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ONTOLOGY REPORT - ANNOTATIONS


Term:icosa-6,8,10,14-tetraenoic acid
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Accession:CHEBI:36045 term browser browse the term
Definition:Any icosatetraenoic acid with the double bonds at positions 6, 8, 10 and 14.
Synonyms:related_synonym: 6,8,10,14-18:4;   6,8,10,14-eicosatetraenoic acid;   6,8,10,14-eicosatetraenoic acids;   6,8,10,14-icosatetraenoic acid;   6,8,10,14-icosatetraenoic acids;   C18:4, n-6,10,12,14;   Formula=C20H32O2;   InChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,10-15H,2-5,8-9,16-19H2,1H3,(H,21,22);   InChIKey=RUDAIQLQFUMSCE-UHFFFAOYSA-N;   SMILES=[H]C(CCC=C([H])C=C([H])C=C([H])CCCCC(O)=O)=CCCCCC;   eicosa-6,8,10,14-tetraenoic acid;   eicosa-6,8,10,14-tetraenoic acids;   icosa-6,8,10,14-tetraenoic acids


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leukotriene B4 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acta2 actin alpha 2, smooth muscle JBrowse link 1 252,537,614 252,550,394 RGD:6480464
G Ahr aryl hydrocarbon receptor JBrowse link 6 54,963,990 55,001,806 RGD:6480464
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:6480464
G Alox5 arachidonate 5-lipoxygenase JBrowse link 4 148,398,004 148,446,308 RGD:6480464
G Alox5ap arachidonate 5-lipoxygenase activating protein JBrowse link 12 6,854,930 6,879,112 RGD:6480464
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:6480464
G C5 complement C5 JBrowse link 3
3
14,049,993
14,206,466
14,113,931
14,229,141
RGD:6480464
G Ccl12 chemokine (C-C motif) ligand 12 JBrowse link 10 69,476,866 69,478,416 RGD:6480464
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:6480464
G Ccl5 C-C motif chemokine ligand 5 JBrowse link 10 70,739,764 70,744,303 RGD:6480464
G Col1a1 collagen type I alpha 1 chain JBrowse link 10 82,745,801 82,762,790 RGD:6480464
G Csf2 colony stimulating factor 2 JBrowse link 10 39,602,089 39,604,070 RGD:6480464
G Cxcl3 C-X-C motif chemokine ligand 3 JBrowse link 14 18,820,168 18,839,659 RGD:6480464
G Cysltr1 cysteinyl leukotriene receptor 1 JBrowse link X 77,671,028 77,700,491 RGD:6480464
G Fgf2 fibroblast growth factor 2 JBrowse link 2 124,081,072 124,134,133 RGD:6480464
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:6480464
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 JBrowse link 19 37,476,083 37,481,326 RGD:6480464
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:6480464
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:6480464
G Il12b interleukin 12B JBrowse link 10 30,034,447 30,048,774 RGD:6480464
G Il13 interleukin 13 JBrowse link 10 38,982,909 38,985,466 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:6480464
G Itgam integrin subunit alpha M JBrowse link 1 199,495,312 199,545,738 RGD:6480464
G Itgb2 integrin subunit beta 2 JBrowse link 20 11,777,773 11,815,647 RGD:6480464
G Lta4h leukotriene A4 hydrolase JBrowse link 7 34,288,333 34,320,243 RGD:6480464
G Ltb4r leukotriene B4 receptor JBrowse link 15 34,449,299 34,453,352 RGD:6480464
G Ltb4r2 leukotriene B4 receptor 2 JBrowse link 15 34,446,478 34,448,220 RGD:6480464
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6480464
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6480464
G Mcl1 MCL1 apoptosis regulator, BCL2 family member JBrowse link 2 197,786,212 197,788,992 RGD:6480464
G Mgst1 microsomal glutathione S-transferase 1 JBrowse link 4 172,119,382 172,134,609 RGD:6480464
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:6480464
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming JBrowse link 1 214,725,482 214,756,653 RGD:6480464
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:6480464
G Pla2g4a phospholipase A2 group IVA JBrowse link 13 67,062,252 67,206,688 RGD:6480464
G Ppara peroxisome proliferator activated receptor alpha JBrowse link 7 126,618,872 126,687,282 RGD:6480464
G Sell selectin L JBrowse link 13 82,369,820 82,387,774 RGD:6480464
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19779
    chemical entity 19778
      atom 19777
        nonmetal atom 19651
          carbon atom 19548
            organic molecular entity 19548
              olefinic compound 14480
                olefinic fatty acid 604
                  icosatetraenoic acid 313
                    icosa-6,8,10,14-tetraenoic acid 39
                      12-dehydro-leukotriene B4 0
                      12-epi-leukotriene B4 0
                      12-oxo-6-trans-leukotriene B4 0
                      20-oxoleukotriene B4 0
                      6-trans-leukotriene B4 + 0
                      Delta(6)-trans,Delta(8)-cis-leukotriene B4 0
                      Delta(6)-trans-12-epi-leukotriene B4 0
                      leukotriene B4 + 39
Path 2
Term Annotations click to browse term
  CHEBI ontology 19779
    subatomic particle 19777
      composite particle 19777
        hadron 19777
          baryon 19777
            nucleon 19777
              atomic nucleus 19777
                atom 19777
                  main group element atom 19664
                    p-block element atom 19664
                      carbon group element atom 19559
                        carbon atom 19548
                          organic molecular entity 19548
                            organic group 18463
                              organic divalent group 18456
                                organodiyl group 18456
                                  carbonyl group 18356
                                    carbonyl compound 18356
                                      carboxylic acid 18027
                                        monocarboxylic acid 17287
                                          fatty acid 15828
                                            unsaturated fatty acid 909
                                              polyunsaturated fatty acid 662
                                                fatty acid 20:4 313
                                                  icosatetraenoic acid 313
                                                    icosa-6,8,10,14-tetraenoic acid 39
                                                      12-dehydro-leukotriene B4 0
                                                      12-epi-leukotriene B4 0
                                                      12-oxo-6-trans-leukotriene B4 0
                                                      20-oxoleukotriene B4 0
                                                      6-trans-leukotriene B4 + 0
                                                      Delta(6)-trans,Delta(8)-cis-leukotriene B4 0
                                                      Delta(6)-trans-12-epi-leukotriene B4 0
                                                      leukotriene B4 + 39
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.