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ONTOLOGY REPORT - ANNOTATIONS


Term:(2E,4E)-hexa-2,4-dienoic acid
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Accession:CHEBI:38358 term browser browse the term
Definition:A sorbic acid having trans-double bonds at positions 2 and 4; a food preservative that can induce cutaneous vasodilation and stinging upon topical application to humans. It is the most thermodynamically stable of the four possible geometric isomers possible, as well as the one with the highest antimicrobial activity.
Synonyms:related_synonym: (2E,4E)-2,4-hexadienoic acid;   (E,E)-1,3-pentadiene-1-carboxylic acid;   (E,E)-2,4-hexadienoic acid;   (E,E)-SA;   (E,E)-sorbic acid;   1,3-pentadiene-1-carboxylic acid;   Formula=C6H8O2;   InChI=1S/C6H8O2/c1-2-3-4-5-6(7)8/h2-5H,1H3,(H,7,8)/b3-2+,5-4+;   InChIKey=WSWCOQWTEOXDQX-MQQKCMAXSA-N;   SA;   SMILES=C\\C=C\\C=C\\C(O)=O;   alpha-trans-gamma-trans-sorbic acid;   trans,trans-2,4-hexadienoic acid;   trans,trans-SA;   trans,trans-sorbic acid
 xref: Beilstein:1098547 "Beilstein";   CAS:110-44-1 "ChemIDplus";   CAS:110-44-1 "NIST Chemistry WebBook";   Gmelin:260824 "Gmelin";   Gmelin:3063 "Gmelin";   LIPID_MAPS_instance:LMFA01030100 "LIPID MAPS"
 xref_mesh: MESH:D013011
 xref: PMID:11206806 "Europe PMC";   PMID:7979442 "Europe PMC"
 cyclic_relationship: is_conjugate_acid_of CHEBI:77869


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(2E,4E)-hexa-2,4-dienoic acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fosl1 FOS like 1, AP-1 transcription factor subunit JBrowse link 1 220,826,560 220,835,066 RGD:6480464
G Orm1 orosomucoid 1 JBrowse link 5 79,179,668 79,182,820 RGD:6480464
G Phex phosphate regulating endopeptidase homolog, X-linked JBrowse link X 40,460,047 40,717,982 RGD:6480464
G Rad51ap1 RAD51 associated protein 1 JBrowse link 4 159,469,803 159,482,869 RGD:6480464
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19754
    chemical entity 19753
      atom 19752
        nonmetal atom 19624
          carbon atom 19517
            organic molecular entity 19517
              lipid 16974
                fatty acid 15829
                  medium-chain fatty acid 2806
                    sorbic acid 5
                      (2E,4E)-hexa-2,4-dienoic acid 5
                        nigragillin 0
                        trans,trans-2,4-hexadienoyl-CoA 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19754
    subatomic particle 19752
      composite particle 19752
        hadron 19752
          baryon 19752
            nucleon 19752
              atomic nucleus 19752
                atom 19752
                  main group element atom 19637
                    p-block element atom 19637
                      carbon group element atom 19528
                        carbon atom 19517
                          organic molecular entity 19517
                            organic group 18422
                              organic divalent group 18414
                                organodiyl group 18414
                                  carbonyl group 18303
                                    carbonyl compound 18303
                                      carboxylic acid 17971
                                        monocarboxylic acid 17286
                                          fatty acid 15829
                                            unsaturated fatty acid 898
                                              polyunsaturated fatty acid 653
                                                hexadienoic acid 5
                                                  sorbic acid 5
                                                    (2E,4E)-hexa-2,4-dienoic acid 5
                                                      nigragillin 0
                                                      trans,trans-2,4-hexadienoyl-CoA 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.