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ONTOLOGY REPORT - ANNOTATIONS


Term:14,15-EET
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Accession:CHEBI:34157 term browser browse the term
Definition:An EET obtained by formal epoxidation of the 14,15-double bond of arachidonic acid.
Synonyms:exact_synonym: (5Z,8Z,11Z)-13-(3-pentyloxiran-2-yl)trideca-5,8,11-trienoic acid
 related_synonym: (5Z,8Z,11Z)-14,15-Epoxyeicosa-5.8.11-trienoic acid;   (5Z,8Z,11Z)-14,15-Epoxyicosa-5.8.11-trienoic acid;   14,15-EpETrE;   14,15-epoxy-5Z,8Z,11Z-eicosatrienoic acid;   14,15-epoxy-5Z,8Z,11Z-icosatrienoic acid;   Formula=C20H32O3;   InChI=1S/C20H32O3/c1-2-3-12-15-18-19(23-18)16-13-10-8-6-4-5-7-9-11-14-17-20(21)22/h4,6-7,9-10,13,18-19H,2-3,5,8,11-12,14-17H2,1H3,(H,21,22)/b6-4-,9-7-,13-10-;   InChIKey=JBSCUHKPLGKXKH-ILYOTBPNSA-N;   SMILES=CCCCCC1OC1C\\C=C/C\\C=C/C\\C=C/CCCC(O)=O;   all-cis-14,15-epoxyeicosa-5,8,11-trienoic acid
 xref: HMDB:HMDB0004264;   KEGG:C14771;   LIPID_MAPS_instance:LMFA03080005 "LIPID MAPS"
 xref_mesh: MESH:C046782
 xref: PMID:19653681 "Europe PMC";   Reaxys:4703440 "Reaxys"
 cyclic_relationship: is_conjugate_acid_of CHEBI:84024


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14,15-EET term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ace angiotensin I converting enzyme JBrowse link 10 94,170,766 94,213,831 RGD:6480464
G Ace2 angiotensin I converting enzyme 2 JBrowse link X 32,050,734 32,095,860 RGD:6480464
G Agt angiotensinogen JBrowse link 19 57,321,594 57,333,460 RGD:6480464
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:6480464
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 JBrowse link 1 147,236,480 147,307,988 RGD:6480464
G Ephx2 epoxide hydrolase 2 JBrowse link 15 42,757,241 42,794,211 RGD:6480464
G Fgf2 fibroblast growth factor 2 JBrowse link 2 124,081,072 124,134,133 RGD:6480464
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6480464
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6480464
G Rps6kb1 ribosomal protein S6 kinase B1 JBrowse link 10 73,824,200 73,865,503 RGD:6480464
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      biological role 19611
        biochemical role 19138
          metabolite 19106
            EET 12
              14,15-EET 11
                (14R,15S)-EET 0
                (14S,15R)-EET 0
                14,15-epoxy-(5Z,8Z,11Z)-icosatrienoyl-CoA 0
                2-glyceryl 14,15-epoxy-(5Z,8Z,11Z)-icosatrienoate 0
                N-[(5Z,8Z,11Z)-14,15-epoxyicosatrienoyl]ethanolamine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    p-block element atom 19545
                      carbon group element atom 19428
                        carbon atom 19420
                          organic molecular entity 19420
                            organic group 18343
                              organic divalent group 18334
                                organodiyl group 18334
                                  carbonyl group 18222
                                    carbonyl compound 18222
                                      carboxylic acid 17923
                                        monocarboxylic acid 17256
                                          fatty acid 15814
                                            unsaturated fatty acid 888
                                              polyunsaturated fatty acid 646
                                                fatty acid 20:4 309
                                                  icosatetraenoic acid 309
                                                    icosa-5,8,11,14-tetraenoic acid 260
                                                      arachidonic acid 260
                                                        EET 12
                                                          14,15-EET 11
                                                            (14R,15S)-EET 0
                                                            (14S,15R)-EET 0
                                                            14,15-epoxy-(5Z,8Z,11Z)-icosatrienoyl-CoA 0
                                                            2-glyceryl 14,15-epoxy-(5Z,8Z,11Z)-icosatrienoate 0
                                                            N-[(5Z,8Z,11Z)-14,15-epoxyicosatrienoyl]ethanolamine 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.