of NFKBIA protein] CTD PMID:29452068 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO Glycyrrhizic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of NOS2 mRNA]; Glycyrrhizic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of NOS2 protein]; Glycyrrhizic Acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of NOS2 mRNA]; Glycyrrhizic Acid inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 mRNA]; Glycyrrhizic Acid inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 protein] CTD PMID:17917259, PMID:21644799, PMID:23373965 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Npc1l1 NPC1 like intracellular cholesterol transporter 1 multiple interactions ISO Glycyrrhizic Acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of NPC1L1 mRNA] CTD PMID:28549656 NCBI chr14:86,345,946...86,560,694
Ensembl chr14:86,345,953...86,560,694
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 increases expression ISO Glycyrrhizic Acid results in increased expression of NR0B2 mRNA CTD PMID:22982774 NCBI chr 5:151,776,004...151,779,319
Ensembl chr 5:151,776,004...151,779,319
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity
multiple interactions
ISO Glycyrrhizic Acid results in increased activity of NR1I2 protein
NR1I2 protein affects the reaction [Glycyrrhizic Acid results in increased expression of CYP3A4 mRNA]
CTD PMID:22982774 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta decreases activity ISO Glycyrrhizic Acid results in decreased activity of PIK3CD protein CTD PMID:21644799 NCBI chr 5:166,602,053...166,628,028
Ensembl chr 5:166,602,053...166,628,028
JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma decreases activity ISO Glycyrrhizic Acid results in decreased activity of PIK3CG protein CTD PMID:21644799 NCBI chr 6:51,465,696...51,501,234
Ensembl chr 6:51,465,908...51,498,337
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO Glycyrrhizic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of PTGS2 mRNA]; Glycyrrhizic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of PTGS2 protein]; Glycyrrhizic Acid inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of PTGS2 mRNA]; Glycyrrhizic Acid inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of PTGS2 protein] CTD PMID:17917259, PMID:21644799 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO
EXP
[Glycyrrhizic Acid co-treated with Lipopolysaccharides] results in increased activity of [NFKB1 protein binds to RELA protein]
Glycyrrhizic Acid inhibits the reaction [Histamine results in increased phosphorylation of RELA protein]
Glycyrrhizic Acid inhibits the reaction [Benzo(a)pyrene affects the localization of RELA protein]; Glycyrrhizic Acid inhibits the reaction [Chlorpyrifos results in increased phosphorylation of RELA protein]
CTD PMID:11412311, PMID:22051199, PMID:26524701, PMID:29452068 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Ren renin decreases activity ISO Glycyrrhizic Acid results in decreased activity of REN protein CTD PMID:20460744 NCBI chr13:50,502,724...50,513,953
Ensembl chr13:50,502,724...50,514,151
JBrowse link
G Sirt1 sirtuin 1 multiple interactions EXP Glycyrrhizic Acid inhibits the reaction [Glucose results in decreased expression of SIRT1 protein] CTD PMID:25162824 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Glycyrrhizic Acid inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
G Slc51b solute carrier family 51 subunit beta multiple interactions ISO Glycyrrhizic Acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of SLC51B mRNA] CTD PMID:28549656 NCBI chr 8:70,930,196...70,938,559
Ensembl chr 8:70,930,347...70,932,986
JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 multiple interactions ISO Glycyrrhizic Acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of SLCO1A4 mRNA] CTD PMID:28549656 NCBI chr 4:175,969,549...176,026,227
Ensembl chr 4:175,969,549...176,026,163
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions EXP Glycyrrhizic Acid inhibits the reaction [Glucose results in decreased expression of SOD2 protein] CTD PMID:25162824 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sqstm1 sequestosome 1 multiple interactions EXP Glycyrrhizic Acid affects the reaction [Doxorubicin results in increased expression of SQSTM1 protein] CTD PMID:32525084 NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP Glycyrrhizic Acid inhibits the reaction [Glucose results in increased expression of TGFB1 protein] CTD PMID:25162824 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tjp1 tight junction protein 1 multiple interactions ISO Glycyrrhizic Acid inhibits the reaction [Glucose results in decreased expression of TJP1 protein]; Glycyrrhizic Acid inhibits the reaction [Palmitic Acid results in decreased expression of TJP1 protein] CTD PMID:27689324, PMID:27783111 NCBI chr 1:126,146,489...126,515,359
Ensembl chr 1:126,146,489...126,227,469
JBrowse link
G Tjp2 tight junction protein 2 multiple interactions ISO Glycyrrhizic Acid inhibits the reaction [Glucose results in decreased expression of TJP2 protein]; Glycyrrhizic Acid inhibits the reaction [Palmitic Acid results in decreased expression of TJP2 protein] CTD PMID:27689324, PMID:27783111 NCBI chr 1:241,945,816...242,084,044
Ensembl chr 1:241,945,841...242,083,484
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP
Glycyrrhizic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF mRNA]; Glycyrrhizic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF protein]; Glycyrrhizic Acid inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNF protein]
Glycyrrhizic Acid inhibits the reaction [Chlorpyrifos results in increased expression of TNF mRNA]; Glycyrrhizic Acid inhibits the reaction [Chlorpyrifos results in increased expression of TNF protein]
CTD PMID:17917259, PMID:21644799, PMID:26524701 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
L-ascorbic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aars1 alanyl-tRNA synthetase 1 decreases expression ISO Ascorbic Acid results in decreased expression of AARS1 mRNA CTD PMID:19197388 NCBI chr19:43,193,264...43,215,281
Ensembl chr19:43,193,257...43,215,281
JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 multiple interactions ISO [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of ABCA1 mRNA; [Bexarotene co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 protein; [diazepinylbenzoic acid co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in decreased expression of ABCA1 mRNA; [LG 100268 co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA; [Quercetin co-treated with Ascorbic Acid] results in decreased expression of ABCA1 mRNA; [Rosiglitazone co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 protein; [TO-901317 co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA; [tributyltin co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA; [tributyltin co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 protein; diazepinylbenzoic acid inhibits the reaction [[LG 100268 co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA]; diazepinylbenzoic acid inhibits the reaction [[tributyltin co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA] CTD PMID:17639512, PMID:25932594 NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO Ascorbic Acid inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCB1 mRNA] CTD PMID:22914566 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions ISO Ascorbic Acid inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCC1 mRNA] CTD PMID:22914566 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions ISO
EXP
Ascorbic Acid inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCC2 mRNA]; Ascorbic Acid inhibits the reaction [4-hydroxy-2-nonenal inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]]; Ascorbic Acid promotes the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]
Ascorbic Acid inhibits the reaction [Fructose results in decreased expression of ABCC2 mRNA]; Ascorbic Acid inhibits the reaction [Fructose results in decreased expression of ABCC2 protein]
CTD PMID:19326901, PMID:22914566, PMID:31005848 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Acan aggrecan multiple interactions ISO [TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of ACAN mRNA; IL1B protein inhibits the reaction [[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of ACAN mRNA]; Resveratrol inhibits the reaction [IL1B protein inhibits the reaction [[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of ACAN mRNA]] CTD PMID:26526931 NCBI chr 1:140,762,758...140,824,441
Ensembl chr 1:140,762,758...140,824,441
JBrowse link
G Ace angiotensin I converting enzyme multiple interactions ISO Ascorbic Acid inhibits the reaction [epigallocatechin gallate results in decreased activity of ACE protein] CTD PMID:28544013 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Ace2 angiotensin I converting enzyme 2 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in decreased expression of ACE2 mRNA CTD PMID:17639512 NCBI chr  X:32,050,734...32,095,860
Ensembl chr  X:32,049,931...32,096,016
JBrowse link
G Ache acetylcholinesterase decreases activity
multiple interactions
increases activity
ISO
EXP
Ascorbic Acid results in decreased activity of ACHE protein
[Dexamethasone co-treated with Ascorbic Acid] results in increased expression of ACHE mRNA; [Dexamethasone co-treated with Ascorbic Acid] results in increased expression of and results in increased activity of ACHE protein; [Zinc co-treated with Vitamin E co-treated with Ascorbic Acid] inhibits the reaction [sodium arsenite results in increased activity of ACHE protein]; Ascorbic Acid inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased activity of ACHE protein]; Ascorbic Acid inhibits the reaction [Scopolamine results in decreased activity of ACHE protein]
Ascorbic Acid inhibits the reaction [Glucose results in decreased activity of ACHE protein]
Ascorbic Acid results in increased activity of ACHE protein
[Resveratrol co-treated with Ascorbic Acid co-treated with Thioctic Acid co-treated with Vitamin E] results in increased activity of ACHE protein; Hexachlorocyclohexane inhibits the reaction [[Resveratrol co-treated with Ascorbic Acid co-treated with Thioctic Acid co-treated with Vitamin E] results in increased activity of ACHE protein]
CTD PMID:11814146, PMID:16248992, PMID:16822217, PMID:19703495, PMID:20663516, PMID:23619517, PMID:26163454, PMID:27019979 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 decreases expression EXP Ascorbic Acid results in decreased expression of ACSL4 mRNA CTD PMID:15372504 NCBI chr  X:113,596,247...113,660,024
Ensembl chr  X:113,596,239...113,659,944
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions EXP
ISO
[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of ACTA2 protein
[Ascorbic Acid co-treated with TGFB1 protein] results in increased expression of ACTA2 mRNA; [Ascorbic Acid co-treated with TGFB1 protein] results in increased expression of ACTA2 protein; [Mercaptoethanol co-treated with Ascorbic Acid] results in increased expression of ACTA2 protein; Ascorbic Acid promotes the reaction [Quartz results in increased expression of ACTA2 mRNA]
CTD PMID:7593635, PMID:17053324, PMID:18607632, PMID:27381660 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Adcy6 adenylate cyclase 6 decreases expression ISO Ascorbic Acid results in decreased expression of ADCY6 mRNA CTD PMID:17303424 NCBI chr 7:140,270,678...140,291,722
Ensembl chr 7:140,270,692...140,291,620
JBrowse link
G Adgrl1 adhesion G protein-coupled receptor L1 decreases expression EXP Ascorbic Acid results in decreased expression of ADGRL1 mRNA CTD PMID:15372504 NCBI chr19:25,029,037...25,069,146
Ensembl chr19:25,029,037...25,069,142
JBrowse link
G Ago2 argonaute RISC catalytic component 2 decreases expression EXP Ascorbic Acid results in decreased expression of AGO2 mRNA CTD PMID:15372504 NCBI chr 7:114,339,607...114,377,277
Ensembl chr 7:114,339,434...114,380,613
JBrowse link
G Agt angiotensinogen multiple interactions EXP
ISO
Ascorbic Acid inhibits the reaction [AGT protein modified form results in decreased hydroxylation of HIF1A protein]; Ascorbic Acid inhibits the reaction [AGT protein modified form results in increased expression of TIMP1 protein]
[Ascorbic Acid co-treated with Copper Sulfate] promotes the reaction [AGT protein modified form results in increased chemical synthesis of [4-hydroxy-2-nonenal binds to AGT protein modified form]]; [Ascorbic Acid co-treated with Copper Sulfate] promotes the reaction [AGT protein modified form results in increased chemical synthesis of [pyruvamide binds to AGT protein modified form]]; Ascorbic Acid promotes the reaction [linoleic acid hydroperoxide results in increased lipidation of AGT protein modified form]; Losartan inhibits the reaction [[AGT protein modified form co-treated with Ascorbic Acid co-treated with Copper Sulfate] results in increased chemical synthesis of [4-hydroxy-2-nonenal binds to AGT protein modified form]]; Losartan inhibits the reaction [[AGT protein modified form co-treated with Ascorbic Acid co-treated with Copper Sulfate] results in increased chemical synthesis of [pyruvamide binds to AGT protein modified form]]
CTD PMID:20881940, PMID:26111765, PMID:31144504 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Ak4 adenylate kinase 4 decreases expression ISO Ascorbic Acid results in decreased expression of AK4 mRNA CTD PMID:15305145 NCBI chr 5:120,250,318...120,309,153
Ensembl chr 5:120,250,616...120,305,897
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B increases reduction ISO Ascorbic Acid results in increased reduction of AKR1B1 protein modified form CTD PMID:19061876 NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases expression ISO Ascorbic Acid results in increased expression of AKR1B10 mRNA CTD PMID:26198647 NCBI chr 4:61,813,265...61,830,371
Ensembl chr 4:61,771,970...61,828,657
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 increases expression ISO Ascorbic Acid results in increased expression of AKR1C2 mRNA CTD PMID:26198647 NCBI chr17:69,388,337...69,435,160
Ensembl chr17:69,388,335...69,404,341
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions EXP [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in decreased phosphorylation of AKT1 protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased phosphorylation of AKT1 protein] CTD PMID:21262251, PMID:21911000 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Akt2 AKT serine/threonine kinase 2 affects expression ISO Ascorbic Acid affects the expression of AKT2 mRNA CTD PMID:30597948 NCBI chr 1:84,400,939...84,451,223
Ensembl chr 1:84,411,726...84,450,162
JBrowse link
G Alas1 5'-aminolevulinate synthase 1 multiple interactions ISO [Ascorbic Acid co-treated with 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid] inhibits the reaction [Griseofulvin results in increased activity of ALAS1 protein]; Ascorbic Acid inhibits the reaction [Griseofulvin results in increased activity of ALAS1 protein] CTD PMID:24523661 NCBI chr 8:114,927,704...114,941,038
Ensembl chr 8:114,927,722...114,940,177
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member multiple interactions ISO ALDH2 protein affects the reaction [Ascorbic Acid deficiency results in decreased susceptibility to Nitroglycerin] CTD PMID:23194305 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
G Alpi alkaline phosphatase, intestinal multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in decreased expression of ALPI mRNA CTD PMID:17639512 NCBI chr 9:94,197,616...94,201,910
Ensembl chr 9:94,197,618...94,201,084
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions
increases expression
ISO [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of ALPL mRNA; EZH2 protein inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of ALPL mRNA]
[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of ALPL mRNA; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of ALPL mRNA]
Ascorbic Acid results in increased expression of ALPL mRNA
CTD PMID:26424790, PMID:26492236, PMID:28105418 NCBI chr 5:156,086,496...156,141,513
Ensembl chr 5:156,086,497...156,141,537
JBrowse link
G Anpep alanyl aminopeptidase, membrane multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in decreased expression of ANPEP mRNA CTD PMID:17639512 NCBI chr 1:141,561,364...141,604,249
Ensembl chr 1:141,561,334...141,604,273
JBrowse link
G Anxa1 annexin A1 multiple interactions
increases expression
ISO
EXP
[Quercetin co-treated with Ascorbic Acid] results in increased expression of ANXA1 mRNA
Ascorbic Acid results in increased expression of ANXA1 mRNA
CTD PMID:15372504, PMID:17639512 NCBI chr 1:237,893,983...237,910,002
Ensembl chr 1:237,893,966...237,910,012
JBrowse link
G Anxa5 annexin A5 multiple interactions
increases expression
ISO
EXP
[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of ANXA5 mRNA
Ascorbic Acid results in increased expression of ANXA5 mRNA
Ascorbic Acid results in increased expression of ANXA5 protein
CTD PMID:15372504, PMID:17917374, PMID:19224539 NCBI chr 2:123,162,477...123,194,730
Ensembl chr 2:123,162,461...123,193,130
JBrowse link
G Apoa1 apolipoprotein A1 decreases expression
decreases activity
ISO
EXP
Ascorbic Acid results in decreased expression of APOA1 mRNA; Ascorbic Acid results in decreased expression of APOA1 protein
Ascorbic Acid results in decreased activity of APOA1 promoter
CTD PMID:16423621 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Apob apolipoprotein B multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in decreased expression of APOB mRNA; Ascorbic Acid promotes the reaction [Flavonoids inhibits the reaction [Copper results in increased oxidation of APOB protein]]; Ascorbic Acid promotes the reaction [Quercetin inhibits the reaction [Copper results in increased oxidation of APOB protein]] CTD PMID:17475462, PMID:17639512 NCBI chr 6:33,176,826...33,216,381
Ensembl chr 6:33,176,778...33,224,997
JBrowse link
G Apoe apolipoprotein E increases expression EXP Ascorbic Acid results in increased expression of APOE mRNA CTD PMID:15372504 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Apom apolipoprotein M multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in decreased expression of APOM mRNA CTD PMID:17639512 NCBI chr20:5,120,473...5,123,073
Ensembl chr20:5,120,474...5,123,073
JBrowse link
G App amyloid beta precursor protein multiple interactions
decreases abundance
increases oxidation
EXP
ISO
Ascorbic Acid inhibits the reaction [APP protein modified form results in increased abundance of Reactive Oxygen Species]; resveratrol inhibits the reaction [APP protein modified form results in decreased abundance of Ascorbic Acid]
APP protein modified form results in increased oxidation of Ascorbic Acid
[[[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of phosphatidylcholine hydroperoxide] which results in increased chemical synthesis of 4-hydroxy-2-nonenal; [[[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of Phosphatidylcholines] which results in increased chemical synthesis of phosphatidylcholine hydroperoxide; [[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of phosphatidylcholine hydroperoxide; [[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of Phosphatidylcholines; [APP protein modified form binds to Copper] which results in increased oxidation of Ascorbic Acid; [APP protein modified form inhibits the reaction [[Copper co-treated with Ascorbic Acid] results in increased oxidation of phosphatidylcholine hydroperoxide]] which results in increased chemical synthesis of 4-hydroxy-2-nonenal; APP protein inhibits the reaction [Copper results in increased oxidation of Ascorbic Acid]; APP protein modified form inhibits the reaction [[Copper co-treated with Ascorbic Acid] results in increased oxidation of phosphatidylcholine hydroperoxide]; Copper promotes the reaction [APP protein modified form results in increased oxidation of Ascorbic Acid]; Deferoxamine inhibits the reaction [[[[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of phosphatidylcholine hydroperoxide] which results in increased chemical synthesis of 4-hydroxy-2-nonenal]; Edetic Acid inhibits the reaction [[[[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of phosphatidylcholine hydroperoxide] which results in increased chemical synthesis of 4-hydroxy-2-nonenal]; Edetic Acid inhibits the reaction [[[[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of Phosphatidylcholines] which results in increased chemical synthesis of phosphatidylcholine hydroperoxide]; Penicillamine inhibits the reaction [[[[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of Phosphatidylcholines] which results in increased chemical synthesis of phosphatidylcholine hydroperoxide]; Trientine inhibits the reaction [[[[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of phosphatidylcholine hydroperoxide] which results in increased chemical synthesis of 4-hydroxy-2-nonenal]; Trientine inhibits the reaction [[[[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of Phosphatidylcholines] which results in increased chemical synthesis of phosphatidylcholine hydroperoxide]
CTD PMID:15030205, PMID:17964426, PMID:24276282, PMID:25654502 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in decreased expression of AQP3 mRNA CTD PMID:17639512 NCBI chr 5:57,423,735...57,429,252
Ensembl chr 5:57,423,734...57,429,245
JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha increases expression ISO Ascorbic Acid results in increased expression of ARHGDIA mRNA CTD PMID:22139585 NCBI chr10:109,754,012...109,757,506
Ensembl chr10:109,754,004...109,757,550
JBrowse link
G Arhgdib Rho GDP dissociation inhibitor beta multiple interactions
increases expression
ISO [Quercetin co-treated with Ascorbic Acid] results in increased expression of ARHGDIB mRNA
Ascorbic Acid results in increased expression of ARHGDIB protein
CTD PMID:17639512, PMID:22139585 NCBI chr 4:170,913,920...170,932,789
Ensembl chr 4:170,913,923...170,932,618
JBrowse link
G Arpc5 actin related protein 2/3 complex, subunit 5 increases expression ISO Ascorbic Acid results in increased expression of ARPC5 mRNA; Ascorbic Acid results in increased expression of ARPC5 protein CTD PMID:22139585 NCBI chr13:70,174,970...70,183,879
Ensembl chr13:70,174,936...70,183,879
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) decreases expression ISO Ascorbic Acid results in decreased expression of ASNS mRNA CTD PMID:19197388 NCBI chr 4:33,742,876...33,761,106
Ensembl chr 4:33,743,364...33,761,163
JBrowse link
G Atad2 ATPase family, AAA domain containing 2 multiple interactions ISO [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of ATAD2 mRNA CTD PMID:26424790 NCBI chr 7:97,984,754...98,027,379
Ensembl chr 7:97,984,862...98,026,052
JBrowse link
G Atad2b ATPase family, AAA domain containing 2B multiple interactions ISO [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of ATAD2B mRNA CTD PMID:26424790 NCBI chr 6:28,998,080...29,066,850
Ensembl chr 6:29,012,007...29,163,134
JBrowse link
G Atf3 activating transcription factor 3 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in increased expression of ATF3 mRNA CTD PMID:17639512 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Atm ATM serine/threonine kinase multiple interactions ISO [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of ATM mRNA
Ascorbic Acid inhibits the reaction [potassium chromate(VI) results in increased expression of ATM protein modified form]
CTD PMID:17917374, PMID:25977998 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
JBrowse link
G Atp5f1b ATP synthase F1 subunit beta increases expression ISO Ascorbic Acid results in increased expression of ATP5B protein CTD PMID:22139585 NCBI chr 7:2,504,708...2,511,748
Ensembl chr 7:2,504,695...2,511,749
JBrowse link
G Atp6v1a ATPase H+ transporting V1 subunit A increases expression ISO Ascorbic Acid results in increased expression of ATP6V1A mRNA CTD PMID:22139585 NCBI chr11:61,531,386...61,584,634
Ensembl chr11:61,531,416...61,584,634
JBrowse link
G Aurkb aurora kinase B multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in increased expression of AURKB mRNA CTD PMID:17639512 NCBI chr10:55,625,860...55,632,399
Ensembl chr10:55,626,741...55,634,991
JBrowse link
G Auts2 activator of transcription and developmental regulator AUTS2 increases expression ISO Ascorbic Acid results in increased expression of AUTS2 mRNA CTD PMID:25555879 NCBI chr12:27,155,362...28,252,752
Ensembl chr12:28,212,333...28,251,816
JBrowse link
G B2m beta-2 microglobulin increases expression EXP Ascorbic Acid results in increased expression of B2M mRNA CTD PMID:15372504 NCBI chr 3:114,087,287...114,093,311
Ensembl chr 3:114,087,287...114,093,309
JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions EXP
ISO
Ascorbic Acid inhibits the reaction [Potassium Dichromate affects the localization of BAD protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased phosphorylation of BAD protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in increased expression of BAD protein]
[juglone co-treated with Ascorbic Acid] results in increased expression of BAD protein
CTD PMID:21262251, PMID:29992683 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions ISO [arsenic trioxide co-treated with Ascorbic Acid co-treated with Disulfiram] results in decreased expression of BAK1 protein CTD PMID:24126434 NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO
EXP
[Arsenic Trioxide co-treated with Ascorbic Acid co-treated with Disulfiram] results in increased expression of BAX protein; [juglone co-treated with Ascorbic Acid] results in increased expression of BAX protein; Ascorbic Acid inhibits the reaction [deoxynivalenol results in increased expression of BAX protein]; Ascorbic Acid inhibits the reaction [Silicon Dioxide results in increased expression of BAX mRNA]; Ascorbic Acid inhibits the reaction [Silicon Dioxide results in increased expression of BAX protein]
Ascorbic Acid inhibits the reaction [glycidamide results in increased expression of BAX mRNA]
Ascorbic Acid inhibits the reaction [Humic Substances results in increased expression of BAX protein]; Ascorbic Acid inhibits the reaction [lead acetate results in increased expression of BAX protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate affects the localization of BAX protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in increased expression of BAX protein]; Ascorbic Acid inhibits the reaction [Streptozocin results in increased expression of BAX protein]
CTD PMID:17166419, PMID:17959157, PMID:18683188, PMID:18758938, PMID:21262251, PMID:22245848, PMID:24126434, PMID:29992683, PMID:32632975 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bbc3 Bcl-2 binding component 3 multiple interactions ISO [Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of BBC3 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of BBC3 protein] CTD PMID:20530418 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Bche butyrylcholinesterase multiple interactions ISO [Resveratrol co-treated with Ascorbic Acid co-treated with Thioctic Acid co-treated with Vitamin E] results in increased activity of BCHE protein; Hexachlorocyclohexane inhibits the reaction [[Resveratrol co-treated with Ascorbic Acid co-treated with Thioctic Acid co-treated with Vitamin E] results in increased activity of BCHE protein] CTD PMID:20663516 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions
increases abundance
ISO
EXP
Ascorbic Acid results in decreased expression of BCL2 mRNA
Ascorbic Acid inhibits the reaction [glycidamide results in decreased expression of BCL2 mRNA]
[arsenic trioxide co-treated with Ascorbic Acid co-treated with Disulfiram] results in decreased expression of BCL2 protein; [Ascorbic Acid co-treated with Quartz] results in increased expression of BCL2 mRNA; Ascorbic Acid inhibits the reaction [deoxynivalenol results in decreased expression of BCL2 protein]; Ascorbic Acid inhibits the reaction [Silicon Dioxide results in decreased expression of BCL2 mRNA]; Ascorbic Acid inhibits the reaction [Silicon Dioxide results in decreased expression of BCL2 protein]
Ascorbic Acid inhibits the reaction [Humic Substances results in decreased expression of BCL2 protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of BCL2 protein]; Ascorbic Acid inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Ascorbic Acid promotes the reaction [lead acetate results in increased expression of BCL2 protein]
BCL2 protein results in increased abundance of Ascorbic Acid
CTD PMID:15449323, PMID:17166419, PMID:17959157, PMID:18683188, PMID:18758938, PMID:21262251, PMID:21919647, PMID:22245848, PMID:24126434, PMID:27381660, PMID:32632975 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions EXP Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of BCL2L1 protein]; Ascorbic Acid inhibits the reaction [Streptozocin results in decreased expression of BCL2L1 protein] CTD PMID:18758938, PMID:21262251 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bcl2l14 BCL2 like 14 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in decreased expression of BCL2L14 mRNA CTD PMID:17639512 NCBI chr 4:168,139,964...168,183,726
Ensembl chr 4:168,142,271...168,183,096
JBrowse link
G Bcl2l2 Bcl2-like 2 multiple interactions ISO [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of BCL2L2 mRNA CTD PMID:17917374 NCBI chr15:33,543,774...33,549,165
Ensembl chr15:33,544,312...33,549,164
JBrowse link
G Bco1 beta-carotene oxygenase 1 multiple interactions EXP Ascorbic Acid inhibits the reaction [Oxidants inhibits the reaction [BCO1 protein results in increased oxidation of beta Carotene]] CTD PMID:9526112 NCBI chr19:49,637,059...49,673,577
Ensembl chr19:49,637,016...49,673,808
JBrowse link
G Bdnf brain-derived neurotrophic factor increases expression ISO Ascorbic Acid results in increased expression of BDNF mRNA CTD PMID:15305145 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Bglap bone gamma-carboxyglutamate protein multiple interactions
affects binding
ISO
EXP
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA; [Ascorbic Acid co-treated with Copper] affects the cleavage of BGLAP3 protein; [Ascorbic Acid co-treated with Dexamethasone] results in increased expression of BGLAP mRNA; [Cholecalciferol co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of BGLAP protein; bexarotene inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; rosiglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; tributyltin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of BGLAP mRNA]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of BGLAP protein]; [[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of BGLAP mRNA; [[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of BGLAP protein; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA; [Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of BGLAP mRNA; [Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of BGLAP protein; Allethrins inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; d,d-T80-prallethrin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of BGLAP mRNA]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of BGLAP protein]; Pioglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; quinoxyfen inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; Rosiglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; Tretinoin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; triphenyltin hydroxide inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]
[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of BGLAP mRNA; Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of BGLAP mRNA]; Quercetin affects the reaction [Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of BGLAP mRNA]]
BGLAP3 protein binds to Ascorbic Acid
CTD PMID:11396734, PMID:12510807, PMID:17692823, PMID:25932594, PMID:26492236, PMID:27028516, PMID:31935364, PMID:32473317 NCBI chr 2:187,741,770...187,748,445
Ensembl chr 2:187,741,770...187,742,747
JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions ISO [juglone co-treated with Ascorbic Acid] affects the expression of BID protein CTD PMID:29992683 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in increased expression of BIRC3 mRNA CTD PMID:17639512 NCBI chr 8:6,048,590...6,076,828
Ensembl chr 8:6,048,969...6,076,598
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO Ascorbic Acid results in decreased expression of BIRC5 mRNA CTD PMID:21919647 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Bmp1 bone morphogenetic protein 1 multiple interactions EXP [Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP1 mRNA CTD PMID:15994055 NCBI chr15:52,166,401...52,210,786
Ensembl chr15:52,166,401...52,210,746
JBrowse link
G Bmp2 bone morphogenetic protein 2 multiple interactions EXP
ISO
[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 protein; Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 protein]; ginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 protein]]; NOG protein inhibits the reaction [ginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 protein]]]
[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 mRNA; [Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 protein; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 mRNA]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 protein]
CTD PMID:15994055, PMID:26492236, PMID:27387537 NCBI chr 3:126,335,963...126,346,771
Ensembl chr 3:126,335,863...126,346,318
JBrowse link
G Bmp3 bone morphogenetic protein 3 multiple interactions EXP [Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP3 mRNA CTD PMID:15994055 NCBI chr14:12,362,912...12,387,572
Ensembl chr14:12,359,363...12,387,102
JBrowse link
G Bmp7 bone morphogenetic protein 7 multiple interactions EXP [Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP7 mRNA CTD PMID:15994055 NCBI chr 3:170,879,972...170,955,820
Ensembl chr 3:170,879,973...170,955,399
JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A multiple interactions EXP [Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMPR1A protein; Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMPR1A protein]; ginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMPR1A protein]]; NOG protein inhibits the reaction [ginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMPR1A protein]]] CTD PMID:27387537 NCBI chr16:10,758,278...10,852,170
Ensembl chr16:10,758,527...10,802,512
JBrowse link
G Bmpr1b bone morphogenetic protein receptor type 1B increases expression ISO Ascorbic Acid results in increased expression of BMPR1B mRNA CTD PMID:15305145 NCBI chr 2:247,392,195...247,662,026
Ensembl chr 2:247,403,920...247,446,882
JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in increased expression of BUB1 mRNA CTD PMID:17639512 NCBI chr 3:120,373,604...120,404,910
Ensembl chr 3:120,373,604...120,404,910
JBrowse link
G C3 complement C3 increases expression EXP Ascorbic Acid results in increased expression of C3 mRNA CTD PMID:15372504 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G C5 complement C5 multiple interactions ISO Ascorbic Acid inhibits the reaction [Asbestos, Crocidolite results in increased cleavage of C5 protein]; Ascorbic Acid inhibits the reaction [Asbestos, Serpentine results in increased cleavage of C5 protein] CTD PMID:10777245 NCBI chr 3:14,049,993...14,113,931
NCBI chr 3:14,206,466...14,229,141
Ensembl chr 3:14,049,995...14,229,080
JBrowse link
G Ca9 carbonic anhydrase 9 multiple interactions ISO Ascorbic Acid inhibits the reaction [nickel sulfate results in increased expression of CA9 protein] CTD PMID:16288478 NCBI chr 5:59,008,277...59,015,535
Ensembl chr 5:59,008,933...59,015,528
JBrowse link
G Calb2 calbindin 2 multiple interactions EXP Ascorbic Acid inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of CALB2 protein] CTD PMID:31708536 NCBI chr19:41,482,743...41,509,617
Ensembl chr19:41,482,728...41,509,658
JBrowse link
G Car2 carbonic anhydrase 2 increases expression ISO Ascorbic Acid results in increased expression of CAR2 mRNA CTD PMID:15730627 NCBI chr 2:88,097,740...88,112,868
Ensembl chr 2:88,097,720...88,113,029
JBrowse link
G Casp2 caspase 2 multiple interactions EXP Ascorbic Acid inhibits the reaction [Norepinephrine results in increased activity of CASP2 protein] CTD PMID:15158148 NCBI chr 4:71,652,358...71,670,228
Ensembl chr 4:71,652,354...71,670,239
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
decreases activity
ISO
EXP
[Ascorbic Acid co-treated with Eosine I Bluish] results in increased activity of CASP3 protein; [Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of CASP3 protein; [Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CASP3 mRNA; [Hyaluronic Acid co-treated with Chondroitin Sulfates] inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of CASP3 protein]; [Hyaluronic Acid co-treated with Chondroitin Sulfates] inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CASP3 mRNA]; [juglone co-treated with Ascorbic Acid] results in decreased expression of CASP3 protein; Ascorbic Acid inhibits the reaction [deoxynivalenol results in increased expression of CASP3 protein]; Ascorbic Acid inhibits the reaction [Fenretinide results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [Oleanolic Acid results in increased cleavage of CASP3 protein]; Ascorbic Acid inhibits the reaction [Reactive Oxygen Species results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [Silicon Dioxide results in decreased expression of CASP3 mRNA]; Ascorbic Acid inhibits the reaction [Silicon Dioxide results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [TNFSF10 protein results in increased activity of CASP3 protein]; Ascorbic Acid promotes the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; Ascorbic Acid promotes the reaction [Arsenic Trioxide results in increased cleavage of and results in increased activity of CASP3 protein]; Ascorbic Acid promotes the reaction [chromium hexavalent ion results in increased cleavage of CASP3 protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with Eosine I Bluish] results in increased activity of CASP3 protein]
Ascorbic Acid inhibits the reaction [glycidamide results in increased expression of CASP3 mRNA]
Ascorbic Acid results in increased expression of CASP3 mRNA
[Vitamin E co-treated with Ascorbic Acid] inhibits the reaction [Dichlorvos results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]; Ascorbic Acid inhibits the reaction [Arsenic results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [Norepinephrine results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in increased cleavage of CASP3 protein]; Ascorbic Acid inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]
Ascorbic Acid results in decreased activity of CASP3 protein
CTD PMID:12750841, PMID:15158148, PMID:16124896, PMID:16407847, PMID:16867262, PMID:16973328, PMID:17166419, PMID:17301063, PMID:17618090, PMID:17879260, PMID:18758938, PMID:20356860, PMID:21262251, PMID:21873648, PMID:22245848, PMID:22678527, PMID:23711929, PMID:24295472, PMID:24488945, PMID:29992683, PMID:30597948, PMID:32632975 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp4 caspase 4 multiple interactions EXP Ascorbic Acid inhibits the reaction [[kojic acid co-treated with Diethylnitrosamine] results in increased expression of CASP4 mRNA] CTD PMID:18544905 NCBI chr 8:2,616,391...2,651,682
Ensembl chr 8:2,635,851...2,651,652
JBrowse link
G Casp6 caspase 6 multiple interactions EXP Ascorbic Acid inhibits the reaction [Norepinephrine results in increased activity of CASP6 protein] CTD PMID:15158148 NCBI chr 2:235,341,326...235,353,715
Ensembl chr 2:235,341,365...235,353,967
Ensembl chr 2:235,341,365...235,353,967
JBrowse link
G Casp7 caspase 7 multiple interactions ISO [Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of CASP7 protein; [Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CASP7 mRNA; [Hyaluronic Acid co-treated with Chondroitin Sulfates] inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of CASP7 protein]; [Hyaluronic Acid co-treated with Chondroitin Sulfates] inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CASP7 mRNA]; Ascorbic Acid promotes the reaction [chromium hexavalent ion results in increased cleavage of CASP7 protein] CTD PMID:17301063, PMID:17879260 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp8 caspase 8 multiple interactions
increases expression
EXP
ISO
[Ascorbic Acid co-treated with INS1 protein] results in increased expression of CASP8 mRNA; [Ascorbic Acid co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CASP8 mRNA
Ascorbic Acid results in increased expression of CASP8 mRNA
Ascorbic Acid inhibits the reaction [TNFSF10 protein results in increased activity of CASP8 protein]
CTD PMID:18544905, PMID:20400526, PMID:23711929, PMID:30597948 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 multiple interactions EXP
ISO
[Vitamin E co-treated with Ascorbic Acid] inhibits the reaction [Dichlorvos results in increased activity of CASP9 protein]; Ascorbic Acid inhibits the reaction [Norepinephrine results in increased activity of CASP9 protein]
Ascorbic Acid inhibits the reaction [TNFSF10 protein results in increased activity of CASP9 protein]
CTD PMID:15158148, PMID:16973328, PMID:23711929 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cast calpastatin increases expression EXP Ascorbic Acid results in increased expression of CAST mRNA CTD PMID:15372504 NCBI chr 2:1,452,111...1,561,669
Ensembl chr 2:1,452,116...1,561,464
JBrowse link
G Cat catalase affects expression
increases activity
increases expression
decreases activity
multiple interactions
decreases response to substance
ISO
EXP
Ascorbic Acid affects the expression of CAT protein
Ascorbic Acid results in increased activity of CAT protein
Ascorbic Acid results in increased expression of CAT mRNA
Ascorbic Acid results in decreased activity of CAT protein
[Ascorbic Acid co-treated with beta Carotene co-treated with alpha-Tocopherol co-treated with Sodium Selenite] inhibits the reaction [Galactosamine results in increased activity of CAT protein]; [Ascorbic Acid co-treated with Lead] results in increased expression of CAT protein; [Ascorbic Acid co-treated with sodium arsenite] results in increased activity of CAT protein; [Zinc co-treated with Vitamin E co-treated with Ascorbic Acid co-treated with sodium arsenite] results in increased activity of CAT protein; Ascorbic Acid inhibits the reaction [Arsenic results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [bisphenol A results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [Cadmium results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [Cisplatin results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [Cyclosporine results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [Food Additives affects the activity of CAT protein]; Ascorbic Acid inhibits the reaction [Indomethacin results in increased activity of CAT protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of CAT mRNA]; Ascorbic Acid inhibits the reaction [sodium arsenite results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [sodium arsenite results in decreased expression of CAT protein]; Ascorbic Acid inhibits the reaction [sodium arsenite results in increased activity of CAT protein]
[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Air Pollutants, Occupational affects the expression of CAT protein]; [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Malathion results in increased activity of CAT protein]; [Ascorbic Acid co-treated with Vitamin E] results in increased expression of CAT mRNA; [juglone co-treated with Ascorbic Acid] results in decreased activity of CAT protein; Ascorbic Acid inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of CAT mRNA]; Ascorbic Acid inhibits the reaction [Dimethoate results in increased activity of CAT protein]; Ascorbic Acid inhibits the reaction [Malathion results in increased activity of CAT protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with Eosine I Bluish] results in increased activity of CASP3 protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with Eosine I Bluish] results in increased phosphorylation of MAPK8 protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with Eosine I Bluish] results in increased phosphorylation of MAPK9 protein]; CAT protein inhibits the reaction [Copper promotes the reaction [Ascorbic Acid results in decreased activity of PON1 protein]]; CAT protein results in decreased susceptibility to [Arsenic Trioxide co-treated with Ascorbic Acid]; CAT results in decreased susceptibility to [Vitamin K 3 co-treated with Ascorbic Acid]
Ascorbic Acid results in increased expression of CAT protein
[Ascorbic Acid co-treated with CAT protein] inhibits the reaction [Zinc deficiency results in increased expression of IREB2 protein]; [Ascorbic Acid co-treated with CAT protein] inhibits the reaction [Zinc deficiency results in increased expression of TFRC protein]; Ascorbic Acid inhibits the reaction [Arsenic Trioxide results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [Cadmium Chloride results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [fipronil results in decreased activity of CAT protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of [NFKB1 protein binds to RELA protein]]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased degradation of Hyaluronic Acid]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CD44 mRNA]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CD44 protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of IL1B mRNA]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of IL1B protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of MMP13 mRNA]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of MMP13 protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of NOS2 mRNA]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of NOS2 protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TLR2 mRNA]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TLR2 protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TLR4 mRNA]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TLR4 protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TNF mRNA]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TNF protein]; CAT protein inhibits the reaction [Ascorbic Acid promotes the reaction [Quartz results in increased secretion of TNF protein]]
CAT protein results in decreased susceptibility to Ascorbic Acid
CTD PMID:10772068, PMID:12540038, PMID:12767684, PMID:14698046, PMID:15104111, PMID:16248992, PMID:16298753, PMID:16758767, PMID:17512118, PMID:17822687, PMID:18073202, PMID:18096215, PMID:18548748, PMID:18655177, PMID:18715643, PMID:18726076, PMID:19298665, PMID:19391111, PMID:19429265, PMID:20028703, PMID:20077558, PMID:20122981, PMID:20171736, PMID:20535553, PMID:20876158, PMID:21310208, PMID:21689642, PMID:22008531, PMID:22056337, PMID:22207723, PMID:23194016, PMID:23470461, PMID:23619517, PMID:23692848, PMID:24295472, PMID:24488945, PMID:25721553, PMID:29572072, PMID:29992683, PMID:31005848, PMID:31022331, PMID:31576639, PMID:31610155 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cbs cystathionine beta synthase decreases expression ISO Ascorbic Acid results in decreased expression of CBS mRNA CTD PMID:19197388 NCBI chr20:10,361,987...10,386,663
Ensembl chr20:10,361,988...10,386,751
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 affects expression
decreases expression
ISO Ascorbic Acid affects the expression of CCL2 mRNA; Ascorbic Acid deficiency affects the expression of CCL2 mRNA
Ascorbic Acid results in decreased expression of CCL2 mRNA
CTD PMID:19932582, PMID:21796779 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl21 C-C motif chemokine ligand 21 multiple interactions ISO [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CCL21A mRNA CTD PMID:17917374 NCBI chr 5:58,197,678...58,198,782
Ensembl chr 5:58,197,680...58,198,782
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions ISO [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CCL3 mRNA CTD PMID:17917374 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ccna1 cyclin A1 multiple interactions EXP Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of CCNA1 protein] CTD PMID:21621607 NCBI chr 2:144,456,689...144,503,570
Ensembl chr 2:144,458,153...144,467,912
JBrowse link
G Ccnb1 cyclin B1 multiple interactions EXP Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of CCNB1 protein] CTD PMID:21621607 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Ccnc cyclin C multiple interactions ISO [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CCNC mRNA CTD PMID:17917374 NCBI chr 5:35,865,598...35,883,732
Ensembl chr 5:35,865,605...35,883,706
JBrowse link
G Ccnd1 cyclin D1 multiple interactions
decreases expression
ISO
EXP
[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CCND1 mRNA; Ascorbic Acid inhibits the reaction [phenylhydrazine results in decreased expression of CCND1 mRNA]
Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of CCND1 protein]
Ascorbic Acid results in decreased expression of CCND1 mRNA
CTD PMID:17917374, PMID:21621607, PMID:21919647, PMID:30140404 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccnd2 cyclin D2 multiple interactions ISO
EXP
[Quercetin co-treated with Ascorbic Acid] results in increased expression of CCND2 mRNA
Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of CCND2 protein]
CTD PMID:17639512, PMID:21621607 NCBI chr 4:159,674,885...159,697,207
Ensembl chr 4:159,674,885...159,697,207
JBrowse link
G Ccnd3 cyclin D3 multiple interactions EXP
ISO
Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of CCND3 protein]
Ascorbic Acid promotes the reaction [juglone results in decreased expression of CCND3 protein]
CTD PMID:21621607, PMID:29992683 NCBI chr 9:15,404,816...15,410,905
Ensembl chr 9:15,404,822...15,410,943
JBrowse link
G Ccne2 cyclin E2 multiple interactions EXP Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of CCNE2 protein] CTD PMID:21621607 NCBI chr 5:24,434,077...24,446,406
Ensembl chr 5:24,434,872...24,446,406
JBrowse link
G Ccng1 cyclin G1 multiple interactions ISO
EXP
[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CCNG1 mRNA
[Ascorbic Acid co-treated with kojic acid co-treated with Diethylnitrosamine] results in increased expression of CCNG1 mRNA
CTD PMID:17917374, PMID:18544905 NCBI chr10:25,903,925...25,910,298
Ensembl chr10:25,903,911...25,910,325
JBrowse link
G Cd24 CD24 molecule multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in increased expression of CD24 mRNA CTD PMID:17639512 NCBI chr20:48,335,540...48,340,847
Ensembl chr20:48,335,540...48,340,846
JBrowse link
G Cd34 CD34 molecule multiple interactions ISO [Tretinoin co-treated with Ascorbic Acid] results in decreased expression of CD34 mRNA CTD PMID:16443354 NCBI chr13:113,691,842...113,711,259
Ensembl chr13:113,691,932...113,711,647
JBrowse link
G Cd40 CD40 molecule multiple interactions ISO [Tretinoin co-treated with Ascorbic Acid] results in decreased expression of CD40 mRNA CTD PMID:16443354 NCBI chr 3:161,519,789...161,534,943
Ensembl chr 3:161,519,743...161,534,704
JBrowse link
G Cd44 CD44 molecule (Indian blood group) multiple interactions ISO [Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CD44 mRNA; [Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CD44 protein; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CD44 mRNA]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CD44 protein]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CD44 mRNA]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CD44 protein] CTD PMID:23692848 NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658
JBrowse link
G Cd48 Cd48 molecule increases expression EXP Ascorbic Acid results in increased expression of CD48 mRNA CTD PMID:15372504 NCBI chr13:90,116,601...90,140,371
Ensembl chr13:90,116,843...90,140,371
JBrowse link
G Cd69 Cd69 molecule decreases expression ISO Ascorbic Acid deficiency results in decreased expression of CD69 protein CTD PMID:22306178 NCBI chr 4:163,041,147...163,049,065
Ensembl chr 4:163,041,141...163,049,084
JBrowse link
G Cd82 Cd82 molecule increases expression EXP Ascorbic Acid results in increased expression of CD82 mRNA CTD PMID:15372504 NCBI chr 3:82,324,344...82,368,846
Ensembl chr 3:82,324,354...82,368,357
JBrowse link
G Cdc6 cell division cycle 6 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in increased expression of CDC6 mRNA CTD PMID:17639512 NCBI chr10:86,819,477...86,833,301
Ensembl chr10:86,819,472...86,833,402
JBrowse link
G Cdh13 cadherin 13 increases expression ISO Ascorbic Acid results in increased expression of CDH13 mRNA CTD PMID:15305145 NCBI chr19:50,848,793...51,971,618
Ensembl chr19:50,848,736...51,972,103
JBrowse link
G Cdh2 cadherin 2 multiple interactions EXP [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [mono-(2-ethylhexyl)phthalate affects the localization of CDH2 protein] CTD PMID:29940330 NCBI chr18:8,146,971...8,366,037
Ensembl chr18:8,146,971...8,360,684
JBrowse link
G Cdh22 cadherin 22 increases expression EXP Ascorbic Acid results in increased expression of CDH22 mRNA CTD PMID:15372504 NCBI chr 3:161,574,993...161,971,102
Ensembl chr 3:161,575,631...161,917,285
JBrowse link
G Cdk1 cyclin-dependent kinase 1 multiple interactions EXP Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of CDK1 protein] CTD PMID:21621607 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions EXP Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of CDK2 protein] CTD PMID:21621607 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Cdk4 cyclin-dependent kinase 4 multiple interactions EXP
ISO
Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of CDK4 protein]
[juglone co-treated with Ascorbic Acid] results in decreased expression of CDK4 protein
CTD PMID:21621607, PMID:29992683 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
JBrowse link
G Cdk6 cyclin-dependent kinase 6 multiple interactions EXP Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of CDK6 protein] CTD PMID:21621607 NCBI chr 4:27,781,728...27,969,653
Ensembl chr 4:27,785,647...27,966,398
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression
ISO
EXP
[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CDKN1A mRNA
Ascorbic Acid results in increased expression of CDKN1A mRNA
[INS1 protein co-treated with Ascorbic Acid] results in increased expression of CDKN1A mRNA; Ascorbic Acid inhibits the reaction [potassium bromate results in increased expression of CDKN1A protein]
[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CDKN1A mRNA; Ascorbic Acid inhibits the reaction [potassium bromate results in increased expression of CDKN1A protein]; nutlin 3 inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CDKN1A mRNA]
CTD PMID:17917374, PMID:20067818, PMID:20400526, PMID:20530418 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions EXP [Ascorbic Acid co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CDKN1B mRNA CTD PMID:18544905 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A multiple interactions EXP Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in increased expression of CDKN2A protein] CTD PMID:21621607 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha multiple interactions ISO [Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of CEBPA protein
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of CEBPA mRNA
CTD PMID:14505802, PMID:25932594 NCBI chr 1:91,363,492...91,366,164
Ensembl chr 1:91,363,492...91,366,164
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression EXP Ascorbic Acid results in increased expression of CEBPB mRNA CTD PMID:15372504 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Cfb complement factor B multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in decreased expression of CFB mRNA CTD PMID:17639512 NCBI chr20:4,536,206...4,542,073
Ensembl chr20:4,536,203...4,561,066
Ensembl chr20:4,536,203...4,561,066
JBrowse link
G Cftr CF transmembrane conductance regulator multiple interactions
increases activity
ISO [Bicarbonates co-treated with Glutathione co-treated with Ascorbic Acid] results in increased activity of CFTR protein; Ascorbic Acid promotes the reaction [CFTR protein results in increased secretion of Chlorides]
Ascorbic Acid results in increased activity of CFTR protein
CTD PMID:14993613, PMID:32374624 NCBI chr 4:42,693,263...42,860,679
Ensembl chr 4:42,692,836...42,860,676
JBrowse link
G Chaf1b chromatin assembly factor 1 subunit B multiple interactions ISO [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of CHAF1B mRNA CTD PMID:26424790 NCBI chr11:34,101,248...34,121,371
Ensembl chr11:34,101,197...34,121,378
JBrowse link
G Chat choline O-acetyltransferase multiple interactions EXP [Ascorbic Acid co-treated with alpha-Tocopherol co-treated with Acetylcysteine] results in increased expression of CHAT protein; Tobacco Smoke Pollution inhibits the reaction [[Ascorbic Acid co-treated with alpha-Tocopherol co-treated with Acetylcysteine] results in increased expression of CHAT protein] CTD PMID:25891525 NCBI chr16:8,576,858...8,686,131
Ensembl chr16:8,577,840...8,686,131
JBrowse link
G Chek2 checkpoint kinase 2 multiple interactions EXP
ISO
Ascorbic Acid inhibits the reaction [[kojic acid co-treated with Diethylnitrosamine] results in increased expression of CHEK2 mRNA]
Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in increased phosphorylation of CHEK2 protein]; Ascorbic Acid inhibits the reaction [potassium chromate(VI) results in increased expression of CHEK2 protein modified form]; Ascorbic Acid inhibits the reaction [potassium chromate(VI) results in increased phosphorylation of CHEK2 protein]
CTD PMID:18544905, PMID:25977998, PMID:31388677 NCBI chr12:51,845,574...51,878,098
Ensembl chr12:51,845,796...51,877,624
JBrowse link
G Cit citron rho-interacting serine/threonine kinase multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in increased expression of CIT mRNA CTD PMID:17639512 NCBI chr12:46,334,669...46,494,152
Ensembl chr12:46,334,665...46,494,174
JBrowse link
G Cited1 Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 multiple interactions ISO [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of CITED1 mRNA; cadmium sulfate inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of CITED1 mRNA] CTD PMID:28189605 NCBI chr  X:72,128,996...72,133,692
Ensembl chr  X:72,128,994...72,133,692
JBrowse link
G Clu clusterin increases expression EXP Ascorbic Acid results in increased expression of CLU mRNA CTD PMID:15372504 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857
JBrowse link
G Cmip c-Maf-inducing protein increases expression
multiple interactions
ISO Ascorbic Acid results in increased expression of CMIP mRNA
[arsenic trioxide co-treated with Ascorbic Acid] results in increased expression of CMIP mRNA
CTD PMID:25555879 NCBI chr19:49,792,273...50,000,535
Ensembl chr19:49,792,273...50,000,535
JBrowse link
G Cnn1 calponin 1 multiple interactions
increases expression
ISO
EXP
[Ascorbic Acid co-treated with TGFB1 protein] results in increased expression of CNN1 mRNA; [Ascorbic Acid co-treated with TGFB1 protein] results in increased expression of CNN1 protein
Ascorbic Acid results in increased expression of CNN1 protein
CTD PMID:14639096, PMID:18607632 NCBI chr 8:23,113,083...23,121,748
Ensembl chr 8:23,113,048...23,121,761
JBrowse link
G Cntf ciliary neurotrophic factor multiple interactions ISO Ascorbic Acid inhibits the reaction [Mercuric Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT1 protein]]; Ascorbic Acid inhibits the reaction [Mercuric Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT3 protein]] CTD PMID:16896058 NCBI chr 1:229,599,009...229,601,032
Ensembl chr 1:229,599,009...229,601,032
JBrowse link
G Cntnap1 contactin associated protein 1 multiple interactions ISO [arsenic trioxide co-treated with Ascorbic Acid] results in increased expression of CNTNAP1 mRNA CTD PMID:25555879 NCBI chr10:89,087,904...89,103,615
Ensembl chr10:89,089,646...89,103,614
JBrowse link
G Col10a1 collagen type X alpha 1 chain increases expression
multiple interactions
ISO Ascorbic Acid results in increased expression of COL10A1 mRNA
U 0126 inhibits the reaction [Ascorbic Acid results in increased expression of COL10A1 mRNA]
CTD PMID:20530736 NCBI chr20:41,180,295...41,190,664
Ensembl chr20:41,184,287...41,189,633
JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression
multiple interactions
ISO Ascorbic Acid results in increased expression of COL1A1 mRNA
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of COL1A1 mRNA]; [[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of COL1A1 mRNA
CTD PMID:12510807, PMID:14566779, PMID:28105418, PMID:31935364 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Col1a2 collagen type I alpha 2 chain increases expression
multiple interactions
EXP
ISO
Ascorbic Acid results in increased expression of COL1A2 mRNA
[arsenic trioxide co-treated with Ascorbic Acid] results in increased expression of COL1A2 mRNA
CTD PMID:15372504, PMID:25555879 NCBI chr 4:31,534,225...31,569,152
Ensembl chr 4:31,534,225...31,569,151
JBrowse link
G Col2a1 collagen type II alpha 1 chain increases expression
multiple interactions
EXP
ISO
Ascorbic Acid results in increased expression of COL2A1 mRNA
[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of COL2A1 mRNA; IL1B protein inhibits the reaction [[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of COL2A1 mRNA]; resveratrol inhibits the reaction [IL1B protein inhibits the reaction [[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of COL2A1 mRNA]]
CTD PMID:15372504, PMID:26526931 NCBI chr 7:139,454,945...139,484,403
Ensembl chr 7:139,455,242...139,483,997
JBrowse link
G Cr2 complement C3d receptor 2 multiple interactions ISO [Tretinoin co-treated with Ascorbic Acid] results in decreased expression of CR2 mRNA CTD PMID:16443354 NCBI chr13:113,890,274...113,927,824
Ensembl chr13:113,890,272...113,927,877
JBrowse link
G Crip2 cysteine-rich protein 2 increases expression EXP Ascorbic Acid results in increased expression of CRIP2 mRNA CTD PMID:15372504 NCBI chr 6:137,953,545...137,958,491
Ensembl chr 6:137,953,545...137,958,490
JBrowse link
G Crp C-reactive protein multiple interactions ISO [Vitamin E co-treated with Ascorbic Acid co-treated with Folic Acid co-treated with Riboflavin co-treated with Vitamin B 6 co-treated with Vitamin B 12] results in decreased expression of CRP protein; [Vitamin E co-treated with Ascorbic Acid] results in decreased expression of CRP protein CTD PMID:16517955 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Cryab crystallin, alpha B increases expression EXP Ascorbic Acid results in increased expression of CRYAB mRNA CTD PMID:15372504 NCBI chr 8:55,178,543...55,182,546
Ensembl chr 8:55,178,289...55,182,545
JBrowse link
G Cs citrate synthase multiple interactions ISO Ascorbic Acid inhibits the reaction [FMR1 5' UTR mutant form results in decreased activity of CS protein] CTD PMID:27385396 NCBI chr 7:2,752,680...2,778,963
Ensembl chr 7:2,752,680...2,778,963
JBrowse link
G Cspg5 chondroitin sulfate proteoglycan 5 increases expression ISO Ascorbic Acid results in increased expression of CSPG5 mRNA CTD PMID:15305145 NCBI chr 8:118,333,695...118,348,040
Ensembl chr 8:118,333,706...118,347,582
JBrowse link
G Csrp1 cysteine and glycine-rich protein 1 increases expression EXP Ascorbic Acid results in increased expression of CSRP1 mRNA CTD PMID:15372504 NCBI chr13:52,553,843...52,575,054
Ensembl chr13:52,553,775...52,575,051
JBrowse link
G Cst6 cystatin E/M increases expression EXP Ascorbic Acid results in increased expression of CST6 mRNA CTD PMID:15372504 NCBI chr 1:220,727,292...220,729,000
Ensembl chr 1:220,727,292...220,729,000
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions EXP [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in increased expression of and affects the localization of CTNNB1 protein]; [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [mono-(2-ethylhexyl)phthalate affects the localization of CTNNB1 protein] CTD PMID:29940330 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Ctps2 CTP synthase 2 multiple interactions ISO [arsenic trioxide co-treated with Ascorbic Acid] results in decreased expression of CTPS2 mRNA CTD PMID:25555879 NCBI chr  X:33,383,087...33,522,852
Ensembl chr  X:33,383,087...33,522,836
JBrowse link
G Ctsd cathepsin D multiple interactions EXP [ferulic acid co-treated with Ascorbic Acid] inhibits the reaction [Isoproterenol results in increased activity of CTSD protein] CTD PMID:17045618 NCBI chr 1:215,541,570...215,553,446
Ensembl chr 1:215,541,542...215,553,451
JBrowse link
G Ctsk cathepsin K increases expression ISO Ascorbic Acid results in increased expression of CTSK mRNA CTD PMID:15730627 NCBI chr 2:196,655,469...196,666,447
Ensembl chr 2:196,655,469...196,666,446
JBrowse link
G Ctso cathepsin O multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in decreased expression of CTSO mRNA CTD PMID:17639512 NCBI chr 2:180,857,178...180,881,677 JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 increases expression EXP Ascorbic Acid deficiency results in increased expression of CXCL1 mRNA; Ascorbic Acid deficiency results in increased expression of CXCL1 protein CTD PMID:16637227 NCBI chr14:18,743,678...18,745,457
Ensembl chr14:18,743,685...18,745,457
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 decreases expression
increases expression
ISO Ascorbic Acid results in decreased expression of CXCL10 mRNA
Ascorbic Acid deficiency results in increased expression of CXCL10 mRNA
CTD PMID:19932582 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 decreases expression
increases expression
ISO Ascorbic Acid results in decreased expression of CXCL6 mRNA
Ascorbic Acid deficiency results in increased expression of CXCL6 mRNA
CTD PMID:19932582 NCBI chr14:18,860,201...18,920,839
Ensembl chr14:18,860,264...18,862,407
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 multiple interactions ISO [Tretinoin co-treated with Ascorbic Acid] results in increased expression of CXCL9 mRNA CTD PMID:16443354 NCBI chr14:17,228,832...17,233,743
Ensembl chr14:17,228,856...17,234,712
JBrowse link
G Cxcr5 C-X-C motif chemokine receptor 5 multiple interactions ISO [Tretinoin co-treated with Ascorbic Acid] results in increased expression of CXCR5 mRNA CTD PMID:16443354 NCBI chr 8:48,835,688...48,852,032
Ensembl chr 8:48,836,957...48,850,671
JBrowse link
G Cyba cytochrome b-245 alpha chain multiple interactions ISO Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of CYBA mRNA]; Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of CYBA protein] CTD PMID:25305479 NCBI chr19:55,249,634...55,257,824
Ensembl chr19:55,249,616...55,257,876
JBrowse link
G Cybb cytochrome b-245 beta chain increases expression ISO Ascorbic Acid results in increased expression of NOX2 protein CTD PMID:21570463 NCBI chr  X:14,578,330...14,610,049
Ensembl chr  X:14,578,264...14,612,547
JBrowse link
G Cybrd1 cytochrome b reductase 1 decreases expression
increases expression
ISO Ascorbic Acid results in decreased expression of CYBRD1 protein
Ascorbic Acid results in increased expression of CYBRD1 protein
CTD PMID:18815723 NCBI chr 3:57,718,496...57,745,749
Ensembl chr 3:57,718,364...57,746,097
JBrowse link
G Cycs cytochrome c, somatic multiple interactions ISO Ascorbic Acid inhibits the reaction [TNFSF10 protein affects the localization of CYCS protein] CTD PMID:23711929 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions
increases expression
EXP
ISO
Ascorbic Acid inhibits the reaction [Cadmium results in decreased expression of CYP11A1 mRNA]; Ascorbic Acid inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased activity of CYP11A1 protein]; Ascorbic Acid inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of CYP11A1 mRNA]
Ascorbic Acid results in increased expression of CYP11A1 mRNA
CTD PMID:15223132, PMID:16298753, PMID:17280759, PMID:17901237 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 multiple interactions
increases expression
ISO [Tretinoin co-treated with Ascorbic Acid] results in decreased expression of CYP19A1 mRNA
Ascorbic Acid results in increased expression of CYP19A1 mRNA
CTD PMID:16443354, PMID:17901237 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
decreases activity
ISO [Quercetin co-treated with Ascorbic Acid] results in increased expression of CYP1A1 mRNA; Ascorbic Acid inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; Ascorbic Acid inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Ascorbic Acid inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]
Ascorbic Acid affects the reaction [andrographolide affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]]; Ascorbic Acid affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in increased expression of CYP1A1 mRNA]; Ascorbic Acid inhibits the reaction [sodium arsenite results in increased expression of CYP1A1 mRNA]
Ascorbic Acid results in decreased activity of CYP1A1 protein
CTD PMID:16517059, PMID:17512695, PMID:17639512, PMID:19268519, PMID:21094198 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression EXP Ascorbic Acid deficiency results in increased expression of CYP1A2 mRNA; Ascorbic Acid deficiency results in increased expression of CYP1A2 protein CTD PMID:8269614 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 multiple interactions ISO [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CYP2A5 mRNA; Ascorbic Acid inhibits the reaction [Ethanol results in increased expression of and results in increased activity of CYP2A5 protein] CTD PMID:17917374, PMID:22552773 NCBI chr 1:83,653,248...83,662,118
Ensembl chr 1:83,653,234...83,766,484
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions ISO [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CYP2B10 mRNA CTD PMID:17917374 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 decreases expression EXP Ascorbic Acid deficiency results in decreased expression of CYP2B2 protein CTD PMID:8269614 NCBI chr 1:83,103,925...83,119,578
Ensembl chr 1:83,103,925...83,119,193
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions ISO [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CYP2B9 mRNA CTD PMID:17917374 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases activity
multiple interactions
ISO
EXP
Ascorbic Acid results in decreased activity of CYP2E1 protein
Ascorbic Acid inhibits the reaction [Ethylene Chlorohydrin results in increased expression of CYP2E1 mRNA]; Ascorbic Acid inhibits the reaction [Ethylene Chlorohydrin results in increased expression of CYP2E1 protein]
CTD PMID:17512695, PMID:31585129 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 multiple interactions ISO [Diethylnitrosamine co-treated with Ascorbic Acid] results in increased expression of CYP7A1 mRNA; [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CYP7A1 mRNA CTD PMID:17917374 NCBI chr 5:19,358,734...19,368,431
Ensembl chr 5:19,358,734...19,368,431
JBrowse link
G Dclk1 doublecortin-like kinase 1 increases expression ISO Ascorbic Acid results in increased expression of DCLK1 mRNA CTD PMID:15305145 NCBI chr 2:144,646,255...144,939,389
Ensembl chr 2:144,646,308...144,936,927
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions EXP [Ascorbic Acid co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of DDIT3 mRNA CTD PMID:18544905 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 decreases expression ISO Ascorbic Acid results in decreased expression of DKK1 mRNA CTD PMID:19197388 NCBI chr 1:248,952,896...248,956,579
Ensembl chr 1:248,895,738...248,898,607
JBrowse link
G Dkk2 dickkopf WNT signaling pathway inhibitor 2 multiple interactions ISO Ascorbic Acid inhibits the reaction [Benzo(a)pyrene results in decreased expression of DKK2 mRNA]; Ascorbic Acid inhibits the reaction [Benzo(a)pyrene results in increased methylation of DKK2 promoter] CTD PMID:27901495 NCBI chr 2:237,148,918...237,240,883
Ensembl chr 2:237,148,941...237,241,350
JBrowse link
G Dld dihydrolipoamide dehydrogenase multiple interactions ISO Ascorbic Acid inhibits the reaction [Cadmium Chloride results in decreased activity of and results in increased phosphorylation of DLD protein] CTD PMID:29158198 NCBI chr 6:50,597,677...50,618,694
Ensembl chr 6:50,597,677...50,618,694
JBrowse link
G Dlgap5 DLG associated protein 5 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in increased expression of DLGAP5 mRNA CTD PMID:17639512 NCBI chr15:24,167,484...24,199,417
Ensembl chr15:24,167,486...24,199,341
JBrowse link
G Dmp1 dentin matrix acidic phosphoprotein 1 multiple interactions ISO [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of DMP1 mRNA; bexarotene inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of DMP1 mRNA]; rosiglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of DMP1 mRNA]; tributyltin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of DMP1 mRNA] CTD PMID:25932594 NCBI chr14:6,889,851...6,923,961
Ensembl chr14:6,889,856...6,900,733
JBrowse link
G Dnajc10 DnaJ heat shock protein family (Hsp40) member C10 multiple interactions ISO Ascorbic Acid inhibits the reaction [Fenretinide results in increased expression of DNAJC10 mRNA] CTD PMID:17353921 NCBI chr 3:67,538,289...67,578,308
Ensembl chr 3:67,538,289...67,578,306
JBrowse link
G Dnase1 deoxyribonuclease 1 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in decreased expression of DNASE1 mRNA CTD PMID:17639512 NCBI chr10:11,757,681...11,760,672
Ensembl chr10:11,757,682...11,760,620
JBrowse link
G Dpf1 double PHD fingers 1 multiple interactions ISO [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of DPF1 mRNA CTD PMID:26424790 NCBI chr 1:87,248,448...87,258,070
Ensembl chr 1:87,248,489...87,258,070
JBrowse link
G Dpp4 dipeptidylpeptidase 4 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in decreased expression of DPP4 mRNA CTD PMID:17639512 NCBI chr 3:48,291,055...48,372,672
Ensembl chr 3:48,291,055...48,372,672
JBrowse link
G Dppa5 developmental pluripotency associated 5 decreases expression ISO Ascorbic Acid results in decreased expression of DPPA5A mRNA CTD PMID:15305145 NCBI chr 8:85,711,560...85,713,313
Ensembl chr 8:85,711,795...85,712,647
Ensembl chr 7:85,711,795...85,712,647
Ensembl chr 3:85,711,795...85,712,647
JBrowse link
G Dusp6 dual specificity phosphatase 6 decreases expression EXP Ascorbic Acid results in decreased expression of DUSP6 mRNA CTD PMID:15372504 NCBI chr 7:41,475,163...41,479,393
Ensembl chr 7:41,475,163...41,479,392
JBrowse link
G Edn1 endothelin 1 multiple interactions ISO [Tretinoin co-treated with Ascorbic Acid] results in increased expression of EDN1 mRNA CTD PMID:16443354 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Edn3 endothelin 3 multiple interactions ISO [Tretinoin co-treated with Ascorbic Acid] results in decreased expression of EDN3 mRNA CTD PMID:16443354 NCBI chr 3:172,856,730...172,879,276
Ensembl chr 3:172,856,733...172,880,450
JBrowse link
G Ednrb endothelin receptor type B increases expression ISO Ascorbic Acid results in increased expression of EDNRB mRNA CTD PMID:15305145 NCBI chr15:88,004,775...88,036,354
Ensembl chr15:88,006,977...88,036,354
JBrowse link
G Egfr epidermal growth factor receptor decreases expression ISO Ascorbic Acid results in decreased expression of EGFR mRNA CTD PMID:21919647 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 multiple interactions ISO EGLN1 mRNA affects the reaction [Ascorbic Acid results in increased expression of SP7 protein] CTD PMID:21467157 NCBI chr19:57,660,194...57,701,158
Ensembl chr19:57,662,278...57,699,113
JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in increased expression of EGLN3 mRNA CTD PMID:17639512 NCBI chr 6:75,050,329...75,075,795
Ensembl chr 6:75,050,329...75,075,795
JBrowse link
G Eif2s2 eukaryotic translation initiation factor 2 subunit beta decreases expression ISO Ascorbic Acid results in decreased expression of EIF2S2 mRNA CTD PMID:19197388 NCBI chr 3:150,391,455...150,412,179
Ensembl chr 3:150,391,460...150,412,179
JBrowse link
G Eif3a eukaryotic translation initiation factor 3, subunit A decreases expression ISO Ascorbic Acid results in decreased expression of EIF3A mRNA CTD PMID:19197388 NCBI chr 1:282,139,809...282,170,017
Ensembl chr 1:282,139,823...282,170,017
JBrowse link
G Eif3c eukaryotic translation initiation factor 3, subunit C decreases expression ISO Ascorbic Acid results in decreased expression of EIF3C mRNA CTD PMID:19197388 NCBI chr 1:197,964,406...197,982,917
Ensembl chr 1:197,964,407...197,982,601
JBrowse link
G Eif3i eukaryotic translation initiation factor 3, subunit I increases expression ISO Ascorbic Acid results in increased expression of EIF3I mRNA CTD PMID:22139585 NCBI chr 5:147,796,580...147,803,853
Ensembl chr 5:147,796,662...147,803,851
JBrowse link
G Eif4a1 eukaryotic translation initiation factor 4A1 decreases expression ISO Ascorbic Acid results in decreased expression of EIF4A1 mRNA CTD PMID:19197388 NCBI chr10:56,271,257...56,276,764
Ensembl chr10:56,271,257...56,276,764
JBrowse link
G Elp6 elongator acetyltransferase complex subunit 6 multiple interactions
decreases expression
ISO [arsenic trioxide co-treated with Ascorbic Acid] results in decreased expression of ELP6 mRNA
Ascorbic Acid results in decreased expression of ELP6 mRNA
CTD PMID:25555879 NCBI chr 8:118,525,770...118,541,074
Ensembl chr 8:118,525,682...118,541,073
JBrowse link
G Emp1 epithelial membrane protein 1 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in increased expression of EMP1 mRNA CTD PMID:17639512 NCBI chr 4:169,161,076...169,181,967
Ensembl chr 4:169,147,243...169,181,966
JBrowse link
G Emp3 epithelial membrane protein 3 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in increased expression of EMP3 mRNA CTD PMID:17639512 NCBI chr 1:101,900,731...101,903,948
Ensembl chr 1:101,900,733...101,903,910
JBrowse link
G En1 engrailed homeobox 1 multiple interactions ISO Ascorbic Acid inhibits the reaction [Benzo(a)pyrene results in decreased expression of EN1 mRNA]; Ascorbic Acid inhibits the reaction [Benzo(a)pyrene results in increased methylation of EN1 promoter] CTD PMID:27901495 NCBI chr13:36,532,758...36,537,888
Ensembl chr13:36,532,758...36,537,093
JBrowse link
G Epas1 endothelial PAS domain protein 1 multiple interactions ISO Ascorbic Acid inhibits the reaction [nickel sulfate results in increased expression of EPAS1 protein] CTD PMID:16288478 NCBI chr 6:10,306,508...10,385,239
Ensembl chr 6:10,306,405...10,387,265
JBrowse link
G Ephx1 epoxide hydrolase 1 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in decreased expression of EPHX1 mRNA CTD PMID:17639512 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link
G Ephx2 epoxide hydrolase 2 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in decreased expression of EPHX2 mRNA CTD PMID:17639512 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279
JBrowse link
G Eprs glutamyl-prolyl-tRNA synthetase decreases expression ISO Ascorbic Acid results in decreased expression of EPRS1 mRNA CTD PMID:19197388 NCBI chr13:103,300,911...103,371,651
Ensembl chr13:103,300,932...103,371,577
JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit multiple interactions ISO [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of ERCC2 mRNA CTD PMID:17917374 NCBI chr 1:80,293,574...80,307,334
Ensembl chr 1:80,293,566...80,307,344
JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit multiple interactions ISO [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of ERCC4 mRNA CTD PMID:17917374 NCBI chr10:2,010,140...2,037,953
Ensembl chr10:2,010,648...2,037,891
JBrowse link
G Ercc5 ERCC excision repair 5, endonuclease multiple interactions ISO [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of ERCC5 mRNA CTD PMID:17917374 NCBI chr 9:50,928,847...50,970,962
Ensembl chr 9:50,925,619...50,970,955
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions EXP Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of ESR1 mRNA] CTD PMID:18602937 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions EXP Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of ESR2 mRNA] CTD PMID:18602937 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Ezh1 enhancer of zeste 1 polycomb repressive complex 2 subunit multiple interactions ISO [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of EZH1 mRNA CTD PMID:26424790 NCBI chr10:89,104,026...89,139,978
Ensembl chr10:89,104,027...89,130,339
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit multiple interactions ISO [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of EZH2 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of EZH2 protein; EZH2 protein inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of ALPL mRNA]; EZH2 protein inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of RUNX2 mRNA]; EZH2 protein inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of SATB2 mRNA]; EZH2 protein inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of TNFRSF11B mRNA] CTD PMID:26424790 NCBI chr 4:77,284,404...77,347,011
Ensembl chr 4:77,284,404...77,347,011
JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions ISO Ascorbic Acid inhibits the reaction [Norepinephrine results in increased expression of F3 mRNA] CTD PMID:23114885 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
JBrowse link
G Fabp4 fatty acid binding protein 4 multiple interactions ISO [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with Firemaster 550] results in increased expression of FABP4 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with triphenyl phosphate] results in increased expression of FABP4 mRNA; d,d-T80-prallethrin promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]; Pioglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]; Rosiglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]; tetrabromobisphenol A promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]; triphenyltin hydroxide promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA] CTD PMID:25062436, PMID:25932594, PMID:32473317 NCBI chr 2:93,792,666...93,797,267
Ensembl chr 2:93,792,601...93,797,305
JBrowse link
G Fabp6 fatty acid binding protein 6 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in decreased expression of FABP6 mRNA CTD PMID:17639512 NCBI chr10:29,191,621...29,196,593
Ensembl chr10:29,191,623...29,196,563
JBrowse link
G Fancl FA complementation group L multiple interactions ISO [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of FANCL mRNA CTD PMID:26424790 NCBI chr14:110,675,306...110,740,880
Ensembl chr14:110,676,090...110,740,317
JBrowse link
G Fat1 FAT atypical cadherin 1 multiple interactions
increases expression
ISO [arsenic trioxide co-treated with Ascorbic Acid] results in increased expression of FAT1 mRNA
Ascorbic Acid results in increased expression of FAT1 mRNA
CTD PMID:25555879 NCBI chr16:50,372,150...50,501,716
Ensembl chr16:50,372,128...50,501,921
JBrowse link
G Fbln1 fibulin 1 increases expression
multiple interactions
ISO Ascorbic Acid results in increased expression of FBLN1 mRNA
[arsenic trioxide co-treated with Ascorbic Acid] results in increased expression of FBLN1 mRNA
CTD PMID:25555879 NCBI chr 7:126,096,793...126,176,468
Ensembl chr 7:126,096,793...126,176,468
JBrowse link
G Fbp1 fructose-bisphosphatase 1 affects expression ISO Ascorbic Acid affects the expression of FBP1 protein CTD PMID:19224539 NCBI chr17:396,175...417,480
Ensembl chr17:396,180...417,480
JBrowse link
G Fdxr ferredoxin reductase increases expression EXP Ascorbic Acid results in increased expression of FDXR mRNA CTD PMID:15372504 NCBI chr10:103,817,724...103,826,413
Ensembl chr10:103,817,704...103,826,448
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 decreases expression ISO Ascorbic Acid results in decreased expression of FLT1 mRNA CTD PMID:21919647 NCBI chr12:9,033,993...9,205,886
Ensembl chr12:9,034,308...9,205,905
JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in decreased expression of FMO1 mRNA CTD PMID:17639512 NCBI chr13:80,712,885...80,745,095
Ensembl chr13:80,712,882...80,745,347
JBrowse link
G Fmo5 flavin containing dimethylaniline monoxygenase 5 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in decreased expression of FMO5 mRNA CTD PMID:17639512 NCBI chr 2:199,796,870...199,823,927
Ensembl chr 2:199,796,881...199,823,927
JBrowse link
G Fmr1 FMRP translational regulator 1 multiple interactions ISO Ascorbic Acid inhibits the reaction [FMR1 5' UTR mutant form results in decreased activity of CS protein] CTD PMID:27385396 NCBI chr  X:154,684,924...154,722,369
Ensembl chr  X:154,684,935...154,722,314
JBrowse link
G Fn1 fibronectin 1 multiple interactions ISO [Ascorbic Acid co-treated with Quartz] results in increased expression of FN1 mRNA; [Tretinoin co-treated with Ascorbic Acid] results in increased expression of FN1 mRNA CTD PMID:16443354, PMID:27381660 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Fn3krp fructosamine-3-kinase-related protein increases expression ISO Ascorbic Acid results in increased expression of FN3KRP mRNA CTD PMID:25555879 NCBI chr10:110,614,739...110,622,625
Ensembl chr10:110,614,713...110,623,519
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO Ascorbic Acid results in increased expression of FOS mRNA CTD PMID:15305145 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Foxa2 forkhead box A2 multiple interactions EXP Ascorbic Acid inhibits the reaction [nitrofen results in decreased expression of FOXA2 protein] CTD PMID:16863852 NCBI chr 3:142,383,084...142,387,493
Ensembl chr 3:142,383,278...142,387,481
JBrowse link
G Foxj1 forkhead box J1 multiple interactions
increases expression
ISO
EXP
[Tretinoin co-treated with Ascorbic Acid] results in increased expression of FOXJ1 mRNA
Ascorbic Acid results in increased expression of FOXJ1 mRNA
CTD PMID:15372504, PMID:16443354 NCBI chr10:105,282,090...105,289,396 JBrowse link
G Fshb follicle stimulating hormone subunit beta multiple interactions EXP Ascorbic Acid inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of FSHB protein]; Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in increased expression of FSHB protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in increased expression of FSHB protein] CTD PMID:16248992, PMID:17280759, PMID:18602937, PMID:23470461 NCBI chr 3:98,088,321...98,092,131
Ensembl chr 3:98,088,324...98,092,131
JBrowse link
G Fshr follicle stimulating hormone receptor multiple interactions EXP Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of FSHR mRNA]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of FSHR mRNA]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of FSHR protein] CTD PMID:18602937, PMID:23470461 NCBI chr 6:12,796,383...12,997,817
Ensembl chr 6:12,796,383...12,997,817
JBrowse link
G Fth1 ferritin heavy chain 1 increases expression EXP Ascorbic Acid results in increased expression of FTH1 mRNA CTD PMID:15372504 NCBI chr 1:226,030,940...226,033,228
Ensembl chr 1:226,030,938...226,033,228
JBrowse link
G Ftl1 ferritin light chain 1 affects expression ISO Ascorbic Acid affects the expression of FTL protein CTD PMID:19224539 NCBI chr 1:101,448,190...101,450,034
Ensembl chr 1:101,448,346...101,449,829
JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase multiple interactions ISO Ascorbic Acid inhibits the reaction [bis(2-hydroxy-2-ethylbutanoato)oxochromate(V) results in increased phosphorylation of FYN protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in increased phosphorylation of FYN protein] CTD PMID:14572611 NCBI chr20:44,436,354...44,630,316
Ensembl chr20:44,436,403...44,630,317
JBrowse link
G Fzd2 frizzled class receptor 2 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in increased expression of FZD2 mRNA CTD PMID:17639512 NCBI chr10:90,550,147...90,552,057
Ensembl chr10:90,550,147...90,552,057
JBrowse link
G G0s2 G0/G1switch 2 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in decreased expression of G0S2 mRNA CTD PMID:17639512 NCBI chr13:112,004,140...112,005,052
Ensembl chr13:112,004,140...112,005,052
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase multiple interactions ISO Ascorbic Acid inhibits the reaction [Cadmium Chloride results in decreased activity of G6PD protein] CTD PMID:18548748 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gabarap GABA type A receptor-associated protein increases expression ISO Ascorbic Acid results in increased expression of GABARAP mRNA CTD PMID:15305145 NCBI chr10:56,601,288...56,604,223
Ensembl chr10:56,601,288...56,604,221
JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta multiple interactions EXP [Ascorbic Acid co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of GADD45B mRNA CTD PMID:18544905 NCBI chr 7:11,646,283...11,648,338
Ensembl chr 7:11,646,269...11,648,322
JBrowse link
G Gak cyclin G associated kinase multiple interactions ISO [Tretinoin co-treated with Ascorbic Acid] results in decreased expression of GAK mRNA CTD PMID:16443354 NCBI chr14:2,100,104...2,174,332
Ensembl chr14:2,100,106...2,174,318
JBrowse link
G Gal galanin and GMAP prepropeptide multiple interactions EXP [ferulic acid co-treated with Ascorbic Acid] inhibits the reaction [Isoproterenol results in increased activity of GAL protein] CTD PMID:17045618 NCBI chr 1:218,653,059...218,657,922
Ensembl chr 1:218,652,917...218,657,925
JBrowse link
G Gamt guanidinoacetate N-methyltransferase affects expression ISO Ascorbic Acid affects the expression of GAMT protein CTD PMID:19224539 NCBI chr 7:12,314,848...12,317,998
Ensembl chr 7:12,314,848...12,317,998
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase increases expression ISO Ascorbic Acid results in increased expression of GAPDH protein CTD PMID:22139585 NCBI chr 4:157,676,336...157,680,322
Ensembl chr 4:157,676,595...157,679,962
JBrowse link
G Gars glycyl-tRNA synthetase decreases expression ISO Ascorbic Acid results in decreased expression of GARS1 mRNA CTD PMID:19197388 NCBI chr 4:85,235,122...85,276,085
Ensembl chr 4:85,235,172...85,276,044
JBrowse link
G Gas7 growth arrest specific 7 increases expression ISO Ascorbic Acid results in increased expression of GAS7 mRNA CTD PMID:15305145 NCBI chr10:54,010,723...54,240,805
Ensembl chr10:54,126,486...54,236,476
JBrowse link
G Gata1 GATA binding protein 1 multiple interactions ISO [Tretinoin co-treated with Ascorbic Acid] results in increased expression of GATA1 mRNA CTD PMID:16443354 NCBI chr  X:15,273,937...15,281,759
Ensembl chr  X:15,378,789...15,382,066
JBrowse link
G Gata4 GATA binding protein 4 increases expression ISO Ascorbic Acid results in increased expression of GATA4 mRNA CTD PMID:12668514 NCBI chr15:46,386,703...46,458,679
Ensembl chr15:46,386,712...46,432,965
JBrowse link
G Gbp2 guanylate binding protein 2 increases expression EXP Ascorbic Acid results in increased expression of GBP2 mRNA CTD PMID:15372504 NCBI chr 2:248,276,795...248,293,784
Ensembl chr 2:248,276,709...248,293,784
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions EXP [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of GCLC mRNA; Ascorbic Acid inhibits the reaction [Ethylene Chlorohydrin results in increased expression of GCLC mRNA]; Ascorbic Acid inhibits the reaction [Ethylene Chlorohydrin results in increased expression of GCLC protein]; Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of GCLC mRNA]; Quercetin affects the reaction [Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of GCLC mRNA]] CTD PMID:27028516, PMID:31585129 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gdf10 growth differentiation factor 10 multiple interactions EXP [Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of GDF10 mRNA CTD PMID:15994055 NCBI chr16:10,250,508...10,262,383
Ensembl chr16:10,250,404...10,263,150
JBrowse link
G Gfap glial fibrillary acidic protein decreases expression EXP Ascorbic Acid results in decreased expression of GFAP protein CTD PMID:15372504 NCBI chr10:90,990,762...90,999,435
Ensembl chr10:90,990,762...90,999,506
JBrowse link
G Gfra1 GDNF family receptor alpha 1 multiple interactions ISO [Tretinoin co-treated with Ascorbic Acid] results in increased expression of GFRA1 mRNA CTD PMID:16443354 NCBI chr 1:279,203,046...279,572,789 JBrowse link
G Ggt1 gamma-glutamyltransferase 1 multiple interactions EXP Ascorbic Acid inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased activity of GGT1 protein] CTD PMID:16298753 NCBI chr20:14,019,723...14,045,781
Ensembl chr20:14,019,723...14,025,068
JBrowse link
G Gh1 growth hormone 1 multiple interactions EXP Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of GH1 protein] CTD PMID:18602937 NCBI chr10:94,486,204...94,488,181
Ensembl chr10:94,486,205...94,488,180
JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions EXP [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of GJA1 protein]; [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of GJA1 protein] CTD PMID:29940330 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Glo1 glyoxalase 1 affects expression ISO Ascorbic Acid affects the expression of GLO1 protein CTD PMID:19224539 NCBI chr20:9,273,589...9,291,608
Ensembl chr20:9,273,594...9,291,610
JBrowse link
G Glrx glutaredoxin multiple interactions EXP Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of GLRX mRNA] CTD PMID:23470461 NCBI chr 2:2,606,032...2,615,944
Ensembl chr 2:2,605,996...2,615,944
JBrowse link
G Gls glutaminase multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in decreased expression of GLS mRNA CTD PMID:17639512 NCBI chr 9:54,212,622...54,284,879
Ensembl chr 9:54,212,767...54,284,872
JBrowse link
G Gng3 G protein subunit gamma 3 increases expression ISO Ascorbic Acid results in increased expression of GNG3 mRNA CTD PMID:15305145 NCBI chr 1:225,033,921...225,035,687
Ensembl chr 1:225,033,921...225,035,687
JBrowse link
G Gng4 G protein subunit gamma 4 increases expression ISO Ascorbic Acid results in increased expression of GNG4 mRNA CTD PMID:15305145 NCBI chr17:90,266,571...90,316,278
Ensembl chr17:90,266,794...90,315,492
JBrowse link
G Gpat3 glycerol-3-phosphate acyltransferase 3 increases expression ISO Ascorbic Acid results in increased expression of GPAT3 mRNA CTD PMID:26198647 NCBI chr14:10,343,287...10,396,565
Ensembl chr14:10,343,282...10,395,047
JBrowse link
G Gpc1 glypican 1 multiple interactions
increases expression
increases degradation
ISO [Ascorbic Acid co-treated with Nitric Oxide] results in increased degradation of GPC1 protein modified form; Zinc promotes the reaction [[Ascorbic Acid co-treated with Nitric Oxide] results in increased degradation of GPC1 protein modified form]
Ascorbic Acid results in increased expression of GPC1 mRNA
Ascorbic Acid results in increased degradation of GPC1 protein
CTD PMID:15677459, PMID:21642435, PMID:25555879 NCBI chr 9:99,998,275...100,026,818
Ensembl chr 9:99,998,275...100,026,818
JBrowse link
G Gpc3 glypican 3 multiple interactions ISO [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of GPC3 mRNA; cadmium sulfate inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of GPC3 mRNA] CTD PMID:28189605 NCBI chr  X:139,579,268...139,947,093
Ensembl chr  X:139,579,268...139,916,883
JBrowse link
G Gpd1 glycerol-3-phosphate dehydrogenase 1 multiple interactions EXP [Ascorbic Acid co-treated with INS1 protein] results in decreased expression of GPD1 mRNA CTD PMID:20400526 NCBI chr 7:141,368,928...141,377,931
Ensembl chr 7:141,370,491...141,377,928
JBrowse link
G Gpn1 GPN-loop GTPase 1 multiple interactions
decreases expression
ISO [arsenic trioxide co-treated with Ascorbic Acid] results in decreased expression of GPN1 mRNA
Ascorbic Acid results in decreased expression of GPN1 mRNA
CTD PMID:25555879 NCBI chr 6:26,255,081...26,272,755
Ensembl chr 6:26,242,925...26,272,808
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP Ascorbic Acid inhibits the reaction [Cyclosporine results in increased activity of GPT protein]; Ascorbic Acid inhibits the reaction [Food Additives results in increased activity of GPT protein] CTD PMID:16758767, PMID:19391111 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions
increases expression
ISO
EXP
[Ascorbic Acid co-treated with Vitamin E] results in increased expression of GPX1 mRNA; [Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of GPX1 mRNA; [Vitamin A co-treated with Ascorbic Acid co-treated with Vitamin E] results in increased expression of GPX1 protein; Ascorbic Acid inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of GPX1 mRNA]; nutlin 3 inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of GPX1 mRNA]
Ascorbic Acid results in increased expression of GPX1 mRNA
[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in increased expression of GPX1 protein]; Ascorbic Acid inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased activity of GPX1 protein]
CTD PMID:15372504, PMID:16248992, PMID:16298753, PMID:17179735, PMID:20530418, PMID:22207723, PMID:29663635, PMID:31576639, PMID:31610155 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gpx2 glutathione peroxidase 2 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in increased expression of GPX2 mRNA; [Tretinoin co-treated with Ascorbic Acid] results in increased expression of GPX2 mRNA CTD PMID:16443354, PMID:17639512 NCBI chr 6:99,839,960...99,843,245
Ensembl chr 6:99,839,960...99,843,245
JBrowse link
G Gpx4 glutathione peroxidase 4 increases expression EXP Ascorbic Acid results in increased expression of GPX4 mRNA CTD PMID:15372504 NCBI chr 7:12,516,357...12,519,154
Ensembl chr 7:12,516,352...12,519,154
JBrowse link
G Grn granulin precursor increases expression
multiple interactions
ISO Ascorbic Acid results in increased expression of GRN mRNA
[arsenic trioxide co-treated with Ascorbic Acid] results in increased expression of GRN mRNA
CTD PMID:25555879 NCBI chr10:90,377,103...90,383,207
Ensembl chr10:90,376,933...90,383,205
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases expression
multiple interactions
EXP Ascorbic Acid results in decreased expression of GSK3B mRNA
Ascorbic Acid inhibits the reaction [Excitatory Amino Acid Agonists results in increased phosphorylation of GSK3B protein]
CTD PMID:15372504, PMID:24675465 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions ISO
EXP
[Ascorbic Acid co-treated with GSR protein] affects the metabolism of Glucose; [juglone co-treated with Ascorbic Acid] results in decreased activity of GSR protein
Ascorbic Acid inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased activity of GSR protein]; Ascorbic Acid inhibits the reaction [bisphenol A results in decreased activity of GSR protein]; Ascorbic Acid inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased activity of GSR protein]; Ascorbic Acid inhibits the reaction [Cyclosporine results in decreased activity of GSR protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased activity of GSR protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of GSR mRNA]; Ascorbic Acid inhibits the reaction [sodium arsenite results in decreased activity of GSR protein]; Ascorbic Acid inhibits the reaction [sodium arsenite results in decreased expression of GSR protein]
[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of GSR mRNA; Ascorbic Acid inhibits the reaction [arsenic trioxide results in decreased activity of GSR protein]; Ascorbic Acid inhibits the reaction [Cadmium Chloride results in decreased activity of GSR protein]
CTD PMID:1901343, PMID:12767684, PMID:16248992, PMID:16298753, PMID:17917374, PMID:18548748, PMID:18715643, PMID:19391111, PMID:19429265, PMID:23194016, PMID:23470461, PMID:29992683, PMID:32407874 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in decreased expression of GSTA1 mRNA CTD PMID:17639512 NCBI chr 9:27,366,404...27,381,004
Ensembl chr 9:27,368,272...27,452,902
JBrowse link
G Gsta4 glutathione S-transferase alpha 4 multiple interactions EXP Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of GSTA4 mRNA] CTD PMID:23470461 NCBI chr 8:85,497,557...85,514,732
Ensembl chr 8:85,497,557...85,518,879
JBrowse link
G Gsta5 glutathione S-transferase alpha 5 multiple interactions ISO Ascorbic Acid promotes the reaction [sodium arsenite results in increased expression of GSTA1 mRNA] CTD PMID:16517059 NCBI chr 8:85,553,659...85,564,914
Ensembl chr 8:85,553,734...85,565,179
JBrowse link
G Gstm1 glutathione S-transferase mu 1 affects response to substance
multiple interactions
ISO
EXP
GSTM1 affects the susceptibility to Ascorbic Acid deficiency
Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of GSTM1 mRNA]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of GSTM1 mRNA]
GSTM1 gene polymorphism affects the susceptibility to [Ascorbic Acid co-treated with tocotrienol, alpha]
CTD PMID:15668500, PMID:19710200, PMID:23470461 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstm2 glutathione S-transferase mu 2 multiple interactions
increases expression
EXP Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of GSTM2 mRNA]
Ascorbic Acid results in increased expression of GSTM2 mRNA
CTD PMID:15372504, PMID:23470461 NCBI chr 2:210,778,041...210,782,807
Ensembl chr 2:210,720,704...210,782,856
JBrowse link
G Gsto1 glutathione S-transferase omega 1 increases expression
multiple interactions
ISO Ascorbic Acid results in increased expression of GSTO1 mRNA
Ascorbic Acid inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of GSTO1 mRNA]
CTD PMID:31610155 NCBI chr 1:267,607,437...267,617,387
Ensembl chr 1:267,607,418...267,617,387
JBrowse link
G Gstt1 glutathione S-transferase theta 1 affects response to substance ISO GSTT1 affects the susceptibility to Ascorbic Acid deficiency CTD PMID:19710200 NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526
JBrowse link
G Gtf2h1 general transcription factor IIH subunit 1 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in decreased expression of GTF2H1 mRNA CTD PMID:17639512 NCBI chr 1:102,849,618...102,877,939
Ensembl chr 1:102,849,889...102,877,944
JBrowse link
G Gucy1b1 guanylate cyclase 1 soluble subunit beta 1 multiple interactions EXP Ascorbic Acid inhibits the reaction [lead acetate results in decreased expression of GUCY1B1 protein] CTD PMID:11729227 NCBI chr 2:180,976,939...181,026,001
Ensembl chr 2:180,976,939...181,026,024
JBrowse link
G Gusb glucuronidase, beta multiple interactions EXP [ferulic acid co-treated with Ascorbic Acid] inhibits the reaction [Isoproterenol results in increased activity of GUSB protein] CTD PMID:17045618 NCBI chr12:30,202,066...30,215,583
Ensembl chr12:30,198,822...30,227,771
JBrowse link
G Gzmb granzyme B decreases expression ISO Ascorbic Acid deficiency results in decreased expression of GZMB mRNA CTD PMID:22306178 NCBI chr15:35,413,862...35,417,293
Ensembl chr15:35,413,793...35,417,316
JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of H2AX mRNA; [Ascorbic Acid results in increased reduction of Vitamin K 3] which results in increased phosphorylation of H2AX protein CTD PMID:19482829, PMID:26424790 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha decreases expression EXP Ascorbic Acid results in decreased expression of HADHA mRNA CTD PMID:15372504 NCBI chr 6:27,589,840...27,628,921
Ensembl chr 6:27,589,657...27,629,175
JBrowse link
G Hand2 heart and neural crest derivatives expressed 2 multiple interactions ISO [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of HAND2 mRNA; cadmium sulfate inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of HAND2 mRNA] CTD PMID:28189605 NCBI chr16:36,371,489...36,373,551
Ensembl chr16:36,371,489...36,373,546
JBrowse link
G Hcfc1 host cell factor C1 multiple interactions
increases expression
ISO [arsenic trioxide co-treated with Ascorbic Acid] results in increased expression of HCFC1 mRNA
Ascorbic Acid results in increased expression of HCFC1 mRNA
CTD PMID:25555879 NCBI chr  X:156,812,012...156,837,227
Ensembl chr  X:156,812,064...156,837,227
JBrowse link
G Hells helicase, lymphoid specific multiple interactions ISO [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of HELLS mRNA CTD PMID:26424790 NCBI chr 1:257,901,856...257,953,889
Ensembl chr 1:257,766,691...257,949,183
Ensembl chr 1:257,766,691...257,949,183
JBrowse link
G Heph hephaestin multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in decreased expression of HEPH mRNA CTD PMID:17639512 NCBI chr  X:65,377,313...65,658,479
Ensembl chr  X:65,563,122...65,658,516
JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 decreases expression ISO Ascorbic Acid results in decreased expression of HERPUD1 mRNA CTD PMID:19197388 NCBI chr19:11,046,905...11,057,440
Ensembl chr19:11,046,909...11,057,254
JBrowse link
G Hes1 hes family bHLH transcription factor 1 multiple interactions EXP [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of HES1 protein] CTD PMID:29663635 NCBI chr11:74,312,837...74,315,249
Ensembl chr11:74,312,806...74,315,248
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases degradation
multiple interactions
ISO
EXP
Ascorbic Acid results in increased degradation of HIF1A protein
Ascorbic Acid inhibits the reaction [AGT protein modified form results in decreased hydroxylation of HIF1A protein]; Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in decreased hydroxylation of HIF1A protein]
[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Ketoglutaric Acids co-treated with Ascorbic Acid co-treated with ferrous chloride] promotes the reaction [VHL protein binds to HIF1A protein]; Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in increased stability of HIF1A protein]; Ascorbic Acid inhibits the reaction [cupric chloride results in decreased hydroxylation of HIF1A protein]; Ascorbic Acid inhibits the reaction [cupric chloride results in increased stability of HIF1A protein]; Ascorbic Acid inhibits the reaction [manganese chloride results in decreased hydroxylation of HIF1A protein]; Ascorbic Acid inhibits the reaction [manganese chloride results in increased stability of HIF1A protein]; Ascorbic Acid inhibits the reaction [nickel sulfate results in decreased hydroxylation of HIF1A protein]; Ascorbic Acid inhibits the reaction [nickel sulfate results in increased expression of HIF1A protein]; Ascorbic Acid inhibits the reaction [nickel sulfate results in increased stability of HIF1A protein]; Ascorbic Acid inhibits the reaction [potassium chromate(VI) results in increased stability of HIF1A protein]; Ascorbic Acid inhibits the reaction [Quercetin results in increased expression of HIF1A protein]; Ascorbic Acid inhibits the reaction [sodium arsenite results in decreased hydroxylation of HIF1A protein]; Ascorbic Acid inhibits the reaction [sodium arsenite results in increased expression of HIF1A protein]; Ascorbic Acid inhibits the reaction [sodium arsenite results in increased stability of HIF1A protein]; Ascorbic Acid inhibits the reaction [Vanadates results in decreased hydroxylation of HIF1A protein]; Ascorbic Acid inhibits the reaction [Vanadates results in increased stability of HIF1A protein]; manganese chloride inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Ketoglutaric Acids co-treated with Ascorbic Acid co-treated with ferrous chloride] promotes the reaction [VHL protein binds to HIF1A protein]]
CTD PMID:16288478, PMID:17364964, PMID:17382205, PMID:19074761, PMID:19263519, PMID:20881940, PMID:24188932 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hist1h2bd histone cluster 1 H2B family member D multiple interactions ISO [Arsenic Trioxide co-treated with Ascorbic Acid] results in decreased expression of H2BC5 mRNA CTD PMID:25555879 NCBI chr17:44,833,924...44,834,305
Ensembl chr17:44,833,924...44,834,305
JBrowse link
G Hk1 hexokinase 1 multiple interactions ISO [Tretinoin co-treated with Ascorbic Acid] results in increased expression of HK1 mRNA CTD PMID:16443354 NCBI chr20:31,911,460...31,979,780
Ensembl chr20:31,912,262...31,956,649
JBrowse link
G Hlcs holocarboxylase synthetase decreases activity ISO Ascorbic Acid results in decreased activity of HLCS protein CTD PMID:26303405 NCBI chr11:34,357,372...34,537,798
Ensembl chr11:34,352,287...34,526,931
JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions ISO [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of HMGB1 mRNA CTD PMID:26424790 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Hmgb2 high mobility group box 2 multiple interactions ISO [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of HMGB2 mRNA CTD PMID:26424790 NCBI chr16:36,077,615...36,080,191
Ensembl chr16:36,077,617...36,080,191
Ensembl chr11:36,077,617...36,080,191
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO
EXP
Ascorbic Acid results in increased expression of HMOX1 mRNA
[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in increased expression of HMOX1 protein]; [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of HMOX1 mRNA; [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of HMOX1 protein; Ascorbic Acid inhibits the reaction [Ethylene Chlorohydrin results in increased expression of HMOX1 mRNA]; Ascorbic Acid inhibits the reaction [Ethylene Chlorohydrin results in increased expression of HMOX1 protein]; Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of HMOX1 mRNA]; Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of HMOX1 protein]; Hydrogen Peroxide affects the reaction [Quercetin affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of HMOX1 mRNA]]; Hydrogen Peroxide affects the reaction [Quercetin affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of HMOX1 protein]]; Methamphetamine promotes the reaction [Ascorbic Acid results in increased expression of HMOX1 mRNA]; Methamphetamine promotes the reaction [Ascorbic Acid results in increased expression of HMOX1 protein]; Quercetin affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of HMOX1 mRNA]; Quercetin affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of HMOX1 protein]; Quercetin affects the reaction [Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of HMOX1 protein]]; SB 203580 inhibits the reaction [Ascorbic Acid results in increased expression of HMOX1 protein]
Ascorbic Acid results in increased expression of HMOX1 mRNA; Ascorbic Acid results in increased expression of HMOX1 protein
[Buthionine Sulfoximine co-treated with Ascorbic Acid] promotes the reaction [Copper Sulfate results in increased expression of HMOX1 mRNA]; Ascorbic Acid inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of HMOX1 mRNA]; Ascorbic Acid inhibits the reaction [benzo(a)pyrene-7,8-dione results in increased expression of HMOX1 protein]; Ascorbic Acid inhibits the reaction [HMOX1 protein results in increased expression of SOD2 mRNA]; Ascorbic Acid inhibits the reaction [Resveratrol results in increased expression of HMOX1 mRNA]; Ascorbic Acid inhibits the reaction [Resveratrol results in increased expression of HMOX1 protein]; Ascorbic Acid promotes the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of HMOX1 mRNA]
Ascorbic Acid inhibits the reaction [Cadmium Chloride results in increased expression of HMOX1 mRNA]; Ascorbic Acid inhibits the reaction [Cadmium results in increased expression of HMOX1 mRNA]; Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in increased expression of HMOX1 mRNA]; Ascorbic Acid inhibits the reaction [Nelfinavir results in increased expression of HMOX1]; Ascorbic Acid promotes the reaction [sodium arsenite results in increased expression of HMOX1 mRNA]
CTD PMID:8743975, PMID:10942521, PMID:15577407, PMID:16171798, PMID:16517059, PMID:19683516, PMID:21199573, PMID:22008531, PMID:22053912, PMID:23022510, PMID:27028516, PMID:29663635, PMID:29940330, PMID:31585129, PMID:31610155, PMID:32525552 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hoxa2 homeobox A2 multiple interactions ISO Ascorbic Acid inhibits the reaction [Valproic Acid results in decreased expression of HOXA2 mRNA] CTD PMID:19655241 NCBI chr 4:82,130,441...82,134,846
Ensembl chr 4:82,131,329...82,133,605
JBrowse link
G Hp haptoglobin affects activity
affects response to substance
multiple interactions
ISO Ascorbic Acid affects the activity of HP protein polymorphism
HP gene polymorphism affects the susceptibility to Ascorbic Acid deficiency
Ascorbic Acid inhibits the reaction [alpha-Tocopherol affects the activity of HP protein polymorphism]
CTD PMID:19769483, PMID:20926521 NCBI chr19:42,096,255...42,100,805
Ensembl chr19:42,097,995...42,100,804
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 multiple interactions EXP Ascorbic Acid inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased mutagenesis of HPRT1 gene] CTD PMID:12467141 NCBI chr  X:158,196,640...158,228,815
Ensembl chr  X:158,197,149...158,228,749
JBrowse link
G Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 multiple interactions EXP Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of HSD17B1 mRNA] CTD PMID:18602937 NCBI chr10:88,987,558...88,989,758
Ensembl chr10:88,987,558...88,989,757
JBrowse link
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 multiple interactions EXP Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of HSD17B2 mRNA] CTD PMID:18602937 NCBI chr19:50,246,404...50,317,892
Ensembl chr19:50,246,402...50,317,891
JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 multiple interactions EXP Ascorbic Acid inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of HSD17B3 mRNA] CTD PMID:17280759 NCBI chr17:1,579,319...1,610,745
Ensembl chr17:1,579,319...1,610,745
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 multiple interactions
increases expression
EXP
ISO
Ascorbic Acid inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of HSD3B1 mRNA]
Ascorbic Acid results in increased expression of HSD3B1 mRNA
CTD PMID:17280759, PMID:17901237
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 affects expression ISO Ascorbic Acid affects the expression of HSP90AB1 protein CTD PMID:19224539 NCBI chr 9:17,817,791...17,823,163
Ensembl chr 9:17,817,721...17,823,243
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in increased expression of HSPA1A mRNA CTD PMID:17639512 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions
decreases expression
ISO Ascorbic Acid inhibits the reaction [Fenretinide results in increased expression of HSPA5 protein]
Ascorbic Acid results in decreased expression of HSPA5 mRNA
CTD PMID:17353921, PMID:19197388 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 decreases expression ISO Ascorbic Acid results in decreased expression of HSPA9 mRNA CTD PMID:19197388 NCBI chr18:27,731,072...27,749,235
Ensembl chr18:27,731,072...27,749,235
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 multiple interactions
increases expression
ISO
EXP
[Quercetin co-treated with Ascorbic Acid] results in increased expression of HSPB1 mRNA
Ascorbic Acid results in increased expression of HSPB1 mRNA
CTD PMID:15372504, PMID:17639512 NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 multiple interactions ISO [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of HSPE1 mRNA CTD PMID:17917374 NCBI chr 9:61,691,246...61,724,948
Ensembl chr 9:61,692,154...61,694,599
JBrowse link
G Iapp islet amyloid polypeptide multiple interactions EXP IAPP protein promotes the reaction [[Copper co-treated with Ascorbic Acid] results in increased abundance of Hydrogen Peroxide]; IAPP protein promotes the reaction [[Copper co-treated with Ascorbic Acid] results in increased abundance of Hydroxyl Radical] CTD PMID:23793354 NCBI chr 4:176,509,863...176,517,903
Ensembl chr 4:176,510,696...176,516,083
JBrowse link
G Iars1 isoleucyl-tRNA synthetase 1 decreases expression ISO Ascorbic Acid results in decreased expression of IARS1 mRNA CTD PMID:19197388 NCBI chr17:15,356,016...15,402,680
Ensembl chr17:15,355,529...15,402,649
JBrowse link
G Ibsp integrin-binding sialoprotein multiple interactions
increases expression
EXP
ISO
[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of IBSP mRNA; Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of IBSP mRNA]; Quercetin affects the reaction [Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of IBSP mRNA]]
[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of IBSP mRNA; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of IBSP mRNA]
Ascorbic Acid results in increased expression of IBSP mRNA
CTD PMID:26492236, PMID:27028516, PMID:28105418 NCBI chr14:6,801,200...6,813,987
Ensembl chr14:6,801,204...6,813,945
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of ICAM1 mRNA]; Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of ICAM1 protein]; Ascorbic Acid inhibits the reaction [Norepinephrine results in increased expression of ICAM1 mRNA]; Ascorbic Acid inhibits the reaction [TNF protein results in increased expression of ICAM1 protein] CTD PMID:12723939, PMID:23114885, PMID:25305479, PMID:25551565 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Ier3 immediate early response 3 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in increased expression of IER3 mRNA CTD PMID:17639512 NCBI chr20:3,438,798...3,440,002
Ensembl chr20:3,438,798...3,440,769
JBrowse link
G Ifi27 interferon, alpha-inducible protein 27 increases expression EXP Ascorbic Acid results in increased expression of IFI27 mRNA CTD PMID:15372504 NCBI chr 6:127,327,959...127,334,430
Ensembl chr 6:127,327,959...127,334,428
JBrowse link
G Ifng interferon gamma multiple interactions
decreases expression
ISO
EXP
IFNG protein promotes the reaction [Ascorbic Acid promotes the reaction [Quartz results in increased secretion of TNF protein]]
Ascorbic Acid inhibits the reaction [Formaldehyde results in increased expression of IFNG mRNA]
Ascorbic Acid results in decreased expression of IFNG protein
CTD PMID:14624943, PMID:19298665, PMID:27020608 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Igf1r insulin-like growth factor 1 receptor increases expression ISO Ascorbic Acid results in increased expression of IGF1R protein CTD PMID:20530736 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 multiple interactions ISO
EXP
[Tretinoin co-treated with Ascorbic Acid] results in decreased expression of IGFBP5 mRNA
[alpha-Tocopherol co-treated with beta Carotene co-treated with Ascorbic Acid co-treated with Zinc co-treated with Sodium Selenite] results in decreased expression of IGFBP5 mRNA
CTD PMID:16443354, PMID:23859036 NCBI chr 9:80,154,230...80,166,813
Ensembl chr 9:80,150,211...80,167,033
JBrowse link
G Ihh Indian hedgehog signaling molecule increases expression ISO Ascorbic Acid results in increased expression of IHH mRNA CTD PMID:20530736 NCBI chr 9:82,208,223...82,214,440
Ensembl chr 9:82,208,223...82,214,440
JBrowse link
G Ikzf1 IKAROS family zinc finger 1 multiple interactions
decreases activity
ISO 2-dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole inhibits the reaction [Ascorbic Acid results in decreased activity of IKZF1 protein]; 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole-3',5'-monophosphorothioate inhibits the reaction [Ascorbic Acid results in decreased activity of IKZF1 protein] CTD PMID:17664058 NCBI chr14:91,782,281...91,867,828
Ensembl chr14:91,782,354...91,867,424
JBrowse link
G Il10 interleukin 10 multiple interactions ISO
EXP
[Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] promotes the reaction [TNF protein results in increased expression of and results in increased secretion of IL10 protein]; Ascorbic Acid promotes the reaction [TNF protein results in increased expression of and results in increased secretion of IL10 protein]
Ascorbic Acid inhibits the reaction [Formaldehyde promotes the reaction [Lipopolysaccharides results in increased expression of IL10 mRNA]]
CTD PMID:25551565, PMID:27020608 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO
EXP
Ascorbic Acid inhibits the reaction [IL1B results in increased chemical synthesis of 8-epi-prostaglandin F2alpha]; Ascorbic Acid inhibits the reaction [IL1B results in increased chemical synthesis of Dinoprostone]; Ascorbic Acid promotes the reaction [Aspirin inhibits the reaction [IL1B results in increased chemical synthesis of 8-epi-prostaglandin F2alpha]]; Ascorbic Acid promotes the reaction [Aspirin inhibits the reaction [IL1B results in increased chemical synthesis of Dinoprostone]]; IL1B protein inhibits the reaction [[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in decreased expression of MMP13 mRNA]; IL1B protein inhibits the reaction [[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of ACAN mRNA]; IL1B protein inhibits the reaction [[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of COL2A1 mRNA]; IL1B protein inhibits the reaction [[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of SOX9 mRNA]; IL1B protein results in decreased susceptibility to [TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone]; Resveratrol inhibits the reaction [IL1B protein inhibits the reaction [[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of ACAN mRNA]]; Resveratrol inhibits the reaction [IL1B protein inhibits the reaction [[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of COL2A1 mRNA]]; Resveratrol inhibits the reaction [IL1B protein inhibits the reaction [[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of SOX9 mRNA]]
[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of IL1B mRNA; [Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of IL1B protein; Ascorbic Acid inhibits the reaction [Silicon Dioxide analog promotes the reaction [Lipopolysaccharides results in increased expression of IL1B protein]]; Ascorbic Acid inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of IL1B mRNA]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of IL1B protein]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of IL1B mRNA]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of IL1B protein]
Ascorbic Acid deficiency promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL1B protein]; Ascorbic Acid inhibits the reaction [lead acetate results in increased expression of IL1B protein]; Ascorbic Acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL1B protein]; Ascorbic Acid inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]
CTD PMID:15612528, PMID:16529823, PMID:22728154, PMID:23692848, PMID:24685903, PMID:26526931, PMID:28259689, PMID:30606963 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il4 interleukin 4 decreases expression ISO Ascorbic Acid results in decreased expression of IL4 protein CTD PMID:14624943 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il6 interleukin 6 multiple interactions EXP Ascorbic Acid inhibits the reaction [Formaldehyde inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]]; Ascorbic Acid inhibits the reaction [lead acetate results in increased expression of IL6 protein] CTD PMID:22728154, PMID:27020608 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Ins2 insulin 2 multiple interactions ISO [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of ABCA1 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of CEBPA mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of DMP1 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of NR1H3 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PPARG mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA; [Bexarotene co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 protein; [Copper co-treated with Ascorbic Acid] results in increased oxidation of and affects the folding of INS protein; [diazepinylbenzoic acid co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in decreased expression of ABCA1 mRNA; [LG 100268 co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA; [Rosiglitazone co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 protein; [TO-901317 co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA; [tributyltin co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA; [tributyltin co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 protein; Bexarotene inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; Bexarotene inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of DMP1 mRNA]; Bexarotene inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; Bexarotene promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of NR1H3 mRNA]; Bexarotene promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA]; diazepinylbenzoic acid inhibits the reaction [[LG 100268 co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA]; diazepinylbenzoic acid inhibits the reaction [[tributyltin co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA]; Rosiglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; Rosiglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of DMP1 mRNA]; Rosiglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; Rosiglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of NR1H3 mRNA]; Rosiglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA]; tributyltin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; tributyltin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of DMP1 mRNA]; tributyltin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; tributyltin promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of NR1H3 mRNA]; tributyltin promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA]; Trientine inhibits the reaction [[Copper co-treated with Ascorbic Acid] results in increased oxidation of and affects the folding of INS protein]
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PPARG mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of RUNX2 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA; Allethrins inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; Allethrins inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; d,d-T80-prallethrin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; d,d-T80-prallethrin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; d,d-T80-prallethrin promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]; Pioglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; Pioglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; Pioglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]; Pioglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA]; quinoxyfen inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; quinoxyfen inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; Rosiglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; Rosiglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of RUNX2 mRNA]; Rosiglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; Rosiglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]; Rosiglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA]; Rosiglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PPARG mRNA]; tetrabromobisphenol A inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; tetrabromobisphenol A promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]; tetrabromobisphenol A promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA]; Tretinoin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; Tretinoin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA]; Tretinoin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PPARG mRNA]; Tretinoin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; triphenyltin hydroxide inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; triphenyltin hydroxide inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; triphenyltin hydroxide promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]; triphenyltin hydroxide promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA]
CTD PMID:23403016, PMID:25932594, PMID:32473317 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Insr insulin receptor multiple interactions EXP [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in increased expression of INSR mRNA] CTD PMID:21911000 NCBI chr12:1,682,527...1,816,414
Ensembl chr12:1,680,957...1,816,414
JBrowse link
G Ireb2 iron responsive element binding protein 2 multiple interactions ISO [Ascorbic Acid co-treated with CAT protein] inhibits the reaction [Zinc deficiency results in increased expression of IREB2 protein] CTD PMID:18073202 NCBI chr 8:59,450,974...59,503,634
Ensembl chr 8:59,420,123...59,501,118
JBrowse link
G Irs1 insulin receptor substrate 1 multiple interactions EXP [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of IRS1 protein]; [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in decreased phosphorylation of IRS1 protein] CTD PMID:21911000 NCBI chr 9:88,033,668...88,086,488
Ensembl chr 9:88,033,668...88,086,488
JBrowse link
G Isl1 ISL LIM homeobox 1 increases expression ISO Ascorbic Acid results in increased expression of ISL1 mRNA CTD PMID:15305145 NCBI chr 2:48,488,911...48,501,217
Ensembl chr 2:48,487,736...48,501,436
JBrowse link
G Jag1 jagged canonical Notch ligand 1 decreases expression ISO Ascorbic Acid results in decreased expression of JAG1 mRNA CTD PMID:15305145 NCBI chr 3:130,079,361...130,114,781
Ensembl chr 3:130,079,361...130,114,770
JBrowse link
G Kcnb1 potassium voltage-gated channel subfamily B member 1 multiple interactions ISO [Tretinoin co-treated with Ascorbic Acid] results in increased expression of KCNB1 mRNA CTD PMID:16443354 NCBI chr 3:163,850,785...163,935,610
Ensembl chr 3:163,850,785...163,935,617
JBrowse link
G Kdm3a lysine demethylase 3A multiple interactions ISO Ascorbic Acid inhibits the reaction [nickel chloride results in increased expression of KDM3A mRNA]; Ascorbic Acid inhibits the reaction [nickel chloride results in increased expression of KDM3A protein] CTD PMID:22318714 NCBI chr 4:99,503,160...99,547,315
Ensembl chr 4:99,503,176...99,546,905
JBrowse link
G Kdr kinase insert domain receptor decreases expression ISO Ascorbic Acid results in decreased expression of KDR mRNA CTD PMID:21919647 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 decreases expression
multiple interactions
ISO Ascorbic Acid results in decreased expression of KEAP1 protein
Ascorbic Acid inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of KEAP1 protein]
CTD PMID:31610155 NCBI chr 8:22,250,518...22,259,868
Ensembl chr 8:22,250,518...22,259,779
JBrowse link
G Kidins220 kinase D-interacting substrate 220 decreases expression EXP Ascorbic Acid results in decreased expression of KIDINS220 mRNA CTD PMID:15372504 NCBI chr 6:44,225,142...44,322,938
Ensembl chr 6:44,225,233...44,322,938
JBrowse link
G Kif1b kinesin family member 1B decreases expression EXP Ascorbic Acid results in decreased expression of KIF1B mRNA CTD PMID:15372504 NCBI chr 5:165,994,803...166,133,497
Ensembl chr 5:165,938,576...166,133,491
JBrowse link
G Kif1c kinesin family member 1C decreases expression EXP Ascorbic Acid results in decreased expression of KIF1C mRNA CTD PMID:15372504 NCBI chr10:57,322,259...57,352,395
Ensembl chr10:57,322,331...57,351,353
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G Kif23 kinesin family member 23 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in increased expression of KIF23 mRNA CTD PMID:17639512 NCBI chr 8:66,866,043...66,893,241
Ensembl chr 8:66,866,082...66,893,196
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G Klrk1 killer cell lectin like receptor K1 decreases expression ISO Ascorbic Acid deficiency results in decreased expression of KLRK1 protein CTD PMID:22306178 NCBI chr 4:163,392,652...163,403,735
Ensembl chr 4:163,393,217...163,403,653
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G Lck LCK pro