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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:cyclophosphamide
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Accession:CHEBI:4027 term browser browse the term
Definition:A phosphorodiamide that is 1,3,2-oxazaphosphinan-2-amine 2-oxide substituted by two 2-chloroethyl groups at the amino nitrogen atom.
Synonyms:exact_synonym: N,N-bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide
 related_synonym: (RS)-Cyclophosphamide;   2-[Bis(2-chloroethylamino)]-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide;   Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester;   Cyclophosphamide anhydrous;   Formula=C7H15Cl2N2O2P;   InChI=1S/C7H15Cl2N2O2P/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14/h1-7H2,(H,10,12);   InChIKey=CMSMOCZEIVJLDB-UHFFFAOYSA-N;   N,N-bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide;   SMILES=ClCCN(CCCl)P1(=O)NCCCO1
 xref: Beilstein:11744;   CAS:50-18-0;   DrugBank:DB00531;   Drug_Central:758;   HMDB:HMDB0014672;   KEGG:C07888;   KEGG:D07760;   LINCS:LSM-4961
 xref_mesh: MESH:D003520
 xref: PMID:15711186;   PMID:7850793;   Reaxys:11744;   Wikipedia:Cyclophosphamide


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cyclophosphamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
decreases expression
increases expression
ISO
EXP
[Cyclophosphamide results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA; ABCB1 protein affects the susceptibility to [Cyclophosphamide co-treated with Methotrexate co-treated with Fluorouracil]; ABCB1 protein affects the susceptibility to [Fluorouracil co-treated with Epirubicin co-treated with Cyclophosphamide]; NR1I2 protein promotes the reaction [Cyclophosphamide results in increased expression of ABCB1 protein]
Cyclophosphamide results in decreased expression of ABCB1 mRNA; Cyclophosphamide results in decreased expression of ABCB1A mRNA
CTD PMID:12576456, PMID:20041327, PMID:20623750, PMID:30563925 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions
decreases response to substance
ISO ABCC1 protein affects the susceptibility to [Fluorouracil co-treated with Epirubicin co-treated with Cyclophosphamide]
ABCC1 protein results in decreased susceptibility to Cyclophosphamide
CTD PMID:11778547, PMID:12576456 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions ISO ABCG2 protein affects the susceptibility to [Fluorouracil co-treated with Epirubicin co-treated with Cyclophosphamide] CTD PMID:12576456 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Abhd3 abhydrolase domain containing 3, phospholipase increases expression ISO Cyclophosphamide results in increased expression of ABHD3 mRNA CTD PMID:21527772 NCBI chr18:1,892,413...1,946,840
Ensembl chr18:1,892,413...1,946,840
JBrowse link
G Abi2 abl-interactor 2 decreases expression EXP Cyclophosphamide results in decreased expression of ABI2 mRNA CTD PMID:27466211 NCBI chr 9:67,234,612...67,284,504
Ensembl chr 9:67,234,303...67,282,600
JBrowse link
G Ace angiotensin I converting enzyme decreases expression EXP Cyclophosphamide results in decreased expression of ACE mRNA CTD PMID:27281708 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Ackr3 atypical chemokine receptor 3 increases expression EXP Cyclophosphamide results in increased expression of ACKR3 mRNA CTD PMID:20032115 NCBI chr 9:97,355,881...97,367,455
Ensembl chr 9:97,355,924...97,367,445
JBrowse link
G Acod1 aconitate decarboxylase 1 increases expression ISO Cyclophosphamide results in increased expression of ACOD1 mRNA CTD PMID:15331540 NCBI chr15:93,612,968...93,622,322
Ensembl chr15:93,612,971...93,622,358
JBrowse link
G Actb actin, beta decreases expression
affects expression
ISO
EXP
Cyclophosphamide results in decreased expression of ACTB mRNA
Cyclophosphamide affects the expression of ACTB mRNA
CTD PMID:10859244, PMID:12167460 NCBI chr12:13,715,843...13,718,813
Ensembl chr12:13,715,843...13,718,841
JBrowse link
G Adam24 a disintegrin and metallopeptidase domain 24 decreases expression EXP Cyclophosphamide results in decreased expression of ADAM24 mRNA CTD PMID:27281708 NCBI chr16:54,625,789...54,631,824
Ensembl chr16:54,625,847...54,628,458
JBrowse link
G Adamts9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 increases expression EXP Cyclophosphamide results in increased expression of ADAMTS9 mRNA CTD PMID:27281708 NCBI chr 4:124,660,254...124,860,997
Ensembl chr 4:124,660,262...124,858,250
JBrowse link
G Adcyap1 adenylate cyclase activating polypeptide 1 affects expression
increases expression
EXP Cyclophosphamide affects the expression of ADCYAP1 mRNA
Cyclophosphamide results in increased expression of ADCYAP1 protein
CTD PMID:9776515, PMID:10754506, PMID:18563302 NCBI chr 9:121,705,897...121,725,736
Ensembl chr 9:121,706,979...121,725,716
JBrowse link
G Adcyap1r1 ADCYAP receptor type I affects expression EXP Cyclophosphamide affects the expression of ADCYAP1R1 mRNA CTD PMID:18563302 NCBI chr 4:85,662,809...85,711,696
Ensembl chr 4:85,662,892...85,711,696
JBrowse link
G Adm adrenomedullin affects response to substance ISO ADM protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 1:175,443,189...175,447,260
Ensembl chr 1:175,445,088...175,447,259
JBrowse link
G Afp alpha-fetoprotein affects expression ISO Cyclophosphamide affects the expression of AFP protein CTD PMID:6177358 NCBI chr14:19,141,755...19,159,919
Ensembl chr14:19,141,755...19,159,923
JBrowse link
G Agl amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase affects response to substance ISO AGL protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 2:219,788,234...219,843,189
Ensembl chr 2:219,788,234...219,842,986
JBrowse link
G Akap2 A-kinase anchoring protein 2 increases expression ISO Cyclophosphamide results in increased expression of PALM2AKAP2 mRNA CTD PMID:17403535 NCBI chr 5:74,874,245...74,985,789
Ensembl chr 5:74,874,306...74,982,401
JBrowse link
G Akap8 A-kinase anchoring protein 8 increases expression EXP Cyclophosphamide results in increased expression of AKAP8 mRNA CTD PMID:27281708 NCBI chr 7:14,323,298...14,339,953
Ensembl chr 7:14,324,104...14,351,918
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
decreases expression
EXP Cyclophosphamide results in increased phosphorylation of and results in increased activity of AKT1 protein; NGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of AKT1 protein]; Plant Extracts inhibits the reaction [Cyclophosphamide results in decreased expression of AKT1 protein] CTD PMID:19996110, PMID:25446862 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Alad aminolevulinate dehydratase multiple interactions ISO [Cyclophosphamide co-treated with Carmustine co-treated with Etoposide] results in decreased activity of ALAD protein CTD PMID:19162187 NCBI chr 5:78,368,867...78,379,206
Ensembl chr 5:78,368,867...78,379,346
JBrowse link
G Alcam activated leukocyte cell adhesion molecule increases expression ISO Cyclophosphamide results in increased expression of ALCAM mRNA CTD PMID:21041162 NCBI chr11:50,780,735...50,985,083
Ensembl chr11:50,781,127...50,985,083
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 affects response to substance
increases expression
decreases response to substance
ISO ALDH1A1 protein affects the susceptibility to Cyclophosphamide
Cyclophosphamide results in increased expression of ALDH1A1 mRNA
ALDH1A1 protein results in decreased susceptibility to Cyclophosphamide
CTD PMID:12513786, PMID:17403535, PMID:18854779 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member increases expression ISO Cyclophosphamide results in increased expression of ALDH2 mRNA CTD PMID:17403535 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 affects response to substance ISO ALDH3A1 protein affects the susceptibility to Cyclophosphamide CTD PMID:18854779 NCBI chr10:47,490,168...47,499,855
Ensembl chr10:47,490,153...47,499,876
JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein decreases expression ISO Cyclophosphamide results in decreased expression of ALOX5AP mRNA CTD PMID:17403535 NCBI chr12:6,854,930...6,879,112
Ensembl chr12:6,854,920...6,879,154
JBrowse link
G Alyref Aly/REF export factor decreases expression ISO Cyclophosphamide results in decreased expression of ALYREF mRNA CTD PMID:21041162 NCBI chr10:109,768,593...109,774,639
Ensembl chr10:109,770,876...109,774,639
JBrowse link
G Amfr autocrine motility factor receptor multiple interactions ISO AMFR mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr19:11,473,538...11,509,500
Ensembl chr19:11,473,541...11,508,102
JBrowse link
G Angpt1 angiopoietin 1 increases expression ISO Cyclophosphamide results in increased expression of ANGPT1 mRNA CTD PMID:17403535 NCBI chr 7:81,338,327...81,592,459
Ensembl chr 7:81,342,280...81,592,206
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 decreases expression ISO Cyclophosphamide results in decreased expression of APAF1 mRNA CTD PMID:29445054 NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 increases expression EXP Cyclophosphamide results in increased expression of APEX1 mRNA CTD PMID:11599041 NCBI chr15:27,849,943...27,852,083
Ensembl chr15:27,849,979...27,852,082
JBrowse link
G Apob apolipoprotein B decreases expression EXP Cyclophosphamide results in decreased expression of APOB mRNA CTD PMID:18246545 NCBI chr 6:33,176,826...33,216,381
Ensembl chr 6:33,176,778...33,224,997
JBrowse link
G Apoe apolipoprotein E decreases expression
increases expression
ISO Cyclophosphamide results in decreased expression of APOE mRNA
Cyclophosphamide results in increased expression of APOE mRNA
CTD PMID:15331540, PMID:21041162 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Arg1 arginase 1 increases expression
decreases expression
affects expression
ISO
EXP
Cyclophosphamide results in increased expression of ARG1 mRNA
Cyclophosphamide results in decreased expression of ARG1 mRNA
Cyclophosphamide affects the expression of ARG1 mRNA
CTD PMID:18246545, PMID:21068404 NCBI chr 1:21,525,421...21,537,872
Ensembl chr 1:21,525,421...21,537,863
JBrowse link
G Arhgdib Rho GDP dissociation inhibitor beta increases expression ISO Cyclophosphamide results in increased expression of ARHGDIB mRNA CTD PMID:21527772 NCBI chr 4:170,913,920...170,932,789
Ensembl chr 4:170,913,923...170,932,618
JBrowse link
G Arhgef26 Rho guanine nucleotide exchange factor 26 increases expression ISO Cyclophosphamide results in increased expression of ARHGEF26 mRNA CTD PMID:20849824 NCBI chr 2:27,107,263...27,236,336
Ensembl chr 2:27,107,318...27,236,672
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) decreases expression ISO Cyclophosphamide metabolite results in decreased expression of ASNS mRNA CTD PMID:24356939 NCBI chr 4:33,742,876...33,761,106
Ensembl chr 4:33,743,364...33,761,163
JBrowse link
G Atf2 activating transcription factor 2 increases expression EXP Cyclophosphamide results in increased expression of ATF2 mRNA CTD PMID:11599041 NCBI chr 3:60,721,137...60,795,951
Ensembl chr 3:60,721,135...60,795,951
JBrowse link
G Atf5 activating transcription factor 5 decreases expression ISO Cyclophosphamide results in decreased expression of ATF5 mRNA CTD PMID:17403535 NCBI chr 1:100,807,821...100,812,410
Ensembl chr 1:100,808,241...100,810,522
JBrowse link
G Atg3 autophagy related 3 decreases expression ISO Cyclophosphamide results in decreased expression of ATG3 mRNA CTD PMID:20849824 NCBI chr11:60,585,192...60,613,706
Ensembl chr11:60,585,171...60,613,718
JBrowse link
G Atg5 autophagy related 5 decreases expression
multiple interactions
ISO Cyclophosphamide results in decreased expression of ATG5 protein
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of ATG5 protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of ATG5 protein]
CTD PMID:32151603 NCBI chr20:49,301,783...49,393,147
Ensembl chr20:49,318,308...49,393,140
JBrowse link
G Atg7 autophagy related 7 decreases expression
multiple interactions
ISO Cyclophosphamide results in decreased expression of ATG7 protein
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of ATG7 protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of ATG7 protein]
CTD PMID:32151603 NCBI chr 4:146,570,113...146,777,093
Ensembl chr 4:146,598,413...146,777,124
JBrowse link
G Aurkb aurora kinase B increases expression EXP Cyclophosphamide results in increased expression of AURKB mRNA CTD PMID:11599041 NCBI chr10:55,625,860...55,632,399
Ensembl chr10:55,626,741...55,634,991
JBrowse link
G Axl Axl receptor tyrosine kinase increases expression ISO Cyclophosphamide results in increased expression of AXL mRNA CTD PMID:21527772 NCBI chr 1:82,550,892...82,580,761
Ensembl chr 1:82,549,420...82,580,761
JBrowse link
G B3galnt2 beta-1,3-N-acetylgalactosaminyltransferase 2 increases expression ISO Cyclophosphamide results in increased expression of B3GALNT2 mRNA CTD PMID:21527772 NCBI chr17:54,027,859...54,070,399
Ensembl chr17:54,027,859...54,070,399
JBrowse link
G Bad BCL2-associated agonist of cell death increases expression
multiple interactions
EXP
ISO
Cyclophosphamide results in increased expression of BAD mRNA
Cyclophosphamide results in increased expression of BAD protein
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in increased expression of BAD protein]
CTD PMID:11599041, PMID:29753871 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bag1 BAG cochaperone 1 multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] affects the expression of BAG1 mRNA CTD PMID:16322899 NCBI chr 5:57,254,421...57,267,002
Ensembl chr 5:57,254,421...57,267,002
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
EXP
ISO
Cyclophosphamide results in increased expression of BAX mRNA; Cyclophosphamide results in increased expression of BAX protein
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in increased expression of BAX protein]; ganoderic acid A inhibits the reaction [Cyclophosphamide results in increased expression of BAX protein]
Plant Extracts inhibits the reaction [Cyclophosphamide results in increased expression of BAX mRNA]; sacubitril-valsartan inhibits the reaction [Cyclophosphamide results in increased expression of BAX protein]; Valsartan inhibits the reaction [Cyclophosphamide results in increased expression of BAX protein]
CTD PMID:25446862, PMID:29753871, PMID:30506662, PMID:32197949 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression
multiple interactions
EXP Cyclophosphamide results in increased expression of BBC3 mRNA
sacubitril-valsartan inhibits the reaction [Cyclophosphamide results in increased expression of BBC3 mRNA]; Valsartan inhibits the reaction [Cyclophosphamide results in increased expression of BBC3 mRNA]
CTD PMID:32197949 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Bbs4 Bardet-Biedl syndrome 4 multiple interactions ISO BBS4 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 8:64,115,005...64,154,432
Ensembl chr 8:64,121,392...64,154,396
JBrowse link
G Bche butyrylcholinesterase multiple interactions
decreases activity
ISO [Melphalan co-treated with Thiotepa co-treated with Cyclophosphamide] results in decreased expression of BCHE protein
Cyclophosphamide results in decreased activity of BCHE protein
CTD PMID:4672170, PMID:4959505 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
increases expression
ISO
EXP
[Cladribine co-treated with Cyclophosphamide co-treated with Mitoxantrone] results in decreased expression of BCL2 protein; [Cladribine co-treated with Cyclophosphamide] results in decreased expression of BCL2 protein; [Doxorubicin co-treated with Cyclophosphamide] affects the expression of BCL2 mRNA; [Doxorubicin co-treated with Dexamethasone co-treated with Vincristine co-treated with Cytarabine co-treated with Mercaptopurine co-treated with Methotrexate co-treated with Cyclophosphamide co-treated with Enzymes and Coenzymes] results in increased expression of BCL2 protein; BCL2 protein inhibits the reaction [Cyclophosphamide results in increased activity of CASP3 protein]; BCL2 protein inhibits the reaction [Cyclophosphamide results in increased activity of CASP9 protein]
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of BCL2 protein]; ganoderic acid A inhibits the reaction [Cyclophosphamide results in decreased expression of BCL2 protein]
Plant Extracts inhibits the reaction [Cyclophosphamide results in decreased expression of BCL2 mRNA]; sacubitril-valsartan inhibits the reaction [Cyclophosphamide results in decreased expression of BCL2 protein]; Valsartan inhibits the reaction [Cyclophosphamide results in decreased expression of BCL2 protein]
Cyclophosphamide results in decreased expression of BCL2 mRNA; Cyclophosphamide results in decreased expression of BCL2 protein
Cyclophosphamide results in increased expression of BCL2 mRNA
CTD PMID:11723234, PMID:14503796, PMID:15582267, PMID:16322899, PMID:21182165, PMID:25446862, PMID:29753871, PMID:30506662, PMID:32197949 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression EXP Cyclophosphamide results in increased expression of BCL2L1 mRNA CTD PMID:11599041 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bcl2l11 BCL2 like 11 increases expression
multiple interactions
EXP Cyclophosphamide results in increased expression of BCL2L11 mRNA
sacubitril-valsartan inhibits the reaction [Cyclophosphamide results in increased expression of BCL2L11 mRNA]; Valsartan inhibits the reaction [Cyclophosphamide results in increased expression of BCL2L11 mRNA]
CTD PMID:32197949 NCBI chr 3:120,726,906...120,764,192
Ensembl chr 3:120,726,906...120,764,192
JBrowse link
G Bcl2l2 Bcl2-like 2 increases expression ISO Cyclophosphamide results in increased expression of BCL2L2 mRNA CTD PMID:21041162 NCBI chr15:33,543,774...33,549,165
Ensembl chr15:33,544,312...33,549,164
JBrowse link
G Bcl6 BCL6, transcription repressor decreases expression ISO Cyclophosphamide results in decreased expression of BCL6 mRNA
Cyclophosphamide metabolite results in decreased expression of BCL6 mRNA
CTD PMID:21041162, PMID:24356939 NCBI chr11:80,255,790...80,279,075
Ensembl chr11:80,255,790...80,279,075
JBrowse link
G Bdh1 3-hydroxybutyrate dehydrogenase 1 affects response to substance ISO BDH1 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr11:72,577,547...72,619,435
Ensembl chr11:72,578,533...72,614,176
JBrowse link
G Bdkrb1 bradykinin receptor B1 increases expression EXP Cyclophosphamide results in increased expression of BDKRB1 mRNA CTD PMID:10498854, PMID:15576455 NCBI chr 6:129,437,423...129,441,553
Ensembl chr 6:129,438,158...129,440,574
JBrowse link
G Bdkrb2 bradykinin receptor B2 affects expression EXP Cyclophosphamide affects the expression of BDKRB2 mRNA CTD PMID:15576455 NCBI chr 6:129,399,468...129,429,676
Ensembl chr 6:129,399,468...129,429,676
JBrowse link
G Bdnf brain-derived neurotrophic factor increases expression EXP Cyclophosphamide results in increased expression of BDNF mRNA CTD PMID:10683293 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Becn1 beclin 1 multiple interactions
decreases expression
ISO BECN1 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide]
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of BECN1 protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of BECN1 protein]
CTD PMID:16896004, PMID:32151603 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Bik BCL2-interacting killer decreases expression ISO Cyclophosphamide results in decreased expression of BIK mRNA CTD PMID:17403535 NCBI chr 7:124,390,924...124,410,449
Ensembl chr 7:124,391,432...124,410,447
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of BIRC3 mRNA CTD PMID:24356939 NCBI chr 8:6,048,590...6,076,828
Ensembl chr 8:6,048,969...6,076,598
JBrowse link
G Blvrb biliverdin reductase B decreases expression EXP Cyclophosphamide results in decreased expression of BLVRB protein CTD PMID:9006340 NCBI chr 1:84,256,063...84,273,726
Ensembl chr 1:84,256,159...84,274,075
JBrowse link
G Bpi bactericidal/permeability-increasing protein decreases expression ISO Cyclophosphamide results in decreased expression of BPI mRNA CTD PMID:17403535 NCBI chr 3:154,741,627...154,768,584
Ensembl chr 3:154,741,631...154,768,640
JBrowse link
G Brpf1 bromodomain and PHD finger containing, 1 increases expression EXP Cyclophosphamide results in increased expression of BRPF1 mRNA CTD PMID:27281708 NCBI chr 4:145,264,445...145,280,943
Ensembl chr 4:145,264,462...145,280,857
JBrowse link
G Bscl2 BSCL2 lipid droplet biogenesis associated, seipin increases expression ISO Cyclophosphamide results in increased expression of BSCL2 mRNA CTD PMID:22003191 NCBI chr 1:225,035,956...225,046,137
Ensembl chr 1:225,037,737...225,046,040
JBrowse link
G Bsg basigin (Ok blood group) decreases expression ISO Cyclophosphamide results in decreased expression of BSG mRNA CTD PMID:15331540 NCBI chr 7:12,875,536...12,882,753
Ensembl chr 7:12,875,537...12,882,753
JBrowse link
G Btg1 BTG anti-proliferation factor 1 decreases expression ISO Cyclophosphamide results in decreased expression of BTG1 mRNA CTD PMID:21041162 NCBI chr 7:37,812,831...37,815,088
Ensembl chr 7:37,812,831...37,815,088
JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO Cyclophosphamide results in increased expression of BTG2 mRNA CTD PMID:29445054 NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982
JBrowse link
G Btg3 BTG anti-proliferation factor 3 multiple interactions ISO BTG3 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr11:16,873,642...16,889,100
Ensembl chr11:16,873,646...16,889,201
JBrowse link
G Bub3 BUB3 mitotic checkpoint protein multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] affects the expression of BUB3 mRNA CTD PMID:16322899 NCBI chr 1:203,526,853...203,537,459
Ensembl chr 1:203,524,426...203,557,337
JBrowse link
G C1qa complement C1q A chain increases expression ISO Cyclophosphamide results in increased expression of C1QA mRNA CTD PMID:21041162 NCBI chr 5:155,261,254...155,264,101
Ensembl chr 5:155,261,250...155,264,143
JBrowse link
G C3 complement C3 increases expression ISO Cyclophosphamide results in increased expression of C3 mRNA CTD PMID:21041162 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G Ca12 carbonic anhydrase 12 multiple interactions ISO CA12 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 8:72,405,770...72,461,425
Ensembl chr 8:72,405,748...72,460,240
JBrowse link
G Cabp1 calcium binding protein 1 decreases expression EXP Cyclophosphamide results in decreased expression of CABP1 mRNA CTD PMID:11906922 NCBI chr12:47,185,449...47,209,785
Ensembl chr12:47,179,664...47,209,784
JBrowse link
G Cabp2 calcium binding protein 2 decreases expression EXP Cyclophosphamide results in decreased expression of CABP2 mRNA CTD PMID:11906922 NCBI chr 1:219,329,186...219,335,046
Ensembl chr 1:219,329,574...219,335,043
JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H increases expression
multiple interactions
ISO Cyclophosphamide results in increased expression of CACNA1H protein
3-cyanoalanine inhibits the reaction [[N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Cyclophosphamide] results in increased expression of CACNA1H protein]; [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Cyclophosphamide] results in increased expression of CACNA1H protein
CTD PMID:29129814 NCBI chr10:14,730,932...14,789,201
Ensembl chr10:14,730,941...14,788,617
JBrowse link
G Calr calreticulin increases expression
decreases expression
EXP Cyclophosphamide results in increased expression of CALR mRNA
Cyclophosphamide results in decreased expression of CALR mRNA
CTD PMID:11599041, PMID:11906922, PMID:18246545 NCBI chr19:25,956,771...25,961,666
Ensembl chr19:25,956,771...25,961,666
JBrowse link
G Canx calnexin decreases expression EXP Cyclophosphamide results in decreased expression of CANX mRNA CTD PMID:11906922 NCBI chr10:35,800,942...35,833,939
Ensembl chr10:35,800,942...35,833,861
JBrowse link
G Capn2 calpain 2 increases expression ISO Cyclophosphamide results in increased expression of CAPN2 mRNA CTD PMID:21041162 NCBI chr13:100,878,649...100,928,811
Ensembl chr13:100,878,650...100,928,811
JBrowse link
G Car2 carbonic anhydrase 2 decreases expression
increases expression
ISO Cyclophosphamide results in decreased expression of CA2 mRNA
Cyclophosphamide results in increased expression of CAR2 mRNA
CTD PMID:15331540, PMID:17403535 NCBI chr 2:88,097,740...88,112,868
Ensembl chr 2:88,097,720...88,113,029
JBrowse link
G Car7 carbonic anhydrase 7 decreases expression EXP Cyclophosphamide results in decreased expression of CAR7 mRNA CTD PMID:27281708 NCBI chr19:636,545...645,935
Ensembl chr19:636,545...645,937
JBrowse link
G Cars cysteinyl-tRNA synthetase decreases expression ISO Cyclophosphamide metabolite results in decreased expression of CARS1 mRNA CTD PMID:24356939 NCBI chr 1:216,759,367...216,801,652
Ensembl chr 1:216,759,366...216,801,656
JBrowse link
G Casp1 caspase 1 decreases expression
increases expression
ISO Cyclophosphamide results in decreased expression of CASP1 mRNA
Cyclophosphamide results in increased expression of CASP1 mRNA
CTD PMID:17403535, PMID:21041162 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
increases expression
decreases response to substance
ISO
EXP
[Bortezomib co-treated with oblimersen co-treated with Cyclophosphamide] results in increased activity of CASP3 protein; BCL2 protein inhibits the reaction [Cyclophosphamide results in increased activity of CASP3 protein]; Cyclophosphamide results in increased cleavage of and results in increased activity of CASP3 protein
sacubitril-valsartan inhibits the reaction [Cyclophosphamide results in increased activity of CASP3 protein]; Valsartan inhibits the reaction [Cyclophosphamide results in increased activity of CASP3 protein]
Cyclophosphamide results in increased expression of CASP3 protein
ganoderic acid A inhibits the reaction [Cyclophosphamide results in increased expression of CASP3 protein]
Cyclophosphamide results in increased expression of CASP3 mRNA
CASP3 protein alternative form results in decreased susceptibility to Cyclophosphamide
CTD PMID:11723234, PMID:14503796, PMID:16675587, PMID:17020986, PMID:17898787, PMID:30506662, PMID:32197949 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp4 caspase 4 increases cleavage
multiple interactions
EXP Cyclophosphamide results in increased cleavage of CASP4 protein
sacubitril-valsartan inhibits the reaction [Cyclophosphamide results in increased cleavage of CASP4 protein]; Valsartan inhibits the reaction [Cyclophosphamide results in increased cleavage of CASP4 protein]
CTD PMID:32197949 NCBI chr 8:2,616,391...2,651,682
Ensembl chr 8:2,635,851...2,651,652
JBrowse link
G Casp8 caspase 8 multiple interactions
increases response to substance
ISO [Methotrexate results in increased expression of CASP8 protein] which results in increased susceptibility to Cyclophosphamide metabolite; Cyclophosphamide metabolite results in increased expression of and results in increased cleavage of CASP8 protein; Cyclophosphamide results in increased cleavage of and results in increased activity of CASP8 protein
CASP8 protein results in increased susceptibility to Cyclophosphamide metabolite
CTD PMID:17898787, PMID:22010212 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 multiple interactions
increases expression
increases activity
ISO
EXP
BCL2 protein inhibits the reaction [Cyclophosphamide results in increased activity of CASP9 protein]; Cyclophosphamide results in increased cleavage of and results in increased activity of CASP9 protein
ganoderic acid A inhibits the reaction [Cyclophosphamide results in increased expression of CASP9 protein]
CTD PMID:11723234, PMID:17898787, PMID:30506662 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase decreases expression
decreases activity
affects activity
multiple interactions
EXP
ISO
Cyclophosphamide results in decreased expression of CAT protein
Cyclophosphamide results in decreased activity of CAT protein
Cyclophosphamide results in decreased expression of CAT mRNA; Cyclophosphamide results in decreased expression of CAT protein
Cyclophosphamide affects the activity of CAT protein
Buthionine Sulfoximine promotes the reaction [Cyclophosphamide results in decreased activity of CAT protein]; cinnamic acid inhibits the reaction [Cyclophosphamide affects the activity of CAT protein]; Cyclophosphamide promotes the reaction [NFE2L2 gene mutant form results in decreased expression of CAT protein]; Eicosapentaenoic Acid inhibits the reaction [Cyclophosphamide affects the activity of CAT protein]; Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased activity of CAT protein]; NFE2L2 gene mutant form promotes the reaction [Cyclophosphamide results in decreased expression of CAT protein]; Plant Extracts inhibits the reaction [Buthionine Sulfoximine promotes the reaction [Cyclophosphamide results in decreased activity of CAT protein]]; Plant Extracts inhibits the reaction [Cyclophosphamide results in decreased activity of CAT protein]; Plant Extracts inhibits the reaction [Cyclophosphamide results in decreased expression of CAT mRNA]
mangiferin inhibits the reaction [Cyclophosphamide results in decreased activity of CAT protein]; Pentoxifylline inhibits the reaction [Cyclophosphamide results in decreased activity of CAT protein]; pimagedine inhibits the reaction [Cyclophosphamide results in decreased expression of CAT protein]; Rutin inhibits the reaction [Cyclophosphamide results in decreased activity of CAT protein]; thymoquinone inhibits the reaction [Cyclophosphamide results in decreased activity of CAT protein]
CTD PMID:16076520, PMID:19107871, PMID:20052769, PMID:20957680, PMID:21772021, PMID:22285266, PMID:23542512, PMID:23695977, PMID:25753322, PMID:27633142, PMID:29753871 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccin calicin increases expression ISO Cyclophosphamide results in increased expression of CCIN protein CTD PMID:17475930 NCBI chr 5:59,452,348...59,454,235
Ensembl chr 5:59,452,348...59,454,233
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression
increases expression
EXP
ISO
Cyclophosphamide results in decreased expression of CCL2 protein
Cyclophosphamide results in increased expression of CCL2 mRNA
CTD PMID:18848347, PMID:21068404 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl25 C-C motif chemokine ligand 25 decreases expression ISO Cyclophosphamide results in decreased expression of CCL25 mRNA CTD PMID:21041162 NCBI chr12:2,429,492...2,438,928
Ensembl chr12:2,429,509...2,438,817
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 decreases expression ISO Cyclophosphamide results in decreased expression of CCL3 protein CTD PMID:21880982 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 increases expression ISO Cyclophosphamide results in increased expression of CCL7 mRNA CTD PMID:15331540, PMID:21041162 NCBI chr10:69,423,083...69,424,933
Ensembl chr10:69,423,086...69,424,979
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO Cyclophosphamide results in decreased expression of CCNA2 mRNA CTD PMID:21041162 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214
JBrowse link
G Ccnd2 cyclin D2 increases expression ISO Cyclophosphamide results in increased expression of CCND2 mRNA CTD PMID:21041162 NCBI chr 4:159,674,885...159,697,207
Ensembl chr 4:159,674,885...159,697,207
JBrowse link
G Ccnd3 cyclin D3 decreases expression ISO Cyclophosphamide results in decreased expression of CCND3 mRNA CTD PMID:21041162 NCBI chr 9:15,404,816...15,410,905
Ensembl chr 9:15,404,822...15,410,943
JBrowse link
G Ccr5 C-C motif chemokine receptor 5 increases expression ISO Cyclophosphamide results in increased expression of CCR5 mRNA CTD PMID:15331540 NCBI chr 8:133,192,398...133,215,599
Ensembl chr 8:133,197,032...133,215,614
JBrowse link
G Ccr8 C-C motif chemokine receptor 8 decreases expression ISO Cyclophosphamide results in decreased expression of CCR8 mRNA CTD PMID:17403535 NCBI chr 8:128,779,552...128,782,531
Ensembl chr 8:128,781,395...128,782,456
JBrowse link
G Ccr9 C-C motif chemokine receptor 9 decreases expression ISO Cyclophosphamide results in decreased expression of CCR9 mRNA CTD PMID:21041162 NCBI chr 8:132,827,325...132,842,130
Ensembl chr 8:132,828,091...132,842,130
JBrowse link
G Cct3 chaperonin containing TCP1 subunit 3 decreases expression EXP Cyclophosphamide results in decreased expression of CCT3 mRNA CTD PMID:11906922 NCBI chr 2:187,669,051...187,693,610
Ensembl chr 2:187,668,796...187,693,610
JBrowse link
G Cct5 chaperonin containing TCP1 subunit 5 decreases expression EXP Cyclophosphamide results in decreased expression of CCT5 mRNA CTD PMID:11906922 NCBI chr 2:84,667,578...84,678,730
Ensembl chr 2:84,667,633...84,678,790
JBrowse link
G Cct7 chaperonin containing TCP1 subunit 7 decreases expression EXP Cyclophosphamide results in decreased expression of CCT7 mRNA CTD PMID:11906922 NCBI chr 4:117,235,023...117,252,265
Ensembl chr 4:117,235,023...117,252,265
JBrowse link
G Cd14 CD14 molecule increases expression ISO Cyclophosphamide results in increased expression of CD14 mRNA CTD PMID:15331540, PMID:21041162 NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153
JBrowse link
G Cd151 CD151 molecule (Raph blood group) increases expression ISO Cyclophosphamide results in increased expression of CD151 mRNA CTD PMID:21041162 NCBI chr 1:214,446,659...214,450,668
Ensembl chr 1:214,009,784...214,013,765
Ensembl chr 1:214,009,784...214,013,765
JBrowse link
G Cd2 Cd2 molecule decreases expression ISO Cyclophosphamide results in decreased expression of CD2 mRNA CTD PMID:21041162 NCBI chr 2:203,666,706...203,680,073
Ensembl chr 2:203,666,637...203,680,083
JBrowse link
G Cd27 CD27 molecule decreases expression ISO Cyclophosphamide results in decreased expression of CD27 mRNA CTD PMID:21041162 NCBI chr 4:157,744,881...157,751,609
Ensembl chr 4:157,744,882...157,750,088
JBrowse link
G Cd28 Cd28 molecule decreases expression ISO Cyclophosphamide results in decreased expression of CD28 mRNA CTD PMID:21041162 NCBI chr 9:67,546,408...67,573,858
Ensembl chr 9:67,546,408...67,571,871
JBrowse link
G Cd38 CD38 molecule increases expression ISO Cyclophosphamide results in increased expression of CD38 mRNA CTD PMID:21041162 NCBI chr14:71,714,768...71,754,990
Ensembl chr14:71,715,269...71,754,672
JBrowse link
G Cd3d CD3d molecule decreases expression ISO Cyclophosphamide results in decreased expression of CD3D mRNA CTD PMID:21041162 NCBI chr 8:49,282,502...49,287,095
Ensembl chr 8:49,282,460...49,287,110
JBrowse link
G Cd3e CD3e molecule decreases expression ISO Cyclophosphamide results in decreased expression of CD3E mRNA CTD PMID:21041162 NCBI chr 8:49,297,604...49,309,370
Ensembl chr 8:49,297,608...49,308,806
JBrowse link
G Cd3g CD3g molecule decreases expression ISO Cyclophosphamide results in decreased expression of CD3G mRNA CTD PMID:21041162 NCBI chr 8:49,274,553...49,280,943
Ensembl chr 8:49,274,960...49,280,901
JBrowse link
G Cd4 Cd4 molecule decreases expression ISO Cyclophosphamide results in decreased expression of CD4 mRNA CTD PMID:21041162 NCBI chr 4:157,381,862...157,408,357
Ensembl chr 4:157,383,052...157,408,176
JBrowse link
G Cd40 CD40 molecule decreases expression ISO Cyclophosphamide results in decreased expression of CD40 mRNA CTD PMID:21041162 NCBI chr 3:161,519,789...161,534,943
Ensembl chr 3:161,519,743...161,534,704
JBrowse link
G Cd5 Cd5 molecule decreases expression ISO Cyclophosphamide results in decreased expression of CD5 mRNA CTD PMID:21041162 NCBI chr 1:226,770,912...226,791,861
Ensembl chr 1:226,770,744...226,791,879
JBrowse link
G Cd6 Cd6 molecule decreases expression ISO Cyclophosphamide results in decreased expression of CD6 mRNA CTD PMID:21041162 NCBI chr 1:226,848,399...226,887,259
Ensembl chr 1:226,848,403...226,887,156
JBrowse link
G Cd69 Cd69 molecule decreases expression ISO Cyclophosphamide results in decreased expression of CD69 mRNA
Cyclophosphamide metabolite results in decreased expression of CD69 mRNA
CTD PMID:21041162, PMID:24356939 NCBI chr 4:163,041,147...163,049,065
Ensembl chr 4:163,041,141...163,049,084
JBrowse link
G Cd74 CD74 molecule decreases expression ISO Cyclophosphamide results in decreased expression of CD74 mRNA CTD PMID:15331540 NCBI chr18:56,071,420...56,080,851
Ensembl chr18:56,071,478...56,080,849
JBrowse link
G Cd79b CD79b molecule decreases expression ISO Cyclophosphamide results in decreased expression of CD79B mRNA CTD PMID:15331540 NCBI chr10:94,497,445...94,500,591
Ensembl chr10:94,497,448...94,500,591
JBrowse link
G Cd83 CD83 molecule decreases expression ISO Cyclophosphamide results in decreased expression of CD83 mRNA CTD PMID:15331540 NCBI chr17:24,416,651...24,435,790
Ensembl chr17:24,416,651...24,435,790
JBrowse link
G Cd84 CD84 molecule increases expression ISO Cyclophosphamide metabolite results in increased expression of CD84 mRNA CTD PMID:24356939 NCBI chr13:90,241,369...90,283,625
Ensembl chr13:90,244,681...90,277,865
JBrowse link
G Cd8a CD8a molecule decreases expression ISO Cyclophosphamide results in decreased expression of CD8A mRNA CTD PMID:21041162 NCBI chr 4:99,217,640...99,243,352
Ensembl chr 4:99,239,115...99,243,351
JBrowse link
G Cd8b CD8b molecule decreases expression ISO Cyclophosphamide results in decreased expression of CD8B1 mRNA CTD PMID:21041162 NCBI chr 4:99,185,960...99,201,887
Ensembl chr 4:99,185,885...99,202,023
JBrowse link
G Cdc20 cell division cycle 20 increases expression EXP Cyclophosphamide results in increased expression of CDC20 mRNA CTD PMID:11599041 NCBI chr 5:137,260,728...137,264,931
Ensembl chr 5:137,260,739...137,265,015
JBrowse link
G Cdh1 cadherin 1 affects expression EXP Cyclophosphamide affects the expression of CDH1 mRNA CTD PMID:10859244 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Cdh2 cadherin 2 affects expression EXP Cyclophosphamide affects the expression of CDH2 mRNA CTD PMID:10859244 NCBI chr18:8,146,971...8,366,037
Ensembl chr18:8,146,971...8,360,684
JBrowse link
G Cdh3 cadherin 3 affects expression EXP Cyclophosphamide affects the expression of CDH3 mRNA CTD PMID:10859244 NCBI chr19:38,668,957...38,719,801
Ensembl chr19:38,669,230...38,719,677
JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression ISO Cyclophosphamide results in decreased expression of CDK2 mRNA CTD PMID:21041162 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO Cyclophosphamide results in increased expression of CDKN1A mRNA CTD PMID:15331540, PMID:21527772, PMID:29445054 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] affects the expression of CDKN1B mRNA CTD PMID:16322899 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C increases expression ISO Cyclophosphamide results in increased expression of CDKN1C mRNA CTD PMID:21041162 NCBI chr 1:216,661,067...216,663,791
Ensembl chr 1:216,661,080...216,663,721
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta decreases expression ISO Cyclophosphamide metabolite results in decreased expression of CEBPB mRNA CTD PMID:24356939 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Cel carboxyl ester lipase increases expression ISO Cyclophosphamide results in increased expression of CEL mRNA CTD PMID:21527772 NCBI chr 3:7,134,021...7,141,522
Ensembl chr 3:7,134,021...7,141,522
JBrowse link
G Cfb complement factor B increases expression ISO Cyclophosphamide results in increased expression of CFB mRNA CTD PMID:21041162 NCBI chr20:4,536,206...4,542,073
Ensembl chr20:4,536,203...4,561,066
Ensembl chr20:4,536,203...4,561,066
JBrowse link
G Cfi complement factor I affects response to substance ISO CFI protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 2:235,264,149...235,305,779
Ensembl chr 2:235,264,219...235,305,781
JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of CHAC1 mRNA; Cyclophosphamide results in decreased expression of CHAC1 mRNA CTD PMID:23824090, PMID:24356939 NCBI chr 3:111,160,205...111,163,425
Ensembl chr 3:111,160,205...111,163,425
JBrowse link
G Champ1 chromosome alignment maintaining phosphoprotein 1 increases expression EXP Cyclophosphamide results in increased expression of CHAMP1 mRNA CTD PMID:27281708 NCBI chr16:80,839,373...80,850,340
Ensembl chr16:80,839,374...80,850,340
JBrowse link
G Chd5 chromodomain helicase DNA binding protein 5 decreases expression EXP Cyclophosphamide results in decreased expression of CHD5 mRNA CTD PMID:27281708 NCBI chr 5:169,519,212...169,572,059
Ensembl chr 5:169,519,212...169,567,107
JBrowse link
G Chga chromogranin A decreases expression ISO Cyclophosphamide results in decreased expression of CHGA mRNA CTD PMID:15331540 NCBI chr 6:126,434,226...126,445,569
Ensembl chr 6:126,434,226...126,445,568
JBrowse link
G Chrm5 cholinergic receptor, muscarinic 5 increases expression EXP Cyclophosphamide results in increased expression of CHRM5 protein CTD PMID:16125470 NCBI chr 3:103,966,451...104,018,815
Ensembl chr 3:103,966,451...104,018,861
JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 affects expression
decreases expression
EXP Cyclophosphamide affects the expression of CITED2 mRNA
Cyclophosphamide results in decreased expression of CITED2 mRNA
CTD PMID:18246545 NCBI chr 1:12,823,363...12,825,806
Ensembl chr 1:12,823,363...12,825,786
JBrowse link
G Cldn1 claudin 1 multiple interactions
decreases expression
ISO Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of CLDN1 protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of CLDN1 protein] CTD PMID:32151603 NCBI chr11:77,815,216...77,830,373
Ensembl chr11:77,815,181...77,830,416
JBrowse link
G Cldn4 claudin 4 multiple interactions
decreases expression
EXP Anthocyanins inhibits the reaction [Cyclophosphamide results in decreased expression of CLDN4 protein]; Plant Extracts inhibits the reaction [Cyclophosphamide results in decreased expression of CLDN4 protein] CTD PMID:25451569 NCBI chr12:24,761,210...24,763,008
Ensembl chr12:24,761,210...24,763,005
JBrowse link
G Clic4 chloride intracellular channel 4 increases expression ISO Cyclophosphamide results in increased expression of CLIC4 mRNA CTD PMID:15331540 NCBI chr 5:153,568,937...153,625,669
Ensembl chr 5:153,568,745...153,625,869
JBrowse link
G Clip1 CAP-GLY domain containing linker protein 1 decreases expression EXP Cyclophosphamide results in decreased expression of CLIP1 mRNA CTD PMID:27281708 NCBI chr12:38,345,203...38,452,650
Ensembl chr12:38,345,456...38,452,652
JBrowse link
G Coch cochlin affects response to substance ISO COCH protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 6:72,359,702...72,373,710
Ensembl chr 6:72,359,791...72,373,695
JBrowse link
G Comt catechol-O-methyltransferase increases expression ISO Cyclophosphamide results in increased expression of COMT mRNA CTD PMID:21041162 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Cox7a2 cytochrome c oxidase subunit 7A2 decreases expression ISO Cyclophosphamide results in decreased expression of COX7A2 mRNA CTD PMID:17403535 NCBI chr 8:87,209,529...87,213,627
Ensembl chr 8:87,209,530...87,213,627
JBrowse link
G Crabp2 cellular retinoic acid binding protein 2 increases expression ISO Cyclophosphamide results in increased expression of CRABP2 mRNA CTD PMID:21527772 NCBI chr 2:187,322,416...187,326,794
Ensembl chr 2:184,882,969...184,883,505
JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases expression ISO Cyclophosphamide results in increased expression of CREB1 protein modified form CTD PMID:18299998 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Crem cAMP responsive element modulator decreases expression
multiple interactions
EXP Cyclophosphamide results in decreased expression of CREM mRNA; Cyclophosphamide results in decreased expression of CREM protein
Drugs, Chinese Herbal inhibits the reaction [Cyclophosphamide results in decreased expression of CREM mRNA]; Drugs, Chinese Herbal inhibits the reaction [Cyclophosphamide results in decreased expression of CREM protein]
CTD PMID:17624719 NCBI chr17:57,021,704...57,090,888
Ensembl chr17:57,031,766...57,090,888
JBrowse link
G Crh corticotropin releasing hormone increases expression EXP
ISO
Cyclophosphamide results in increased expression of CRH mRNA; Cyclophosphamide results in increased expression of CRH protein CTD PMID:15276878, PMID:16614059, PMID:17335920 NCBI chr 2:104,459,999...104,461,863
Ensembl chr 2:104,459,999...104,461,863
JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 increases expression EXP Cyclophosphamide results in increased expression of CRHR2 protein CTD PMID:16614059 NCBI chr 4:85,286,371...85,329,374
Ensembl chr 4:85,286,372...85,329,362
JBrowse link
G Csf1 colony stimulating factor 1 multiple interactions ISO [Cyclophosphamide co-treated with Sizofiran] results in increased expression of CSF1 mRNA CTD PMID:10052129 NCBI chr 2:210,522,370...210,550,546
Ensembl chr 2:210,522,375...210,550,560
JBrowse link
G Csf2 colony stimulating factor 2 affects activity
increases expression
ISO
EXP
CSF2 protein affects the activity of Cyclophosphamide
Cyclophosphamide results in increased expression of CSF2 protein
CTD PMID:8349185, PMID:18848347 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
JBrowse link
G Csk C-terminal Src kinase decreases expression ISO Cyclophosphamide results in decreased expression of CSK mRNA CTD PMID:21041162 NCBI chr 8:62,405,714...62,424,707
Ensembl chr 8:62,405,715...62,424,303
JBrowse link
G Cst7 cystatin F decreases expression ISO Cyclophosphamide results in decreased expression of CST7 mRNA CTD PMID:17403535 NCBI chr 3:146,363,913...146,373,365
Ensembl chr 3:146,365,092...146,373,365
JBrowse link
G Csta cystatin A decreases expression ISO Cyclophosphamide metabolite results in decreased expression of CSTA mRNA CTD PMID:24356939 NCBI chr11:67,555,792...67,566,980
Ensembl chr11:67,555,658...67,566,972
JBrowse link
G Cth cystathionine gamma-lyase increases expression ISO Cyclophosphamide results in increased expression of CTH protein CTD PMID:29129814 NCBI chr 2:264,266,959...264,293,040
Ensembl chr 2:264,266,984...264,293,046
JBrowse link
G Ctnnbip1 catenin, beta-interacting protein 1 multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] affects the expression of CTNNBIP1 mRNA CTD PMID:16322899 NCBI chr 5:166,464,170...166,513,030
Ensembl chr 5:166,464,252...166,513,027
JBrowse link
G Ctnnd2 catenin delta 2 multiple interactions ISO CTNND2 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 2:83,227,247...84,094,315
Ensembl chr 2:83,393,282...84,094,315
JBrowse link
G Ctsd cathepsin D multiple interactions
increases activity
ISO
EXP
[Cyclophosphamide co-treated with Mecamylamine] results in increased expression of CTSD mRNA
Cyclophosphamide results in increased activity of CTSD protein
Anthocyanins inhibits the reaction [Cyclophosphamide results in increased activity of CTSD protein]; Plant Extracts inhibits the reaction [Cyclophosphamide results in increased activity of CTSD protein]
CTD PMID:18433785, PMID:25451569 NCBI chr 1:215,541,570...215,553,446
Ensembl chr 1:215,541,542...215,553,451
JBrowse link
G Ctsh cathepsin H increases expression ISO Cyclophosphamide results in increased expression of CTSH mRNA CTD PMID:17403535 NCBI chr 8:97,439,155...97,458,293
Ensembl chr 8:97,439,161...97,458,287
JBrowse link
G Ctsl cathepsin L increases expression
decreases expression
multiple interactions
ISO Cyclophosphamide results in increased expression of CTSL mRNA
Cyclophosphamide results in decreased expression of CTSL mRNA
5-(N-methyl-N-propargylaminomethyl)-8-hydroxyquinoline inhibits the reaction [Cyclophosphamide results in decreased expression of CTSL mRNA]
CTD PMID:17403535, PMID:30760223 NCBI chr17:1,873,105...1,879,266
Ensembl chr17:1,872,848...1,879,279
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 increases expression EXP Cyclophosphamide results in increased expression of CX3CL1 protein CTD PMID:16651033 NCBI chr19:10,644,267...10,654,861
Ensembl chr19:10,644,244...10,653,800
JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 increases expression EXP Cyclophosphamide results in increased expression of CX3CR1 protein CTD PMID:16651033 NCBI chr 8:128,740,756...128,754,514
Ensembl chr 8:128,740,756...128,754,514
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 increases expression EXP Cyclophosphamide results in increased expression of CXCL1 protein CTD PMID:18848347 NCBI chr14:18,743,678...18,745,457
Ensembl chr14:18,743,685...18,745,457
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 affects expression
increases expression
increases response to substance
ISO Cyclophosphamide affects the expression of CXCL10 mRNA
Cyclophosphamide results in increased expression of CXCL10 protein
CXCL10 protein results in increased susceptibility to Cyclophosphamide
CTD PMID:18957084 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cxcl11 C-X-C motif chemokine ligand 11 increases expression ISO Cyclophosphamide results in increased expression of CXCL11 protein CTD PMID:18957084 NCBI chr14:17,195,395...17,198,170
Ensembl chr14:17,195,014...17,198,291
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 affects expression
increases expression
ISO
EXP
Cyclophosphamide affects the expression of CXCL12 mRNA
Cyclophosphamide results in increased expression of CXCL12 mRNA; Cyclophosphamide results in increased expression of CXCL12 protein
CTD PMID:12624490, PMID:16337237, PMID:19066630, PMID:20032115 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 increases expression
affects expression
multiple interactions
ISO Cyclophosphamide results in increased expression of CXCL1 mRNA; Cyclophosphamide results in increased expression of CXCL1 protein
Cyclophosphamide affects the expression of CXCL3 mRNA
VIP protein inhibits the reaction [Cyclophosphamide results in increased expression of CXCL1 protein]
CTD PMID:15331540, PMID:18483878, PMID:18957084 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 affects expression
decreases expression
increases expression
ISO Cyclophosphamide affects the expression of CXCL9 mRNA
Cyclophosphamide results in decreased expression of CXCL9 protein
Cyclophosphamide results in increased expression of CXCL9 mRNA; Cyclophosphamide results in increased expression of CXCL9 protein
CTD PMID:15331540, PMID:18957084, PMID:21041162, PMID:21880982 NCBI chr14:17,228,832...17,233,743
Ensembl chr14:17,228,856...17,234,712
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 multiple interactions
decreases expression
increases expression
affects localization
EXP
ISO
Cyclophosphamide promotes the reaction [MIF protein binds to CXCR4 protein]
Cyclophosphamide results in decreased expression of CXCR4 mRNA
Cyclophosphamide results in increased expression of CXCR4 mRNA; Cyclophosphamide results in increased expression of CXCR4 protein
Cyclophosphamide affects the localization of CXCR4 protein
CTD PMID:19066630, PMID:20032115, PMID:21041162 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878
JBrowse link
G Cxcr6 C-X-C motif chemokine receptor 6 increases expression ISO Cyclophosphamide results in increased expression of CXCR6 mRNA CTD PMID:21041162 NCBI chr 8:132,869,712...132,870,766
Ensembl chr 8:132,869,712...132,870,767
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity ISO Cyclophosphamide results in decreased activity of CYP1A1 protein CTD PMID:18420780 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity ISO Cyclophosphamide results in decreased activity of CYP1A2 protein CTD PMID:18420780 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases expression ISO Cyclophosphamide results in decreased expression of CYP1B1 mRNA CTD PMID:12167460 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions
increases expression
increases response to substance
affects metabolic processing
increases activity
increases hydroxylation
increases metabolic processing
EXP
ISO
Cyclophosphamide results in increased expression of and results in increased activity of CYP2B1 protein; Metyrapone inhibits the reaction [CYP2B1 results in increased susceptibility to Cyclophosphamide]
Cyclophosphamide results in increased expression of CYP2B10 mRNA
CYP2B1 protein results in increased susceptibility to Cyclophosphamide; CYP2B1 results in increased susceptibility to Cyclophosphamide
CYP2B1 protein affects the metabolism of Cyclophosphamide
CYP2B1 results in increased activity of Cyclophosphamide
CYP2B1 protein mutant form results in increased hydroxylation of Cyclophosphamide; CYP2B1 protein results in increased hydroxylation of Cyclophosphamide
Cyclophosphamide results in increased expression of CYP2B1 mRNA; Cyclophosphamide results in increased expression of CYP2B1 protein
CYP2B1 protein results in increased metabolism of Cyclophosphamide; CYP2B1 results in increased metabolism of Cyclophosphamide
CTD PMID:2272335, PMID:7834628, PMID:8640822, PMID:9592392, PMID:10415877, PMID:11221871, PMID:11933215, PMID:15102956, PMID:15635577, PMID:16019949, PMID:17634551, PMID:19103281, PMID:20566340, PMID:24819615 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression EXP Cyclophosphamide results in increased expression of CYP2B2 mRNA; Cyclophosphamide results in increased expression of CYP2B2 protein CTD PMID:16019949, PMID:17634551 NCBI chr 1:83,103,925...83,119,578
Ensembl chr 1:83,103,925...83,119,193
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions
increases metabolic processing
increases activity
increases response to substance
increases hydroxylation
affects hydroxylation
ISO
EXP
[Cyclophosphamide results in increased activity of NR1I3 protein alternative form] which results in increased expression of CYP2B6 mRNA; [Doxorubicin co-treated with Cyclophosphamide] affects the expression of CYP2B6 mRNA; Cyclophosphamide results in decreased expression of and results in decreased activity of CYP2B6 protein; CYP2B6 protein polymorphism affects the activity of and affects the susceptibility to Cyclophosphamide; CYP2B6 protein results in increased metabolism of and results in increased susceptibility to Cyclophosphamide; POR promotes the reaction [CYP2B6 results in increased susceptibility to Cyclophosphamide]; POR protein promotes the reaction [CYP2B6 protein results in increased susceptibility to Cyclophosphamide]
CYP2B6 protein results in increased metabolism of Cyclophosphamide
CYP2B6 protein results in increased activity of Cyclophosphamide
CYP2B6 protein results in increased susceptibility to Cyclophosphamide; CYP2B6 results in increased susceptibility to Cyclophosphamide
CYP2B6 protein results in increased hydroxylation of Cyclophosphamide
CYP2B6 intron polymorphism affects the hydroxylation of Cyclophosphamide; CYP2B6 promoter polymorphism affects the hydroxylation of Cyclophosphamide
CTD PMID:9766669, PMID:10919648, PMID:11389073, PMID:11723234, PMID:12498089, PMID:12872138, PMID:15248218, PMID:15769884, PMID:16183265, PMID:16322899, PMID:17041008, PMID:17502835, PMID:18212249, PMID:18633247, PMID:24819615, PMID:25860621 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 increases expression
increases metabolic processing
EXP Cyclophosphamide results in increased expression of CYP2C11 mRNA
CYP2C11 results in increased metabolism of Cyclophosphamide
CTD PMID:16019949, PMID:20566340 NCBI chr 1:257,676,172...258,004,428
Ensembl chr 1:257,970,345...258,004,434
JBrowse link
G Cyp2c24 cytochrome P450, family 2, subfamily c, polypeptide 24 multiple interactions
increases response to substance
increases activity
ISO POR promotes the reaction [CYP2C18 results in increased susceptibility to Cyclophosphamide]
CYP2C18 results in increased activity of Cyclophosphamide
CTD PMID:9241661, PMID:9766669 NCBI chr 1:258,074,797...258,139,176
Ensembl chr 1:258,074,860...258,139,176
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 increases metabolic processing
increases response to substance
increases hydroxylation
increases activity
multiple interactions
decreases metabolic processing
EXP
ISO
CYP2C6V1 results in increased metabolism of Cyclophosphamide
CYP2C19 protein results in increased susceptibility to Cyclophosphamide
CYP2C19 protein results in increased hydroxylation of Cyclophosphamide
CYP2C19 results in increased activity of Cyclophosphamide
CYP2C19 protein results in increased metabolism of Cyclophosphamide
[CYP2C19 protein results in increased hydroxylation of Cyclophosphamide] which results in increased chemical synthesis of 4-hydroxycyclophosphamide; [CYP2C19 protein results in increased hydroxylation of Cyclophosphamide] which results in increased chemical synthesis of Acrolein; CYP2C19 protein polymorphism affects the activity of and affects the susceptibility to Cyclophosphamide
CYP2C19 gene polymorphism results in decreased metabolism of Cyclophosphamide
CTD PMID:9241661, PMID:15248218, PMID:16116487, PMID:20566340, PMID:30500380 NCBI chr 1:147,713,879...147,814,410
Ensembl chr 1:147,713,892...147,888,007
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 increases activity
increases expression
ISO CYP2C8 results in increased activity of Cyclophosphamide
Cyclophosphamide results in increased expression of CYP2C29 mRNA
CTD PMID:9241661, PMID:24819615 NCBI chr 1:147,236,480...147,307,988 JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 increases metabolic processing ISO CYP2D6 protein results in increased metabolism of Cyclophosphamide CTD PMID:11377097 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases metabolic processing EXP CYP2E1 results in increased metabolism of Cyclophosphamide CTD PMID:20566340 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression EXP Cyclophosphamide results in increased expression of CYP3A2 mRNA; Cyclophosphamide results in increased expression of CYP3A2 protein CTD PMID:16019949 NCBI chr12:11,641,500...11,677,818
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 affects expression
decreases expression
EXP Cyclophosphamide affects the expression of CYP3A23-3A1 mRNA
Cyclophosphamide results in decreased expression of CYP3A23-3A1 mRNA
CTD PMID:18246545 NCBI chr12:11,053,888...11,082,742
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 affects metabolic processing
increases expression
multiple interactions
affects response to substance
ISO CYP3A5 protein affects the metabolism of Cyclophosphamide
Cyclophosphamide results in increased expression of CYP3A13 mRNA
CYP3A5 gene affects the susceptibility to [Carmustine co-treated with Cyclophosphamide co-treated with Cisplatin]
CYP3A5 gene polymorphism affects the susceptibility to Cyclophosphamide
CTD PMID:16087946, PMID:24819615 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
JBrowse link
G Dcn decorin multiple interactions ISO DCN protein inhibits the reaction [TGFB1 protein results in decreased susceptibility to [Cyclophosphamide co-treated with Cisplatin co-treated with Melphalan co-treated with Thiotepa]] CTD PMID:9509296 NCBI chr 7:38,742,250...38,782,282
Ensembl chr 7:38,742,051...38,782,323
JBrowse link
G Ddb1 damage-specific DNA binding protein 1 increases expression EXP Cyclophosphamide results in increased expression of DDB1 mRNA CTD PMID:11056294 NCBI chr 1:226,657,561...226,683,356
Ensembl chr 1:226,657,561...226,683,347
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 affects expression
increases expression
multiple interactions
decreases expression
EXP
ISO
Cyclophosphamide affects the expression of DDIT3 mRNA
Cyclophosphamide results in increased expression of DDIT3 mRNA; Cyclophosphamide results in increased expression of DDIT3 protein
sacubitril-valsartan inhibits the reaction [Cyclophosphamide results in increased expression of DDIT3 mRNA]; sacubitril-valsartan inhibits the reaction [Cyclophosphamide results in increased expression of DDIT3 protein]; Valsartan inhibits the reaction [Cyclophosphamide results in increased expression of DDIT3 mRNA]; Valsartan inhibits the reaction [Cyclophosphamide results in increased expression of DDIT3 protein]
Cyclophosphamide metabolite results in decreased expression of DDIT3 mRNA
CTD PMID:18246545, PMID:24356939, PMID:32197949 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 affects response to substance ISO DDIT4 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr20:29,509,283...29,511,382
Ensembl chr20:29,509,289...29,511,382
JBrowse link
G Deaf1 DEAF1 transcription factor decreases expression EXP Cyclophosphamide results in decreased expression of DEAF1 mRNA CTD PMID:27281708 NCBI chr 1:214,283,787...214,317,466
Ensembl chr 1:214,283,790...214,317,466
JBrowse link
G Dlc1 DLC1 Rho GTPase activating protein increases expression ISO Cyclophosphamide results in increased expression of DLC1 mRNA CTD PMID:17403535 NCBI chr16:58,776,489...59,247,752
Ensembl chr16:59,077,574...59,247,754
JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 affects expression
increases expression
EXP
ISO
Cyclophosphamide affects the expression of DNAJB1 mRNA
Cyclophosphamide metabolite results in increased expression of DNAJB1 mRNA
CTD PMID:18246545, PMID:24356939 NCBI chr19:24,747,178...24,750,919
Ensembl chr19:24,747,178...24,750,919
JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 increases expression ISO Cyclophosphamide metabolite results in increased expression of DNAJB4 mRNA CTD PMID:24356939 NCBI chr 2:257,394,692...257,425,344
Ensembl chr 2:257,394,818...257,425,242
JBrowse link
G Dnajb6 DnaJ heat shock protein family (Hsp40) member B6 increases expression ISO Cyclophosphamide results in increased expression of DNAJB6 protein CTD PMID:17475930 NCBI chr 4:2,711,329...2,774,969
Ensembl chr 4:2,711,385...2,774,890
JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions
increases expression
decreases methylation
ISO Cyclophosphamide promotes the reaction [KDM1A protein results in decreased methylation of and results in decreased degradation of DNMT1 protein]
Cyclophosphamide results in increased expression of DNMT1 protein
Cyclophosphamide results in decreased methylation of DNMT1 protein
CTD PMID:22007908 NCBI chr 8:21,922,515...21,968,495
Ensembl chr 8:21,922,515...21,968,495
JBrowse link
G Dntt DNA nucleotidylexotransferase decreases expression ISO Cyclophosphamide results in decreased expression of DNTT mRNA CTD PMID:21041162 NCBI chr 1:260,289,626...260,321,174
Ensembl chr 1:260,289,589...260,321,320
JBrowse link
G Dpf3 double PHD fingers 3 decreases expression EXP Cyclophosphamide results in decreased expression of DPF3 mRNA CTD PMID:27281708 NCBI chr 6:106,660,569...106,971,310
Ensembl chr 6:106,721,349...106,971,250
JBrowse link
G Dpysl4 dihydropyrimidinase-like 4 increases expression ISO Cyclophosphamide results in increased expression of DPYSL4 mRNA CTD PMID:21527772 NCBI chr 1:211,423,022...211,438,533
Ensembl chr 1:211,423,022...211,438,531
JBrowse link
G Drd1 dopamine receptor D1 affects binding ISO Cyclophosphamide binds to DRD1 protein CTD PMID:11180191 NCBI chr17:11,099,736...11,104,352
Ensembl chr17:11,101,306...11,103,541
JBrowse link
G Drd2 dopamine receptor D2 affects binding ISO Cyclophosphamide binds to DRD2 protein CTD PMID:11180191 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Dusp10 dual specificity phosphatase 10 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of DUSP10 mRNA CTD PMID:24356939 NCBI chr13:104,284,660...104,321,455
Ensembl chr13:104,284,660...104,321,455
JBrowse link
G Dusp2 dual specificity phosphatase 2 decreases expression ISO Cyclophosphamide results in decreased expression of DUSP2 mRNA CTD PMID:21041162 NCBI chr 3:119,776,925...119,779,110
Ensembl chr 3:119,776,925...119,779,099
JBrowse link
G Dzip1 DAZ interacting zinc finger protein 1 increases expression ISO Cyclophosphamide results in increased expression of DZIP1 mRNA CTD PMID:17403535 NCBI chr15:104,117,551...104,168,574
Ensembl chr15:104,117,556...104,170,958
JBrowse link
G E2f3 E2F transcription factor 3 multiple interactions ISO E2F3 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr17:36,334,136...36,408,831
Ensembl chr17:36,334,147...36,408,831
JBrowse link
G Eda2r ectodysplasin A2 receptor increases expression ISO Cyclophosphamide results in increased expression of EDA2R mRNA CTD PMID:21527772 NCBI chr  X:66,560,200...66,602,509
Ensembl chr  X:66,561,286...66,602,506
JBrowse link
G Edn1 endothelin 1 increases expression ISO Cyclophosphamide results in increased expression of EDN1 protein CTD PMID:17562616, PMID:18548196 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Ednrb endothelin receptor type B increases expression ISO Cyclophosphamide results in increased expression of EDNRB mRNA CTD PMID:20849824 NCBI chr15:88,004,775...88,036,354
Ensembl chr15:88,006,977...88,036,354
JBrowse link
G Eef2 eukaryotic translation elongation factor 2 decreases expression EXP Cyclophosphamide results in decreased expression of EEF2 mRNA CTD PMID:18246545 NCBI chr 7:11,401,501...11,406,771
Ensembl chr 7:11,401,501...11,406,771
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO EGFR protein affects the susceptibility to [Cyclophosphamide co-treated with Doxorubicin co-treated with Fluorouracil] CTD PMID:15981280 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Egr1 early growth response 1 increases expression
multiple interactions
decreases expression
ISO
EXP
Cyclophosphamide results in increased expression of EGR1 mRNA
3-cyanoalanine inhibits the reaction [[N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Cyclophosphamide] results in increased expression of EGR1 protein]; [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Cyclophosphamide] results in increased expression of EGR1 protein
Cyclophosphamide results in increased expression of EGR1 protein
Cyclophosphamide results in decreased expression of EGR1 mRNA
CTD PMID:7498375, PMID:9776515, PMID:21041162, PMID:21527772, PMID:29129814 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Egr2 early growth response 2 decreases expression ISO Cyclophosphamide results in decreased expression of EGR2 mRNA CTD PMID:21041162 NCBI chr20:22,452,170...22,461,018
Ensembl chr20:22,454,463...22,459,025
JBrowse link
G Egr4 early growth response 4 decreases expression EXP Cyclophosphamide results in decreased expression of EGR4 mRNA CTD PMID:27281708 NCBI chr 4:117,293,620...117,296,082
Ensembl chr 4:117,293,620...117,296,082
JBrowse link
G Eif1ax eukaryotic translation initiation factor 1A, X-linked multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] affects the expression of EIF1AX mRNA CTD PMID:16322899 NCBI chr  X:37,579,959...37,595,300
Ensembl chr  X:37,579,957...37,595,486
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 increases phosphorylation
multiple interactions
EXP Cyclophosphamide results in increased phosphorylation of EIF2AK3 protein
sacubitril-valsartan inhibits the reaction [Cyclophosphamide results in increased phosphorylation of EIF2AK3 protein]; Valsartan inhibits the reaction [Cyclophosphamide results in increased phosphorylation of EIF2AK3 protein]
CTD PMID:32197949 NCBI chr 4:98,648,513...98,709,695
Ensembl chr 4:98,648,545...98,709,694
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] affects the expression of EIF4EBP1 mRNA CTD PMID:16322899 NCBI chr16:68,954,860...68,968,248
Ensembl chr16:68,954,875...68,968,248
JBrowse link
G Elovl2 ELOVL fatty acid elongase 2 affects response to substance ISO ELOVL2 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr17:21,382,461...21,422,413
Ensembl chr17:21,382,455...21,422,407
JBrowse link
G Emp1 epithelial membrane protein 1 increases expression ISO Cyclophosphamide results in increased expression of EMP1 mRNA CTD PMID:21527772 NCBI chr 4:169,161,076...169,181,967
Ensembl chr 4:169,147,243...169,181,966
JBrowse link
G Emp3 epithelial membrane protein 3 increases expression ISO Cyclophosphamide results in increased expression of EMP3 mRNA CTD PMID:21527772 NCBI chr 1:101,900,731...101,903,948
Ensembl chr 1:101,900,733...101,903,910
JBrowse link
G Epb41l2 erythrocyte membrane protein band 4.1-like 2 decreases expression ISO Cyclophosphamide results in decreased expression of EPB41L2 mRNA CTD PMID:17403535 NCBI chr 1:20,881,820...21,067,713
Ensembl chr 1:20,893,995...20,962,526
JBrowse link
G Ephx1 epoxide hydrolase 1 affects expression
increases expression
EXP Cyclophosphamide affects the expression of EPHX1 mRNA
Cyclophosphamide results in increased expression of EPHX1 mRNA
CTD PMID:18246545 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link
G Epo erythropoietin multiple interactions
increases response to substance
decreases expression
EXP angelicae sinensis extract inhibits the reaction [Cyclophosphamide results in decreased expression of EPO mRNA]; Astragali compound inhibits the reaction [Cyclophosphamide results in decreased expression of EPO mRNA]
EPO protein results in increased susceptibility to Cyclophosphamide
CTD PMID:11245434, PMID:19627214 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G Erap1 endoplasmic reticulum aminopeptidase 1 increases expression EXP Cyclophosphamide results in increased expression of ERAP1 mRNA CTD PMID:27281708 NCBI chr 2:1,410,877...1,449,734
Ensembl chr 2:1,410,934...1,449,733
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 multiple interactions ISO ERBB2 affects the susceptibility to [Doxorubicin co-treated with Cyclophosphamide co-treated with docetaxel]; ERBB2 protein affects the susceptibility to [Cyclophosphamide co-treated with Doxorubicin co-treated with docetaxel]; ERBB2 protein affects the susceptibility to [Cyclophosphamide co-treated with pirarubicin co-treated with Fluorouracil]; ERBB2 protein affects the susceptibility to [Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide]; ERBB2 protein affects the susceptibility to [Fluorouracil co-treated with Epirubicin co-treated with Cyclophosphamide]; ERBB2 protein results in decreased susceptibility to [Cyclophosphamide co-treated with Thiotepa co-treated with Carboplatin] CTD PMID:9816327, PMID:15834928, PMID:15940066, PMID:16446318, PMID:16682728, PMID:17010609 NCBI chr10:86,367,596...86,391,728
Ensembl chr10:86,367,596...86,391,728
JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 multiple interactions ISO ERBB4 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 9:75,021,790...76,178,936
Ensembl chr 9:75,021,790...75,528,644
JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit affects expression EXP Cyclophosphamide affects the expression of ERCC1 mRNA CTD PMID:11906922 NCBI chr 1:80,256,973...80,268,198
Ensembl chr 1:80,256,973...80,268,198
JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit affects expression
increases expression
multiple interactions
EXP
ISO
Cyclophosphamide affects the expression of ERCC2 mRNA
Cyclophosphamide results in increased expression of ERCC2 mRNA
5-(N-methyl-N-propargylaminomethyl)-8-hydroxyquinoline inhibits the reaction [Cyclophosphamide results in increased expression of ERCC2 mRNA]
CTD PMID:11906922, PMID:30760223 NCBI chr 1:80,293,574...80,307,334
Ensembl chr 1:80,293,566...80,307,344
JBrowse link
G Erg ETS transcription factor ERG increases expression ISO Cyclophosphamide results in increased expression of ERG mRNA CTD PMID:17403535 NCBI chr11:35,645,317...35,749,637
Ensembl chr11:35,646,116...35,749,594
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 increases phosphorylation
multiple interactions
EXP Cyclophosphamide results in increased phosphorylation of ERN1 protein
sacubitril-valsartan inhibits the reaction [Cyclophosphamide results in increased phosphorylation of ERN1 protein]; Valsartan inhibits the reaction [Cyclophosphamide results in increased phosphorylation of ERN1 protein]
CTD PMID:32197949 NCBI chr10:94,588,555...94,682,072
Ensembl chr10:94,588,555...94,681,914
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] results in increased expression of ESR1 mRNA CTD PMID:16322899 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] results in increased expression of ESR2 mRNA CTD PMID:16322899 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Esrra estrogen related receptor, alpha decreases expression
increases expression
EXP Cyclophosphamide results in decreased expression of ESRRA mRNA
Cyclophosphamide results in increased expression of ESRRA mRNA
CTD PMID:27281708 NCBI chr 1:222,168,729...222,178,842
Ensembl chr 1:222,168,730...222,178,725
JBrowse link
G Evi2a ecotropic viral integration site 2A decreases expression ISO Cyclophosphamide metabolite results in decreased expression of EVI2A mRNA CTD PMID:24356939 NCBI chr10:66,870,048...66,873,948
Ensembl chr10:66,870,067...66,873,948
JBrowse link
G F2rl1 F2R like trypsin receptor 1 increases expression EXP Cyclophosphamide results in increased expression of F2RL1 protein CTD PMID:15643279 NCBI chr 2:25,222,324...25,235,275
Ensembl chr 2:25,222,328...25,235,275
JBrowse link
G F2rl2 coagulation factor II (thrombin) receptor-like 2 increases expression EXP Cyclophosphamide results in increased expression of F2RL2 protein CTD PMID:15643279 NCBI chr 2:26,240,385...26,245,533
Ensembl chr 2:26,240,385...26,245,533
JBrowse link
G F2rl3 F2R like thrombin or trypsin receptor 3 increases expression EXP Cyclophosphamide results in increased expression of F2RL3 protein CTD PMID:15643279 NCBI chr16:18,817,797...18,819,790
Ensembl chr16:18,814,622...18,819,833
JBrowse link
G F3 coagulation factor III, tissue factor decreases expression ISO Cyclophosphamide results in decreased expression of F3 mRNA CTD PMID:17403535 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
JBrowse link
G Fam107b family with sequence similarity 107, member B decreases expression ISO Cyclophosphamide metabolite results in decreased expression of FAM107B mRNA CTD PMID:24356939 NCBI chr17:78,489,667...78,689,933
Ensembl chr17:78,489,668...78,561,613
JBrowse link
G Fam234b family with sequence similarity 234, member B multiple interactions ISO FAM234B mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 4:168,976,797...169,052,750
Ensembl chr 4:168,976,859...169,019,561
JBrowse link
G Fas Fas cell surface death receptor multiple interactions
decreases expression
increases expression
ISO
EXP
[Cyclophosphamide co-treated with cacalol] results in decreased expression of FAS protein; [Cyclophosphamide co-treated with NAc-Sar-Gly-Val-(d-allo-Ile)-Thr-Nva-Ile-Arg-ProNEt] results in increased expression of FAS
Plant Extracts inhibits the reaction [Cyclophosphamide results in increased expression of FAS mRNA]
Cyclophosphamide metabolite results in decreased expression of FAS mRNA
Cyclophosphamide results in increased expression of FAS mRNA; Cyclophosphamide results in increased expression of FAS protein
CTD PMID:10393266, PMID:16166447, PMID:20665104, PMID:24356939, PMID:25446862 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Faslg Fas ligand multiple interactions ISO [Cyclophosphamide co-treated with NAc-Sar-Gly-Val-(d-allo-Ile)-Thr-Nva-Ile-Arg-ProNEt] results in increased expression of FASLG CTD PMID:16166447 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fau FAU, ubiquitin like and ribosomal protein S30 fusion increases expression EXP Cyclophosphamide results in increased expression of FAU mRNA CTD PMID:11599041 NCBI chr 1:221,420,312...221,421,827
Ensembl chr 1:221,420,271...221,421,842
JBrowse link
G Fbxo40 F-box protein 40 increases expression EXP Cyclophosphamide results in increased expression of FBXO40 mRNA CTD PMID:27281708 NCBI chr11:66,713,913...66,731,195
Ensembl chr11:66,713,888...66,731,198
JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 increases expression ISO Cyclophosphamide results in increased expression of FBXW7 mRNA CTD PMID:29445054 NCBI chr 2:184,230,191...184,309,805
Ensembl chr 2:184,231,260...184,309,664
JBrowse link
G Fcer1g Fc fragment of IgE receptor Ig increases expression ISO Cyclophosphamide results in increased expression of FCER1G mRNA CTD PMID:21041162 NCBI chr13:89,601,894...89,606,326
Ensembl chr13:89,601,896...89,606,326
JBrowse link
G Fcgr2a Fc fragment of IgG receptor IIa increases expression ISO Cyclophosphamide results in increased expression of FCGR3 mRNA CTD PMID:21041162 NCBI chr13:91,146,878...91,163,691
Ensembl chr13:91,168,973...91,198,036
Ensembl chr13:91,168,973...91,198,036
JBrowse link
G Fcgrt Fc fragment of IgG receptor and transporter increases expression ISO Cyclophosphamide results in increased expression of FCGRT mRNA CTD PMID:21041162 NCBI chr 1:101,086,872...101,096,159
Ensembl chr 1:101,086,877...101,095,594
JBrowse link
G Fhl1 four and a half LIM domains 1 increases expression EXP Cyclophosphamide results in increased expression of FHL1 mRNA CTD PMID:23558518 NCBI chr  X:159,112,516...159,172,528
Ensembl chr  X:159,112,880...159,172,524
JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B affects response to substance ISO FKBP1B protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 6:29,975,863...29,987,252
Ensembl chr 6:29,977,797...29,987,451
JBrowse link
G Fkbpl FKBP prolyl isomerase like increases expression ISO Cyclophosphamide results in increased expression of FKBPL mRNA CTD PMID:14503796 NCBI chr20:4,411,890...4,413,360
Ensembl chr20:4,411,876...4,413,366
JBrowse link
G Flnc filamin C increases expression ISO Cyclophosphamide results in increased expression of FLNC mRNA CTD PMID:21527772 NCBI chr 4:56,710,934...56,738,779
Ensembl chr 4:56,711,049...56,738,791
JBrowse link
G Flt3lg Fms related receptor tyrosine kinase 3 ligand affects expression ISO Cyclophosphamide affects the expression of FLT3L mRNA CTD PMID:12624490 NCBI chr 1:101,126,006...101,131,413
Ensembl chr 1:101,124,479...101,131,413
JBrowse link
G Fndc3b fibronectin type III domain containing 3B affects response to substance ISO FNDC3B protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 2:113,109,949...113,415,171
Ensembl chr 2:113,112,902...113,345,577
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
ISO
EXP
Capsaicin inhibits the reaction [Cyclophosphamide results in increased expression of FOS mRNA]
Cyclophosphamide results in increased expression of FOS protein
alfuzosin inhibits the reaction [Cyclophosphamide results in increased expression of FOS protein]; Capsaicin inhibits the reaction [Cyclophosphamide results in increased expression of FOS protein]; resiniferatoxin inhibits the reaction [Cyclophosphamide results in increased expression of FOS protein]
CTD PMID:7498375, PMID:8801120, PMID:8808730, PMID:9776515, PMID:10749792, PMID:15099680, PMID:15217452, PMID:17240043, PMID:18093676 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Foxp3 forkhead box P3 decreases expression
multiple interactions
ISO Cyclophosphamide results in decreased expression of FOXP3 mRNA; Cyclophosphamide results in decreased expression of FOXP3 protein
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of FOXP3 protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of FOXP3 protein]
CTD PMID:15591121, PMID:32151603 NCBI chr  X:15,753,175...15,768,648
Ensembl chr  X:15,753,175...15,768,522
JBrowse link
G Foxp4 forkhead box P4 decreases expression EXP Cyclophosphamide results in decreased expression of FOXP4 mRNA CTD PMID:27281708 NCBI chr 9:15,068,378...15,124,962
Ensembl chr 9:15,068,399...15,125,318
JBrowse link
G Fpr2 formyl peptide receptor 2 increases expression ISO Cyclophosphamide results in increased expression of FPR2 mRNA CTD PMID:15331540 NCBI chr 1:59,800,558...59,809,507
Ensembl chr 1:59,800,984...59,802,401
JBrowse link
G Fscn1 fascin actin-bundling protein 1 increases expression ISO Cyclophosphamide results in increased expression of FSCN1 mRNA CTD PMID:17403535 NCBI chr12:13,655,459...13,668,595
Ensembl chr12:13,656,554...13,668,515
JBrowse link
G Fshb follicle stimulating hormone subunit beta increases expression
multiple interactions
decreases secretion
ISO
EXP
Cyclophosphamide results in increased expression of FSHB protein
sacubitril-valsartan inhibits the reaction [Cyclophosphamide results in decreased secretion of FSHB protein]; Valsartan inhibits the reaction [Cyclophosphamide results in decreased secretion of FSHB protein]
CTD PMID:6788612, PMID:25446862, PMID:32197949 NCBI chr 3:98,088,321...98,092,131
Ensembl chr 3:98,088,324...98,092,131
JBrowse link
G Fshr follicle stimulating hormone receptor multiple interactions
decreases expression
ISO coenzyme Q10 inhibits the reaction [Cyclophosphamide results in decreased expression of FSHR mRNA] CTD PMID:31557371 NCBI chr 6:12,796,383...12,997,817
Ensembl chr 6:12,796,383...12,997,817
JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase increases expression ISO Cyclophosphamide results in increased expression of FYN mRNA CTD PMID:17403535 NCBI chr20:44,436,354...44,630,316
Ensembl chr20:44,436,403...44,630,317
JBrowse link
G G3bp1 G3BP stress granule assembly factor 1 decreases expression ISO Cyclophosphamide results in decreased expression of G3BP1 mRNA CTD PMID:21041162 NCBI chr10:40,812,858...40,846,252
Ensembl chr10:40,812,858...40,846,252
JBrowse link
G G6pc2 glucose-6-phosphatase catalytic subunit 2 decreases expression ISO Cyclophosphamide results in decreased expression of G6PC2 mRNA CTD PMID:15331540 NCBI chr 3:55,464,528...55,467,170 JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression
affects expression
EXP
ISO
Cyclophosphamide results in increased expression of GADD45A mRNA
Cyclophosphamide affects the expression of GADD45A mRNA
CTD PMID:18246545, PMID:29445054 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Gal galanin and GMAP prepropeptide affects expression
increases expression
EXP
ISO
Cyclophosphamide affects the expression of GAL mRNA; Cyclophosphamide affects the expression of GAL protein
Cyclophosphamide results in increased expression of GAL mRNA
CTD PMID:16491427, PMID:17335920, PMID:18563302 NCBI chr 1:218,653,059...218,657,922
Ensembl chr 1:218,652,917...218,657,925
JBrowse link
G Galc galactosylceramidase affects response to substance ISO GALC protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 6:122,177,195...122,239,411
Ensembl chr 6:122,178,602...122,239,614
JBrowse link
G Gamt guanidinoacetate N-methyltransferase multiple interactions ISO GAMT mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 7:12,314,848...12,317,998
Ensembl chr 7:12,314,848...12,317,998
JBrowse link
G Gap43 growth associated protein 43 increases expression EXP Cyclophosphamide results in increased expression of GAP43 protein CTD PMID:9486479, PMID:10536274 NCBI chr11:58,624,198...58,717,916
Ensembl chr11:58,624,198...58,717,914
JBrowse link
G Gas2 growth arrest-specific 2 increases expression ISO Cyclophosphamide results in increased expression of GAS2 protein CTD PMID:17475930 NCBI chr 1:107,234,389...107,363,624
Ensembl chr 1:107,262,659...107,363,788
JBrowse link
G Gata3 GATA binding protein 3 decreases expression
multiple interactions
ISO Cyclophosphamide results in decreased expression of GATA3 mRNA; Cyclophosphamide results in decreased expression of GATA3 protein
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of GATA3 protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of GATA3 protein]
CTD PMID:21041162, PMID:32151603 NCBI chr17:72,419,752...72,452,043
Ensembl chr17:72,429,618...72,450,681
JBrowse link
G Gbp1 guanylate binding protein 1 increases expression ISO Cyclophosphamide results in increased expression of GBP1 mRNA CTD PMID:21621594 NCBI chr 2:248,343,334...248,423,402
Ensembl chr 2:248,398,917...248,409,570
JBrowse link
G Gbp2 guanylate binding protein 2 increases expression ISO Cyclophosphamide results in increased expression of GBP3 mRNA CTD PMID:15331540 NCBI chr 2:248,276,795...248,293,784
Ensembl chr 2:248,276,709...248,293,784
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions
decreases expression
ISO Cyclophosphamide promotes the reaction [NFE2L2 gene mutant form results in decreased expression of GCLC protein]
Cyclophosphamide results in decreased expression of GCLC mRNA; Cyclophosphamide results in decreased expression of GCLC protein
CTD PMID:27633142 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gdnf glial cell derived neurotrophic factor increases expression EXP Cyclophosphamide results in increased expression of GDNF mRNA CTD PMID:10683293 NCBI chr 2:56,884,181...56,912,964
Ensembl chr 2:56,887,987...56,910,238
JBrowse link
G Gem GTP binding protein overexpressed in skeletal muscle increases expression ISO Cyclophosphamide results in increased expression of GEM mRNA CTD PMID:21041162 NCBI chr 5:25,339,479...25,353,661
Ensembl chr 5:25,349,928...25,353,661
JBrowse link
G Gfi1 growth factor independent 1 transcriptional repressor decreases expression ISO Cyclophosphamide results in decreased expression of GFI1 mRNA CTD PMID:21041162 NCBI chr14:3,058,035...3,073,332
Ensembl chr14:3,058,993...3,068,371
JBrowse link
G Gfra1 GDNF family receptor alpha 1 multiple interactions ISO GFRA1 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 1:279,203,046...279,572,789 JBrowse link
G Gimap4 GTPase, IMAP family member 4 decreases expression EXP Cyclophosphamide results in decreased expression of GIMAP4 mRNA CTD PMID:27466211 NCBI chr 4:78,320,230...78,327,144
Ensembl chr 4:78,320,190...78,327,144
JBrowse link
G Gja1 gap junction protein, alpha 1 affects expression EXP Cyclophosphamide affects the expression of GJA1 mRNA CTD PMID:10859244 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Gjb1 gap junction protein, beta 1 decreases expression ISO Cyclophosphamide results in decreased expression of GJB1 mRNA CTD PMID:21621594 NCBI chr  X:71,272,030...71,279,973
Ensembl chr  X:71,272,042...71,279,977
JBrowse link
G Glis1 GLIS family zinc finger 1 decreases expression EXP Cyclophosphamide results in decreased expression of GLIS1 mRNA CTD PMID:27281708 NCBI chr 5:127,043,344...127,233,395
Ensembl chr 5:127,160,495...127,233,078
JBrowse link
G Glod4 glyoxalase domain containing 4 decreases expression ISO Cyclophosphamide results in decreased expression of GLOD4 mRNA CTD PMID:20849824 NCBI chr10:64,379,922...64,398,263
Ensembl chr10:64,379,921...64,398,294
JBrowse link
G Glrb glycine receptor, beta increases expression ISO Cyclophosphamide results in increased expression of GLRB mRNA CTD PMID:17403535 NCBI chr 2:179,768,040...179,842,612
Ensembl chr 2:179,769,009...179,842,547
JBrowse link
G Gls glutaminase increases expression
affects response to substance
ISO Cyclophosphamide results in increased expression of GLS mRNA
GLS protein affects the susceptibility to Cyclophosphamide
CTD PMID:16217747, PMID:21527772 NCBI chr 9:54,212,622...54,284,879
Ensembl chr 9:54,212,767...54,284,872
JBrowse link
G Gng12 G protein subunit gamma 12 increases expression ISO Cyclophosphamide results in increased expression of GNG12 mRNA CTD PMID:17403535 NCBI chr 4:97,634,925...97,763,478
Ensembl chr 4:97,657,671...97,760,102
JBrowse link
G Gpatch8 G patch domain containing 8 increases expression EXP Cyclophosphamide results in increased expression of GPATCH8 mRNA CTD PMID:27281708 NCBI chr10:90,421,443...90,501,996
Ensembl chr10:90,421,442...90,501,819
JBrowse link
G Gpr137b G protein-coupled receptor 137B increases expression ISO Cyclophosphamide results in increased expression of GPR137B mRNA CTD PMID:21527772 NCBI chr17:90,670,852...90,709,003
Ensembl chr17:90,670,872...90,746,804
JBrowse link
G Gpr18 G protein-coupled receptor 18 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of GPR18 mRNA CTD PMID:24356939 NCBI chr15:108,323,157...108,326,907
Ensembl chr15:108,323,179...108,326,907
JBrowse link
G Gpr20 G protein-coupled receptor 20 increases expression ISO Cyclophosphamide results in increased expression of GPR20 mRNA CTD PMID:20849824 NCBI chr 7:114,943,675...114,953,977
Ensembl chr 7:114,944,282...114,945,344
JBrowse link
G Gpt glutamic--pyruvic transaminase increases expression
increases activity
multiple interactions
EXP
ISO
Cyclophosphamide results in increased expression of GPT protein
Cyclophosphamide results in increased activity of GPT protein
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in increased activity of GPT protein]; ganoderic acid A inhibits the reaction [Cyclophosphamide results in increased activity of GPT protein]
Rutin inhibits the reaction [Cyclophosphamide results in increased activity of GPT protein]; Vitamin E inhibits the reaction [Cyclophosphamide results in increased expression of GPT protein]
CTD PMID:25753322, PMID:25779342, PMID:29753871, PMID:30506662 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Gpt2 glutamic--pyruvic transaminase 2 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of GPT2 mRNA CTD PMID:24356939 NCBI chr19:22,599,003...22,633,529
Ensembl chr19:22,590,881...22,632,071
JBrowse link
G Gpx1 glutathione peroxidase 1 decreases expression
multiple interactions
ISO Cyclophosphamide results in decreased expression of GPX1 mRNA
Plant Extracts inhibits the reaction [Cyclophosphamide results in decreased expression of GPX1 mRNA]
CTD PMID:23542512 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gpx3 glutathione peroxidase 3 increases expression ISO Cyclophosphamide results in increased expression of GPX3 mRNA CTD PMID:21041162 NCBI chr10:40,247,436...40,255,423
Ensembl chr10:40,247,436...40,255,422
JBrowse link
G Gpx4 glutathione peroxidase 4 increases expression ISO Cyclophosphamide results in increased expression of GPX4 protein CTD PMID:17475930 NCBI chr 7:12,516,357...12,519,154
Ensembl chr 7:12,516,352...12,519,154
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions
decreases activity
ISO
EXP
[[Cyclophosphamide co-treated with Cisplatin co-treated with Carmustine] results in decreased activity of GSR protein] which results in increased abundance of Glutathione Disulfide; [Cyclophosphamide co-treated with Cisplatin co-treated with Carmustine] results in decreased activity of GSR protein; Buthionine Sulfoximine promotes the reaction [Cyclophosphamide results in decreased activity of GSR protein]; Plant Extracts inhibits the reaction [Buthionine Sulfoximine promotes the reaction [Cyclophosphamide results in decreased activity of GSR protein]]; Plant Extracts inhibits the reaction [Cyclophosphamide results in decreased activity of GSR protein]
Plant Extracts inhibits the reaction [Cyclophosphamide results in decreased activity of GSR protein]; Rutin inhibits the reaction [Cyclophosphamide results in decreased activity of GSR protein]
CTD PMID:12114195, PMID:21772021, PMID:23542512, PMID:25446862, PMID:25753322 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 multiple interactions ISO GSTA1 protein affects the metabolism of [Cyclophosphamide metabolite co-treated with Glutathione] CTD PMID:12516103 NCBI chr 9:27,366,404...27,381,004
Ensembl chr 9:27,368,272...27,452,902
JBrowse link
G Gstm1 glutathione S-transferase mu 1 multiple interactions ISO [GSTM1 protein co-treated with CYP2C9 protein] results in increased susceptibility to [Busulfan co-treated with Cyclophosphamide]; GSTM1 gene affects the susceptibility to [Carmustine co-treated with Cyclophosphamide co-treated with Cisplatin] CTD PMID:16087946, PMID:28744217 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstm2 glutathione S-transferase mu 2 decreases expression EXP Cyclophosphamide results in decreased expression of GSTM2 mRNA CTD PMID:11906922 NCBI chr 2:210,778,041...210,782,807
Ensembl chr 2:210,720,704...210,782,856
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions
decreases response to substance
affects response to substance
increases expression
ISO
EXP
GSTP1 gene SNP results in increased susceptibility to [Carmustine co-treated with Doxorubicin co-treated with Cyclophosphamide co-treated with Melphalan]
GSTP1 protein results in decreased susceptibility to Cyclophosphamide
GSTP1 protein affects the susceptibility to Cyclophosphamide
GSTP1 protein affects the reaction [Cyclophosphamide results in increased phosphorylation of MAPK8 protein]; Mesna inhibits the reaction [GSTP1 protein affects the reaction [Cyclophosphamide results in increased phosphorylation of MAPK8 protein]]
Cyclophosphamide results in increased expression of GSTP1 mRNA; Cyclophosphamide results in increased expression of GSTP1 protein
CTD PMID:10954901, PMID:12791655, PMID:16141653, PMID:16242832, PMID:19696094 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Gtf2b general transcription factor IIB increases expression EXP Cyclophosphamide results in increased expression of GTF2B mRNA CTD PMID:27281708 NCBI chr 2:248,709,433...248,727,741
Ensembl chr 2:248,715,281...248,727,741
JBrowse link
G Gtf3c1 general transcription factor IIIC subunit 1 multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] affects the expression of GTF3C1 mRNA CTD PMID:16322899 NCBI chr 1:197,032,473...197,098,676
Ensembl chr 1:197,032,474...197,098,649
JBrowse link
G Gusb glucuronidase, beta decreases expression
increases activity
multiple interactions
EXP Cyclophosphamide results in decreased expression of GUSB protein
Cyclophosphamide results in increased activity of GUSB protein
Anthocyanins inhibits the reaction [Cyclophosphamide results in increased activity of GUSB protein]; Plant Extracts inhibits the reaction [Cyclophosphamide results in increased activity of GUSB protein]
CTD PMID:17686619, PMID:25451569 NCBI chr12:30,202,066...30,215,583
Ensembl chr12:30,198,822...30,227,771
JBrowse link
G Gzma granzyme A decreases expression ISO Cyclophosphamide results in decreased expression of GZMA mRNA CTD PMID:21041162 NCBI chr 2:44,968,846...44,981,436
Ensembl chr 2:44,968,765...44,981,458
JBrowse link
G Gzmb granzyme B increases expression ISO Cyclophosphamide results in increased expression of GZMB mRNA CTD PMID:15331540 NCBI chr15:35,413,862...35,417,293
Ensembl chr15:35,413,793...35,417,316
JBrowse link
G H2ax H2A.X variant histone increases phosphorylation ISO Cyclophosphamide results in increased phosphorylation of H2AX protein CTD PMID:32482060 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
JBrowse link
G Hcrt hypocretin neuropeptide precursor affects localization
decreases expression
EXP Cyclophosphamide affects the localization of HCRT protein
Cyclophosphamide results in decreased expression of HCRT mRNA
CTD PMID:17881193, PMID:19666069 NCBI chr10:88,669,216...88,670,430
Ensembl chr10:88,669,214...88,670,430
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression ISO Cyclophosphamide results in increased expression of HIF1A mRNA CTD PMID:15331540 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hinfp histone H4 transcription factor decreases expression EXP Cyclophosphamide results in decreased expression of HINFP mRNA CTD PMID:27281708 NCBI chr 8:48,626,398...48,638,012
Ensembl chr 8:48,628,340...48,634,797
JBrowse link
G Hm13 histocompatibility minor 13 decreases expression ISO Cyclophosphamide results in decreased expression of H13 mRNA CTD PMID:15331540 NCBI chr 3:148,150,695...148,189,623
Ensembl chr 3:148,150,698...148,189,623
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression ISO Cyclophosphamide metabolite results in increased expression of HMGCS1 mRNA CTD PMID:24356939 NCBI chr 2:52,427,351...52,445,082
Ensembl chr 2:52,431,601...52,445,055
JBrowse link
G Hmox1 heme oxygenase 1 affects expression
decreases expression
multiple interactions
increases expression
EXP
ISO
Cyclophosphamide affects the expression of HMOX1 mRNA
Cyclophosphamide results in decreased expression of HMOX1 protein
[astaxanthine co-treated with Cyclophosphamide] results in increased expression of HMOX1 protein; Hemin inhibits the reaction [Cyclophosphamide results in increased expression of HMOX1 mRNA]; Hemin promotes the reaction [Cyclophosphamide results in increased expression of HMOX1 mRNA]; Melatonin inhibits the reaction [Cyclophosphamide results in decreased expression of HMOX1 protein]; sacubitril-valsartan inhibits the reaction [Cyclophosphamide results in decreased expression of HMOX1 protein]; Valsartan inhibits the reaction [Cyclophosphamide results in decreased expression of HMOX1 protein]
Cyclophosphamide results in increased expression of HMOX1 mRNA; Cyclophosphamide results in increased expression of HMOX1 protein
CTD PMID:11906922, PMID:17979934, PMID:18206168, PMID:18246545, PMID:19952508, PMID:20038455, PMID:20433640, PMID:32197949 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hmox2 heme oxygenase 2 decreases expression EXP Cyclophosphamide results in decreased expression of HMOX2 mRNA CTD PMID:11906922 NCBI chr10:10,990,034...11,035,493
Ensembl chr10:10,990,034...11,035,484
JBrowse link
G Hnrnpk heterogeneous nuclear ribonucleoprotein K increases expression ISO
EXP
Cyclophosphamide results in increased expression of HNRNPK protein
Cyclophosphamide results in increased expression of HNRNPK mRNA
CTD PMID:11599041, PMID:17475930 NCBI chr17:6,664,730...6,676,753
Ensembl chr17:6,665,659...6,676,654
JBrowse link
G Hoxa1 homeobox A1 affects response to substance ISO HOXA1 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 4:82,124,358...82,127,182
Ensembl chr 4:82,125,406...82,127,066
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 increases mutagenesis ISO
EXP
Cyclophosphamide results in increased mutagenesis of HPRT1 gene CTD PMID:17116724, PMID:23677247 NCBI chr  X:158,196,640...158,228,815
Ensembl chr  X:158,197,149...158,228,749
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 decreases expression EXP Cyclophosphamide results in decreased expression of HSP90AA1 mRNA CTD PMID:11906922 NCBI chr 6:135,107,262...135,112,793
Ensembl chr 6:135,107,271...135,112,775
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 decreases expression EXP Cyclophosphamide results in decreased expression of HSP90AB1 mRNA CTD PMID:11906922 NCBI chr 9:17,817,791...17,823,163
Ensembl chr 9:17,817,721...17,823,243
JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 decreases expression
increases expression
EXP Cyclophosphamide results in decreased expression of HSP90B1 mRNA
Cyclophosphamide results in increased expression of HSP90B1 mRNA
CTD PMID:11599041, PMID:11906922 NCBI chr 7:27,226,570...27,240,533
Ensembl chr 7:27,226,569...27,240,533
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A affects expression
increases expression
EXP
ISO
Cyclophosphamide affects the expression of HSPA1A mRNA
Cyclophosphamide results in increased expression of HSPA1A mRNA; Cyclophosphamide results in increased expression of HSPA1A protein
CTD PMID:8917683, PMID:18246545 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B affects expression
increases expression
decreases expression
EXP
ISO
Cyclophosphamide affects the expression of HSPA1B mRNA
Cyclophosphamide metabolite results in increased expression of HSPA1B mRNA
Cyclophosphamide results in decreased expression of HSPA1B mRNA
CTD PMID:16141653, PMID:18246545, PMID:24356939 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 affects response to substance
increases expression
ISO
EXP
HSPA2 protein affects the susceptibility to Cyclophosphamide
Cyclophosphamide results in increased expression of HSPA2 mRNA
CTD PMID:11599041, PMID:16217747 NCBI chr 6:99,433,575...99,436,288
Ensembl chr 6:99,433,550...99,436,289
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 decreases expression
increases expression
EXP
ISO
Cyclophosphamide results in decreased expression of HSPA5 mRNA
Cyclophosphamide metabolite results in increased expression of HSPA5 mRNA
CTD PMID:11906922, PMID:24356939 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 affects response to substance ISO HSPA8 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 decreases expression EXP Cyclophosphamide results in decreased expression of HSPA9 mRNA CTD PMID:11906922 NCBI chr18:27,731,072...27,749,235
Ensembl chr18:27,731,072...27,749,235
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 decreases expression
increases expression
EXP Cyclophosphamide results in decreased expression of HSPB1 mRNA
Cyclophosphamide results in increased expression of HSPB1 mRNA
CTD PMID:11599041, PMID:11906922, PMID:18246545 NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 decreases expression EXP Cyclophosphamide results in decreased expression of HSPD1 mRNA CTD PMID:11906922 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 decreases expression EXP Cyclophosphamide results in decreased expression of HSPE1 mRNA CTD PMID:11906922 NCBI chr 9:61,691,246...61,724,948
Ensembl chr 9:61,692,154...61,694,599
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 increases expression ISO Cyclophosphamide metabolite results in increased expression of HSPH1 mRNA CTD PMID:24356939 NCBI chr12:6,322,685...6,341,898
Ensembl chr12:6,322,668...6,341,902
JBrowse link
G Hyls1 HYLS1, centriolar and ciliogenesis associated decreases expression ISO Cyclophosphamide metabolite results in decreased expression of HYLS1 mRNA CTD PMID:24356939 NCBI chr 8:36,763,470...36,772,199
Ensembl chr 8:36,763,481...36,764,422
JBrowse link
G Hyou1 hypoxia up-regulated 1 decreases expression EXP Cyclophosphamide results in decreased expression of HYOU1 mRNA CTD PMID:11906922 NCBI chr 8:48,699,796...48,711,912
Ensembl chr 8:48,699,769...48,711,910
JBrowse link
G Ica1 islet cell autoantigen 1 affects response to substance ISO ICA1 protein affects the susceptibility to Cyclophosphamide CTD PMID:11751995 NCBI chr 4:34,635,509...34,780,187
Ensembl chr 4:34,635,506...34,780,193
JBrowse link
G Icam1 intercellular adhesion molecule 1 affects response to substance ISO ICAM1 protein affects the susceptibility to Cyclophosphamide CTD PMID:11591119 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Id2 inhibitor of DNA binding 2 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of ID2 mRNA CTD PMID:24356939 NCBI chr 6:44,360,077...44,361,908
Ensembl chr 6:44,348,501...44,363,915
JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 increases expression ISO Cyclophosphamide metabolite results in increased expression of IDI1 mRNA CTD PMID:24356939 NCBI chr17:57,976,266...57,984,036
Ensembl chr17:57,976,268...57,984,036
JBrowse link
G Ier3 immediate early response 3 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of IER3 mRNA CTD PMID:24356939 NCBI chr20:3,438,798...3,440,002
Ensembl chr20:3,438,798...3,440,769
JBrowse link
G Ier5 immediate early response 5 increases expression ISO Cyclophosphamide results in increased expression of IER5 mRNA CTD PMID:21527772 NCBI chr13:72,742,210...72,744,302
Ensembl chr13:72,742,210...72,744,303
JBrowse link
G Ifit2 interferon-induced protein with tetratricopeptide repeats 2 increases expression ISO Cyclophosphamide results in increased expression of IFIT2 mRNA CTD PMID:15331540 NCBI chr 1:252,894,663...252,900,727
Ensembl chr 1:252,894,663...252,900,726
JBrowse link
G Ifng interferon gamma affects expression
multiple interactions
decreases secretion
increases expression
decreases expression
ISO
EXP
Cyclophosphamide affects the expression of IFNG mRNA
[Cyclophosphamide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA
Cyclophosphamide results in decreased secretion of IFNG protein
Cyclophosphamide results in increased expression of IFNG mRNA
Cyclophosphamide results in decreased expression of IFNG mRNA
Cyclophosphamide results in increased expression of IFNG protein
(4-formyl-9-methoxy-5-methyl-naphtho(2,3-b)furan-3-yl)methyl acetate inhibits the reaction [Cyclophosphamide results in decreased secretion of IFNG protein]; Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of IFNG mRNA]; IFNG protein inhibits the reaction [Cyclophosphamide results in increased abundance of Nitric Oxide]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of IFNG mRNA]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased secretion of IFNG protein]
CTD PMID:10607705, PMID:11006010, PMID:11014644, PMID:15331540, PMID:18848347, PMID:18957084, PMID:21068404, PMID:22842586, PMID:23395935, PMID:29594315, PMID:32151603 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Ifngr1 interferon gamma receptor 1 decreases expression ISO Cyclophosphamide results in decreased expression of IFNGR1 mRNA CTD PMID:21041162 NCBI chr 1:15,062,380...15,080,815
Ensembl chr 1:15,062,432...15,080,907
JBrowse link
G Ifrd1 interferon-related developmental regulator 1 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of IFRD1 mRNA CTD PMID:24356939 NCBI chr 6:60,132,025...60,151,354
Ensembl chr 6:60,132,024...60,151,420
JBrowse link
G Igf2bp3 insulin-like growth factor 2 mRNA binding protein 3 affects response to substance ISO IGF2BP3 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 4:78,744,683...78,879,457
Ensembl chr 4:78,746,547...78,879,294
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 affects response to substance
decreases expression
ISO
EXP
IGFBP3 protein affects the susceptibility to Cyclophosphamide
Cyclophosphamide results in decreased expression of IGFBP3 mRNA
CTD PMID:16141653, PMID:16217747 NCBI chr14:87,457,647...87,465,374
Ensembl chr14:87,457,647...87,465,374
JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 multiple interactions ISO IGFBP4 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr10:86,950,555...86,962,563
Ensembl chr10:86,950,557...86,962,578
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 decreases expression ISO Cyclophosphamide results in decreased expression of IGFBP5 mRNA CTD PMID:15331540, PMID:20849824 NCBI chr 9:80,154,230...80,166,813
Ensembl chr 9:80,150,211...80,167,033
JBrowse link
G Igkc immunoglobulin kappa constant decreases expression ISO Cyclophosphamide results in decreased expression of IGKC mRNA CTD PMID:15331540
G Il10 interleukin 10 decreases expression
multiple interactions
increases expression
ISO
EXP
Cyclophosphamide results in decreased expression of IL10 mRNA
[Cyclophosphamide co-treated with Methotrexate co-treated with Fluorouracil] results in decreased expression of IL10 protein
Anthocyanins inhibits the reaction [Cyclophosphamide results in decreased expression of IL10 protein]; Plant Extracts inhibits the reaction [Cyclophosphamide results in decreased expression of IL10 protein]
Cyclophosphamide results in increased expression of IL10 mRNA
Cyclophosphamide results in increased expression of IL10 protein
CTD PMID:11014644, PMID:11948286, PMID:18848347, PMID:21068404, PMID:25451569, PMID:31651976 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il12a interleukin 12A multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] results in decreased expression of [IL12A protein binds to IL12B protein] CTD PMID:29228376 NCBI chr 2:165,076,945...165,083,996
Ensembl chr 2:165,076,607...165,084,318
JBrowse link
G Il12b interleukin 12B affects expression
multiple interactions
increases expression
ISO Cyclophosphamide affects the expression of IL12B mRNA
[Doxorubicin co-treated with Cyclophosphamide] results in decreased expression of [IL12A protein binds to IL12B protein]
Cyclophosphamide results in increased expression of IL12B mRNA
CTD PMID:15331540, PMID:18957084, PMID:22842586, PMID:29228376 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
JBrowse link
G Il13ra1 interleukin 13 receptor subunit alpha 1 increases expression ISO Cyclophosphamide results in increased expression of IL13RA1 mRNA CTD PMID:21041162 NCBI chr  X:122,724,081...122,783,801
Ensembl chr  X:122,724,129...122,781,479
JBrowse link
G Il15 interleukin 15 multiple interactions
decreases secretion
ISO (4-formyl-9-methoxy-5-methyl-naphtho(2,3-b)furan-3-yl)methyl acetate inhibits the reaction [Cyclophosphamide results in decreased secretion of IL15 protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased secretion of IL15 protein] CTD PMID:23395935 NCBI chr19:23,542,606...23,624,366
Ensembl chr19:23,542,889...23,554,594
JBrowse link
G Il15ra interleukin 15 receptor subunit alpha increases expression ISO Cyclophosphamide results in increased expression of IL15RA mRNA CTD PMID:21041162 NCBI chr17:70,451,861...70,481,838
Ensembl chr17:70,451,411...70,481,750
JBrowse link
G Il16 interleukin 16 decreases expression ISO Cyclophosphamide results in decreased expression of IL16 mRNA CTD PMID:21041162 NCBI chr 1:145,781,923...145,881,538
Ensembl chr 1:145,781,928...145,870,912
JBrowse link
G Il17a interleukin 17A decreases expression
multiple interactions
ISO Cyclophosphamide results in decreased expression of IL17A protein
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of IL17A protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of IL17A protein]
CTD PMID:21880982, PMID:32151603 NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786
JBrowse link
G Il18 interleukin 18 increases expression EXP Cyclophosphamide results in increased expression of IL18 protein CTD PMID:18848347 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il1a interleukin 1 alpha increases expression
multiple interactions
affects response to substance
ISO
EXP
Cyclophosphamide results in increased expression of IL1A mRNA
[Cyclophosphamide co-treated with Methotrexate co-treated with Fluorouracil] results in decreased expression of IL1A protein
Cyclophosphamide results in increased expression of IL1A protein
IL1A promoter polymorphism affects the susceptibility to Cyclophosphamide
CTD PMID:15331540, PMID:16636934, PMID:18848347, PMID:31651976 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta increases expression
decreases expression
increases response to substance
multiple interactions
ISO
EXP
Cyclophosphamide results in increased expression of IL1B mRNA; Cyclophosphamide results in increased expression of IL1B protein
Cyclophosphamide results in decreased expression of IL1B protein
IL1B protein results in increased susceptibility to Cyclophosphamide
[Cyclophosphamide co-treated with Methotrexate co-treated with Fluorouracil] results in decreased expression of IL1B protein; [Doxorubicin co-treated with Cyclophosphamide] results in decreased expression of IL1B protein; Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of IL1B protein]; Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]; ganoderic acid A inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of IL1B protein]; VIP protein inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]
Anthocyanins inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]; Bilirubin inhibits the reaction [Cyclophosphamide results in increased expression of IL1B mRNA]; Pentoxifylline inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]; Plant Extracts inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]; Rolipram inhibits the reaction [Cyclophosphamide results in increased expression of IL1B mRNA]; Simvastatin inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]
CTD PMID:8634684, PMID:11948286, PMID:15331540, PMID:18206168, PMID:18483878, PMID:18710439, PMID:18848347, PMID:20126887, PMID:23695977, PMID:25451569, PMID:29228376, PMID:29753871, PMID:30506662, PMID:31651976, PMID:32151603 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1rn interleukin 1 receptor antagonist increases expression ISO Cyclophosphamide results in increased expression of IL1RN mRNA CTD PMID:15331540 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
JBrowse link
G Il2 interleukin 2 increases expression
decreases expression
decreases secretion
multiple interactions
ISO
EXP
Cyclophosphamide results in increased expression of IL2 mRNA
Cyclophosphamide results in decreased expression of IL2 mRNA
Cyclophosphamide results in decreased secretion of IL2 protein
(4-formyl-9-methoxy-5-methyl-naphtho(2,3-b)furan-3-yl)methyl acetate inhibits the reaction [Cyclophosphamide results in decreased secretion of IL2 protein]; Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of IL2 mRNA]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of IL2 mRNA]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased secretion of IL2 protein]
Cyclophosphamide results in decreased expression of IL2 protein
CTD PMID:11006010, PMID:11948286, PMID:18848347, PMID:23395935, PMID:32151603 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il21 interleukin 21 multiple interactions
decreases expression
ISO Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of IL21 protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of IL21 protein] CTD PMID:32151603 NCBI chr 2:123,965,021...123,972,356
Ensembl chr 2:123,965,021...123,972,356
JBrowse link
G Il23a interleukin 23 subunit alpha decreases secretion
decreases expression
multiple interactions
ISO Cyclophosphamide results in decreased secretion of IL23A protein
Cyclophosphamide results in decreased expression of IL23A protein
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of IL23A protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of IL23A protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased secretion of IL23A protein]
CTD PMID:23395935, PMID:32151603 NCBI chr 7:2,710,609...2,712,723
Ensembl chr 7:2,710,609...2,712,723
JBrowse link
G Il3 interleukin 3 multiple interactions ISO [Cyclophosphamide co-treated with Methotrexate co-treated with Fluorouracil] results in decreased expression of IL3 protein CTD PMID:31651976 NCBI chr10:39,620,535...39,622,973
Ensembl chr10:39,620,563...39,622,973
JBrowse link
G Il4 interleukin 4 decreases expression
multiple interactions
increases expression
ISO
EXP
Cyclophosphamide results in decreased expression of IL4 mRNA; Cyclophosphamide results in decreased expression of IL4 protein
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of IL4 protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of IL4 protein]
Cyclophosphamide results in increased expression of IL4 mRNA; Cyclophosphamide results in increased expression of IL4 protein
CTD PMID:11006010, PMID:11014644, PMID:11948286, PMID:18848347, PMID:22842586, PMID:32151603 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il5 interleukin 5 increases expression ISO
EXP
Cyclophosphamide results in increased expression of IL5 mRNA; Cyclophosphamide results in increased expression of IL5 protein CTD PMID:11006010, PMID:18848347 NCBI chr10:39,066,716...39,069,587
Ensembl chr10:39,066,716...39,069,587
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
decreases secretion
ISO
EXP
[Doxorubicin co-treated with Cyclophosphamide] results in decreased expression of IL6 protein; ganoderic acid A inhibits the reaction [Cyclophosphamide results in increased expression of IL6 protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased secretion of IL6 protein]; Sizofiran promotes the reaction [Cyclophosphamide results in increased expression of IL6 mRNA]; Sizofiran promotes the reaction [Cyclophosphamide results in increased expression of IL6 protein]
Cyclophosphamide results in increased expression of IL6 mRNA; Cyclophosphamide results in increased expression of IL6 protein
Pentoxifylline inhibits the reaction [Cyclophosphamide results in increased expression of IL6 protein]; Rutin inhibits the reaction [Cyclophosphamide results in increased expression of IL6 protein]; Simvastatin inhibits the reaction [Cyclophosphamide results in increased expression of IL6 protein]
CTD PMID:10052129, PMID:11948286, PMID:17010015, PMID:18848347, PMID:20126887, PMID:21068404, PMID:22842586, PMID:23395935, PMID:23695977, PMID:25753322, PMID:29228376, PMID:30506662 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Ilf3 interleukin enhancer binding factor 3 multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] affects the expression of ILF3 mRNA CTD PMID:16322899 NCBI chr 8:22,402,877...22,440,984
Ensembl chr 8:22,402,890...22,440,885
JBrowse link
G Irag2 inositol 1,4,5-triphosphate receptor associated 2 decreases expression ISO Cyclophosphamide results in decreased expression of LRMP mRNA CTD PMID:21041162 NCBI chr 4:179,402,929...179,440,792
Ensembl chr 4:179,398,621...179,440,792
JBrowse link
G Irs1 insulin receptor substrate 1 multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] affects the expression of IRS1 mRNA CTD PMID:16322899 NCBI chr 9:88,033,668...88,086,488
Ensembl chr 9:88,033,668...88,086,488
JBrowse link
G Isg15 ISG15 ubiquitin-like modifier increases expression ISO Cyclophosphamide results in increased expression of ISG15 mRNA CTD PMID:21527772 NCBI chr 5:173,624,862...173,629,124
Ensembl chr 5:173,624,310...173,626,248
JBrowse link
G Isl2 ISL LIM homeobox 2 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of ISL2 mRNA CTD PMID:24356939 NCBI chr 8:60,117,565...60,122,716
Ensembl chr 8:60,117,729...60,122,211
JBrowse link
G Itk IL2-inducible T-cell kinase decreases expression ISO Cyclophosphamide results in decreased expression of ITK mRNA CTD PMID:21041162 NCBI chr10:31,431,820...31,493,413
Ensembl chr10:31,431,809...31,493,419
JBrowse link
G Jchain joining chain of multimeric IgA and IgM decreases expression ISO Cyclophosphamide results in decreased expression of JCHAIN mRNA CTD PMID:15331540 NCBI chr14:21,176,841...21,183,731
Ensembl chr14:21,177,237...21,183,542
JBrowse link
G Kbtbd11 kelch repeat and BTB domain containing 11 decreases expression ISO Cyclophosphamide results in decreased expression of KBTBD11 mRNA CTD PMID:17403535 NCBI chr16:79,696,395...79,716,129
Ensembl chr16:79,696,891...79,700,992
JBrowse link
G Kcnq4 potassium voltage-gated channel subfamily Q member 4 decreases expression ISO Cyclophosphamide results in decreased expression of KCNQ4 mRNA CTD PMID:20849824 NCBI chr 5:139,625,783...139,677,300
Ensembl chr 5:139,627,576...139,677,300
JBrowse link
G Kdm1a lysine demethylase 1A multiple interactions
increases expression
ISO Cyclophosphamide promotes the reaction [KDM1A protein results in decreased methylation of and results in decreased degradation of DNMT1 protein]
Cyclophosphamide results in increased expression of KDM1A protein
CTD PMID:22007908 NCBI chr 5:154,909,003...154,965,171
Ensembl chr 5:154,909,003...154,965,171
JBrowse link
G Kdm2a lysine demethylase 2A increases expression EXP Cyclophosphamide results in increased expression of KDM2A mRNA CTD PMID:27281708 NCBI chr 1:219,566,130...219,642,294
Ensembl chr 1:219,566,156...219,640,294
JBrowse link
G Kdm4b lysine demethylase 4B multiple interactions ISO KDM4B mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 9:10,656,035...10,734,127
Ensembl chr 9:10,653,216...10,734,073
JBrowse link
G Kdr kinase insert domain receptor decreases expression
increases expression
EXP Cyclophosphamide results in decreased expression of KDR mRNA; Cyclophosphamide results in decreased expression of KDR protein
Cyclophosphamide results in increased expression of KDR mRNA
CTD PMID:18632792, PMID:19701751 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183
JBrowse link
G Kif21b kinesin family member 21B decreases expression ISO Cyclophosphamide metabolite results in decreased expression of KIF21B mRNA CTD PMID:24356939 NCBI chr13:52,976,505...53,026,750
Ensembl chr13:52,976,507...53,023,103
JBrowse link
G Kif3a kinesin family member 3a multiple interactions ISO KIF3A mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr10:38,918,705...38,953,958
Ensembl chr10:38,918,748...38,952,785
JBrowse link
G Kitlg KIT ligand affects expression
increases expression
multiple interactions
ISO Cyclophosphamide affects the expression of KITL mRNA
Cyclophosphamide results in increased expression of KITL mRNA
[Cyclophosphamide co-treated with Sizofiran] results in increased expression of KITL mRNA
CTD PMID:10052129, PMID:12624490, PMID:12662436 NCBI chr 7:42,269,784...42,351,054
Ensembl chr 7:42,269,784...42,351,054
JBrowse link
G Klf13 Kruppel-like factor 13 decreases expression ISO Cyclophosphamide results in decreased expression of KLF13 mRNA CTD PMID:21041162 NCBI chr 1:124,772,596...124,803,363
Ensembl chr 1:124,772,596...124,803,363
JBrowse link
G Klf2 Kruppel-like factor 2 increases expression ISO Cyclophosphamide results in increased expression of KLF2 mRNA CTD PMID:21041162 NCBI chr16:19,223,087...19,225,037
Ensembl chr16:19,223,087...19,225,037
JBrowse link
G Klf4 Kruppel like factor 4 decreases response to substance ISO KLF4 results in decreased susceptibility to Cyclophosphamide CTD PMID:21833590 NCBI chr 5:72,283,311...72,287,669
Ensembl chr 5:72,283,313...72,287,669
JBrowse link
G Klf5 Kruppel-like factor 5 affects response to substance ISO KLF5 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr15:83,703,796...83,722,921
Ensembl chr15:83,703,791...83,722,921
JBrowse link
G Krcc1 lysine-rich coiled-coil 1 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of KRCC1 mRNA CTD PMID:24356939 NCBI chr 4:99,133,735...99,148,236
Ensembl chr 4:99,133,842...99,146,827
JBrowse link
G Krt8 keratin 8 decreases expression ISO Cyclophosphamide results in decreased expression of KRT8 mRNA CTD PMID:21621594 NCBI chr 7:143,596,511...143,603,745
Ensembl chr 7:143,596,511...143,603,803
JBrowse link
G Krt80 keratin 80 increases expression ISO Cyclophosphamide results in increased expression of KRT80 mRNA CTD PMID:21527772 NCBI chr 7:142,995,715...143,015,932
Ensembl chr 7:142,994,119...143,016,040
JBrowse link
G Lama5 laminin subunit alpha 5 increases expression
multiple interactions
ISO Cyclophosphamide results in increased expression of LAMA5 mRNA
5-(N-methyl-N-propargylaminomethyl)-8-hydroxyquinoline inhibits the reaction [Cyclophosphamide results in increased expression of LAMA5 mRNA]
CTD PMID:30760223 NCBI chr 3:175,553,042...175,601,112
Ensembl chr 3:175,553,045...175,601,127
JBrowse link
G Lamc2 laminin subunit gamma 2 increases expression ISO Cyclophosphamide results in increased expression of LAMC2 mRNA CTD PMID:21527772 NCBI chr13:70,566,643...70,632,126
Ensembl chr13:70,566,643...70,626,252
JBrowse link
G Lasp1 LIM and SH3 protein 1 decreases expression EXP Cyclophosphamide results in decreased expression of LASP1 mRNA CTD PMID:27281708 NCBI chr10:85,744,662...85,785,130
Ensembl chr10:85,744,568...85,785,133
JBrowse link
G Lat linker for activation of T cells decreases expression ISO Cyclophosphamide results in decreased expression of LAT mRNA CTD PMID:21041162 NCBI chr 1:197,765,644...197,770,669
Ensembl chr 1:197,765,644...197,770,669
JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase decreases expression ISO Cyclophosphamide results in decreased expression of LCK mRNA CTD PMID:21041162 NCBI chr 5:147,750,976...147,779,627
Ensembl chr 5:147,750,973...147,761,983
JBrowse link
G Lcn2 lipocalin 2 increases expression
multiple interactions
ISO
EXP
Cyclophosphamide results in increased expression of LCN2 mRNA
[Cyclophosphamide co-treated with Mecamylamine] results in increased expression of LCN2 mRNA
CTD PMID:15331540, PMID:18433785, PMID:20623750 NCBI chr 3:11,414,189...11,417,534
Ensembl chr 3:11,414,186...11,417,546
JBrowse link
G Ldhb lactate dehydrogenase B affects response to substance ISO LDHB protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 4:176,701,980...176,719,999
Ensembl chr 4:176,701,983...176,720,012
JBrowse link
G Lef1 lymphoid enhancer binding factor 1 decreases expression ISO Cyclophosphamide results in decreased expression of LEF1 mRNA CTD PMID:21041162 NCBI chr 2:236,232,115...236,345,061
Ensembl chr 2:236,233,239...236,345,056
JBrowse link
G Lgals1 galectin 1 increases expression ISO Cyclophosphamide results in increased expression of LGALS1 mRNA CTD PMID:17403535 NCBI chr 7:120,153,184...120,156,290
Ensembl chr 7:120,153,184...120,156,289
JBrowse link
G Lgals7 galectin 7 increases expression ISO Cyclophosphamide results in increased expression of LGALS7 mRNA CTD PMID:21527772 NCBI chr 1:87,044,823...87,047,223
Ensembl chr 1:87,045,335...87,047,223
JBrowse link
G Lhb luteinizing hormone subunit beta decreases secretion
multiple interactions
EXP Cyclophosphamide results in decreased secretion of LHB protein
sacubitril-valsartan inhibits the reaction [Cyclophosphamide results in decreased secretion of LHB protein]; Valsartan inhibits the reaction [Cyclophosphamide results in decreased secretion of LHB protein]
CTD PMID:25446862, PMID:32197949 NCBI chr 1:101,409,992...101,413,725
Ensembl chr 1:101,410,019...101,413,724
JBrowse link
G Lhx2 LIM homeobox 2 decreases expression EXP Cyclophosphamide results in decreased expression of LHX2 mRNA CTD PMID:27281708 NCBI chr 3:22,628,674...22,658,447
Ensembl chr 3:22,640,545...22,658,446
JBrowse link
G Limd1 LIM domains containing 1 increases expression EXP Cyclophosphamide results in increased expression of LIMD1 mRNA CTD PMID:27281708 NCBI chr 8:132,553,218...132,598,826
Ensembl chr 8:132,553,218...132,598,812
JBrowse link
G Lmcd1 LIM and cysteine-rich domains 1 increases expression EXP Cyclophosphamide results in increased expression of LMCD1 mRNA CTD PMID:23558518 NCBI chr 4:144,192,989...144,252,554
Ensembl chr 4:144,192,989...144,252,551
JBrowse link
G Lmnb1 lamin B1 multiple interactions ISO [Cladribine co-treated with Cyclophosphamide co-treated with Mitoxantrone] results in decreased expression of LMNB1 protein; [Cladribine co-treated with Cyclophosphamide] results in decreased expression of LMNB1 protein CTD PMID:15582267 NCBI chr18:51,785,111...51,822,264
Ensembl chr18:51,785,111...51,822,264
JBrowse link
G Lonrf2 LON peptidase N-terminal domain and ring finger 2 increases expression EXP Cyclophosphamide results in increased expression of LONRF2 mRNA CTD PMID:27281708 NCBI chr 9:45,468,001...45,506,448
Ensembl chr 9:45,466,688...45,505,767
JBrowse link
G Lsg1 large 60S subunit nuclear export GTPase 1 decreases expression ISO Cyclophosphamide results in decreased expression of LSG1 mRNA CTD PMID:20849824 NCBI chr11:73,693,862...73,723,457
Ensembl chr11:73,693,814...73,723,501
JBrowse link
G Ltbr lymphotoxin beta receptor increases expression ISO Cyclophosphamide results in increased expression of LTBR mRNA CTD PMID:21041162 NCBI chr 4:157,822,838...157,829,291
Ensembl chr 4:157,822,840...157,829,241
JBrowse link
G Ltf lactotransferrin decreases expression ISO Cyclophosphamide results in decreased expression of LTF mRNA CTD PMID:21621594 NCBI chr 8:119,290,416...119,313,261
Ensembl chr 8:119,290,416...119,313,261
JBrowse link
G Maged1 MAGE family member D1 affects response to substance ISO MAGED1 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr  X:63,803,194...63,809,715
Ensembl chr  X:63,803,189...63,809,861
JBrowse link
G Man2b2 mannosidase, alpha, class 2B, member 2 decreases expression EXP Cyclophosphamide results in decreased expression of MAN2B2 mRNA CTD PMID:27281708 NCBI chr14:78,939,959...78,964,961
Ensembl chr14:78,939,903...78,964,961
JBrowse link
G Maoa monoamine oxidase A increases expression ISO Cyclophosphamide results in increased expression of MAOA mRNA CTD PMID:17403535 NCBI chr  X:6,554,698...6,620,722
Ensembl chr  X:6,554,698...6,620,722
JBrowse link
G Map3k12 mitogen activated protein kinase kinase kinase 12 affects expression EXP Cyclophosphamide affects the expression of MAP3K12 mRNA CTD PMID:18246545 NCBI chr 7:144,102,275...144,120,306
Ensembl chr 7:144,102,680...144,109,116
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions
increases expression
ISO
EXP
Cyclophosphamide results in increased phosphorylation of MAPK1 protein
Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK1 protein; NGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]
Cyclophosphamide results in increased expression of MAPK1 mRNA; Cyclophosphamide results in increased expression of MAPK1 protein modified form
CTD PMID:11599041, PMID:15733095, PMID:17110531, PMID:17409261, PMID:19638304, PMID:19696094, PMID:19996110 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions
decreases expression
affects expression
ISO
EXP
[Doxorubicin co-treated with Cyclophosphamide] affects the expression of MAPK14 mRNA
Cyclophosphamide results in decreased expression of MAPK14 mRNA
Cyclophosphamide affects the expression of MAPK14 mRNA
CTD PMID:16322899, PMID:18246545 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases expression
multiple interactions
increases phosphorylation
EXP
ISO
Cyclophosphamide results in increased expression of MAPK3 protein modified form
Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK3 protein; NGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]
Cyclophosphamide results in increased phosphorylation of MAPK3 protein
CTD PMID:15733095, PMID:17110531, PMID:17409261, PMID:19638304, PMID:19696094, PMID:19996110 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk7 mitogen-activated protein kinase 7 multiple interactions EXP Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK7 protein CTD PMID:17110531 NCBI chr10:47,768,592...47,775,130
Ensembl chr10:47,766,680...47,775,055
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation
multiple interactions
ISO
EXP
Cyclophosphamide results in increased phosphorylation of MAPK8 protein
Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK8 protein; NGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK8 protein]
GSTP1 protein affects the reaction [Cyclophosphamide results in increased phosphorylation of MAPK8 protein]; GSTP2 protein affects the reaction [Cyclophosphamide results in increased phosphorylation of MAPK8 protein]; Mesna inhibits the reaction [Cyclophosphamide results in increased phosphorylation of MAPK8 protein]; Mesna inhibits the reaction [GSTP1 protein affects the reaction [Cyclophosphamide results in increased phosphorylation of MAPK8 protein]]; Mesna inhibits the reaction [GSTP2 protein affects the reaction [Cyclophosphamide results in increased phosphorylation of MAPK8 protein]]
CTD PMID:19696094, PMID:19996110 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions EXP Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK9 protein; NGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK9 protein] CTD PMID:19996110 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Mapt microtubule-associated protein tau multiple interactions ISO MAPT mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr10:92,289,002...92,386,517
Ensembl chr10:92,288,910...92,386,517
JBrowse link
G Marchf7 membrane associated ring-CH-type finger 7 decreases expression EXP Cyclophosphamide results in decreased expression of MARCHF7 mRNA CTD PMID:27281708 NCBI chr 3:46,284,961...46,325,230
Ensembl chr 3:46,286,712...46,324,057
JBrowse link
G Marcks myristoylated alanine rich protein kinase C substrate increases expression ISO Cyclophosphamide results in increased expression of MARCKS mRNA CTD PMID:17403535 NCBI chr20:42,966,140...42,971,838
Ensembl chr20:42,966,140...42,971,838
JBrowse link
G Mcm5 minichromosome maintenance complex component 5 decreases expression ISO Cyclophosphamide results in decreased expression of MCM5 mRNA CTD PMID:21041162 NCBI chr19:14,523,482...14,561,281
Ensembl chr19:14,523,554...14,561,278
JBrowse link
G Mdfic MyoD family inhibitor domain containing decreases expression ISO Cyclophosphamide results in decreased expression of MDFIC mRNA CTD PMID:17403535 NCBI chr 4:42,202,546...42,282,499
Ensembl chr 4:42,202,838...42,282,496
JBrowse link
G Med13l mediator complex subunit 13L multiple interactions ISO MED13L mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr12:43,421,317...43,576,859
Ensembl chr12:43,421,308...43,576,804
JBrowse link
G Melk maternal embryonic leucine zipper kinase multiple interactions ISO MELK mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 5:59,783,835...59,844,356
Ensembl chr 5:59,783,890...59,844,356
JBrowse link
G Metrn meteorin, glial cell differentiation regulator multiple interactions ISO METRN mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr10:15,164,439...15,166,457
Ensembl chr10:15,164,439...15,166,457
JBrowse link
G Mfge8 milk fat globule EGF and factor V/VIII domain containing decreases expression ISO Cyclophosphamide results in decreased expression of MFGE8 mRNA CTD PMID:15331540 NCBI chr 1:140,845,478...140,860,882
Ensembl chr 1:140,845,465...140,860,894
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase decreases expression
decreases response to substance
ISO Cyclophosphamide results in decreased expression of MGMT mRNA
MGMT protein results in decreased susceptibility to Cyclophosphamide
CTD PMID:15741301, PMID:17403535 NCBI chr 1:209,237,255...209,464,189
Ensembl chr 1:209,237,233...209,464,190
JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 decreases expression EXP Cyclophosphamide results in decreased expression of MGST1 mRNA CTD PMID:11906922 NCBI chr 4:172,119,382...172,134,609
Ensembl chr 4:172,119,331...172,134,607
JBrowse link
G Mif macrophage migration inhibitory factor multiple interactions EXP Cyclophosphamide affects the localization of and affects the expression of MIF protein; Cyclophosphamide promotes the reaction [MIF protein binds to CXCR4 protein] CTD PMID:19066630 NCBI chr20:13,715,219...13,732,980
Ensembl chr20:13,732,198...13,732,859
JBrowse link
G Mlh1 mutL homolog 1 decreases expression EXP Cyclophosphamide results in decreased expression of MLH1 mRNA CTD PMID:11906922 NCBI chr 8:119,486,655...119,523,716
Ensembl chr 8:119,486,691...119,523,964
JBrowse link
G Mmel1 membrane metallo-endopeptidase-like 1 increases expression EXP Cyclophosphamide results in increased expression of MMEL1 mRNA CTD PMID:27281708 NCBI chr 5:172,273,450...172,303,905
Ensembl chr 5:172,273,459...172,304,225
JBrowse link
G Mmp11 matrix metallopeptidase 11 decreases expression EXP Cyclophosphamide results in decreased expression of MMP11 mRNA CTD PMID:27281708 NCBI chr20:13,670,051...13,678,834
Ensembl chr20:13,670,066...13,678,089
JBrowse link
G Mmp3 matrix metallopeptidase 3 increases expression ISO Cyclophosphamide results in increased expression of MMP3 mRNA CTD PMID:15331540 NCBI chr 8:5,676,608...5,698,579
Ensembl chr 8:5,676,665...5,698,579
JBrowse link
G Mmp8 matrix metallopeptidase 8 increases expression EXP Cyclophosphamide results in increased expression of MMP8 mRNA CTD PMID:27281708 NCBI chr 8:5,768,808...5,777,741
Ensembl chr 8:5,768,811...5,778,702
JBrowse link
G Mnda myeloid cell nuclear differentiation antigen increases expression ISO Cyclophosphamide results in increased expression of IFI204 mRNA CTD PMID:21041162 NCBI chr13:92,073,664...92,091,335
Ensembl chr13:92,073,668...92,089,980
JBrowse link
G Mpc2 mitochondrial pyruvate carrier 2 affects response to substance ISO MPC2 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr13:83,680,527...83,700,491
Ensembl chr13:83,681,322...83,700,213
JBrowse link
G Mpg N-methylpurine-DNA glycosylase affects expression EXP Cyclophosphamide affects the expression of MPG mRNA CTD PMID:11906922 NCBI chr10:15,661,768...15,667,995
Ensembl chr10:15,661,608...15,668,022
JBrowse link
G Mpo myeloperoxidase multiple interactions
increases activity
EXP Anthocyanins inhibits the reaction [Cyclophosphamide results in increased activity of MPO protein]; Hemin inhibits the reaction [Cyclophosphamide results in increased activity of MPO protein]; Plant Extracts inhibits the reaction [Cyclophosphamide results in increased activity of MPO protein]; Rolipram inhibits the reaction [Cyclophosphamide results in increased activity of MPO protein] CTD PMID:10749792, PMID:17979934, PMID:18710439, PMID:25451569 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Mr1 major histocompatibility complex, class I-related increases expression ISO Cyclophosphamide results in increased expression of MR1 mRNA CTD PMID:21527772 NCBI chr13:72,771,992...72,789,861
Ensembl chr13:72,771,984...72,789,841
JBrowse link
G Ms4a3 membrane spanning 4-domains A3 decreases expression ISO Cyclophosphamide results in decreased expression of MS4A3 mRNA CTD PMID:17403535 NCBI chr 1:227,979,307...227,994,210
Ensembl chr 1:227,979,481...227,992,623
JBrowse link
G Msh2 mutS homolog 2 decreases expression EXP Cyclophosphamide results in decreased expression of MSH2 mRNA CTD PMID:11056294, PMID:11906922 NCBI chr 6:11,215,951...11,274,916
Ensembl chr 6:11,215,963...11,274,932
JBrowse link
G Msh3 mutS homolog 3 decreases expression EXP Cyclophosphamide results in decreased expression of MSH3 mRNA CTD PMID:11906922 NCBI chr 2:21,790,048...21,931,791
Ensembl chr 2:21,790,044...21,931,720
JBrowse link
G Mss51 MSS51 mitochondrial translational activator increases expression EXP Cyclophosphamide results in increased expression of MSS51 mRNA CTD PMID:27281708 NCBI chr15:4,240,203...4,252,072
Ensembl chr15:4,240,203...4,252,072
JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase decreases expression ISO Cyclophosphamide metabolite results in decreased expression of MTHFD2 mRNA CTD PMID:24356939 NCBI chr 4:115,004,433...115,015,965
Ensembl chr 4:115,004,448...115,015,965
JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase decreases expression EXP Cyclophosphamide results in decreased expression of MTR mRNA CTD PMID:27281708 NCBI chr17:66,210,444...66,295,014
Ensembl chr17:66,210,461...66,295,014
JBrowse link
G Muc13 mucin 13, cell surface associated increases expression ISO Cyclophosphamide results in increased expression of MUC13 mRNA CTD PMID:15331540 NCBI chr11:70,185,757...70,223,012
Ensembl chr11:70,185,757...70,211,701
JBrowse link
G Mxi1 MAX interactor 1, dimerization protein affects response to substance ISO MXI1 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 1:274,030,748...274,090,071
Ensembl chr 1:274,030,978...274,090,071
JBrowse link
G Myh10 myosin heavy chain 10 affects response to substance ISO MYH10 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr10:55,274,910...55,406,738
Ensembl chr10:55,275,411...55,406,732
JBrowse link
G Naip6 NLR family, apoptosis inhibitory protein 6 multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] affects the expression of NAIP mRNA CTD PMID:16322899 NCBI chr 2:30,377,505...30,418,578 JBrowse link
G Nampt nicotinamide phosphoribosyltransferase increases expression ISO Cyclophosphamide results in increased expression of NAMPT mRNA CTD PMID:21041162 NCBI chr 6:52,122,085...52,156,473
Ensembl chr 6:52,122,085...52,156,472
JBrowse link
G Nanos1 nanos C2HC-type zinc finger 1 increases expression ISO Cyclophosphamide metabolite results in increased expression of NANOS1 mRNA CTD PMID:24356939 NCBI chr 1:282,134,676...282,140,370
Ensembl chr 1:282,134,981...282,135,772
JBrowse link
G Nasp nuclear autoantigenic sperm protein increases expression EXP Cyclophosphamide results in increased expression of NASP mRNA CTD PMID:16141653 NCBI chr 5:135,446,485...135,472,113
Ensembl chr 5:135,446,962...135,472,116
JBrowse link
G Ncoa7 nuclear receptor coactivator 7 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of NCOA7 mRNA CTD PMID:24356939 NCBI chr 1:29,225,727...29,386,642
Ensembl chr 1:29,225,707...29,385,199
JBrowse link
G Ndufs2 NADH:ubiquinone oxidoreductase core subunit S2 decreases expression ISO Cyclophosphamide results in decreased expression of NDUFS2 mRNA CTD PMID:15331540 NCBI chr13:89,606,848...89,623,506
Ensembl chr13:89,606,840...89,619,398
JBrowse link
G Neto2 neuropilin and tolloid like 2 increases expression ISO Cyclophosphamide results in increased expression of NETO2 mRNA CTD PMID:21527772 NCBI chr19:22,450,579...22,486,530
Ensembl chr19:22,450,030...22,486,531
JBrowse link
G Nfatc3 nuclear factor of activated T-cells 3 decreases expression ISO Cyclophosphamide results in decreased expression of NFATC3 mRNA CTD PMID:21041162 NCBI chr19:38,039,542...38,114,003
Ensembl chr19:38,039,564...38,114,003
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions
increases response to substance
increases expression
decreases expression
EXP
ISO
[astaxanthine co-treated with Cyclophosphamide] results in increased expression of NFE2L2 protein; Melatonin inhibits the reaction [Cyclophosphamide results in decreased expression of NFE2L2 protein]
Cyclophosphamide promotes the reaction [NFE2L2 gene mutant form results in decreased expression of CAT protein]; Cyclophosphamide promotes the reaction [NFE2L2 gene mutant form results in decreased expression of GCLC protein]; Cyclophosphamide promotes the reaction [NFE2L2 gene mutant form results in decreased expression of NQO1 protein]; NFE2L2 gene mutant form inhibits the reaction [Cyclophosphamide results in increased expression of NQO1 mRNA]; NFE2L2 gene mutant form promotes the reaction [Cyclophosphamide results in decreased expression of CAT protein]; NFE2L2 gene mutant form promotes the reaction [Cyclophosphamide results in decreased expression of NQO1 protein]
NFE2L2 gene mutant form results in increased susceptibility to Cyclophosphamide
Cyclophosphamide results in increased expression of NFE2L2 protein
CTD PMID:20038455, PMID:20433640, PMID:27633142 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfe2l3 nuclear factor, erythroid 2-like 3 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of NFE2L3 mRNA CTD PMID:24356939 NCBI chr 4:81,205,214...81,233,068
Ensembl chr 4:81,205,404...81,232,813
JBrowse link
G Nfkbia NFKB inhibitor alpha increases phosphorylation
multiple interactions
ISO Cyclophosphamide results in increased phosphorylation of NFKBIA protein
ganoderic acid A inhibits the reaction [Cyclophosphamide results in increased phosphorylation of NFKBIA protein]
CTD PMID:30506662 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nfkbiz NFKB inhibitor zeta increases expression ISO Cyclophosphamide results in increased expression of NFKBIZ mRNA CTD PMID:15331540 NCBI chr11:47,243,342...47,271,487
Ensembl chr11:47,243,342...47,271,487
JBrowse link
G Ngf nerve growth factor multiple interactions
increases expression
decreases expression
ISO
EXP
3-(4-hydroxyphenyl)-4,5-dihydro-5-isoxazoleacetic acid methyl ester inhibits the reaction [Cyclophosphamide results in increased expression of NGF protein]; Cyclophosphamide promotes the reaction [NGF results in increased expression of VEGFA mRNA]; VIP protein affects the reaction [Cyclophosphamide results in increased expression of NGF protein]
Cyclophosphamide results in decreased expression of NGF protein
Cyclophosphamide results in increased expression of NGF mRNA; Cyclophosphamide results in increased expression of NGF protein
NGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of AKT1 protein]; NGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; NGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; NGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK8 protein]; NGF protein affects the reaction [Cyclophosphamide results in increased phosphorylation of and results in increased activity of MAPK9 protein]; rofecoxib inhibits the reaction [Cyclophosphamide results in increased expression of NGF protein]
CTD PMID:10683293, PMID:16879691, PMID:18299998, PMID:18632792, PMID:19996110, PMID:20127836 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453
JBrowse link
G Ngfr nerve growth factor receptor increases expression EXP Cyclophosphamide results in increased expression of NGFR mRNA; Cyclophosphamide results in increased expression of NGFR protein CTD PMID:8817519, PMID:18189308, PMID:18842820 NCBI chr10:83,389,828...83,408,061
Ensembl chr10:83,389,847...83,408,061
JBrowse link
G Nid1 nidogen 1 affects response to substance ISO NID1 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr17:90,553,161...90,627,133
Ensembl chr17:90,553,394...90,627,101
JBrowse link
G Nkain1 Sodium/potassium transporting ATPase interacting 1 multiple interactions ISO NKAIN1 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 5:148,635,537...148,669,709
Ensembl chr 5:148,661,070...148,667,746
JBrowse link
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 increases expression EXP Cyclophosphamide results in increased expression of NME1 mRNA CTD PMID:11599041 NCBI chr10:81,657,152...81,666,542
Ensembl chr10:81,657,153...81,666,523
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
increases expression
increases activity
EXP
ISO
Bilirubin inhibits the reaction [Cyclophosphamide results in increased expression of NOS2 mRNA]; Bilirubin inhibits the reaction [Cyclophosphamide results in increased expression of NOS2 protein]; ginkgolide B inhibits the reaction [Cyclophosphamide results in increased activity of NOS2 protein]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [Cyclophosphamide results in increased activity of NOS2 protein]; pimagedine inhibits the reaction [Cyclophosphamide results in increased activity of NOS2 protein]; rofecoxib inhibits the reaction [Cyclophosphamide results in increased expression of NOS2 protein]; Rolipram inhibits the reaction [Cyclophosphamide results in increased expression of NOS2 mRNA]; Rolipram inhibits the reaction [Cyclophosphamide results in increased expression of NOS2 protein]; Rutin inhibits the reaction [Cyclophosphamide results in increased expression of NOS2 protein]; sacubitril-valsartan inhibits the reaction [Cyclophosphamide results in increased expression of NOS2 protein]; Valsartan inhibits the reaction [Cyclophosphamide results in increased expression of NOS2 protein]
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in increased expression of NOS2 protein]
Cyclophosphamide results in increased expression of NOS2 mRNA; Cyclophosphamide results in increased expression of NOS2 protein
CTD PMID:9006340, PMID:10607705, PMID:11046124, PMID:15821589, PMID:16879691, PMID:18206168, PMID:18296739, PMID:18710439, PMID:19691848, PMID:21068404, PMID:25753322, PMID:29753871, PMID:32197949 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nos3 nitric oxide synthase 3 decreases activity
increases expression
EXP Cyclophosphamide results in decreased activity of NOS3 protein
Cyclophosphamide results in increased expression of NOS3 protein
CTD PMID:9006340, PMID:16125470 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Nppb natriuretic peptide B increases expression ISO Cyclophosphamide results in increased expression of NPPB protein CTD PMID:17562616, PMID:18548196, PMID:18999883 NCBI chr 5:164,796,176...164,797,538
Ensembl chr 5:164,796,185...164,797,531
JBrowse link
G Nprl2 NPR2-like, GATOR1 complex subunit decreases expression ISO Cyclophosphamide results in decreased expression of NPRL2 mRNA CTD PMID:20849824 NCBI chr 8:116,297,950...116,301,123
Ensembl chr 8:116,297,950...116,301,122
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 decreases expression
multiple interactions
increases expression
EXP
ISO
Cyclophosphamide results in decreased expression of NQO1 mRNA; Cyclophosphamide results in decreased expression of NQO1 protein
Cyclophosphamide promotes the reaction [NFE2L2 gene mutant form results in decreased expression of NQO1 protein]; NFE2L2 gene mutant form inhibits the reaction [Cyclophosphamide results in increased expression of NQO1 mRNA]; NFE2L2 gene mutant form promotes the reaction [Cyclophosphamide results in decreased expression of NQO1 protein]
Cyclophosphamide results in increased expression of NQO1 protein
[astaxanthine co-treated with Cyclophosphamide] results in increased expression of NQO1 protein; Melatonin inhibits the reaction [Cyclophosphamide results in decreased expression of NQO1 protein]; sacubitril-valsartan inhibits the reaction [Cyclophosphamide results in decreased expression of NQO1 protein]; Valsartan inhibits the reaction [Cyclophosphamide results in decreased expression of NQO1 protein]
CTD PMID:11906922, PMID:20038455, PMID:20433640, PMID:21041162, PMID:27633142, PMID:32197949 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 decreases expression EXP Cyclophosphamide results in decreased expression of NR1H4 mRNA CTD PMID:28391356 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity
multiple interactions
ISO Cyclophosphamide results in increased activity of NR1I2 protein
[Cyclophosphamide results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA; [Cyclophosphamide results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; Cyclophosphamide binds to and results in increased activity of NR1I2 protein; NR1I2 protein promotes the reaction [Cyclophosphamide results in increased expression of ABCB1 protein]
CTD PMID:17041008, PMID:18839173, PMID:20041327 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions ISO [Cyclophosphamide results in increased activity of NR1I3 protein alternative form] which results in increased expression of CYP2B6 mRNA CTD PMID:17041008 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Nr2c2 nuclear receptor subfamily 2, group C, member 2 increases expression EXP Cyclophosphamide results in increased expression of NR2C2 mRNA CTD PMID:27281708 NCBI chr 4:124,005,287...124,030,349
Ensembl chr 4:124,005,280...124,030,349
JBrowse link
G Nrap nebulin-related anchoring protein increases expression EXP Cyclophosphamide results in increased expression of NRAP mRNA CTD PMID:27281708 NCBI chr 1:277,104,519...277,181,397
Ensembl chr 1:277,104,514...277,181,414
JBrowse link
G Nrdc nardilysin convertase decreases expression EXP Cyclophosphamide results in decreased expression of NRD1 mRNA CTD PMID:27281708 NCBI chr 5:128,629,949...128,694,209
Ensembl chr 5:128,629,942...128,694,060
JBrowse link
G Nrg1 neuregulin 1 increases expression ISO Cyclophosphamide results in increased expression of NRG1 mRNA CTD PMID:21527772 NCBI chr16:62,969,573...64,065,063
Ensembl chr16:63,837,216...64,057,434
JBrowse link
G Nrp1 neuropilin 1 decreases expression
increases expression
ISO
EXP
Cyclophosphamide results in decreased expression of NRP1 mRNA
Cyclophosphamide results in increased expression of NRP1 mRNA
CTD PMID:15331540, PMID:18632792 NCBI chr19:61,332,351...61,486,166
Ensembl chr19:61,332,351...61,485,858
JBrowse link
G Nrp2 neuropilin 2 increases expression EXP Cyclophosphamide results in increased expression of NRP2 mRNA CTD PMID:18632792 NCBI chr 9:69,496,875...69,609,802
Ensembl chr 9:69,497,121...69,612,087
JBrowse link
G Nt5c2 5'-nucleotidase, cytosolic II increases expression ISO Cyclophosphamide results in increased expression of NT5C2 mRNA CTD PMID:20849824 NCBI chr 1:266,652,966...266,782,935
Ensembl chr 1:266,659,519...266,782,910
JBrowse link
G Ntf3 neurotrophin 3 increases expression EXP Cyclophosphamide results in increased expression of NTF3 mRNA CTD PMID:10683293 NCBI chr 4:158,636,883...158,705,886
Ensembl chr 4:158,636,884...158,705,886
JBrowse link
G Ntf4 neurotrophin 4 increases expression EXP Cyclophosphamide results in increased expression of NTF4 mRNA CTD PMID:10683293 NCBI chr 1:101,405,314...101,408,145
Ensembl chr 1:101,405,314...101,408,145
JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 multiple interactions EXP Cyclophosphamide results in increased phosphorylation of and results in increased expression of NTRK1 protein CTD PMID:12412144 NCBI chr 2:187,143,568...187,160,373
Ensembl chr 2:187,143,568...187,160,373
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 multiple interactions EXP Cyclophosphamide results in increased phosphorylation of and results in increased expression of NTRK2 protein CTD PMID:12412144 NCBI chr17:5,934,651...6,245,778
Ensembl chr17:5,933,729...6,244,676
JBrowse link
G Nupl2 nucleoporin like 2 increases expression EXP Cyclophosphamide results in increased expression of NUPL2 mRNA CTD PMID:27281708 NCBI chr 4:7,512,326...7,529,106
Ensembl chr 4:7,512,326...7,529,106
JBrowse link
G Ocln occludin decreases expression
multiple interactions
ISO Cyclophosphamide results in decreased expression of OCLN protein
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of OCLN protein]
CTD PMID:32151603 NCBI chr 2:30,527,327...30,577,218
Ensembl chr 2:30,527,715...30,577,218
JBrowse link
G Odc1 ornithine decarboxylase 1 increases expression EXP Cyclophosphamide results in increased expression of ODC1 mRNA CTD PMID:11599041 NCBI chr 6:42,852,529...42,859,142
Ensembl chr 6:42,852,683...42,859,927
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase decreases expression ISO Cyclophosphamide results in decreased expression of OGG1 protein CTD PMID:27032448 NCBI chr 4:145,282,828...145,289,367
Ensembl chr 4:145,282,797...145,289,326
JBrowse link
G Opn3 opsin 3 affects response to substance ISO OPN3 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr13:93,716,481...93,746,994
Ensembl chr13:93,716,481...93,746,994
JBrowse link
G Osm oncostatin M affects expression ISO Cyclophosphamide affects the expression of OSM mRNA CTD PMID:12624490 NCBI chr14:84,457,487...84,469,426
Ensembl chr14:84,465,515...84,470,409
JBrowse link
G P2rx3 purinergic receptor P2X 3 increases expression
multiple interactions
EXP Cyclophosphamide results in increased expression of P2RX3 protein
GR 82334 inhibits the reaction [Cyclophosphamide results in increased expression of P2RX3 protein]; Suramin inhibits the reaction [Cyclophosphamide results in increased expression of P2RX3 protein]
CTD PMID:23666265 NCBI chr 3:72,403,992...72,447,801
Ensembl chr 3:72,403,993...72,447,801
JBrowse link
G P2ry2 purinergic receptor P2Y2 decreases expression ISO Cyclophosphamide results in decreased expression of P2RY2 mRNA CTD PMID:17403535 NCBI chr 1:166,031,228...166,045,423
Ensembl chr 1:166,031,272...166,037,424
JBrowse link
G Paip1 poly(A) binding protein interacting protein 1 decreases expression ISO Cyclophosphamide results in decreased expression of PAIP1 mRNA CTD PMID:20849824 NCBI chr 2:52,300,921...52,328,212
Ensembl chr 2:52,301,798...52,328,205
JBrowse link
G Pard3 par-3 family cell polarity regulator decreases expression ISO Cyclophosphamide results in decreased expression of PARD3 mRNA CTD PMID:20849824 NCBI chr19:60,017,746...60,580,628
Ensembl chr19:60,017,746...60,580,651
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases expression
increases cleavage
decreases expression
ISO
EXP
[Cladribine co-treated with Cyclophosphamide co-treated with Mitoxantrone] results in decreased expression of PARP1 protein; [Cladribine co-treated with Cyclophosphamide] results in decreased expression of PARP1 protein
Cyclophosphamide results in increased expression of PARP1 mRNA
Cyclophosphamide results in increased cleavage of PARP1 protein
Cyclophosphamide results in decreased expression of PARP1 mRNA
CTD PMID:11599041, PMID:11723234, PMID:11906922, PMID:15582267, PMID:17898787 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pcna proliferating cell nuclear antigen affects expression
multiple interactions
decreases expression
increases expression
EXP
ISO
Cyclophosphamide affects the expression of PCNA mRNA
coenzyme Q10 inhibits the reaction [Cyclophosphamide results in decreased expression of PCNA mRNA]
Cyclophosphamide results in decreased expression of PCNA protein
Cyclophosphamide results in increased expression of PCNA mRNA
CTD PMID:11056294, PMID:18246545, PMID:19701751, PMID:21041162, PMID:31557371 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Pcsk2 proprotein convertase subtilisin/kexin type 2 decreases expression ISO Cyclophosphamide results in decreased expression of PCSK2 mRNA CTD PMID:15331540 NCBI chr 3:137,618,891...137,923,385
Ensembl chr 3:137,618,898...137,925,605
JBrowse link
G Pdcd4 programmed cell death 4 decreases expression ISO Cyclophosphamide results in decreased expression of PDCD4 mRNA CTD PMID:21873647 NCBI chr 1:274,616,625...274,648,204
Ensembl chr 1:274,625,224...274,648,204
JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 decreases expression EXP Cyclophosphamide results in decreased expression of PDIA3 mRNA CTD PMID:11906922 NCBI chr 3:113,376,983...113,400,707
Ensembl chr 3:113,376,983...113,400,707
JBrowse link
G Pdia4 protein disulfide isomerase family A, member 4 increases expression EXP Cyclophosphamide results in increased expression of PDIA4 mRNA CTD PMID:11599041 NCBI chr 4:77,470,636...77,489,535
Ensembl chr 4:77,470,636...77,489,535
JBrowse link
G Peli1 pellino E3 ubiquitin protein ligase 1 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of PELI1 mRNA CTD PMID:24356939 NCBI chr14:106,008,086...106,062,566
Ensembl chr14:106,008,086...106,061,641
JBrowse link
G Per1 period circadian regulator 1 multiple interactions
decreases expression
ISO 5-(N-methyl-N-propargylaminomethyl)-8-hydroxyquinoline inhibits the reaction [Cyclophosphamide results in decreased expression of PER1 mRNA] CTD PMID:30760223 NCBI chr10:55,681,761...55,696,557
Ensembl chr10:55,687,050...55,695,994
JBrowse link
G Phlda2 pleckstrin homology-like domain, family A, member 2 increases expression ISO Cyclophosphamide results in increased expression of PHLDA2 mRNA CTD PMID:17403535 NCBI chr 1:216,701,345...216,704,479
Ensembl chr 1:216,702,319...216,703,534
JBrowse link
G Piga phosphatidylinositol glycan anchor biosynthesis, class A increases mutagenesis EXP Cyclophosphamide results in increased mutagenesis of PIGA CTD PMID:22923490 NCBI chr  X:31,786,823...31,799,751
Ensembl chr  X:31,786,194...31,799,560
JBrowse link
G Pigr polymeric immunoglobulin receptor increases expression ISO Cyclophosphamide results in increased expression of PIGR mRNA CTD PMID:15331540 NCBI chr13:47,564,176...47,592,093
Ensembl chr13:47,572,219...47,591,699
JBrowse link
G Pla2g4a phospholipase A2 group IVA increases expression ISO Cyclophosphamide results in increased expression of PLA2G4A mRNA CTD PMID:21041162 NCBI chr13:67,062,252...67,206,688
Ensembl chr13:66,988,937...67,206,693
JBrowse link
G Plau plasminogen activator, urokinase increases expression ISO Cyclophosphamide results in increased expression of PLAU mRNA CTD PMID:21527772 NCBI chr15:3,644,296...3,650,765
Ensembl chr15:3,644,769...3,650,819
JBrowse link
G Plod1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] affects the expression of PLOD1 mRNA CTD PMID:16322899 NCBI chr 5:164,720,629...164,747,071
Ensembl chr 5:164,720,587...164,747,083
JBrowse link
G Plod3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] affects the expression of PLOD3 mRNA CTD PMID:16322899 NCBI chr12:22,716,421...22,726,982
Ensembl chr12:22,716,423...22,726,982
JBrowse link
G Pms1 PMS1 homolog 1, mismatch repair system component increases expression EXP Cyclophosphamide results in increased expression of PMS1 mRNA CTD PMID:11056294 NCBI chr 9:53,120,656...53,206,520
Ensembl chr 9:53,120,656...53,206,516
JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component decreases expression EXP Cyclophosphamide results in decreased expression of PMS2 mRNA CTD PMID:11056294 NCBI chr12:12,714,394...12,738,654
Ensembl chr12:12,714,394...12,738,641
JBrowse link
G Polm DNA polymerase mu increases expression ISO Cyclophosphamide results in increased expression of POLM mRNA CTD PMID:20849824 NCBI chr14:86,069,378...86,079,327
Ensembl chr14:86,069,016...86,078,954
JBrowse link
G Pomc proopiomelanocortin increases expression EXP Cyclophosphamide results in increased expression of POMC protein CTD PMID:15276878 NCBI chr 6:28,382,937...28,388,771
Ensembl chr 6:28,382,962...28,388,967
JBrowse link
G Pon1 paraoxonase 1 increases activity EXP Cyclophosphamide results in increased activity of PON1 protein CTD PMID:17874068 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
G Por cytochrome p450 oxidoreductase multiple interactions
increases expression
ISO
EXP
POR promotes the reaction [CYP2B6 results in increased susceptibility to Cyclophosphamide]; POR promotes the reaction [CYP2C18 results in increased susceptibility to Cyclophosphamide]; POR protein promotes the reaction [CYP2B6 protein results in increased susceptibility to Cyclophosphamide]
Cyclophosphamide results in increased expression of POR mRNA
CTD PMID:9766669, PMID:10919648, PMID:11599041 NCBI chr12:23,998,411...24,017,063
Ensembl chr12:23,998,411...24,046,814
JBrowse link
G Postn periostin decreases expression ISO Cyclophosphamide results in decreased expression of POSTN mRNA CTD PMID:15331540 NCBI chr 2:143,656,820...143,688,087
Ensembl chr 2:143,656,793...143,688,087
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha decreases expression
multiple interactions
ISO Cyclophosphamide results in decreased expression of PPARA protein
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of PPARA protein]
CTD PMID:29753871 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases expression
increases expression
multiple interactions
EXP Cyclophosphamide results in decreased expression of PPARG mRNA
Cyclophosphamide results in increased expression of PPARG mRNA
Plant Extracts inhibits the reaction [Cyclophosphamide results in decreased expression of PPARG mRNA]
CTD PMID:25446862, PMID:27281708 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Prdm13 PR/SET domain 13 affects expression EXP Cyclophosphamide affects the expression of PRDM13 mRNA CTD PMID:27281708 NCBI chr 5:35,821,023...35,831,897
Ensembl chr 5:35,823,983...35,831,712
JBrowse link
G Prkcg protein kinase C, gamma decreases expression EXP Cyclophosphamide results in decreased expression of PRKCG mRNA CTD PMID:27281708 NCBI chr 1:64,407,098...64,433,698
Ensembl chr 1:64,407,114...64,433,636
JBrowse link
G Prlr prolactin receptor decreases expression ISO Cyclophosphamide results in decreased expression of PRLR mRNA CTD PMID:15331540 NCBI chr 2:60,131,410...60,325,686
Ensembl chr 2:60,131,776...60,325,692
JBrowse link
G Procr protein C receptor increases expression ISO Cyclophosphamide results in increased expression of PROCR mRNA CTD PMID:21527772 NCBI chr 3:151,285,321...151,289,581
Ensembl chr 3:151,285,249...151,289,595
JBrowse link
G Prss3 serine protease 3 affects response to substance ISO PRSS3 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 4:70,614,524...70,617,998
Ensembl chr 4:70,614,524...70,617,998
JBrowse link
G Prtn3 proteinase 3 decreases expression ISO Cyclophosphamide results in decreased expression of PRTN3 mRNA CTD PMID:17403535 NCBI chr 7:12,643,712...12,646,951
Ensembl chr 7:12,643,516...12,646,960
JBrowse link
G Psma5 proteasome 20S subunit alpha 5 increases expression ISO Cyclophosphamide results in increased expression of PSMA5 protein CTD PMID:17475930 NCBI chr 2:211,050,344...211,073,706
Ensembl chr 2:211,050,360...211,073,714
JBrowse link
G Ptcra pre T-cell antigen receptor alpha decreases expression ISO Cyclophosphamide results in decreased expression of PTCRA mRNA CTD PMID:21041162 NCBI chr 9:16,528,970...16,539,383
Ensembl chr 9:16,529,579...16,539,472
JBrowse link
G Ptger1 prostaglandin E receptor 1 decreases expression EXP Cyclophosphamide results in decreased expression of PTGER1 protein CTD PMID:20346049 NCBI chr19:24,799,422...24,803,373
Ensembl chr19:24,800,072...24,803,373
JBrowse link
G Ptger4 prostaglandin E receptor 4 multiple interactions
increases expression
EXP Botulinum Toxins, Type A inhibits the reaction [Cyclophosphamide results in increased expression of PTGER4 protein] CTD PMID:18514386, PMID:20346049 NCBI chr 2:54,951,625...54,966,470
Ensembl chr 2:54,952,821...54,963,448
JBrowse link
G Ptges3 prostaglandin E synthase 3 increases expression EXP Cyclophosphamide results in increased expression of PTGES3 mRNA CTD PMID:11599041 NCBI chr 7:2,479,267...2,497,024
Ensembl chr 7:2,479,311...2,497,013
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 increases expression ISO Cyclophosphamide results in increased expression of PTGS1 mRNA CTD PMID:21041162 NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 affects response to substance
multiple interactions
increases expression
ISO
EXP
PTGS2 protein affects the susceptibility to Cyclophosphamide
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in increased expression of PTGS2 protein]
Cyclophosphamide results in increased expression of PTGS2 mRNA; Cyclophosphamide results in increased expression of PTGS2 protein
Botulinum Toxins, Type A inhibits the reaction [Cyclophosphamide results in increased expression of PTGS2 protein]; parthenolide inhibits the reaction [Cyclophosphamide results in increased expression of PTGS2 protein]; Rutin inhibits the reaction [Cyclophosphamide results in increased expression of PTGS2 protein]
CTD PMID:12388444, PMID:15331540, PMID:16217747, PMID:17537839, PMID:18514386, PMID:19303104, PMID:25753322, PMID:29753871 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ptp4a1 protein tyrosine phosphatase 4A1 increases expression ISO Cyclophosphamide results in increased expression of PTP4A1 mRNA CTD PMID:15331540 NCBI chr 9:37,223,363...37,254,222
Ensembl chr 9:37,223,729...37,231,291
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C decreases expression ISO Cyclophosphamide results in decreased expression of PTPRC mRNA CTD PMID:21041162 NCBI chr13:55,061,561...55,174,150
Ensembl chr13:55,061,562...55,173,692
JBrowse link
G Pura purine rich element binding protein A increases expression EXP Cyclophosphamide results in increased expression of PURA mRNA CTD PMID:11599041 NCBI chr18:29,104,712...29,114,918
Ensembl chr18:29,110,242...29,111,156
JBrowse link
G Rad50 RAD50 double strand break repair protein increases expression EXP Cyclophosphamide results in increased expression of RAD50 mRNA CTD PMID:11056294 NCBI chr10:39,002,130...39,054,042
Ensembl chr10:39,001,498...39,054,142
JBrowse link
G Rad51 RAD51 recombinase decreases expression
increases expression
ISO
EXP
Cyclophosphamide results in decreased expression of RAD51 mRNA
Cyclophosphamide results in increased expression of RAD51 mRNA
CTD PMID:11599041, PMID:21041162 NCBI chr 3:110,918,240...110,942,920
Ensembl chr 3:110,918,243...110,942,917
JBrowse link
G Rad54l RAD54 like decreases expression EXP Cyclophosphamide results in decreased expression of RAD54L mRNA CTD PMID:11056294 NCBI chr 5:134,948,511...134,978,125
Ensembl chr 5:134,948,512...134,978,125
JBrowse link
G Rag1 recombination activating 1 decreases expression ISO Cyclophosphamide results in decreased expression of RAG1 mRNA CTD PMID:21041162 NCBI chr 3:91,206,394...91,217,491
Ensembl chr 3:91,206,394...91,217,491
JBrowse link
G Ramp1 receptor activity modifying protein 1 increases expression
multiple interactions
ISO Cyclophosphamide results in increased expression of RAMP1 mRNA
RAMP1 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide]
CTD PMID:16896004, PMID:17403535 NCBI chr 9:98,313,632...98,364,206
Ensembl chr 9:98,313,632...98,364,205
JBrowse link
G Rapsn receptor-associated protein of the synapse increases expression EXP Cyclophosphamide results in increased expression of RAPSN mRNA CTD PMID:27281708 NCBI chr 3:79,859,815...79,869,486
Ensembl chr 3:79,860,179...79,869,524
JBrowse link
G Rara retinoic acid receptor, alpha increases expression EXP Cyclophosphamide results in increased expression of RARA mRNA CTD PMID:16141653 NCBI chr10:86,838,819...86,884,224
Ensembl chr10:86,860,685...86,884,210
JBrowse link
G Rarg retinoic acid receptor, gamma decreases expression EXP Cyclophosphamide results in decreased expression of RARG mRNA CTD PMID:27281708 NCBI chr 7:143,840,739...143,863,206
Ensembl chr 7:143,839,980...143,863,186
JBrowse link
G Rbpms RNA binding protein, mRNA processing factor increases expression ISO Cyclophosphamide results in increased expression of RBPMS mRNA CTD PMID:17403535 NCBI chr16:61,954,569...62,109,998
Ensembl chr16:61,954,590...62,096,497
JBrowse link
G Rc3h1 ring finger and CCCH-type domains 1 decreases expression EXP Cyclophosphamide results in decreased expression of RC3H1 mRNA CTD PMID:27281708 NCBI chr13:78,723,028...78,794,663
Ensembl chr13:78,722,763...78,789,266
JBrowse link
G Rc3h2 ring finger and CCCH-type domains 2 decreases expression EXP Cyclophosphamide results in decreased expression of RC3H2 mRNA CTD PMID:27281708 NCBI chr 3:21,621,976...21,676,789
Ensembl chr 3:21,623,041...21,670,014
JBrowse link
G Reg3b regenerating family member 3 beta increases expression ISO
EXP
Cyclophosphamide results in increased expression of REG3A mRNA; Cyclophosphamide results in increased expression of REG3B mRNA
Cyclophosphamide results in increased expression of REG3B protein
CTD PMID:15331540, PMID:18295254 NCBI chr 4:109,467,272...109,470,510
Ensembl chr 4:109,467,272...109,470,510
JBrowse link
G Reg3g regenerating family member 3 gamma increases expression ISO
EXP
Cyclophosphamide results in increased expression of REG3G mRNA
Cyclophosphamide results in increased expression of REG3G protein
CTD PMID:15331540, PMID:18295254 NCBI chr 4:109,529,679...109,532,234
Ensembl chr 4:109,529,679...109,532,234
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases expression
increases phosphorylation
increases activity
multiple interactions
EXP
ISO
Cyclophosphamide results in increased expression of RELA protein; Cyclophosphamide results in increased expression of RELA protein modified form
Cyclophosphamide results in increased phosphorylation of RELA protein
Cyclophosphamide results in increased activity of RELA protein
Cyclophosphamide results in increased localization of and results in increased activity of RELA protein; Dexamethasone inhibits the reaction [Cyclophosphamide results in increased localization of and results in increased activity of RELA protein]; ganoderic acid A inhibits the reaction [Cyclophosphamide results in increased phosphorylation of RELA protein]
Anthocyanins inhibits the reaction [Cyclophosphamide results in increased activity of RELA protein]; Melatonin inhibits the reaction [Cyclophosphamide results in increased expression of RELA protein]; parthenolide inhibits the reaction [Cyclophosphamide results in increased expression of RELA protein modified form]; Plant Extracts inhibits the reaction [Cyclophosphamide results in increased activity of RELA protein]; sacubitril-valsartan inhibits the reaction [Cyclophosphamide results in increased phosphorylation of RELA protein]; Valsartan inhibits the reaction [Cyclophosphamide results in increased phosphorylation of RELA protein]
CTD PMID:19303104, PMID:20433640, PMID:22099998, PMID:25451569, PMID:30506662, PMID:32197949 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Rev1 REV1, DNA directed polymerase decreases response to substance ISO REV1 protein results in decreased susceptibility to Cyclophosphamide CTD PMID:21068378 NCBI chr 9:44,714,137...44,786,330
Ensembl chr 9:44,714,386...44,786,041
JBrowse link
G RGD1564243 similar to brain Zn-finger protein increases expression EXP Cyclophosphamide results in increased expression of RGD1564243 mRNA CTD PMID:27281708 NCBI chr17:45,745,442...45,746,753 JBrowse link
G RGD1565844 similar to RIKEN cDNA 1700045I19 increases expression EXP Cyclophosphamide results in increased expression of RGD1565844 mRNA CTD PMID:27281708 NCBI chr  X:32,495,573...32,496,646
Ensembl chr  X:32,495,809...32,496,549
JBrowse link
G Ring1 ring finger protein 1 decreases expression EXP Cyclophosphamide results in decreased expression of RING1 mRNA CTD PMID:27281708 NCBI chr20:3,812,287...3,815,834
Ensembl chr20:3,812,287...3,815,834
JBrowse link
G Ripply3 ripply transcriptional repressor 3 increases expression ISO Cyclophosphamide results in increased expression of RIPPLY3 mRNA CTD PMID:21527772 NCBI chr11:34,557,679...34,565,776
Ensembl chr11:34,557,679...34,565,776
JBrowse link
G Rnase2 ribonuclease A family member 2 decreases expression ISO Cyclophosphamide results in decreased expression of RNASE2 mRNA CTD PMID:17403535 NCBI chr15:28,154,482...28,155,291
Ensembl chr15:28,154,482...28,155,291
JBrowse link
G Rnd1 Rho family GTPase 1 increases expression EXP Cyclophosphamide results in increased expression of RND1 mRNA CTD PMID:23558518 NCBI chr 7:140,349,138...140,356,209
Ensembl chr 7:140,349,138...140,356,209
JBrowse link
G Rnf180 ring finger protein 180 increases expression EXP Cyclophosphamide results in increased expression of RNF180 mRNA CTD PMID:27281708 NCBI chr 2:35,718,100...35,892,578
Ensembl chr 2:35,718,889...35,870,578
JBrowse link
G Rnf216 ring finger protein 216 decreases expression EXP Cyclophosphamide results in decreased expression of RNF216 mRNA CTD PMID:27281708 NCBI chr12:13,508,429...13,631,689
Ensembl chr12:13,508,429...13,632,304
JBrowse link
G Rnf44 ring finger protein 44 increases expression EXP Cyclophosphamide results in increased expression of RNF44 mRNA CTD PMID:27281708 NCBI chr17:10,458,036...10,472,410
Ensembl chr17:10,458,110...10,472,447
JBrowse link
G Rnf5 ring finger protein 5 increases expression EXP Cyclophosphamide results in increased expression of RNF5 mRNA CTD PMID:27281708 NCBI chr20:4,366,244...4,368,690
Ensembl chr20:4,366,246...4,368,693
JBrowse link
G Rorc RAR-related orphan receptor C decreases expression
multiple interactions
ISO Cyclophosphamide results in decreased expression of RORC protein
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of RORC protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of RORC protein]
CTD PMID:32151603 NCBI chr 2:195,612,471...195,636,797
Ensembl chr 2:195,617,021...195,637,630
JBrowse link
G Rpa1 replication protein A1 decreases expression EXP Cyclophosphamide results in decreased expression of RPA1 mRNA CTD PMID:11906922 NCBI chr10:62,140,419...62,191,518
Ensembl chr10:62,140,419...62,191,512
JBrowse link
G Rpa2 replication protein A2 decreases expression EXP Cyclophosphamide results in decreased expression of RPA2 mRNA CTD PMID:11906922 NCBI chr 5:150,957,041...150,967,597
Ensembl chr 5:150,957,001...150,968,269
JBrowse link
G Rps3 ribosomal protein S3 decreases expression EXP Cyclophosphamide results in decreased expression of RPS3 mRNA CTD PMID:11906922 NCBI chr 1:164,435,868...164,441,167
Ensembl chr 1:164,435,878...164,441,167
JBrowse link
G Rps6ka2 ribosomal protein S6 kinase A2 affects response to substance ISO RPS6KA2 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 1:53,219,346...53,499,445
Ensembl chr 1:53,360,157...53,499,445
JBrowse link
G Rraga Ras-related GTP binding A decreases expression ISO Cyclophosphamide results in decreased expression of RRAGA mRNA CTD PMID:17403535 NCBI chr 5:104,941,067...104,942,662
Ensembl chr 5:104,941,066...104,942,662
JBrowse link
G Rras2 RAS related 2 increases expression ISO Cyclophosphamide results in increased expression of RRAS2 mRNA CTD PMID:17403535 NCBI chr 1:178,940,515...179,010,257
Ensembl chr 1:178,940,516...179,010,257
JBrowse link
G Rrm1 ribonucleotide reductase catalytic subunit M1 decreases expression ISO Cyclophosphamide results in decreased expression of RRM1 mRNA CTD PMID:21041162 NCBI chr 1:167,538,387...167,562,688
Ensembl chr 1:167,538,263...167,562,688
JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 multiple interactions ISO RRM2 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 6:43,884,627...43,890,818
Ensembl chr 6:43,884,678...43,889,515
JBrowse link
G Rrm2b ribonucleotide reductase regulatory TP53 inducible subunit M2B increases expression ISO Cyclophosphamide metabolite results in increased expression of RRM2B mRNA CTD PMID:21704725 NCBI chr 7:76,750,045...76,780,817
Ensembl chr 7:76,750,050...76,780,817
JBrowse link
G RT1-CE5 RT1 class I, locus CE5 increases expression ISO Cyclophosphamide results in increased expression of HLA-F mRNA CTD PMID:20849824 NCBI chr20:4,892,702...4,896,993
Ensembl chr20:4,892,702...4,896,991
JBrowse link
G Rtel1 regulator of telomere elongation helicase 1 increases expression ISO Cyclophosphamide results in increased expression of RTEL1 protein CTD PMID:17475930 NCBI chr 3:176,818,012...176,856,531
Ensembl chr 3:176,818,437...176,856,531
JBrowse link
G Runx3 RUNX family transcription factor 3 decreases expression ISO Cyclophosphamide results in decreased expression of RUNX3 mRNA CTD PMID:20849824 NCBI chr 5:153,507,093...153,531,137
Ensembl chr 5:153,507,093...153,531,137
JBrowse link
G Sall1 spalt-like transcription factor 1 affects response to substance ISO SALL1 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr19:23,387,737...23,405,025
Ensembl chr19:23,389,375...23,405,039
JBrowse link
G Satb1 SATB homeobox 1 decreases expression ISO Cyclophosphamide results in decreased expression of SATB1 mRNA CTD PMID:21041162 NCBI chr 9:2,181,135...2,277,949
Ensembl chr 9:2,190,915...2,274,629
JBrowse link
G Scg3 secretogranin III decreases expression ISO Cyclophosphamide results in decreased expression of SCG3 mRNA CTD PMID:15331540 NCBI chr 8:82,582,352...82,641,536
Ensembl chr 8:82,582,352...82,641,536
JBrowse link
G Scrt1 scratch family transcriptional repressor 1 increases expression EXP Cyclophosphamide results in increased expression of SCRT1 mRNA CTD PMID:27281708 NCBI chr 7:117,583,453...117,587,103
Ensembl chr 7:117,583,453...117,587,103
JBrowse link
G Scube2 signal peptide, CUB domain and EGF like domain containing 2 multiple interactions ISO SCUBE2 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 1:174,428,056...174,495,356
Ensembl chr 1:174,428,699...174,495,258
JBrowse link
G Sec23a Sec23 homolog A, COPII coat complex component decreases expression EXP Cyclophosphamide results in decreased expression of SEC23A mRNA CTD PMID:27281708 NCBI chr 6:80,059,742...80,107,340
Ensembl chr 6:80,060,916...80,107,236
JBrowse link
G Serpine1 serpin family E member 1 increases expression EXP Cyclophosphamide results in increased expression of SERPINE1 mRNA CTD PMID:23558518 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Sesn2 sestrin 2 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of SESN2 mRNA CTD PMID:24356939 NCBI chr 5:150,684,891...150,703,846
Ensembl chr 5:150,684,133...150,704,117
JBrowse link
G Sfn stratifin increases expression ISO Cyclophosphamide results in increased expression of SFN mRNA CTD PMID:21527772 NCBI chr 5:151,823,422...151,824,937
Ensembl chr 5:151,823,887...151,824,633
JBrowse link
G Sgce sarcoglycan, epsilon affects response to substance ISO SGCE protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr 4:29,726,140...29,769,902
Ensembl chr 4:29,726,146...29,778,039
JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of SGK1 mRNA CTD PMID:24356939 NCBI chr 1:24,185,451...24,302,309
Ensembl chr 1:24,185,435...24,302,298
JBrowse link
G Sharpin SHANK-associated RH domain interactor decreases expression EXP Cyclophosphamide results in decreased expression of SHARPIN mRNA CTD PMID:27281708 NCBI chr 7:117,413,151...117,417,455
Ensembl chr 7:117,413,152...117,417,363
JBrowse link
G Sirt5 sirtuin 5 increases expression EXP Cyclophosphamide results in increased expression of SIRT5 mRNA CTD PMID:27281708 NCBI chr17:23,986,710...24,013,854
Ensembl chr17:23,986,758...24,013,881
JBrowse link
G Sit1 signaling threshold regulating transmembrane adaptor 1 decreases expression ISO Cyclophosphamide results in decreased expression of SIT1 mRNA CTD PMID:21041162 NCBI chr 5:58,985,912...58,987,538
Ensembl chr 5:58,985,829...58,987,760
JBrowse link
G Slc22a5 solute carrier family 22 member 5 multiple interactions
decreases expression
EXP Carnitine inhibits the reaction [Cyclophosphamide results in decreased expression of SLC22A5 mRNA]; Carnitine inhibits the reaction [Cyclophosphamide results in decreased expression of SLC22A5 protein]
Cyclophosphamide results in decreased expression of SLC22A5 mRNA; Cyclophosphamide results in decreased expression of SLC22A5 protein
CTD PMID:22701146 NCBI chr10:39,201,101...39,228,090
Ensembl chr10:39,201,107...39,323,853
JBrowse link
G Slc2a2 solute carrier family 2 member 2 decreases expression ISO Cyclophosphamide results in decreased expression of SLC2A2 mRNA CTD PMID:15331540 NCBI chr 2:114,413,427...114,445,418
Ensembl chr 2:114,413,410...114,445,395
JBrowse link
G Slc2a6 solute carrier family 2 member 6 increases expression ISO Cyclophosphamide results in increased expression of SLC2A6 mRNA CTD PMID:21527772 NCBI chr 3:5,567,729...5,575,144
Ensembl chr 3:5,568,321...5,575,136
JBrowse link
G Slc39a13 solute carrier family 39 member 13 increases expression EXP Cyclophosphamide results in increased expression of SLC39A13 mRNA CTD PMID:27281708 NCBI chr 3:79,884,524...79,892,664
Ensembl chr 3:79,884,524...79,892,429
JBrowse link
G Slc39a14 solute carrier family 39 member 14 increases expression EXP Cyclophosphamide results in increased expression of SLC39A14 mRNA CTD PMID:27281708 NCBI chr15:51,982,872...52,029,841
Ensembl chr15:51,982,982...52,029,816
JBrowse link
G Slc39a5 solute carrier family 39 member 5 increases expression EXP Cyclophosphamide results in increased expression of SLC39A5 mRNA; Cyclophosphamide results in increased expression of SLC39A5 protein CTD PMID:27281708 NCBI chr 7:2,813,875...2,819,917
Ensembl chr 7:2,813,875...2,819,299
JBrowse link
G Slc39a6 solute carrier family 39 member 6 increases expression EXP Cyclophosphamide results in increased expression of SLC39A6 mRNA CTD PMID:27281708 NCBI chr18:16,523,450...16,543,992
Ensembl chr18:16,522,982...16,543,992
JBrowse link
G Slc3a2 solute carrier family 3 member 2 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of SLC3A2 mRNA CTD PMID:24356939 NCBI chr 1:224,906,566...224,921,029
Ensembl chr 1:224,906,554...224,921,092
JBrowse link
G Slc43a1 solute carrier family 43 member 1 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of SLC43A1 mRNA CTD PMID:24356939 NCBI chr 3:72,238,796...72,265,023
Ensembl chr 3:72,238,981...72,264,466
JBrowse link
G Slc7a11 solute carrier family 7 member 11 affects expression
decreases expression
ISO Cyclophosphamide affects the expression of SLC7A11 mRNA
Cyclophosphamide metabolite results in decreased expression of SLC7A11 mRNA
CTD PMID:23824090, PMID:24356939 NCBI chr 2:139,453,774...139,528,479
Ensembl chr 2:139,453,774...139,528,162
JBrowse link
G Slfn4 schlafen family member 4 increases expression ISO Cyclophosphamide results in increased expression of SLFN4 mRNA CTD PMID:15331540 NCBI chr10:70,411,686...70,435,162
Ensembl chr10:70,411,738...70,435,156
JBrowse link
G Slit1 slit guidance ligand 1 decreases expression ISO Cyclophosphamide results in decreased expression of SLIT1 mRNA CTD PMID:20849824 NCBI chr 1:260,843,481...260,992,366
Ensembl chr 1:260,843,483...260,992,366
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor decreases expression ISO Cyclophosphamide results in decreased expression of SLPI mRNA CTD PMID:15331540 NCBI chr 3:160,799,979...160,802,228
Ensembl chr 3:160,799,981...160,802,433
JBrowse link
G Snx10 sorting nexin 10 increases expression ISO Cyclophosphamide results in increased expression of SNX10 mRNA CTD PMID:15331540 NCBI chr 4:81,311,490...81,375,248
Ensembl chr 4:81,311,490...81,374,158
JBrowse link
G Soat1 sterol O-acyltransferase 1 affects response to substance ISO SOAT1 protein affects the susceptibility to Cyclophosphamide CTD PMID:16217747 NCBI chr13:74,035,258...74,077,759
Ensembl chr13:74,035,080...74,077,783
JBrowse link
G Socs1 suppressor of cytokine signaling 1 decreases expression ISO Cyclophosphamide results in decreased expression of SOCS1 mRNA CTD PMID:21041162 NCBI chr10:4,956,795...4,958,472
Ensembl chr10:4,957,326...4,958,461
JBrowse link
G Socs7 suppressor of cytokine signaling 7 increases expression EXP Cyclophosphamide results in increased expression of SOCS7 mRNA CTD PMID:11599041 NCBI chr10:85,301,797...85,337,971
Ensembl chr10:85,301,875...85,330,397
JBrowse link
G Sod1 superoxide dismutase 1 decreases expression
multiple interactions
ISO Cyclophosphamide results in decreased expression of SOD1 mRNA
[Doxorubicin co-treated with Cyclophosphamide] results in increased expression of SOD1 protein; Plant Extracts inhibits the reaction [Cyclophosphamide results in decreased expression of SOD1 mRNA]
CTD PMID:23542512, PMID:29228376 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 increases expression
affects response to substance
decreases expression
ISO
EXP
Cyclophosphamide results in increased expression of SOD2 mRNA
SOD2 polymorphism affects the susceptibility to Cyclophosphamide
Cyclophosphamide results in decreased expression of SOD2 mRNA
CTD PMID:11599041, PMID:11906922, PMID:15331540, PMID:20309628 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sord sorbitol dehydrogenase decreases activity
multiple interactions
EXP Cyclophosphamide results in decreased activity of SORD protein
Plant Extracts inhibits the reaction [Cyclophosphamide results in decreased activity of SORD protein]
CTD PMID:25446862 NCBI chr 3:114,176,127...114,207,368
Ensembl chr 3:114,176,309...114,207,366
JBrowse link
G Sp2 Sp2 transcription factor decreases expression EXP Cyclophosphamide results in decreased expression of SP2 mRNA CTD PMID:27281708 NCBI chr10:84,890,930...84,920,886
Ensembl chr10:84,890,932...84,920,886
JBrowse link
G Sparc secreted protein acidic and cysteine rich decreases expression
increases expression
ISO Cyclophosphamide results in decreased expression of SPARC mRNA
Cyclophosphamide results in increased expression of SPARC mRNA
CTD PMID:15331540, PMID:17403535 NCBI chr10:40,742,390...40,764,232
Ensembl chr10:40,742,400...40,764,185
JBrowse link
G Spp1 secreted phosphoprotein 1 affects response to substance
increases expression
affects expression
ISO
EXP
SPP1 protein affects the susceptibility to Cyclophosphamide
Cyclophosphamide results in increased expression of SPP1 mRNA
Cyclophosphamide affects the expression of SPP1 mRNA
CTD PMID:16217747, PMID:20623750, PMID:23558518 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Srek1ip1 SREK1-interacting protein 1 increases expression EXP Cyclophosphamide results in increased expression of SREK1IP1 mRNA CTD PMID:27281708 NCBI chr 2:34,923,187...34,940,410 JBrowse link
G Srm spermidine synthase multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] affects the expression of SRM mRNA CTD PMID:16322899 NCBI chr 5:165,405,168...165,408,325
Ensembl chr 5:165,405,168...165,408,320
JBrowse link
G Ssrp1 structure specific recognition protein 1 increases expression EXP Cyclophosphamide results in increased expression of SSRP1 mRNA CTD PMID:11599041 NCBI chr 3:72,447,516...72,457,621
Ensembl chr 3:72,447,537...72,457,649
JBrowse link
G St13 ST13, Hsp70 interacting protein increases expression EXP Cyclophosphamide results in increased expression of ST13 mRNA CTD PMID:11599041 NCBI chr 7:122,585,770...122,635,731
Ensembl chr 7:122,585,771...122,635,731
JBrowse link
G St14 ST14 transmembrane serine protease matriptase multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] affects the expression of ST14 mRNA CTD PMID:16322899 NCBI chr 8:32,240,113...32,280,813
Ensembl chr 8:32,240,133...32,280,869
JBrowse link
G Stat1 signal transducer and activator of transcription 1 increases expression ISO Cyclophosphamide results in increased expression of STAT1 mRNA CTD PMID:21041162 NCBI chr 9:54,287,540...54,327,958
Ensembl chr 9:54,287,541...54,484,533
JBrowse link
G Stat3 signal transducer and activator of transcription 3 increases phosphorylation
decreases phosphorylation
EXP
ISO
Cyclophosphamide results in increased phosphorylation of STAT3 protein
Cyclophosphamide results in decreased phosphorylation of STAT3 protein
CTD PMID:19625377, PMID:21880982 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Stat5b signal transducer and activator of transcription 5B decreases expression ISO Cyclophosphamide results in decreased expression of STAT5B mRNA CTD PMID:21041162 NCBI chr10:88,686,207...88,712,313
Ensembl chr10:88,686,207...88,754,829
JBrowse link
G Stip1 stress-induced phosphoprotein 1 decreases expression ISO
EXP
Cyclophosphamide results in decreased expression of STIP1 mRNA CTD PMID:11906922, PMID:15331540 NCBI chr 1:222,274,133...222,293,139
Ensembl chr 1:222,274,133...222,293,148
JBrowse link
G Stk39 serine threonine kinase 39 multiple interactions ISO [Doxorubicin co-treated with Cyclophosphamide] affects the expression of STK39 mRNA CTD PMID:16322899 NCBI chr 3:54,359,449...54,625,702
Ensembl chr 3:54,359,451...54,625,414
JBrowse link
G Stk4 serine/threonine kinase 4 decreases expression ISO Cyclophosphamide results in decreased expression of STK4 mRNA CTD PMID:21041162 NCBI chr 3:160,467,552...160,546,540
Ensembl chr 3:160,467,552...160,546,540
JBrowse link
G Stmn3 stathmin 3 increases expression ISO Cyclophosphamide results in increased expression of STMN3 mRNA CTD PMID:21527772 NCBI chr 3:176,808,016...176,816,108
Ensembl chr 3:176,808,017...176,816,162
JBrowse link
G Stom stomatin increases expression ISO Cyclophosphamide results in increased expression of STOM mRNA CTD PMID:21527772 NCBI chr 3:14,515,576...14,538,199
Ensembl chr 3:14,514,868...14,538,241
JBrowse link
G Sun1 Sad1 and UNC84 domain containing 1 decreases expression EXP Cyclophosphamide results in decreased expression of SUN1 mRNA CTD PMID:27281708 NCBI chr12:17,488,482...17,533,334
Ensembl chr12:17,488,487...17,522,534
JBrowse link
G Tac1 tachykinin, precursor 1 multiple interactions
increases expression
increases secretion
affects expression
EXP
ISO
Botulinum Toxins, Type A inhibits the reaction [Cyclophosphamide results in increased secretion of TAC1 protein]
Cyclophosphamide results in increased expression of TAC1 protein
Cyclophosphamide affects the expression of TAC1 mRNA
CTD PMID:11312054, PMID:18184328, PMID:18563302, PMID:22842586 NCBI chr 4:33,638,853...33,646,819
Ensembl chr 4:33,638,709...33,646,819
JBrowse link
G Tacr1 tachykinin receptor 1 multiple interactions
increases expression
decreases response to substance
ISO
EXP
[alpha-amyrin co-treated with beta-amyrin] inhibits the reaction [Cyclophosphamide results in increased expression of TACR1 protein]
GR 82334 inhibits the reaction [Cyclophosphamide results in increased expression of TACR1 protein]; Suramin inhibits the reaction [Cyclophosphamide results in increased expression of TACR1 protein]
TACR1 gene mutant form results in decreased susceptibility to Cyclophosphamide
CTD PMID:10854767, PMID:18210232, PMID:23666265 NCBI chr 4:113,247,236...113,416,139
Ensembl chr 4:113,247,795...113,414,504
JBrowse link
G Tafa5 TAFA chemokine like family member 5 increases expression ISO Cyclophosphamide results in increased expression of TAFA5 mRNA CTD PMID:21621594 NCBI chr 7:128,500,009...128,728,834
Ensembl chr 7:128,500,011...128,728,928
JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member increases expression ISO Cyclophosphamide results in increased expression of TAP1 mRNA CTD PMID:21527772 NCBI chr20:3,979,302...3,989,669
Ensembl chr20:3,979,035...3,989,669
JBrowse link
G Tat tyrosine aminotransferase affects expression
decreases expression
EXP Cyclophosphamide affects the expression of TAT mRNA
Cyclophosphamide results in decreased expression of TAT mRNA
CTD PMID:18246545 NCBI chr19:41,675,639...41,686,195
Ensembl chr19:41,675,355...41,686,229
JBrowse link
G Tbx21 T-box transcription factor 21 multiple interactions
decreases expression
ISO Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of TBX21 protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of TBX21 protein] CTD PMID:32151603 NCBI chr10:85,032,799...85,049,331
Ensembl chr10:85,032,799...85,049,331
JBrowse link
G Tcf7 transcription factor 7 decreases expression ISO Cyclophosphamide results in decreased expression of TCF7 mRNA CTD PMID:21041162 NCBI chr10:37,616,033...37,646,027
Ensembl chr10:37,617,279...37,645,802
JBrowse link
G Tcp1 t-complex 1 decreases expression
increases expression
EXP Cyclophosphamide results in decreased expression of TCP1 mRNA
Cyclophosphamide results in increased expression of TCP1 mRNA
CTD PMID:11599041, PMID:11906922 NCBI chr 1:48,025,664...48,033,343
Ensembl chr 1:48,025,663...48,033,396
JBrowse link
G Tex30 testis expressed 30 decreases expression ISO Cyclophosphamide results in decreased expression of TEX30 mRNA CTD PMID:17403535 NCBI chr 9:50,858,737...50,868,238
Ensembl chr 9:50,858,737...50,868,238
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression
increases secretion
multiple interactions
affects expression
ISO
EXP
Cyclophosphamide results in increased expression of TGFB1 mRNA
Cyclophosphamide results in increased secretion of TGFB1 protein
Cyclophosphamide results in increased expression of and results in increased activity of TGFB1 protein
Cyclophosphamide affects the expression of TGFB1 mRNA
DCN protein inhibits the reaction [TGFB1 protein results in decreased susceptibility to [Cyclophosphamide co-treated with Cisplatin co-treated with Melphalan co-treated with Thiotepa]]; TGFB1 protein results in decreased susceptibility to [Cyclophosphamide co-treated with Cisplatin co-treated with Melphalan co-treated with Thiotepa]
CTD PMID:9509296, PMID:12624490, PMID:19691848, PMID:21068404 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tgfb2 transforming growth factor, beta 2 increases expression EXP Cyclophosphamide results in increased expression of TGFB2 mRNA CTD PMID:23558518 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
JBrowse link
G Tgfb3 transforming growth factor, beta 3 multiple interactions
decreases expression
ISO Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of TGFB3 protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of TGFB3 protein] CTD PMID:32151603 NCBI chr 6:109,913,757...109,936,217
Ensembl chr 6:109,913,757...109,935,533
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 increases expression ISO Cyclophosphamide results in increased expression of TGFBR2 mRNA CTD PMID:21041162 NCBI chr 8:124,310,288...124,399,345
Ensembl chr 8:124,312,754...124,399,494
JBrowse link
G Thbs1 thrombospondin 1 increases expression
multiple interactions
EXP
ISO
Cyclophosphamide results in increased expression of THBS1 protein
Cyclophosphamide results in increased expression of THBS1 mRNA
axitinib inhibits the reaction [Cyclophosphamide results in increased expression of THBS1 protein]
CTD PMID:15331540, PMID:18202011 NCBI chr 3:109,862,120...109,873,466
Ensembl chr 3:109,862,117...109,873,466
JBrowse link
G Thnsl2 threonine synthase-like 2 multiple interactions ISO THNSL2 mRNA affects the susceptibility to [Paclitaxel co-treated with Fluorouracil co-treated with Doxorubicin co-treated with Cyclophosphamide] CTD PMID:16896004 NCBI chr 4:98,976,559...98,997,187
Ensembl chr 4:98,976,550...98,995,590
JBrowse link
G Thy1 Thy-1 cell surface antigen decreases expression ISO Cyclophosphamide results in decreased expression of THY1 mRNA CTD PMID:21041162 NCBI chr 8:48,382,121...48,387,271
Ensembl chr 8:48,382,121...48,386,935
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression EXP Cyclophosphamide results in increased expression of TIMP1 mRNA CTD PMID:23558518 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Tjp1 tight junction protein 1 multiple interactions
decreases expression
EXP
ISO
Anthocyanins inhibits the reaction [Cyclophosphamide results in decreased expression of TJP1 protein]; Plant Extracts inhibits the reaction [Cyclophosphamide results in decreased expression of TJP1 protein]
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of TJP1 protein]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of TJP1 protein]
CTD PMID:25451569, PMID:32151603 NCBI chr 1:126,146,489...126,515,359
Ensembl chr 1:126,146,489...126,227,469
JBrowse link
G Tlr2 toll-like receptor 2 decreases expression
multiple interactions
ISO Cyclophosphamide results in decreased expression of TLR2 mRNA
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of TLR2 mRNA]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of TLR2 mRNA]
CTD PMID:32151603 NCBI chr 2:182,840,171...182,846,061
Ensembl chr 2:182,840,727...182,846,061
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions
decreases expression
ISO Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of TLR4 mRNA] CTD PMID:32151603 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tlr6 toll-like receptor 6 decreases expression
multiple interactions
ISO Cyclophosphamide results in decreased expression of TLR6 mRNA
Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of TLR6 mRNA]; Levamisole inhibits the reaction [Cyclophosphamide results in decreased expression of TLR6 mRNA]
CTD PMID:32151603 NCBI chr14:45,024,351...45,041,188
Ensembl chr14:45,024,351...45,046,446
JBrowse link
G Tlr9 toll-like receptor 9 multiple interactions
increases expression
ISO Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in increased expression of TLR9 protein] CTD PMID:29753871 NCBI chr 8:114,916,122...114,920,171
Ensembl chr 8:114,916,122...114,920,171
JBrowse link
G Tm4sf1 transmembrane 4 L six family member 1 increases expression ISO Cyclophosphamide results in increased expression of TM4SF1 mRNA CTD PMID:17403535 NCBI chr 2:147,382,866...147,392,062
Ensembl chr 2:147,382,866...147,392,062
JBrowse link
G Tm6sf1 transmembrane 6 superfamily member 1 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of TM6SF1 mRNA CTD PMID:24356939 NCBI chr 1:143,657,607...143,703,829
Ensembl chr 1:143,661,521...143,703,759
JBrowse link
G Tmed3 transmembrane p24 trafficking protein 3 decreases expression ISO Cyclophosphamide results in decreased expression of TMED3 mRNA CTD PMID:15331540 NCBI chr 8:97,075,194...97,083,107
Ensembl chr 8:97,075,160...97,083,120
JBrowse link
G Tmeff1 transmembrane protein with EGF-like and two follistatin-like domains 1 affects response to substance
decreases expression
ISO
EXP
TMEFF1 protein affects the susceptibility to Cyclophosphamide
Cyclophosphamide results in decreased expression of TMEFF1 mRNA
CTD PMID:16217747, PMID:27466211 NCBI chr 5:64,326,733...64,412,531
Ensembl chr 5:64,326,733...64,412,523
JBrowse link
G Tmem267 transmembrane protein 267 decreases expression ISO Cyclophosphamide metabolite results in decreased expression of TMEM267 mRNA CTD PMID:24356939 NCBI chr 2:52,356,449...52,366,075
Ensembl chr 2:52,358,097...52,366,667
JBrowse link
G Tnf tumor necrosis factor affects expression
decreases expression
multiple interactions
increases expression
decreases response to substance
increases response to substance
ISO
EXP
Cyclophosphamide affects the expression of TNF mRNA
Cyclophosphamide results in decreased expression of TNF mRNA
[Cyclophosphamide co-treated with Methotrexate co-treated with Fluorouracil] results in decreased expression of TNF protein; Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in decreased expression of TNF mRNA]; Fungal Polysaccharides inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]; ganoderic acid A inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]
Cyclophosphamide results in increased expression of TNF mRNA; Cyclophosphamide results in increased expression of TNF protein
Anthocyanins inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]; Curcumin inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]; Pentoxifylline inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]; Plant Extracts inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]; Rolipram inhibits the reaction [Cyclophosphamide results in increased expression of TNF mRNA]; Rutin inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]; Simvastatin inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]; thymoquinone inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]
Cyclophosphamide affects the expression of TNF protein
TNF protein results in decreased susceptibility to Cyclophosphamide
TNF protein results in increased susceptibility to Cyclophosphamide
CTD PMID:8634684, PMID:11948286, PMID:12797522, PMID:18206168, PMID:18710439, PMID:18848347, PMID:18957084, PMID:19413659, PMID:20126887, PMID:20623750, PMID:20957680, PMID:23695977, PMID:25451569, PMID:25753322, PMID:29753871, PMID:30506662, PMID:31651976, PMID:32151603 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfaip3 TNF alpha induced protein 3 increases expression ISO Cyclophosphamide results in increased expression of TNFAIP3 mRNA CTD PMID:21873647 NCBI chr 1:14,401,103...14,416,369
Ensembl chr 1:14,402,913...14,412,807
JBrowse link
G Tnfrsf14 TNF receptor superfamily member 14 increases expression ISO Cyclophosphamide results in increased expression of TNFRSF14 mRNA CTD PMID:21527772 NCBI chr 5:172,328,259...172,337,221
Ensembl chr 5:172,328,262...172,335,892
JBrowse link
G Tnfrsf18 TNF receptor superfamily member 18 decreases expression ISO Cyclophosphamide results in decreased expression of TNFRSF18 mRNA CTD PMID:15591121 NCBI chr 5:173,459,371...173,463,980
Ensembl chr 5:173,460,354...173,463,140
JBrowse link
G Tnfrsf19 TNF receptor superfamily member 19 increases expression
multiple interactions
ISO Cyclophosphamide results in increased expression of TNFRSF19 mRNA
5-(N-methyl-N-propargylaminomethyl)-8-hydroxyquinoline inhibits the reaction [Cyclophosphamide results in increased expression of TNFRSF19 mRNA]
CTD PMID:30760223 NCBI chr15:41,249,820...41,316,203
Ensembl chr15:41,246,308...41,338,284
JBrowse link
G Tnfsf9 TNF superfamily member 9 increases expression ISO Cyclophosphamide results in increased expression of TNFSF9 mRNA CTD PMID:21527772 NCBI chr 9:9,909,942...9,912,276
Ensembl chr 9:9,909,948...9,912,276
JBrowse link
G Tnni3 troponin I3, cardiac type increases expression ISO Cyclophosphamide results in increased expression of TNNI3 protein CTD PMID:17562616, PMID:18548196 NCBI chr 1:72,882,806...72,886,490
Ensembl chr 1:72,882,806...72,886,488