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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:3-methylcholanthrene
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Accession:CHEBI:34342 term browser browse the term
Definition:A pentacyclic ortho- and peri-fused polycyclic arene consisting of a dihydrocyclopenta[ij]tetraphene ring system with a methyl substituent at the 3-position.
Synonyms:exact_synonym: 3-methyl-1,2-dihydrocyclopenta[ij]tetraphene
 related_synonym: 1,2-Dihydro-3-methylbenz(j)aceanthrylene;   20-MC;   20-Methylcholanthrene;   3-MC;   3-MCA;   3-methyl-1,2-dihydrobenzo[j]aceanthrylene;   Formula=C21H16;   InChI=1S/C21H16/c1-13-6-7-15-12-20-17-5-3-2-4-14(17)8-9-18(20)19-11-10-16(13)21(15)19/h2-9,12H,10-11H2,1H3;   InChIKey=PPQNQXQZIWHJRB-UHFFFAOYSA-N;   MC;   MCA;   Methylcholanthrene;   SMILES=Cc1ccc2cc3c(ccc4ccccc34)c3CCc1c23
 xref: Beilstein:1913890;   CAS:56-49-5;   KEGG:C14470;   LINCS:LSM-5711
 xref_mesh: MESH:D008748
 xref: PMID:11922910;   PMID:16359657;   PMID:24658119;   PMID:26076008;   PMID:7561049;   Reaxys:1913890;   Wikipedia:Methylcholanthrene


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3-methylcholanthrene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 decreases expression ISO Methylcholanthrene results in decreased expression of ABCA1 mRNA CTD PMID:20713471 NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A increases expression ISO Methylcholanthrene results in increased expression of ABCB1 mRNA; Methylcholanthrene results in increased expression of ABCB1A mRNA CTD PMID:11096091, PMID:27160211 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B increases expression
multiple interactions
ISO Methylcholanthrene results in increased expression of ABCB1B mRNA
Methylcholanthrene promotes the reaction [TRP53 protein binds to ABCB1B promoter]
CTD PMID:11096091, PMID:20713471 NCBI chr 4:22,225,123...22,307,577
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of ABCB4 mRNA CTD PMID:25926378 NCBI chr 4:22,133,984...22,192,687
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcb6 ATP binding cassette subfamily B member 6 increases expression ISO Methylcholanthrene results in increased expression of ABCB6 mRNA CTD PMID:22761424 NCBI chr 9:82,373,950...82,382,228
Ensembl chr 9:82,373,946...82,382,272
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression EXP Methylcholanthrene results in increased expression of ABCC3 mRNA CTD PMID:19118567 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 increases expression ISO Methylcholanthrene results in increased expression of ABCC4 mRNA; Methylcholanthrene results in increased expression of ABCC4 protein CTD PMID:20395535 NCBI chr15:103,695,415...103,927,980
Ensembl chr15:103,696,557...103,927,592
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions
affects response to substance
increases expression
ISO AHR protein affects the reaction [Methylcholanthrene results in increased expression of ABCG2 mRNA]; Methylcholanthrene promotes the reaction [AHR protein binds to ABCG2 5' UTR]
ABCG2 5' UTR affects the susceptibility to Methylcholanthrene
Methylcholanthrene results in increased expression of ABCG2; Methylcholanthrene results in increased expression of ABCG2 mRNA; Methylcholanthrene results in increased expression of ABCG2 mRNA alternative form; Methylcholanthrene results in increased expression of ABCG2 protein
CTD PMID:20804740, PMID:23081912 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Abi3bp ABI family member 3 binding protein decreases expression ISO Methylcholanthrene results in decreased expression of ABI3BP mRNA CTD PMID:20713471 NCBI chr11:46,206,932...46,422,791
Ensembl chr11:46,208,075...46,369,577
JBrowse link
G Acox2 acyl-CoA oxidase 2 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to ACOX2 promoter] CTD PMID:20348232 NCBI chr15:18,449,304...18,481,472
Ensembl chr15:18,451,144...18,481,470
JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to ACSL4 promoter] CTD PMID:20348232 NCBI chr  X:113,596,247...113,660,024
Ensembl chr  X:113,596,239...113,659,944
JBrowse link
G Acta1 actin, alpha 1, skeletal muscle decreases expression ISO Methylcholanthrene results in decreased expression of ACTA1 mRNA CTD PMID:29554273 NCBI chr19:56,674,072...56,677,084
Ensembl chr19:56,674,074...56,677,084
JBrowse link
G Acta2 actin alpha 2, smooth muscle decreases expression ISO Methylcholanthrene results in decreased expression of ACTA2 mRNA CTD PMID:20713471 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Adam8 ADAM metallopeptidase domain 8 increases expression ISO Methylcholanthrene results in increased expression of ADAM8 mRNA CTD PMID:20713471 NCBI chr 1:212,317,510...212,332,895
Ensembl chr 1:212,317,848...212,330,349
JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 decreases acetylation
increases methylation
multiple interactions
increases expression
EXP Methylcholanthrene results in decreased acetylation of ADAMTS1 promoter
Methylcholanthrene results in increased methylation of ADAMTS1 promoter
[alpha-naphthoflavone co-treated with Methylcholanthrene] results in decreased acetylation of ADAMTS1 promoter; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased acetylation of ADAMTS1 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased expression of ADAMTS1 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased methylation of ADAMTS1 promoter]
Methylcholanthrene results in increased expression of ADAMTS1 mRNA
CTD PMID:29094188 NCBI chr11:25,342,119...25,350,938
Ensembl chr11:25,342,126...25,350,974
JBrowse link
G Adamts12 ADAM metallopeptidase with thrombospondin type 1 motif, 12 decreases expression ISO Methylcholanthrene results in decreased expression of ADAMTS12 mRNA CTD PMID:20713471 NCBI chr 2:61,039,072...61,340,687
Ensembl chr 2:61,039,053...61,340,697
JBrowse link
G Adamts2 ADAM metallopeptidase with thrombospondin type 1 motif, 2 decreases expression ISO Methylcholanthrene results in decreased expression of ADAMTS2 mRNA CTD PMID:20713471 NCBI chr10:36,098,051...36,304,416
Ensembl chr10:36,098,051...36,304,409
JBrowse link
G Adamts4 ADAM metallopeptidase with thrombospondin type 1 motif, 4 increases expression ISO Methylcholanthrene results in increased expression of ADAMTS4 mRNA CTD PMID:20713471 NCBI chr13:89,622,996...89,632,485
Ensembl chr13:89,622,632...89,634,419
JBrowse link
G Adcy7 adenylate cyclase 7 increases expression ISO Methylcholanthrene results in increased expression of ADCY7 mRNA CTD PMID:20713471, PMID:29554273 NCBI chr19:19,702,307...19,762,973
Ensembl chr19:19,704,859...19,727,081
JBrowse link
G Adgrf1 adhesion G protein-coupled receptor F1 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to ADGRF1 promoter] CTD PMID:20348232 NCBI chr 9:20,343,730...20,378,686 JBrowse link
G Adgrg5 adhesion G protein-coupled receptor G5 multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of ADGRG5 mRNA; [Methylcholanthrene co-treated with Nanotubes, Carbon] results in increased expression of ADGRG5 mRNA CTD PMID:25926378 NCBI chr19:10,495,517...10,514,701
Ensembl chr19:10,495,517...10,513,349
JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide decreases expression ISO Methylcholanthrene results in decreased expression of ADH4 mRNA CTD PMID:27055685 NCBI chr 2:243,702,035...243,720,063
Ensembl chr 2:243,700,784...243,740,899
JBrowse link
G Adh6 alcohol dehydrogenase 6 (class V) decreases expression ISO Methylcholanthrene results in decreased expression of ADH6 mRNA CTD PMID:27055685 NCBI chr 2:243,656,568...243,687,857
Ensembl chr 2:243,550,627...243,687,857
JBrowse link
G Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide increases expression ISO Methylcholanthrene results in increased expression of ADH7 mRNA CTD PMID:20713471 NCBI chr 2:243,500,540...243,516,865
Ensembl chr 2:243,502,073...243,516,532
JBrowse link
G Adora2a adenosine A2a receptor multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ADORA2A mRNA CTD PMID:23519560 NCBI chr20:14,265,251...14,282,873
Ensembl chr20:14,265,252...14,282,873
JBrowse link
G Adora3 adenosine A3 receptor multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ADORA3 mRNA CTD PMID:23519560 NCBI chr 2:208,336,909...208,379,217
Ensembl chr 2:208,373,154...208,376,803
JBrowse link
G Adra2a adrenoceptor alpha 2A multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to ADRA2A promoter]
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ADRA2A mRNA
CTD PMID:20348232, PMID:23519560 NCBI chr 1:274,766,283...274,769,083
Ensembl chr 1:274,766,283...274,769,081
JBrowse link
G Aff1-as1 AFF1 antisense RNA 1 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to C4ORF36 promoter] CTD PMID:20348232 NCBI chr14:7,581,189...7,636,823
Ensembl chr14:7,581,189...7,636,822
JBrowse link
G Agr2 anterior gradient 2, protein disulphide isomerase family member multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to AGR2 promoter] CTD PMID:20348232 NCBI chr 6:55,465,782...55,487,087
Ensembl chr 6:55,465,782...55,487,714
JBrowse link
G Ahr aryl hydrocarbon receptor increases response to substance
increases expression
decreases expression
affects binding
multiple interactions
increases activity
increases localization
affects response to substance
increases degradation
affects localization
ISO
EXP
AHR protein results in increased susceptibility to Methylcholanthrene; AHR results in increased susceptibility to Methylcholanthrene
Methylcholanthrene results in increased expression of AHR mRNA
Methylcholanthrene results in decreased expression of AHR protein
Methylcholanthrene binds to AHR protein
[Genistein co-treated with Methylcholanthrene] affects the activity of AHR protein; AHR protein affects the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; AHR protein promotes the reaction [Methylcholanthrene results in increased expression of and results in increased activity of CYP1A1 protein]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to BAX promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to CASP9 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to CDK2 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to DNAJB6 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to HES1 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to ICAM1 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to IGF2 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to JAG1 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to SP1 promoter]]; Methylcholanthrene inhibits the reaction [Tetrachlorodibenzodioxin binds to AHR protein]; Methylcholanthrene promotes the reaction [AHR protein binds to BAX promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CASP9 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CDK2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to DNAJB6 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to HES1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ICAM1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to IGF2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to JAG1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SP1 promoter]
[Methylcholanthrene binds to and affects the localization of AHR protein] promotes the reaction [[AHR protein binds to CYP1A1 enhancer] which results in increased expression of CYP1A1 mRNA]; [Methylcholanthrene binds to and affects the localization of AHR protein] which results in increased expression of CYP1A1 mRNA; [Methylcholanthrene binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA; [Methylcholanthrene binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A2 mRNA; AHR affects the reaction [Methylcholanthrene results in increased activity of and results in increased expression of CYP1A1 protein]; AHR affects the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; AHR gene mutant form inhibits the reaction [Methylcholanthrene results in decreased expression of CYP3A11 mRNA]; AHR protein affects the reaction [Methylcholanthrene affects the expression of CYP1A1 mRNA]; AHR protein affects the reaction [Methylcholanthrene results in increased expression of FMO3 mRNA]; AHR protein promotes the reaction [Methylcholanthrene results in decreased expression of KNG1 mRNA]; AHR protein promotes the reaction [Methylcholanthrene results in decreased expression of KNG1 protein]; AHR protein promotes the reaction [Methylcholanthrene results in increased activity of CRYZ protein]; AHR protein promotes the reaction [Methylcholanthrene results in increased activity of XDH protein]; AHR protein promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; AHR protein promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; AHR protein promotes the reaction [Methylcholanthrene results in increased expression of CYP1A2 mRNA]; AHR protein promotes the reaction [Methylcholanthrene results in increased expression of CYP1A2 protein]; Capsaicin inhibits the reaction [Methylcholanthrene results in increased activity of and results in increased localization of AHR protein]; CTNNB1 protein affects the reaction [[Methylcholanthrene binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA]; Curcumin inhibits the reaction [Methylcholanthrene binds to AHR protein]; Cycloheximide promotes the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to CYP1A1 enhancer]]; Methylcholanthrene binds to and affects the localization of AHR protein; Methylcholanthrene binds to and results in increased activity of AHR protein; Methylcholanthrene inhibits the reaction [Tetrachlorodibenzodioxin binds to AHR protein]; Methylcholanthrene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of [SRC protein binds to AHR protein]]; Methylcholanthrene promotes the reaction [AHR protein binds to CYP1A1 enhancer]; Methylcholanthrene promotes the reaction [AHR protein binds to CYP1A1 promoter]; Methylcholanthrene results in increased activity of and results in increased localization of AHR protein; omeprazole sulfide inhibits the reaction [Methylcholanthrene results in increased activity of AHR protein]
Methylcholanthrene results in increased localization of AHR protein
AHR affects the susceptibility to Methylcholanthrene
Methylcholanthrene results in increased degradation of AHR protein
Methylcholanthrene results in increased expression of AHR protein
[AHR gene mutant form binds to ARNT protein] which results in decreased susceptibility to Methylcholanthrene; [chrysin co-treated with Methylcholanthrene] affects the activity of AHR protein; [Genistein co-treated with Methylcholanthrene] affects the activity of AHR protein; [Methylcholanthrene co-treated with pirinixic acid] results in increased expression of AHR protein; [Methylcholanthrene results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA; [Methylcholanthrene results in increased activity of AHR protein] which results in increased expression of IL1B mRNA; [Quercetin co-treated with Methylcholanthrene] affects the activity of AHR protein; AHR gene mutant form inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; AHR protein affects the reaction [Methylcholanthrene results in increased expression of ABCG2 mRNA]; AHR protein affects the reaction [Methylcholanthrene results in increased expression of MT2A mRNA]; AHR protein affects the susceptibility to [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; AHR protein affects the susceptibility to [Methylcholanthrene results in increased expression of CYP1A2 mRNA]; AHR protein promotes the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]; AHR protein promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; AHR protein promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased activity of AHR protein]; Methylcholanthrene binds to and results in increased activity of AHR protein; Methylcholanthrene binds to and results in increased activity of AHR protein polymorphism; Methylcholanthrene promotes the reaction [[AHR protein binds to ARNT protein] which binds to CYP1A1 enhancer]; Methylcholanthrene promotes the reaction [[AHR protein binds to ARNT protein] which results in increased expression of CYP1A1 mRNA]; Methylcholanthrene promotes the reaction [AHR protein binds to ABCG2 5' UTR]; Methylcholanthrene promotes the reaction [AHR protein binds to ACOX2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ACSL4 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ADGRF1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ADRA2A promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to AGR2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to AKAP13 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ANGPTL2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ANKRD13C promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ANKRD30B promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ARHGAP22 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ARHGAP35 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ARHGAP44 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ARL3 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ARMC12 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to BAMBI promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to BBX promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to BCL6 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to BPIFA2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to BRCA1 protein]; Methylcholanthrene promotes the reaction [AHR protein binds to BRWD1-AS2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to C16ORF74 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to C4ORF19 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to C4ORF36 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CA12 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CA8 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CACNA1B promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CALB2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CAST promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CCDC144NL promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CCDC57 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CCDC6 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CCN5 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CCNG2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CD55 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CEACAM3 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CENPL promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CEP70 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CFAP61 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CHPT1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CHRDL2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CILK1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CISD1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CLDN17 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CLK3 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CLPSL2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to COLCA1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to COX4I1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CRKL promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CTNNA1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CUEDC1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CYB5B promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CYP1A1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CYP1B1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CYP2A7 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to DEGS1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to DIAPH1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to DTNA promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to DUSP14 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to EHD3 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to EPS15 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ERCC6 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ESR1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to EXOSC9 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to FOXN1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to FOXN4 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to FREM2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to GDPD4 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to GPHB5 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to GREB1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to GRIK4 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to GSDMC promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to H2BC1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to H2BC21 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to HCRTR2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to HDAC11 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to HOXC11 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to HSBP1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to IDH2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to IER3 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to IGFBPL1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to INHBC promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to IRF2BPL promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ISOC2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ITPR1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to JPH1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to KATNAL2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to KCTD16 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to KCTD3 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to KIR2DL4 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to KLF9 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to KRT75 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to LGALS8 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to LGI1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to LIF promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to LIMA1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to LINC00173 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to LRP11 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to LSM5 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to LY6E promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to MAPKAP1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to MBNL1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to MED13L promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to MESP1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to MGST2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to MIDEAS promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to MLLT6 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to MLPH promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to MPI promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to MRTFB promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to MS4A7 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to MSMB promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to MYOF promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to MYOM2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to NBPF10 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to NBPF3 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to NDST1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to NELFCD promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to NFE2L2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to NMRAL1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to NXT2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to OSBPL10 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to OTUB2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to PAXBP1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to PCOLCE2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to PDCD4 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to PHACTR1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to PIGP promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to PIK3R1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to PLEKHA6 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to POGZ promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to POTEB promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to PPIAL4A promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to PRKAB1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to PRKAB2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to PRPS1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to PSG5 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to PSG9 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to PWWP3A promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RABL2A promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RALGAPA2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RANBP2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RBBP7 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RBM24 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RBMS2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RBSN promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RERG promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RFFL promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RGPD5 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RGPD6 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RGS3 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RHOBTB1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RHOH promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RPL11 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RTN3 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to RYR3 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to S100P promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SAMD12 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SCN3B promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SIK3 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SLC16A6 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SLC22A23 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SLC44A1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SLU7 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SMAP2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SMARCE1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SNAPIN promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SOCS7 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SOGA3 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SORL1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SOS1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SPON2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SPRED1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SPTLC2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SS18 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to STARD13 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to STAT5B promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SWSAP1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SYCP2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to SYT12 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to TBL1XR1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to TEAD4 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to THBS2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to THEM5 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to TIPARP promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to TMEM116 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to TMEM30A promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to TMEM45B promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to TMEM97 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to TMTC2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to TNK2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to TRERF1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to TRIM39 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to TRIM55 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to TRIM72 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to TRPV4 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to TTC3 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to UBE2E1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to UMODL1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to VEZT promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to VIPR1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to VSTM1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to VWCE promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to WBP1L promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to WDR26 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to WEE1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ZBTB4 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ZCCHC2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ZMAT3 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ZMIZ1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ZNF281 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ZNF552 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ZNF587 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ZNF695 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to ZNF710 promoter]; Methylcholanthrene promotes the reaction [Nicardipine results in increased activity of AHR protein]; Methylcholanthrene results in increased activity of and results in increased degradation of AHR protein; Nicardipine promotes the reaction [Methylcholanthrene results in increased activity of AHR protein]; omeprazole sulfide inhibits the reaction [Methylcholanthrene results in increased activity of AHR protein]; Resveratrol inhibits the reaction [Methylcholanthrene results in increased activity of AHR protein]
Methylcholanthrene affects the localization of AHR protein
CTD PMID:1650214, PMID:1654865, PMID:1658612, PMID:1846074, PMID:2154949, PMID:2833345, PMID:3005314, PMID:3024361, PMID:3040233, PMID:3402044, PMID:6301823, PMID:6322977, PMID:6749129, PMID:7140758, PMID:8163516, PMID:8163517, PMID:8937476, PMID:11158718, PMID:11243847, PMID:11285323, PMID:11339718, PMID:11549291, PMID:11768231, PMID:12117779, PMID:12490138, PMID:12700417, PMID:12825898, PMID:14993811, PMID:15297030, PMID:15585370, PMID:15860653, PMID:16109480, PMID:16137816, PMID:16359657, PMID:16489053, PMID:16829687, PMID:17069994, PMID:17880909, PMID:18022818, PMID:18259752, PMID:18835618, PMID:19286049, PMID:19853001, PMID:19951702, PMID:20067464, PMID:20171196, PMID:20348232, PMID:20540524, PMID:20570689, PMID:20570779, PMID:20804740, PMID:20881032, PMID:21250977, PMID:21292640, PMID:21498875, PMID:21666223, PMID:21756928, PMID:23273579, PMID:23712962, PMID:23846873, PMID:23994556, PMID:24486526, PMID:26006071, PMID:27644595, PMID:28887089, PMID:29094188 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Ahrr aryl-hydrocarbon receptor repressor multiple interactions
increases expression
ISO [Tetradecanoylphorbol Acetate co-treated with Methylcholanthrene] results in increased expression of AHRR mRNA
Methylcholanthrene results in increased expression of AHRR mRNA
CTD PMID:9887096, PMID:11423533, PMID:12655030, PMID:14672759 NCBI chr 1:31,603,297...31,698,329
Ensembl chr 1:31,603,297...31,698,329
JBrowse link
G Akap13 A-kinase anchoring protein 13 decreases expression
multiple interactions
ISO Methylcholanthrene results in decreased expression of AKAP13 mRNA
Methylcholanthrene promotes the reaction [AHR protein binds to AKAP13 promoter]
CTD PMID:20348232, PMID:20713471 NCBI chr 1:137,089,558...137,315,272
Ensembl chr 1:137,014,272...137,315,272
JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 increases expression ISO Methylcholanthrene results in increased expression of AKR1A1 mRNA CTD PMID:9973208 NCBI chr 5:135,482,068...135,498,693
Ensembl chr 5:135,482,068...135,498,822
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
decreases acetylation
increases expression
EXP alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased acetylation of AKT1 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of AKT1 mRNA] CTD PMID:29094188 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Alcam activated leukocyte cell adhesion molecule increases expression ISO Methylcholanthrene results in increased expression of ALCAM mRNA CTD PMID:20713471 NCBI chr11:50,780,735...50,985,083
Ensembl chr11:50,781,127...50,985,083
JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 increases expression ISO
EXP
Methylcholanthrene results in increased expression of ALDH3A1 mRNA CTD PMID:1416978, PMID:20713471, PMID:28601433 NCBI chr10:47,490,168...47,499,855
Ensembl chr10:47,490,153...47,499,876
JBrowse link
G Angptl2 angiopoietin-like 2 increases expression
multiple interactions
ISO Methylcholanthrene results in increased expression of ANGPTL2 mRNA
Methylcholanthrene promotes the reaction [AHR protein binds to ANGPTL2 promoter]
CTD PMID:20348232, PMID:20713471 NCBI chr 3:12,262,822...12,292,665
Ensembl chr 3:12,262,822...12,292,663
JBrowse link
G Ank2 ankyrin 2 decreases expression ISO Methylcholanthrene results in decreased expression of ANK2 mRNA CTD PMID:20713471 NCBI chr 2:231,224,643...231,522,655
Ensembl chr 2:231,226,949...231,648,122
JBrowse link
G Ankh ANKH inorganic pyrophosphate transport regulator increases expression ISO Methylcholanthrene results in increased expression of ANK mRNA CTD PMID:20713471 NCBI chr 2:80,131,563...80,256,948
Ensembl chr 2:80,131,563...80,256,954
JBrowse link
G Ankrd13c ankyrin repeat domain 13C multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to ANKRD13C promoter] CTD PMID:20348232 NCBI chr 2:264,785,379...264,833,283
Ensembl chr 2:264,786,242...264,833,283
JBrowse link
G Anln anillin, actin binding protein increases expression ISO Methylcholanthrene results in increased expression of ANLN mRNA CTD PMID:20713471 NCBI chr 8:23,336,455...23,397,122
Ensembl chr 8:23,337,621...23,390,773
JBrowse link
G Anxa8 annexin A8 increases expression ISO Methylcholanthrene results in increased expression of ANXA8 mRNA CTD PMID:20713471 NCBI chr16:10,417,174...10,432,388
Ensembl chr16:10,417,185...10,432,393
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression EXP Methylcholanthrene results in increased expression of APAF1 mRNA CTD PMID:23273579 NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192
JBrowse link
G Apcdd1 APC down-regulated 1 increases expression ISO Methylcholanthrene results in increased expression of APCDD1 mRNA CTD PMID:20713471 NCBI chr18:58,270,398...58,300,982
Ensembl chr18:58,270,410...58,301,002
JBrowse link
G Apoa4 apolipoprotein A4 decreases expression EXP Methylcholanthrene results in decreased expression of APOA4 mRNA CTD PMID:11328961 NCBI chr 8:50,536,983...50,539,371
Ensembl chr 8:50,537,009...50,539,376
JBrowse link
G Apoc1 apolipoprotein C1 decreases expression EXP Methylcholanthrene results in decreased expression of APOC1 mRNA CTD PMID:11328961 NCBI chr 1:80,606,638...80,609,921
Ensembl chr 1:80,606,638...80,609,921
JBrowse link
G Apod apolipoprotein D decreases expression ISO Methylcholanthrene results in decreased expression of APOD mRNA CTD PMID:20713471 NCBI chr11:72,705,204...72,726,263
Ensembl chr11:72,705,129...72,726,301
JBrowse link
G Aqp5 aquaporin 5 increases expression ISO
EXP
Methylcholanthrene results in increased expression of AQP5 mRNA CTD PMID:20713471, PMID:26372666 NCBI chr 7:141,249,044...141,252,576
Ensembl chr 7:141,249,044...141,252,578
JBrowse link
G Areg amphiregulin increases expression ISO
EXP
Methylcholanthrene results in increased expression of AREG mRNA CTD PMID:16257430, PMID:26372666 NCBI chr14:18,521,921...18,531,179
Ensembl chr14:18,521,930...18,531,179
JBrowse link
G Arhgap11a Rho GTPase activating protein 11A increases expression ISO Methylcholanthrene results in increased expression of ARHGAP11A mRNA CTD PMID:20713471 NCBI chr 3:105,281,827...105,298,108
Ensembl chr 3:105,281,827...105,298,108
JBrowse link
G Arhgap22 Rho GTPase activating protein 22 increases expression
multiple interactions
ISO Methylcholanthrene results in increased expression of ARHGAP22 mRNA
Methylcholanthrene promotes the reaction [AHR protein binds to ARHGAP22 promoter]
CTD PMID:20348232, PMID:20713471 NCBI chr16:9,454,269...9,613,508
Ensembl chr16:9,486,832...9,613,528
JBrowse link
G Arhgap35 Rho GTPase activating protein 35 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to ARHGAP35 promoter] CTD PMID:20348232 NCBI chr 1:78,456,409...78,573,374
Ensembl chr 1:78,456,409...78,573,374
JBrowse link
G Arhgap44 Rho GTPase activating protein 44 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to ARHGAP44 promoter] CTD PMID:20348232 NCBI chr10:51,501,547...51,669,546
Ensembl chr10:51,502,894...51,669,297
JBrowse link
G Arl3 ADP ribosylation factor like GTPase 3 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to ARL3 promoter] CTD PMID:20348232 NCBI chr 1:266,287,015...266,333,099
Ensembl chr 1:266,287,017...266,333,105
JBrowse link
G Arl6ip5 ADP-ribosylation factor like GTPase 6 interacting protein 5 increases expression ISO Methylcholanthrene results in increased expression of ARL6IP5 mRNA CTD PMID:20713471 NCBI chr 4:129,574,363...129,598,240
Ensembl chr 4:129,574,264...129,598,915
JBrowse link
G Armc12 armadillo repeat containing 12 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to ARMC12 promoter] CTD PMID:20348232 NCBI chr20:8,109,691...8,120,183
Ensembl chr20:8,109,635...8,120,180
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions
increases expression
increases localization
ISO
EXP
[AHR gene mutant form binds to ARNT protein] which results in decreased susceptibility to Methylcholanthrene; Methylcholanthrene promotes the reaction [[AHR protein binds to ARNT protein] which binds to CYP1A1 enhancer]; Methylcholanthrene promotes the reaction [[AHR protein binds to ARNT protein] which results in increased expression of CYP1A1 mRNA]; Methylcholanthrene promotes the reaction [ARNT protein binds to CCNG2 promoter]; Methylcholanthrene promotes the reaction [ARNT protein binds to CYP1A1 promoter]; Methylcholanthrene promotes the reaction [ARNT protein binds to CYP1B1 promoter]; Methylcholanthrene promotes the reaction [ARNT protein binds to ESR1 promoter]; Methylcholanthrene promotes the reaction [ARNT protein binds to FOXN4 promoter]; Methylcholanthrene promotes the reaction [ARNT protein binds to SORL1 promoter]
Methylcholanthrene results in increased expression of ARNT mRNA
Methylcholanthrene results in increased localization of ARNT protein
Cycloheximide promotes the reaction [Methylcholanthrene promotes the reaction [ARNT protein binds to CYP1A1 enhancer]]; Methylcholanthrene promotes the reaction [ARNT protein binds to CYP1A1 enhancer]
CTD PMID:11768231, PMID:19951702, PMID:20348232, PMID:20570689, PMID:21756928, PMID:23273579, PMID:24486526 NCBI chr 2:196,594,178...196,651,486
Ensembl chr 2:196,594,303...196,651,179
JBrowse link
G Arrb1 arrestin, beta 1 increases expression ISO Methylcholanthrene results in increased expression of ARRB1 mRNA CTD PMID:29554273 NCBI chr 1:164,502,099...164,573,947
Ensembl chr 1:164,502,389...164,593,139
JBrowse link
G Art3 ADP-ribosyltransferase 3 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ART3 mRNA CTD PMID:23519560 NCBI chr14:17,143,037...17,225,389
Ensembl chr14:17,143,040...17,225,389
JBrowse link
G Ascl1 achaete-scute family bHLH transcription factor 1 multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in increased expression of ASCL1 mRNA CTD PMID:25926378 NCBI chr 7:28,038,662...28,040,504
Ensembl chr 7:28,038,662...28,040,510
JBrowse link
G Asf1b anti-silencing function 1B histone chaperone increases expression ISO Methylcholanthrene results in increased expression of ASF1B mRNA CTD PMID:20713471 NCBI chr19:25,077,918...25,092,491
Ensembl chr19:25,077,918...25,092,491
JBrowse link
G Asic1 acid sensing ion channel subunit 1 increases expression ISO Methylcholanthrene results in increased expression of ASIC1 mRNA CTD PMID:20713471 NCBI chr 7:141,324,714...141,354,937
Ensembl chr 7:141,326,321...141,354,937
JBrowse link
G Aspm assembly factor for spindle microtubules increases expression ISO Methylcholanthrene results in increased expression of ASPM mRNA CTD PMID:20713471 NCBI chr13:56,546,021...56,591,793
Ensembl chr13:56,546,021...56,591,793
JBrowse link
G Aspn asporin decreases expression ISO Methylcholanthrene results in decreased expression of ASPN mRNA CTD PMID:20713471 NCBI chr17:14,655,958...14,681,355
Ensembl chr17:14,656,009...14,679,409
JBrowse link
G Atad2 ATPase family, AAA domain containing 2 increases expression ISO Methylcholanthrene results in increased expression of ATAD2 mRNA CTD PMID:20713471 NCBI chr 7:97,984,754...98,027,379
Ensembl chr 7:97,984,862...98,026,052
JBrowse link
G Atox1 antioxidant 1 copper chaperone increases expression EXP Methylcholanthrene results in increased expression of ATOX1 mRNA CTD PMID:23273579 NCBI chr10:40,790,850...40,805,886
Ensembl chr10:40,790,845...40,805,941
JBrowse link
G Atp6v1c2 ATPase H+ transporting V1 subunit C2 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of ATP6V1C2 mRNA CTD PMID:23519560 NCBI chr 6:42,585,452...42,632,289
Ensembl chr 6:42,585,934...42,630,983
JBrowse link
G Aurka aurora kinase A increases expression ISO Methylcholanthrene results in increased expression of AURKA mRNA CTD PMID:20713471 NCBI chr 3:170,364,177...170,380,278
Ensembl chr 3:170,364,181...170,378,210
JBrowse link
G Aurkb aurora kinase B increases expression ISO Methylcholanthrene results in increased expression of AURKB mRNA CTD PMID:20713471 NCBI chr10:55,625,860...55,632,399
Ensembl chr10:55,626,741...55,634,991
JBrowse link
G Bad BCL2-associated agonist of cell death increases expression EXP Methylcholanthrene results in increased expression of BAD mRNA CTD PMID:23273579 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Baiap2 BAR/IMD domain containing adaptor protein 2 increases expression ISO Methylcholanthrene results in increased expression of BAIAP2 mRNA CTD PMID:20713471 NCBI chr10:109,107,326...109,187,458
Ensembl chr10:109,107,389...109,187,115
JBrowse link
G Bambi BMP and activin membrane-bound inhibitor multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to BAMBI promoter] CTD PMID:20348232 NCBI chr17:56,905,419...56,909,675
Ensembl chr17:56,905,112...56,909,992
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
increases methylation
multiple interactions
EXP Methylcholanthrene results in increased expression of BAX mRNA
Methylcholanthrene results in increased methylation of BAX promoter
alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to BAX promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of BAX mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased methylation of BAX promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to BAX promoter]
CTD PMID:23273579, PMID:29094188 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bbx BBX high mobility group box domain containing multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to BBX promoter] CTD PMID:20348232 NCBI chr11:52,983,286...53,228,557
Ensembl chr11:53,081,025...53,228,716
JBrowse link
G Bcas3 BCAS3, microtubule associated cell migration factor decreases expression ISO Methylcholanthrene results in decreased expression of BCAS3 mRNA CTD PMID:22100608 NCBI chr10:72,756,548...73,271,851 JBrowse link
G Bcl10 BCL10, immune signaling adaptor multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in increased expression of BCL10 mRNA CTD PMID:25926378 NCBI chr 2:251,805,392...251,814,957
Ensembl chr 2:251,805,392...251,814,957
JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression EXP Methylcholanthrene results in increased expression of BCL2 mRNA CTD PMID:23273579 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl6 BCL6, transcription repressor increases expression
multiple interactions
ISO Methylcholanthrene results in increased expression of BCL6 mRNA
Methylcholanthrene promotes the reaction [AHR protein binds to BCL6 promoter]
CTD PMID:20348232, PMID:20713471, PMID:25926378 NCBI chr11:80,255,790...80,279,075
Ensembl chr11:80,255,790...80,279,075
JBrowse link
G Bdh2 3-hydroxybutyrate dehydrogenase 2 decreases expression ISO Methylcholanthrene results in decreased expression of BDH2 mRNA CTD PMID:20713471 NCBI chr 2:240,461,505...240,482,149
Ensembl chr 2:240,461,505...240,482,145
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 increases expression ISO Methylcholanthrene results in increased expression of BIRC3 mRNA CTD PMID:29554273 NCBI chr 8:6,048,590...6,076,828
Ensembl chr 8:6,048,969...6,076,598
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 increases expression ISO Methylcholanthrene results in increased expression of BIRC5 mRNA CTD PMID:20713471 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Bmf Bcl2 modifying factor increases expression ISO Methylcholanthrene results in increased expression of BMF mRNA CTD PMID:29554273 NCBI chr 3:110,303,515...110,324,125
Ensembl chr 3:110,306,067...110,324,084
JBrowse link
G Bmp15 bone morphogenetic protein 15 multiple interactions EXP [Methylcholanthrene co-treated with alpha-naphthoflavone] results in increased expression of BMP15 mRNA CTD PMID:29094188 NCBI chr  X:17,016,831...17,021,894
Ensembl chr  X:17,016,778...17,023,418
JBrowse link
G Bmp4 bone morphogenetic protein 4 decreases expression EXP Methylcholanthrene results in decreased expression of BMP4 mRNA CTD PMID:29094188 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740
JBrowse link
G Bpgm bisphosphoglycerate mutase increases expression ISO Methylcholanthrene results in increased expression of BPGM mRNA CTD PMID:20713471 NCBI chr 4:61,912,210...61,940,697
Ensembl chr 4:61,912,210...61,940,696
JBrowse link
G Bpifa2 BPI fold containing family A, member 2 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to BPIFA2 promoter] CTD PMID:20348232 NCBI chr 3:149,492,612...149,501,614
Ensembl chr 3:149,493,655...149,501,613
JBrowse link
G Brca1 BRCA1, DNA repair associated multiple interactions
increases expression
ISO Methylcholanthrene promotes the reaction [AHR protein binds to BRCA1 protein]
Methylcholanthrene results in increased expression of BRCA1 mRNA
CTD PMID:18259752, PMID:20713471 NCBI chr10:89,394,821...89,455,093
Ensembl chr10:89,394,803...89,454,681
JBrowse link
G Bri3bp Bri3 binding protein increases expression ISO Methylcholanthrene results in increased expression of BRI3BP mRNA CTD PMID:25926378 NCBI chr12:36,576,018...36,587,839
Ensembl chr12:36,576,020...36,587,839
JBrowse link
G Brip1 BRCA1 interacting protein C-terminal helicase 1 increases expression ISO Methylcholanthrene results in increased expression of BRIP1 mRNA CTD PMID:20713471 NCBI chr10:73,507,009...73,632,742
Ensembl chr10:73,507,100...73,629,581
JBrowse link
G Bst1 bone marrow stromal cell antigen 1 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of BST1 mRNA CTD PMID:23519560 NCBI chr14:71,798,218...71,814,540
Ensembl chr14:71,798,651...71,814,523
JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO Methylcholanthrene results in increased expression of BTG2 mRNA CTD PMID:22100608 NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982
JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase increases expression ISO Methylcholanthrene results in increased expression of BUB1 mRNA CTD PMID:20713471 NCBI chr 3:120,373,604...120,404,910
Ensembl chr 3:120,373,604...120,404,910
JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B increases expression ISO Methylcholanthrene results in increased expression of BUB1B mRNA CTD PMID:20713471 NCBI chr 3:110,367,949...110,420,471
Ensembl chr 3:110,367,939...110,420,458
JBrowse link
G C1qbp complement C1q binding protein multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of C1QBP mRNA CTD PMID:25926378 NCBI chr10:57,613,876...57,618,527
Ensembl chr10:57,613,879...57,618,527
JBrowse link
G C1s complement C1s increases expression ISO Methylcholanthrene results in increased expression of C1S2 mRNA CTD PMID:29554273 NCBI chr 4:157,143,592...157,155,592
Ensembl chr 4:157,143,592...157,155,609
JBrowse link
G C3 complement C3 increases expression ISO Methylcholanthrene results in increased expression of C3 mRNA CTD PMID:16257430, PMID:29554273 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G C4a complement C4A multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of C4A mRNA CTD PMID:23519560 NCBI chr20:2,651,599...2,678,183
Ensembl chr20:2,651,599...2,678,141
JBrowse link
G C4b complement C4B (Chido blood group) multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of C4B mRNA CTD PMID:23519560 NCBI chr20:4,302,344...4,316,752
Ensembl chr20:4,302,344...4,316,715
JBrowse link
G C6 complement C6 multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of C6 mRNA CTD PMID:25926378 NCBI chr 2:54,460,333...54,533,801
Ensembl chr 2:54,466,280...54,533,797
JBrowse link
G Ca12 carbonic anhydrase 12 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to CA12 promoter] CTD PMID:20348232 NCBI chr 8:72,405,770...72,461,425
Ensembl chr 8:72,405,748...72,460,240
JBrowse link
G Ca8 carbonic anhydrase 8 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to CA8 promoter] CTD PMID:20348232 NCBI chr 5:21,249,018...21,345,810
Ensembl chr 5:21,249,020...21,345,810
JBrowse link
G Cacna1b calcium voltage-gated channel subunit alpha1 B multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to CACNA1B promoter] CTD PMID:20348232 NCBI chr 3:1,740,026...1,924,959
Ensembl chr 3:1,740,024...1,924,827
JBrowse link
G Cacna1g calcium voltage-gated channel subunit alpha1 G multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CACNA1G mRNA CTD PMID:23519560 NCBI chr10:82,129,071...82,197,828
Ensembl chr10:82,129,506...82,197,848
JBrowse link
G Cadm1 cell adhesion molecule 1 multiple interactions EXP [Diethylnitrosamine co-treated with Methylcholanthrene] results in decreased expression of CADM1 protein; [Diethylnitrosamine co-treated with Methylcholanthrene] results in increased methylation of CADM1 gene CTD PMID:21163286 NCBI chr 8:51,858,906...52,200,591
Ensembl chr 8:52,127,399...52,189,722
JBrowse link
G Calb2 calbindin 2 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to CALB2 promoter] CTD PMID:20348232 NCBI chr19:41,482,743...41,509,617
Ensembl chr19:41,482,728...41,509,658
JBrowse link
G Calcrl calcitonin receptor like receptor decreases expression ISO Methylcholanthrene results in decreased expression of CALCRL mRNA CTD PMID:20713471 NCBI chr 3:71,747,938...71,845,487
Ensembl chr 3:71,747,956...71,845,232
JBrowse link
G Calm1 calmodulin 1 increases expression ISO Methylcholanthrene results in increased expression of CALM1 mRNA CTD PMID:20713471 NCBI chr 6:124,217,241...124,225,292
Ensembl chr 6:124,217,241...124,225,292
JBrowse link
G Calr calreticulin increases expression
multiple interactions
EXP Methylcholanthrene results in increased expression of CALR mRNA
alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of CALR mRNA]
CTD PMID:29094188 NCBI chr19:25,956,771...25,961,666
Ensembl chr19:25,956,771...25,961,666
JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CAMK2B mRNA CTD PMID:23519560 NCBI chr14:86,208,876...86,297,727
Ensembl chr14:86,208,901...86,297,652
JBrowse link
G Capg capping actin protein, gelsolin like increases expression ISO Methylcholanthrene results in increased expression of CAPG mRNA CTD PMID:20713471 NCBI chr 4:100,395,693...100,419,447
Ensembl chr 4:100,407,658...100,419,446
JBrowse link
G Cask calcium/calmodulin dependent serine protein kinase decreases expression ISO Methylcholanthrene results in decreased expression of CASK mRNA CTD PMID:20713471 NCBI chr  X:9,815,652...10,156,155
Ensembl chr  X:9,815,652...10,156,155
JBrowse link
G Casp3 caspase 3 increases expression
multiple interactions
ISO
EXP
Methylcholanthrene results in increased expression of CASP3 mRNA
Methylcholanthrene inhibits the reaction [3-amino-1,4-dimethyl-5H-pyrido(4,3-b)indole results in increased cleavage of and results in increased activity of CASP3 protein]
CTD PMID:11323195, PMID:11999409, PMID:20713471 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp9 caspase 9 increases expression
increases methylation
multiple interactions
EXP Methylcholanthrene results in increased expression of CASP9 mRNA
Methylcholanthrene results in increased methylation of CASP9 promoter
[alpha-naphthoflavone co-treated with Methylcholanthrene] results in decreased acetylation of CASP9 promoter; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to CASP9 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of CASP9 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased methylation of CASP9 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to CASP9 promoter]
CTD PMID:23273579, PMID:29094188 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cast calpastatin multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to CAST promoter] CTD PMID:20348232 NCBI chr 2:1,452,111...1,561,669
Ensembl chr 2:1,452,116...1,561,464
JBrowse link
G Ccdc57 coiled-coil domain containing 57 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to CCDC57 promoter] CTD PMID:20348232 NCBI chr10:110,046,012...110,110,775
Ensembl chr10:110,008,603...110,101,872
JBrowse link
G Ccdc6 coiled-coil domain containing 6 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to CCDC6 promoter] CTD PMID:20348232 NCBI chr20:19,729,005...19,825,219
Ensembl chr20:19,732,894...19,825,150
JBrowse link
G Ccl17 C-C motif chemokine ligand 17 decreases expression ISO Methylcholanthrene results in decreased expression of CCL17 mRNA CTD PMID:29554273 NCBI chr19:10,619,220...10,620,671
Ensembl chr19:10,619,220...10,620,671
JBrowse link
G Ccl19 C-C motif chemokine ligand 19 multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of CCL19 mRNA CTD PMID:25926378 NCBI chr 5:58,181,025...58,182,969
Ensembl chr 5:58,181,026...58,183,017
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO Methylcholanthrene results in increased expression of CCL2 mRNA CTD PMID:20713471, PMID:23397585 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 decreases expression ISO Methylcholanthrene results in decreased expression of CCL5 mRNA CTD PMID:20713471 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 increases expression ISO Methylcholanthrene results in increased expression of CCL7 mRNA CTD PMID:20713471 NCBI chr10:69,423,083...69,424,933
Ensembl chr10:69,423,086...69,424,979
JBrowse link
G Ccn1 cellular communication network factor 1 increases expression ISO Methylcholanthrene results in increased expression of CCN1 mRNA CTD PMID:20713471 NCBI chr 2:251,529,354...251,532,312
Ensembl chr 2:251,529,354...251,532,312
JBrowse link
G Ccn3 cellular communication network factor 3 increases expression ISO Methylcholanthrene results in increased expression of CCN3 mRNA CTD PMID:20713471 NCBI chr 7:94,375,134...94,382,154
Ensembl chr 7:94,375,020...94,383,024
JBrowse link
G Ccn4 cellular communication network factor 4 decreases expression ISO Methylcholanthrene results in decreased expression of CCN4 mRNA CTD PMID:20713471 NCBI chr 7:107,695,227...107,723,759
Ensembl chr 7:107,695,215...107,723,772
JBrowse link
G Ccn5 cellular communication network factor 5 increases expression
multiple interactions
ISO Methylcholanthrene results in increased expression of CCN5 mRNA
Methylcholanthrene promotes the reaction [AHR protein binds to CCN5 promoter]
CTD PMID:20348232, PMID:20713471 NCBI chr 3:160,207,969...160,219,316
Ensembl chr 3:160,207,913...160,219,331
JBrowse link
G Ccna2 cyclin A2 increases expression ISO Methylcholanthrene results in increased expression of CCNA2 mRNA CTD PMID:20713471 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214
JBrowse link
G Ccnb1 cyclin B1 increases expression ISO
EXP
Methylcholanthrene results in increased expression of CCNB1 mRNA CTD PMID:20713471, PMID:26372666 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Ccnb2 cyclin B2 increases expression
multiple interactions
ISO
EXP
Methylcholanthrene results in increased expression of CCNB2 mRNA
Methylcholanthrene inhibits the reaction [Estradiol results in increased expression of CCNB2 mRNA]
CTD PMID:20713471, PMID:26372666 NCBI chr 8:76,847,972...76,861,165 JBrowse link
G Ccnd1 cyclin D1 increases expression ISO Methylcholanthrene results in increased expression of CCND1 mRNA CTD PMID:20713471 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccne1 cyclin E1 increases expression ISO Methylcholanthrene results in increased expression of CCNE1 mRNA CTD PMID:29554273 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980
JBrowse link
G Ccne2 cyclin E2 increases expression ISO Methylcholanthrene results in increased expression of CCNE2 mRNA CTD PMID:20713471 NCBI chr 5:24,434,077...24,446,406
Ensembl chr 5:24,434,872...24,446,406
JBrowse link
G Ccng2 cyclin G2 multiple interactions
increases expression
ISO Methylcholanthrene promotes the reaction [AHR protein binds to CCNG2 promoter]; Methylcholanthrene promotes the reaction [ARNT protein binds to CCNG2 promoter]; Methylcholanthrene promotes the reaction [Methylcholanthrene results in increased expression of CCNG2 mRNA] CTD PMID:20348232 NCBI chr14:16,267,572...16,276,068
Ensembl chr14:16,267,573...16,276,068
JBrowse link
G Cd300e Cd300e molecule increases expression ISO Methylcholanthrene results in increased expression of CD300E mRNA CTD PMID:25926378 NCBI chr10:103,599,372...103,619,070
Ensembl chr10:103,599,103...103,619,083
JBrowse link
G Cd300lb CD300 molecule-like family member b increases expression ISO Methylcholanthrene results in increased expression of CD300LB mRNA CTD PMID:20713471 NCBI chr10:103,471,082...103,481,071
Ensembl chr10:103,467,725...103,481,153
JBrowse link
G Cd3d CD3d molecule decreases expression ISO Methylcholanthrene results in decreased expression of CD3D mRNA CTD PMID:25926378 NCBI chr 8:49,282,502...49,287,095
Ensembl chr 8:49,282,460...49,287,110
JBrowse link
G Cd44 CD44 molecule (Indian blood group) multiple interactions
increases expression
ISO [Butylated Hydroxytoluene co-treated with Methylcholanthrene] results in increased expression of CD44 mRNA alternative form
Methylcholanthrene results in increased expression of CD44 mRNA
CTD PMID:15390079, PMID:20713471 NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658
JBrowse link
G Cd48 Cd48 molecule increases expression ISO Methylcholanthrene results in increased expression of CD48 mRNA CTD PMID:20713471 NCBI chr13:90,116,601...90,140,371
Ensembl chr13:90,116,843...90,140,371
JBrowse link
G Cd5 Cd5 molecule increases expression ISO Methylcholanthrene results in increased expression of CD5 mRNA CTD PMID:25926378 NCBI chr 1:226,770,912...226,791,861
Ensembl chr 1:226,770,744...226,791,879
JBrowse link
G Cd55 CD55 molecule (Cromer blood group) multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to CD55 promoter] CTD PMID:20348232 NCBI chr13:47,125,156...47,153,557
Ensembl chr13:47,126,741...47,154,292
JBrowse link
G Cd59 CD59 molecule increases mutagenesis ISO Methylcholanthrene results in increased mutagenesis of CD59 protein CTD PMID:17045307 NCBI chr 3:94,010,481...94,028,660
Ensembl chr 3:94,010,475...94,028,621
JBrowse link
G Cd9 CD9 molecule multiple interactions
decreases expression
EXP alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased expression of CD9 mRNA] CTD PMID:29094188 NCBI chr 4:157,977,163...158,010,091
Ensembl chr 4:157,977,162...158,010,166
JBrowse link
G Cd96 CD96 molecule multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of CD96 mRNA CTD PMID:25926378 NCBI chr11:57,108,757...57,183,855
Ensembl chr11:57,108,956...57,183,270
JBrowse link
G Cda cytidine deaminase increases expression ISO Methylcholanthrene results in increased expression of CDA mRNA CTD PMID:20713471 NCBI chr 5:156,703,579...156,734,541
Ensembl chr 5:156,703,579...156,734,541
JBrowse link
G Cdc20 cell division cycle 20 increases expression ISO Methylcholanthrene results in increased expression of CDC20 mRNA CTD PMID:20713471 NCBI chr 5:137,260,728...137,264,931
Ensembl chr 5:137,260,739...137,265,015
JBrowse link
G Cdc25c cell division cycle 25C increases expression ISO Methylcholanthrene results in increased expression of CDC25C mRNA CTD PMID:20713471 NCBI chr18:27,528,768...27,550,316
Ensembl chr18:27,528,354...27,550,224
JBrowse link
G Cdc45 cell division cycle 45 increases expression ISO Methylcholanthrene results in increased expression of CDC45 mRNA CTD PMID:20713471 NCBI chr11:86,328,785...86,354,099
Ensembl chr11:86,329,012...86,358,453
JBrowse link
G Cdc6 cell division cycle 6 increases expression ISO Methylcholanthrene results in increased expression of CDC6 mRNA CTD PMID:20713471 NCBI chr10:86,819,477...86,833,301
Ensembl chr10:86,819,472...86,833,402
JBrowse link
G Cdca2 cell division cycle associated 2 increases expression ISO Methylcholanthrene results in increased expression of CDCA2 mRNA CTD PMID:20713471 NCBI chr15:44,365,396...44,411,601
Ensembl chr15:44,365,405...44,411,004
JBrowse link
G Cdca3 cell division cycle associated 3 increases expression ISO Methylcholanthrene results in increased expression of CDCA3 mRNA CTD PMID:20713471 NCBI chr 4:157,347,876...157,351,889
Ensembl chr 4:157,348,020...157,351,604
JBrowse link
G Cdca5 cell division cycle associated 5 increases expression ISO Methylcholanthrene results in increased expression of CDCA5 mRNA CTD PMID:20713471 NCBI chr 1:221,448,661...221,462,235
Ensembl chr 1:221,448,661...221,462,233
JBrowse link
G Cdca8 cell division cycle associated 8 increases expression ISO Methylcholanthrene results in increased expression of CDCA8 mRNA CTD PMID:20713471 NCBI chr 5:142,911,310...142,933,536
Ensembl chr 5:142,911,305...142,933,526
JBrowse link
G Cdh1 cadherin 1 decreases expression ISO Methylcholanthrene results in decreased expression of CDH1 protein CTD PMID:16619036 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Cdh13 cadherin 13 decreases expression ISO Methylcholanthrene results in decreased expression of CDH13 mRNA CTD PMID:20713471 NCBI chr19:50,848,793...51,971,618
Ensembl chr19:50,848,736...51,972,103
JBrowse link
G Cdh2 cadherin 2 multiple interactions EXP [Diethylnitrosamine co-treated with Methylcholanthrene] affects the expression of CDH2 protein; [Diethylnitrosamine co-treated with Methylcholanthrene] results in increased expression of CDH2 protein; [Diethylnitrosamine co-treated with Methylcholanthrene] results in increased methylation of CDH2 gene CTD PMID:21163286 NCBI chr18:8,146,971...8,366,037
Ensembl chr18:8,146,971...8,360,684
JBrowse link
G Cdh5 cadherin 5 multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of CDH5 mRNA CTD PMID:25926378 NCBI chr19:1,025,122...1,074,333
Ensembl chr19:1,023,683...1,074,365
JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression
multiple interactions
decreases methylation
increases expression
increases acetylation
ISO
EXP
Methylcholanthrene results in decreased expression of CDK2 protein
alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to CDK2 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased methylation of CDK2 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased acetylation of CDK2 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of CDK2 mRNA]; Methylcholanthrene promotes the reaction [AHR protein binds to CDK2 promoter]
CTD PMID:18022818, PMID:29094188 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
increases response to substance
multiple interactions
ISO Methylcholanthrene results in increased expression of CDKN1A mRNA
Methylcholanthrene results in increased expression of CDKN1A protein
CDKN1A protein results in increased susceptibility to Methylcholanthrene
Acetylcysteine inhibits the reaction [Methylcholanthrene results in increased expression of CDKN1A protein]; resveratrol inhibits the reaction [Methylcholanthrene results in increased expression of CDKN1A protein]
SB 203580 inhibits the reaction [Methylcholanthrene results in increased expression of CDKN1A mRNA]
CTD PMID:15882963, PMID:18022818 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions
increases response to substance
increases expression
ISO Acetylcysteine inhibits the reaction [Methylcholanthrene results in increased expression of CDKN1B protein]; resveratrol inhibits the reaction [Methylcholanthrene results in increased expression of CDKN1B protein]
CDKN1B protein results in increased susceptibility to Methylcholanthrene
CTD PMID:18022818 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cdkn2aipnl CDKN2A interacting protein N-terminal like increases expression ISO Methylcholanthrene results in increased expression of CDKN2AIPNL mRNA CTD PMID:20713471 NCBI chr10:37,422,647...37,432,082
Ensembl chr10:37,422,647...37,432,081
JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 increases expression ISO Methylcholanthrene results in increased expression of CDKN3 mRNA CTD PMID:20713471 NCBI chr15:23,553,171...23,564,538
Ensembl chr15:23,553,128...23,564,535
JBrowse link
G Cdt1 chromatin licensing and DNA replication factor 1 increases expression ISO Methylcholanthrene results in increased expression of CDT1 mRNA CTD PMID:20713471 NCBI chr19:55,381,565...55,386,511
Ensembl chr19:55,381,565...55,386,511
JBrowse link
G Ceacam19 CEA cell adhesion molecule 19 increases expression ISO Methylcholanthrene results in increased expression of CEACAM19 mRNA CTD PMID:25926378 NCBI chr 1:80,800,951...80,809,769
Ensembl chr 1:80,800,951...80,809,769
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CEBPA mRNA CTD PMID:23519560 NCBI chr 1:91,363,492...91,366,164
Ensembl chr 1:91,363,492...91,366,164
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions ISO [Capsaicin results in increased activity of CEBPB protein] inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; [Capsaicin results in increased activity of CEBPB protein] inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein] CTD PMID:21250977 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Cenpa centromere protein A increases expression ISO Methylcholanthrene results in increased expression of CENPA mRNA CTD PMID:20713471 NCBI chr 6:27,072,259...27,080,863
Ensembl chr 6:27,072,166...27,080,856
JBrowse link
G Cenpe centromere protein E increases expression ISO Methylcholanthrene results in increased expression of CENPE mRNA CTD PMID:20713471 NCBI chr 2:240,395,974...240,454,785
Ensembl chr 2:240,396,152...240,454,747
JBrowse link
G Cenpf centromere protein F increases expression ISO Methylcholanthrene results in increased expression of CENPF mRNA CTD PMID:20713471 NCBI chr13:108,132,499...108,178,609
Ensembl chr13:108,132,499...108,178,609
JBrowse link
G Cenph centromere protein H increases expression ISO Methylcholanthrene results in increased expression of CENPH mRNA CTD PMID:20713471 NCBI chr 2:30,766,637...30,780,123
Ensembl chr 2:30,766,590...30,780,121
JBrowse link
G Cenpi centromere protein I increases expression ISO Methylcholanthrene results in increased expression of CENPI mRNA CTD PMID:20713471 NCBI chr  X:105,147,045...105,198,798
Ensembl chr  X:105,147,153...105,198,797
JBrowse link
G Cenpk centromere protein K increases expression ISO Methylcholanthrene results in increased expression of CENPK mRNA CTD PMID:20713471 NCBI chr 2:34,312,766...34,373,945
Ensembl chr 2:34,312,766...34,335,776
JBrowse link
G Cenpl centromere protein L multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to CENPL promoter] CTD PMID:20348232 NCBI chr13:78,886,092...78,901,025
Ensembl chr13:78,886,163...78,901,420
JBrowse link
G Cenpu centromere protein U increases expression ISO Methylcholanthrene results in increased expression of CENPU mRNA CTD PMID:20713471 NCBI chr16:48,898,032...48,921,248
Ensembl chr16:48,897,982...48,921,242
JBrowse link
G Cep55 centrosomal protein 55 increases expression ISO Methylcholanthrene results in increased expression of CEP55 mRNA CTD PMID:20713471 NCBI chr 1:256,745,251...256,760,794
Ensembl chr 1:256,745,288...256,760,796
JBrowse link
G Cep70 centrosomal protein 70 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to CEP70 promoter] CTD PMID:20348232 NCBI chr 8:107,495,326...107,548,274
Ensembl chr 8:107,495,366...107,548,269
JBrowse link
G Ces1d carboxylesterase 1D decreases expression ISO Methylcholanthrene results in decreased expression of CES1 protein CTD PMID:10640517 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Ces2h carboxylesterase 2H decreases expression ISO Methylcholanthrene results in decreased expression of CES2 protein CTD PMID:10640517 NCBI chr19:37,052,555...37,067,176
Ensembl chr19:37,052,556...37,067,156
JBrowse link
G Ces3a carboxylesterase 3a increases expression ISO Methylcholanthrene results in increased expression of CES3 mRNA CTD PMID:20713471 NCBI chr19:37,070,705...37,079,411 JBrowse link
G Cfap61 cilia and flagella associated protein 61 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to CFAP61 promoter] CTD PMID:20348232 NCBI chr 3:140,141,768...140,421,840 JBrowse link
G Chd1l chromodomain helicase DNA binding protein 1-like increases expression ISO Methylcholanthrene results in increased expression of CHD1L mRNA CTD PMID:25926378 NCBI chr 2:199,714,044...199,792,270
Ensembl chr 2:199,716,713...199,771,896
JBrowse link
G Chd8 chromodomain helicase DNA binding protein 8 increases expression ISO Methylcholanthrene results in increased expression of CHD8 mRNA CTD PMID:25926378 NCBI chr15:28,612,932...28,672,574
Ensembl chr15:28,612,932...28,672,569
JBrowse link
G Chfr checkpoint with forkhead and ring finger domains multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of CHFR mRNA CTD PMID:25926378 NCBI chr12:52,562,594...52,596,162
Ensembl chr12:52,562,597...52,596,076
JBrowse link
G Chi3l1 chitinase 3 like 1 increases expression ISO Methylcholanthrene results in increased expression of CHI3L1 mRNA CTD PMID:20713471 NCBI chr13:51,022,844...51,030,797
Ensembl chr13:51,022,681...51,030,802
JBrowse link
G Chic1 cysteine-rich hydrophobic domain 1 increases expression ISO Methylcholanthrene results in increased expression of CHIC1 mRNA CTD PMID:20713471 NCBI chr  X:74,205,649...74,250,613
Ensembl chr  X:74,200,972...74,244,846
JBrowse link
G Chic2 cysteine-rich hydrophobic domain 2 multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of CHIC2 mRNA CTD PMID:25926378 NCBI chr14:35,683,657...35,718,005
Ensembl chr14:35,683,442...35,717,922
JBrowse link
G Chka choline kinase alpha increases expression EXP Methylcholanthrene results in increased expression of CHKA mRNA CTD PMID:7852267 NCBI chr 1:219,076,618...219,126,221
Ensembl chr 1:219,077,771...219,126,220
JBrowse link
G Chpt1 choline phosphotransferase 1 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to CHPT1 promoter] CTD PMID:20348232 NCBI chr 7:29,019,518...29,070,928
Ensembl chr 7:29,043,916...29,070,928
JBrowse link
G Chrdl2 chordin-like 2 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to CHRDL2 promoter] CTD PMID:20348232 NCBI chr 1:165,008,997...165,036,431
Ensembl chr 1:165,008,912...165,036,435
JBrowse link
G Chrnb1 cholinergic receptor nicotinic beta 1 subunit multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CHRNB1 mRNA CTD PMID:23519560 NCBI chr10:56,390,671...56,403,255
Ensembl chr10:56,390,671...56,403,188
JBrowse link
G Cilk1 ciliogenesis associated kinase 1 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to CILK1 promoter] CTD PMID:20348232 NCBI chr 8:85,413,998...85,473,374
Ensembl chr 8:85,413,537...85,472,694
JBrowse link
G Cisd1 CDGSH iron sulfur domain 1 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to CISD1 promoter] CTD PMID:20348232 NCBI chr20:18,493,538...18,506,923
Ensembl chr20:18,493,538...18,506,912
JBrowse link
G Cish cytokine inducible SH2-containing protein decreases expression ISO Methylcholanthrene results in decreased expression of CISH mRNA CTD PMID:22978700 NCBI chr 8:116,054,547...116,059,494
Ensembl chr 8:116,054,465...116,060,723
JBrowse link
G Ckap2 cytoskeleton associated protein 2 increases expression ISO Methylcholanthrene results in increased expression of CKAP2 mRNA CTD PMID:20713471 NCBI chr16:74,752,655...74,779,184
Ensembl chr16:74,752,655...74,779,184
JBrowse link
G Ckap2l cytoskeleton associated protein 2-like increases expression ISO Methylcholanthrene results in increased expression of CKAP2L mRNA CTD PMID:20713471 NCBI chr 3:121,796,221...121,822,352
Ensembl chr 3:121,796,238...121,822,436
JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 increases expression ISO Methylcholanthrene results in increased expression of CKS2 mRNA CTD PMID:20713471 NCBI chr17:13,587,664...13,593,423
Ensembl chr17:13,587,665...13,593,423
JBrowse link
G Cldn17 claudin 17 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to CLDN17 promoter] CTD PMID:20348232 NCBI chr11:28,477,184...28,478,360
Ensembl chr11:28,477,184...28,478,360
JBrowse link
G Clk3 CDC-like kinase 3 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to CLK3 promoter] CTD PMID:20348232 NCBI chr 8:62,528,135...62,543,550
Ensembl chr 8:62,528,225...62,542,622
JBrowse link
G Clpsl2 colipase-like 2 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to CLPSL2 promoter] CTD PMID:20348232 NCBI chr20:5,791,521...5,794,344
Ensembl chr20:5,791,449...5,794,344
JBrowse link
G Clspn claspin increases expression ISO Methylcholanthrene results in increased expression of CLSPN mRNA CTD PMID:20713471 NCBI chr 5:144,577,670...144,617,507
Ensembl chr 5:144,581,427...144,616,335
JBrowse link
G Cmip c-Maf-inducing protein multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of CMIP mRNA CTD PMID:25926378 NCBI chr19:49,792,273...50,000,535
Ensembl chr19:49,792,273...50,000,535
JBrowse link
G Cnst consortin, connexin sorting protein increases expression ISO Methylcholanthrene results in increased expression of CNST mRNA CTD PMID:23397585 NCBI chr13:97,838,325...97,915,131
Ensembl chr13:97,838,361...97,913,082
JBrowse link
G Cntn1 contactin 1 increases expression ISO Methylcholanthrene results in increased expression of CNTN1 mRNA CTD PMID:20713471 NCBI chr 7:133,290,606...133,588,314
Ensembl chr 7:133,400,485...133,586,677
JBrowse link
G Col11a1 collagen type XI alpha 1 chain decreases expression ISO Methylcholanthrene results in decreased expression of COL11A1 mRNA CTD PMID:20713471 NCBI chr 2:216,863,423...217,056,523
Ensembl chr 2:216,863,428...217,056,523
JBrowse link
G Col3a1 collagen type III alpha 1 chain decreases expression ISO Methylcholanthrene results in decreased expression of COL3A1 mRNA CTD PMID:20713471 NCBI chr 9:52,023,295...52,059,221
Ensembl chr 9:52,023,295...52,059,217
JBrowse link
G Col5a1 collagen type V alpha 1 chain decreases expression ISO Methylcholanthrene results in decreased expression of COL5A1 mRNA CTD PMID:20713471 NCBI chr 3:6,430,180...6,581,010
Ensembl chr 3:6,430,201...6,578,882
JBrowse link
G Col5a2 collagen type V alpha 2 chain decreases expression ISO Methylcholanthrene results in decreased expression of COL5A2 mRNA CTD PMID:20713471 NCBI chr 9:52,091,088...52,238,735
Ensembl chr 9:52,092,511...52,238,564
JBrowse link
G Col8a1 collagen type VIII alpha 1 chain decreases expression ISO Methylcholanthrene results in decreased expression of COL8A1 mRNA CTD PMID:20713471 NCBI chr11:44,877,690...45,006,203
Ensembl chr11:44,877,859...45,007,891
JBrowse link
G Cotl1 coactosin-like F-actin binding protein 1 decreases expression ISO Methylcholanthrene results in decreased expression of COTL1 mRNA CTD PMID:20713471 NCBI chr19:52,465,074...52,499,433
Ensembl chr19:52,465,087...52,499,433
JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4i1 multiple interactions
increases expression
ISO
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to COX4I1 promoter]
Methylcholanthrene results in increased expression of COX4I1 mRNA
CTD PMID:20348232, PMID:23273579 NCBI chr19:54,245,958...54,252,198
Ensembl chr19:54,245,950...54,252,225
JBrowse link
G Cpox coproporphyrinogen oxidase increases expression ISO Methylcholanthrene results in increased expression of CPOX mRNA CTD PMID:20713471 NCBI chr11:44,039,665...44,049,648
Ensembl chr11:44,039,669...44,049,648
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression EXP Methylcholanthrene results in increased expression of CPT1A protein CTD PMID:25786523 NCBI chr 1:218,568,157...218,629,679
Ensembl chr 1:218,569,510...218,629,678
JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases expression EXP Methylcholanthrene results in increased expression of CREB1 mRNA CTD PMID:23273579 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to CRKL promoter] CTD PMID:20348232 NCBI chr11:87,338,606...87,356,644
Ensembl chr11:87,778,312...87,815,043
JBrowse link
G Cryz crystallin zeta multiple interactions
increases expression
increases activity
ISO AHR protein promotes the reaction [Methylcholanthrene results in increased activity of CRYZ protein]; Copper inhibits the reaction [Methylcholanthrene results in increased activity of CRYZ protein]; Copper inhibits the reaction [Methylcholanthrene results in increased expression of CRYZ mRNA]; Lead inhibits the reaction [Methylcholanthrene results in increased expression of CRYZ mRNA]; Lead promotes the reaction [Methylcholanthrene results in increased activity of CRYZ protein]; Mercury promotes the reaction [Methylcholanthrene results in increased activity of CRYZ protein]; Mercury promotes the reaction [Methylcholanthrene results in increased expression of CRYZ mRNA] CTD PMID:15297030 NCBI chr 2:260,884,315...260,911,827
Ensembl chr 2:260,884,337...260,911,792
JBrowse link
G Csmd3 CUB and Sushi multiple domains 3 decreases expression ISO Methylcholanthrene results in decreased expression of CSMD3 mRNA CTD PMID:20713471 NCBI chr 7:86,695,703...88,072,106
Ensembl chr 7:86,673,993...88,071,472
JBrowse link
G Csn2 casein beta multiple interactions EXP Methylcholanthrene inhibits the reaction [8-prenylnaringenin results in increased expression of CSN2 mRNA] CTD PMID:26372666 NCBI chr14:21,972,274...21,979,511
Ensembl chr14:21,972,274...21,979,510
JBrowse link
G Csrp2 cysteine and glycine-rich protein 2 increases expression ISO Methylcholanthrene results in increased expression of CSRP2 mRNA CTD PMID:20713471 NCBI chr 7:53,630,675...53,649,309
Ensembl chr 7:53,630,621...53,649,310
JBrowse link
G Ctnna1 catenin alpha 1 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to CTNNA1 promoter] CTD PMID:20348232 NCBI chr18:27,923,229...28,055,972
Ensembl chr18:27,923,572...28,055,960
JBrowse link
G Ctnnb1 catenin beta 1 affects response to substance
increases response to substance
multiple interactions
ISO CTNNB1 protein affects the susceptibility to Methylcholanthrene
CTNNB1 protein results in increased susceptibility to Methylcholanthrene
CTNNB1 gene mutant form affects the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; CTNNB1 gene mutant form affects the reaction [Methylcholanthrene results in increased expression of CYP1A2 mRNA]; CTNNB1 protein affects the reaction [[Methylcholanthrene binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA]
CTD PMID:21498875, PMID:25174530 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Ctsd cathepsin D increases expression ISO Methylcholanthrene results in increased expression of CTSD mRNA CTD PMID:16257430 NCBI chr 1:215,541,570...215,553,446
Ensembl chr 1:215,541,542...215,553,451
JBrowse link
G Cuedc1 CUE domain containing 1 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to CUEDC1 promoter] CTD PMID:20348232 NCBI chr10:75,495,817...75,516,280
Ensembl chr10:75,495,817...75,516,304
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 increases expression ISO Methylcholanthrene results in increased expression of CX3CL1 mRNA CTD PMID:20713471 NCBI chr19:10,644,267...10,654,861
Ensembl chr19:10,644,244...10,653,800
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CXCL10 mRNA CTD PMID:23519560 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CXCL12 mRNA CTD PMID:23519560 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Cyb5b cytochrome b5 type B multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to CYB5B promoter] CTD PMID:20348232 NCBI chr19:39,357,814...39,391,680
Ensembl chr19:39,357,791...39,393,189
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
decreases response to substance
increases acetylation
increases methylation
increases expression
increases activity
increases metabolic processing
decreases activity
ISO
EXP
[Celsior co-treated with Methylcholanthrene] results in increased expression of CYP1A1 mRNA; [Dexamethasone co-treated with Mifepristone] promotes the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]; [Methylcholanthrene co-treated with Rifampin co-treated with Phenobarbital] results in increased expression of CYP1A1 mRNA; [Methylcholanthrene results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA; [NR3C1 protein co-treated with Dexamethasone] inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; [pirinixic acid co-treated with Methylcholanthrene] results in increased activity of CYP1A1 protein; [pirinixic acid co-treated with Methylcholanthrene] results in increased expression of CYP1A1 mRNA; AHR gene mutant form inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; AHR protein affects the susceptibility to [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; AHR protein promotes the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]; AHR protein promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; AHR protein promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Arsenic Trioxide inhibits the reaction [Methylcholanthrene results in increased expression of and results in increased activity of CYP1A1 protein]; Arsenic Trioxide inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Dexamethasone inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]; Dexamethasone inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Dexamethasone inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; Dexamethasone promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Glyburide inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Methylcholanthrene promotes the reaction [[AHR protein binds to ARNT protein] which binds to CYP1A1 enhancer]; Methylcholanthrene promotes the reaction [[AHR protein binds to ARNT protein] which results in increased expression of CYP1A1 mRNA]; Methylcholanthrene promotes the reaction [AHR protein binds to CYP1A1 promoter]; Methylcholanthrene promotes the reaction [ARNT protein binds to CYP1A1 promoter]; Methylcholanthrene promotes the reaction [ESR1 protein binds to CYP1A1 promoter]; Methylcholanthrene promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Methylcholanthrene promotes the reaction [Nicardipine results in increased activity of and results in increased expression of CYP1A1 protein]; Methylcholanthrene promotes the reaction [Nicardipine results in increased expression of CYP1A1 mRNA]; Methylcholanthrene promotes the reaction [pirinixic acid results in increased activity of CYP1A1 protein]; Methylcholanthrene promotes the reaction [pirinixic acid results in increased expression of CYP1A1 mRNA]; Methylcholanthrene results in increased expression of and results in increased activity of CYP1A1 protein; Nicardipine promotes the reaction [Methylcholanthrene results in increased activity of and results in increased expression of CYP1A1 protein]; Nicardipine promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; SPTLC1 protein inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; SPTLC1 protein mutant form inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]
CYP1A1 gene mutant form results in decreased susceptibility to Methylcholanthrene
Methylcholanthrene results in increased acetylation of CYP1A1 promoter
Methylcholanthrene results in increased methylation of CYP1A1 promoter
Methylcholanthrene results in increased expression of CYP1A1 mRNA; Methylcholanthrene results in increased expression of CYP1A1 protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Methylcholanthrene results in increased activity of and results in increased expression of CYP1A1 protein]; 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; [Capsaicin results in increased activity of CEBPB protein] inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; [Capsaicin results in increased activity of CEBPB protein] inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; [Methylcholanthrene binds to and affects the localization of AHR protein] promotes the reaction [[AHR protein binds to CYP1A1 enhancer] which results in increased expression of CYP1A1 mRNA]; [Methylcholanthrene binds to and affects the localization of AHR protein] which results in increased expression of CYP1A1 mRNA; [Methylcholanthrene binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA; AHR affects the reaction [Methylcholanthrene results in increased activity of and results in increased expression of CYP1A1 protein]; AHR affects the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; AHR protein affects the reaction [Methylcholanthrene affects the expression of CYP1A1 mRNA]; AHR protein promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; AHR protein promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; Arsenic inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]; Arsenic promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Arsenic promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; Cadmium inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]; Cadmium promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Cadmium promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; Capsaicin inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Capsaicin inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; Chromium inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]; Chromium promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Chromium promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; Copper inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]; Copper inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Copper inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; CTNNB1 gene mutant form affects the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; CTNNB1 protein affects the reaction [[Methylcholanthrene binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA]; Cycloheximide promotes the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to CYP1A1 enhancer]]; Cycloheximide promotes the reaction [Methylcholanthrene promotes the reaction [ARNT protein binds to CYP1A1 enhancer]]; Cycloheximide promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; CYP1A1 gene mutant form promotes the reaction [Methylcholanthrene results in increased expression of CYP1A2 mRNA]; CYP1A2 gene mutant form promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Lead inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]; Lead inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Mercury inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]; Mercury promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; Mercury promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; Methylcholanthrene promotes the reaction [AHR protein binds to CYP1A1 enhancer]; Methylcholanthrene promotes the reaction [AHR protein binds to CYP1A1 promoter]; Methylcholanthrene promotes the reaction [ARNT protein binds to CYP1A1 enhancer]; Methylcholanthrene results in increased activity of and results in increased expression of CYP1A1 protein; Methylcholanthrene results in increased expression of and results in increased activity of CYP1A1 protein; POR gene mutant form inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]
[[Methylcholanthrene results in increased expression of CYP1A1 protein] co-treated with [Methylcholanthrene results in increased expression of CYP1A2 protein]] results in decreased susceptibility to 3-amino-1,4-dimethyl-5H-pyrido(4,3-b)indole; [Methylcholanthrene co-treated with GNMT protein] results in increased expression of CYP1A1 mRNA; AHR protein affects the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; AHR protein promotes the reaction [Methylcholanthrene results in increased expression of and results in increased activity of CYP1A1 protein]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased acetylation of CYP1A1 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased methylation of CYP1A1 promoter]; Buthionine Sulfoximine inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]; Dexamethasone promotes the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]; Ethoxyquin inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]; herbimycin inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]; isoimperatorin promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; lead nitrate inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 protein]; Methylcholanthrene promotes the reaction [CYP1A1 protein results in increased oxidation of Toluene]; Methylcholanthrene promotes the reaction [Hexachlorocyclohexane results in increased expression of and results in increased activity of CYP1A1 protein]; Methylcholanthrene results in increased expression of and results in increased activity of CYP1A1 protein; protocatechuic acid inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A1 protein]; sodium arsenite inhibits the reaction [Methylcholanthrene results in increased expression of and results in increased activity of CYP1A1 protein]; sodium arsenite inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]
CYP1A1 protein results in increased metabolism of Methylcholanthrene
Methylcholanthrene results in increased activity of CYP1A1 promoter; Methylcholanthrene results in increased activity of CYP1A1 protein
Methylcholanthrene results in decreased activity of CYP1A1 protein
CTD PMID:1316759, PMID:1617633, PMID:1994898, PMID:2154949, PMID:3785172, PMID:4054433, PMID:6749129, PMID:7238523, PMID:7493548, PMID:7756127, PMID:7980650, PMID:8163516, PMID:8902619, PMID:9152597, PMID:9233375, PMID:9261130, PMID:9783729, PMID:9860486, PMID:9973208, PMID:10329507, PMID:10476907, PMID:10772642, PMID:10799337, PMID:10859152, PMID:10872632, PMID:10874126, PMID:11158718, PMID:11285323, PMID:11328961, PMID:11356909, PMID:11502733, PMID:11768231, PMID:11999409, PMID:12107646, PMID:12117779, PMID:12458634, PMID:12490138, PMID:12490585, PMID:12505372, PMID:12700417, PMID:14672759, PMID:14987951, PMID:14993811, PMID:15297030, PMID:15302093, PMID:15337587, PMID:15350676, PMID:15448115, PMID:15521013, PMID:15582647, PMID:15585370, PMID:15590115, PMID:15620718, PMID:15621696, PMID:15860653, PMID:15885734, PMID:15946133, PMID:16137816, PMID:16167840, PMID:16257430, PMID:16359657, PMID:16489053, PMID:16619036, PMID:16639589, PMID:16829687, PMID:16906435, PMID:16968971, PMID:17069994, PMID:17230597, PMID:17253728, PMID:18486174, PMID:18493746, PMID:18502397, PMID:19022236, PMID:19043309, PMID:19118567, PMID:19525444, PMID:19853001, PMID:19883719, PMID:19889059, PMID:19951702, PMID:20020105, PMID:20067464, PMID:20171196, PMID:20226384, PMID:20348232, PMID:20350595, PMID:20570689, PMID:20570779, PMID:20713471, PMID:20816883, PMID:20881032, PMID:21250977, PMID:21292640, PMID:21498875, PMID:21666223, PMID:21800402, PMID:22507882, PMID:22761424, PMID:23169610, PMID:23273579, PMID:23712962, PMID:24091107, PMID:24486526, PMID:24999631, PMID:25174530, PMID:26006071, PMID:26651356, PMID:27055685, PMID:27163632, PMID:27590069, PMID:27644595, PMID:28601433, PMID:28887089, PMID:29094188, PMID:29554273, PMID:30503582, PMID:30842367, PMID:32726451 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
increases response to substance
increases expression
increases activity
affects response to substance
ISO
EXP
[Celsior co-treated with Methylcholanthrene] results in increased expression of CYP1A2 mRNA; [Dexamethasone co-treated with Mifepristone] promotes the reaction [Methylcholanthrene results in increased activity of CYP1A2 protein]; AHR protein affects the susceptibility to [Methylcholanthrene results in increased expression of CYP1A2 mRNA]; Dehydroepiandrosterone inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A2 mRNA]; Dexamethasone inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A2 protein]; Dexamethasone promotes the reaction [Methylcholanthrene results in increased expression of CYP1A2 mRNA]; Methylcholanthrene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; Methylcholanthrene promotes the reaction [Nicardipine results in increased expression of CYP1A2 mRNA]; Mifepristone inhibits the reaction [Dexamethasone promotes the reaction [Methylcholanthrene results in increased expression of CYP1A2 mRNA]]; Nicardipine promotes the reaction [Methylcholanthrene results in increased expression of CYP1A2 mRNA]
CYP1A2 gene mutant form results in increased susceptibility to Methylcholanthrene
Methylcholanthrene results in increased expression of CYP1A2 mRNA; Methylcholanthrene results in increased expression of CYP1A2 protein
[Methylcholanthrene binds to and results in increased activity of AHR protein] which results in increased expression of CYP1A2 mRNA; AHR protein promotes the reaction [Methylcholanthrene results in increased expression of CYP1A2 mRNA]; AHR protein promotes the reaction [Methylcholanthrene results in increased expression of CYP1A2 protein]; CTNNB1 gene mutant form affects the reaction [Methylcholanthrene results in increased expression of CYP1A2 mRNA]; CYP1A1 gene mutant form promotes the reaction [Methylcholanthrene results in increased expression of CYP1A2 mRNA]; CYP1A2 gene mutant form promotes the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]
[[Methylcholanthrene results in increased expression of CYP1A1 protein] co-treated with [Methylcholanthrene results in increased expression of CYP1A2 protein]] results in decreased susceptibility to 3-amino-1,4-dimethyl-5H-pyrido(4,3-b)indole; [Methylcholanthrene results in increased activity of CYP1A2 protein] which results in increased oxidation of Uroporphyrinogens; lead nitrate inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A2 protein]; Methylcholanthrene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; Methylcholanthrene promotes the reaction [CYP1A2 protein results in increased oxidation of Toluene]; Methylcholanthrene promotes the reaction [Hexachlorocyclohexane results in increased expression of and results in increased activity of CYP1A2 protein]; Methylcholanthrene results in increased expression of and results in increased activity of CYP1A2 protein; protocatechuic acid inhibits the reaction [Methylcholanthrene results in increased activity of CYP1A2 protein]
CYP1A2 affects the susceptibility to Methylcholanthrene
CTD PMID:1617633, PMID:1994898, PMID:3785172, PMID:4054433, PMID:6749129, PMID:7238523, PMID:7493548, PMID:8120057, PMID:8902619, PMID:9152597, PMID:9233375, PMID:9744552, PMID:9783729, PMID:10476907, PMID:10772642, PMID:11285323, PMID:11328961, PMID:11356909, PMID:11549291, PMID:11999409, PMID:12107646, PMID:12117779, PMID:15144902, PMID:15302093, PMID:15448115, PMID:15590115, PMID:15769886, PMID:15946133, PMID:16167840, PMID:16639589, PMID:18486174, PMID:18493746, PMID:19022236, PMID:19118567, PMID:19135037, PMID:19497360, PMID:19525444, PMID:19679878, PMID:19772856, PMID:19951702, PMID:20067464, PMID:20171196, PMID:20226384, PMID:20595379, PMID:20881032, PMID:21498875, PMID:23169610, PMID:23273579, PMID:23603339, PMID:25174530, PMID:27644595, PMID:27917125, PMID:28174063, PMID:28887089, PMID:30503582, PMID:30842367, PMID:32726451 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions
increases expression
increases metabolic processing
increases chemical synthesis
ISO
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to CYP1B1 promoter]; Methylcholanthrene promotes the reaction [ARNT protein binds to CYP1B1 promoter]; Methylcholanthrene promotes the reaction [Methylcholanthrene results in increased expression of CYP1B1 mRNA]; Methylcholanthrene results in increased expression of and results in increased activity of CYP1B1 protein; Nicardipine promotes the reaction [Methylcholanthrene results in increased expression of CYP1B1 mRNA]
Methylcholanthrene results in increased expression of CYP1B1 mRNA; Methylcholanthrene results in increased expression of CYP1B1 protein
alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of CYP1B1 mRNA]
CYP1B1 protein results in increased metabolism of Methylcholanthrene
CYP1B1 protein results in increased chemical synthesis of Methylcholanthrene metabolite
CTD PMID:9783729, PMID:10402558, PMID:11323195, PMID:11328961, PMID:11502733, PMID:11922910, PMID:12107646, PMID:12117779, PMID:15582647, PMID:15885734, PMID:17253728, PMID:19889059, PMID:19951702, PMID:20067464, PMID:20093341, PMID:20348232, PMID:20350595, PMID:20570779, PMID:20713471, PMID:20881032, PMID:23169610, PMID:23273579, PMID:23712962, PMID:27163632, PMID:28601433, PMID:28887089, PMID:29554273 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 multiple interactions ISO Methylcholanthrene promotes the reaction [Calcitriol results in increased expression of CYP24A1 mRNA] CTD PMID:19244278 NCBI chr 3:168,097,484...168,111,920
Ensembl chr 3:168,097,485...168,111,920
JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 increases expression EXP Methylcholanthrene results in increased expression of CYP2A1 mRNA CTD PMID:11323195, PMID:19118567, PMID:22934830 NCBI chr 1:83,711,223...83,725,222
Ensembl chr 1:83,653,234...83,766,484
JBrowse link
G Cyp2a2 cytochrome P450, family 2, subfamily a, polypeptide 2 decreases expression
increases expression
EXP Methylcholanthrene results in decreased expression of CYP2A2 mRNA
Methylcholanthrene results in increased expression of CYP2A2 mRNA
CTD PMID:11328961, PMID:22934830, PMID:23273579 NCBI chr 1:83,744,229...83,766,490
Ensembl chr 1:83,653,234...83,766,484
JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 multiple interactions
increases expression
ISO
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to CYP2A7 promoter]
Methylcholanthrene results in increased expression of CYP2A5 mRNA
Methylcholanthrene results in increased expression of CYP2A3 mRNA
CTD PMID:12845369, PMID:20348232, PMID:22934830, PMID:30503582 NCBI chr 1:83,653,248...83,662,118
Ensembl chr 1:83,653,234...83,766,484
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions
decreases expression
affects expression
EXP
ISO
Methylcholanthrene promotes the reaction [Hexachlorocyclohexane results in increased expression of and results in increased activity of CYP2B1 protein]
Methylcholanthrene results in decreased expression of CYP2B10 mRNA
Methylcholanthrene affects the expression of CYP2B1 mRNA
CTD PMID:18486174, PMID:23273579, PMID:30503582 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 multiple interactions
affects expression
EXP Methylcholanthrene promotes the reaction [Hexachlorocyclohexane results in increased expression of and results in increased activity of CYP2B2 protein]
Methylcholanthrene affects the expression of CYP2B2 mRNA
CTD PMID:18486174, PMID:23273579 NCBI chr 1:83,103,925...83,119,578
Ensembl chr 1:83,103,925...83,119,193
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 decreases expression
increases expression
EXP
ISO
Methylcholanthrene results in decreased expression of CYP2B3 mRNA
Methylcholanthrene results in increased expression of CYP2B9 mRNA
CTD PMID:11328961, PMID:30503582 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 multiple interactions
increases expression
decreases expression
EXP Methylcholanthrene promotes the reaction [CYP2C11 protein results in increased oxidation of Toluene]
Methylcholanthrene results in increased expression of CYP2C11 mRNA
Methylcholanthrene results in decreased expression of CYP2C11 mRNA
CTD PMID:1994898, PMID:10476907, PMID:22978700, PMID:23273579 NCBI chr 1:257,676,172...258,004,428
Ensembl chr 1:257,970,345...258,004,434
JBrowse link
G Cyp2c13 cytochrome P450, family 2, subfamily c, polypeptide 13 increases expression EXP Methylcholanthrene results in increased expression of CYP2C13 protein CTD PMID:25786523 NCBI chr 1:258,796,624...258,877,023
Ensembl chr 1:258,796,622...258,877,045
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 increases expression ISO Methylcholanthrene results in increased expression of CYP2C29 mRNA CTD PMID:30503582 NCBI chr 1:147,236,480...147,307,988 JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 increases expression EXP Methylcholanthrene results in increased expression of CYP2D4 mRNA CTD PMID:11328961 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
decreases expression
increases expression
decreases activity
EXP
ISO
[Acetone co-treated with Methylcholanthrene] results in decreased expression of CYP2E1 mRNA; [Acetone co-treated with Methylcholanthrene] results in decreased expression of CYP2E1 protein; [Acetone co-treated with Methylcholanthrene] results in increased activity of CYP2E1 protein; [Acetone co-treated with Methylcholanthrene] results in increased expression of CYP2E1 protein; [Methylcholanthrene results in decreased expression of CYP2E1 protein] which affects the metabolism of Benzene; [protocatechuic acid co-treated with Methylcholanthrene] results in decreased activity of CYP2E1 protein; [pyridine co-treated with Methylcholanthrene] results in decreased expression of CYP2E1 mRNA; [pyridine co-treated with Methylcholanthrene] results in decreased expression of CYP2E1 protein; [pyridine co-treated with Methylcholanthrene] results in increased activity of CYP2E1 protein; [pyridine co-treated with Methylcholanthrene] results in increased expression of CYP2E1 protein; Methylcholanthrene promotes the reaction [CYP2E1 protein results in increased oxidation of Toluene]
Methylcholanthrene results in decreased expression of CYP2E1 mRNA
Methylcholanthrene results in increased expression of CYP2E1 mRNA; Methylcholanthrene results in increased expression of CYP2E1 protein
Methylcholanthrene results in decreased expression of CYP2E1 mRNA; Methylcholanthrene results in decreased expression of CYP2E1 protein
Methylcholanthrene results in decreased activity of CYP2E1 protein
CTD PMID:1994898, PMID:3113478, PMID:7493548, PMID:8734847, PMID:9118891, PMID:10476907, PMID:15302093, PMID:19889059, PMID:23273579, PMID:28673560, PMID:30503582 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp2s1 cytochrome P450, family 2, subfamily s, polypeptide 1 increases expression EXP Methylcholanthrene results in increased expression of CYP2S1 mRNA CTD PMID:19883719 NCBI chr 1:82,595,211...82,610,350
Ensembl chr 1:82,595,211...82,610,350
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
increases expression
EXP Dactinomycin inhibits the reaction [Methylcholanthrene results in increased expression of CYP3A2 mRNA] CTD PMID:11181506 NCBI chr12:11,641,500...11,677,818
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases expression EXP Methylcholanthrene results in increased expression of CYP3A23-3A1 mRNA CTD PMID:23273579 NCBI chr12:11,053,888...11,082,742
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp4a3 cytochrome P450, family 4, subfamily a, polypeptide 3 increases expression EXP Methylcholanthrene results in increased expression of CYP4A3 mRNA CTD PMID:19889059 NCBI chr 5:134,468,666...134,484,851
Ensembl chr 5:134,469,270...134,484,839
JBrowse link
G Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 increases expression EXP Methylcholanthrene results in increased expression of CYP4B1 mRNA CTD PMID:23273579 NCBI chr 5:134,508,728...134,526,103
Ensembl chr 5:134,508,730...134,526,089
JBrowse link
G Cyp4f4 cytochrome P450, family 4, subfamily f, polypeptide 4 increases expression EXP Methylcholanthrene results in increased expression of CYP4F4 mRNA CTD PMID:19889059 NCBI chr 7:14,891,062...14,907,250
Ensembl chr 7:14,891,001...14,907,305
JBrowse link
G Cyp4f5 cytochrome P450, family 4, subfamily f, polypeptide 5 increases expression EXP Methylcholanthrene results in increased expression of CYP4F5 mRNA CTD PMID:19889059 NCBI chr 7:14,559,806...14,574,345
Ensembl chr 7:14,529,482...14,574,361
JBrowse link
G Cyp4f6 cytochrome P450, family 4, subfamily f, polypeptide 6 decreases expression EXP Methylcholanthrene results in decreased expression of CYP4F6 mRNA CTD PMID:11328961 NCBI chr 7:15,198,950...15,225,547
Ensembl chr 7:15,198,940...15,225,410
JBrowse link
G Dab2 DAB adaptor protein 2 increases expression ISO Methylcholanthrene results in increased expression of DAB2 mRNA CTD PMID:20713471 NCBI chr 2:55,747,353...55,768,848
Ensembl chr 2:55,747,318...55,768,270
JBrowse link
G Dact1 dishevelled-binding antagonist of beta-catenin 1 decreases expression ISO Methylcholanthrene results in decreased expression of DACT1 mRNA CTD PMID:20713471 NCBI chr 6:93,740,440...93,751,003
Ensembl chr 6:93,740,586...93,749,809
JBrowse link
G Dapk1 death associated protein kinase 1 multiple interactions EXP
ISO
[Diethylnitrosamine co-treated with Methylcholanthrene] results in decreased expression of DAPK1 protein; [Diethylnitrosamine co-treated with Methylcholanthrene] results in increased methylation of DAPK1 promoter
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of DAPK1 mRNA
CTD PMID:20970405, PMID:23519560 NCBI chr17:4,297,038...4,454,941
Ensembl chr17:4,297,224...4,454,778
JBrowse link
G Dapk2 death-associated protein kinase 2 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of DAPK2 mRNA CTD PMID:23519560 NCBI chr 8:71,822,107...71,941,941
Ensembl chr 8:71,822,129...71,941,910
JBrowse link
G Dbn1 drebrin 1 decreases expression ISO Methylcholanthrene results in decreased expression of DBN1 mRNA CTD PMID:20713471 NCBI chr17:9,679,511...9,693,878
Ensembl chr17:9,679,628...9,693,820
JBrowse link
G Dck deoxycytidine kinase increases expression ISO Methylcholanthrene results in increased expression of DCK mRNA CTD PMID:20713471 NCBI chr14:20,935,442...20,952,939
Ensembl chr14:20,935,369...20,953,095
JBrowse link
G Dclk1 doublecortin-like kinase 1 decreases expression ISO Methylcholanthrene results in decreased expression of DCLK1 mRNA CTD PMID:20713471 NCBI chr 2:144,646,255...144,939,389
Ensembl chr 2:144,646,308...144,936,927
JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 multiple interactions
increases expression
EXP alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of DDR2 mRNA] CTD PMID:29094188 NCBI chr13:88,311,639...88,436,561
Ensembl chr13:88,317,145...88,436,789
JBrowse link
G Ddx17 DEAD-box helicase 17 increases expression ISO Methylcholanthrene results in increased expression of DDX17 mRNA CTD PMID:25926378 NCBI chr 7:120,761,843...120,765,012
Ensembl chr 7:120,761,826...120,780,641
JBrowse link
G Ddx5 DEAD-box helicase 5 multiple interactions
increases expression
EXP alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of DDX5 mRNA] CTD PMID:29094188 NCBI chr10:94,979,759...94,988,461
Ensembl chr10:94,980,928...94,988,461
JBrowse link
G Degs1 delta(4)-desaturase, sphingolipid 1 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to DEGS1 promoter] CTD PMID:20348232 NCBI chr13:100,665,265...100,672,731
Ensembl chr13:100,666,075...100,672,731
JBrowse link
G Depdc1 DEP domain containing 1 increases expression ISO Methylcholanthrene results in increased expression of DEPDC1A mRNA CTD PMID:20713471 NCBI chr 2:264,704,738...264,738,265
Ensembl chr 2:264,704,769...264,738,257
JBrowse link
G Depdc1b DEP domain containing 1B increases expression ISO Methylcholanthrene results in increased expression of DEPDC1B mRNA CTD PMID:20713471 NCBI chr 2:39,980,796...40,069,982
Ensembl chr 2:40,000,313...40,069,975
JBrowse link
G Deptor DEP domain containing MTOR-interacting protein decreases expression ISO Methylcholanthrene results in decreased expression of DEPTOR mRNA CTD PMID:20713471 NCBI chr 7:94,795,161...95,000,750
Ensembl chr 7:94,795,214...94,995,809
JBrowse link
G Dhfr dihydrofolate reductase increases expression ISO Methylcholanthrene results in increased expression of DHFR mRNA CTD PMID:20713471 NCBI chr 2:21,931,887...21,958,927
Ensembl chr 2:21,931,493...21,962,453
JBrowse link
G Diaph1 diaphanous-related formin 1 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to DIAPH1 promoter] CTD PMID:20348232 NCBI chr18:30,972,907...31,071,371
Ensembl chr18:30,972,907...31,071,371
JBrowse link
G Dlgap5 DLG associated protein 5 increases expression ISO Methylcholanthrene results in increased expression of DLGAP5 mRNA CTD PMID:20713471 NCBI chr15:24,167,484...24,199,417
Ensembl chr15:24,167,486...24,199,341
JBrowse link
G Dll1 delta like canonical Notch ligand 1 increases expression
multiple interactions
EXP Methylcholanthrene results in increased expression of DLL1 mRNA
alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of DLL1 mRNA]
CTD PMID:29094188 NCBI chr 1:57,318,621...57,326,732
Ensembl chr 1:57,318,708...57,327,379
JBrowse link
G Dmp1 dentin matrix acidic phosphoprotein 1 increases expression ISO Methylcholanthrene results in increased expression of DMP1 mRNA CTD PMID:20713471 NCBI chr14:6,889,851...6,923,961
Ensembl chr14:6,889,856...6,900,733
JBrowse link
G Dnajb6 DnaJ heat shock protein family (Hsp40) member B6 multiple interactions
increases acetylation
increases methylation
increases expression
EXP alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to DNAJB6 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased acetylation of DNAJB6 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of DNAJB6 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased methylation of DNAJB6 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to DNAJB6 promoter] CTD PMID:29094188 NCBI chr 4:2,711,329...2,774,969
Ensembl chr 4:2,711,385...2,774,890
JBrowse link
G Dnajc9 DnaJ heat shock protein family (Hsp40) member C9 increases expression ISO Methylcholanthrene results in increased expression of DNAJC9 mRNA CTD PMID:20713471 NCBI chr15:4,356,512...4,360,788
Ensembl chr15:4,356,261...4,360,564
JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions EXP [Diethylnitrosamine co-treated with Methylcholanthrene] affects the expression of and affects the localization of DNMT1 protein CTD PMID:21163286 NCBI chr 8:21,922,515...21,968,495
Ensembl chr 8:21,922,515...21,968,495
JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha multiple interactions EXP [Diethylnitrosamine co-treated with Methylcholanthrene] affects the expression of and affects the localization of DNMT3A protein CTD PMID:21163286 NCBI chr 6:28,205,375...28,346,052
Ensembl chr 6:28,235,695...28,340,577
JBrowse link
G Dtl denticleless E3 ubiquitin protein ligase homolog increases expression ISO Methylcholanthrene results in increased expression of DTL mRNA CTD PMID:20713471 NCBI chr13:110,219,276...110,257,345
Ensembl chr13:110,220,283...110,257,367
JBrowse link
G Dtna dystrobrevin, alpha multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to DTNA promoter] CTD PMID:20348232 NCBI chr18:14,544,725...14,671,514
Ensembl chr18:14,471,213...14,657,332
JBrowse link
G Dusp14 dual specificity phosphatase 14 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to DUSP14 promoter] CTD PMID:20348232 NCBI chr10:71,363,688...71,383,602
Ensembl chr10:71,363,688...71,383,602
JBrowse link
G Dusp4 dual specificity phosphatase 4 increases expression ISO Methylcholanthrene results in increased expression of DUSP4 mRNA CTD PMID:20713471 NCBI chr16:61,080,767...61,090,973
Ensembl chr16:61,078,175...61,091,169
JBrowse link
G Dusp6 dual specificity phosphatase 6 increases expression ISO Methylcholanthrene results in increased expression of DUSP6 mRNA CTD PMID:20713471 NCBI chr 7:41,475,163...41,479,393
Ensembl chr 7:41,475,163...41,479,392
JBrowse link
G Dut deoxyuridine triphosphatase increases expression ISO Methylcholanthrene results in increased expression of DUT mRNA CTD PMID:20713471 NCBI chr 3:117,514,399...117,525,450
Ensembl chr 3:117,514,444...117,525,446
JBrowse link
G Dyrk2 dual specificity tyrosine phosphorylation regulated kinase 2 decreases expression ISO Methylcholanthrene results in decreased expression of DYRK2 mRNA CTD PMID:20713471 NCBI chr 7:61,785,423...61,816,775
Ensembl chr 7:61,786,309...61,798,729
JBrowse link
G E2f7 E2F transcription factor 7 increases expression ISO Methylcholanthrene results in increased expression of E2F7 mRNA CTD PMID:20713471 NCBI chr 7:53,275,659...53,318,261
Ensembl chr 7:53,275,676...53,316,481
JBrowse link
G E2f8 E2F transcription factor 8 increases expression ISO Methylcholanthrene results in increased expression of E2F8 mRNA CTD PMID:20713471 NCBI chr 1:104,185,436...104,203,683
Ensembl chr 1:104,187,100...104,202,591
JBrowse link
G Ecm1 extracellular matrix protein 1 increases expression ISO Methylcholanthrene results in increased expression of ECM1 mRNA CTD PMID:20713471 NCBI chr 2:197,855,468...197,860,973
Ensembl chr 2:197,855,460...197,860,699
JBrowse link
G Ect2 epithelial cell transforming 2 increases expression ISO Methylcholanthrene results in increased expression of ECT2 mRNA CTD PMID:20713471 NCBI chr 2:112,769,385...112,831,476
Ensembl chr 2:112,769,385...112,831,476
JBrowse link
G Efna5 ephrin A5 decreases expression ISO Methylcholanthrene results in decreased expression of EFNA5 mRNA CTD PMID:20713471 NCBI chr 9:110,054,002...110,329,878
Ensembl chr 9:110,057,155...110,225,486
JBrowse link
G Efnb1 ephrin B1 increases expression ISO Methylcholanthrene results in increased expression of EFNB1 mRNA CTD PMID:20713471 NCBI chr  X:68,891,227...68,904,034
Ensembl chr  X:68,891,227...68,904,038
JBrowse link
G Egfr epidermal growth factor receptor decreases expression EXP Methylcholanthrene results in decreased expression of EGFR mRNA CTD PMID:29094188 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Egr2 early growth response 2 increases expression ISO Methylcholanthrene results in increased expression of EGR2 mRNA CTD PMID:29554273 NCBI chr20:22,452,170...22,461,018
Ensembl chr20:22,454,463...22,459,025
JBrowse link
G Egr3 early growth response 3 increases expression ISO Methylcholanthrene results in increased expression of EGR3 mRNA CTD PMID:20713471 NCBI chr15:51,756,683...51,762,080
Ensembl chr15:51,756,736...51,760,722
JBrowse link
G Ehd3 EH-domain containing 3 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to EHD3 promoter] CTD PMID:20348232 NCBI chr 6:25,076,012...25,102,457
Ensembl chr 6:25,074,955...25,100,977
JBrowse link
G Eif1a eukaryotic translation initiation factor 1A increases expression ISO Methylcholanthrene results in increased expression of EIF1AY mRNA CTD PMID:20713471 NCBI chr18:40,586,315...40,598,661
Ensembl chr18:40,586,315...40,597,671
JBrowse link
G Eif2b2 eukaryotic translation initiation factor 2B subunit beta increases expression ISO Methylcholanthrene results in increased expression of EIF2B2 mRNA CTD PMID:20713471 NCBI chr 6:109,044,830...109,051,254
Ensembl chr 6:109,043,880...109,051,253
JBrowse link
G Eif4e1b eukaryotic translation initiation factor 4E family member 1B multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of EIF4E1B mRNA CTD PMID:23519560 NCBI chr17:10,369,153...10,391,667 JBrowse link
G Eif4ebp2 eukaryotic translation initiation factor 4E binding protein 2 increases expression ISO Methylcholanthrene results in increased expression of EIF4EBP2 mRNA CTD PMID:25926378 NCBI chr20:31,055,292...31,072,469
Ensembl chr20:31,055,789...31,072,469
JBrowse link
G Elmo1 engulfment and cell motility 1 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ELMO1 mRNA CTD PMID:23519560 NCBI chr17:46,352,102...46,888,788
Ensembl chr17:46,353,330...46,794,845
JBrowse link
G Elovl3 ELOVL fatty acid elongase 3 increases expression ISO Methylcholanthrene results in increased expression of ELOVL3 mRNA CTD PMID:25926378 NCBI chr 1:265,883,353...265,887,181
Ensembl chr 1:265,883,355...265,887,226
JBrowse link
G Eme1 essential meiotic structure-specific endonuclease 1 increases expression ISO Methylcholanthrene results in increased expression of EME1 mRNA CTD PMID:20713471 NCBI chr10:82,366,820...82,375,510
Ensembl chr10:82,367,084...82,374,171
JBrowse link
G Emp1 epithelial membrane protein 1 increases expression ISO Methylcholanthrene results in increased expression of EMP1 mRNA CTD PMID:20713471 NCBI chr 4:169,161,076...169,181,967
Ensembl chr 4:169,147,243...169,181,966
JBrowse link
G Enpep glutamyl aminopeptidase decreases expression ISO Methylcholanthrene results in decreased expression of ENPEP mRNA CTD PMID:20713471 NCBI chr 2:233,667,253...233,743,866
Ensembl chr 2:233,667,254...233,743,866
JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 decreases expression ISO Methylcholanthrene results in decreased expression of ENPP2 mRNA CTD PMID:20713471 NCBI chr 7:94,479,931...94,563,086
Ensembl chr 7:94,480,396...94,563,001
JBrowse link
G Epas1 endothelial PAS domain protein 1 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of EPAS1 mRNA CTD PMID:23519560 NCBI chr 6:10,306,508...10,385,239
Ensembl chr 6:10,306,405...10,387,265
JBrowse link
G Ephb6 Eph receptor B6 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of EPHB6 mRNA CTD PMID:23519560 NCBI chr 4:70,903,253...70,918,514
Ensembl chr 4:70,903,253...70,918,514
JBrowse link
G Ephx1 epoxide hydrolase 1 increases activity
increases expression
ISO
EXP
Methylcholanthrene results in increased activity of EPHX1 protein
Methylcholanthrene results in increased expression of EPHX1 mRNA
CTD PMID:3621371, PMID:23273579 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link
G Ephx2 epoxide hydrolase 2 increases activity
decreases activity
increases expression
EXP
ISO
Methylcholanthrene results in increased activity of EPHX2 protein
Methylcholanthrene results in decreased activity of EPHX2 protein
Methylcholanthrene results in increased expression of EPHX2 mRNA; Methylcholanthrene results in increased expression of EPHX2 protein
CTD PMID:3621371, PMID:19889059 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279
JBrowse link
G Eps15 epidermal growth factor receptor pathway substrate 15 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to EPS15 promoter] CTD PMID:20348232 NCBI chr 5:128,923,809...129,022,268
Ensembl chr 5:128,923,934...129,022,054
JBrowse link
G Eps8 epidermal growth factor receptor pathway substrate 8 increases expression ISO Methylcholanthrene results in increased expression of EPS8 mRNA CTD PMID:20713471 NCBI chr 4:171,475,155...171,645,620
Ensembl chr 4:171,475,567...171,591,882
JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to ERCC6 promoter] CTD PMID:20348232 NCBI chr16:8,734,028...8,804,610
Ensembl chr16:8,734,035...8,804,610
JBrowse link
G Ercc6l ERCC excision repair 6 like, spindle assembly checkpoint helicase increases expression ISO Methylcholanthrene results in increased expression of ERCC6L mRNA CTD PMID:20713471 NCBI chr  X:72,018,373...72,034,140
Ensembl chr  X:72,018,373...72,034,099
JBrowse link
G Ereg epiregulin increases expression ISO Methylcholanthrene results in increased expression of EREG mRNA CTD PMID:20713471 NCBI chr14:18,577,620...18,591,395
Ensembl chr14:18,576,355...18,591,394
JBrowse link
G Esco2 establishment of sister chromatid cohesion N-acetyltransferase 2 increases expression ISO Methylcholanthrene results in increased expression of ESCO2 mRNA CTD PMID:20713471 NCBI chr15:42,500,929...42,519,019
Ensembl chr15:42,500,929...42,518,855
JBrowse link
G Espl1 extra spindle pole bodies like 1, separase increases expression ISO Methylcholanthrene results in increased expression of ESPL1 mRNA CTD PMID:20713471 NCBI chr 7:143,896,890...143,923,868
Ensembl chr 7:143,897,014...143,923,868
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
decreases expression
increases expression
increases activity
affects binding
ISO
EXP
Fulvestrant inhibits the reaction [Methylcholanthrene results in increased expression of ESR1 mRNA]; Methylcholanthrene binds to and results in increased activity of ESR1 protein; Methylcholanthrene promotes the reaction [AHR protein binds to ESR1 promoter]; Methylcholanthrene promotes the reaction [ARNT protein binds to ESR1 promoter]; Methylcholanthrene promotes the reaction [ESR1 protein binds to CYP1A1 promoter]
alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased expression of ESR1 mRNA]
Methylcholanthrene results in increased activity of ESR1 protein
Methylcholanthrene binds to ESR1 protein
CTD PMID:16257430, PMID:16489053, PMID:16972788, PMID:20348232, PMID:23273579, PMID:29094188 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Etv1 ETS variant transcription factor 1 increases expression ISO Methylcholanthrene results in increased expression of ETV1 mRNA CTD PMID:20713471 NCBI chr 6:58,467,215...58,558,640
Ensembl chr 6:58,467,254...58,558,631
JBrowse link
G Etv5 ETS variant transcription factor 5 increases expression ISO Methylcholanthrene results in increased expression of ETV5 mRNA CTD PMID:20713471 NCBI chr11:82,194,657...82,252,145
Ensembl chr11:82,194,657...82,252,139
JBrowse link
G Exo1 exonuclease 1 increases expression ISO Methylcholanthrene results in increased expression of EXO1 mRNA CTD PMID:20713471 NCBI chr13:93,936,989...93,962,749
Ensembl chr13:93,939,022...93,960,342
JBrowse link
G Exosc9 exosome component 9 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to EXOSC9 promoter] CTD PMID:20348232 NCBI chr 2:123,264,679...123,275,623
Ensembl chr 2:123,264,694...123,294,880
JBrowse link
G F11r F11 receptor multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of F11R mRNA CTD PMID:23519560 NCBI chr13:89,826,272...89,850,151
Ensembl chr13:89,826,254...89,850,612
JBrowse link
G Fabp4 fatty acid binding protein 4 decreases expression
multiple interactions
ISO Methylcholanthrene results in decreased expression of FABP4 mRNA
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of FABP4 mRNA
CTD PMID:25926378 NCBI chr 2:93,792,666...93,797,267
Ensembl chr 2:93,792,601...93,797,305
JBrowse link
G Fas Fas cell surface death receptor multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of FAS mRNA CTD PMID:23519560 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Fcar Fc fragment of IgA receptor increases expression ISO Methylcholanthrene results in increased expression of FCAR mRNA CTD PMID:21911031 NCBI chr 1:73,230,392...73,263,462
Ensembl chr 1:73,230,390...73,264,302
JBrowse link
G Fchsd2 FCH and double SH3 domains 2 increases expression ISO Methylcholanthrene results in increased expression of FCHSD2 mRNA CTD PMID:20713471 NCBI chr 1:166,140,025...166,395,915
Ensembl chr 1:166,125,474...166,395,915
JBrowse link
G Fcrl5 Fc receptor-like 5 multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of FCRL5 mRNA CTD PMID:25926378 NCBI chr 2:186,776,466...186,797,900
Ensembl chr 2:186,776,605...186,808,078
JBrowse link
G Fdps farnesyl diphosphate synthase decreases expression ISO Methylcholanthrene results in decreased expression of FDPS mRNA CTD PMID:20713471 NCBI chr 2:188,403,595...188,413,219
Ensembl chr 2:188,392,858...188,413,219
JBrowse link
G Fdxr ferredoxin reductase increases expression ISO Methylcholanthrene results in increased expression of FDXR mRNA CTD PMID:22100608 NCBI chr10:103,817,724...103,826,413
Ensembl chr10:103,817,704...103,826,448
JBrowse link
G Fgf1 fibroblast growth factor 1 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of FGF1 mRNA CTD PMID:23519560 NCBI chr18:32,273,830...32,359,831
Ensembl chr18:32,273,770...32,359,824
JBrowse link
G Fgf10 fibroblast growth factor 10 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of FGF10 mRNA CTD PMID:23519560 NCBI chr 2:51,673,480...51,747,533
Ensembl chr 2:51,672,722...51,750,369
JBrowse link
G Fgf18 fibroblast growth factor 18 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of FGF18 mRNA CTD PMID:23519560 NCBI chr10:18,047,109...18,082,290
Ensembl chr10:18,047,109...18,063,391
JBrowse link
G Fgf7 fibroblast growth factor 7 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of FGF7 mRNA CTD PMID:23519560 NCBI chr 3:118,315,859...118,368,464
Ensembl chr 3:118,317,761...118,366,872
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 increases expression ISO Methylcholanthrene results in increased expression of FGFR1 mRNA CTD PMID:20713471, PMID:29554273 NCBI chr16:71,265,390...71,319,046
Ensembl chr16:71,266,248...71,319,449
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of FGFR2 mRNA CTD PMID:23519560 NCBI chr 1:200,590,951...200,696,946
Ensembl chr 1:200,590,953...200,696,928
JBrowse link
G Fhit fragile histidine triad diadenosine triphosphatase multiple interactions
decreases expression
EXP
ISO
[Diethylnitrosamine co-treated with Methylcholanthrene] results in decreased expression of FHIT protein; [Diethylnitrosamine co-treated with Methylcholanthrene] results in increased methylation of FHIT promoter
Methylcholanthrene results in decreased expression of FHIT mRNA
CTD PMID:20970405, PMID:22100608 NCBI chr15:15,697,292...16,862,873 JBrowse link
G Fignl1 fidgetin-like 1 increases expression ISO Methylcholanthrene results in increased expression of FIGNL1 mRNA CTD PMID:20713471 NCBI chr14:91,895,902...91,904,474
Ensembl chr14:91,895,909...91,904,433
JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 increases expression ISO Methylcholanthrene results in increased expression of FMO2 mRNA CTD PMID:20570689 NCBI chr13:80,752,526...80,775,264
Ensembl chr13:80,755,058...80,775,264
JBrowse link
G Fmo3 flavin containing dimethylaniline monoxygenase 3 multiple interactions
decreases expression
increases expression
ISO
EXP
AHR protein affects the reaction [Methylcholanthrene results in increased expression of FMO3 mRNA]; Methylcholanthrene promotes the reaction [TRP53 protein binds to FMO3 5' UTR]
Methylcholanthrene results in decreased expression of FMO3 mRNA
CTD PMID:20570689, PMID:23273579, PMID:23846873, PMID:25926378 NCBI chr13:80,837,418...80,856,214
Ensembl chr13:80,837,420...80,862,963
JBrowse link
G Fmod fibromodulin decreases expression ISO Methylcholanthrene results in decreased expression of FMOD mRNA CTD PMID:20713471 NCBI chr13:50,874,886...50,885,503
Ensembl chr13:50,873,605...50,885,563
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression ISO Methylcholanthrene results in increased expression of FOSL1 mRNA CTD PMID:20713471 NCBI chr 1:220,826,560...220,835,066
Ensembl chr 1:220,826,560...220,835,066
JBrowse link
G Foxm1 forkhead box M1 affects response to substance ISO FOXM1 protein affects the susceptibility to Methylcholanthrene CTD PMID:18345025, PMID:19672312 NCBI chr 4:161,685,236...161,697,633
Ensembl chr 4:161,685,258...161,696,305
JBrowse link
G Foxn1 forkhead box N1 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to FOXN1 promoter] CTD PMID:20348232 NCBI chr10:65,621,142...65,634,666
Ensembl chr10:65,621,257...65,634,666
JBrowse link
G Foxn3 forkhead box N3 multiple interactions
increases expression
EXP alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of FOXN3 mRNA] CTD PMID:29094188 NCBI chr 6:123,183,720...123,577,719
Ensembl chr 6:123,187,726...123,577,695
JBrowse link
G Foxn4 forkhead box N4 multiple interactions
increases expression
ISO Methylcholanthrene promotes the reaction [AHR protein binds to FOXN4 promoter]; Methylcholanthrene promotes the reaction [ARNT protein binds to FOXN4 promoter]; Methylcholanthrene promotes the reaction [Methylcholanthrene results in increased expression of FOXN4 mRNA] CTD PMID:20348232 NCBI chr12:48,101,012...48,121,281
Ensembl chr12:48,101,673...48,121,270
JBrowse link
G Foxo3 forkhead box O3 multiple interactions EXP [Methylcholanthrene co-treated with alpha-naphthoflavone] results in increased expression of FOXO3 mRNA CTD PMID:29094188 NCBI chr20:46,428,078...46,519,156
Ensembl chr20:46,428,124...46,519,144
JBrowse link
G Frem2 FRAS1 related extracellular matrix 2 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to FREM2 promoter] CTD PMID:20348232 NCBI chr 2:142,747,501...142,885,604
Ensembl chr 2:142,747,501...142,885,604
JBrowse link
G Fryl FRY like transcription coactivator increases expression ISO Methylcholanthrene results in increased expression of FRYL mRNA CTD PMID:20713471 NCBI chr14:37,551,109...37,757,511
Ensembl chr14:37,551,940...37,756,149
JBrowse link
G Fst follistatin decreases expression ISO Methylcholanthrene results in decreased expression of FST mRNA CTD PMID:20713471 NCBI chr 2:46,537,589...46,544,813
Ensembl chr 2:46,538,700...46,544,457
JBrowse link
G Fstl1 follistatin-like 1 decreases expression ISO Methylcholanthrene results in decreased expression of FSTL1 mRNA CTD PMID:20713471 NCBI chr11:65,791,196...65,845,721
Ensembl chr11:65,782,567...65,845,418
JBrowse link
G Fut8 fucosyltransferase 8 increases expression ISO Methylcholanthrene results in increased expression of FUT8 mRNA CTD PMID:20713471 NCBI chr 6:100,305,957...100,537,208
Ensembl chr 6:100,337,226...100,537,224
JBrowse link
G Fxyd5 FXYD domain-containing ion transport regulator 5 increases expression ISO Methylcholanthrene results in increased expression of FXYD5 mRNA CTD PMID:20713471 NCBI chr 1:89,464,853...89,474,450
Ensembl chr 1:89,464,860...89,474,252
JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of FYN mRNA CTD PMID:23519560 NCBI chr20:44,436,354...44,630,316
Ensembl chr20:44,436,403...44,630,317
JBrowse link
G Gab2 GRB2-associated binding protein 2 decreases expression ISO Methylcholanthrene results in decreased expression of GAB2 mRNA CTD PMID:20713471 NCBI chr 1:162,082,876...162,283,379
Ensembl chr 1:162,083,030...162,279,727
JBrowse link
G Gabra3 gamma-aminobutyric acid type A receptor subunit alpha 3 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GABRA3 mRNA CTD PMID:23519560 NCBI chr  X:152,414,332...152,642,607
Ensembl chr  X:152,414,615...152,642,531
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha decreases expression ISO Methylcholanthrene results in decreased expression of GADD45A mRNA CTD PMID:20713471 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Galnt15 polypeptide N-acetylgalactosaminyltransferase 15 increases expression ISO Methylcholanthrene results in increased expression of GALNT15 mRNA CTD PMID:20713471 NCBI chr16:8,127,599...8,178,101
Ensembl chr16:8,128,689...8,177,841
JBrowse link
G Galnt18 polypeptide N-acetylgalactosaminyltransferase 18 decreases expression ISO Methylcholanthrene results in decreased expression of GALNT18 mRNA CTD PMID:20713471 NCBI chr 1:176,296,186...176,607,466
Ensembl chr 1:176,296,193...176,607,466
JBrowse link
G Galnt7 polypeptide N-acetylgalactosaminyltransferase 7 increases expression ISO Methylcholanthrene results in increased expression of GALNT7 mRNA CTD PMID:20713471 NCBI chr16:35,935,059...36,062,734
Ensembl chr16:35,934,970...36,062,719
JBrowse link
G Gas2l3 growth arrest-specific 2 like 3 increases expression ISO Methylcholanthrene results in increased expression of GAS2L3 mRNA CTD PMID:20713471 NCBI chr 7:29,963,129...29,996,021
Ensembl chr 7:29,959,597...29,986,163
JBrowse link
G Gata6 GATA binding protein 6 multiple interactions
increases activity
ISO Methylcholanthrene promotes the reaction [GATA6 protein binds to KRAS exon]
Methylcholanthrene results in increased activity of GATA6 protein
CTD PMID:16271038 NCBI chr18:2,415,821...2,447,087
Ensembl chr18:2,416,552...2,446,338
JBrowse link
G Gcat glycine C-acetyltransferase increases expression ISO Methylcholanthrene results in increased expression of GCAT mRNA CTD PMID:20713471 NCBI chr 7:120,263,068...120,269,365
Ensembl chr 7:120,263,054...120,269,451
JBrowse link
G Gch1 GTP cyclohydrolase 1 increases expression ISO Methylcholanthrene results in increased expression of GCH1 mRNA CTD PMID:20713471 NCBI chr15:23,935,011...23,968,971
Ensembl chr15:23,934,585...23,969,011
JBrowse link
G Gchfr GTP cyclohydrolase I feedback regulator increases expression ISO Methylcholanthrene results in increased expression of GCHFR mRNA CTD PMID:20713471 NCBI chr 3:110,975,923...110,979,957
Ensembl chr 3:110,975,923...110,979,957
JBrowse link
G Gdf9 growth differentiation factor 9 multiple interactions EXP [Methylcholanthrene co-treated with alpha-naphthoflavone] results in increased expression of GDF9 mRNA CTD PMID:29094188 NCBI chr10:38,782,519...38,793,238
Ensembl chr10:38,788,992...38,792,940
JBrowse link
G Gdpd4 glycerophosphodiester phosphodiesterase domain containing 4 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to GDPD4 promoter] CTD PMID:20348232 NCBI chr 1:162,890,475...162,999,851
Ensembl chr 1:162,890,475...162,969,727
JBrowse link
G Gh1 growth hormone 1 decreases activity EXP Methylcholanthrene results in decreased activity of GH1 protein CTD PMID:22978700 NCBI chr10:94,486,204...94,488,181
Ensembl chr10:94,486,205...94,488,180
JBrowse link
G Ghr growth hormone receptor decreases expression
increases expression
ISO Methylcholanthrene results in decreased expression of GHR mRNA
Methylcholanthrene results in increased expression of GHR protein
CTD PMID:22978700, PMID:23169610 NCBI chr 2:53,149,225...53,413,954
Ensembl chr 2:53,150,370...53,413,638
JBrowse link
G Gins3 GINS complex subunit 3 increases expression ISO Methylcholanthrene results in increased expression of GINS3 mRNA CTD PMID:20713471 NCBI chr19:9,835,113...9,843,649
Ensembl chr19:9,835,057...9,843,673
JBrowse link
G Gins4 GINS complex subunit 4 increases expression ISO Methylcholanthrene results in increased expression of GINS4 mRNA CTD PMID:20713471 NCBI chr16:73,584,412...73,596,808
Ensembl chr16:73,584,521...73,596,793
JBrowse link
G Gja1 gap junction protein, alpha 1 increases expression ISO Methylcholanthrene results in increased expression of GJA1 mRNA CTD PMID:20713471 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Gmnn geminin, DNA replication inhibitor increases expression ISO Methylcholanthrene results in increased expression of GMNN mRNA CTD PMID:20713471 NCBI chr17:42,302,523...42,310,783
Ensembl chr17:42,302,540...42,310,783
JBrowse link
G Gnb4 G protein subunit beta 4 increases expression ISO Methylcholanthrene results in increased expression of GNB4 mRNA CTD PMID:20713471 NCBI chr 2:118,978,965...119,007,877
Ensembl chr 2:118,978,973...119,007,835
JBrowse link
G Gnmt glycine N-methyltransferase decreases expression
multiple interactions
ISO
EXP
Methylcholanthrene results in decreased expression of GNMT mRNA
[Methylcholanthrene co-treated with GNMT protein] results in increased expression of CYP1A1 mRNA
CTD PMID:9261130, PMID:22100608 NCBI chr 9:16,565,274...16,568,626
Ensembl chr 9:16,565,225...16,568,627
JBrowse link
G Gpc1 glypican 1 increases expression ISO Methylcholanthrene results in increased expression of GPC1 mRNA CTD PMID:20713471 NCBI chr 9:99,998,275...100,026,818
Ensembl chr 9:99,998,275...100,026,818
JBrowse link
G Gpcpd1 glycerophosphocholine phosphodiesterase 1 decreases expression ISO Methylcholanthrene results in decreased expression of GPCPD1 mRNA CTD PMID:20713471 NCBI chr 3:125,169,131...125,213,598
Ensembl chr 3:125,169,135...125,213,607
JBrowse link
G Gphb5 glycoprotein hormone subunit beta 5 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to GPHB5 promoter] CTD PMID:20348232 NCBI chr 6:98,380,500...98,383,049
Ensembl chr 6:98,380,500...98,383,049
JBrowse link
G Gpnmb glycoprotein nmb increases expression ISO Methylcholanthrene results in increased expression of GPNMB mRNA CTD PMID:20713471 NCBI chr 4:78,694,447...78,715,685
Ensembl chr 4:78,694,447...78,715,683
JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression EXP
ISO
Methylcholanthrene results in increased expression of GPX1 mRNA CTD PMID:23273579, PMID:23712962 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Greb1 growth regulating estrogen receptor binding 1 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to GREB1 promoter] CTD PMID:20348232 NCBI chr 6:41,932,941...42,002,770
Ensembl chr 6:41,932,244...42,002,819
JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GRIA3 mRNA CTD PMID:23519560 NCBI chr  X:127,561,843...127,829,763
Ensembl chr  X:127,562,660...127,829,753
JBrowse link
G Grik4 glutamate ionotropic receptor kainate type subunit 4 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to GRIK4 promoter] CTD PMID:20348232 NCBI chr 8:46,804,134...47,237,546
Ensembl chr 8:46,806,147...47,094,352
JBrowse link
G Grik5 glutamate ionotropic receptor kainate type subunit 5 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GRIK5 mRNA CTD PMID:23519560 NCBI chr 1:81,885,516...81,946,731
Ensembl chr 1:81,885,521...81,946,714
JBrowse link
G Gsdmc gasdermin C multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to GSDMC promoter] CTD PMID:20348232 NCBI chr 7:104,474,418...104,492,373
Ensembl chr 7:104,474,418...104,486,710
JBrowse link
G Gsdmd gasdermin D increases expression ISO Methylcholanthrene results in increased expression of GSDMD mRNA CTD PMID:20713471 NCBI chr 7:116,889,147...116,894,134
Ensembl chr 7:116,889,572...116,894,134
JBrowse link
G Gsdme gasdermin E increases expression ISO Methylcholanthrene results in increased expression of GSDME mRNA CTD PMID:20713471 NCBI chr 4:79,934,075...79,999,678
Ensembl chr 4:79,934,887...79,989,572
JBrowse link
G Gsr glutathione-disulfide reductase increases activity
increases expression
ISO Methylcholanthrene results in increased activity of GSR protein
Methylcholanthrene results in increased expression of GSR mRNA
CTD PMID:23712962 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gss glutathione synthetase increases activity
increases expression
ISO Methylcholanthrene results in increased activity of GSS protein
Methylcholanthrene results in increased expression of GSS mRNA
CTD PMID:23712962 NCBI chr 3:151,076,254...151,106,557
Ensembl chr 3:151,076,254...151,106,557
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression
decreases expression
multiple interactions
EXP
ISO
Methylcholanthrene results in increased expression of GSTA2 mRNA
Methylcholanthrene results in decreased expression of GSTA1 mRNA
Methylcholanthrene results in decreased expression of GSTA2 mRNA
[Methylcholanthrene co-treated with Copper] results in increased activity of GSTA2 protein; Copper inhibits the reaction [Methylcholanthrene results in increased expression of GSTA2 mRNA]; Lead inhibits the reaction [Methylcholanthrene results in increased expression of GSTA2 mRNA]; Mercury promotes the reaction [Methylcholanthrene results in increased expression of GSTA2 mRNA]
CTD PMID:10476907, PMID:11328961, PMID:15297030, PMID:23273579, PMID:23712962 NCBI chr 8:85,640,081...85,645,621 JBrowse link
G Gsta6 glutathione S-transferase alpha 6 multiple interactions
decreases expression
increases expression
ISO [Methylcholanthrene co-treated with Copper] results in increased activity of GSTA2 protein; Copper inhibits the reaction [Methylcholanthrene results in increased expression of GSTA2 mRNA]; Lead inhibits the reaction [Methylcholanthrene results in increased expression of GSTA2 mRNA]; Mercury promotes the reaction [Methylcholanthrene results in increased expression of GSTA2 mRNA]
Methylcholanthrene results in decreased expression of GSTA1 mRNA
CTD PMID:15297030, PMID:23712962 NCBI chr 9:27,475,273...27,533,939
Ensembl chr 9:27,475,273...27,511,176
JBrowse link
G Gstk1 glutathione S-transferase kappa 1 increases expression EXP Methylcholanthrene results in increased expression of GSTK1 mRNA CTD PMID:23273579 NCBI chr 4:71,621,777...71,626,096
Ensembl chr 4:71,621,729...71,626,107
JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression EXP Methylcholanthrene results in increased expression of GSTM1 mRNA CTD PMID:11328961, PMID:23273579 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases expression EXP Methylcholanthrene results in increased expression of GSTP1 mRNA CTD PMID:19118567, PMID:23273579 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Gtse1 G-2 and S-phase expressed 1 increases expression ISO Methylcholanthrene results in increased expression of GTSE1 mRNA CTD PMID:20713471 NCBI chr 7:126,736,416...126,753,221
Ensembl chr 7:126,736,732...126,753,220
JBrowse link
G Gulp1 GULP PTB domain containing engulfment adaptor 1 increases expression ISO Methylcholanthrene results in increased expression of GULP1 mRNA CTD PMID:23397585 NCBI chr 9:51,263,484...51,538,066
Ensembl chr 9:51,263,622...51,538,072
JBrowse link
G H2bc1 H2B clustered histone 1 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to H2BC1 promoter] CTD PMID:20348232 NCBI chr17:43,423,111...43,423,580
Ensembl chr17:43,423,111...43,423,580
JBrowse link
G H3f3b H3.3 histone B decreases expression ISO Methylcholanthrene results in decreased expression of H3F3B mRNA CTD PMID:20713471 NCBI chr10:104,573,666...104,575,890
Ensembl chr10:104,573,664...104,575,890
JBrowse link
G Hacd4 3-hydroxyacyl-CoA dehydratase 4 increases expression ISO Methylcholanthrene results in increased expression of HACD4 mRNA CTD PMID:20713471 NCBI chr 5:106,728,401...106,758,068
Ensembl chr 5:106,732,513...106,758,032
JBrowse link
G Haspin histone H3 associated protein kinase increases expression ISO Methylcholanthrene results in increased expression of HASPIN mRNA CTD PMID:20713471 NCBI chr10:59,695,403...59,698,398
Ensembl chr10:59,695,913...59,698,168
JBrowse link
G Hba-a1 hemoglobin alpha, adult chain 1 increases expression ISO Methylcholanthrene results in increased expression of HBA-A1 mRNA CTD PMID:20713471 NCBI chr10:15,602,794...15,603,649
Ensembl chr10:15,602,794...15,603,649
JBrowse link
G Hck HCK proto-oncogene, Src family tyrosine kinase multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of HCK mRNA CTD PMID:23519560 NCBI chr 3:148,579,917...148,623,026
Ensembl chr 3:148,579,920...148,623,033
JBrowse link
G Hcrtr2 hypocretin receptor 2 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to HCRTR2 promoter] CTD PMID:20348232 NCBI chr 8:83,307,684...83,421,612
Ensembl chr 8:83,307,684...83,421,612
JBrowse link
G Hdac11 histone deacetylase 11 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to HDAC11 promoter] CTD PMID:20348232 NCBI chr 4:122,781,095...122,798,355
Ensembl chr 4:122,781,095...122,798,353
JBrowse link
G Hdac5 histone deacetylase 5 increases expression ISO Methylcholanthrene results in increased expression of HDAC5 mRNA CTD PMID:29554273 NCBI chr10:90,140,183...90,169,853
Ensembl chr10:90,140,183...90,151,042
JBrowse link
G Heph hephaestin increases expression ISO Methylcholanthrene results in increased expression of HEPH mRNA CTD PMID:20713471 NCBI chr  X:65,377,313...65,658,479
Ensembl chr  X:65,563,122...65,658,516
JBrowse link
G Hes1 hes family bHLH transcription factor 1 multiple interactions
increases expression
EXP alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to HES1 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of HES1 mRNA]; Methylcholanthrene promotes the reaction [AHR protein binds to HES1 promoter] CTD PMID:29094188 NCBI chr11:74,312,837...74,315,249
Ensembl chr11:74,312,806...74,315,248
JBrowse link
G Hgf hepatocyte growth factor multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of HGF mRNA CTD PMID:23519560 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
JBrowse link
G Hhip Hedgehog-interacting protein multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of HHIP mRNA CTD PMID:23519560 NCBI chr19:31,525,134...31,614,487
Ensembl chr19:31,524,671...31,614,246
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression EXP Methylcholanthrene results in increased expression of HIF1A mRNA CTD PMID:23273579 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 decreases expression ISO Methylcholanthrene results in decreased expression of HIPK2 mRNA CTD PMID:20713471 NCBI chr 4:66,438,390...66,625,183
Ensembl chr 4:66,445,266...66,624,912
JBrowse link
G Hmga1 high mobility group AT-hook 1 increases expression ISO Methylcholanthrene results in increased expression of HMGA1 mRNA CTD PMID:20713471 NCBI chr20:7,132,501...7,140,155
Ensembl chr20:7,136,007...7,138,980
JBrowse link
G Hmga2 high mobility group AT-hook 2 increases expression ISO Methylcholanthrene results in increased expression of HMGA2 mRNA CTD PMID:20713471 NCBI chr 7:65,159,944...65,275,408
Ensembl chr 7:65,159,944...65,275,408
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 decreases expression ISO Methylcholanthrene results in decreased expression of HMGCS1 mRNA CTD PMID:20713471 NCBI chr 2:52,427,351...52,445,082
Ensembl chr 2:52,431,601...52,445,055
JBrowse link
G Hmmr hyaluronan-mediated motility receptor increases expression ISO Methylcholanthrene results in increased expression of HMMR mRNA CTD PMID:20713471 NCBI chr10:25,861,490...25,890,639
Ensembl chr10:25,861,490...25,890,639
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO
EXP
[Methylcholanthrene co-treated with Copper] results in increased expression of HMOX1 mRNA; [Methylcholanthrene co-treated with Lead] results in increased expression of HMOX1 mRNA; [Methylcholanthrene co-treated with Mercury] results in increased expression of HMOX1 mRNA
Methylcholanthrene results in increased expression of HMOX1 mRNA
CTD PMID:15297030, PMID:19889059, PMID:22100608 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 multiple interactions ISO [Butylated Hydroxytoluene co-treated with Methylcholanthrene] affects the localization of HNRNPA1 protein; [Butylated Hydroxytoluene co-treated with Methylcholanthrene] results in increased expression of HNRNPA1 protein CTD PMID:15390079 NCBI chr 7:144,865,302...144,871,592
Ensembl chr 7:144,865,608...144,871,585
JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 multiple interactions ISO [Methylcholanthrene co-treated with Butylated Hydroxytoluene] affects the expression of HNRNPA2B1 protein CTD PMID:17477362 NCBI chr 4:81,237,496...81,241,281
Ensembl chr 4:81,237,496...81,241,282
JBrowse link
G Hoxc10 homeo box C10 increases expression ISO Methylcholanthrene results in increased expression of HOXC10 mRNA CTD PMID:20348232 NCBI chr 7:144,577,578...144,582,802
Ensembl chr 7:144,577,465...144,582,622
JBrowse link
G Hoxc11 homeobox C11 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to HOXC11 promoter] CTD PMID:20348232 NCBI chr 7:144,565,392...144,568,580
Ensembl chr 7:144,565,392...144,567,580
JBrowse link
G Hpcal4 hippocalcin-like 4 increases expression ISO Methylcholanthrene results in increased expression of HPCAL4 mRNA CTD PMID:25926378 NCBI chr 5:140,870,127...140,882,242
Ensembl chr 5:140,870,140...140,882,244
JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase increases expression ISO Methylcholanthrene results in increased expression of HPGD mRNA CTD PMID:25926378 NCBI chr16:37,457,134...37,495,758
Ensembl chr16:37,457,135...37,495,758
JBrowse link
G Hsbp1 heat shock factor binding protein 1 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to HSBP1 promoter] CTD PMID:20348232 NCBI chr19:51,985,196...51,989,528
Ensembl chr19:51,985,170...51,989,544
JBrowse link
G Hscb HscB mitochondrial iron-sulfur cluster co-chaperone multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of HSCB mRNA CTD PMID:25926378 NCBI chr12:51,878,267...51,888,645
Ensembl chr12:51,878,153...51,888,669
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 increases expression EXP Methylcholanthrene results in increased expression of HSP90AA1 mRNA CTD PMID:23273579 NCBI chr 6:135,107,262...135,112,793
Ensembl chr 6:135,107,271...135,112,775
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of HSPA1A mRNA CTD PMID:23519560 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 multiple interactions
increases expression
EXP alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of HSPA8 mRNA] CTD PMID:29094188 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
JBrowse link
G Icam1 intercellular adhesion molecule 1 increases acetylation
multiple interactions
increases expression
EXP Methylcholanthrene results in increased acetylation of ICAM1 promoter
alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to ICAM1 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased acetylation of ICAM1 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of ICAM1 mRNA]; Methylcholanthrene promotes the reaction [AHR protein binds to ICAM1 promoter]
CTD PMID:29094188 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Id2 inhibitor of DNA binding 2 increases expression ISO Methylcholanthrene results in increased expression of ID2 mRNA CTD PMID:20713471, PMID:23397585 NCBI chr 6:44,360,077...44,361,908
Ensembl chr 6:44,348,501...44,363,915
JBrowse link
G Id3 inhibitor of DNA binding 3, HLH protein increases expression ISO Methylcholanthrene results in increased expression of ID3 mRNA CTD PMID:23397585 NCBI chr 5:154,489,603...154,491,172
Ensembl chr 5:154,489,590...154,491,223
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to IDH2 promoter] CTD PMID:20348232 NCBI chr 1:141,874,354...141,893,674
Ensembl chr 1:141,866,283...141,893,705
JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 decreases expression ISO Methylcholanthrene results in decreased expression of IDI1 mRNA CTD PMID:20713471 NCBI chr17:57,976,266...57,984,036
Ensembl chr17:57,976,268...57,984,036
JBrowse link
G Ier3 immediate early response 3 increases expression
multiple interactions
ISO Methylcholanthrene results in increased expression of IER3 mRNA
Methylcholanthrene promotes the reaction [AHR protein binds to IER3 promoter]
CTD PMID:20348232, PMID:20713471, PMID:22579512 NCBI chr20:3,438,798...3,440,002
Ensembl chr20:3,438,798...3,440,769
JBrowse link
G Ifi27 interferon, alpha-inducible protein 27 decreases expression ISO Methylcholanthrene results in decreased expression of IFI27 mRNA CTD PMID:20713471 NCBI chr 6:127,327,959...127,334,430
Ensembl chr 6:127,327,959...127,334,428
JBrowse link
G Ifi44 interferon-induced protein 44 decreases expression ISO Methylcholanthrene results in decreased expression of IFI44 mRNA CTD PMID:20713471 NCBI chr 2:256,897,765...256,915,591
Ensembl chr 2:256,897,772...256,915,569
JBrowse link
G Ifit2 interferon-induced protein with tetratricopeptide repeats 2 increases expression ISO Methylcholanthrene results in increased expression of IFIT2 mRNA CTD PMID:29554273 NCBI chr 1:252,894,663...252,900,727
Ensembl chr 1:252,894,663...252,900,726
JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 decreases expression ISO Methylcholanthrene results in decreased expression of IFIT3 mRNA CTD PMID:20713471 NCBI chr 1:252,906,234...252,911,377
Ensembl chr 1:252,906,234...252,911,382
JBrowse link
G Ifnb1 interferon beta 1 increases expression ISO Methylcholanthrene results in increased expression of IFNB1 mRNA CTD PMID:29554273 NCBI chr 5:106,865,192...106,865,746
Ensembl chr 5:106,865,192...106,865,746
JBrowse link
G Igf2 insulin-like growth factor 2 increases acetylation
multiple interactions
increases expression
increases methylation
EXP Methylcholanthrene results in increased acetylation of IGF2 promoter
alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to IGF2 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased acetylation of IGF2 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of IGF2 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased methylation of IGF2 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to IGF2 promoter]
CTD PMID:29094188 NCBI chr 1:215,828,102...215,839,081
Ensembl chr 1:215,828,102...215,846,911
JBrowse link
G Igfbp6 insulin-like growth factor binding protein 6 increases expression ISO Methylcholanthrene results in increased expression of IGFBP6 mRNA CTD PMID:20713471 NCBI chr 7:143,749,385...143,754,018
Ensembl chr 7:143,749,221...143,754,054
JBrowse link
G Igfbpl1 insulin-like growth factor binding protein-like 1 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to IGFBPL1 promoter] CTD PMID:20348232 NCBI chr 5:61,395,407...61,410,812
Ensembl chr 5:61,395,408...61,410,812
JBrowse link
G Il12a interleukin 12A increases expression ISO Methylcholanthrene results in increased expression of IL12A mRNA CTD PMID:14993811 NCBI chr 2:165,076,945...165,083,996
Ensembl chr 2:165,076,607...165,084,318
JBrowse link
G Il12rb1 interleukin 12 receptor subunit beta 1 increases expression ISO Methylcholanthrene results in increased expression of IL12RB1 mRNA CTD PMID:20713471 NCBI chr16:20,370,722...20,383,576
Ensembl chr16:20,371,338...20,383,337
JBrowse link
G Il18 interleukin 18 increases expression ISO Methylcholanthrene results in increased expression of IL18 mRNA CTD PMID:14993811 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il18r1 interleukin 18 receptor 1 multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of IL18R1 mRNA CTD PMID:25926378 NCBI chr 9:47,184,404...47,217,403
Ensembl chr 9:47,185,443...47,219,175
JBrowse link
G Il18rap interleukin 18 receptor accessory protein increases expression ISO Methylcholanthrene results in increased expression of IL18RAP mRNA CTD PMID:20713471 NCBI chr 9:47,225,543...47,255,805
Ensembl chr 9:47,225,585...47,258,503
JBrowse link
G Il1a interleukin 1 alpha increases expression ISO Methylcholanthrene results in increased expression of IL1A mRNA CTD PMID:14993811 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions
ISO Methylcholanthrene results in increased expression of IL1B mRNA
[Methylcholanthrene results in increased activity of AHR protein] which results in increased expression of IL1B mRNA; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of IL1B mRNA]
CTD PMID:14993811 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 increases expression ISO Methylcholanthrene results in increased expression of IL1RL1 mRNA CTD PMID:20713471 NCBI chr 9:47,133,483...47,184,316
Ensembl chr 9:47,134,034...47,182,170
JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions
ISO Methylcholanthrene results in increased expression of IL6 mRNA
[Methylcholanthrene co-treated with TNF protein] results in increased expression of IL6 mRNA
CTD PMID:14993811, PMID:23396138, PMID:29554273 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Il6st interleukin 6 signal transducer multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of IL6ST mRNA CTD PMID:25926378 NCBI chr 2:44,279,199...44,319,427
Ensembl chr 2:44,289,393...44,314,944
JBrowse link
G Il7r interleukin 7 receptor multiple interactions
increases expression
ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of IL7R mRNA
Methylcholanthrene results in increased expression of IL7R mRNA
CTD PMID:25926378
G Immp2l inner mitochondrial membrane peptidase subunit 2 decreases expression ISO Methylcholanthrene results in decreased expression of IMMP2L mRNA CTD PMID:20713471 NCBI chr 6:60,958,351...61,859,457 JBrowse link
G Inhbc inhibin subunit beta C multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to INHBC promoter] CTD PMID:20348232 NCBI chr 7:70,648,005...70,661,475
Ensembl chr 7:70,646,519...70,661,891
JBrowse link
G Iqgap3 IQ motif containing GTPase activating protein 3 increases expression ISO Methylcholanthrene results in increased expression of IQGAP3 mRNA CTD PMID:20713471 NCBI chr 2:187,447,477...187,489,630
Ensembl chr 2:187,447,501...187,489,630
JBrowse link
G Irf2bpl interferon regulatory factor 2 binding protein-like multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to IRF2BPL promoter] CTD PMID:20348232 NCBI chr 6:110,901,940...110,904,288
Ensembl chr 6:110,901,940...110,904,288
JBrowse link
G Irs1 insulin receptor substrate 1 decreases expression ISO Methylcholanthrene results in decreased expression of IRS1 mRNA CTD PMID:29554273 NCBI chr 9:88,033,668...88,086,488
Ensembl chr 9:88,033,668...88,086,488
JBrowse link
G Isoc2b isochorismatase domain containing 2b multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to ISOC2 promoter] CTD PMID:20348232 NCBI chr 1:72,524,569...72,545,331
Ensembl chr 1:72,524,569...72,545,329
JBrowse link
G Itga10 integrin subunit alpha 10 increases expression ISO Methylcholanthrene results in increased expression of ITGA10 mRNA CTD PMID:20713471 NCBI chr 2:198,772,937...198,792,253
Ensembl chr 2:198,772,937...198,792,253
JBrowse link
G Itga7 integrin subunit alpha 7 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ITGA7 mRNA CTD PMID:23519560 NCBI chr 7:3,355,079...3,383,886
Ensembl chr 7:3,355,116...3,384,675
JBrowse link
G Itgb5 integrin subunit beta 5 decreases expression ISO Methylcholanthrene results in decreased expression of ITGB5 mRNA CTD PMID:23397585 NCBI chr11:70,056,500...70,172,164
Ensembl chr11:70,056,500...70,172,372
JBrowse link
G Itgb8 integrin subunit beta 8 decreases expression
multiple interactions
EXP Methylcholanthrene results in decreased expression of ITGB8 mRNA
alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased expression of ITGB8 mRNA]
CTD PMID:29094188 NCBI chr 6:147,089,280...147,172,846
Ensembl chr 6:147,094,097...147,172,813
JBrowse link
G Itgbl1 integrin subunit beta like 1 increases expression ISO Methylcholanthrene results in increased expression of ITGBL1 mRNA CTD PMID:20713471 NCBI chr15:110,114,148...110,378,970
Ensembl chr15:110,114,148...110,378,969
JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 multiple interactions
increases expression
ISO Methylcholanthrene promotes the reaction [AHR protein binds to ITPR1 promoter]
Methylcholanthrene results in increased expression of ITPR1 mRNA
CTD PMID:20348232 NCBI chr 4:140,247,297...140,580,749
Ensembl chr 4:140,247,313...140,580,748
JBrowse link
G Jag1 jagged canonical Notch ligand 1 decreases expression
increases expression
multiple interactions
increases acetylation
increases methylation
ISO
EXP
Methylcholanthrene results in decreased expression of JAG1 mRNA
Methylcholanthrene results in increased expression of JAG1 mRNA
alpha-naphthoflavone inhibits the reaction [Methylcholanthrene promotes the reaction [AHR protein binds to JAG1 promoter]]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased acetylation of JAG1 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of JAG1 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased methylation of JAG1 promoter]; Methylcholanthrene promotes the reaction [AHR protein binds to JAG1 promoter]
CTD PMID:20713471, PMID:29094188 NCBI chr 3:130,079,361...130,114,781
Ensembl chr 3:130,079,361...130,114,770
JBrowse link
G Jak2 Janus kinase 2 decreases expression ISO Methylcholanthrene results in decreased expression of JAK2 mRNA CTD PMID:22978700 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509
JBrowse link
G Jph1 junctophilin 1 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to JPH1 promoter] CTD PMID:20348232 NCBI chr 5:1,417,414...1,511,754
Ensembl chr 5:1,417,478...1,511,416
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression ISO Methylcholanthrene results in increased expression of JUN mRNA CTD PMID:20713471 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Katnal2 katanin catalytic subunit A1 like 2 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to KATNAL2 promoter] CTD PMID:20348232 NCBI chr18:73,283,756...73,360,367
Ensembl chr18:73,283,748...73,360,373
JBrowse link
G Kb15 type II keratin Kb15 multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of KRT6A mRNA; [Methylcholanthrene co-treated with Nanotubes, Carbon] results in increased expression of KRT6A mRNA CTD PMID:25926378 NCBI chr 7:143,208,034...143,217,771
Ensembl chr 7:143,208,527...143,217,535
JBrowse link
G Kcnk2 potassium two pore domain channel subfamily K member 2 increases expression ISO Methylcholanthrene results in increased expression of KCNK2 mRNA CTD PMID:20713471 NCBI chr13:107,690,111...107,886,476
Ensembl chr13:107,690,087...107,886,476
JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 increases expression ISO Methylcholanthrene results in increased expression of KCNN4 mRNA CTD PMID:20713471 NCBI chr 1:81,227,855...81,245,986
Ensembl chr 1:81,230,612...81,245,996
JBrowse link
G Kctd1 potassium channel tetramerization domain containing 1 increases expression ISO Methylcholanthrene results in increased expression of KCTD1 mRNA CTD PMID:25926378 NCBI chr18:6,374,778...6,474,990
Ensembl chr18:6,374,778...6,474,990
JBrowse link
G Kctd16 potassium channel tetramerization domain containing 16 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to KCTD16 promoter] CTD PMID:20348232 NCBI chr18:33,443,362...33,730,642 JBrowse link
G Kctd3 potassium channel tetramerization domain containing 3 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to KCTD3 promoter] CTD PMID:20348232 NCBI chr13:107,433,588...107,471,843
Ensembl chr13:107,433,588...107,471,843
JBrowse link
G Kctd5 potassium channel tetramerization domain containing 5 decreases expression ISO Methylcholanthrene results in decreased expression of KCTD5 mRNA CTD PMID:20713471 NCBI chr10:13,420,152...13,446,323
Ensembl chr10:13,420,154...13,446,135
JBrowse link
G Kdr kinase insert domain receptor multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of KDR mRNA CTD PMID:25926378 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 increases expression ISO Methylcholanthrene results in increased expression of KEAP1 mRNA CTD PMID:23712962 NCBI chr 8:22,250,518...22,259,868
Ensembl chr 8:22,250,518...22,259,779
JBrowse link
G Kif11 kinesin family member 11 increases expression
multiple interactions
ISO
EXP
Methylcholanthrene results in increased expression of KIF11 mRNA
Methylcholanthrene inhibits the reaction [8-prenylnaringenin results in increased expression of KIF11 mRNA]
CTD PMID:20713471, PMID:26372666 NCBI chr 1:256,035,866...256,088,299
Ensembl chr 1:256,035,866...256,088,299
JBrowse link
G Kif18a kinesin family member 18A increases expression
multiple interactions
ISO
EXP
Methylcholanthrene results in increased expression of KIF18A mRNA
Methylcholanthrene inhibits the reaction [8-prenylnaringenin results in increased expression of KIF18A mRNA]
CTD PMID:20713471, PMID:26372666 NCBI chr 3:100,366,168...100,426,867
Ensembl chr 3:100,366,168...100,427,030
JBrowse link
G Kif20a kinesin family member 20A increases expression ISO Methylcholanthrene results in increased expression of KIF20A mRNA CTD PMID:20713471 NCBI chr18:27,424,328...27,432,814
Ensembl chr18:27,424,328...27,432,814
JBrowse link
G Kif22 kinesin family member 22 increases expression ISO Methylcholanthrene results in increased expression of KIF22 mRNA CTD PMID:20713471 NCBI chr 1:198,461,406...198,476,430
Ensembl chr 1:198,461,169...198,476,476
JBrowse link
G Kif23 kinesin family member 23 increases expression ISO Methylcholanthrene results in increased expression of KIF23 mRNA CTD PMID:20713471 NCBI chr 8:66,866,043...66,893,241
Ensembl chr 8:66,866,082...66,893,196
JBrowse link
G Kif2c kinesin family member 2C increases expression ISO
EXP
Methylcholanthrene results in increased expression of KIF2C mRNA CTD PMID:20713471, PMID:26372666 NCBI chr 5:136,027,923...136,053,268
Ensembl chr 5:136,027,934...136,053,210
JBrowse link
G Kitlg KIT ligand increases expression ISO Methylcholanthrene results in increased expression of KITL mRNA CTD PMID:20713471 NCBI chr 7:42,269,784...42,351,054
Ensembl chr 7:42,269,784...42,351,054
JBrowse link
G Klf2 Kruppel-like factor 2 increases expression ISO Methylcholanthrene results in increased expression of KLF2 mRNA CTD PMID:20713471 NCBI chr16:19,223,087...19,225,037
Ensembl chr16:19,223,087...19,225,037
JBrowse link
G Klf5 Kruppel-like factor 5 increases expression ISO Methylcholanthrene results in increased expression of KLF5 mRNA CTD PMID:20713471 NCBI chr15:83,703,796...83,722,921
Ensembl chr15:83,703,791...83,722,921
JBrowse link
G Klf9 Kruppel-like factor 9 multiple interactions
decreases expression
ISO Methylcholanthrene promotes the reaction [AHR protein binds to KLF9 promoter]
Methylcholanthrene results in decreased expression of KLF9 mRNA
CTD PMID:20348232, PMID:23397585 NCBI chr 1:240,908,483...240,933,198
Ensembl chr 1:240,908,483...240,933,198
JBrowse link
G Kmt2e lysine methyltransferase 2E increases expression ISO Methylcholanthrene results in increased expression of KMT2E mRNA CTD PMID:25926378 NCBI chr 4:8,187,751...8,255,578
Ensembl chr 4:8,187,751...8,255,514
JBrowse link
G Kng2 kininogen 2 multiple interactions
decreases expression
ISO AHR protein promotes the reaction [Methylcholanthrene results in decreased expression of KNG1 mRNA]; AHR protein promotes the reaction [Methylcholanthrene results in decreased expression of KNG1 protein]
Methylcholanthrene results in decreased expression of KNG1 mRNA; Methylcholanthrene results in decreased expression of KNG1 protein
CTD PMID:11549291 NCBI chr11:81,509,185...81,516,759 JBrowse link
G Knstrn kinetochore-localized astrin/SPAG5 binding protein increases expression ISO Methylcholanthrene results in increased expression of KNSTRN mRNA CTD PMID:20713471 NCBI chr 3:110,618,256...110,638,024
Ensembl chr 3:110,618,298...110,638,046
JBrowse link
G Kntc1 kinetochore associated 1 increases expression ISO Methylcholanthrene results in increased expression of KNTC1 mRNA CTD PMID:20713471 NCBI chr12:38,200,463...38,274,162
Ensembl chr12:38,200,463...38,274,036
JBrowse link
G Kpna2 karyopherin subunit alpha 2 increases expression ISO Methylcholanthrene results in increased expression of KPNA2 mRNA CTD PMID:20713471 NCBI chr10:95,200,029...95,212,111
Ensembl chr10:95,200,030...95,212,111
JBrowse link
G Kras KRAS proto-oncogene, GTPase multiple interactions
increases mutagenesis
ISO Methylcholanthrene promotes the reaction [GATA6 protein binds to KRAS exon]; Methylcholanthrene promotes the reaction [NFYA protein binds to KRAS exon]
Methylcholanthrene results in increased mutagenesis of KRAS gene
CTD PMID:11195466, PMID:16271038, PMID:20101149 NCBI chr 4:179,482,562...179,515,483
Ensembl chr 4:179,486,105...179,515,558
JBrowse link
G Krt75 keratin 75 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to KRT75 promoter] CTD PMID:20348232 NCBI chr 7:143,219,012...143,228,237
Ensembl chr 7:143,219,012...143,228,060
JBrowse link
G Lama4 laminin subunit alpha 4 decreases expression ISO Methylcholanthrene results in decreased expression of LAMA4 mRNA CTD PMID:29554273 NCBI chr20:44,060,715...44,201,966
Ensembl chr20:44,060,731...44,209,614
JBrowse link
G Lama5 laminin subunit alpha 5 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of LAMA5 mRNA CTD PMID:23519560 NCBI chr 3:175,553,042...175,601,112
Ensembl chr 3:175,553,045...175,601,127
JBrowse link
G Lamc2 laminin subunit gamma 2 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of LAMC2 mRNA CTD PMID:23519560 NCBI chr13:70,566,643...70,632,126
Ensembl chr13:70,566,643...70,626,252
JBrowse link
G Lcat lecithin cholesterol acyltransferase decreases expression EXP Methylcholanthrene results in decreased expression of LCAT mRNA CTD PMID:11328961 NCBI chr19:37,913,333...37,916,799
Ensembl chr19:37,913,336...37,916,813
JBrowse link
G Lef1 lymphoid enhancer binding factor 1 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of LEF1 mRNA CTD PMID:23519560 NCBI chr 2:236,232,115...236,345,061
Ensembl chr 2:236,233,239...236,345,056
JBrowse link
G Lgals1 galectin 1 increases expression ISO Methylcholanthrene results in increased expression of LGALS1 mRNA CTD PMID:22579512 NCBI chr 7:120,153,184...120,156,290
Ensembl chr 7:120,153,184...120,156,289
JBrowse link
G Lgals2 galectin 2 increases expression ISO Methylcholanthrene results in increased expression of LGALS2 mRNA CTD PMID:20713471 NCBI chr 7:120,071,122...120,077,612
Ensembl chr 7:120,071,124...120,077,612
JBrowse link
G Lgals3 galectin 3 increases expression ISO Methylcholanthrene results in increased expression of LGALS3 mRNA CTD PMID:20713471 NCBI chr15:24,153,602...24,165,537
Ensembl chr15:24,141,651...24,165,537
JBrowse link
G Lgals8 galectin 8 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to LGALS8 promoter] CTD PMID:20348232 NCBI chr17:66,487,451...66,515,316
Ensembl chr17:66,487,457...66,511,870
JBrowse link
G Lgi1 leucine-rich, glioma inactivated 1 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to LGI1 promoter] CTD PMID:20348232 NCBI chr 1:256,955,944...256,996,835
Ensembl chr 1:256,955,652...256,999,253
JBrowse link
G Lif LIF, interleukin 6 family cytokine increases expression
multiple interactions
ISO Methylcholanthrene results in increased expression of LIF mRNA
Methylcholanthrene promotes the reaction [AHR protein binds to LIF promoter]
CTD PMID:20348232, PMID:20713471 NCBI chr14:84,482,652...84,500,574
Ensembl chr14:84,482,674...84,500,642
JBrowse link
G Lima1 LIM domain and actin binding 1 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to LIMA1 promoter] CTD PMID:20348232 NCBI chr 7:141,428,113...141,528,447
Ensembl chr 7:141,428,063...141,528,397
JBrowse link
G Lmnb1 lamin B1 increases expression ISO Methylcholanthrene results in increased expression of LMNB1 mRNA CTD PMID:20713471 NCBI chr18:51,785,111...51,822,264
Ensembl chr18:51,785,111...51,822,264
JBrowse link
G Lmtk2 lemur tyrosine kinase 2 multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in increased expression of LMTK2 mRNA CTD PMID:25926378 NCBI chr12:12,409,876...12,546,111
Ensembl chr12:12,409,876...12,546,111
JBrowse link
G LOC498368 similar to RIKEN cDNA 0610040J01 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to C4ORF19 promoter] CTD PMID:20348232 NCBI chr14:46,050,752...46,134,770
Ensembl chr14:46,050,750...46,054,022
JBrowse link
G Lox lysyl oxidase decreases expression ISO Methylcholanthrene results in decreased expression of LOX mRNA CTD PMID:20713471 NCBI chr18:47,500,320...47,577,819
Ensembl chr18:47,500,330...47,577,819
JBrowse link
G Lrp11 LDL receptor related protein 11 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to LRP11 promoter] CTD PMID:20348232 NCBI chr 1:1,702,696...1,731,210
Ensembl chr 1:1,702,696...1,731,210
JBrowse link
G Lrr1 leucine rich repeat protein 1 increases expression ISO Methylcholanthrene results in increased expression of LRR1 mRNA CTD PMID:20713471 NCBI chr 6:91,463,205...91,472,308
Ensembl chr 6:91,463,308...91,472,308
JBrowse link
G Lrrc8d leucine rich repeat containing 8 VRAC subunit D increases expression ISO Methylcholanthrene results in increased expression of LRRC8D mRNA CTD PMID:20713471 NCBI chr14:5,085,606...5,194,808
Ensembl chr14:5,086,054...5,101,177
JBrowse link
G Lsm4 LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated increases expression ISO Methylcholanthrene results in increased expression of LSM4 mRNA CTD PMID:20713471 NCBI chr16:20,506,399...20,511,818
Ensembl chr16:20,506,399...20,511,818
JBrowse link
G Lsm5 LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to LSM5 promoter] CTD PMID:20348232 NCBI chr 4:87,016,003...87,019,219
Ensembl chr 4:87,016,003...87,019,219
Ensembl chr 6:87,016,003...87,019,219
JBrowse link
G Lsm6 LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated increases expression ISO Methylcholanthrene results in increased expression of LSM6 mRNA CTD PMID:20713471 NCBI chr19:32,770,640...32,785,215
Ensembl chr19:32,770,655...32,785,215
JBrowse link
G Ltbp1 latent transforming growth factor beta binding protein 1 increases expression ISO Methylcholanthrene results in increased expression of LTBP1 mRNA CTD PMID:20713471 NCBI chr 6:21,203,502...21,600,441
Ensembl chr 6:21,203,502...21,600,451
JBrowse link
G Lum lumican decreases expression ISO Methylcholanthrene results in decreased expression of LUM mRNA CTD PMID:20713471 NCBI chr 7:38,820,058...38,826,862
Ensembl chr 7:38,819,771...38,826,862
JBrowse link
G Ly6e lymphocyte antigen 6 family member E multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to LY6E promoter] CTD PMID:20348232 NCBI chr 7:116,355,426...116,359,862
Ensembl chr 7:116,355,698...116,359,862
JBrowse link
G Mad1l1 mitotic arrest deficient 1 like 1 increases expression ISO Methylcholanthrene results in increased expression of MAD1L1 mRNA CTD PMID:20713471 NCBI chr12:16,410,083...16,721,232
Ensembl chr12:16,410,083...16,719,824
JBrowse link
G Magi1 membrane associated guanylate kinase, WW and PDZ domain containing 1 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of MAGI1 mRNA CTD PMID:23519560 NCBI chr 4:125,684,816...126,300,013
Ensembl chr 4:125,687,307...125,958,112
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 increases expression ISO Methylcholanthrene results in increased expression of MAP2K1 mRNA CTD PMID:25926378 NCBI chr 8:69,134,218...69,722,573
Ensembl chr 8:69,134,223...69,164,758
JBrowse link
G Map2k3 mitogen activated protein kinase kinase 3 increases expression ISO Methylcholanthrene results in increased expression of MAP2K3 mRNA CTD PMID:20713471 NCBI chr10:45,089,455...45,110,802
Ensembl chr10:47,182,433...47,203,753
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases expression ISO Methylcholanthrene results in increased expression of MAPK1 mRNA CTD PMID:23712962 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO Methylcholanthrene results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:16619036 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mapkap1 MAPK associated protein 1 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to MAPKAP1 promoter] CTD PMID:20348232 NCBI chr 3:13,484,952...13,701,772
Ensembl chr 3:13,484,838...13,701,757
JBrowse link
G Marcks myristoylated alanine rich protein kinase C substrate decreases expression ISO Methylcholanthrene results in decreased expression of MARCKS mRNA CTD PMID:20713471 NCBI chr20:42,966,140...42,971,838
Ensembl chr20:42,966,140...42,971,838
JBrowse link
G Mastl microtubule associated serine/threonine kinase-like increases expression ISO Methylcholanthrene results in increased expression of MASTL mRNA CTD PMID:20713471 NCBI chr17:89,839,562...89,875,855
Ensembl chr17:89,742,140...89,876,825
JBrowse link
G Mat1a methionine adenosyltransferase 1A decreases expression ISO Methylcholanthrene results in decreased expression of MAT1A mRNA CTD PMID:22100608 NCBI chr16:18,690,649...18,709,135
Ensembl chr16:18,690,246...18,709,133
JBrowse link
G Matn2 matrilin 2 decreases expression ISO Methylcholanthrene results in decreased expression of MATN2 mRNA CTD PMID:20713471 NCBI chr 7:72,985,832...73,210,093
Ensembl chr 7:72,985,495...73,207,695
JBrowse link
G Mbnl1 muscleblind-like splicing regulator 1 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to MBNL1 promoter] CTD PMID:20348232 NCBI chr 2:150,698,248...150,867,791
Ensembl chr 2:150,756,185...150,869,690
JBrowse link
G Mcm10 minichromosome maintenance 10 replication initiation factor increases expression ISO Methylcholanthrene results in increased expression of MCM10 mRNA CTD PMID:20713471 NCBI chr17:77,224,218...77,245,486
Ensembl chr17:77,224,112...77,246,478
JBrowse link
G Mcm3 minichromosome maintenance complex component 3 increases expression ISO Methylcholanthrene results in increased expression of MCM3 mRNA CTD PMID:20713471 NCBI chr 9:26,914,057...26,932,201
Ensembl chr 9:26,914,057...26,932,201
JBrowse link
G Mcm4 minichromosome maintenance complex component 4 increases expression ISO Methylcholanthrene results in increased expression of MCM4 mRNA CTD PMID:20713471 NCBI chr11:89,511,191...89,524,892
Ensembl chr11:89,511,191...89,524,892
JBrowse link
G Mcm5 minichromosome maintenance complex component 5 increases expression ISO Methylcholanthrene results in increased expression of MCM5 mRNA CTD PMID:20713471 NCBI chr19:14,523,482...14,561,281
Ensembl chr19:14,523,554...14,561,278
JBrowse link
G Mcm6 minichromosome maintenance complex component 6 increases expression ISO Methylcholanthrene results in increased expression of MCM6 mRNA CTD PMID:20713471 NCBI chr13:45,042,882...45,068,073
Ensembl chr13:45,042,882...45,068,077
JBrowse link
G Med13l mediator complex subunit 13L multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to MED13L promoter] CTD PMID:20348232 NCBI chr12:43,421,317...43,576,859
Ensembl chr12:43,421,308...43,576,804
JBrowse link
G Melk maternal embryonic leucine zipper kinase increases expression ISO Methylcholanthrene results in increased expression of MELK mRNA CTD PMID:20713471 NCBI chr 5:59,783,835...59,844,356
Ensembl chr 5:59,783,890...59,844,356
JBrowse link
G Mesp1 mesoderm posterior bHLH transcription factor 1 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to MESP1 promoter] CTD PMID:20348232 NCBI chr 1:141,532,390...141,533,908
Ensembl chr 1:141,532,390...141,533,908
JBrowse link
G Mfap3l microfibril associated protein 3 like increases expression ISO Methylcholanthrene results in increased expression of MFAP3L mRNA CTD PMID:20713471 NCBI chr16:32,734,059...32,777,091
Ensembl chr16:32,738,265...32,753,278
JBrowse link
G Mgst2 microsomal glutathione S-transferase 2 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to MGST2 promoter] CTD PMID:20348232 NCBI chr 2:140,708,396...140,727,381
Ensembl chr 2:140,708,397...140,727,281
JBrowse link
G Mid1 midline 1 decreases expression ISO Methylcholanthrene results in decreased expression of MID1 mRNA CTD PMID:20713471 NCBI chr  X:25,458,782...25,839,941
Ensembl chr  X:25,458,771...25,628,272
JBrowse link
G Mideas mitotic deacetylase associated SANT domain protein multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to MIDEAS promoter] CTD PMID:20348232 NCBI chr 6:107,633,762...107,703,462
Ensembl chr 6:107,633,716...107,678,156
JBrowse link
G Mir101-2 microRNA 101-2 multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in increased expression of MIR101B mRNA CTD PMID:25926378 NCBI chr 1:247,263,723...247,263,819
Ensembl chr 1:247,263,723...247,263,819
JBrowse link
G Mir122 microRNA 122 multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in increased expression of MIR122 mRNA CTD PMID:25926378 NCBI chr18:60,755,285...60,755,369 JBrowse link
G Mir130a microRNA 130a affects expression ISO Methylcholanthrene affects the expression of MIR130A mRNA CTD PMID:25926378 NCBI chr 3:72,141,037...72,141,124
Ensembl chr 3:72,141,037...72,141,124
JBrowse link
G Mir130b microRNA 130b decreases expression ISO Methylcholanthrene results in decreased expression of MIR130B mRNA CTD PMID:25926378 NCBI chr11:88,129,773...88,129,854
Ensembl chr11:88,129,773...88,129,854
JBrowse link
G Mir144 microRNA 144 multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in increased expression of MIR144 mRNA CTD PMID:25926378 NCBI chr10:65,291,365...65,291,447
Ensembl chr10:65,291,365...65,291,447
JBrowse link
G Mir145 microRNA 145 decreases expression ISO Methylcholanthrene results in decreased expression of MIR145A mRNA CTD PMID:25926378 NCBI chr18:56,969,907...56,969,994
Ensembl chr18:56,969,907...56,969,994
JBrowse link
G Mir191 microRNA 191 multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of MIR191 mRNA CTD PMID:25926378 NCBI chr 8:117,354,364...117,354,454 JBrowse link
G Mir19a microRNA 19a multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in increased expression of MIR19A mRNA CTD PMID:25926378 NCBI chr15:100,180,162...100,180,243
Ensembl chr15:100,180,162...100,180,243
JBrowse link
G Mir206 microRNA 206 multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of MIR206 mRNA CTD PMID:25926378 NCBI chr 9:26,791,764...26,791,847
Ensembl chr 9:26,791,764...26,791,847
JBrowse link
G Mir210 microRNA 210 multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in increased expression of MIR210 mRNA CTD PMID:25926378 NCBI chr 1:214,208,355...214,208,464 JBrowse link
G Mir211 microRNA 211 decreases expression ISO Methylcholanthrene results in decreased expression of MIR211 mRNA CTD PMID:25926378 NCBI chr 1:125,042,119...125,042,224
Ensembl chr 1:125,042,119...125,042,224
JBrowse link
G Mir32 microRNA 32 decreases expression
multiple interactions
ISO Methylcholanthrene results in decreased expression of MIR32 mRNA
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of MIR32 mRNA
CTD PMID:25926378 NCBI chr 5:73,934,255...73,934,324
Ensembl chr 5:73,934,255...73,934,324
JBrowse link
G Mir345 microRNA 345 affects expression
multiple interactions
ISO Methylcholanthrene affects the expression of MIR345 mRNA
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in increased expression of MIR345 mRNA
CTD PMID:25926378 NCBI chr 6:132,748,968...132,749,063
Ensembl chr 6:132,748,968...132,749,063
JBrowse link
G Mir3545 microRNA 3545 multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of MIR203 mRNA CTD PMID:25926378 NCBI chr 6:136,704,947...136,705,061
Ensembl chr 6:136,704,947...136,705,061
JBrowse link
G Mir425 microRNA 425 decreases expression ISO Methylcholanthrene results in decreased expression of MIR425 mRNA CTD PMID:25926378 NCBI chr 8:117,354,821...117,354,903
Ensembl chr 8:117,354,821...117,354,903
JBrowse link
G Mir449a microRNA 449a multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of MIR449A mRNA CTD PMID:25926378 NCBI chr 2:44,897,601...44,897,691
Ensembl chr 2:44,897,601...44,897,691
JBrowse link
G Mir497 microRNA 497 increases expression ISO Methylcholanthrene results in increased expression of MIR497 mRNA CTD PMID:25926378 NCBI chr10:56,844,977...56,845,045
Ensembl chr10:56,844,977...56,845,045
JBrowse link
G Mir92a2 microRNA 92a-2 decreases expression ISO Methylcholanthrene results in decreased expression of MIR92-2 mRNA CTD PMID:25926378 NCBI chr  X:140,117,249...140,117,340
Ensembl chr  X:140,117,249...140,117,340
JBrowse link
G Mki67 marker of proliferation Ki-67 increases expression
multiple interactions
ISO
EXP
Methylcholanthrene results in increased expression of MKI67 mRNA
Methylcholanthrene inhibits the reaction [Estradiol results in increased expression of MKI67 mRNA]; Methylcholanthrene inhibits the reaction [Estradiol results in increased expression of MKI67 protein]
CTD PMID:20713471, PMID:26372666 NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454
JBrowse link
G Mllt6 MLLT6, PHD finger containing multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to MLLT6 promoter] CTD PMID:20348232 NCBI chr10:85,607,988...85,628,171
Ensembl chr10:85,608,544...85,625,854
JBrowse link
G Mlph melanophilin multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to MLPH promoter] CTD PMID:20348232 NCBI chr 9:98,072,965...98,108,429
Ensembl chr 9:98,073,038...98,108,433
JBrowse link
G Mmp1 matrix metallopeptidase 1 increases expression ISO Methylcholanthrene results in increased expression of MMP1 mRNA CTD PMID:29554273 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Mmp13 matrix metallopeptidase 13 increases expression
decreases expression
ISO Methylcholanthrene results in increased expression of MMP13 mRNA
Methylcholanthrene results in decreased expression of MMP13 mRNA
CTD PMID:20713471, PMID:29554273 NCBI chr 8:5,522,739...5,533,018
Ensembl chr 8:5,522,739...5,533,018
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions EXP [Methylcholanthrene co-treated with Diethylnitrosamine] results in increased expression of MMP2 mRNA; [Methylcholanthrene co-treated with Diethylnitrosamine] results in increased expression of MMP2 protein CTD PMID:12015029 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp3 matrix metallopeptidase 3 increases expression ISO Methylcholanthrene results in increased expression of MMP3 mRNA CTD PMID:20713471 NCBI chr 8:5,676,608...5,698,579
Ensembl chr 8:5,676,665...5,698,579
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
decreases expression
ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of MMP9 mRNA
Methylcholanthrene results in decreased expression of MMP9 mRNA
CTD PMID:23519560, PMID:29554273 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mpi mannose phosphate isomerase multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to MPI promoter] CTD PMID:20348232 NCBI chr 8:62,324,176...62,332,080
Ensembl chr 8:62,324,092...62,332,115
JBrowse link
G Mpl MPL proto-oncogene, thrombopoietin receptor multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of MPL mRNA CTD PMID:25926378 NCBI chr 5:137,268,412...137,282,032
Ensembl chr 5:137,269,480...137,281,298
JBrowse link
G Mpp6 membrane palmitoylated protein 6 increases expression ISO Methylcholanthrene results in increased expression of MPP6 mRNA CTD PMID:20713471 NCBI chr 4:79,846,506...79,928,977
Ensembl chr 4:79,846,521...79,926,703
JBrowse link
G Mrtfb myocardin related transcription factor B multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to MRTFB promoter] CTD PMID:20348232 NCBI chr10:1,151,163...1,273,269 JBrowse link
G Ms4a7 membrane spanning 4-domains A7 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to MS4A7 promoter] CTD PMID:20348232 NCBI chr 1:227,490,777...227,506,819
Ensembl chr 1:227,490,777...227,506,822
JBrowse link
G Msln mesothelin increases expression ISO Methylcholanthrene results in increased expression of MSLN mRNA CTD PMID:20713471 NCBI chr10:15,119,700...15,129,129
Ensembl chr10:15,119,663...15,125,408
JBrowse link
G Msmb microseminoprotein, beta multiple interactions
affects binding
increases expression
ISO
EXP
Methylcholanthrene promotes the reaction [AHR protein binds to MSMB promoter]
Methylcholanthrene binds to MSMB protein
Methylcholanthrene results in increased expression of MSMB mRNA
CTD PMID:3940634, PMID:20348232 NCBI chr16:8,280,275...8,300,853
Ensembl chr16:8,280,275...8,300,852
JBrowse link
G Msmo1 methylsterol monooxygenase 1 decreases expression ISO Methylcholanthrene results in decreased expression of MSMO1 mRNA CTD PMID:20713471 NCBI chr16:26,859,441...26,875,880
Ensembl chr16:26,859,397...26,875,973
JBrowse link
G Mt2A metallothionein 2A multiple interactions
increases expression
ISO AHR protein affects the reaction [Methylcholanthrene results in increased expression of MT2A mRNA]; Dexamethasone promotes the reaction [Methylcholanthrene results in increased expression of MT2A mRNA]; Methylcholanthrene promotes the reaction [Dexamethasone results in increased expression of MT2A mRNA]; NR3C1 protein affects the reaction [Dexamethasone promotes the reaction [Methylcholanthrene results in increased expression of MT2A mRNA]]; NR3C1 protein affects the reaction [Methylcholanthrene promotes the reaction [Dexamethasone results in increased expression of MT2A mRNA]]; NR3C1 protein affects the reaction [Methylcholanthrene results in increased expression of MT2A mRNA] CTD PMID:23994556 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in increased expression of MTHFD2 mRNA CTD PMID:25926378 NCBI chr 4:115,004,433...115,015,965
Ensembl chr 4:115,004,448...115,015,965
JBrowse link
G Myh7 myosin heavy chain 7 multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in increased expression of MYH7 mRNA CTD PMID:25926378 NCBI chr15:33,605,769...33,657,761
Ensembl chr15:33,634,422...33,656,089
JBrowse link
G Myl9 myosin light chain 9 decreases expression
multiple interactions
ISO Methylcholanthrene results in decreased expression of MYL9 mRNA
[Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of MYL9 mRNA
CTD PMID:20713471, PMID:25926378 NCBI chr 3:152,857,573...152,863,961
Ensembl chr 3:152,857,592...152,863,960
JBrowse link
G Mylk myosin light chain kinase multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of MYLK mRNA CTD PMID:23519560 NCBI chr11:69,013,060...69,260,039
Ensembl chr11:69,013,050...69,223,158
JBrowse link
G Myo1d myosin ID decreases expression ISO Methylcholanthrene results in decreased expression of MYO1D mRNA CTD PMID:20713471 NCBI chr10:67,866,939...68,142,864
Ensembl chr10:67,866,940...68,142,864
JBrowse link
G Myo7a myosin VIIA decreases expression ISO Methylcholanthrene results in decreased expression of MYO7A mRNA CTD PMID:20713471 NCBI chr 1:163,001,313...163,071,545
Ensembl chr 1:163,001,875...163,071,508
JBrowse link
G Myof myoferlin multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to MYOF promoter] CTD PMID:20348232 NCBI chr 1:256,585,410...256,734,727
Ensembl chr 1:256,585,410...256,734,730
JBrowse link
G Myom2 myomesin 2 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to MYOM2 promoter] CTD PMID:20348232 NCBI chr16:79,587,136...79,672,871
Ensembl chr16:79,587,640...79,671,719
JBrowse link
G Nasp nuclear autoantigenic sperm protein increases expression ISO Methylcholanthrene results in increased expression of NASP mRNA CTD PMID:20713471 NCBI chr 5:135,446,485...135,472,113
Ensembl chr 5:135,446,962...135,472,116
JBrowse link
G Ncam1 neural cell adhesion molecule 1 decreases expression ISO Methylcholanthrene results in decreased expression of NCAM1 mRNA CTD PMID:20713471 NCBI chr 8:53,836,797...54,134,881
Ensembl chr 8:53,839,098...53,901,358
JBrowse link
G Ncapg2 non-SMC condensin II complex, subunit G2 increases expression ISO Methylcholanthrene results in increased expression of NCAPG2 mRNA CTD PMID:20713471 NCBI chr 6:144,291,313...144,362,454
Ensembl chr 6:144,291,974...144,363,947
JBrowse link
G Ncaph non-SMC condensin I complex, subunit H increases expression ISO Methylcholanthrene results in increased expression of NCAPH mRNA CTD PMID:20713471 NCBI chr 3:119,583,798...119,611,148
Ensembl chr 3:119,583,648...119,611,136
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 increases expression ISO Methylcholanthrene results in increased expression of NCF1 mRNA CTD PMID:19559082 NCBI chr12:25,497,104...25,506,300
Ensembl chr12:25,497,104...25,506,300
JBrowse link
G Nck2 NCK adaptor protein 2 decreases expression ISO Methylcholanthrene results in decreased expression of NCK2 mRNA CTD PMID:20713471 NCBI chr 9:50,246,767...50,373,307
Ensembl chr 9:50,247,692...50,373,284
JBrowse link
G Ndc80 NDC80 kinetochore complex component decreases expression
increases expression
ISO Methylcholanthrene results in decreased expression of NDC80 mRNA
Methylcholanthrene results in increased expression of NDC80 mRNA
CTD PMID:20713471, PMID:22579512 NCBI chr 9:119,837,857...119,871,435
Ensembl chr 9:119,839,016...119,871,382
JBrowse link
G Ndrg4 NDRG family member 4 increases expression ISO Methylcholanthrene results in increased expression of NDRG4 mRNA CTD PMID:20713471 NCBI chr19:9,766,439...9,802,396
Ensembl chr19:9,766,439...9,801,942
JBrowse link
G Ndst1 N-deacetylase and N-sulfotransferase 1 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to NDST1 promoter] CTD PMID:20348232 NCBI chr18:55,951,497...56,014,107
Ensembl chr18:55,955,389...55,992,885
JBrowse link
G Nedd9 neural precursor cell expressed, developmentally down-regulated 9 increases expression ISO Methylcholanthrene results in increased expression of NEDD9 mRNA CTD PMID:16619036 NCBI chr17:22,984,792...23,179,701
Ensembl chr17:22,984,844...23,179,701
JBrowse link
G Nek2 NIMA-related kinase 2 increases expression ISO Methylcholanthrene results in increased expression of NEK2 mRNA CTD PMID:20713471 NCBI chr13:110,511,546...110,524,750
Ensembl chr13:110,511,668...110,522,769
JBrowse link
G Nelfcd negative elongation factor complex member C/D multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to NELFCD promoter] CTD PMID:20348232 NCBI chr 3:172,510,840...172,527,118
Ensembl chr 3:172,510,874...172,526,740
JBrowse link
G Nfatc2 nuclear factor of activated T-cells 2 decreases expression ISO Methylcholanthrene results in decreased expression of NFATC2 mRNA CTD PMID:29554273 NCBI chr 3:165,241,750...165,374,644
Ensembl chr 3:165,245,238...165,360,292
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases expression
multiple interactions
ISO Methylcholanthrene results in increased expression of NFE2L2 mRNA; Methylcholanthrene results in increased expression of NFE2L2 protein
Methylcholanthrene promotes the reaction [AHR protein binds to NFE2L2 promoter]
NFE2L2 protein affects the reaction [Methylcholanthrene results in increased expression of PSMB5 mRNA]
CTD PMID:16723119, PMID:20348232, PMID:20713471, PMID:23712962 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkbia NFKB inhibitor alpha increases expression ISO Methylcholanthrene results in increased expression of NFKBIA mRNA CTD PMID:29554273 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nfkbiz NFKB inhibitor zeta increases expression ISO Methylcholanthrene results in increased expression of NFKBIZ mRNA CTD PMID:20713471 NCBI chr11:47,243,342...47,271,487
Ensembl chr11:47,243,342...47,271,487
JBrowse link
G Nfya nuclear transcription factor Y subunit alpha multiple interactions
increases activity
ISO Methylcholanthrene promotes the reaction [NFYA protein binds to KRAS exon]
Methylcholanthrene results in increased activity of NFYA protein
CTD PMID:16271038 NCBI chr 9:14,551,752...14,577,002
Ensembl chr 9:14,551,758...14,576,967
JBrowse link
G Ngf nerve growth factor increases expression
multiple interactions
ISO Methylcholanthrene results in increased expression of NGF mRNA
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of NGF mRNA
CTD PMID:20713471, PMID:23519560 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453
JBrowse link
G Niban1 niban apoptosis regulator 1 increases expression ISO Methylcholanthrene results in increased expression of NIBAN1 mRNA CTD PMID:20713471 NCBI chr13:68,949,665...69,101,600
Ensembl chr13:68,949,665...69,101,588
JBrowse link
G Nkd2 NKD inhibitor of WNT signaling pathway 2 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of NKD2 mRNA CTD PMID:23519560 NCBI chr 1:32,054,390...32,085,416
Ensembl chr 1:32,058,044...32,084,877
JBrowse link
G Nmral1 NmrA like redox sensor 1 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to NMRAL1 promoter] CTD PMID:20348232 NCBI chr10:11,045,924...11,055,154
Ensembl chr10:11,046,024...11,055,158
JBrowse link
G Nop58 NOP58 ribonucleoprotein increases expression ISO Methylcholanthrene results in increased expression of NOL5 mRNA CTD PMID:20713471 NCBI chr 9:66,495,881...66,520,521
Ensembl chr 9:66,495,832...66,519,788
JBrowse link
G Notch2 notch receptor 2 decreases acetylation
increases methylation
increases expression
multiple interactions
EXP Methylcholanthrene results in decreased acetylation of NOTCH2 promoter
Methylcholanthrene results in increased methylation of NOTCH2 promoter
Methylcholanthrene results in increased expression of NOTCH2 mRNA
alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in decreased acetylation of NOTCH2 promoter]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased expression of NOTCH2 mRNA]; alpha-naphthoflavone inhibits the reaction [Methylcholanthrene results in increased methylation of NOTCH2 promoter]
CTD PMID:29094188 NCBI chr 2:200,187,184...200,320,403
Ensembl chr 2:200,187,179...200,320,215
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions
increases expression
increases activity
ISO
EXP
Arsenic promotes the reaction [Methylcholanthrene results in increased expression of NQO1 mRNA]; Cadmium promotes the reaction [Methylcholanthrene results in increased expression of NQO1 mRNA]; Chromium inhibits the reaction [Methylcholanthrene results in increased activity of NQO1 protein]; Chromium inhibits the reaction [Methylcholanthrene results in increased expression of NQO1 mRNA]
Methylcholanthrene results in increased expression of NQO1 mRNA; Methylcholanthrene results in increased expression of NQO1 protein
[protocatechuic acid co-treated with Methylcholanthrene] results in increased activity of NQO1 protein; Buthionine Sulfoximine promotes the reaction [Methylcholanthrene results in increased activity of NQO1 protein]; Ethoxyquin promotes the reaction [Methylcholanthrene results in increased activity of NQO1 protein]; Methylcholanthrene promotes the reaction [Buthionine Sulfoximine results in increased activity of NQO1 protein]; Methylcholanthrene promotes the reaction [Ethoxyquin results in increased activity of NQO1 protein]; Methylcholanthrene results in increased expression of and results in increased activity of NQO1 protein
CTD PMID:4005852, PMID:11323195, PMID:12206817, PMID:15302093, PMID:15337587, PMID:16906435, PMID:17069994, PMID:17253728, PMID:18203689, PMID:20713471, PMID:23273579, PMID:23712962 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nqo2 N-ribosyldihydronicotinamide:quinone reductase 2 increases expression ISO Methylcholanthrene results in increased expression of NQO2 mRNA CTD PMID:20713471 NCBI chr17:32,131,847...32,158,559
Ensembl chr17:32,132,347...32,158,538
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 increases expression ISO Methylcholanthrene results in increased expression of NR0B2 mRNA CTD PMID:19118567 NCBI chr 5:151,776,004...151,779,319
Ensembl chr 5:151,776,004...151,779,319
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 increases expression EXP Methylcholanthrene results in increased expression of NR1H3 mRNA CTD PMID:23273579 NCBI chr 3:80,004,130...80,014,197
Ensembl chr 3:80,004,130...80,012,750
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases expression
affects expression
ISO
EXP
Methylcholanthrene results in increased expression of NR1I3 mRNA
Methylcholanthrene affects the expression of NR1I3 mRNA
CTD PMID:19118567, PMID:23273579 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 decreases expression
multiple interactions
EXP
ISO
Methylcholanthrene results in decreased expression of NR3C1 protein
[NR3C1 protein co-treated with Dexamethasone] inhibits the reaction [Methylcholanthrene results in increased expression of CYP1A1 mRNA]; [NR3C1 protein co-treated with Dexamethasone] results in decreased susceptibility to Methylcholanthrene; NR3C1 protein affects the reaction [Dexamethasone promotes the reaction [Methylcholanthrene results in increased expression of MT2A mRNA]]; NR3C1 protein affects the reaction [Methylcholanthrene promotes the reaction [Dexamethasone results in increased expression of MT2A mRNA]]; NR3C1 protein affects the reaction [Methylcholanthrene results in increased expression of MT2A mRNA]
CTD PMID:1638671, PMID:23994556, PMID:24091107 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 decreases expression ISO Methylcholanthrene results in decreased expression of NR4A1 mRNA CTD PMID:20713471 NCBI chr 7:142,899,358...142,920,216
Ensembl chr 7:142,905,758...142,920,216
JBrowse link
G Nrep neuronal regeneration related protein decreases expression ISO Methylcholanthrene results in decreased expression of NREP mRNA CTD PMID:20713471 NCBI chr18:26,183,753...26,212,796
Ensembl chr18:26,185,259...26,211,445
JBrowse link
G Nrn1 neuritin 1 increases expression ISO Methylcholanthrene results in increased expression of NRN1 mRNA CTD PMID:20713471 NCBI chr17:27,925,054...28,002,946
Ensembl chr17:27,925,057...27,969,433
JBrowse link
G Nrxn2 neurexin 2 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of NRXN2 mRNA CTD PMID:23519560 NCBI chr 1:221,792,191...221,908,047
Ensembl chr 1:221,792,221...221,908,049
JBrowse link
G Nsdhl NAD(P) dependent steroid dehydrogenase-like decreases expression ISO Methylcholanthrene results in decreased expression of NSDHL mRNA CTD PMID:20713471 NCBI chr  X:152,933,118...152,964,399
Ensembl chr  X:152,933,069...152,964,390
JBrowse link
G Nudt21 nudix hydrolase 21 increases expression ISO Methylcholanthrene results in increased expression of NUDT21 mRNA CTD PMID:20713471 NCBI chr19:11,451,366...11,470,637
Ensembl chr19:11,450,760...11,467,644
JBrowse link
G Nusap1 nucleolar and spindle associated protein 1 increases expression ISO Methylcholanthrene results in increased expression of NUSAP1 mRNA CTD PMID:20713471 NCBI chr 3:111,422,267...111,452,600
Ensembl chr 3:111,422,267...111,452,971
JBrowse link
G Nxn nucleoredoxin decreases expression ISO Methylcholanthrene results in decreased expression of NXN mRNA CTD PMID:29554273 NCBI chr10:64,411,710...64,550,147
Ensembl chr10:64,412,833...64,550,145
JBrowse link
G Nxt2 nuclear transport factor 2-like export factor 2 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to NXT2 promoter] CTD PMID:20348232 NCBI chr  X:113,509,841...113,517,112
Ensembl chr  X:113,510,621...113,517,102
JBrowse link
G Ogn osteoglycin decreases expression ISO Methylcholanthrene results in decreased expression of OGN mRNA CTD PMID:20713471 NCBI chr17:14,607,442...14,628,274
Ensembl chr17:15,447,716...15,467,359
Ensembl chr17:15,447,716...15,467,359
JBrowse link
G Oip5 Opa interacting protein 5 increases expression ISO Methylcholanthrene results in increased expression of OIP5 mRNA CTD PMID:20713471 NCBI chr 3:111,413,662...111,422,320
Ensembl chr 3:111,416,536...111,422,203
JBrowse link
G Olfm1 olfactomedin 1 increases expression ISO Methylcholanthrene results in increased expression of OLFM1 mRNA CTD PMID:20713471 NCBI chr 3:6,761,031...6,798,739
Ensembl chr 3:6,773,813...6,798,737
JBrowse link
G Olr1339 olfactory receptor 1339 multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in increased expression of OLFR984 mRNA CTD PMID:25926378 NCBI chr 8:43,919,476...43,920,420
Ensembl chr 8:43,919,476...43,920,420
JBrowse link
G Olr1635 olfactory receptor 1635 decreases expression ISO Methylcholanthrene results in decreased expression of OLFR749 mRNA CTD PMID:25926378 NCBI chr15:27,548,762...27,549,748
Ensembl chr15:27,548,762...27,549,748
JBrowse link
G Olr1637 olfactory receptor 1637 decreases expression ISO Methylcholanthrene results in decreased expression of OLFR750 mRNA CTD PMID:25926378 NCBI chr15:27,996,520...27,999,286
Ensembl chr15:27,996,815...27,997,810
JBrowse link
G Osbpl10 oxysterol binding protein-like 10 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to OSBPL10 promoter] CTD PMID:20348232 NCBI chr 8:123,029,722...123,303,553
Ensembl chr 8:123,126,667...123,293,562
JBrowse link
G Osr2 odd-skipped related transciption factor 2 decreases expression ISO Methylcholanthrene results in decreased expression of OSR2 mRNA CTD PMID:20713471 NCBI chr 7:74,047,820...74,055,096
Ensembl chr 7:74,047,814...74,055,256
JBrowse link
G Otub2 OTU deubiquitinase, ubiquitin aldehyde binding 2 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to OTUB2 promoter] CTD PMID:20348232 NCBI chr 6:127,282,445...127,301,086
Ensembl chr 6:127,282,466...127,301,083
JBrowse link
G Otulinl OTU deubiquitinase with linear linkage specificity like increases expression ISO Methylcholanthrene results in increased expression of OTULINL mRNA CTD PMID:25926378 NCBI chr 2:80,383,642...80,408,672
Ensembl chr 2:80,383,643...80,408,672
JBrowse link
G P2rx7 purinergic receptor P2X 7 decreases expression
multiple interactions
ISO Methylcholanthrene results in decreased expression of P2RX7 mRNA
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of P2RX7 mRNA
CTD PMID:20713471, PMID:23519560 NCBI chr12:39,353,613...39,396,042
Ensembl chr12:39,353,613...39,396,042
JBrowse link
G P2ry1 purinergic receptor P2Y1 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of P2RY1 mRNA CTD PMID:23519560 NCBI chr 2:151,314,818...151,320,312
Ensembl chr 2:151,314,818...151,320,319
JBrowse link
G Pah phenylalanine hydroxylase decreases expression ISO Methylcholanthrene results in decreased expression of PAH mRNA CTD PMID:22579512 NCBI chr 7:28,066,639...28,129,772
Ensembl chr 7:28,066,635...28,129,769
JBrowse link
G Pak6 p21 (RAC1) activated kinase 6 multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PAK6 mRNA CTD PMID:23519560 NCBI chr 3:110,442,175...110,486,317
Ensembl chr 3:110,442,637...110,487,526
JBrowse link
G Pard6b par-6 family cell polarity regulator beta decreases expression
multiple interactions
ISO Methylcholanthrene results in decreased expression of PARD6B mRNA
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PARD6B mRNA
CTD PMID:20713471, PMID:23519560 NCBI chr 3:164,822,111...164,843,395
Ensembl chr 3:164,822,111...164,843,395
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions EXP Methylcholanthrene inhibits the reaction [3-amino-1,4-dimethyl-5H-pyrido(4,3-b)indole results in increased cleavage of PARP1 protein] CTD PMID:11999409 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Paxbp1 PAX3 and PAX7 binding protein 1 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to PAXBP1 promoter] CTD PMID:20348232 NCBI chr11:31,184,456...31,213,891
Ensembl chr11:31,185,473...31,213,787
JBrowse link
G Pbk PDZ binding kinase increases expression ISO Methylcholanthrene results in increased expression of PBK mRNA CTD PMID:20713471 NCBI chr15:42,489,253...42,500,377
Ensembl chr15:42,489,377...42,500,395
JBrowse link
G Pcdh18 protocadherin 18 decreases expression ISO Methylcholanthrene results in decreased expression of PCDH18 mRNA CTD PMID:20713471 NCBI chr 2:138,819,957...138,833,932
Ensembl chr 2:138,819,960...138,833,933
JBrowse link
G Pcdh7 protocadherin 7 decreases expression ISO Methylcholanthrene results in decreased expression of PCDH7 mRNA CTD PMID:20713471 NCBI chr14:54,649,054...55,081,632
Ensembl chr14:55,072,200...55,081,551
JBrowse link
G Pcdhb3 protocadherin beta 3 decreases expression ISO Methylcholanthrene results in decreased expression of PCDHB9 mRNA CTD PMID:20713471 NCBI chr18:30,381,322...30,383,876
Ensembl chr18:30,381,322...30,383,876
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 decreases expression EXP Methylcholanthrene results in decreased expression of PCK1 mRNA CTD PMID:11328961 NCBI chr 3:171,213,936...171,219,885
Ensembl chr 3:171,213,936...171,219,871
JBrowse link
G PCOLCE2 procollagen C-endopeptidase enhancer 2 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to PCOLCE2 promoter] CTD PMID:20348232 NCBI chr 8:103,459,219...103,484,557
Ensembl chr 8:103,459,161...103,484,535
JBrowse link
G Pdcd4 programmed cell death 4 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to PDCD4 promoter] CTD PMID:20348232 NCBI chr 1:274,616,625...274,648,204
Ensembl chr 1:274,625,224...274,648,204
JBrowse link
G Pde1b phosphodiesterase 1B multiple interactions ISO [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PDE1B mRNA CTD PMID:23519560 NCBI chr 7:145,117,951...145,147,711
Ensembl chr 7:145,117,951...145,145,376
JBrowse link
G Pdlim5 PDZ and LIM domain 5 decreases expression ISO Methylcholanthrene results in decreased expression of PDLIM5 mRNA CTD PMID:20713471 NCBI chr 2:247,815,214...247,989,198
Ensembl chr 2:247,818,243...247,988,462
JBrowse link
G Pdzd8 PDZ domain containing 8 increases expression ISO Methylcholanthrene results in increased expression of PDZD8 mRNA CTD PMID:25926378 NCBI chr 1:280,458,041...280,515,650
Ensembl chr 1:280,458,041...280,515,650
JBrowse link
G Peli2 pellino E3 ubiquitin protein ligase family member 2 increases expression ISO Methylcholanthrene results in increased expression of PELI2 mRNA CTD PMID:20713471 NCBI chr15:24,942,218...25,086,350
Ensembl chr15:24,942,218...25,083,931
JBrowse link
G Pf4 platelet factor 4 multiple interactions ISO [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of PF4 mRNA CTD PMID:25926378 NCBI chr14:18,848,549...18,849,258
Ensembl chr14:18,848,549...18,849,258
JBrowse link
G Pgr progesterone receptor increases expression
multiple interactions
ISO
EXP
Methylcholanthrene results in increased expression of PGR mRNA
Methylcholanthrene inhibits the reaction [Estradiol results in increased expression of PGR mRNA]; Methylcholanthrene inhibits the reaction [Estradiol results in increased expression of PGR protein]
CTD PMID:16257430, PMID:26372666 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Phactr1 phosphatase and actin regulator 1 multiple interactions ISO Methylcholanthrene promotes the reaction [AHR protein binds to PHACTR1 promoter] CTD PMID:20348232 NCBI chr17:23,245,423...23,761,207