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ONTOLOGY REPORT - ANNOTATIONS


Term:3-methyladenine
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Accession:CHEBI:38635 term browser browse the term
Definition:A methyladenine that is adenine substituted with a methyl group at position N-3.
Synonyms:related_synonym: 3-METHYL-3H-PURIN-6-YLAMINE;   3-Methyl-3H-Purin-6-amine;   3-methyl-3H-adenine;   6-amino-3-methylpurine;   Formula=C6H7N5;   InChI=1S/C6H7N5/c1-11-3-10-5(7)4-6(11)9-2-8-4/h2-3H,7H2,1H3;   InChIKey=FSASIHFSFGAIJM-UHFFFAOYSA-N;   SMILES=Cn1cnc(N)c2ncnc12
 alt_id: CHEBI:1590;   CHEBI:21828;   CHEBI:40596
 xref: Beilstein:146087 "Beilstein";   CAS:5142-23-4 "ChemIDplus";   CAS:5142-23-4 "KEGG COMPOUND";   CAS:5142-23-4 "NIST Chemistry WebBook";   DrugBank:DB04104;   Gmelin:279109 "Gmelin";   HMDB:HMDB0011600;   KEGG:C00913;   LINCS:LSM-4733
 xref_mesh: MESH:C025946
 xref: MetaCyc:3-Methyl-Adenines;   PDBeChem:ADK;   PMID:16139832 "Europe PMC";   PMID:22770225 "Europe PMC";   PMID:23819759 "Europe PMC";   PMID:24297644 "Europe PMC";   PMID:24830781 "Europe PMC";   PMID:25708950 "Europe PMC";   Reaxys:146087 "Reaxys";   Reaxys:6503822 "Reaxys"


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3-methyladenine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acta2 actin alpha 2, smooth muscle JBrowse link 1 252,537,614 252,550,394 RGD:6480464
G Aifm1 apoptosis inducing factor, mitochondria associated 1 JBrowse link X 135,304,063 135,343,062 RGD:6480464
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:6480464
G Apod apolipoprotein D JBrowse link 11 72,705,204 72,726,263 RGD:6480464
G App amyloid beta precursor protein JBrowse link 11 24,425,013 24,641,872 RGD:6480464
G Atg4a autophagy related 4A, cysteine peptidase JBrowse link X 112,328,907 112,403,157 RGD:6480464
G Atg4b autophagy related 4B, cysteine peptidase JBrowse link 9 100,888,457 100,920,123 RGD:6480464
G Atg5 autophagy related 5 JBrowse link 20 49,301,783 49,393,147 RGD:6480464
G Atg7 autophagy related 7 JBrowse link 4 146,570,113 146,777,093 RGD:6480464
G Atp5pd ATP synthase peripheral stalk subunit d JBrowse link 10 103,967,340 103,972,552 RGD:6480464
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:6480464
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:6480464
G Bcl2l1 Bcl2-like 1 JBrowse link 3 148,259,594 148,314,191 RGD:6480464
G Becn1 beclin 1 JBrowse link 10 89,209,944 89,225,297 RGD:6480464
G Casp1 caspase 1 JBrowse link 8 2,605,743 2,614,637 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Casp4 caspase 4 JBrowse link 8 2,616,391 2,651,682 RGD:6480464
G Casp7 caspase 7 JBrowse link 1 277,190,557 277,242,779 RGD:6480464
G Casp8 caspase 8 JBrowse link 9 65,614,142 65,662,624 RGD:6480464
G Casp9 caspase 9 JBrowse link 5 160,356,211 160,373,774 RGD:6480464
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:6480464
G Cdx2 caudal type homeo box 2 JBrowse link 12 9,464,026 9,470,565 RGD:6480464
G Cebpa CCAAT/enhancer binding protein alpha JBrowse link 1 91,363,492 91,366,164 RGD:6480464
G Chek1 checkpoint kinase 1 JBrowse link 8 39,181,162 39,201,588 RGD:6480464
G Ctsb cathepsin B JBrowse link 15 46,316,741 46,337,613 RGD:6480464
G Ctsl cathepsin L JBrowse link 17 1,873,105 1,879,266 RGD:6480464
G Cxcl2 C-X-C motif chemokine ligand 2 JBrowse link 14 18,731,346 18,733,391 RGD:6480464
G Cxcl3 chemokine (C-X-C motif) ligand 3 JBrowse link 14 18,820,168 18,839,659 RGD:6480464
G Cycs cytochrome c, somatic JBrowse link 4 80,331,226 80,333,326 RGD:6480464
G Ddit3 DNA-damage inducible transcript 3 JBrowse link 7 70,578,564 70,585,074 RGD:6480464
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 JBrowse link 16 68,954,860 68,968,248 RGD:6480464
G Gabarap GABA type A receptor-associated protein JBrowse link 10 56,601,288 56,604,223 RGD:6480464
G Gap43 growth associated protein 43 JBrowse link 11 58,624,198 58,717,916 RGD:6480464
G Gsk3b glycogen synthase kinase 3 beta JBrowse link 11 65,060,884 65,208,842 RGD:6480464
G Gys1 glycogen synthase 1 JBrowse link 1 101,427,195 101,447,092 RGD:6480464
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link 6 96,810,868 96,856,303 RGD:6480464
G Hspa5 heat shock protein family A (Hsp70) member 5 JBrowse link 3 13,838,304 13,842,763 RGD:6480464
G Icam1 intercellular adhesion molecule 1 JBrowse link 8 22,035,287 22,047,049 RGD:6480464
G Il18 interleukin 18 JBrowse link 8 55,009,666 55,016,286 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Irs1 insulin receptor substrate 1 JBrowse link 9 88,033,668 88,086,488 RGD:6480464
G Itgam integrin subunit alpha M JBrowse link 1 199,495,312 199,545,738 RGD:6480464
G Lamp1 lysosomal-associated membrane protein 1 JBrowse link 16 81,689,576 81,714,341 RGD:6480464
G Lamp2 lysosomal-associated membrane protein 2 JBrowse link X 124,722,628 124,766,079 RGD:6480464
G Lgals1 galectin 1 JBrowse link 7 120,153,184 120,156,290 RGD:6480464
G Lrrk2 leucine-rich repeat kinase 2 JBrowse link 7 132,857,311 133,018,549 RGD:6480464
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha JBrowse link 3 150,801,289 150,802,935 RGD:6480464
G Map1lc3b microtubule-associated protein 1 light chain 3 beta JBrowse link 19 53,635,449 53,643,970 RGD:6480464
G Map3k5 mitogen-activated protein kinase kinase kinase 5 JBrowse link 1 15,412,603 15,613,752 RGD:6480464
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6480464
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6480464
G Mcl1 MCL1 apoptosis regulator, BCL2 family member JBrowse link 2 197,786,212 197,788,992 RGD:6480464
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:6480464
G Mpg N-methylpurine-DNA glycosylase JBrowse link 10 15,661,768 15,667,995 RGD:6480464
G Mtor mechanistic target of rapamycin kinase JBrowse link 5 165,263,813 165,373,967 RGD:6480464
G Nanog Nanog homeobox JBrowse link 4 155,531,906 155,539,268 RGD:6480464
G Ndufa1 NADH:ubiquinone oxidoreductase subunit A1 JBrowse link X 123,803,109 123,806,760 RGD:6480464
G Ndufa2 NADH:ubiquinone oxidoreductase subunit A2 JBrowse link 18 29,585,671 29,587,760 RGD:6480464
G Ndufc2 NADH:ubiquinone oxidoreductase subunit C2 JBrowse link 1 162,369,801 162,376,024 RGD:6480464
G Ndufs3 NADH:ubiquinone oxidoreductase core subunit S3 JBrowse link 3 79,721,686 79,728,863 RGD:6480464
G Ndufs4 NADH:ubiquinone oxidoreductase subunit S4 JBrowse link 2 46,372,488 46,476,162 RGD:6480464
G Nefh neurofilament heavy JBrowse link 14 85,181,572 85,191,557 RGD:6480464
G Nefl neurofilament light JBrowse link 15 44,799,378 44,803,251 RGD:6480464
G Nlrp3 NLR family, pyrin domain containing 3 JBrowse link 10 45,884,324 45,918,290 RGD:6480464
G Parp1 poly (ADP-ribose) polymerase 1 JBrowse link 13 98,857,255 98,889,444 RGD:6480464
G Pik3c3 phosphatidylinositol 3-kinase, catalytic subunit type 3 JBrowse link 18 22,964,121 23,047,896 RGD:6480464
G Pml promyelocytic leukemia JBrowse link 8 63,002,515 63,034,310 RGD:6480464
G Pou5f1 POU class 5 homeobox 1 JBrowse link 20 3,747,231 3,751,994 RGD:6480464
G Ppara peroxisome proliferator activated receptor alpha JBrowse link 7 126,618,872 126,687,282 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:6480464
G Rara retinoic acid receptor, alpha JBrowse link 10 86,838,819 86,884,224 RGD:6480464
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6480464
G Rps6kb1 ribosomal protein S6 kinase B1 JBrowse link 10 73,824,200 73,865,503 RGD:6480464
G Snca synuclein alpha JBrowse link 4 90,782,412 90,883,236 RGD:6480464
G Sox2 SRY-box transcription factor 2 JBrowse link 2 121,165,137 121,167,545 RGD:6480464
G Sqstm1 sequestosome 1 JBrowse link 10 35,704,728 35,716,316 RGD:6480464
G Th tyrosine hydroxylase JBrowse link 1 216,073,034 216,080,287 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Tomm20 translocase of outer mitochondrial membrane 20 JBrowse link 19 59,863,421 59,873,411 RGD:6480464
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:6480464
G Ulk1 unc-51 like autophagy activating kinase 1 JBrowse link 12 51,908,105 51,934,704 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19716
    role 19663
      biological role 19661
        inhibitor 18143
          autophagy inhibitor 516
            3-methyladenine 82
Path 2
Term Annotations click to browse term
  CHEBI ontology 19716
    subatomic particle 19712
      composite particle 19712
        hadron 19712
          baryon 19712
            nucleon 19712
              atomic nucleus 19712
                atom 19712
                  main group element atom 19598
                    p-block element atom 19598
                      carbon group element atom 19486
                        carbon atom 19480
                          organic molecular entity 19480
                            organic molecule 19402
                              organic cyclic compound 19158
                                organic heterocyclic compound 18245
                                  organic heteropolycyclic compound 17500
                                    organic heterobicyclic compound 15910
                                      imidazopyrimidine 5415
                                        purines 5413
                                          aminopurine 4372
                                            6-aminopurines 757
                                              adenine 751
                                                methyladenine 82
                                                  3-methyladenine 82
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.