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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:gluconates
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Accession:CHEBI:33804 term browser browse the term


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chlorhexidine gluconate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpt glutamic--pyruvic transaminase increases secretion EXP chlorhexidine gluconate results in increased secretion of GPT protein CTD PMID:145039 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
sodium stibogluconate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions ISO [Lovastatin results in decreased activity of ABCC1 protein] which results in increased susceptibility to Antimony Sodium Gluconate CTD PMID:18056276 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Bcl6 BCL6, transcription repressor decreases expression ISO Antimony Sodium Gluconate results in decreased expression of BCL6 protein CTD PMID:27546522 NCBI chr11:80,255,790...80,279,075
Ensembl chr11:80,255,790...80,279,075
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression ISO Antimony Sodium Gluconate results in decreased expression of CCL2 mRNA CTD PMID:20102417 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Epo erythropoietin decreases expression ISO Antimony Sodium Gluconate results in decreased expression of EPO mRNA; Antimony Sodium Gluconate results in decreased expression of EPO protein CTD PMID:9531339 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G Icam1 intercellular adhesion molecule 1 affects response to substance ISO ICAM1 protein affects the susceptibility to Antimony Sodium Gluconate CTD PMID:11035738 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Ifng interferon gamma decreases expression
multiple interactions
affects response to substance
ISO Antimony Sodium Gluconate results in decreased expression of IFNG mRNA
[IFNG protein co-treated with Antimony Sodium Gluconate] results in decreased expression of IL10 mRNA; [IFNG protein co-treated with Antimony Sodium Gluconate] results in decreased expression of IL4 mRNA; [IFNG protein co-treated with Antimony Sodium Gluconate] results in increased expression of IL12B mRNA; [IFNG protein co-treated with Antimony Sodium Gluconate] results in increased expression of NOS2 mRNA; IFNG protein affects the reaction [IL10RA protein affects the susceptibility to Antimony Sodium Gluconate]
IFNG protein affects the susceptibility to Antimony Sodium Gluconate
[Antimony Sodium Gluconate co-treated with Amphotericin B] results in increased expression of IFNG protein
CTD PMID:9234779, PMID:9498473, PMID:10603400, PMID:12870129, PMID:17911647, PMID:20102417 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Ifngr1 interferon gamma receptor 1 increases expression ISO Antimony Sodium Gluconate results in increased expression of IFNGR1 mRNA; Antimony Sodium Gluconate results in increased expression of IFNGR1 protein CTD PMID:12803856 NCBI chr 1:15,062,380...15,080,815
Ensembl chr 1:15,062,432...15,080,907
JBrowse link
G Il10 interleukin 10 multiple interactions
decreases expression
affects response to substance
ISO [Antimony Sodium Gluconate co-treated with Amphotericin B] results in decreased expression of IL10 protein
Antimony Sodium Gluconate results in decreased expression of IL10 mRNA
IL10 protein affects the susceptibility to Antimony Sodium Gluconate
[IFNG protein co-treated with Antimony Sodium Gluconate] results in decreased expression of IL10 mRNA
CTD PMID:9234779, PMID:9498473, PMID:12379707, PMID:17911647, PMID:20102417 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il10ra interleukin 10 receptor subunit alpha multiple interactions
affects response to substance
ISO IFNG protein affects the reaction [IL10RA protein affects the susceptibility to Antimony Sodium Gluconate] CTD PMID:12379707, PMID:12870129 NCBI chr 8:49,558,062...49,573,891
Ensembl chr 8:49,560,035...49,573,742
JBrowse link
G Il12b interleukin 12B multiple interactions ISO [IFNG protein co-treated with Antimony Sodium Gluconate] results in increased expression of IL12B mRNA CTD PMID:9234779 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
JBrowse link
G Il1b interleukin 1 beta decreases expression ISO Antimony Sodium Gluconate results in decreased expression of IL1B mRNA CTD PMID:20102417 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il4 interleukin 4 decreases expression
multiple interactions
affects response to substance
ISO Antimony Sodium Gluconate results in decreased expression of IL4 mRNA
[IFNG protein co-treated with Antimony Sodium Gluconate] results in decreased expression of IL4 mRNA
IL4 protein affects the susceptibility to Antimony Sodium Gluconate
CTD PMID:7960131, PMID:9234779, PMID:11069076, PMID:20102417 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Itgam integrin subunit alpha M increases expression ISO Antimony Sodium Gluconate results in increased expression of ITGAM protein CTD PMID:12399974 NCBI chr 1:199,495,312...199,545,738
Ensembl chr 1:199,495,298...199,623,960
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO [IFNG protein co-treated with Antimony Sodium Gluconate] results in increased expression of NOS2 mRNA CTD PMID:9234779 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 decreases activity ISO Antimony Sodium Gluconate results in decreased activity of PTPN6 protein CTD PMID:12399974 NCBI chr 4:157,239,141...157,263,890
Ensembl chr 4:157,239,142...157,263,890
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO [Antimony Sodium Gluconate co-treated with Amphotericin B] results in decreased expression of TGFB1 protein CTD PMID:17911647 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tnf tumor necrosis factor decreases expression ISO Antimony Sodium Gluconate results in decreased expression of TNF mRNA CTD PMID:20102417 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf18 TNF receptor superfamily member 18 increases response to substance ISO TNFRSF18 protein results in increased susceptibility to Antimony Sodium Gluconate CTD PMID:20139272 NCBI chr 5:173,459,371...173,463,980
Ensembl chr 5:173,460,354...173,463,140
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A decreases expression ISO Antimony Sodium Gluconate results in decreased expression of TNFRSF1A protein CTD PMID:7844400 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B decreases expression ISO Antimony Sodium Gluconate results in decreased expression of TNFRSF1B protein CTD PMID:7844400 NCBI chr 5:163,136,390...163,167,299
Ensembl chr 5:163,136,390...163,167,299
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    chemical entity 19787
      molecular entity 19784
        ion 15918
          anion 14924
            organic anion 3012
              carboxylic acid anion 2386
                carbohydrate acid anion 21
                  aldonate 21
                    hexonate 21
                      gluconates 21
                        D-gluconate adduct + 21
                        gluconate + 0
                        ketogluconate + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19574
                        carbon atom 19563
                          organic molecular entity 19563
                            organic ion 8320
                              organic anion 3012
                                carboxylic acid anion 2386
                                  carbohydrate acid anion 21
                                    aldonate 21
                                      hexonate 21
                                        gluconates 21
                                          D-gluconate adduct + 21
                                          gluconate + 0
                                          ketogluconate + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.