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ONTOLOGY REPORT - ANNOTATIONS


Term:pyridone
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Accession:CHEBI:38183 term browser browse the term
Synonyms:related_synonym: pyridones


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3,5,6-trichloropyridine-2-one term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ACHE acetylcholinesterase (Cartwright blood group) JBrowse link 7 100,889,994 100,896,994 RGD:6480464
G AFP alpha fetoprotein JBrowse link 4 73,436,221 73,456,174 RGD:6480464
G BCHE butyrylcholinesterase JBrowse link 3 165,772,904 165,837,423 RGD:6480464
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 JBrowse link 10 94,762,681 94,855,547 RGD:6480464
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 JBrowse link 7 99,756,967 99,784,184 RGD:6480464
G KDR kinase insert domain receptor JBrowse link 4 55,078,481 55,125,595 RGD:6480464
G MYH6 myosin heavy chain 6 JBrowse link 14 23,381,987 23,408,273 RGD:6480464
G NANOG Nanog homeobox JBrowse link 12 7,789,402 7,799,146 RGD:6480464
G NEFM neurofilament medium JBrowse link 8 24,913,761 24,919,093 RGD:6480464
G NES nestin JBrowse link 1 156,668,763 156,677,407 RGD:6480464
G PNPLA6 patatin like phospholipase domain containing 6 JBrowse link 19 7,534,164 7,561,767 RGD:6480464
G POU5F1 POU class 5 homeobox 1 JBrowse link 6 31,164,337 31,170,682 RGD:6480464
CGP 28014 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G COMT catechol-O-methyltransferase JBrowse link 22 19,941,772 19,969,975 RGD:6480464
ciclopirox term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AR androgen receptor JBrowse link X 67,544,021 67,730,619 RGD:6480464
G BIRC5 baculoviral IAP repeat containing 5 JBrowse link 17 78,214,253 78,225,635 RGD:6480464
G ESR1 estrogen receptor 1 JBrowse link 6 151,654,148 152,129,619 RGD:6480464
G FKBP5 FKBP prolyl isomerase 5 JBrowse link 6 35,573,585 35,728,583 RGD:6480464
G FLT4 fms related receptor tyrosine kinase 4 JBrowse link 5 180,601,506 180,650,298 RGD:6480464
G HIF1A hypoxia inducible factor 1 subunit alpha JBrowse link 14 61,695,513 61,748,259 RGD:6480464
G HMOX1 heme oxygenase 1 JBrowse link 22 35,381,096 35,394,207 RGD:6480464
G KCNH2 potassium voltage-gated channel subfamily H member 2 JBrowse link 7 150,944,956 150,978,321 RGD:6480464
G MAPK1 mitogen-activated protein kinase 1 JBrowse link 22 21,759,657 21,867,680 RGD:6480464
G MAPK3 mitogen-activated protein kinase 3 JBrowse link 16 30,114,105 30,123,309 RGD:6480464
G MAPT microtubule associated protein tau JBrowse link 17 45,894,382 46,028,334 RGD:6480464
G NR3C1 nuclear receptor subfamily 3 group C member 1 JBrowse link 5 143,277,931 143,435,512 RGD:6480464
G PGR progesterone receptor JBrowse link 11 101,029,624 101,130,681 RGD:6480464
G RRM2 ribonucleotide reductase regulatory subunit M2 JBrowse link 2 10,122,568 10,211,010 RGD:6480464
deferiprone term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AKT1 AKT serine/threonine kinase 1 JBrowse link 14 104,769,349 104,795,748 RGD:6480464
G CCL2 C-C motif chemokine ligand 2 JBrowse link 17 34,255,285 34,257,203 RGD:6480464
G CHUK component of inhibitor of nuclear factor kappa B kinase complex JBrowse link 10 100,188,298 100,229,610 RGD:6480464
G FXN frataxin JBrowse link 9 69,035,752 69,079,076 RGD:6480464
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta JBrowse link 8 42,270,727 42,332,653 RGD:6480464
G MAPK1 mitogen-activated protein kinase 1 JBrowse link 22 21,759,657 21,867,680 RGD:6480464
G MAPK3 mitogen-activated protein kinase 3 JBrowse link 16 30,114,105 30,123,309 RGD:6480464
G SOD1 superoxide dismutase 1 JBrowse link 21 31,659,693 31,668,931 RGD:6480464
G TF transferrin JBrowse link 3 133,661,998 133,796,641 RGD:6480464
G TNF tumor necrosis factor JBrowse link 6 31,575,565 31,578,336 RGD:6480464
huperzine A term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABCB1 ATP binding cassette subfamily B member 1 JBrowse link 7 87,503,017 87,713,323 RGD:6480464
G ACHE acetylcholinesterase (Cartwright blood group) JBrowse link 7 100,889,994 100,896,994 RGD:6480464
G ALB albumin JBrowse link 4 73,404,287 73,421,482 RGD:6480464
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 JBrowse link 15 74,748,845 74,756,607 RGD:6480464
G IL1B interleukin 1 beta JBrowse link 2 112,829,751 112,836,843 RGD:6480464
G RELA RELA proto-oncogene, NF-kB subunit JBrowse link 11 65,653,596 65,662,972 RGD:6480464
G TNF tumor necrosis factor JBrowse link 6 31,575,565 31,578,336 RGD:6480464
L-mimosine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ARNT aryl hydrocarbon receptor nuclear translocator JBrowse link 1 150,809,713 150,876,737 RGD:6480464
G ATF1 activating transcription factor 1 JBrowse link 12 50,763,682 50,821,162 RGD:6480464
G BCL2 BCL2 apoptosis regulator JBrowse link 18 63,123,346 63,320,280 RGD:6480464
G CASP3 caspase 3 JBrowse link 4 184,627,696 184,649,475 RGD:6480464
G CASP9 caspase 9 JBrowse link 1 15,491,401 15,524,912 RGD:6480464
G CAT catalase JBrowse link 11 34,438,934 34,472,060 RGD:6480464
G CCND1 cyclin D1 JBrowse link 11 69,641,156 69,654,474 RGD:6480464
G CDKN1A cyclin dependent kinase inhibitor 1A JBrowse link 6 36,676,463 36,687,332 RGD:6480464
G CDKN1B cyclin dependent kinase inhibitor 1B JBrowse link 12 12,717,368 12,722,369 RGD:6480464
G CREB1 cAMP responsive element binding protein 1 JBrowse link 2 207,529,943 207,605,988 RGD:6480464
G ECE1 endothelin converting enzyme 1 JBrowse link 1 21,217,250 21,345,504 RGD:6480464
G EDN1 endothelin 1 JBrowse link 6 12,256,463 12,297,194 RGD:6480464
G HIF1A hypoxia inducible factor 1 subunit alpha JBrowse link 14 61,695,513 61,748,259 RGD:6480464
G LHCGR luteinizing hormone/choriogonadotropin receptor JBrowse link 2 48,686,774 48,755,724 RGD:6480464
G NMBR neuromedin B receptor JBrowse link 6 142,074,484 142,147,122 RGD:6480464
G SLC2A1 solute carrier family 2 member 1 JBrowse link 1 42,925,353 42,958,868 RGD:6480464
G STAT3 signal transducer and activator of transcription 3 JBrowse link 17 42,313,324 42,388,502 RGD:6480464
G TNF tumor necrosis factor JBrowse link 6 31,575,565 31,578,336 RGD:6480464
G TNFRSF1A TNF receptor superfamily member 1A JBrowse link 12 6,328,771 6,342,076 RGD:6480464
milrinone term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide JBrowse link 4 99,336,497 99,352,746 RGD:6480464
G AKIP1 A-kinase interacting protein 1 JBrowse link 11 8,911,117 8,920,079 RGD:6480464
G ANGPTL4 angiopoietin like 4 JBrowse link 19 8,364,129 8,374,373 RGD:6480464
G AQP7 aquaporin 7 JBrowse link 9 33,383,135 33,402,682 RGD:6480464
G ARNTL aryl hydrocarbon receptor nuclear translocator like JBrowse link 11 13,276,552 13,387,268 RGD:6480464
G ASPN asporin JBrowse link 9 92,456,205 92,482,506 RGD:6480464
G CFTR CF transmembrane conductance regulator JBrowse link 7 117,480,025 117,668,665 RGD:6480464
G CHTF8 chromosome transmission fidelity factor 8 JBrowse link 16 69,118,010 69,132,588 RGD:6480464
G CREM cAMP responsive element modulator JBrowse link 10 35,126,830 35,212,958 RGD:6480464
G CRP C-reactive protein JBrowse link 1 159,712,289 159,714,589 RGD:6480464
G CSRP2 cysteine and glycine rich protein 2 JBrowse link 12 76,858,709 76,879,019 RGD:6480464
G CTHRC1 collagen triple helix repeat containing 1 JBrowse link 8 103,371,538 103,382,989 RGD:6480464
G CXCL8 C-X-C motif chemokine ligand 8 JBrowse link 4 73,740,569 73,743,716 RGD:6480464
G DBP D-box binding PAR bZIP transcription factor JBrowse link 19 48,630,030 48,637,379 RGD:6480464
G EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 JBrowse link 10 70,404,145 70,428,618 RGD:6480464
G FAM171A1 family with sequence similarity 171 member A1 JBrowse link 10 15,211,643 15,374,532 RGD:6480464
G FHL1 four and a half LIM domains 1 JBrowse link X 136,146,702 136,211,359 RGD:6480464
G GADD45G growth arrest and DNA damage inducible gamma JBrowse link 9 89,605,009 89,606,555 RGD:6480464
G GPNMB glycoprotein nmb JBrowse link 7 23,246,766 23,275,110 RGD:6480464
G HADH hydroxyacyl-CoA dehydrogenase JBrowse link 4 107,989,839 108,035,175 RGD:6480464
G IGKC immunoglobulin kappa constant JBrowse link 2 88,857,361 88,857,683 RGD:6480464
G IL6 interleukin 6 JBrowse link 7 22,725,889 22,732,002 RGD:6480464
G LYZ lysozyme JBrowse link 12 69,348,381 69,354,234 RGD:6480464
G MSI2 musashi RNA binding protein 2 JBrowse link 17 57,255,851 57,684,689 RGD:6480464
G MYH7 myosin heavy chain 7 JBrowse link 14 23,412,740 23,435,677 RGD:6480464
G MYL1 myosin light chain 1 JBrowse link 2 210,290,150 210,315,174 RGD:6480464
G NOCT nocturnin JBrowse link 4 139,015,781 139,045,939 RGD:6480464
G NOS1 nitric oxide synthase 1 JBrowse link 12 117,208,142 117,361,802 RGD:6480464
G NPPA natriuretic peptide A JBrowse link 1 11,845,709 11,847,783 RGD:6480464
G NR4A3 nuclear receptor subfamily 4 group A member 3 JBrowse link 9 99,821,855 99,866,893 RGD:6480464
G PER2 period circadian regulator 2 JBrowse link 2 238,244,038 238,290,102 RGD:6480464
G POSTN periostin JBrowse link 13 37,562,582 37,598,844 RGD:6480464
G REG3A regenerating family member 3 alpha JBrowse link 2 79,157,006 79,159,753 RGD:6480464
G REN renin JBrowse link 1 204,154,819 204,166,337 RGD:6480464
G S100A4 S100 calcium binding protein A4 JBrowse link 1 153,543,621 153,545,806 RGD:6480464
G SPP1 secreted phosphoprotein 1 JBrowse link 4 87,975,650 87,983,411 RGD:6480464
G THBS4 thrombospondin 4 JBrowse link 5 79,991,296 80,083,753 RGD:6480464
G TIMP1 TIMP metallopeptidase inhibitor 1 JBrowse link X 47,582,408 47,586,789 RGD:6480464
G TNF tumor necrosis factor JBrowse link 6 31,575,565 31,578,336 RGD:6480464
N-methyl-6-pyridone-3-carboxamide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LEPR leptin receptor JBrowse link 1 65,420,652 65,641,559 RGD:6480464
pirfenidone term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ACE angiotensin I converting enzyme JBrowse link 17 63,477,061 63,498,373 RGD:6480464
G ACE2 angiotensin I converting enzyme 2 JBrowse link X 15,494,520 15,602,158 RGD:6480464
G ACTA2 actin alpha 2, smooth muscle JBrowse link 10 88,935,074 88,991,397 RGD:6480464
G AGTR1 angiotensin II receptor type 1 JBrowse link 3 148,697,871 148,743,003 RGD:6480464
G BIRC5 baculoviral IAP repeat containing 5 JBrowse link 17 78,214,253 78,225,635 RGD:6480464
G CAT catalase JBrowse link 11 34,438,934 34,472,060 RGD:6480464
G COL1A1 collagen type I alpha 1 chain JBrowse link 17 50,184,096 50,201,649 RGD:6480464
G COL4A1 collagen type IV alpha 1 chain JBrowse link 13 110,148,963 110,307,157 RGD:6480464
G EGFR epidermal growth factor receptor JBrowse link 7 55,019,017 55,211,628 RGD:6480464
G ESR1 estrogen receptor 1 JBrowse link 6 151,654,148 152,129,619 RGD:6480464
G GPX1 glutathione peroxidase 1 JBrowse link 3 49,357,171 49,358,600 RGD:6480464
G HDAC9 histone deacetylase 9 JBrowse link 7 18,086,825 19,002,416 RGD:6480464
G JUN Jun proto-oncogene, AP-1 transcription factor subunit JBrowse link 1 58,780,791 58,784,047 RGD:6480464
G MAPK12 mitogen-activated protein kinase 12 JBrowse link 22 50,252,901 50,261,810 RGD:6480464
G MAPK14 mitogen-activated protein kinase 14 JBrowse link 6 36,027,677 36,122,964 RGD:6480464
G MMP2 matrix metallopeptidase 2 JBrowse link 16 55,478,830 55,506,691 RGD:6480464
G NOS2 nitric oxide synthase 2 JBrowse link 17 27,756,766 27,800,529 RGD:6480464
G NOX1 NADPH oxidase 1 JBrowse link X 100,843,324 100,874,359 RGD:6480464
G NOX4 NADPH oxidase 4 JBrowse link 11 89,324,353 89,589,557 RGD:6480464
G NR1H3 nuclear receptor subfamily 1 group H member 3 JBrowse link 11 47,248,300 47,269,033 RGD:6480464
G PTPN3 protein tyrosine phosphatase non-receptor type 3 JBrowse link 9 109,375,694 109,538,395 RGD:6480464
G SERPINE1 serpin family E member 1 JBrowse link 7 101,127,104 101,139,247 RGD:6480464
G SMAD7 SMAD family member 7 JBrowse link 18 48,919,853 48,950,711 RGD:6480464
G TGFB1 transforming growth factor beta 1 JBrowse link 19 41,330,323 41,353,922 RGD:6480464
G TIMP1 TIMP metallopeptidase inhibitor 1 JBrowse link X 47,582,408 47,586,789 RGD:6480464
G TNF tumor necrosis factor JBrowse link 6 31,575,565 31,578,336 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 23810
    chemical entity 23773
      atom 23761
        nonmetal atom 23410
          nitrogen atom 20400
            nitrogen molecular entity 20400
              organonitrogen compound 20107
                organonitrogen heterocyclic compound 18611
                  pyridines 8910
                    pyridone 117
                      1-[1-[(2-chloro-6-fluorophenyl)methyl]-2-oxo-3-pyridinyl]-3-(phenylmethyl)urea 0
                      1-[1-[(4-fluorophenyl)methyl]-5-methyl-2-oxo-3-pyridinyl]-3-(phenylmethyl)urea 0
                      3,5,6-trichloropyridine-2-one 12
                      3,6-dichloropyridine-2,5-dione 0
                      3,6-dihydroxypyridine-2,5-dione 0
                      3-cyano-4-phenyl-6-(3-bromo-6-hydroxyphenyl)-2-pyridone 0
                      4-(3,5-dimethylphenoxy)-5-\{[(furan-2-ylmethyl)sulfanyl]methyl\}-3-iodo-6-methylpyridin-2(1H)-one 0
                      4-methoxy-1-methyl-2-oxo-1,2-dihydropyridine-3-carboxylic acid 0
                      4-pyridones + 28
                      5-(2'-carboxyethyl)-4,6-dihydroxypicolinic acid 0
                      5-(3'-carboxy-3'-oxopropenyl)-4,6-dihydroxypicolinic acid 0
                      5-(3'-carboxy-3'-oxopropyl)-4,6-dihydroxypicolinic acid 0
                      6-chloro-3-hydroxypyridine-2,5-dione 0
                      CGP 28014 1
                      LLP-3 0
                      N-(2,6-dichlorobenzoyl)-4-[1,6-dimethyl-2-oxo-4-(trifluoromethyl)-1,2-dihydropyridin-3-yl]-L-phenylalanine 0
                      N-methyl-6-pyridone-3-carboxamide + 1
                      PH 797804 0
                      SPF-32629A 0
                      SPF-32629B 0
                      acromelic acid A 0
                      aspyridone A 0
                      aspyridone B 0
                      chrysogedone A 0
                      chrysogedone B 0
                      ciclopirox + 14
                      emarginatine B 0
                      emarginatine F 0
                      eribaxaban 0
                      huperzine A 7
                      hydroxypyridone antifungal drug + 14
                      ilicicolin H 0
                      indigoidine 0
                      militarinone A 0
                      milrinone 39
                      perampanel + 0
                      pirfenidone 26
                      piroctone + 0
                      pyridoxatin 0
                      ricinine 0
                      streptokordin 0
                      tert-butyl N-\{1-[(1S)-1-\{[(1R,2S)-1-(benzylcarbamoyl)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl]carbamoyl\}-2-cyclopropylethyl]-2-oxopyridin-3-yl\}carbamate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 23810
    subatomic particle 23761
      composite particle 23761
        hadron 23761
          baryon 23761
            nucleon 23761
              atomic nucleus 23761
                atom 23761
                  main group element atom 23578
                    p-block element atom 23578
                      carbon group element atom 23291
                        carbon atom 23245
                          organic molecular entity 23245
                            organic molecule 23109
                              organic cyclic compound 22096
                                organic heterocyclic compound 20740
                                  organic heteromonocyclic compound 17274
                                    pyridines 8910
                                      pyridone 117
                                        1-[1-[(2-chloro-6-fluorophenyl)methyl]-2-oxo-3-pyridinyl]-3-(phenylmethyl)urea 0
                                        1-[1-[(4-fluorophenyl)methyl]-5-methyl-2-oxo-3-pyridinyl]-3-(phenylmethyl)urea 0
                                        3,5,6-trichloropyridine-2-one 12
                                        3,6-dichloropyridine-2,5-dione 0
                                        3,6-dihydroxypyridine-2,5-dione 0
                                        3-cyano-4-phenyl-6-(3-bromo-6-hydroxyphenyl)-2-pyridone 0
                                        4-(3,5-dimethylphenoxy)-5-\{[(furan-2-ylmethyl)sulfanyl]methyl\}-3-iodo-6-methylpyridin-2(1H)-one 0
                                        4-methoxy-1-methyl-2-oxo-1,2-dihydropyridine-3-carboxylic acid 0
                                        4-pyridones + 28
                                        5-(2'-carboxyethyl)-4,6-dihydroxypicolinic acid 0
                                        5-(3'-carboxy-3'-oxopropenyl)-4,6-dihydroxypicolinic acid 0
                                        5-(3'-carboxy-3'-oxopropyl)-4,6-dihydroxypicolinic acid 0
                                        6-chloro-3-hydroxypyridine-2,5-dione 0
                                        CGP 28014 1
                                        LLP-3 0
                                        N-(2,6-dichlorobenzoyl)-4-[1,6-dimethyl-2-oxo-4-(trifluoromethyl)-1,2-dihydropyridin-3-yl]-L-phenylalanine 0
                                        N-methyl-6-pyridone-3-carboxamide + 1
                                        PH 797804 0
                                        SPF-32629A 0
                                        SPF-32629B 0
                                        acromelic acid A 0
                                        aspyridone A 0
                                        aspyridone B 0
                                        chrysogedone A 0
                                        chrysogedone B 0
                                        ciclopirox + 14
                                        emarginatine B 0
                                        emarginatine F 0
                                        eribaxaban 0
                                        huperzine A 7
                                        hydroxypyridone antifungal drug + 14
                                        ilicicolin H 0
                                        indigoidine 0
                                        militarinone A 0
                                        milrinone 39
                                        perampanel + 0
                                        pirfenidone 26
                                        piroctone + 0
                                        pyridoxatin 0
                                        ricinine 0
                                        streptokordin 0
                                        tert-butyl N-\{1-[(1S)-1-\{[(1R,2S)-1-(benzylcarbamoyl)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl]carbamoyl\}-2-cyclopropylethyl]-2-oxopyridin-3-yl\}carbamate 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.