Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   


go back to main search page
Accession:CHEBI:4024 term browser browse the term
Definition:A carboxylic ester resulting from the formal condensation of (1-hydroxycyclopentyl)(phenyl)acetic acid with N,N-dimethylethanolamine. A tertiary amine antimuscarinic with actions similar to atropine, it is used as its hydrochloride salt to produce mydriasis (excessive dilation of the pupil) and cycloplegia (paralysis of the ciliary muscle of the eye) for opthalmic diagnostic procedures. It acts more quickly than atropine and has a shorter duration of action.
Synonyms:exact_synonym: 2-(dimethylamino)ethyl (1-hydroxycyclopentyl)(phenyl)acetate
 related_synonym: 1-hydroxy-alpha-phenylcyclopentaneacetic acid 2-(dimethylamino)ethyl ester;   2-(dimethylamino)ethyl 1-hydroxy-alpha-phenylcyclopentaneacetate;   2-(dimethylamino)ethyl 2-(1-hydroxycyclopentyl)-2-phenylacetate;   2-phenyl-2-(1-hydroxycyclopentyl)ethanoic acid beta-(dimethylamino)ethyl ester;   Formula=C17H25NO3;   InChI=1S/C17H25NO3/c1-18(2)12-13-21-16(19)15(14-8-4-3-5-9-14)17(20)10-6-7-11-17/h3-5,8-9,15,20H,6-7,10-13H2,1-2H3;   InChIKey=SKYSRIRYMSLOIN-UHFFFAOYSA-N;   SMILES=CN(C)CCOC(=O)C(c1ccccc1)C1(O)CCCC1;   alpha-(1-hydroxycyclopentyl)benzeneacetic acid 2-(dimethylamino)ethyl ester;   beta-(dimethylamino)ethyl (1-hydroxycyclopentyl)phenylacetate;   beta-dimethylaminoethyl (1-hydroxycyclopentyl)phenylacetate;   ciclopentolato;   cyclopentolatum
 xref: Beilstein:2147087;   CAS:512-15-2;   DrugBank:DB00979;   Drug_Central:757;   HMDB:HMDB0015114;   KEGG:C06932;   KEGG:D07759;   LINCS:LSM-1800;   Patent:US2554511;   Reaxys:2147087;   Wikipedia:Cyclopentolate

show annotations for term's descendants       view all columns           Sort by:

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19758
    role 19705
      application 19359
        curing agent 1
          N,N-dimethylethanolamine 1
            cyclopentolate 0
              (R)-cyclopentolate + 0
              (S)-cyclopentolate + 0
              cyclopentolate hydrochloride + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19758
    subatomic particle 19756
      composite particle 19756
        hadron 19756
          baryon 19756
            nucleon 19756
              atomic nucleus 19756
                atom 19756
                  main group element atom 19641
                    main group molecular entity 19641
                      s-block molecular entity 19403
                        hydrogen molecular entity 19392
                          hydrides 18362
                            inorganic hydride 17222
                              pnictogen hydride 17186
                                nitrogen hydride 17020
                                  azane 16711
                                    ammonia 16709
                                      organic amino compound 16708
                                        amino alcohol 875
                                          ethanolamines 760
                                            N,N-dimethylethanolamine 1
                                              cyclopentolate 0
                                                (R)-cyclopentolate + 0
                                                (S)-cyclopentolate + 0
                                                cyclopentolate hydrochloride + 0
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.