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ONTOLOGY REPORT - ANNOTATIONS


Term:1,4-benzodiazepinone
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Accession:CHEBI:35500 term browser browse the term
Synonyms:related_synonym: 1,4-benzodiazepinones


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clobazam term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcc2 ATP binding cassette subfamily C member 2 JBrowse link 1 263,554,426 263,612,556 RGD:6480464
G F2 coagulation factor II JBrowse link 3 80,529,468 80,542,993 RGD:6480464
G Sele selectin E JBrowse link 13 82,355,234 82,365,323 RGD:6480464
G Serpinc1 serpin family C member 1 JBrowse link 13 78,806,107 78,820,375 RGD:6480464
clonazepam term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:6480464
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:6480464
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 JBrowse link 7 99,142,431 99,183,540 RGD:6480464
G Dcx doublecortin JBrowse link X 115,098,675 115,175,515 RGD:6480464
G Ephx1 epoxide hydrolase 1 JBrowse link 13 99,271,390 99,300,580 RGD:6480464
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 JBrowse link 11 65,022,100 65,058,546 RGD:6480464
devazepide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cckar cholecystokinin A receptor JBrowse link 14 59,610,939 59,619,786 RGD:6480464
G Fos Fos proto-oncogene, AP-1 transcription factor subunit JBrowse link 6 109,300,433 109,303,299 RGD:6480464
diazepam term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akr1c1 aldo-keto reductase family 1, member C1 JBrowse link 17 69,441,253 69,460,334 RGD:6480464
G Akr1c2 aldo-keto reductase family 1, member C2 JBrowse link 17 69,388,337 69,435,160 RGD:6480464
G Akr1c3 aldo-keto reductase family 1, member C3 JBrowse link 17 69,761,126 69,778,021 RGD:6480464
G Alb albumin JBrowse link 14 19,176,275 19,191,793 RGD:6480464
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:6480464
G Bdnf brain-derived neurotrophic factor JBrowse link 3 100,768,637 100,819,216 RGD:6480464
G Bgn biglycan JBrowse link X 157,319,042 157,331,204 RGD:6480464
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:6480464
G Ccn3 cellular communication network factor 3 JBrowse link 7 94,375,134 94,382,154 RGD:6480464
G Cnr1 cannabinoid receptor 1 JBrowse link 5 49,307,584 49,333,064 RGD:6480464
G Col1a1 collagen type I alpha 1 chain JBrowse link 10 82,745,801 82,762,790 RGD:6480464
G Col7a1 collagen type VII alpha 1 chain JBrowse link 8 117,694,441 117,726,844 RGD:6480464
G Cort cortistatin JBrowse link 5 165,942,780 165,944,221 RGD:6480464
G Creb1 cAMP responsive element binding protein 1 JBrowse link 9 71,229,753 71,298,994 RGD:6480464
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 JBrowse link 7 99,142,431 99,183,540 RGD:6480464
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 JBrowse link 1 83,103,925 83,119,578 RGD:6480464
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 JBrowse link 1 147,713,879 147,814,410 RGD:6480464
G Fgf2 fibroblast growth factor 2 JBrowse link 2 124,081,072 124,134,133 RGD:6480464
G Fgfr2 fibroblast growth factor receptor 2 JBrowse link 1 200,590,951 200,696,946 RGD:6480464
G Fmod fibromodulin JBrowse link 13 50,874,886 50,885,503 RGD:6480464
G Fos Fos proto-oncogene, AP-1 transcription factor subunit JBrowse link 6 109,300,433 109,303,299 RGD:6480464
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 JBrowse link 20 1,955,344 1,984,907 RGD:6480464
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 JBrowse link 10 27,310,718 27,371,802 RGD:6480464
G Gabra2 gamma-aminobutyric acid type A receptor subunit alpha 2 JBrowse link 14 39,662,411 39,801,082 RGD:6480464
G Gabra3 gamma-aminobutyric acid type A receptor subunit alpha 3 JBrowse link X 152,414,332 152,642,607 RGD:6480464
G Gabra4 gamma-aminobutyric acid type A receptor subunit alpha 4 JBrowse link 14 39,154,072 39,230,994 RGD:6480464
G Gabra5 gamma-aminobutyric acid type A receptor subunit alpha 5 JBrowse link 1 112,833,941 112,947,482 RGD:6480464
G Gabra6 gamma-aminobutyric acid type A receptor subunit alpha6 JBrowse link 10 27,847,447 27,862,896 RGD:6480464
G Gabrb1 gamma-aminobutyric acid type A receptor subunit beta1 JBrowse link 14 38,631,192 39,112,598 RGD:6480464
G Gabrb2 gamma-aminobutyric acid type A receptor subunit beta 2 JBrowse link 10 27,973,694 28,193,072 RGD:6480464
G Gabrb3 gamma-aminobutyric acid type A receptor subunit beta 3 JBrowse link 1 113,034,251 113,265,364 RGD:6480464
G Gabrd gamma-aminobutyric acid type A receptor subunit delta JBrowse link 5 172,797,478 172,809,374 RGD:6480464
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 JBrowse link 10 27,090,913 27,179,786 RGD:6480464
G Gabrq gamma-aminobutyric acid type A receptor subunit theta JBrowse link X 152,852,230 152,869,012 RGD:6480464
G Gad1 glutamate decarboxylase 1 JBrowse link 3 56,861,440 56,902,139 RGD:6480464
G Gad2 glutamate decarboxylase 2 JBrowse link 17 89,171,576 89,234,770 RGD:6480464
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A JBrowse link 10 5,707,806 6,123,568 RGD:6480464
G Hcn1 hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 JBrowse link 2 50,099,576 50,499,799 RGD:6480464
G Itga5 integrin subunit alpha 5 JBrowse link 7 144,970,444 144,993,652 RGD:6480464
G Itga6 integrin subunit alpha 6 JBrowse link 3 58,442,904 58,515,124 RGD:6480464
G Jun Jun proto-oncogene, AP-1 transcription factor subunit JBrowse link 5 114,011,184 114,014,277 RGD:6480464
G Junb JunB proto-oncogene, AP-1 transcription factor subunit JBrowse link 19 26,092,972 26,094,756 RGD:6480464
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6480464
G Mapk14 mitogen activated protein kinase 14 JBrowse link 20 5,933,290 5,995,137 RGD:6480464
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6480464
G Mapk8 mitogen-activated protein kinase 8 JBrowse link 16 9,620,854 9,709,342 RGD:6480464
G Nefh neurofilament heavy JBrowse link 14 85,181,572 85,191,557 RGD:6480464
G Nfkb1 nuclear factor kappa B subunit 1 JBrowse link 2 240,773,520 240,890,053 RGD:6480464
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:6480464
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 JBrowse link 11 65,022,100 65,058,546 RGD:6480464
G Odc1 ornithine decarboxylase 1 JBrowse link 6 42,852,529 42,859,142 RGD:6480464
G Pdyn prodynorphin JBrowse link 3 122,194,327 122,206,671 RGD:6480464
G Penk proenkephalin JBrowse link 5 17,056,412 17,061,762 RGD:6480464
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6480464
G Slc12a5 solute carrier family 12 member 5 JBrowse link 3 161,433,303 161,465,078 RGD:6480464
G Slc1a3 solute carrier family 1 member 3 JBrowse link 2 57,860,881 57,935,363 RGD:6480464
G Slc22a2 solute carrier family 22 member 2 JBrowse link 1 48,318,025 48,360,219 RGD:6480464
G Slc22a6 solute carrier family 22 member 6 JBrowse link 1 224,824,809 224,833,284 RGD:6480464
G Slc2a1 solute carrier family 2 member 1 JBrowse link 5 138,154,677 138,182,897 RGD:6480464
G Slc6a11 solute carrier family 6 member 11 JBrowse link 4 146,106,386 146,223,228 RGD:6480464
G Slc6a12 solute carrier family 6 member 12 JBrowse link 4 153,921,199 153,941,333 RGD:6480464
G Tac1 tachykinin, precursor 1 JBrowse link 4 33,638,853 33,646,819 RGD:6480464
G Tat tyrosine aminotransferase JBrowse link 19 41,675,639 41,686,195 RGD:6480464
G Tgfb3 transforming growth factor, beta 3 JBrowse link 6 109,913,757 109,936,217 RGD:6480464
G Tgfbr1 transforming growth factor, beta receptor 1 JBrowse link 5 63,056,071 63,119,635 RGD:6480464
G Tgfbr2 transforming growth factor, beta receptor 2 JBrowse link 8 124,310,288 124,399,345 RGD:6480464
G Tgfbr3 transforming growth factor beta receptor 3 JBrowse link 14 3,506,416 3,680,508 RGD:6480464
G Tnc tenascin C JBrowse link 5 79,789,686 79,874,555 RGD:6480464
G Trh thyrotropin releasing hormone JBrowse link 4 124,110,716 124,113,242 RGD:6480464
G Trhr thyrotropin releasing hormone receptor JBrowse link 7 83,113,641 83,153,520 RGD:6480464
G Tspo translocator protein JBrowse link 7 124,460,358 124,470,610 RGD:6480464
G Vtn vitronectin JBrowse link 10 65,767,960 65,771,040 RGD:6480464
flunitrazepam term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akr1c1 aldo-keto reductase family 1, member C1 JBrowse link 17 69,441,253 69,460,334 RGD:6480464
G Akr1c2 aldo-keto reductase family 1, member C2 JBrowse link 17 69,388,337 69,435,160 RGD:6480464
G Akr1c3 aldo-keto reductase family 1, member C3 JBrowse link 17 69,761,126 69,778,021 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Casp7 caspase 7 JBrowse link 1 277,190,557 277,242,779 RGD:6480464
G Crp C-reactive protein JBrowse link 13 91,080,448 91,081,358 RGD:6480464
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 JBrowse link 1 147,713,879 147,814,410 RGD:6480464
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 JBrowse link 12 19,074,288 19,114,491 RGD:6480464
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 JBrowse link 10 27,310,718 27,371,802 RGD:6480464
G Gabra2 gamma-aminobutyric acid type A receptor subunit alpha 2 JBrowse link 14 39,662,411 39,801,082 RGD:6480464
G Gabrb3 gamma-aminobutyric acid type A receptor subunit beta 3 JBrowse link 1 113,034,251 113,265,364 RGD:6480464
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 JBrowse link 10 27,090,913 27,179,786 RGD:6480464
G Sstr3 somatostatin receptor 3 JBrowse link 7 119,760,881 119,768,082 RGD:6480464
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 JBrowse link 9 95,295,701 95,302,822 RGD:6480464
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 JBrowse link 9 95,285,592 95,302,822 RGD:6480464
flurazepam term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 JBrowse link 10 27,310,718 27,371,802 RGD:6480464
G Gabrb2 gamma-aminobutyric acid type A receptor subunit beta 2 JBrowse link 10 27,973,694 28,193,072 RGD:6480464
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:6480464
G Trh thyrotropin releasing hormone JBrowse link 4 124,110,716 124,113,242 RGD:6480464
G Trhr thyrotropin releasing hormone receptor JBrowse link 7 83,113,641 83,153,520 RGD:6480464
nimetazepam term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Casp7 caspase 7 JBrowse link 1 277,190,557 277,242,779 RGD:6480464
G Slc22a2 solute carrier family 22 member 2 JBrowse link 1 48,318,025 48,360,219 RGD:6480464
nitrazepam term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akr1c1 aldo-keto reductase family 1, member C1 JBrowse link 17 69,441,253 69,460,334 RGD:6480464
G Akr1c2 aldo-keto reductase family 1, member C2 JBrowse link 17 69,388,337 69,435,160 RGD:6480464
G Akr1c3 aldo-keto reductase family 1, member C3 JBrowse link 17 69,761,126 69,778,021 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Casp7 caspase 7 JBrowse link 1 277,190,557 277,242,779 RGD:6480464
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:6480464
oxazepam term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arf2 ADP-ribosylation factor 2 JBrowse link 10 92,018,562 92,040,335 RGD:6480464
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:6480464
G Ces1d carboxylesterase 1D JBrowse link 19 15,195,514 15,239,827 RGD:6480464
G Cidea cell death-inducing DFFA-like effector a JBrowse link 18 63,082,861 63,108,450 RGD:6480464
G Cish cytokine inducible SH2-containing protein JBrowse link 8 116,054,547 116,059,494 RGD:6480464
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:6480464
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 JBrowse link 7 99,142,431 99,183,540 RGD:6480464
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 JBrowse link 1 83,103,925 83,119,578 RGD:6480464
G Egfr epidermal growth factor receptor JBrowse link 14 99,919,485 100,104,136 RGD:6480464
G Egr1 early growth response 1 JBrowse link 18 27,657,903 27,660,101 RGD:6480464
G Gadd45b growth arrest and DNA-damage-inducible, beta JBrowse link 7 11,646,283 11,648,338 RGD:6480464
G Igfbp1 insulin-like growth factor binding protein 1 JBrowse link 14 87,448,716 87,453,783 RGD:6480464
G Inhba inhibin subunit beta A JBrowse link 17 51,894,869 51,919,998 RGD:6480464
G Junb JunB proto-oncogene, AP-1 transcription factor subunit JBrowse link 19 26,092,972 26,094,756 RGD:6480464
G Lzts2 leucine zipper tumor suppressor 2 JBrowse link 1 264,765,256 264,776,553 RGD:6480464
G Maf MAF bZIP transcription factor JBrowse link 19 48,179,826 48,200,995 RGD:6480464
G Maff MAF bZIP transcription factor F JBrowse link 7 120,580,743 120,592,095 RGD:6480464
G Map3k7 mitogen activated protein kinase kinase kinase 7 JBrowse link 5 47,183,142 47,244,424 RGD:6480464
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:6480464
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 JBrowse link 13 89,585,072 89,591,278 RGD:6480464
G Ppara peroxisome proliferator activated receptor alpha JBrowse link 7 126,618,872 126,687,282 RGD:6480464
G St6gal1 ST6 beta-galactoside alpha-2,6-sialyltransferase 1 JBrowse link 11 80,927,601 80,981,424 RGD:6480464
G Stat5b signal transducer and activator of transcription 5B JBrowse link 10 88,686,207 88,712,313 RGD:6480464
G Tff1 trefoil factor 1 JBrowse link 20 9,892,124 9,895,984 RGD:6480464
G Tnfaip2 TNF alpha induced protein 2 JBrowse link 6 135,890,869 135,903,647 RGD:6480464
G Tsc22d1 TSC22 domain family, member 1 JBrowse link 15 58,554,358 58,658,156 RGD:6480464
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 JBrowse link 9 95,161,157 95,302,822 RGD:6480464
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 JBrowse link 14 22,597,103 22,619,968 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19789
    role 19735
      biological role 19734
        biophysical role 12289
          membrane transport modulator 12069
            GABA modulator 4656
              benzodiazepine 534
                1,4-benzodiazepinone 114
                  2,5-dioxo-2,3,4,5-tetrahydro-1H-1,4-benzodiazepine-3-carboxylic acid 0
                  5-(2-chlorophenyl)-7-(dihydroxyamino)-1,3-dihydro-1,4-benzodiazepin-2-one 0
                  Ro 5-3335 0
                  cinolazepam 0
                  clobazam 4
                  clonazepam 6
                  clorazepic acid 0
                  compound E 0
                  cyclopeptine + 0
                  dehydrocyclopeptine + 0
                  devazepide 2
                  diazepam + 72
                  didesethylflurazepam 0
                  fludiazepam 0
                  flunitrazepam 15
                  flurazepam + 5
                  hydroxyethylflurazepam 0
                  lormetazepam 0
                  nimetazepam 3
                  nitrazepam + 7
                  nordazepam 0
                  oxazepam 28
Path 2
Term Annotations click to browse term
  CHEBI ontology 19789
    subatomic particle 19787
      composite particle 19787
        hadron 19787
          baryon 19787
            nucleon 19787
              atomic nucleus 19787
                atom 19787
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19569
                        carbon atom 19558
                          organic molecular entity 19558
                            organic molecule 19480
                              organic cyclic compound 19239
                                organic heterocyclic compound 18352
                                  organonitrogen heterocyclic compound 17218
                                    benzodiazepine 534
                                      1,4-benzodiazepinone 114
                                        2,5-dioxo-2,3,4,5-tetrahydro-1H-1,4-benzodiazepine-3-carboxylic acid 0
                                        5-(2-chlorophenyl)-7-(dihydroxyamino)-1,3-dihydro-1,4-benzodiazepin-2-one 0
                                        Ro 5-3335 0
                                        cinolazepam 0
                                        clobazam 4
                                        clonazepam 6
                                        clorazepic acid 0
                                        compound E 0
                                        cyclopeptine + 0
                                        dehydrocyclopeptine + 0
                                        devazepide 2
                                        diazepam + 72
                                        didesethylflurazepam 0
                                        fludiazepam 0
                                        flunitrazepam 15
                                        flurazepam + 5
                                        hydroxyethylflurazepam 0
                                        lormetazepam 0
                                        nimetazepam 3
                                        nitrazepam + 7
                                        nordazepam 0
                                        oxazepam 28
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.