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Term:(2E,4E)-hexa-2,4-dienoic acid
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Accession:CHEBI:38358 term browser browse the term
Definition:A sorbic acid having trans-double bonds at positions 2 and 4; a food preservative that can induce cutaneous vasodilation and stinging upon topical application to humans. It is the most thermodynamically stable of the four possible geometric isomers possible, as well as the one with the highest antimicrobial activity.
Synonyms:related_synonym: (2E,4E)-2,4-hexadienoic acid;   (E,E)-1,3-pentadiene-1-carboxylic acid;   (E,E)-2,4-hexadienoic acid;   (E,E)-SA;   (E,E)-sorbic acid;   1,3-pentadiene-1-carboxylic acid;   Formula=C6H8O2;   InChI=1S/C6H8O2/c1-2-3-4-5-6(7)8/h2-5H,1H3,(H,7,8)/b3-2+,5-4+;   InChIKey=WSWCOQWTEOXDQX-MQQKCMAXSA-N;   SA;   SMILES=C\\C=C\\C=C\\C(O)=O;   alpha-trans-gamma-trans-sorbic acid;   trans,trans-2,4-hexadienoic acid;   trans,trans-SA;   trans,trans-sorbic acid
 xref: Beilstein:1098547 "Beilstein";   CAS:110-44-1 "ChemIDplus";   CAS:110-44-1 "NIST Chemistry WebBook";   Gmelin:260824 "Gmelin";   Gmelin:3063 "Gmelin";   LIPID_MAPS_instance:LMFA01030100 "LIPID MAPS"
 xref_mesh: MESH:D013011
 xref: PMID:11206806 "Europe PMC";   PMID:7979442 "Europe PMC"
 cyclic_relationship: is_conjugate_acid_of CHEBI:77869

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(2E,4E)-hexa-2,4-dienoic acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fosl1 fos-like antigen 1 JBrowse link 19 5,447,698 5,455,938 RGD:6480464
G Orm1 orosomucoid 1 JBrowse link 4 63,344,556 63,348,163 RGD:6480464
G Phex phosphate regulating endopeptidase homolog, X-linked JBrowse link X 157,162,075 157,415,286 RGD:6480464
G Rad51ap1 RAD51 associated protein 1 JBrowse link 6 126,923,415 126,939,621 RGD:6480464
G Vegfa vascular endothelial growth factor A JBrowse link 17 46,016,993 46,032,377 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 21264
    chemical entity 21262
      atom 21260
        nonmetal atom 21104
          carbon atom 20791
            organic molecular entity 20791
              lipid 17698
                fatty acid 16417
                  medium-chain fatty acid 2872
                    sorbic acid 5
                      (2E,4E)-hexa-2,4-dienoic acid 5
                        nigragillin 0
                        trans,trans-2,4-hexadienoyl-CoA 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 21264
    subatomic particle 21260
      composite particle 21260
        hadron 21260
          baryon 21260
            nucleon 21260
              atomic nucleus 21260
                atom 21260
                  main group element atom 21128
                    p-block element atom 21128
                      carbon group element atom 20901
                        carbon atom 20791
                          organic molecular entity 20791
                            organic group 19184
                              organic divalent group 19174
                                organodiyl group 19174
                                  carbonyl group 19146
                                    carbonyl compound 19146
                                      carboxylic acid 18823
                                        monocarboxylic acid 18015
                                          fatty acid 16417
                                            unsaturated fatty acid 907
                                              polyunsaturated fatty acid 659
                                                hexadienoic acid 5
                                                  sorbic acid 5
                                                    (2E,4E)-hexa-2,4-dienoic acid 5
                                                      nigragillin 0
                                                      trans,trans-2,4-hexadienoyl-CoA 0
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.