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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:arenecarbaldehyde
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Accession:CHEBI:33855 term browser browse the term
Definition:Any aldehyde in which the carbonyl group is attached to an aromatic moiety.
Synonyms:related_synonym: Aromatic aldehyde;   Formula=CHOR;   SMILES=*C(=O)[H];   an aromatic aldehyde;   arenecarbaldehydes;   aryl aldehyde;   aryl aldehydes
 alt_id: CHEBI:13819;   CHEBI:22621;   CHEBI:2832;   CHEBI:87908
 xref: KEGG:C00193;   MetaCyc:Aryl-Aldehyde


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1-naphthaldehyde term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions EXP 1-naphthaldehyde inhibits the reaction [Metribolone binds to AR protein] CTD PMID:3695475 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
2,5-dihydroxybenzaldehyde term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh2 aldehyde dehydrogenase 2 family member increases metabolic processing ISO ALDH2 protein results in increased metabolism of 2,5-dihydroxybenzaldehyde CTD PMID:11744614 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
2-nitrobenzaldehyde term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr7a2 aldo-keto reductase family 7, member A2 increases reduction
affects reduction
ISO AKR7A2 protein results in increased reduction of 2-nitrobenzaldehyde
2-nitrobenzaldehyde affects the reduction of AKR7A5 protein
CTD PMID:10510318, PMID:12604212 NCBI chr 5:157,759,448...157,768,473
Ensembl chr 5:157,759,416...157,768,471
JBrowse link
3,4-dihydroxybenzaldehyde term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions ISO protocatechualdehyde inhibits the reaction [Potassium Dichromate results in decreased activity of ACHE protein]; protocatechualdehyde inhibits the reaction [sodium arsenite results in decreased activity of ACHE protein] CTD PMID:29665407, PMID:29732668 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions EXP protocatechualdehyde inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein] CTD PMID:25582705 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Ager advanced glycosylation end product-specific receptor multiple interactions ISO
EXP
protocatechualdehyde inhibits the reaction [S100B protein results in increased expression of AGER mRNA]; protocatechualdehyde inhibits the reaction [S100B protein results in increased expression of AGER protein]; protocatechualdehyde inhibits the reaction [TGFB1 protein results in decreased expression of AGER protein]
protocatechualdehyde inhibits the reaction [Bleomycin results in decreased expression of AGER protein]
CTD PMID:17597607, PMID:25582705 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Cat catalase multiple interactions
increases activity
ISO protocatechualdehyde inhibits the reaction [Potassium Dichromate results in decreased activity of CAT protein]; protocatechualdehyde inhibits the reaction [sodium arsenite results in decreased activity of CAT protein]
protocatechualdehyde results in increased activity of CAT protein
CTD PMID:29665407, PMID:29732668 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cdh1 cadherin 1 multiple interactions ISO protocatechualdehyde inhibits the reaction [TGFB1 protein results in decreased expression of CDH1 protein] CTD PMID:25582705 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Fgf2 fibroblast growth factor 2 multiple interactions ISO
EXP
protocatechualdehyde inhibits the reaction [TGFB1 protein results in increased expression of FGF2 protein]
protocatechualdehyde inhibits the reaction [Bleomycin results in increased expression of FGF2 protein]
CTD PMID:25582705 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase multiple interactions ISO protocatechualdehyde inhibits the reaction [Potassium Dichromate results in decreased activity of G6PD protein]; protocatechualdehyde inhibits the reaction [sodium arsenite results in decreased activity of G6PD protein] CTD PMID:29665407, PMID:29732668 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Glo1 glyoxalase 1 multiple interactions ISO protocatechualdehyde inhibits the reaction [sodium arsenite results in increased activity of GLO1 protein] CTD PMID:29732668 NCBI chr20:9,273,589...9,291,608
Ensembl chr20:9,273,594...9,291,610
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions ISO protocatechualdehyde inhibits the reaction [Potassium Dichromate results in decreased activity of GSR protein]; protocatechualdehyde inhibits the reaction [sodium arsenite results in decreased activity of GSR protein] CTD PMID:29665407, PMID:29732668 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions EXP
ISO
protocatechualdehyde inhibits the reaction [Bleomycin results in increased expression of HMGB1 protein]
protocatechualdehyde inhibits the reaction [TGFB1 protein results in increased expression of HMGB1 protein]
CTD PMID:25582705 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G S100b S100 calcium binding protein B multiple interactions ISO protocatechualdehyde inhibits the reaction [S100B protein results in increased expression of AGER mRNA]; protocatechualdehyde inhibits the reaction [S100B protein results in increased expression of AGER protein]; protocatechualdehyde inhibits the reaction [S100B protein results in increased expression of TGFB1 mRNA]; protocatechualdehyde inhibits the reaction [S100B protein results in increased expression of TGFB1 protein]; protocatechualdehyde inhibits the reaction [S100B protein results in increased phosphorylation of and affects the localization of SMAD2 protein]; protocatechualdehyde inhibits the reaction [S100B protein results in increased phosphorylation of and affects the localization of SMAD3 protein] CTD PMID:17597607 NCBI chr20:13,130,633...13,142,856
Ensembl chr20:13,130,636...13,142,856
JBrowse link
G Smad2 SMAD family member 2 multiple interactions ISO protocatechualdehyde inhibits the reaction [Glucose results in increased phosphorylation of and affects the localization of SMAD2 protein]; protocatechualdehyde inhibits the reaction [S100B protein results in increased phosphorylation of and affects the localization of SMAD2 protein] CTD PMID:17597607 NCBI chr18:72,550,107...72,612,078
Ensembl chr18:72,550,219...72,612,078
JBrowse link
G Smad3 SMAD family member 3 multiple interactions ISO protocatechualdehyde inhibits the reaction [Glucose results in increased phosphorylation of and affects the localization of SMAD3 protein]; protocatechualdehyde inhibits the reaction [S100B protein results in increased phosphorylation of and affects the localization of SMAD3 protein] CTD PMID:17597607 NCBI chr 8:68,569,530...68,678,349
Ensembl chr 8:68,569,530...68,678,349
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO protocatechualdehyde inhibits the reaction [Potassium Dichromate results in increased activity of SOD1 protein]; protocatechualdehyde inhibits the reaction [sodium arsenite results in decreased activity of SOD1 protein] CTD PMID:29665407, PMID:29732668 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO protocatechualdehyde inhibits the reaction [Glucose results in increased expression of TGFB1 mRNA]; protocatechualdehyde inhibits the reaction [Glucose results in increased expression of TGFB1 protein]; protocatechualdehyde inhibits the reaction [S100B protein results in increased expression of TGFB1 mRNA]; protocatechualdehyde inhibits the reaction [S100B protein results in increased expression of TGFB1 protein]; protocatechualdehyde inhibits the reaction [TGFB1 protein results in decreased expression of AGER protein]; protocatechualdehyde inhibits the reaction [TGFB1 protein results in decreased expression of CDH1 protein]; protocatechualdehyde inhibits the reaction [TGFB1 protein results in increased expression of FGF2 protein]; protocatechualdehyde inhibits the reaction [TGFB1 protein results in increased expression of HMGB1 protein]; protocatechualdehyde inhibits the reaction [TGFB1 protein results in increased expression of VIM protein] CTD PMID:17597607, PMID:25582705 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Vim vimentin multiple interactions ISO protocatechualdehyde inhibits the reaction [TGFB1 protein results in increased expression of VIM protein] CTD PMID:25582705 NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212
JBrowse link
3-hydroxybenzaldehyde term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh2 aldehyde dehydrogenase 2 family member increases metabolic processing ISO ALDH2 protein results in increased metabolism of 3-hydroxybenzaldehyde CTD PMID:11744614 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
4-(diethylamino)benzaldehyde term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 decreases activity
multiple interactions
increases oxidation
ISO 4-(diethylamino)benzaldehyde results in decreased activity of ALDH1A1 protein
4-(diethylamino)benzaldehyde inhibits the reaction [ALDH1A1 protein results in decreased susceptibility to mafosfamide]
ALDH1A1 protein results in increased oxidation of 4-(diethylamino)benzaldehyde
CTD PMID:8662658, PMID:16316642, PMID:25512087 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 multiple interactions ISO 4-(diethylamino)benzaldehyde binds to and results in decreased activity of ALDH1A2 protein CTD PMID:25512087 NCBI chr 8:77,640,234...77,719,488
Ensembl chr 8:77,640,222...77,719,489
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member multiple interactions ISO 4-(diethylamino)benzaldehyde binds to and results in decreased activity of ALDH2 protein CTD PMID:25512087 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 increases oxidation ISO ALDH3A1 protein results in increased oxidation of 4-(diethylamino)benzaldehyde CTD PMID:25512087 NCBI chr10:47,490,168...47,499,855
Ensembl chr10:47,490,153...47,499,876
JBrowse link
4-nitrobenzaldehyde term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1a1 aldo-keto reductase family 1 member A1 increases reduction ISO AKR1A1 protein results in increased reduction of 4-nitrobenzaldehyde CTD PMID:10510318 NCBI chr 5:135,482,068...135,498,693
Ensembl chr 5:135,482,068...135,498,822
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B increases reduction ISO AKR1B1 protein results in increased reduction of 4-nitrobenzaldehyde CTD PMID:10510318 NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956
JBrowse link
G Akr1b7 aldo-keto reductase family 1, member B7 increases metabolic processing ISO AKR1B15 protein results in increased metabolism of 4-nitrobenzaldehyde CTD PMID:21276782 NCBI chr 4:61,850,256...61,879,733
Ensembl chr 4:61,850,348...61,862,526
JBrowse link
G Akr1b8 aldo-keto reductase family 1, member B8 multiple interactions EXP [AKR1B8 protein co-treated with NADP] affects the reduction of 4-nitrobenzaldehyde CTD PMID:18845131 NCBI chr 4:61,772,064...61,784,637
Ensembl chr 4:61,771,970...61,828,657
JBrowse link
G Akr7a2 aldo-keto reductase family 7, member A2 multiple interactions
affects reduction
ISO Ethacrynic Acid inhibits the reaction [4-nitrobenzaldehyde affects the reduction of AKR7A5 protein]; Indomethacin inhibits the reaction [4-nitrobenzaldehyde affects the reduction of AKR7A5 protein]; Quercetin inhibits the reaction [4-nitrobenzaldehyde affects the reduction of AKR7A5 protein]; Valproic Acid inhibits the reaction [4-nitrobenzaldehyde affects the reduction of AKR7A5 protein] CTD PMID:12604212 NCBI chr 5:157,759,448...157,768,473
Ensembl chr 5:157,759,416...157,768,471
JBrowse link
G Dhrs7 dehydrogenase/reductase 7 increases reduction ISO DHRS7 protein results in increased reduction of 4-nitrobenzaldehyde CTD PMID:24246760 NCBI chr 6:95,522,577...95,541,393
Ensembl chr 6:95,522,577...95,541,393
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions ISO NFE2L2 protein promotes the reaction [sulforafan results in decreased susceptibility to 4-nitrobenzaldehyde] CTD PMID:20932822 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
5-hydroxymethylfurfural term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nphs1 NPHS1 adhesion molecule, nephrin decreases expression EXP 5-hydroxymethylfurfural co-treated with 3,4-dideoxyglucosone co-treated with Glyoxal co-treated with Methylglyoxal cotreated with 3-deoxyglucosone co-treated with Formaldehyde co-treated with acetaldehyde decreases expression of Nphs1 protein in kidneys RGD PMID:18346151 RGD:38599007 NCBI chr 1:88,922,346...88,950,560
Ensembl chr 1:88,922,433...88,950,559
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 affects metabolic processing
increases metabolic processing
increases activity
multiple interactions
affects activity
ISO
EXP
SULT1A1 protein affects the metabolism of 5-hydroxymethylfurfural
SULT1A1 protein results in increased metabolism of 5-hydroxymethylfurfural
SULT1A1 protein results in increased activity of 5-hydroxymethylfurfural
[SULT1A1 protein co-treated with SULT1A2 protein] results in increased susceptibility to 5-hydroxymethylfurfural
5-hydroxymethylfurfural affects the activity of SULT1A1 protein
CTD PMID:22006426, PMID:22349055, PMID:22563731, PMID:25370010 NCBI chr 1:198,100,586...198,104,106
Ensembl chr 1:198,100,586...198,104,109
JBrowse link
benzaldehyde term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1b8 aldo-keto reductase family 1, member B8 multiple interactions EXP [AKR1B8 protein co-treated with NADP] affects the reduction of benzaldehyde CTD PMID:18845131 NCBI chr 4:61,772,064...61,784,637
Ensembl chr 4:61,771,970...61,828,657
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases oxidation
increases metabolic processing
EXP
ISO
ALDH1A1 protein results in increased oxidation of benzaldehyde
ALDH1A1 protein results in increased metabolism of benzaldehyde
CTD PMID:10998257, PMID:21256123 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member increases metabolic processing
multiple interactions
ISO ALDH2 protein results in increased metabolism of benzaldehyde
benzaldehyde inhibits the reaction [4-dimethylaminocinnamaldehyde binds to ALDH2 protein]
CTD PMID:10609638, PMID:11744614 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 multiple interactions
increases oxidation
increases metabolic processing
ISO [ALDH3A1 protein co-treated with NAD] results in increased oxidation of benzaldehyde; [ALDH3A1 protein co-treated with NADP] results in increased oxidation of benzaldehyde; Cimetidine inhibits the reaction [ALDH3A1 protein results in increased oxidation of benzaldehyde]
ALDH3A1 protein results in increased metabolism of benzaldehyde
CTD PMID:10856427, PMID:21256123, PMID:21349255, PMID:23220590, PMID:25512087 NCBI chr10:47,490,168...47,499,855
Ensembl chr10:47,490,153...47,499,876
JBrowse link
G Aldh3b1 aldehyde dehydrogenase 3 family, member B1 affects binding ISO benzaldehyde binds to ALDH3B1 protein CTD PMID:20699116 NCBI chr 1:219,145,457...219,181,536
Ensembl chr 1:219,145,459...219,186,860
JBrowse link
G Ar androgen receptor multiple interactions EXP benzaldehyde inhibits the reaction [Metribolone binds to AR protein] CTD PMID:3695475 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Slc2a1 solute carrier family 2 member 1 increases activity
multiple interactions
ISO benzaldehyde results in increased activity of SLC2A1 protein
[benzaldehyde co-treated with Glucose deficiency] results in decreased activity of SLC2A1 protein
CTD PMID:20955755 NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897
JBrowse link
benzaldehydes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 decreases activity ISO Benzaldehydes results in decreased activity of ALDH1A2 protein CTD PMID:22079344 NCBI chr 8:77,640,234...77,719,488
Ensembl chr 8:77,640,222...77,719,489
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member decreases activity ISO Benzaldehydes results in decreased activity of ALDH2 protein CTD PMID:22079344 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
ethyl vanillin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC100912605 olfactory receptor 5D14-like multiple interactions ISO [ethyl vanillin binds to and results in increased activity of OLFR73 protein] which results in increased transport of Calcium; ethyl vanillin binds to and results in increased activity of OLFR73 protein CTD PMID:15716417 NCBI chr 3:76,255,179...76,256,129
Ensembl chr 3:76,255,179...76,256,129
JBrowse link
G Trpv3 transient receptor potential cation channel, subfamily V, member 3 increases activity ISO ethyl vanillin results in increased activity of TRPV3 protein CTD PMID:16617338 NCBI chr10:59,829,755...59,863,780
Ensembl chr10:59,831,241...59,860,987
JBrowse link
m-tolualdehyde term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 decreases activity EXP 3-methylbenzaldehyde results in decreased activity of CYP2B1 protein CTD PMID:12791539 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases activity EXP 3-methylbenzaldehyde results in decreased activity of CYP2E1 protein CTD PMID:12791539 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 affects activity EXP 3-methylbenzaldehyde affects the activity of CYP4B1 protein CTD PMID:12791539 NCBI chr 5:134,508,728...134,526,103
Ensembl chr 5:134,508,730...134,526,089
JBrowse link
ortho-vanillin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 increases glucuronidation ISO UGT1A3 protein results in increased glucuronidation of 2-vanillin CTD PMID:15117964 NCBI chr 9:95,285,592...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a8 UDP glucuronosyltransferase family 1 member A8 increases glucuronidation ISO UGT1A8 protein results in increased glucuronidation of 2-vanillin CTD PMID:15117964 NCBI chr 9:95,221,474...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
p-methoxybenzaldehyde term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 increases activity ISO 4-anisaldehyde results in increased activity of TRPA1 protein CTD PMID:21591660 NCBI chr 5:3,783,247...3,836,485
Ensembl chr 5:3,783,247...3,836,485
JBrowse link
p-tolualdehyde term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions ISO 4-methylbenzaldehyde binds to and results in decreased activity of AHR protein CTD PMID:27633901 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Ar androgen receptor multiple interactions ISO 4-methylbenzaldehyde binds to and results in decreased activity of AR protein CTD PMID:27633901 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO 4-methylbenzaldehyde binds to and results in decreased activity of ESR2 protein CTD PMID:27633901 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO 4-methylbenzaldehyde analog inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; 4-methylbenzaldehyde analog inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]; 4-methylbenzaldehyde analog inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of IL1B protein] CTD PMID:27569861 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 multiple interactions ISO 4-methylbenzaldehyde analog inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; 4-methylbenzaldehyde analog inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein] CTD PMID:27569861 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO 4-methylbenzaldehyde analog inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein] CTD PMID:27569861 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO 4-methylbenzaldehyde analog inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein] CTD PMID:27569861 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO 4-methylbenzaldehyde analog inhibits the reaction [Lipopolysaccharides affects the localization of NFKB1 protein] CTD PMID:27569861 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO 4-methylbenzaldehyde analog inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased degradation of NFKBIA protein] CTD PMID:27569861 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO 4-methylbenzaldehyde analog inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; 4-methylbenzaldehyde analog inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:27569861 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Pgr progesterone receptor multiple interactions ISO 4-methylbenzaldehyde binds to and results in decreased activity of PGR protein CTD PMID:27633901 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO 4-methylbenzaldehyde binds to and results in decreased activity of PPARG protein CTD PMID:27633901 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO 4-methylbenzaldehyde analog inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; 4-methylbenzaldehyde analog inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] CTD PMID:27569861 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO 4-methylbenzaldehyde analog inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein] CTD PMID:27569861 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO 4-methylbenzaldehyde analog inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; 4-methylbenzaldehyde analog inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] CTD PMID:27569861 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
phthalaldehyde term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aicda activation-induced cytidine deaminase affects expression ISO o-Phthalaldehyde affects the expression of AICDA mRNA CTD PMID:22302311 NCBI chr 4:155,359,909...155,371,104
Ensembl chr 4:155,359,921...155,369,671
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 affects expression ISO o-Phthalaldehyde affects the expression of AKR1C18 mRNA CTD PMID:22302311 NCBI chr17:69,761,126...69,778,021
Ensembl chr17:69,761,118...69,778,021
JBrowse link
G Ccl6 chemokine (C-C motif) ligand 6 affects expression ISO o-Phthalaldehyde affects the expression of CCL6 mRNA CTD PMID:22302311 NCBI chr10:70,798,118...70,802,750
Ensembl chr10:70,797,124...70,802,782
JBrowse link
G Ccna2 cyclin A2 affects expression ISO o-Phthalaldehyde affects the expression of CCNA2 mRNA CTD PMID:22302311 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214
JBrowse link
G Ccnb1 cyclin B1 affects expression ISO o-Phthalaldehyde affects the expression of CCNB1 mRNA CTD PMID:22302311 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Ccne2 cyclin E2 affects expression ISO o-Phthalaldehyde affects the expression of CCNE2 mRNA CTD PMID:22302311 NCBI chr 5:24,434,077...24,446,406
Ensembl chr 5:24,434,872...24,446,406
JBrowse link
G Ccr4 C-C motif chemokine receptor 4 affects expression ISO o-Phthalaldehyde affects the expression of CCR4 mRNA CTD PMID:22302311 NCBI chr 8:122,530,152...122,535,959
Ensembl chr 8:122,530,624...122,532,070
JBrowse link
G Cd207 CD207 molecule affects expression ISO o-Phthalaldehyde affects the expression of CD207 mRNA CTD PMID:22302311 NCBI chr 4:115,333,124...115,355,034
Ensembl chr 4:115,348,491...115,354,795
JBrowse link
G Cd5l Cd5 molecule-like affects expression ISO o-Phthalaldehyde affects the expression of CD5L mRNA CTD PMID:22302311 NCBI chr 2:186,685,104...186,696,117
Ensembl chr 2:186,685,104...186,696,117
JBrowse link
G Cd83 CD83 molecule affects expression ISO o-Phthalaldehyde affects the expression of CD83 mRNA CTD PMID:22302311 NCBI chr17:24,416,651...24,435,790
Ensembl chr17:24,416,651...24,435,790
JBrowse link
G Cdc20 cell division cycle 20 affects expression ISO o-Phthalaldehyde affects the expression of CDC20 mRNA CTD PMID:22302311 NCBI chr 5:137,260,728...137,264,931
Ensembl chr 5:137,260,739...137,265,015
JBrowse link
G Cdc25c cell division cycle 25C affects expression ISO o-Phthalaldehyde affects the expression of CDC25C mRNA CTD PMID:22302311 NCBI chr18:27,528,768...27,550,316
Ensembl chr18:27,528,354...27,550,224
JBrowse link
G Cdk1 cyclin-dependent kinase 1 affects expression ISO o-Phthalaldehyde affects the expression of CDK1 mRNA CTD PMID:22302311 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
JBrowse link
G Clec7a C-type lectin domain containing 7A affects expression ISO o-Phthalaldehyde affects the expression of CLEC7A mRNA CTD PMID:22302311 NCBI chr 4:163,216,152...163,227,367
Ensembl chr 4:163,216,163...163,227,334
JBrowse link
G Col8a1 collagen type VIII alpha 1 chain affects expression ISO o-Phthalaldehyde affects the expression of COL8A1 mRNA CTD PMID:22302311 NCBI chr11:44,877,690...45,006,203
Ensembl chr11:44,877,859...45,007,891
JBrowse link
G Cphx1 cytoplasmic polyadenylated homeobox 1 affects expression ISO o-Phthalaldehyde affects the expression of CPHX1 mRNA CTD PMID:22302311 NCBI chr16:3,787,141...3,796,715
Ensembl chr16:3,786,686...3,796,047
JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 affects expression ISO o-Phthalaldehyde affects the expression of CTLA4 mRNA CTD PMID:22302311 NCBI chr 9:67,699,397...67,706,068
Ensembl chr 9:67,699,379...67,706,065
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases expression ISO o-Phthalaldehyde results in decreased expression of CYP1A1 mRNA CTD PMID:20112102 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases expression ISO o-Phthalaldehyde results in decreased expression of CYP2E1 mRNA CTD PMID:20112102 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Dio1 iodothyronine deiodinase 1 decreases activity ISO o-Phthalaldehyde results in decreased activity of DIO1 protein CTD PMID:30561685 NCBI chr 5:126,894,837...126,911,532
Ensembl chr 5:126,895,286...126,911,520
JBrowse link
G Dio2 iodothyronine deiodinase 2 decreases activity ISO o-Phthalaldehyde results in decreased activity of DIO2 protein CTD PMID:30561685 NCBI chr 6:114,475,156...114,489,443
Ensembl chr 6:114,476,142...114,476,723
JBrowse link
G Dio3 iodothyronine deiodinase 3 decreases activity ISO o-Phthalaldehyde results in decreased activity of DIO3 protein CTD PMID:30561685 NCBI chr 6:134,627,278...134,629,139
Ensembl chr 6:134,627,278...134,629,138
JBrowse link
G E2f1 E2F transcription factor 1 affects expression ISO o-Phthalaldehyde affects the expression of E2F1 mRNA CTD PMID:22302311 NCBI chr 3:150,062,895...150,073,721
Ensembl chr 3:150,047,826...150,073,721
JBrowse link
G Fabp7 fatty acid binding protein 7 affects expression ISO o-Phthalaldehyde affects the expression of FABP7 mRNA CTD PMID:22302311 NCBI chr20:40,769,624...40,773,156
Ensembl chr20:40,769,586...40,773,349
JBrowse link
G Fxyd4 FXYD domain-containing ion transport regulator 4 affects expression ISO o-Phthalaldehyde affects the expression of FXYD4 mRNA CTD PMID:22302311 NCBI chr 4:149,984,206...149,988,744
Ensembl chr 4:149,984,206...149,988,295
JBrowse link
G Gzmb granzyme B affects expression ISO o-Phthalaldehyde affects the expression of GZMB mRNA CTD PMID:22302311 NCBI chr15:35,413,862...35,417,293
Ensembl chr15:35,413,793...35,417,316
JBrowse link
G Ifng interferon gamma increases expression ISO o-Phthalaldehyde results in increased expression of IFNG mRNA CTD PMID:21785612 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il10 interleukin 10 increases expression ISO o-Phthalaldehyde results in increased expression of IL10 mRNA CTD PMID:21785612 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il12b interleukin 12B affects expression ISO o-Phthalaldehyde affects the expression of IL12B mRNA CTD PMID:22302311 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
JBrowse link
G Il13 interleukin 13 increases expression ISO o-Phthalaldehyde results in increased expression of IL13 mRNA CTD PMID:21785612 NCBI chr10:38,982,909...38,985,466
Ensembl chr10:38,982,909...38,985,466
JBrowse link
G Il1b interleukin 1 beta increases expression ISO o-Phthalaldehyde results in increased expression of IL1B mRNA CTD PMID:21785612 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il21 interleukin 21 affects expression ISO o-Phthalaldehyde affects the expression of IL21 mRNA CTD PMID:22302311 NCBI chr 2:123,965,021...123,972,356
Ensembl chr 2:123,965,021...123,972,356
JBrowse link
G Il2ra interleukin 2 receptor subunit alpha affects expression ISO o-Phthalaldehyde affects the expression of IL2RA mRNA CTD PMID:22302311 NCBI chr17:70,500,672...70,547,929
Ensembl chr17:70,499,083...70,548,071
JBrowse link
G Il4 interleukin 4 affects expression
increases expression
ISO o-Phthalaldehyde affects the expression of IL4 mRNA
o-Phthalaldehyde results in increased expression of IL4 mRNA; o-Phthalaldehyde results in increased expression of IL4 protein
CTD PMID:19110043, PMID:20176622, PMID:21785612, PMID:22302311 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il5 interleukin 5 increases expression ISO o-Phthalaldehyde results in increased expression of IL5 mRNA CTD PMID:19110043, PMID:21785612 NCBI chr10:39,066,716...39,069,587
Ensembl chr10:39,066,716...39,069,587
JBrowse link
G Itgav integrin subunit alpha V affects expression ISO o-Phthalaldehyde affects the expression of ITGAV mRNA CTD PMID:22302311 NCBI chr 3:71,113,269...71,205,958
Ensembl chr 3:71,114,100...71,202,411
JBrowse link
G Lgals7 galectin 7 affects expression ISO o-Phthalaldehyde affects the expression of LGALS7 mRNA CTD PMID:22302311 NCBI chr 1:87,044,823...87,047,223
Ensembl chr 1:87,045,335...87,047,223
JBrowse link
G Mki67 marker of proliferation Ki-67 affects expression ISO o-Phthalaldehyde affects the expression of MKI67 mRNA CTD PMID:22302311 NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454
JBrowse link
G Nts neurotensin affects expression ISO o-Phthalaldehyde affects the expression of NTS mRNA CTD PMID:22302311 NCBI chr 7:44,111,594...44,120,998
Ensembl chr 7:44,111,151...44,121,130
JBrowse link
G Thbs1 thrombospondin 1 affects expression ISO o-Phthalaldehyde affects the expression of THBS1 mRNA CTD PMID:22302311 NCBI chr 3:109,862,120...109,873,466
Ensembl chr 3:109,862,117...109,873,466
JBrowse link
G Thbs4 thrombospondin 4 affects expression ISO o-Phthalaldehyde affects the expression of THBS4 mRNA CTD PMID:22302311 NCBI chr 2:22,343,727...22,385,855
Ensembl chr 2:22,343,727...22,385,855
JBrowse link
G Timd2 T-cell immunoglobulin and mucin domain containing 2 affects expression ISO o-Phthalaldehyde affects the expression of TIMD2 mRNA CTD PMID:22302311 NCBI chr10:31,755,473...31,796,423
Ensembl chr10:31,755,510...31,790,263
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 affects expression ISO o-Phthalaldehyde affects the expression of TIMP1 mRNA CTD PMID:22302311 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Tnf tumor necrosis factor increases expression ISO o-Phthalaldehyde results in increased expression of TNF mRNA CTD PMID:21785612 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Trpm6 transient receptor potential cation channel, subfamily M, member 6 affects expression ISO o-Phthalaldehyde affects the expression of TRPM6 mRNA CTD PMID:22302311 NCBI chr 1:234,478,908...234,631,264
Ensembl chr 1:234,479,289...234,596,971
JBrowse link
vanillin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c2 aldo-keto reductase family 1, member C2 increases expression ISO vanillin results in increased expression of AKR1C2 mRNA CTD PMID:20491607 NCBI chr17:69,388,337...69,435,160
Ensembl chr17:69,388,335...69,404,341
JBrowse link
G Car1 carbonic anhydrase 1 decreases activity ISO vanillin results in decreased activity of CA1 protein CTD PMID:19231207 NCBI chr 2:88,185,204...88,227,486
Ensembl chr 2:88,217,188...88,227,479
JBrowse link
G Car2 carbonic anhydrase 2 decreases activity ISO vanillin results in decreased activity of CA2 protein CTD PMID:19231207 NCBI chr 2:88,097,740...88,112,868
Ensembl chr 2:88,097,720...88,113,029
JBrowse link
G Cat catalase multiple interactions ISO vanillin inhibits the reaction [potassium bromate results in increased activity of CAT protein] CTD PMID:26296324 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccn2 cellular communication network factor 2 decreases expression ISO vanillin results in decreased expression of CCN2 mRNA CTD PMID:17178418 NCBI chr 1:21,851,657...21,854,773
Ensembl chr 1:21,851,660...21,854,773
JBrowse link
G Clk2 CDC-like kinase 2 increases expression ISO vanillin results in increased expression of CLK2 mRNA CTD PMID:17178418 NCBI chr 2:188,476,789...188,488,809
Ensembl chr 2:188,476,820...188,496,191
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO vanillin results in increased expression of CYP1A1 mRNA CTD PMID:20491607 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression ISO vanillin results in increased expression of DDIT4 mRNA CTD PMID:17178418 NCBI chr20:29,509,283...29,511,382
Ensembl chr20:29,509,289...29,511,382
JBrowse link
G Dnmt3b DNA methyltransferase 3 beta decreases expression ISO vanillin results in decreased expression of DNMT3B mRNA CTD PMID:17178418 NCBI chr 3:149,131,541...149,170,061
Ensembl chr 3:149,131,785...149,208,786
JBrowse link
G Dusp6 dual specificity phosphatase 6 decreases expression ISO vanillin results in decreased expression of DUSP6 mRNA CTD PMID:17178418 NCBI chr 7:41,475,163...41,479,393
Ensembl chr 7:41,475,163...41,479,392
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 decreases expression ISO vanillin results in decreased expression of FGFR2 mRNA CTD PMID:17178418 NCBI chr 1:200,590,951...200,696,946
Ensembl chr 1:200,590,953...200,696,928
JBrowse link
G Fzd2 frizzled class receptor 2 decreases expression ISO vanillin results in decreased expression of FZD2 mRNA CTD PMID:17178418 NCBI chr10:90,550,147...90,552,057
Ensembl chr10:90,550,147...90,552,057
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO vanillin results in increased expression of GCLC mRNA CTD PMID:17178418 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO vanillin results in increased expression of GCLM mRNA CTD PMID:17178418 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO vanillin results in increased expression of HMOX1 mRNA CTD PMID:17178418 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 decreases mutagenesis ISO vanillin results in decreased mutagenesis of HPRT1 gene CTD PMID:17178418 NCBI chr  X:158,196,640...158,228,815
Ensembl chr  X:158,197,149...158,228,749
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B increases expression ISO vanillin results in increased expression of HSPA1B mRNA CTD PMID:17178418 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO vanillin inhibits the reaction [potassium bromate results in increased expression of IL1B mRNA] CTD PMID:26296324 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 multiple interactions ISO vanillin inhibits the reaction [potassium bromate results in increased expression of IL6 mRNA] CTD PMID:26296324 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Insig1 insulin induced gene 1 decreases expression ISO vanillin results in decreased expression of INSIG1 mRNA CTD PMID:17178418 NCBI chr 4:342,302...350,515
Ensembl chr 4:342,302...350,515
JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit decreases expression ISO vanillin results in decreased expression of JUND mRNA CTD PMID:17178418 NCBI chr16:20,485,028...20,486,707
Ensembl chr16:20,485,029...20,486,707
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 decreases expression ISO vanillin results in decreased expression of MAP2K2 mRNA CTD PMID:17178418 NCBI chr 7:11,458,971...11,478,520
Ensembl chr 7:11,458,967...11,478,489
JBrowse link
G Mark4 microtubule affinity regulating kinase 4 decreases expression ISO vanillin results in decreased expression of MARK4 mRNA CTD PMID:17178418 NCBI chr 1:80,335,517...80,367,366
Ensembl chr 1:80,335,526...80,367,328
JBrowse link
G Mt1 metallothionein 1 multiple interactions ISO vanillin inhibits the reaction [potassium bromate results in increased expression of MT1 mRNA] CTD PMID:27074584 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
JBrowse link
G Mt2A metallothionein 2A increases expression
multiple interactions
ISO vanillin results in increased expression of MT2A mRNA
vanillin inhibits the reaction [potassium bromate results in increased expression of MT2 mRNA]
CTD PMID:20491607, PMID:27074584 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Ppp1r10 protein phosphatase 1, regulatory subunit 10 decreases expression ISO vanillin results in decreased expression of PPP1R10 mRNA CTD PMID:17178418 NCBI chr20:3,329,677...3,344,286
Ensembl chr20:3,329,677...3,344,286
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO vanillin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; vanillin inhibits the reaction [potassium bromate results in increased expression of PTGS2 mRNA] CTD PMID:17465205, PMID:26296324 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Slc35d2 solute carrier family 35 member D2 decreases expression ISO vanillin results in decreased expression of SLC35D2 mRNA CTD PMID:17178418 NCBI chr17:1,618,641...1,649,734
Ensembl chr17:1,618,189...1,648,973
JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO vanillin results in increased expression of SLC7A11 mRNA CTD PMID:17178418 NCBI chr 2:139,453,774...139,528,479
Ensembl chr 2:139,453,774...139,528,162
JBrowse link
G Tgfb1i1 transforming growth factor beta 1 induced transcript 1 decreases expression ISO vanillin results in decreased expression of TGFB1I1 mRNA CTD PMID:17178418 NCBI chr 1:199,664,039...199,670,970
Ensembl chr 1:199,664,173...199,670,961
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO vanillin inhibits the reaction [potassium bromate results in increased expression of TNF mRNA] CTD PMID:26296324 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tp53 tumor protein p53 decreases expression ISO vanillin results in decreased expression of TP53 mRNA CTD PMID:17178418 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Trim16 tripartite motif-containing 16 increases expression ISO vanillin results in increased expression of TRIM16 mRNA CTD PMID:17178418 NCBI chr10:49,231,660...49,254,653
Ensembl chr10:49,231,730...49,254,621
JBrowse link
G Trpv3 transient receptor potential cation channel, subfamily V, member 3 increases activity ISO vanillin results in increased activity of TRPV3 protein CTD PMID:16617338 NCBI chr10:59,829,755...59,863,780
Ensembl chr10:59,831,241...59,860,987
JBrowse link
G Ugp2 UDP-glucose pyrophosphorylase 2 increases expression ISO vanillin results in increased expression of UGP2 mRNA CTD PMID:17178418 NCBI chr14:106,208,174...106,249,322
Ensembl chr14:106,208,176...106,248,539
JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 increases glucuronidation ISO UGT1A3 protein results in increased glucuronidation of vanillin CTD PMID:15117964 NCBI chr 9:95,285,592...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a8 UDP glucuronosyltransferase family 1 member A8 increases glucuronidation ISO UGT1A8 protein results in increased glucuronidation of vanillin CTD PMID:15117964 NCBI chr 9:95,221,474...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19770
    role 19718
      application 19363
        solvent 16419
          formic acid 7874
            formyl group 7840
              aldehyde 7840
                arenecarbaldehyde 123
                  1,3-thiazole-2-carbaldehyde + 0
                  1-acetylindole-3-carboxaldehyde 0
                  2,5-diformylfuran 0
                  2,5-dimethyl-1-(phenylmethyl)pyrrole-3,4-dicarboxaldehyde 0
                  2-(dihydroxymethyl)-5-formylfuran 0
                  2-oxo-4-(4-propan-2-yl-1-pyridin-1-iumyl)-3H-thiazole-5-carboxaldehyde 0
                  4'-methyl-2,2'-bipyridine-4-carboxaldehyde 0
                  4-(phosphooxymethyl)-2-furancarboxaldehyde 0
                  5-Methyl-2-furaldehyde 0
                  5-formyl-2-furoic acid 0
                  5-hydroxymethylfurfural 1
                  8-formyl-8-demethylriboflavin 5'-phosphate 0
                  Baldrinal 0
                  aromatic (S)-hydroxynitrile 0
                  benzaldehydes + 122
                  cyathusal A 0
                  cyathusal B 0
                  cyathusal C 0
                  demethylzeylasteral 0
                  grixazone A 0
                  kadsurenin M 0
                  mycobilin a 0
                  mycobilin b 0
                  naphthaldehydes + 1
                  piperonal 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19770
    subatomic particle 19768
      composite particle 19768
        hadron 19768
          baryon 19768
            nucleon 19768
              atomic nucleus 19768
                atom 19768
                  main group element atom 19655
                    p-block element atom 19655
                      carbon group element atom 19550
                        carbon atom 19539
                          organic molecular entity 19539
                            organic group 18488
                              organic divalent group 18481
                                organodiyl group 18481
                                  carbonyl group 18384
                                    carbonyl compound 18384
                                      carboxylic acid 18054
                                        carboacyl group 17334
                                          univalent carboacyl group 17334
                                            formyl group 7840
                                              aldehyde 7840
                                                arenecarbaldehyde 123
                                                  1,3-thiazole-2-carbaldehyde + 0
                                                  1-acetylindole-3-carboxaldehyde 0
                                                  2,5-diformylfuran 0
                                                  2,5-dimethyl-1-(phenylmethyl)pyrrole-3,4-dicarboxaldehyde 0
                                                  2-(dihydroxymethyl)-5-formylfuran 0
                                                  2-oxo-4-(4-propan-2-yl-1-pyridin-1-iumyl)-3H-thiazole-5-carboxaldehyde 0
                                                  4'-methyl-2,2'-bipyridine-4-carboxaldehyde 0
                                                  4-(phosphooxymethyl)-2-furancarboxaldehyde 0
                                                  5-Methyl-2-furaldehyde 0
                                                  5-formyl-2-furoic acid 0
                                                  5-hydroxymethylfurfural 1
                                                  8-formyl-8-demethylriboflavin 5'-phosphate 0
                                                  Baldrinal 0
                                                  aromatic (S)-hydroxynitrile 0
                                                  benzaldehydes + 122
                                                  cyathusal A 0
                                                  cyathusal B 0
                                                  cyathusal C 0
                                                  demethylzeylasteral 0
                                                  grixazone A 0
                                                  kadsurenin M 0
                                                  mycobilin a 0
                                                  mycobilin b 0
                                                  naphthaldehydes + 1
                                                  piperonal 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.