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Accession:CHEBI:3534 term browser browse the term
Definition:A semisynthetic first-generation cephalosporin antibiotic having methyl and beta-(2R)-2-amino-2-phenylacetamido groups at the 3- and 7- of the cephem skeleton, respectively. It is effective against both Gram-negative and Gram-positive organisms, and is used for treatment of infections of the skin, respiratory tract and urinary tract.
Synonyms:exact_synonym: 7beta-[(2R)-2-amino-2-phenylacetamido]-3-methyl-3,4-didehydrocepham-4-carboxylic acid
 related_synonym: (6R,7R)-7-{[(2R)-2-amino-2-phenylacetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;   7-(D-alpha-Aminophenylacetamido)desacetoxycephalosporanic acid;   7-beta-(D-alpha-Amino-alpha-phenylacetylamino)-3-methyl-3-cephem-4-carboxylic acid;   CEX;   Cefalexin;   Celexin;   Cepastar;   Cepexin;   Cephacillin;   Ceporexin;   Formula=C16H17N3O4S;   InChI=1S/C16H17N3O4S/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9/h2-6,10-11,15H,7,17H2,1H3,(H,18,20)(H,22,23)/t10-,11-,15-/m1/s1;   InChIKey=ZAIPMKNFIOOWCQ-UEKVPHQBSA-N;   SMILES=[H][C@]12SCC(C)=C(N1C(=O)[C@H]2NC(=O)[C@H](N)c1ccccc1)C(O)=O;   cefalexina;   cefalexine;   cefalexinum
 xref: Beilstein:965503 "Beilstein";   CAS:15686-71-2 "ChemIDplus";   CAS:15686-71-2 "KEGG COMPOUND";   DrugBank:DB00567;   Drug_Central:571 "DrugCentral";   HMDB:HMDB0014707;   KEGG:C06895;   KEGG:D00263;   LINCS:LSM-5957
 xref_mesh: MESH:D002506
 xref: PMID:10930630 "Europe PMC";   PMID:12569987 "Europe PMC";   PMID:12833570 "Europe PMC";   PMID:1384868 "Europe PMC";   PMID:2083978 "Europe PMC";   PMID:22559990 "Europe PMC";   PMID:23061564 "Europe PMC";   PMID:23457080 "Europe PMC";   PMID:23545436 "Europe PMC";   PMID:23688276 "Europe PMC";   PMID:23811740 "Europe PMC";   PMID:24268227 "Europe PMC";   PMID:24548092 "Europe PMC";   PMID:29017833 "Europe PMC";   Patent:US3275626;   Patent:US3507861;   Reaxys:4238892 "Reaxys";   VSDB:1791;   Wikipedia:Cefalexin
 cyclic_relationship: is_conjugate_acid_of CHEBI:59392

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cephalexin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G RT1-Ha RT1 class II, locus Ha JBrowse link 20 3,875,478 3,885,140 RGD:6480464
G Slc15a1 solute carrier family 15 member 1 JBrowse link 15 106,800,081 106,844,668 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19728
    role 19675
      biological role 19673
        antimicrobial agent 17211
          antibacterial agent 12926
            antibacterial drug 3089
              cephalexin 2
                cefalexin pivoxil 0
                cephalexin monohydrate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19728
    subatomic particle 19724
      composite particle 19724
        hadron 19724
          baryon 19724
            nucleon 19724
              atomic nucleus 19724
                atom 19724
                  main group element atom 19610
                    p-block element atom 19610
                      carbon group element atom 19501
                        carbon atom 19494
                          organic molecular entity 19494
                            organic group 18413
                              organic divalent group 18404
                                organodiyl group 18404
                                  carbonyl group 18293
                                    carbonyl compound 18293
                                      carboxylic acid 17960
                                        carboacyl group 17072
                                          univalent carboacyl group 17072
                                            carbamoyl group 16801
                                              carboxamide 16801
                                                lactam 7814
                                                  beta-lactam 784
                                                    beta-lactam antibiotic 772
                                                      cephem 537
                                                        cephalosporin 536
                                                          cephalexin 2
                                                            cefalexin pivoxil 0
                                                            cephalexin monohydrate 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.