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ONTOLOGY REPORT - ANNOTATIONS


Term:cryptolepine
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Accession:CHEBI:3930 term browser browse the term
Definition:An organic heterotetracyclic compound that is 5H-indolo[3,2-b]quinoline in which the hydrogen at position N-5 is replaced by a methyl group.
Synonyms:related_synonym: 5-METHYL-5H-INDOLO[3,2-B]QUINOLINE;   CCRIS 9019;   Formula=C16H12N2;   InChI=1S/C16H12N2/c1-18-15-9-5-2-6-11(15)10-14-16(18)12-7-3-4-8-13(12)17-14/h2-10H,1H3;   InChIKey=KURWKDDWCJELSV-UHFFFAOYSA-N;   SMILES=Cn1c2c(cc3ccccc13)nc1ccccc21
 alt_id: CHEBI:42177
 xref: CAS:480-26-2 "ChemIDplus";   CAS:480-26-2 "KEGG COMPOUND";   KEGG:C09142;   KNApSAcK:C00001710
 xref_mesh: MESH:C024015
 xref: PDBeChem:DR1;   PMID:20623717 "Europe PMC";   PMID:21369934 "Europe PMC";   PMID:21946165 "Europe PMC";   PMID:22091398 "Europe PMC";   PMID:22221099 "Europe PMC";   PMID:22436019 "Europe PMC";   PMID:22477022 "Europe PMC";   PMID:22926067 "Europe PMC";   PMID:23092722 "Europe PMC";   PMID:23507189 "Europe PMC";   PMID:23737832 "Europe PMC";   PMID:24391229 "Europe PMC";   Reaxys:15814 "Reaxys";   Wikipedia:Cryptolepine


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cryptolepine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:6480464
G Birc3 baculoviral IAP repeat-containing 3 JBrowse link 8 6,048,590 6,076,828 RGD:6480464
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase JBrowse link 3 120,373,604 120,404,910 RGD:6480464
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B JBrowse link 3 110,367,949 110,420,471 RGD:6480464
G Ccna2 cyclin A2 JBrowse link 2 123,274,727 123,282,266 RGD:6480464
G Ccnb1 cyclin B1 JBrowse link 2 30,782,133 30,791,106 RGD:6480464
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:6480464
G Cdc25c cell division cycle 25C JBrowse link 18 27,528,768 27,550,316 RGD:6480464
G Cdc34 cell division cycle 34 JBrowse link 7 12,899,957 12,905,339 RGD:6480464
G Cdc45 cell division cycle 45 JBrowse link 11 86,328,785 86,354,099 RGD:6480464
G Cdc6 cell division cycle 6 JBrowse link 10 86,819,477 86,833,301 RGD:6480464
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:6480464
G Cdkn3 cyclin-dependent kinase inhibitor 3 JBrowse link 15 23,553,171 23,564,538 RGD:6480464
G Cenpf centromere protein F JBrowse link 13 108,132,499 108,178,609 RGD:6480464
G Gdf15 growth differentiation factor 15 JBrowse link 16 20,555,395 20,557,978 RGD:6480464
G Mcm2 minichromosome maintenance complex component 2 JBrowse link 4 120,825,699 120,840,221 RGD:6480464
G Mcm6 minichromosome maintenance complex component 6 JBrowse link 13 45,042,882 45,068,073 RGD:6480464
G Mcm7 minichromosome maintenance complex component 7 JBrowse link 12 19,306,615 19,313,877 RGD:6480464
G Mcm8 minichromosome maintenance 8 homologous recombination repair factor JBrowse link 3 125,470,499 125,500,795 RGD:6480464
G Mdm2 MDM2 proto-oncogene JBrowse link 7 60,719,060 60,743,618 RGD:6480464
G Myt1 myelin transcription factor 1 JBrowse link 3 177,281,365 177,341,550 RGD:6480464
G Nek2 NIMA-related kinase 2 JBrowse link 13 110,511,546 110,524,750 RGD:6480464
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:6480464
G Ttk Ttk protein kinase JBrowse link 8 91,368,065 91,405,995 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19654
    role 19598
      application 19220
        anti-inflammatory agent 14905
          cryptolepine 24
Path 2
Term Annotations click to browse term
  CHEBI ontology 19654
    subatomic particle 19650
      composite particle 19650
        hadron 19650
          baryon 19650
            nucleon 19650
              atomic nucleus 19650
                atom 19650
                  main group element atom 19531
                    p-block element atom 19531
                      carbon group element atom 19413
                        carbon atom 19405
                          organic molecular entity 19405
                            organic molecule 19327
                              organic cyclic compound 19076
                                organic heterocyclic compound 18151
                                  organic heteropolycyclic compound 17415
                                    organic heterotetracyclic compound 4324
                                      cryptolepine 24
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.