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Accession:CHEBI:3515 term browser browse the term
Definition:A 3-(carbamoyloxymethyl)cephalosporin compound having a 7-(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido side chain.
Synonyms:exact_synonym: 3-[(carbamoyloxy)methyl]-7beta-[(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido]-3,4-didehydrocepham-4-carboxylic acid
 related_synonym: (6R,7R)-3-[(carbamoyloxy)methyl]-7-{[(2Z)-2-furan-2-yl-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;   Cefuroxim;   Cephuroxime;   Formula=C16H16N4O8S;   InChI=1S/C16H16N4O8S/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24)/b19-9-/t10-,14-/m1/s1;   InChIKey=JFPVXVDWJQMJEE-IZRZKJBUSA-N;   SMILES=[H][C@]12SCC(COC(N)=O)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\\c1ccco1)C(O)=O;   Sharox;   Zinacef Danmark;   cefuroximo;   cefuroximum
 xref: CAS:55268-75-2 "ChemIDplus";   CAS:55268-75-2 "KEGG COMPOUND";   DrugBank:DB01112;   Drug_Central:565 "DrugCentral";   KEGG:C06894;   KEGG:D00262
 xref_mesh: MESH:D002444
 xref: MetaCyc:CPD0-2069;   PMID:11168076 "Europe PMC";   PMID:11322179 "Europe PMC";   PMID:11581233 "Europe PMC";   PMID:12141712 "Europe PMC";   PMID:12235459 "Europe PMC";   PMID:12833570 "Europe PMC";   PMID:12898829 "Europe PMC";   PMID:14658923 "Europe PMC";   PMID:15052582 "Europe PMC";   PMID:15828440 "Europe PMC";   PMID:16341950 "Europe PMC";   PMID:17111749 "Europe PMC";   PMID:17113884 "Europe PMC";   PMID:17261579 "Europe PMC";   PMID:17366015 "Europe PMC";   PMID:17676080 "Europe PMC";   PMID:18208759 "Europe PMC";   PMID:18611587 "Europe PMC";   PMID:18795089 "Europe PMC";   PMID:18931469 "Europe PMC";   PMID:19069618 "Europe PMC";   PMID:19142482 "Europe PMC";   PMID:19411164 "Europe PMC";   PMID:21425867 "Europe PMC";   PMID:29017833 "Europe PMC";   Patent:DE2439880;   Patent:DE2706413;   Patent:US3974153;   Patent:US4267320;   Reaxys:5783190 "Reaxys";   Wikipedia:Cefuroxime

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cefuroxime term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:6480464
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:6480464
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:6480464
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 JBrowse link 13 89,585,072 89,591,278 RGD:6480464
G Ppara peroxisome proliferator activated receptor alpha JBrowse link 7 126,618,872 126,687,282 RGD:6480464
G RT1-Bb RT1 class II, locus Bb JBrowse link 20 4,043,726 4,049,367 RGD:6480464
G RT1-S3 RT1 class Ib, locus S3 JBrowse link 20 3,176,124 3,180,825 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19728
    role 19675
      application 19328
        pharmaceutical 19202
          drug 19202
            drug allergen 9754
              cefuroxime 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 19728
    subatomic particle 19724
      composite particle 19724
        hadron 19724
          baryon 19724
            nucleon 19724
              atomic nucleus 19724
                atom 19724
                  main group element atom 19610
                    p-block element atom 19610
                      carbon group element atom 19501
                        carbon atom 19494
                          organic molecular entity 19494
                            organic group 18413
                              organic divalent group 18404
                                organodiyl group 18404
                                  carbonyl group 18293
                                    carbonyl compound 18293
                                      carboxylic acid 17960
                                        carboacyl group 17072
                                          univalent carboacyl group 17072
                                            carbamoyl group 16801
                                              carboxamide 16801
                                                lactam 7814
                                                  beta-lactam 784
                                                    beta-lactam antibiotic 772
                                                      cephem 537
                                                        cephalosporin 536
                                                          3-(carbamoyloxymethyl)cephalosporin 7
                                                            cefuroxime 7
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.