Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:4,4'-thiodiphenol
go back to main search page
Accession:CHEBI:38957 term browser browse the term
Definition:A phenol that has formula C12H10O2S.
Synonyms:exact_synonym: 4,4'-sulfanediyldiphenol
 related_synonym: 4,4'-Dihydroxydiphenyl sulfide;   Bis(4-oxyphenyl)sulfide;   Formula=C12H10O2S;   InChI=1S/C12H10O2S/c13-9-1-5-11(6-2-9)15-12-7-3-10(14)4-8-12/h1-8,13-14H;   InChIKey=VWGKEVWFBOUAND-UHFFFAOYSA-N;   SMILES=Oc1ccc(Sc2ccc(O)cc2)cc1;   p,p'-Dihydroxydiphenyl sulfide
 xref: Beilstein:2050739;   CAS:2664-63-3
 xref_mesh: MESH:C586730


show annotations for term's descendants           Sort by:
 
4,4'-thiodiphenol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr1 estrogen receptor 1 increases expression
multiple interactions
ISO 4,4'-thiodiphenol results in increased expression of ESR1 protein
4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [4,4'-thiodiphenol results in increased expression of ESR1 protein]; fulvestrant inhibits the reaction [4,4'-thiodiphenol results in increased expression of ESR1 protein]
CTD PMID:27880919 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 multiple interactions
increases expression
ISO 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [4,4'-thiodiphenol results in increased expression of GPER1 protein]; Fulvestrant inhibits the reaction [4,4'-thiodiphenol results in increased expression of GPER1 protein] CTD PMID:27880919 NCBI chr12:17,309,122...17,315,267
Ensembl chr12:17,309,834...17,311,112
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions
ISO 4,4'-thiodiphenol results in increased phosphorylation of MAPK1 protein
4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [4,4'-thiodiphenol results in increased phosphorylation of MAPK1 protein]; fulvestrant inhibits the reaction [4,4'-thiodiphenol results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [4,4'-thiodiphenol results in increased phosphorylation of MAPK1 protein]; wortmannin inhibits the reaction [4,4'-thiodiphenol results in increased phosphorylation of MAPK1 protein]
CTD PMID:27880919 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
multiple interactions
ISO 4,4'-thiodiphenol results in increased phosphorylation of MAPK3 protein
4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [4,4'-thiodiphenol results in increased phosphorylation of MAPK3 protein]; Fulvestrant inhibits the reaction [4,4'-thiodiphenol results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [4,4'-thiodiphenol results in increased phosphorylation of MAPK3 protein]; Wortmannin inhibits the reaction [4,4'-thiodiphenol results in increased phosphorylation of MAPK3 protein]
CTD PMID:27880919 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
temephos term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dio1 iodothyronine deiodinase 1 decreases activity ISO Temefos results in decreased activity of DIO1 protein CTD PMID:30561685 NCBI chr 5:126,894,837...126,911,532
Ensembl chr 5:126,895,286...126,911,520
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO Temefos inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19816
    chemical entity 19816
      molecular entity 19814
        polyatomic entity 19727
          heteroatomic molecular entity 19653
            hydroxides 19107
              organic hydroxy compound 18661
                phenols 18145
                  4,4'-thiodiphenol 6
                    temephos 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19816
    subatomic particle 19814
      composite particle 19814
        hadron 19814
          baryon 19814
            nucleon 19814
              atomic nucleus 19814
                atom 19814
                  main group element atom 19702
                    p-block element atom 19702
                      carbon group element atom 19608
                        carbon atom 19597
                          organic molecular entity 19597
                            heteroorganic entity 19184
                              organochalcogen compound 18894
                                organosulfur compound 15223
                                  organic sulfide 8137
                                    aryl sulfide 7475
                                      diphenyl sulfide 6
                                        4,4'-thiodiphenol 6
                                          temephos 2
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.