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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:oxybenzone
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Accession:CHEBI:34283 term browser browse the term
Definition:A hydroxybenzophenone that is benzophenone which is substituted at the 2- and 4-positions of one of the benzene rings by hydroxy and methoxy groups respectively.
Synonyms:exact_synonym: (2-hydroxy-4-methoxyphenyl)(phenyl)methanone
 related_synonym: 2-Benzoyl-5-methoxyphenol;   2-Hydroxy-4-methoxybenzophenone;   4-Methoxy-2-hydroxybenzophenone;   Benzophenone-3;   Formula=C14H12O3;   InChI=1S/C14H12O3/c1-17-11-7-8-12(13(15)9-11)14(16)10-5-3-2-4-6-10/h2-9,15H,1H3;   InChIKey=DXGLGDHPHMLXJC-UHFFFAOYSA-N;   SMILES=COc1ccc(C(=O)c2ccccc2)c(O)c1;   oxibenzona;   oxybenzonum
 alt_id: CHEBI:569732
 xref: Beilstein:1913145;   CAS:131-57-7;   DrugBank:DB01428;   Drug_Central:3412;   HMDB:HMDB0015497;   KEGG:C14285;   KEGG:D05309;   LINCS:LSM-3309
 xref_mesh: MESH:C005290
 xref: PMID:11169173;   PMID:22721600;   PMID:26118430;   PMID:26167727;   PMID:26295590;   PMID:26487337;   PMID:26589946;   PMID:26686077;   PMID:26736174;   PMID:27085067;   PMID:27544106;   PMID:27796700;   PMID:28192168;   Patent:US2773903;   Patent:US2861104;   Patent:US2861105;   Patent:US3073866;   Reaxys:1913145;   Wikipedia:Oxybenzone


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oxybenzone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acad10 acyl-CoA dehydrogenase family, member 10 increases expression EXP oxybenzone results in increased expression of ACAD10 mRNA CTD PMID:30316929 NCBI chr12:40,417,918...40,460,562
Ensembl chr12:40,417,944...40,460,561
JBrowse link
G Acad9 acyl-CoA dehydrogenase family, member 9 increases expression EXP oxybenzone results in increased expression of ACAD9 mRNA CTD PMID:30316929 NCBI chr 2:122,782,051...122,806,166
Ensembl chr 2:122,782,060...122,805,768
JBrowse link
G Acbd3 acyl-CoA binding domain containing 3 decreases expression EXP oxybenzone results in decreased expression of ACBD3 mRNA CTD PMID:30316929 NCBI chr13:99,004,942...99,035,520
Ensembl chr13:99,004,942...99,035,519
JBrowse link
G Aco2 aconitase 2 affects expression EXP oxybenzone affects the expression of ACO2 mRNA CTD PMID:30316929 NCBI chr 7:123,102,493...123,145,608
Ensembl chr 7:123,102,468...123,145,635
JBrowse link
G Acot2 acyl-CoA thioesterase 2 increases expression EXP oxybenzone results in increased expression of ACOT2 mRNA CTD PMID:30316929 NCBI chr 6:107,460,596...107,468,324
Ensembl chr 6:107,460,668...107,467,487
JBrowse link
G Acox1 acyl-CoA oxidase 1 increases expression EXP oxybenzone results in increased expression of ACOX1 mRNA CTD PMID:30316929 NCBI chr10:104,724,534...104,748,003
Ensembl chr10:104,722,958...104,748,050
JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 decreases expression EXP oxybenzone results in decreased expression of ACSL5 mRNA CTD PMID:30316929 NCBI chr 1:276,240,703...276,290,012
Ensembl chr 1:276,240,703...276,290,008
JBrowse link
G Acss2 acyl-CoA synthetase short-chain family member 2 increases expression EXP oxybenzone results in increased expression of ACSS2 mRNA CTD PMID:30316929 NCBI chr 3:151,032,925...151,075,856
Ensembl chr 3:151,032,952...151,075,856
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions ISO oxybenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ mRNA]; oxybenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ protein] CTD PMID:32407875 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Adprhl1 ADP-ribosylhydrolase like 1 affects expression EXP oxybenzone affects the expression of ADPRHL1 mRNA CTD PMID:30316929 NCBI chr16:81,616,098...81,648,133
Ensembl chr16:81,616,604...81,632,030
JBrowse link
G Ahr aryl hydrocarbon receptor decreases expression
increases expression
EXP oxybenzone results in decreased expression of AHR mRNA
oxybenzone results in increased expression of AHR protein
CTD PMID:15458797, PMID:30099065 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Aif1 allograft inflammatory factor 1 increases expression EXP oxybenzone results in increased expression of AIF1 mRNA; oxybenzone results in increased expression of AIF1 protein CTD PMID:31368502 NCBI chr20:5,161,350...5,167,176
Ensembl chr20:5,161,333...5,166,448
JBrowse link
G Apoc3 apolipoprotein C3 increases expression EXP oxybenzone results in increased expression of APOC3 mRNA CTD PMID:30316929 NCBI chr 8:50,529,318...50,531,498
Ensembl chr 8:50,529,318...50,531,498
JBrowse link
G Aqp1 aquaporin 1 decreases expression EXP oxybenzone results in decreased expression of AQP1 mRNA CTD PMID:30316929 NCBI chr 4:85,551,503...85,563,683
Ensembl chr 4:85,551,502...85,569,360
JBrowse link
G Ar androgen receptor multiple interactions
affects localization
ISO
EXP
oxybenzone binds to and results in decreased activity of AR protein; oxybenzone inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]
oxybenzone affects the localization of AR protein
CTD PMID:12730620, PMID:15537743, PMID:15950433, PMID:30099065 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Areg amphiregulin increases expression ISO oxybenzone results in increased expression of AREG mRNA CTD PMID:31939680 NCBI chr14:18,521,921...18,531,179
Ensembl chr14:18,521,930...18,531,179
JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha increases expression EXP oxybenzone results in increased expression of ATP5A1 mRNA CTD PMID:30316929 NCBI chr18:74,156,553...74,164,490
Ensembl chr18:74,156,553...74,164,495
JBrowse link
G Atp5f1b ATP synthase F1 subunit beta increases expression EXP oxybenzone results in increased expression of ATP5B mRNA CTD PMID:30316929 NCBI chr 7:2,504,708...2,511,748
Ensembl chr 7:2,504,695...2,511,749
JBrowse link
G Atp5f1c ATP synthase F1 subunit gamma increases expression EXP oxybenzone results in increased expression of ATP5C1 mRNA CTD PMID:30316929 NCBI chr17:72,209,321...72,231,562
Ensembl chr17:72,209,373...72,394,271
JBrowse link
G Atp5mc2 ATP synthase membrane subunit c locus 2 decreases expression EXP oxybenzone results in decreased expression of ATP5G2 mRNA CTD PMID:30316929 NCBI chr 7:144,264,207...144,272,578
Ensembl chr 7:144,264,199...144,272,578
JBrowse link
G Bad BCL2-associated agonist of cell death increases expression EXP oxybenzone results in increased expression of BAD mRNA CTD PMID:30316929 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression EXP oxybenzone results in increased expression of BAK1 mRNA; oxybenzone results in increased expression of BAK1 protein CTD PMID:30099065, PMID:30316929 NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression EXP oxybenzone results in increased expression of BAX mRNA; oxybenzone results in increased expression of BAX protein CTD PMID:30099065, PMID:30316929 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression EXP oxybenzone results in decreased expression of BCL2L1 mRNA CTD PMID:30316929 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bcs1l BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone increases expression EXP oxybenzone results in increased expression of BCS1L mRNA CTD PMID:30316929 NCBI chr 9:81,868,158...81,872,201
Ensembl chr 9:81,868,265...81,872,197
JBrowse link
G Casp1 caspase 1 decreases expression EXP oxybenzone results in decreased expression of CASP1 mRNA CTD PMID:30316929 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Casp2 caspase 2 increases expression EXP oxybenzone results in increased expression of CASP2 mRNA CTD PMID:30316929 NCBI chr 4:71,652,358...71,670,228
Ensembl chr 4:71,652,354...71,670,239
JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
EXP oxybenzone results in increased activity of CASP3 protein
oxybenzone results in increased expression of and results in increased activity of CASP3 protein
CTD PMID:30099065, PMID:31368502 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp4 caspase 4 decreases expression EXP oxybenzone results in decreased expression of CASP4 mRNA CTD PMID:30316929 NCBI chr 8:2,616,391...2,651,682
Ensembl chr 8:2,635,851...2,651,652
JBrowse link
G Casp9 caspase 9 increases activity
increases expression
EXP oxybenzone results in increased activity of CASP9 protein
oxybenzone results in increased expression of CASP9 mRNA
CTD PMID:30099065, PMID:30316929 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Ccl21 C-C motif chemokine ligand 21 decreases expression EXP oxybenzone results in decreased expression of CCL21 mRNA CTD PMID:30316929 NCBI chr 5:58,197,678...58,198,782
Ensembl chr 5:58,197,680...58,198,782
JBrowse link
G Cited4 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4 increases expression EXP oxybenzone results in increased expression of CITED4 mRNA CTD PMID:30316929 NCBI chr 5:139,597,731...139,598,622
Ensembl chr 5:139,597,731...139,598,622
JBrowse link
G Cox15 cytochrome c oxidase assembly homolog COX15 increases expression EXP oxybenzone results in increased expression of COX15 mRNA CTD PMID:30316929 NCBI chr 1:263,494,850...263,511,510
Ensembl chr 1:263,494,852...263,511,505
JBrowse link
G Cox16 cytochrome c oxidase assembly factor COX16 decreases expression EXP oxybenzone results in decreased expression of COX16 mRNA CTD PMID:30316929 NCBI chr 6:105,195,387...105,214,366
Ensembl chr 6:105,201,395...105,214,329
JBrowse link
G Cox17 cytochrome c oxidase copper chaperone COX17 increases expression EXP oxybenzone results in increased expression of COX17 mRNA CTD PMID:30316929 NCBI chr11:64,962,663...64,968,437
Ensembl chr11:64,962,666...64,968,437
JBrowse link
G Cox18 cytochrome c oxidase assembly factor COX18 increases expression EXP oxybenzone results in increased expression of COX18 mRNA CTD PMID:30316929 NCBI chr14:19,434,728...19,446,379
Ensembl chr14:19,434,753...19,446,376
JBrowse link
G Cox5a cytochrome c oxidase subunit 5A increases expression EXP oxybenzone results in increased expression of COX5A mRNA CTD PMID:30316929 NCBI chr 8:62,298,358...62,309,765
Ensembl chr 8:62,298,358...62,309,765
JBrowse link
G Cox6b2 cytochrome c oxidase subunit 6B2 decreases expression EXP oxybenzone results in decreased expression of COX6B2 mRNA CTD PMID:30316929 NCBI chr 1:72,661,099...72,662,436
Ensembl chr 1:72,661,211...72,662,434
JBrowse link
G Cox7a2 cytochrome c oxidase subunit 7A2 decreases expression EXP oxybenzone results in decreased expression of COX7A2 mRNA CTD PMID:30316929 NCBI chr 8:87,209,529...87,213,627
Ensembl chr 8:87,209,530...87,213,627
JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B increases expression EXP oxybenzone results in increased expression of CPT1B mRNA CTD PMID:30316929 NCBI chr 7:130,395,211...130,404,731
Ensembl chr 7:130,395,194...130,405,347
JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 increases expression EXP oxybenzone results in increased expression of CPT2 mRNA CTD PMID:30316929 NCBI chr 5:127,505,646...127,523,016
Ensembl chr 5:127,505,614...127,523,089
JBrowse link
G Cpxm2 carboxypeptidase X (M14 family), member 2 decreases expression EXP oxybenzone results in decreased expression of CPXM2 mRNA CTD PMID:30316929 NCBI chr 1:204,048,785...204,161,090
Ensembl chr 1:204,048,785...204,087,001
JBrowse link
G Cstl1 cystatin-like 1 decreases expression EXP oxybenzone results in decreased expression of CSTL1 mRNA CTD PMID:30316929 NCBI chr 3:143,084,557...143,089,554
Ensembl chr 3:143,084,563...143,089,631
JBrowse link
G Cybrd1 cytochrome b reductase 1 increases expression EXP oxybenzone results in increased expression of CYBRD1 mRNA CTD PMID:30316929 NCBI chr 3:57,718,496...57,745,749
Ensembl chr 3:57,718,364...57,746,097
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases expression EXP oxybenzone results in increased expression of CYP19A1 mRNA CTD PMID:30599193 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Cyp21a1 cytochrome P450, family 21, subfamily a, polypeptide 1 decreases expression EXP oxybenzone results in decreased expression of CYP21A1 mRNA CTD PMID:30316929 NCBI chr20:4,486,213...4,489,358
Ensembl chr20:4,486,219...4,489,550
JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 decreases expression EXP oxybenzone results in decreased expression of CYP24A1 mRNA CTD PMID:30316929 NCBI chr 3:168,097,484...168,111,920
Ensembl chr 3:168,097,485...168,111,920
JBrowse link
G Cyp26c1 cytochrome P450, family 26, subfamily C, polypeptide 1 increases expression EXP oxybenzone results in increased expression of CYP26C1 mRNA CTD PMID:30316929 NCBI chr 1:256,369,410...256,380,649
Ensembl chr 1:256,370,850...256,378,335
JBrowse link
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 increases expression EXP oxybenzone results in increased expression of CYP27B1 mRNA CTD PMID:30316929 NCBI chr 7:70,333,150...70,340,006
Ensembl chr 7:70,335,061...70,340,005
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 decreases expression EXP oxybenzone results in decreased expression of CYP2B3 mRNA CTD PMID:30316929 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp2d3 cytochrome P450, family 2, subfamily d, polypeptide 3 increases expression EXP oxybenzone results in increased expression of CYP2D3 mRNA CTD PMID:30316929 NCBI chr 7:123,634,400...123,638,757
Ensembl chr 7:123,625,590...123,638,765
JBrowse link
G Cyp4a3 cytochrome P450, family 4, subfamily a, polypeptide 3 decreases expression EXP oxybenzone results in decreased expression of CYP4A3 mRNA CTD PMID:30316929 NCBI chr 5:134,468,666...134,484,851
Ensembl chr 5:134,469,270...134,484,839
JBrowse link
G Cyp4f18 cytochrome P450, family 4, subfamily f, polypeptide 18 increases expression EXP oxybenzone results in increased expression of CYP4F18 mRNA CTD PMID:30316929 NCBI chr16:19,501,680...19,528,935
Ensembl chr16:19,410,810...19,528,999
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 increases expression EXP oxybenzone results in increased expression of CYP7A1 mRNA CTD PMID:30316929 NCBI chr 5:19,358,734...19,368,431
Ensembl chr 5:19,358,734...19,368,431
JBrowse link
G Dap death-associated protein decreases expression EXP oxybenzone results in decreased expression of DAP mRNA CTD PMID:30316929 NCBI chr 2:84,275,884...84,328,998
Ensembl chr 2:84,275,884...84,328,998
JBrowse link
G Dapk3 death-associated protein kinase 3 increases expression EXP oxybenzone results in increased expression of DAPK3 mRNA CTD PMID:30316929 NCBI chr 7:11,392,436...11,400,855
Ensembl chr 7:11,392,437...11,400,805
JBrowse link
G Daxx death-domain associated protein increases expression EXP oxybenzone results in increased expression of DAXX mRNA CTD PMID:30316929 NCBI chr20:5,480,103...5,485,962
Ensembl chr20:5,480,103...5,485,926
JBrowse link
G Dedd death effector domain-containing increases expression EXP oxybenzone results in increased expression of DEDD mRNA CTD PMID:30316929 NCBI chr13:89,706,932...89,721,825
Ensembl chr13:89,718,066...89,721,454
JBrowse link
G Dffa DNA fragmentation factor subunit alpha increases expression EXP oxybenzone results in increased expression of DFFA mRNA CTD PMID:30316929 NCBI chr 5:165,922,893...165,935,822
Ensembl chr 5:165,922,915...165,935,821
JBrowse link
G Dhodh dihydroorotate dehydrogenase (quinone) increases expression EXP oxybenzone results in increased expression of DHODH mRNA CTD PMID:30316929 NCBI chr19:42,066,103...42,087,906
Ensembl chr19:42,066,351...42,082,012
JBrowse link
G Dlst dihydrolipoamide S-succinyltransferase increases expression EXP oxybenzone results in increased expression of DLST mRNA CTD PMID:30316929 NCBI chr 6:108,936,534...108,961,322
Ensembl chr 6:108,936,664...108,959,803
JBrowse link
G Dlx3 distal-less homeobox 3 affects expression EXP oxybenzone affects the expression of DLX3 mRNA CTD PMID:30316929 NCBI chr10:82,937,971...82,943,367
Ensembl chr10:82,937,971...82,943,348
JBrowse link
G Dnajc15 DnaJ heat shock protein family (Hsp40) member C15 decreases expression EXP oxybenzone results in decreased expression of DNAJC15 mRNA CTD PMID:30316929 NCBI chr15:59,990,131...60,056,710
Ensembl chr15:59,990,131...60,056,710
JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 increases expression EXP oxybenzone results in increased expression of ECHS1 mRNA CTD PMID:30316929 NCBI chr 1:212,570,213...212,579,040
Ensembl chr 1:212,570,195...212,579,057
JBrowse link
G Esr1 estrogen receptor 1 decreases expression
increases expression
multiple interactions
EXP
ISO
oxybenzone results in decreased expression of ESR1 mRNA; oxybenzone results in decreased expression of ESR1 protein
oxybenzone results in increased expression of ESR1 mRNA
oxybenzone binds to and results in increased activity of ESR1 protein
CTD PMID:15458797, PMID:16079615, PMID:30099065 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions
affects expression
decreases expression
ISO
EXP
oxybenzone binds to and results in increased activity of ESR2 protein
oxybenzone affects the expression of ESR2 protein
oxybenzone results in decreased expression of ESR2 mRNA
CTD PMID:16079615, PMID:30099065 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Esrra estrogen related receptor, alpha decreases expression EXP oxybenzone results in decreased expression of ESRRA mRNA CTD PMID:15458797 NCBI chr 1:222,168,729...222,178,842
Ensembl chr 1:222,168,730...222,178,725
JBrowse link
G Fabp4 fatty acid binding protein 4 multiple interactions ISO oxybenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FABP4 mRNA] CTD PMID:32407875 NCBI chr 2:93,792,666...93,797,267
Ensembl chr 2:93,792,601...93,797,305
JBrowse link
G Fam180a family with sequence similarity 180, member A decreases expression EXP oxybenzone results in decreased expression of FAM180A mRNA CTD PMID:30316929 NCBI chr 4:62,845,054...62,860,361
Ensembl chr 4:62,844,971...62,860,446
JBrowse link
G Fam71b family with sequence similarity 71, member B decreases expression EXP oxybenzone results in decreased expression of FAM71B mRNA CTD PMID:30316929 NCBI chr10:31,508,549...31,511,787
Ensembl chr10:31,508,512...31,511,788
JBrowse link
G Fam71f2 family with sequence similarity 71, member F2 decreases expression EXP oxybenzone results in decreased expression of FAM71F2 mRNA CTD PMID:30316929 NCBI chr 4:56,556,545...56,567,350
Ensembl chr 4:56,556,507...56,567,346
JBrowse link
G Flg filaggrin affects response to substance
multiple interactions
ISO FLG gene mutant form affects the susceptibility to oxybenzone
[FLG gene mutant form affects the susceptibility to oxybenzone] which results in decreased secretion of FSHB protein; [FLG gene mutant form affects the susceptibility to oxybenzone] which results in increased secretion of Estradiol; [FLG gene mutant form affects the susceptibility to oxybenzone] which results in increased secretion of Testosterone
CTD PMID:30245359 NCBI chr 2:193,565,401...193,574,297 JBrowse link
G Foxl2 forkhead box L2 increases expression
multiple interactions
EXP oxybenzone results in increased expression of FOXL2 mRNA
4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol inhibits the reaction [oxybenzone results in increased expression of FOXL2 mRNA]
CTD PMID:30599193 NCBI chr 8:107,194,492...107,197,644
Ensembl chr 8:107,194,551...107,195,675
JBrowse link
G Frzb frizzled-related protein decreases expression EXP oxybenzone results in decreased expression of FRZB mRNA CTD PMID:30316929 NCBI chr 3:67,635,604...67,668,772
Ensembl chr 3:67,635,607...67,668,772
JBrowse link
G Fshb follicle stimulating hormone subunit beta multiple interactions ISO [FLG gene mutant form affects the susceptibility to oxybenzone] which results in decreased secretion of FSHB protein CTD PMID:30245359 NCBI chr 3:98,088,321...98,092,131
Ensembl chr 3:98,088,324...98,092,131
JBrowse link
G Fst follistatin increases expression EXP oxybenzone results in increased expression of FST mRNA CTD PMID:30599193 NCBI chr 2:46,537,589...46,544,813
Ensembl chr 2:46,538,700...46,544,457
JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 affects expression EXP oxybenzone affects the expression of GPER1 protein CTD PMID:30099065 NCBI chr12:17,309,122...17,315,267
Ensembl chr12:17,309,834...17,311,112
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 affects expression EXP oxybenzone affects the expression of GRIN1 protein CTD PMID:31368502 NCBI chr 3:2,507,745...2,534,664
Ensembl chr 3:2,506,896...2,534,663
JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A affects expression EXP oxybenzone affects the expression of GRIN2A protein CTD PMID:31368502 NCBI chr10:5,707,806...6,123,568
Ensembl chr10:5,930,298...6,119,990
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 decreases expression EXP oxybenzone results in decreased expression of GSTA2 mRNA CTD PMID:30316929 NCBI chr 8:85,640,081...85,645,621 JBrowse link
G Gsta5 glutathione S-transferase alpha 5 decreases expression EXP oxybenzone results in decreased expression of GSTA5 mRNA CTD PMID:30316929 NCBI chr 8:85,553,659...85,564,914
Ensembl chr 8:85,553,734...85,565,179
JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression EXP oxybenzone results in increased expression of GSTM1 mRNA CTD PMID:30316929 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases expression EXP oxybenzone results in increased expression of GSTP1 mRNA CTD PMID:30316929 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Gstt2 glutathione S-transferase, theta 2 increases expression EXP oxybenzone results in increased expression of GSTT2 mRNA CTD PMID:30316929 NCBI chr20:13,760,810...13,764,481
Ensembl chr20:13,760,810...13,764,475
JBrowse link
G Gstt4 glutathione S-transferase, theta 4 decreases expression EXP oxybenzone results in decreased expression of GSTT4 mRNA CTD PMID:30316929 NCBI chr20:13,778,185...13,784,813
Ensembl chr20:13,778,178...13,784,827
JBrowse link
G H2ax H2A.X variant histone increases expression
multiple interactions
ISO oxybenzone results in increased expression of H2AX protein modified form
Fulvestrant inhibits the reaction [oxybenzone results in increased expression of H2AX protein modified form]
CTD PMID:31939680 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha decreases expression EXP oxybenzone results in decreased expression of HADHA mRNA CTD PMID:30316929 NCBI chr 6:27,589,840...27,628,921
Ensembl chr 6:27,589,657...27,629,175
JBrowse link
G Hdac1 histone deacetylase 1 increases expression EXP oxybenzone results in increased expression of HDAC1 protein CTD PMID:31368502 NCBI chr 5:147,716,664...147,743,723
Ensembl chr 5:147,716,664...147,743,723
JBrowse link
G Hdac2 histone deacetylase 2 increases expression EXP oxybenzone results in increased expression of HDAC2 protein CTD PMID:31368502 NCBI chr20:43,084,870...43,108,198
Ensembl chr20:43,084,870...43,108,198
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase increases expression ISO oxybenzone results in increased expression of HMGCR mRNA CTD PMID:32407875 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression ISO oxybenzone results in increased expression of HMGCS1 mRNA CTD PMID:32407875 NCBI chr 2:52,427,351...52,445,082
Ensembl chr 2:52,431,601...52,445,055
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 decreases expression EXP oxybenzone results in decreased expression of HMGCS2 mRNA CTD PMID:30316929 NCBI chr 2:200,452,623...200,480,785
Ensembl chr 2:200,452,624...200,479,423
JBrowse link
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 decreases expression EXP oxybenzone results in decreased expression of HSD17B10 mRNA CTD PMID:30316929 NCBI chr  X:21,696,796...21,699,241
Ensembl chr  X:21,696,772...21,699,241
JBrowse link
G Hsdl2 hydroxysteroid dehydrogenase like 2 decreases expression EXP oxybenzone results in decreased expression of HSDL2 mRNA CTD PMID:30316929 NCBI chr 5:76,812,881...76,848,853
Ensembl chr 5:76,812,931...76,848,101
JBrowse link
G Hykk hydroxylysine kinase increases expression EXP oxybenzone results in increased expression of HYKK mRNA CTD PMID:30316929 NCBI chr 8:59,507,975...59,531,745
Ensembl chr 8:59,507,990...59,529,366
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 decreases expression EXP oxybenzone results in decreased expression of IDH2 mRNA CTD PMID:30316929 NCBI chr 1:141,874,354...141,893,674
Ensembl chr 1:141,866,283...141,893,705
JBrowse link
G Idh3g isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma increases expression EXP oxybenzone results in increased expression of IDH3G mRNA CTD PMID:30316929 NCBI chr  X:156,999,803...157,008,735
Ensembl chr  X:156,999,826...157,008,733
JBrowse link
G Il19 interleukin 19 increases expression EXP oxybenzone results in increased expression of IL19 mRNA CTD PMID:30316929 NCBI chr13:47,663,592...47,677,869
Ensembl chr13:47,664,080...47,670,407
JBrowse link
G Ins2 insulin 2 multiple interactions ISO oxybenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ mRNA]; oxybenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ protein]; oxybenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FABP4 mRNA]; oxybenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of PPARG mRNA] CTD PMID:32407875 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Iqcf6 IQ motif containing F6 decreases expression EXP oxybenzone results in decreased expression of IQCF6 mRNA CTD PMID:30316929 NCBI chr 8:115,328,535...115,329,546
Ensembl chr 8:115,328,535...115,329,546
JBrowse link
G Krt18 keratin 18 decreases expression EXP oxybenzone results in decreased expression of KRT18 mRNA CTD PMID:30316929 NCBI chr 7:143,629,455...143,633,131
Ensembl chr 7:143,629,455...143,633,131
JBrowse link
G LOC100911804 apolipoprotein L3-like increases expression EXP oxybenzone results in increased expression of APOL2 mRNA CTD PMID:30316929 NCBI chr 7:118,979,230...118,986,699
Ensembl chr 7:118,979,608...118,983,984
JBrowse link
G Lsmem1 leucine-rich single-pass membrane protein 1 increases expression EXP oxybenzone results in increased expression of LSMEM1 mRNA CTD PMID:30316929 NCBI chr 6:60,114,077...60,124,297
Ensembl chr 6:60,114,103...60,124,274
JBrowse link
G Magel2 MAGE family member L2 increases expression EXP oxybenzone results in increased expression of MAGEL2 mRNA CTD PMID:30316929 NCBI chr 1:123,015,404...123,019,945
Ensembl chr 1:123,015,746...123,019,522
JBrowse link
G Mcc MCC regulator of WNT signaling pathway decreases expression EXP oxybenzone results in decreased expression of MCC mRNA CTD PMID:30316929 NCBI chr18:35,683,185...35,817,117
NCBI chr 1:12,006,663...12,128,849
Ensembl chr 1:12,006,660...12,128,845
Ensembl chr18:12,006,660...12,128,845
JBrowse link
G Medag mesenteric estrogen-dependent adipogenesis decreases expression EXP oxybenzone results in decreased expression of MEDAG mRNA CTD PMID:30316929 NCBI chr12:6,711,745...6,730,959
Ensembl chr12:6,711,747...6,740,714
JBrowse link
G Ncoa2 nuclear receptor coactivator 2 multiple interactions ISO oxybenzone promotes the reaction [NCOA2 protein binds to PPARG protein] CTD PMID:32407875 NCBI chr 5:5,466,544...5,696,540
Ensembl chr 5:5,616,483...5,694,598
JBrowse link
G Ndufa11 NADH:ubiquinone oxidoreductase subunit A11 decreases expression EXP oxybenzone results in decreased expression of NDUFA11 mRNA CTD PMID:30316929 NCBI chr 9:10,334,104...10,338,163
Ensembl chr 9:10,334,090...10,338,216
JBrowse link
G Ndufa3 NADH:ubiquinone oxidoreductase subunit A3 decreases expression EXP oxybenzone results in decreased expression of NDUFA3 mRNA CTD PMID:30316929 NCBI chr 1:64,172,462...64,175,174
Ensembl chr 1:64,172,540...64,175,099
JBrowse link
G Ndufa9 NADH:ubiquinone oxidoreductase subunit A9 increases expression EXP oxybenzone results in increased expression of NDUFA9 mRNA CTD PMID:30316929 NCBI chr 4:159,371,263...159,399,636
Ensembl chr 4:159,371,259...159,399,634
JBrowse link
G Ndufab1 NADH:ubiquinone oxidoreductase subunit AB1 increases expression EXP oxybenzone results in increased expression of NDUFAB1 mRNA CTD PMID:30316929 NCBI chr 1:192,044,209...192,057,644
Ensembl chr 1:192,044,216...192,057,612
JBrowse link
G Ndufb10 NADH:ubiquinone oxidoreductase subunit B10 increases expression EXP oxybenzone results in increased expression of NDUFB10 mRNA CTD PMID:30316929 NCBI chr10:14,090,128...14,092,289
Ensembl chr10:14,090,128...14,092,289
JBrowse link
G Ndufb7 NADH:ubiquinone oxidoreductase subunit B7 increases expression EXP oxybenzone results in increased expression of NDUFB7 mRNA CTD PMID:30316929 NCBI chr19:24,701,067...24,705,405
Ensembl chr19:24,701,049...24,705,405
JBrowse link
G Ndufs2 NADH:ubiquinone oxidoreductase core subunit S2 decreases expression EXP oxybenzone results in decreased expression of NDUFS2 mRNA CTD PMID:30316929 NCBI chr13:89,606,848...89,623,506
Ensembl chr13:89,606,840...89,619,398
JBrowse link
G Ndufv3 NADH:ubiquinone oxidoreductase subunit V3 affects expression EXP oxybenzone affects the expression of NDUFV3 mRNA CTD PMID:30316929 NCBI chr20:10,265,826...10,275,298
Ensembl chr20:10,265,806...10,275,304
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO oxybenzone results in increased activity of NR1I3 protein CTD PMID:28927721 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Nrf1 nuclear respiratory factor 1 increases expression EXP oxybenzone results in increased expression of NRF1 mRNA CTD PMID:30316929 NCBI chr 4:57,335,732...57,445,317
Ensembl chr 4:57,378,069...57,445,341
JBrowse link
G Ntn5 netrin 5 increases expression EXP oxybenzone results in increased expression of NTN5 mRNA CTD PMID:30316929 NCBI chr 1:101,668,354...101,678,117
Ensembl chr 1:101,669,086...101,677,596
JBrowse link
G Ogdh oxoglutarate dehydrogenase increases expression
decreases expression
EXP oxybenzone results in increased expression of OGDH mRNA
oxybenzone results in decreased expression of OGDH mRNA
CTD PMID:30316929 NCBI chr14:86,414,924...86,481,903
Ensembl chr14:86,414,949...86,613,327
JBrowse link
G Olr97 olfactory receptor 97 increases expression EXP oxybenzone results in increased expression of OLR97 mRNA CTD PMID:30316929 NCBI chr 1:168,500,223...168,502,357
Ensembl chr 1:168,500,304...168,501,212
JBrowse link
G Pdcd11 programmed cell death 11 increases expression EXP oxybenzone results in increased expression of PDCD11 mRNA CTD PMID:30316929 NCBI chr 1:266,866,931...266,908,042
Ensembl chr 1:266,866,931...266,908,042
JBrowse link
G Pdcd6ip programmed cell death 6 interacting protein decreases expression EXP oxybenzone results in decreased expression of PDCD6IP mRNA CTD PMID:30316929 NCBI chr 8:121,916,233...121,973,145
Ensembl chr 8:121,916,185...121,973,125
JBrowse link
G Pdcd7 programmed cell death 7 increases expression EXP oxybenzone results in increased expression of PDCD7 mRNA CTD PMID:30316929 NCBI chr 8:70,860,671...70,875,471
Ensembl chr 8:70,860,671...70,875,471
JBrowse link
G Pgr progesterone receptor multiple interactions
increases expression
ISO oxybenzone binds to and results in decreased activity of PGR protein
oxybenzone results in increased expression of PGR mRNA
CTD PMID:15537743, PMID:31939680 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Phf24 PHD finger protein 24 increases expression EXP oxybenzone results in increased expression of PHF24 mRNA CTD PMID:30316929 NCBI chr 5:58,359,744...58,387,446
Ensembl chr 5:58,359,498...58,383,070
JBrowse link
G Polm DNA polymerase mu decreases expression EXP oxybenzone results in decreased expression of POLM mRNA CTD PMID:30316929 NCBI chr14:86,069,378...86,079,327
Ensembl chr14:86,069,016...86,078,954
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases expression ISO oxybenzone results in increased expression of PPARA mRNA CTD PMID:32407875 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects binding
multiple interactions
increases expression
ISO oxybenzone binds to PPARG protein
oxybenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of PPARG mRNA]; oxybenzone promotes the reaction [NCOA2 protein binds to PPARG protein]
oxybenzone results in increased expression of PPARG mRNA
CTD PMID:32407875 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Prss37 serine protease 37 decreases expression EXP oxybenzone results in decreased expression of PRSS37 mRNA CTD PMID:30316929 NCBI chr 4:68,337,498...68,349,286
Ensembl chr 4:68,337,480...68,349,273
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases expression EXP oxybenzone results in increased expression of RELA protein CTD PMID:31368502 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Retn resistin decreases expression EXP oxybenzone results in decreased expression of RETN mRNA CTD PMID:30316929 NCBI chr12:2,201,909...2,203,649
Ensembl chr12:2,201,891...2,204,249
JBrowse link
G Sdha succinate dehydrogenase complex flavoprotein subunit A increases expression EXP oxybenzone results in increased expression of SDHA mRNA CTD PMID:30316929 NCBI chr 1:31,545,631...31,570,601
Ensembl chr 1:31,545,631...31,570,601
JBrowse link
G Serpinc1 serpin family C member 1 increases expression EXP oxybenzone results in increased expression of SERPINC1 mRNA CTD PMID:30316929 NCBI chr13:78,806,107...78,820,375
Ensembl chr13:78,805,347...78,833,192
JBrowse link
G Sh3glb1 SH3 domain -containing GRB2-like endophilin B1 increases expression EXP oxybenzone results in increased expression of SH3GLB1 mRNA CTD PMID:30316929 NCBI chr 2:250,709,812...250,744,216
Ensembl chr 2:250,709,439...250,744,196
JBrowse link
G Shank1 SH3 and multiple ankyrin repeat domains 1 increases expression EXP oxybenzone results in increased expression of SHANK1 mRNA CTD PMID:30316929 NCBI chr 1:100,297,137...100,344,377
Ensembl chr 1:100,297,152...100,344,377
JBrowse link
G Slc1a2 solute carrier family 1 member 2 affects expression EXP oxybenzone affects the expression of SLC1A2 protein CTD PMID:31368502 NCBI chr 3:92,518,679...92,665,731
Ensembl chr 3:92,640,752...92,665,644
JBrowse link
G Slc7a11 solute carrier family 7 member 11 affects expression EXP oxybenzone affects the expression of SLC7A11 protein CTD PMID:31368502 NCBI chr 2:139,453,774...139,528,479
Ensembl chr 2:139,453,774...139,528,162
JBrowse link
G Sox9 SRY-box transcription factor 9 multiple interactions
increases expression
EXP 4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol inhibits the reaction [oxybenzone results in increased expression of SOX9 mRNA] CTD PMID:30599193 NCBI chr10:101,288,528...101,294,030
Ensembl chr10:101,288,489...101,293,379
JBrowse link
G Sstr3 somatostatin receptor 3 increases expression EXP oxybenzone results in increased expression of SSTR3 mRNA CTD PMID:30316929 NCBI chr 7:119,760,881...119,768,082
Ensembl chr 7:119,760,888...119,768,082
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 decreases expression EXP oxybenzone results in decreased expression of SULT1A1 mRNA CTD PMID:30316929 NCBI chr 1:198,100,586...198,104,106
Ensembl chr 1:198,100,586...198,104,109
JBrowse link
G Tex46 testis expressed 46 decreases expression EXP oxybenzone results in decreased expression of TEX46 mRNA CTD PMID:30316929 NCBI chr 5:154,976,211...154,980,671
Ensembl chr 5:154,976,165...154,980,712
JBrowse link
G Tfam transcription factor A, mitochondrial increases expression EXP oxybenzone results in increased expression of TFAM mRNA CTD PMID:30316929 NCBI chr20:18,594,057...18,606,106
Ensembl chr20:18,594,037...18,606,151
JBrowse link
G Tff1 trefoil factor 1 multiple interactions
increases expression
ISO [oxybenzone co-treated with 2,4-dihydroxybenzophenone co-treated with octylmethoxycinnamate co-treated with enzacamene] results in increased expression of TFF1 mRNA; [oxybenzone co-treated with 2,4-dihydroxybenzophenone] results in increased expression of TFF1 mRNA
oxybenzone results in increased expression of TFF1 mRNA
CTD PMID:16183391 NCBI chr20:9,892,124...9,895,984
Ensembl chr20:9,892,124...9,895,984
JBrowse link
G Tmprss4 transmembrane serine protease 4 increases expression EXP oxybenzone results in increased expression of TMPRSS4 mRNA CTD PMID:30316929 NCBI chr 8:49,469,804...49,503,304
Ensembl chr 8:49,469,503...49,502,647
JBrowse link
G Tp53 tumor protein p53 decreases expression EXP oxybenzone results in decreased expression of TP53 mRNA CTD PMID:30316929 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 increases expression ISO oxybenzone results in increased expression of TP53BP1 protein CTD PMID:31939680 NCBI chr 3:113,160,030...113,259,701
Ensembl chr 3:113,160,000...113,231,790
JBrowse link
G Tspo translocator protein decreases expression EXP oxybenzone results in decreased expression of TSPO mRNA CTD PMID:30316929 NCBI chr 7:124,460,358...124,470,610
Ensembl chr 7:124,460,358...124,470,609
JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 decreases expression EXP oxybenzone results in decreased expression of UGT1A6 mRNA CTD PMID:30316929 NCBI chr 9:95,241,609...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt2a3 UDP glucuronosyltransferase family 2 member A3 decreases expression EXP oxybenzone results in decreased expression of UGT2A3 mRNA CTD PMID:30316929 NCBI chr14:22,251,507...22,267,899
Ensembl chr14:22,192,970...22,619,968
JBrowse link
G Upk1b uroplakin 1B decreases expression EXP oxybenzone results in decreased expression of UPK1B mRNA CTD PMID:30316929 NCBI chr11:64,522,008...64,553,234
Ensembl chr11:64,522,130...64,553,228
JBrowse link
G Uqcr11 ubiquinol-cytochrome c reductase, complex III subunit XI affects expression EXP oxybenzone affects the expression of UQCR11 mRNA CTD PMID:30316929 NCBI chr 7:12,171,146...12,175,838
Ensembl chr 7:12,171,185...12,175,835
JBrowse link
G Uqcrc1 ubiquinol-cytochrome c reductase core protein 1 increases expression EXP oxybenzone results in increased expression of UQCRC1 mRNA CTD PMID:30316929 NCBI chr 8:117,679,328...117,691,073
Ensembl chr 8:117,679,278...117,691,071
JBrowse link
G Uqcrfs1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 decreases expression EXP oxybenzone results in decreased expression of UQCRFS1 mRNA CTD PMID:30316929 NCBI chr17:35,677,984...35,682,262
Ensembl chr17:35,677,984...35,682,259
JBrowse link
G Uqcrq ubiquinol-cytochrome c reductase, complex III subunit VII increases expression EXP oxybenzone results in increased expression of UQCRQ mRNA CTD PMID:30316929 NCBI chr10:38,779,132...38,782,489
Ensembl chr10:38,779,132...38,782,419
JBrowse link
G V1ra14 vomeronasal 1 receptor A14 increases expression EXP oxybenzone results in increased expression of V1RA14 mRNA CTD PMID:30316929
G Vdac1 voltage-dependent anion channel 1 decreases expression EXP oxybenzone results in decreased expression of VDAC1 mRNA CTD PMID:30316929 NCBI chr10:37,724,915...37,752,827
Ensembl chr10:37,724,915...37,752,826
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      biological role 19734
        xenobiotic 18381
          oxybenzone 156
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19574
                        carbon atom 19563
                          organic molecular entity 19563
                            organic group 18495
                              organic divalent group 18488
                                organodiyl group 18488
                                  carbonyl group 18391
                                    carbonyl compound 18391
                                      ketone 16144
                                        aromatic ketone 11904
                                          benzophenones 1131
                                            hydroxybenzophenone 156
                                              oxybenzone 156
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.