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ONTOLOGY REPORT - ANNOTATIONS


Term:3-hydroxyisovaleric acid
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Accession:CHEBI:37084 term browser browse the term
Definition:A 3-hydroxy monocarboxylic acid that is isovaleric acid substituted at position 3 by a hydroxy group. Used as indicator of biotin deficiency.
Synonyms:related_synonym: 3-Hydroxy-3-methylbutanoic acid;   3-OH-isovaleric acid;   3-hydroxy-3-methylbutyric acid;   3-hydroxy-isovaleric acid;   3-methyl-3-hydroxybutyric acid;   Formula=C5H10O3;   HMB;   Hmb-d6;   InChI=1S/C5H10O3/c1-5(2,8)3-4(6)7/h8H,3H2,1-2H3,(H,6,7);   InChIKey=AXFYFNCPONWUHW-UHFFFAOYSA-N;   SMILES=CC(C)(O)CC(O)=O;   beta-Hydroxyisovaleric acid;   beta-hydroxy-beta-methylbutyric acid
 xref: Beilstein:1743952 "Beilstein";   CAS:625-08-1 "ChemIDplus";   HMDB:HMDB0000754;   LIPID_MAPS_instance:LMFA01050396 "LIPID MAPS"
 xref_mesh: MESH:C004961
 xref: PMID:12399279 "Europe PMC";   PMID:22770225 "Europe PMC";   PMID:9523856 "Europe PMC";   Reaxys:1743952 "Reaxys";   Wikipedia:Beta-Hydroxy_beta-methylbutyric_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:82957


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3-hydroxyisovaleric acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:6480464
G Fbxo32 F-box protein 32 JBrowse link 7 98,065,664 98,098,071 RGD:6480464
G Usp16 ubiquitin specific peptidase 16 JBrowse link 11 27,101,213 27,130,345 RGD:6480464
G Usp2 ubiquitin specific peptidase 2 JBrowse link 8 48,403,985 48,432,525 RGD:6480464
G Usp28 ubiquitin specific peptidase 28 JBrowse link 8 53,295,188 53,355,572 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19716
    role 19663
      biological role 19661
        biochemical role 19179
          metabolite 19151
            eukaryotic metabolite 18770
              plant metabolite 17103
                isovaleric acid 86
                  3-hydroxyisovaleric acid 5
                    3-hydroxyisovaleryl-CoA 0
                    3-hydroxyisovalerylcarnitine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19716
    subatomic particle 19712
      composite particle 19712
        hadron 19712
          baryon 19712
            nucleon 19712
              atomic nucleus 19712
                atom 19712
                  main group element atom 19598
                    p-block element atom 19598
                      carbon group element atom 19486
                        carbon atom 19480
                          organic molecular entity 19480
                            organic group 18407
                              organic divalent group 18397
                                organodiyl group 18397
                                  carbonyl group 18285
                                    carbonyl compound 18285
                                      carboxylic acid 17940
                                        monocarboxylic acid 17260
                                          fatty acid 15814
                                            short-chain fatty acid 15510
                                              fatty acid 4:0 7007
                                                butyric acid 5281
                                                  methylbutyric acid 972
                                                    isovaleric acid 86
                                                      3-hydroxyisovaleric acid 5
                                                        3-hydroxyisovaleryl-CoA 0
                                                        3-hydroxyisovalerylcarnitine 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.