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ONTOLOGY REPORT - ANNOTATIONS


Term:heteroarene
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Accession:CHEBI:33833 term browser browse the term
Definition:A heterocyclic compound formally derived from an arene by replacement of one or more methine (-C=) and/or vinylene (-CH=CH-) groups by trivalent or divalent heteroatoms, respectively, in such a way as to maintain the continuous pi-electron system characteristic of aromatic systems and a number of out-of-plane pi-electrons corresponding to the Hueckel rule (4n+2).
Synonyms:exact_synonym: heteroarenes
 related_synonym: hetarenes


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3',5'-cyclic AMP term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G P2RY2 purinergic receptor P2Y2 JBrowse link 21 24,987,568 25,009,754 RGD:6480464
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Symbol Object Name JBrowse Chr Start Stop Reference
G CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase JBrowse link 6 17,910,141 17,914,573 RGD:6480464
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Symbol Object Name JBrowse Chr Start Stop Reference
G CFTR CF transmembrane conductance regulator JBrowse link 14 56,290,417 56,452,919 RGD:6480464
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Symbol Object Name JBrowse Chr Start Stop Reference
G SLC2A9 solute carrier family 2 member 9 JBrowse link 3 69,394,304 69,588,462 RGD:6480464
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Symbol Object Name JBrowse Chr Start Stop Reference
G CFTR CF transmembrane conductance regulator JBrowse link 14 56,290,417 56,452,919 RGD:6480464
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Symbol Object Name JBrowse Chr Start Stop Reference
G AVP arginine vasopressin JBrowse link 24 18,183,057 18,184,827 RGD:6480464
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Symbol Object Name JBrowse Chr Start Stop Reference
G PTGS1 prostaglandin-endoperoxide synthase 1 JBrowse link 9 60,195,118 60,216,847 RGD:6480464
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G MYC MYC proto-oncogene, bHLH transcription factor JBrowse link 13 25,200,772 25,205,309 RGD:6480464
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Symbol Object Name JBrowse Chr Start Stop Reference
G NR1I2 nuclear receptor subfamily 1 group I member 2 JBrowse link 33 23,444,367 23,456,405 RGD:6480464
G NR1I3 nuclear receptor subfamily 1 group I member 3 JBrowse link 38 21,252,874 21,257,951 RGD:6480464
cytidine 5'-monophosphate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase JBrowse link 6 17,910,141 17,914,573 RGD:6480464
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Symbol Object Name JBrowse Chr Start Stop Reference
G NISCH nischarin JBrowse link 20 37,278,660 37,312,549 RGD:6480464
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Symbol Object Name JBrowse Chr Start Stop Reference
G SELP selectin P JBrowse link 7 28,956,428 28,997,266 RGD:6480464
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Symbol Object Name JBrowse Chr Start Stop Reference
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 JBrowse link 28 41,079,164 41,089,188 RGD:6480464
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Symbol Object Name JBrowse Chr Start Stop Reference
G NR1I3 nuclear receptor subfamily 1 group I member 3 JBrowse link 38 21,252,874 21,257,951 RGD:6480464
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Symbol Object Name JBrowse Chr Start Stop Reference
G HEXB hexosaminidase subunit beta JBrowse link 2 57,221,809 57,248,432 RGD:6480464
G PTGS1 prostaglandin-endoperoxide synthase 1 JBrowse link 9 60,195,118 60,216,847 RGD:6480464
iprodione term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AHR aryl hydrocarbon receptor JBrowse link 14 31,743,704 31,793,484 RGD:6480464
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 JBrowse link 30 37,793,277 37,799,535 RGD:6480464
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Symbol Object Name JBrowse Chr Start Stop Reference
G DHRS4 dehydrogenase/reductase 4 JBrowse link 8 4,046,532 4,058,498 RGD:6480464
ketoconazole term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABCB1 ATP binding cassette subfamily B member 1 JBrowse link 14 13,644,891 13,852,829 RGD:6480464
G CYP3A12 cytochrome P-450 3A12 RGD:6480464
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Symbol Object Name JBrowse Chr Start Stop Reference
G REN renin JBrowse link 38 744,540 766,998 RGD:6480464
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Symbol Object Name JBrowse Chr Start Stop Reference
G REN renin JBrowse link 38 744,540 766,998 RGD:6480464
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Symbol Object Name JBrowse Chr Start Stop Reference
G REN renin JBrowse link 38 744,540 766,998 RGD:6480464
prochloraz term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AHR aryl hydrocarbon receptor JBrowse link 14 31,743,704 31,793,484 RGD:6480464
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 JBrowse link 30 37,793,277 37,799,535 RGD:6480464
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Symbol Object Name JBrowse Chr Start Stop Reference
G HEXB hexosaminidase subunit beta JBrowse link 2 57,221,809 57,248,432 RGD:6480464
ritonavir term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABCB1 ATP binding cassette subfamily B member 1 JBrowse link 14 13,644,891 13,852,829 RGD:6480464
G NR1I2 nuclear receptor subfamily 1 group I member 2 JBrowse link 33 23,444,367 23,456,405 RGD:6480464
serotonin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AGT angiotensinogen JBrowse link 4 8,681,192 8,694,059 RGD:6480464
G EDN1 endothelin 1 JBrowse link 35 11,808,892 11,815,383 RGD:6480464
silodosin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADRA1A adrenoceptor alpha 1A JBrowse link 25 30,690,959 30,801,484 RGD:6480464
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Symbol Object Name JBrowse Chr Start Stop Reference
G NR1I3 nuclear receptor subfamily 1 group I member 3 JBrowse link 38 21,252,874 21,257,951 RGD:6480464
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Symbol Object Name JBrowse Chr Start Stop Reference
G HSP90B1 heat shock protein 90 beta family member 1 JBrowse link 15 42,456,793 42,474,122 RGD:6480464
G HSPA5 heat shock protein family A (Hsp70) member 5 JBrowse link 9 57,850,870 57,855,607 RGD:6480464
UTP term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G P2RY2 purinergic receptor P2Y2 JBrowse link 21 24,987,568 25,009,754 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 223
    chemical entity 223
      molecular entity 223
        polyatomic entity 215
          molecule 200
            cyclic compound 182
              organic cyclic compound 182
                organic heterocyclic compound 141
                  heteroarene 24
                    (-)-Ngaione 0
                    (5-phenyl-3-isoxazolyl)-(1-pyrrolidinyl)methanone 0
                    1-(3-hydroxy-2,4,4-trimethyl-1-oxido-5-thiophen-2-yl-2-imidazol-1-iumyl)ethanone 0
                    1-(6-methyl-2-pyridinyl)-N-(3-pyridinyl)-4-imidazolecarboxamide 0
                    1-adamantanecarboxylic acid [2-(2-furanylmethylamino)-2-oxoethyl] ester 0
                    1-azocanyl-[(2R,4R)-2-(4-hydroxybutoxy)-4-thiophen-2-yl-3,4-dihydro-2H-pyran-6-yl]methanone 0
                    2-(2-furanyl)-6,7,8,9-tetrahydro-5H-cyclohepta[2,3]thieno[2,4-b][1,3]oxazin-4-one 0
                    2-[(2R,4aR,12aR)-5-methyl-8-[[(5-methyl-3-isoxazolyl)-oxomethyl]amino]-6-oxo-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-2-yl]acetic acid 0
                    2-amino-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d][1,3]thiazin-4-one 0
                    2-furanyl-(4,4,8-trimethyl-1-sulfanylidene-5-dithiolo[3,4-c]quinolinyl)methanone 0
                    2-sulfanylidene-1,3-dithiole-4,5-dicarboxylic acid dimethyl ester 0
                    4,6-dioxo-1H-1,3,5-triazine-2-carboxamide 0
                    4-(2-furanylmethylidene)-2-methyl-5-oxo-1-prop-2-enyl-3-pyrrolecarboxylic acid methyl ester 0
                    4-[(E)-[hydroxymethyl(methyl)amino]diazenyl]-1H-imidazole-5-carboxamide 0
                    4-[2-(2-chloro-4-fluoroanilino)-5-methyl-4-pyrimidinyl]-N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-1H-pyrrole-2-carboxamide 0
                    4-[oxo-(pyridin-4-ylamino)methyl]-1H-imidazole-5-carboxylic acid ethyl ester 0
                    4-acetyl-N-[4-(4-chlorophenyl)-2-thiazolyl]-3,5-dimethyl-1H-pyrrole-2-carboxamide 0
                    4-bromo-1-methyl-N-(2-thiazolyl)-3-pyrazolecarboxamide 0
                    4-chloro-1-methyl-N-[1-[(4-methylphenyl)methyl]-3-pyrazolyl]-3-pyrazolecarboxamide 0
                    4-chloro-N-[(4-chlorophenyl)methyl]-3-nitro-1H-pyrazole-5-carboxamide 0
                    5-(2-furanyl)-N-(3-pyridinylmethyl)-3-isoxazolecarboxamide 0
                    5-(2-methylphenyl)-N-(phenylmethyl)-2-furancarboxamide 0
                    5-(3-chlorophenyl)-N-(2-propyl-5-tetrazolyl)-2-furancarboxamide 0
                    5-(3-hydroxyphenyl)-N-[2-(4-morpholinyl)ethyl]-3-isoxazolecarboxamide 0
                    5-(4-bromophenyl)-N,N-diethyl-3-isoxazolecarboxamide 0
                    5-(4-bromophenyl)-N-propan-2-yl-3-isoxazolecarboxamide 0
                    5-(4-chlorophenyl)-N-(2-furanylmethyl)-3-isoxazolecarboxamide 0
                    5-(4-chlorophenyl)-N-(5-ethyl-1,3,4-thiadiazol-2-yl)-2-furancarboxamide 0
                    5-(4-methylphenyl)-N-(3-pyridinylmethyl)-3-isoxazolecarboxamide 0
                    5-[(4-fluorophenyl)methylsulfonylmethyl]-N-(2-oxolanylmethyl)-2-furancarboxamide 0
                    5-bromo-N-[1-(2,5-dimethylphenyl)ethyl]-2-furancarboxamide 0
                    5-bromo-N-[2-(4-fluorophenyl)-2-(4-morpholinyl)ethyl]-2-furancarboxamide 0
                    5-bromo-N-[6-[[(5-bromo-2-furanyl)-oxomethyl]amino]-2-pyridinyl]-2-furancarboxamide 0
                    5-methyl-N-(3-pyridinyl)-3-isoxazolecarboxamide 0
                    5-methyl-N-(5-methyl-3-isoxazolyl)-3-isoxazolecarboxamide 0
                    5-methyl-N-[4-(2-pyridinyl)-2-thiazolyl]-2-furancarboxamide 0
                    5-methyl-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]-3-isoxazolecarboxamide 0
                    5-phenyl-N-(3-pyridinyl)-3-isoxazolecarboxamide 0
                    N,N-dicyclohexyl-5-propyl-3-isoxazolecarboxamide 0
                    N-(2-adamantyl)-4-bromo-1-methyl-3-pyrazolecarboxamide 0
                    N-(2-cyano-1-cyclopentenyl)-1-ethyl-3-pyrazolecarboxamide 0
                    N-(2-sulfanylidene-3H-1,3,4-thiadiazol-5-yl)-2-furancarboxamide 0
                    N-(3,3,5-trimethylcyclohexyl)-1H-1,2,4-triazole-5-carboxamide 0
                    N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-5-(2-methylpropyl)-3-isoxazolecarboxamide 0
                    N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-5-methyl-4-nitro-3-isoxazolecarboxamide 0
                    N-(3-cyano-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl)-5-cyclopropyl-3-isoxazolecarboxamide 0
                    N-(3-cyano-6-methyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-5-methyl-3-isoxazolecarboxamide 0
                    N-(3-pyridinyl)-5,6,7,8-tetrahydro-4H-cyclohepta[d]isoxazole-3-carboxamide 0
                    N-(4-cyano-2-methyl-3-pyrazolyl)-5-(4-methylphenyl)-3-isoxazolecarboxamide 0
                    N-(4-oxo-2-thieno[3,2-d][1,3]thiazinyl)-2-furancarboxamide 0
                    N-(5-chloro-2-pyridinyl)-2-ethyl-3-pyrazolecarboxamide 0
                    N-(5-cyclohexyl-1,3,4-thiadiazol-2-yl)-2-furancarboxamide 0
                    N-(6-tert-butyl-3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-5-cyclopropyl-3-isoxazolecarboxamide 0
                    N-[(2R,3R)-2-[(dimethylamino)methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]-2,5-dimethyl-3-pyrazolecarboxamide 0
                    N-[(2R,3R)-2-[(dimethylamino)methyl]-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]-2,5-dimethyl-3-pyrazolecarboxamide 0
                    N-[(2R,3R)-2-[[[(cyclohexylamino)-oxomethyl]-methylamino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]-2,5-dimethyl-3-pyrazolecarboxamide 0
                    N-[(2R,3S)-2-[(dimethylamino)methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]-2,5-dimethyl-3-pyrazolecarboxamide 0
                    N-[(2R,3S)-2-[[[(cyclohexylamino)-oxomethyl]-methylamino]methyl]-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]-2,5-dimethyl-3-pyrazolecarboxamide 0
                    N-[(2R,4aR,12aR)-2-[2-(cyclopentylamino)-2-oxoethyl]-5-methyl-6-oxo-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-8-yl]-5-methyl-1,2-oxazole-3-carboxamide 0
                    N-[(2R,4aR,12aR)-2-[2-(ethylamino)-2-oxoethyl]-5-methyl-6-oxo-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-8-yl]-5-methyl-3-isoxazolecarboxamide 0
                    N-[(2R,4aR,12aR)-5-methyl-6-oxo-2-[2-oxo-2-(propylamino)ethyl]-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-8-yl]-5-methyl-3-isoxazolecarboxamide 0
                    N-[(2R,4aR,12aR)-5-methyl-6-oxo-2-[2-oxo-2-[[(1R)-1-phenylethyl]amino]ethyl]-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-8-yl]-5-methyl-3-isoxazolecarboxamide 0
                    N-[(2R,4aR,12aS)-2-[2-(cyclopentylamino)-2-oxoethyl]-5-methyl-6-oxo-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-8-yl]-5-methyl-1,2-oxazole-3-carboxamide 0
                    N-[(2R,4aS,12aR)-2-[2-(cyclopentylamino)-2-oxoethyl]-5-methyl-6-oxo-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-8-yl]-5-methyl-3-isoxazolecarboxamide 0
                    N-[(2S,3R)-2-[(dimethylamino)methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]-2,5-dimethyl-3-pyrazolecarboxamide 0
                    N-[(2S,3R)-2-[[[(cyclohexylamino)-oxomethyl]-methylamino]methyl]-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]-2,5-dimethyl-3-pyrazolecarboxamide 0
                    N-[(2S,3S)-2-[(dimethylamino)methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]-2,5-dimethyl-3-pyrazolecarboxamide 0
                    N-[(2S,3S)-2-[[[(cyclohexylamino)-oxomethyl]-methylamino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]-2,5-dimethyl-3-pyrazolecarboxamide 0
                    N-[(2S,3S)-2-[[[(cyclohexylamino)-oxomethyl]-methylamino]methyl]-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]-2,5-dimethyl-3-pyrazolecarboxamide 0
                    N-[(2S,4aR,12aR)-2-[2-(cyclopentylamino)-2-oxoethyl]-5-methyl-6-oxo-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-8-yl]-5-methyl-3-isoxazolecarboxamide 0
                    N-[(2S,4aR,12aS)-2-[2-(cyclopentylamino)-2-oxoethyl]-5-methyl-6-oxo-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-8-yl]-5-methyl-3-isoxazolecarboxamide 0
                    N-[(2S,4aS,12aR)-2-[2-(cyclopentylamino)-2-oxoethyl]-5-methyl-6-oxo-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-8-yl]-5-methyl-3-isoxazolecarboxamide 0
                    N-[(2S,4aS,12aS)-2-[2-(cyclopentylamino)-2-oxoethyl]-5-methyl-6-oxo-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-8-yl]-5-methyl-3-isoxazolecarboxamide 0
                    N-[1-(2-furanyl)ethylideneamino]carbamic acid tert-butyl ester 0
                    N-[1-[(4-fluorophenyl)methyl]-3,5-dimethyl-4-pyrazolyl]-5-(2-furanyl)-3-isoxazolecarboxamide 0
                    N-[1-[(4-fluorophenyl)methyl]-3-pyrazolyl]-5-methyl-2-furancarboxamide 0
                    N-[1-[(4-fluorophenyl)methyl]-4-pyrazolyl]-5-(2-furanyl)-3-isoxazolecarboxamide 0
                    N-[2-(1-cyclohexenyl)ethyl]-5-methyl-3-isoxazolecarboxamide 0
                    N-[4-(3,4-dimethylphenyl)-2-thiazolyl]-2-furancarboxamide 0
                    N-[4-(4-chlorophenyl)-2-thiazolyl]-N-[3-(diethylamino)propyl]-2-furancarboxamide 0
                    N-cyclohexyl-5,6,7,8-tetrahydro-4H-cyclohepta[d]isoxazole-3-carboxamide 0
                    N-cyclohexyl-5-propyl-3-isoxazolecarboxamide 0
                    N-cyclopropyl-5-thiophen-2-yl-3-isoxazolecarboxamide 0
                    [4-[1-(1-cyclopentyl-5-tetrazolyl)propyl]-1-piperazinyl]-(2-furanyl)methanone 0
                    azaarene + 0
                    ethylmethylthiambutene 0
                    heteroaryl group + 0
                    hydracarbazine 0
                    imidazopyrimidine + 4
                    monocyclic heteroarene + 12
                    nucleobase-containing molecular entity + 5
                    penthienate 0
                    polycyclic heteroarene + 7
                    pteridines + 0
                    rufinamide 0
                    tetrapyrrole + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 223
    subatomic particle 223
      composite particle 223
        hadron 223
          baryon 223
            nucleon 223
              atomic nucleus 223
                atom 223
                  main group element atom 216
                    p-block element atom 216
                      carbon group element atom 205
                        carbon atom 204
                          organic molecular entity 204
                            organic molecule 198
                              organic cyclic compound 182
                                organic heterocyclic compound 141
                                  heteroarene 24
                                    (-)-Ngaione 0
                                    (5-phenyl-3-isoxazolyl)-(1-pyrrolidinyl)methanone 0
                                    1-(3-hydroxy-2,4,4-trimethyl-1-oxido-5-thiophen-2-yl-2-imidazol-1-iumyl)ethanone 0
                                    1-(6-methyl-2-pyridinyl)-N-(3-pyridinyl)-4-imidazolecarboxamide 0
                                    1-adamantanecarboxylic acid [2-(2-furanylmethylamino)-2-oxoethyl] ester 0
                                    1-azocanyl-[(2R,4R)-2-(4-hydroxybutoxy)-4-thiophen-2-yl-3,4-dihydro-2H-pyran-6-yl]methanone 0
                                    2-(2-furanyl)-6,7,8,9-tetrahydro-5H-cyclohepta[2,3]thieno[2,4-b][1,3]oxazin-4-one 0
                                    2-[(2R,4aR,12aR)-5-methyl-8-[[(5-methyl-3-isoxazolyl)-oxomethyl]amino]-6-oxo-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-2-yl]acetic acid 0
                                    2-amino-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d][1,3]thiazin-4-one 0
                                    2-furanyl-(4,4,8-trimethyl-1-sulfanylidene-5-dithiolo[3,4-c]quinolinyl)methanone 0
                                    2-sulfanylidene-1,3-dithiole-4,5-dicarboxylic acid dimethyl ester 0
                                    4,6-dioxo-1H-1,3,5-triazine-2-carboxamide 0
                                    4-(2-furanylmethylidene)-2-methyl-5-oxo-1-prop-2-enyl-3-pyrrolecarboxylic acid methyl ester 0
                                    4-[(E)-[hydroxymethyl(methyl)amino]diazenyl]-1H-imidazole-5-carboxamide 0
                                    4-[2-(2-chloro-4-fluoroanilino)-5-methyl-4-pyrimidinyl]-N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-1H-pyrrole-2-carboxamide 0
                                    4-[oxo-(pyridin-4-ylamino)methyl]-1H-imidazole-5-carboxylic acid ethyl ester 0
                                    4-acetyl-N-[4-(4-chlorophenyl)-2-thiazolyl]-3,5-dimethyl-1H-pyrrole-2-carboxamide 0
                                    4-bromo-1-methyl-N-(2-thiazolyl)-3-pyrazolecarboxamide 0
                                    4-chloro-1-methyl-N-[1-[(4-methylphenyl)methyl]-3-pyrazolyl]-3-pyrazolecarboxamide 0
                                    4-chloro-N-[(4-chlorophenyl)methyl]-3-nitro-1H-pyrazole-5-carboxamide 0
                                    5-(2-furanyl)-N-(3-pyridinylmethyl)-3-isoxazolecarboxamide 0
                                    5-(2-methylphenyl)-N-(phenylmethyl)-2-furancarboxamide 0
                                    5-(3-chlorophenyl)-N-(2-propyl-5-tetrazolyl)-2-furancarboxamide 0
                                    5-(3-hydroxyphenyl)-N-[2-(4-morpholinyl)ethyl]-3-isoxazolecarboxamide 0
                                    5-(4-bromophenyl)-N,N-diethyl-3-isoxazolecarboxamide 0
                                    5-(4-bromophenyl)-N-propan-2-yl-3-isoxazolecarboxamide 0
                                    5-(4-chlorophenyl)-N-(2-furanylmethyl)-3-isoxazolecarboxamide 0
                                    5-(4-chlorophenyl)-N-(5-ethyl-1,3,4-thiadiazol-2-yl)-2-furancarboxamide 0
                                    5-(4-methylphenyl)-N-(3-pyridinylmethyl)-3-isoxazolecarboxamide 0
                                    5-[(4-fluorophenyl)methylsulfonylmethyl]-N-(2-oxolanylmethyl)-2-furancarboxamide 0
                                    5-bromo-N-[1-(2,5-dimethylphenyl)ethyl]-2-furancarboxamide 0
                                    5-bromo-N-[2-(4-fluorophenyl)-2-(4-morpholinyl)ethyl]-2-furancarboxamide 0
                                    5-bromo-N-[6-[[(5-bromo-2-furanyl)-oxomethyl]amino]-2-pyridinyl]-2-furancarboxamide 0
                                    5-methyl-N-(3-pyridinyl)-3-isoxazolecarboxamide 0
                                    5-methyl-N-(5-methyl-3-isoxazolyl)-3-isoxazolecarboxamide 0
                                    5-methyl-N-[4-(2-pyridinyl)-2-thiazolyl]-2-furancarboxamide 0
                                    5-methyl-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]-3-isoxazolecarboxamide 0
                                    5-phenyl-N-(3-pyridinyl)-3-isoxazolecarboxamide 0
                                    N,N-dicyclohexyl-5-propyl-3-isoxazolecarboxamide 0
                                    N-(2-adamantyl)-4-bromo-1-methyl-3-pyrazolecarboxamide 0
                                    N-(2-cyano-1-cyclopentenyl)-1-ethyl-3-pyrazolecarboxamide 0
                                    N-(2-sulfanylidene-3H-1,3,4-thiadiazol-5-yl)-2-furancarboxamide 0
                                    N-(3,3,5-trimethylcyclohexyl)-1H-1,2,4-triazole-5-carboxamide 0
                                    N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-5-(2-methylpropyl)-3-isoxazolecarboxamide 0
                                    N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-5-methyl-4-nitro-3-isoxazolecarboxamide 0
                                    N-(3-cyano-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl)-5-cyclopropyl-3-isoxazolecarboxamide 0
                                    N-(3-cyano-6-methyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-5-methyl-3-isoxazolecarboxamide 0
                                    N-(3-pyridinyl)-5,6,7,8-tetrahydro-4H-cyclohepta[d]isoxazole-3-carboxamide 0
                                    N-(4-cyano-2-methyl-3-pyrazolyl)-5-(4-methylphenyl)-3-isoxazolecarboxamide 0
                                    N-(4-oxo-2-thieno[3,2-d][1,3]thiazinyl)-2-furancarboxamide 0
                                    N-(5-chloro-2-pyridinyl)-2-ethyl-3-pyrazolecarboxamide 0
                                    N-(5-cyclohexyl-1,3,4-thiadiazol-2-yl)-2-furancarboxamide 0
                                    N-(6-tert-butyl-3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-5-cyclopropyl-3-isoxazolecarboxamide 0
                                    N-[(2R,3R)-2-[(dimethylamino)methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]-2,5-dimethyl-3-pyrazolecarboxamide 0
                                    N-[(2R,3R)-2-[(dimethylamino)methyl]-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]-2,5-dimethyl-3-pyrazolecarboxamide 0
                                    N-[(2R,3R)-2-[[[(cyclohexylamino)-oxomethyl]-methylamino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]-2,5-dimethyl-3-pyrazolecarboxamide 0
                                    N-[(2R,3S)-2-[(dimethylamino)methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]-2,5-dimethyl-3-pyrazolecarboxamide 0
                                    N-[(2R,3S)-2-[[[(cyclohexylamino)-oxomethyl]-methylamino]methyl]-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]-2,5-dimethyl-3-pyrazolecarboxamide 0
                                    N-[(2R,4aR,12aR)-2-[2-(cyclopentylamino)-2-oxoethyl]-5-methyl-6-oxo-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-8-yl]-5-methyl-1,2-oxazole-3-carboxamide 0
                                    N-[(2R,4aR,12aR)-2-[2-(ethylamino)-2-oxoethyl]-5-methyl-6-oxo-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-8-yl]-5-methyl-3-isoxazolecarboxamide 0
                                    N-[(2R,4aR,12aR)-5-methyl-6-oxo-2-[2-oxo-2-(propylamino)ethyl]-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-8-yl]-5-methyl-3-isoxazolecarboxamide 0
                                    N-[(2R,4aR,12aR)-5-methyl-6-oxo-2-[2-oxo-2-[[(1R)-1-phenylethyl]amino]ethyl]-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-8-yl]-5-methyl-3-isoxazolecarboxamide 0
                                    N-[(2R,4aR,12aS)-2-[2-(cyclopentylamino)-2-oxoethyl]-5-methyl-6-oxo-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-8-yl]-5-methyl-1,2-oxazole-3-carboxamide 0
                                    N-[(2R,4aS,12aR)-2-[2-(cyclopentylamino)-2-oxoethyl]-5-methyl-6-oxo-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-8-yl]-5-methyl-3-isoxazolecarboxamide 0
                                    N-[(2S,3R)-2-[(dimethylamino)methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]-2,5-dimethyl-3-pyrazolecarboxamide 0
                                    N-[(2S,3R)-2-[[[(cyclohexylamino)-oxomethyl]-methylamino]methyl]-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]-2,5-dimethyl-3-pyrazolecarboxamide 0
                                    N-[(2S,3S)-2-[(dimethylamino)methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]-2,5-dimethyl-3-pyrazolecarboxamide 0
                                    N-[(2S,3S)-2-[[[(cyclohexylamino)-oxomethyl]-methylamino]methyl]-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]-2,5-dimethyl-3-pyrazolecarboxamide 0
                                    N-[(2S,3S)-2-[[[(cyclohexylamino)-oxomethyl]-methylamino]methyl]-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-10-yl]-2,5-dimethyl-3-pyrazolecarboxamide 0
                                    N-[(2S,4aR,12aR)-2-[2-(cyclopentylamino)-2-oxoethyl]-5-methyl-6-oxo-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-8-yl]-5-methyl-3-isoxazolecarboxamide 0
                                    N-[(2S,4aR,12aS)-2-[2-(cyclopentylamino)-2-oxoethyl]-5-methyl-6-oxo-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-8-yl]-5-methyl-3-isoxazolecarboxamide 0
                                    N-[(2S,4aS,12aR)-2-[2-(cyclopentylamino)-2-oxoethyl]-5-methyl-6-oxo-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-8-yl]-5-methyl-3-isoxazolecarboxamide 0
                                    N-[(2S,4aS,12aS)-2-[2-(cyclopentylamino)-2-oxoethyl]-5-methyl-6-oxo-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-8-yl]-5-methyl-3-isoxazolecarboxamide 0
                                    N-[1-(2-furanyl)ethylideneamino]carbamic acid tert-butyl ester 0
                                    N-[1-[(4-fluorophenyl)methyl]-3,5-dimethyl-4-pyrazolyl]-5-(2-furanyl)-3-isoxazolecarboxamide 0
                                    N-[1-[(4-fluorophenyl)methyl]-3-pyrazolyl]-5-methyl-2-furancarboxamide 0
                                    N-[1-[(4-fluorophenyl)methyl]-4-pyrazolyl]-5-(2-furanyl)-3-isoxazolecarboxamide 0
                                    N-[2-(1-cyclohexenyl)ethyl]-5-methyl-3-isoxazolecarboxamide 0
                                    N-[4-(3,4-dimethylphenyl)-2-thiazolyl]-2-furancarboxamide 0
                                    N-[4-(4-chlorophenyl)-2-thiazolyl]-N-[3-(diethylamino)propyl]-2-furancarboxamide 0
                                    N-cyclohexyl-5,6,7,8-tetrahydro-4H-cyclohepta[d]isoxazole-3-carboxamide 0
                                    N-cyclohexyl-5-propyl-3-isoxazolecarboxamide 0
                                    N-cyclopropyl-5-thiophen-2-yl-3-isoxazolecarboxamide 0
                                    [4-[1-(1-cyclopentyl-5-tetrazolyl)propyl]-1-piperazinyl]-(2-furanyl)methanone 0
                                    azaarene + 0
                                    ethylmethylthiambutene 0
                                    heteroaryl group + 0
                                    hydracarbazine 0
                                    imidazopyrimidine + 4
                                    monocyclic heteroarene + 12
                                    nucleobase-containing molecular entity + 5
                                    penthienate 0
                                    polycyclic heteroarene + 7
                                    pteridines + 0
                                    rufinamide 0
                                    tetrapyrrole + 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.