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ONTOLOGY REPORT - ANNOTATIONS


Term:cytisine
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Accession:CHEBI:4055 term browser browse the term
Definition:An organic heterotricyclic compound that is the toxic principle in Laburnum seeds and is found in many members of the Fabaceae (legume, pea or bean) family. An acetylcholine agonist, it is widely used throughout Eastern Europe as an aid to giving up smoking.
Synonyms:exact_synonym: (1R,5S)-1,2,3,4,5,6-hexahydro-8H-1,5-methanopyrido[1,2-a][1,5]diazocin-8-one
 related_synonym: Formula=C11H14N2O;   InChI=1S/C11H14N2O/c14-11-3-1-2-10-9-4-8(5-12-6-9)7-13(10)11/h1-3,8-9,12H,4-7H2/t8-,9+/m0/s1;   InChIKey=ANJTVLIZGCUXLD-DTWKUNHWSA-N;   SMILES=O=c1cccc2[C@H]3CNC[C@H](C3)Cn12;   baptitoxin;   baptitoxine;   laburnin;   sophorin;   sophorine
 xref: CAS:485-35-8 "ChemIDplus";   CAS:485-35-8 "KEGG COMPOUND";   CAS:485-35-8 "NIST Chemistry WebBook";   KEGG:C10763;   KEGG:D07770;   KNApSAcK:C00002218;   LINCS:LSM-25650
 xref_mesh: MESH:C004712
 xref: PDBeChem:C5E;   PMID:21217866 "Europe PMC";   PMID:21991893 "Europe PMC";   PMID:22090039 "Europe PMC";   PMID:22250168 "Europe PMC";   PMID:22367109 "Europe PMC";   PMID:23022271 "Europe PMC";   PMID:23404838 "Europe PMC";   PMID:23563038 "Europe PMC";   PMID:23601929 "Europe PMC";   PMID:23876236 "Europe PMC";   PMID:23966067 "Europe PMC";   PMID:23974638 "Europe PMC";   PMID:24117010 "Europe PMC";   PMID:24550234 "Europe PMC";   PMID:24831822 "Europe PMC";   PMID:24885253 "Europe PMC";   PMID:25117409 "Europe PMC";   PMID:25231024 "Europe PMC";   PMID:25288485 "Europe PMC";   PMID:25517706 "Europe PMC";   PMID:25517710 "Europe PMC";   Reaxys:83882 "Reaxys";   Wikipedia:Cytisine


show annotations for term's descendants       view all columns           Sort by:
 
cytisine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Chrna2 cholinergic receptor nicotinic alpha 2 subunit JBrowse link 15 42,808,897 42,825,179 RGD:6480464
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit JBrowse link 8 59,594,007 59,607,122 RGD:6480464
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit JBrowse link 3 176,533,182 176,547,965 RGD:6480464
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit JBrowse link 1 123,897,341 124,039,263 RGD:6480464
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit JBrowse link 2 189,088,570 189,096,785 RGD:6480464
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit JBrowse link 8 59,610,489 59,629,073 RGD:6480464
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:6480464
G Tbx21 T-box transcription factor 21 JBrowse link 10 85,032,799 85,049,331 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19716
    role 19663
      biological role 19661
        biochemical role 19179
          metabolite 19151
            alkaloid 5274
              cytisine 9
Path 2
Term Annotations click to browse term
  CHEBI ontology 19716
    subatomic particle 19712
      composite particle 19712
        hadron 19712
          baryon 19712
            nucleon 19712
              atomic nucleus 19712
                atom 19712
                  main group element atom 19598
                    p-block element atom 19598
                      carbon group element atom 19486
                        carbon atom 19480
                          organic molecular entity 19480
                            organic group 18407
                              organic divalent group 18397
                                organodiyl group 18397
                                  carbonyl group 18285
                                    carbonyl compound 18285
                                      carboxylic acid 17940
                                        carboacyl group 16948
                                          univalent carboacyl group 16948
                                            carbamoyl group 16630
                                              carboxamide 16630
                                                lactam 2976
                                                  cytisine 9
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