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ONTOLOGY REPORT - ANNOTATIONS


Term:flufenamic acid
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Accession:CHEBI:42638 term browser browse the term
Definition:An aromatic amino acid consisting of anthranilic acid carrying an N-(trifluoromethyl)phenyl substituent. An analgesic and anti-inflammatory, it is used in rheumatic disorders.
Synonyms:related_synonym: 2-[3-(trifluoromethyl)anilino]benzoic acid;   2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid;   3'-trifluoromethyldiphenylamine-2-carboxylic acid;   Achless;   FFA;   Flufenaminsaeure;   Formula=C14H10F3NO2;   InChI=1S/C14H10F3NO2/c15-14(16,17)9-4-3-5-10(8-9)18-12-7-2-1-6-11(12)13(19)20/h1-8,18H,(H,19,20);   InChIKey=LPEPZBJOKDYZAD-UHFFFAOYSA-N;   N-(3-trifluoromethylphenyl)anthranilic acid;   N-(alpha,alpha,alpha-trifluoro-m-tolyl)anthranilic acid;   SMILES=OC(=O)c1ccccc1Nc1cccc(c1)C(F)(F)F;   acide flufenamique;   acido flufenamico;   acidum flufenamicum;   fluphenamic acid
 alt_id: CHEBI:31619;   CHEBI:42631
 xref: Beilstein:1996069 "ChemIDplus";   CAS:530-78-9 "ChemIDplus";   CAS:530-78-9 "KEGG COMPOUND";   CAS:530-78-9 "NIST Chemistry WebBook";   DrugBank:DB02266;   Drug_Central:1193 "DrugCentral";   Gmelin:1327188 "Gmelin";   KEGG:C13038;   KEGG:D01581;   LINCS:LSM-2973
 xref_mesh: MESH:D005439
 xref: PDBeChem:FLF;   PMID:11093589 "Europe PMC";   PMID:15275834 "Europe PMC";   PMID:18436631 "Europe PMC";   PMID:20589945 "Europe PMC";   PMID:28166217 "Europe PMC";   Reaxys:1996069 "Reaxys";   Wikipedia:Flufenamic_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:520819


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flufenamic acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adam17 ADAM metallopeptidase domain 17 JBrowse link 6 43,400,525 43,448,280 RGD:6480464
G Akr1c1 aldo-keto reductase family 1, member C1 JBrowse link 17 69,441,253 69,460,334 RGD:6480464
G Akr1c2 aldo-keto reductase family 1, member C2 JBrowse link 17 69,388,337 69,435,160 RGD:6480464
G Akr1c3 aldo-keto reductase family 1, member C3 JBrowse link 17 69,761,126 69,778,021 RGD:6480464
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:6480464
G Asic5 acid sensing ion channel subunit family member 5 JBrowse link 2 180,935,392 180,964,365 RGD:6480464
G Bad BCL2-associated agonist of cell death JBrowse link 1 222,198,516 222,207,459 RGD:6480464
G Bak1 BCL2-antagonist/killer 1 JBrowse link 20 5,609,620 5,618,899 RGD:6480464
G Best1 bestrophin 1 JBrowse link 1 226,033,146 226,049,893 RGD:6480464
G Bid BH3 interacting domain death agonist JBrowse link 4 153,439,812 153,465,247 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Casr calcium-sensing receptor JBrowse link 11 67,188,204 67,262,261 RGD:6480464
G Cftr CF transmembrane conductance regulator JBrowse link 4 42,693,263 42,860,679 RGD:6480464
G Cga glycoprotein hormones, alpha polypeptide JBrowse link 5 50,362,491 50,393,368 RGD:6480464
G Chrm1 cholinergic receptor, muscarinic 1 JBrowse link 1 224,869,087 224,885,101 RGD:6480464
G Dhrs11 dehydrogenase/reductase 11 JBrowse link 10 72,144,042 72,153,496 RGD:6480464
G Fshb follicle stimulating hormone subunit beta JBrowse link 3 98,088,321 98,092,131 RGD:6480464
G Grm1 glutamate metabotropic receptor 1 JBrowse link 1 4,753,141 5,165,859 RGD:6480464
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:6480464
G Il1a interleukin 1 alpha JBrowse link 3 121,824,712 121,836,122 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:6480464
G Kcnk10 potassium two pore domain channel subfamily K member 10 JBrowse link 6 122,417,079 122,549,532 RGD:6480464
G Kcnk2 potassium two pore domain channel subfamily K member 2 JBrowse link 13 107,690,111 107,886,476 RGD:6480464
G Kcnk4 potassium two pore domain channel subfamily K member 4 JBrowse link 1 222,182,997 222,192,139 RGD:6480464
G Kiss1 KiSS-1 metastasis-suppressor JBrowse link 13 50,529,506 50,537,603 RGD:6480464
G Kiss1r KISS1 receptor JBrowse link 7 12,606,210 12,609,868 RGD:6480464
G Ldlr low density lipoprotein receptor JBrowse link 8 22,750,425 22,773,305 RGD:6480464
G Lep leptin JBrowse link 4 56,337,695 56,351,818 RGD:6480464
G Lhb luteinizing hormone subunit beta JBrowse link 1 101,409,992 101,413,725 RGD:6480464
G Nkx3-1 NK3 homeobox 1 JBrowse link 15 51,065,316 51,067,908 RGD:6480464
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:6480464
G Panx1 Pannexin 1 JBrowse link 8 13,567,185 13,606,040 RGD:6480464
G Ppara peroxisome proliferator activated receptor alpha JBrowse link 7 126,618,872 126,687,282 RGD:6480464
G Pparg peroxisome proliferator-activated receptor gamma JBrowse link 4 147,274,055 147,399,383 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:6480464
G Sell selectin L JBrowse link 13 82,369,820 82,387,774 RGD:6480464
G Slc6a11 solute carrier family 6 member 11 JBrowse link 4 146,106,386 146,223,228 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Trpc6 transient receptor potential cation channel, subfamily C, member 6 JBrowse link 8 6,811,543 6,917,534 RGD:6480464
G Trpm2 transient receptor potential cation channel, subfamily M, member 2 JBrowse link 20 11,434,062 11,482,880 RGD:6480464
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 JBrowse link 1 101,293,300 101,323,484 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19741
    role 19688
      application 19339
        solvent 16079
          (trifluoromethyl)benzene 364
            flufenamic acid 42
Path 2
Term Annotations click to browse term
  CHEBI ontology 19741
    subatomic particle 19737
      composite particle 19737
        hadron 19737
          baryon 19737
            nucleon 19737
              atomic nucleus 19737
                atom 19737
                  main group element atom 19622
                    main group molecular entity 19622
                      s-block molecular entity 19388
                        hydrogen molecular entity 19377
                          hydrides 18283
                            organic hydride 17547
                              organic fundamental parent 17547
                                hydrocarbon 16958
                                  alkane 12514
                                    methane 9394
                                      halomethane 9394
                                        fluoromethanes 6265
                                          fluoroform 6265
                                            trifluoromethyl group 6265
                                              (trifluoromethyl)benzenes 6265
                                                (trifluoromethyl)benzene 364
                                                  flufenamic acid 42
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.