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Accession:CHEBI:3508 term browser browse the term
Definition:A third-generation cephalosporin antibiotic bearing pyridinium-1-ylmethyl and {[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetamido groups at positions 3 and 7, respectively, of the cephem skeleton.
Synonyms:exact_synonym: 7beta-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-3-(pyridinium-1-ylmethyl)-3,4-didehydrocepham-4-carboxylate
 related_synonym: (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-3-(pyridinium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate;   CAZ;   Ceftazidime anhydrous;   Formula=C22H22N6O7S2;   InChI=1S/C22H22N6O7S2/c1-22(2,20(33)34)35-26-13(12-10-37-21(23)24-12)16(29)25-14-17(30)28-15(19(31)32)11(9-36-18(14)28)8-27-6-4-3-5-7-27/h3-7,10,14,18H,8-9H2,1-2H3,(H4-,23,24,25,29,31,32,33,34)/b26-13-/t14-,18-/m1/s1;   InChIKey=ORFOPKXBNMVMKC-DWVKKRMSSA-N;   SMILES=[H][C@]12SCC(C[n+]3ccccc3)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC(C)(C)C(O)=O)\\c1csc(N)n1)C([O-])=O;   ceftazidima;   ceftazidimum
 xref: Beilstein:5475149 "Beilstein";   CAS:72558-82-8 "ChemIDplus";   CAS:72558-82-8 "KEGG COMPOUND";   CAS:72558-82-8 "KEGG DRUG";   DrugBank:DB00438;   KEGG:C06889;   KEGG:D07654;   PMID:11252323 "Europe PMC";   PMID:11284241 "Europe PMC";   PMID:11591698 "Europe PMC";   PMID:11605815 "Europe PMC";   PMID:11815759 "Europe PMC";   PMID:12048030 "Europe PMC";   PMID:12120880 "Europe PMC";   PMID:12523657 "Europe PMC";   PMID:12767750 "Europe PMC";   PMID:12833570 "Europe PMC";   PMID:1384868 "Europe PMC";   PMID:14961139 "Europe PMC";   PMID:15528892 "Europe PMC";   PMID:15618675 "Europe PMC";   PMID:15687217 "Europe PMC";   PMID:15913752 "Europe PMC";   PMID:16092041 "Europe PMC";   PMID:16501927 "Europe PMC";   PMID:16956383 "Europe PMC";   PMID:18611568 "Europe PMC";   PMID:18926104 "Europe PMC";   PMID:19810175 "Europe PMC";   PMID:1991925 "Europe PMC";   PMID:2068466 "Europe PMC";   PMID:24089577 "Europe PMC";   PMID:2570956 "Europe PMC";   PMID:28543395 "Europe PMC";   Patent:DE2921316;   Patent:US4258041;   Reaxys:5475149 "Reaxys";   Wikipedia:Ceftazidime
 cyclic_relationship: is_conjugate_acid_of CHEBI:53676

show annotations for term's descendants       view all columns           Sort by:
ceftazidime pentahydrate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcc4 ATP binding cassette subfamily C member 4 JBrowse link 15 103,695,415 103,927,980 RGD:6480464
G Dhfr dihydrofolate reductase JBrowse link 2 21,931,887 21,958,927 RGD:6480464
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19728
    role 19675
      biological role 19673
        antimicrobial agent 17211
          antibacterial agent 12926
            antibacterial drug 3089
              ceftazidime 3
                ceftazidime pentahydrate + 3
                ceftazidime sodium 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19728
    subatomic particle 19724
      composite particle 19724
        hadron 19724
          baryon 19724
            nucleon 19724
              atomic nucleus 19724
                atom 19724
                  main group element atom 19610
                    p-block element atom 19610
                      carbon group element atom 19501
                        carbon atom 19494
                          organic molecular entity 19494
                            organic group 18413
                              organic divalent group 18404
                                organodiyl group 18404
                                  carbonyl group 18293
                                    carbonyl compound 18293
                                      carboxylic acid 17960
                                        carboacyl group 17072
                                          univalent carboacyl group 17072
                                            carbamoyl group 16801
                                              carboxamide 16801
                                                lactam 7814
                                                  beta-lactam 784
                                                    beta-lactam antibiotic 772
                                                      cephem 537
                                                        cephalosporin 536
                                                          ceftazidime 3
                                                            ceftazidime pentahydrate + 3
                                                            ceftazidime sodium 0
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.