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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:protein kinase inhibitor
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Accession:CHEBI:37699 term browser browse the term
Definition:An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of protein kinases.
Synonyms:related_synonym: protein kinase inhibitors
 alt_id: MESH:D047428
 xref_mesh: MESH:D047428


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Term Annotations click to browse term
  CHEBI ontology 19785
    role 19732
      biological role 19732
        biochemical role 19281
          enzyme inhibitor 18148
            EC 2.* (transferase) inhibitor 13808
              EC 2.7.* (P-containing group transferase) inhibitor 13493
                protein kinase inhibitor 13023
                  (+)-makassaric acid 0
                  (+)-subersic acid 0
                  1,4-diamino-2,3-dicyano-1,4-bis(phenylthio)butadiene 0
                  1,8-dihydroxy-4-nitroxanthen-9-one 0
                  2-(\{2-[(3-hydroxyphenyl)amino]pyrimidin-4-yl\}amino)benzamide 0
                  Aurora kinase inhibitor + 4000
                  CMB4563 0
                  CZC8004 0
                  DMH1 0
                  EC 2.7.10.* (protein-tyrosine kinase) inhibitor + 9364
                  EC 2.7.11.* (protein-serine/threonine kinase) inhibitor + 8161
                  EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor + 682
                  Ro 320-1195 + 0
                  XMD8-92 0
                  aminopurvalanol 0
                  epidermal growth factor receptor antagonist + 308
                  erlotinib + 127
                  erlotinib hydrochloride 127
                  gamma-mangostin 6
                  mTOR inhibitor + 485
                  miltefosine 2
                  pelitinib + 0
                  piceatannol + 0
                  purvalanol B 0
                  quercetin + 3999
                  salt-inducible kinase 2 inhibitor + 0
                  sangivamycin 0
                  tyrosine kinase inhibitor + 11378
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