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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:[N-(4-cyanophenyl)-N'-(diphenylmethyl)guanidine]acetic acid
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Accession:CHEBI:385425 term browser browse the term
Definition:A trisubstituted guanidine, carrying 4-cyanophenyl, diphenylmethyl and carboxymethyl substituents, which is known to act as a highly potent sweetening agent.
Synonyms:exact_synonym: (Z)-N-{[(4-cyanophenyl)amino][(diphenylmethyl)amino]methylidene}glycine
 related_synonym: 2-[[(benzhydrylamino)-[(4-cyanophenyl)amino]methylidene]amino]ethanoic acid;   CP-Dpm-GA;   Formula=C23H20N4O2;   InChI=1S/C23H20N4O2/c24-15-17-11-13-20(14-12-17)26-23(25-16-21(28)29)27-22(18-7-3-1-4-8-18)19-9-5-2-6-10-19/h1-14,22H,16H2,(H,28,29)(H2,25,26,27);   InChIKey=KGHMYJFHUHFOGL-UHFFFAOYSA-N;   N-(4-Cyanophenyl)-N'-(diphenylmethyl)guanidineacetic acid;   N-(P-CYANOPHENYL)-N'-DIPHENYLMETHYL-GUANIDINE-ACETIC ACID;   N-(p-Cyanophenyl)-N'-(diphenylmethyl)-N''-(carboxymethyl)guanidine;   NC-174;   SMILES=OC(=O)C\\N=C(\\NC(c1ccccc1)c1ccccc1)Nc1ccc(cc1)C#N
 alt_id: CHEBI:42679
 xref: CAS:138460-25-0;   DrugBank:DB07816
 xref_mesh: MESH:C083643
 xref: PDB:1ETZ;   PDB:2CGR;   PDBeChem:GAS;   PMID:10993728;   PMID:7893280;   PMID:9871559;   Reaxys:25965952


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[N-(4-cyanophenyl)-N'-(diphenylmethyl)guanidine]acetic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gnat3 G protein subunit alpha transducin 3 affects response to substance ISO GNAT3 protein affects the susceptibility to NC 174 CTD PMID:16740645 NCBI chr 4:13,827,764...13,878,126
Ensembl chr 4:13,827,756...13,878,126
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  CHEBI ontology 19816
    role 19764
      biological role 19764
        epitope 6842
          [N-(4-cyanophenyl)-N'-(diphenylmethyl)guanidine]acetic acid 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19816
    subatomic particle 19814
      composite particle 19814
        hadron 19814
          baryon 19814
            nucleon 19814
              atomic nucleus 19814
                atom 19814
                  main group element atom 19702
                    p-block element atom 19702
                      carbon group element atom 19608
                        carbon atom 19597
                          organic molecular entity 19597
                            organic group 18537
                              organic divalent group 18530
                                organodiyl group 18530
                                  carbonyl group 18436
                                    carbonyl compound 18436
                                      carboxylic acid 18114
                                        amino acid 14085
                                          alpha-amino acid 11550
                                            L-alpha-amino acid 11385
                                              serine family amino acid 1878
                                                glycine 972
                                                  glycine derivative 961
                                                    [N-(4-cyanophenyl)-N'-(diphenylmethyl)guanidine]acetic acid 1
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