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Accession:CHEBI:3504 term browser browse the term
Definition:A third-generation cephalosporin antibiotic with methoxymethyl and (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamino substituents at positions 3 and 7, respectively, of the cephem skeleton. Given by mouth as its proxetil ester prodrug, it is used to treat acute otitis media, pharyngitis, and sinusitis.
Synonyms:exact_synonym: 7beta-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-(methoxymethyl)-3,4-didehydrocepham-4-carboxylic acid
 related_synonym: (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;   Formula=C15H17N5O6S2;   InChI=1S/C15H17N5O6S2/c1-25-3-6-4-27-13-9(12(22)20(13)10(6)14(23)24)18-11(21)8(19-26-2)7-5-28-15(16)17-7/h5,9,13H,3-4H2,1-2H3,(H2,16,17)(H,18,21)(H,23,24)/b19-8-/t9-,13-/m1/s1;   InChIKey=WYUSVOMTXWRGEK-HBWVYFAYSA-N;   SMILES=[H][C@]12SCC(COC)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\\c1csc(N)n1)C(O)=O;   cefpodoxima;   cefpodoximum
 alt_id: CHEBI:606443
 xref: Beilstein:6021381 "Beilstein";   CAS:80210-62-4 "ChemIDplus";   CAS:80210-62-4 "KEGG COMPOUND";   DrugBank:DB01416;   KEGG:C08114;   KEGG:D07650
 xref_mesh: MESH:C053268
 xref: PMID:20606336 "Europe PMC";   PMID:20821175 "Europe PMC";   PMID:21395603 "Europe PMC";   PMID:21420838 "Europe PMC";   PMID:21455420 "Europe PMC";   PMID:21509928 "Europe PMC";   PMID:21569093 "Europe PMC";   PMID:21667000 "Europe PMC";   PMID:29017833 "Europe PMC";   Reaxys:6021381 "Reaxys";   VSDB:2968;   Wikipedia:Cefpodoxime

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cefpodoxime term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Prl prolactin JBrowse link 17 39,814,236 39,824,299 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19728
    role 19675
      biological role 19673
        antimicrobial agent 17211
          antibacterial agent 12926
            antibacterial drug 3089
              cefpodoxime 1
                cefpodoxime proxetil 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19728
    subatomic particle 19724
      composite particle 19724
        hadron 19724
          baryon 19724
            nucleon 19724
              atomic nucleus 19724
                atom 19724
                  main group element atom 19610
                    p-block element atom 19610
                      carbon group element atom 19501
                        carbon atom 19494
                          organic molecular entity 19494
                            organic group 18413
                              organic divalent group 18404
                                organodiyl group 18404
                                  carbonyl group 18293
                                    carbonyl compound 18293
                                      carboxylic acid 17960
                                        carboacyl group 17072
                                          univalent carboacyl group 17072
                                            carbamoyl group 16801
                                              carboxamide 16801
                                                lactam 7814
                                                  beta-lactam 784
                                                    beta-lactam antibiotic 772
                                                      cephem 537
                                                        cephalosporin 536
                                                          cefpodoxime 1
                                                            cefpodoxime proxetil 0
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.