Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:dantrolene
go back to main search page
Accession:CHEBI:4317 term browser browse the term
Definition:The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin.
Synonyms:exact_synonym: 1-({[5-(4-nitrophenyl)furan-2-yl]methylidene}amino)imidazolidine-2,4-dione
 related_synonym: 1-((5-(p-nitrophenyl)furfurylidene)amino)hydantoin;   Formula=C14H10N4O5;   InChI=1S/C14H10N4O5/c19-13-8-17(14(20)16-13)15-7-11-5-6-12(23-11)9-1-3-10(4-2-9)18(21)22/h1-7H,8H2,(H,16,19,20);   InChIKey=OZOMQRBLCMDCEG-UHFFFAOYSA-N;   SMILES=[O-][N+](=O)c1ccc(cc1)-c1ccc(C=NN2CC(=O)NC2=O)o1;   dantroleno;   dantrolenum
 xref: Beilstein:705189 "Beilstein";   CAS:7261-97-4 "ChemIDplus";   CAS:7261-97-4 "KEGG COMPOUND";   DrugBank:DB01219;   KEGG:C06939;   KEGG:D02347;   LINCS:LSM-3823
 xref_mesh: MESH:D003620
 xref: Patent:NL6612588;   Patent:US3415821
 cyclic_relationship: is_conjugate_acid_of CHEBI:59697


show annotations for term's descendants       view all columns           Sort by:
 
dantrolene term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group) JBrowse link 6 58,584,491 58,692,451 RGD:6480464
G Atf4 activating transcription factor 4 JBrowse link 15 80,255,184 80,257,545 RGD:6480464
G Bcl2 B cell leukemia/lymphoma 2 JBrowse link 1 106,538,176 106,714,290 RGD:6480464
G Bdnf brain derived neurotrophic factor JBrowse link 2 109,674,700 109,727,043 RGD:6480464
G Capn1 calpain 1 JBrowse link 19 5,988,545 6,015,825 RGD:6480464
G Capn2 calpain 2 JBrowse link 1 182,467,253 182,517,610 RGD:6480464
G Capn3 calpain 3 JBrowse link 2 120,463,593 120,504,919 RGD:6480464
G Casp3 caspase 3 JBrowse link 8 46,617,291 46,639,698 RGD:6480464
G Casp9 caspase 9 JBrowse link 4 141,793,612 141,815,978 RGD:6480464
G Ccl2 chemokine (C-C motif) ligand 2 JBrowse link 11 82,035,577 82,037,452 RGD:6480464
G Ccl5 chemokine (C-C motif) ligand 5 JBrowse link 11 83,525,778 83,530,518 RGD:6480464
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 9 57,687,928 57,703,824 RGD:6480464
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 9 57,676,937 57,683,655 RGD:6480464
G Ddit3 DNA-damage inducible transcript 3 JBrowse link 10 127,290,793 127,296,291 RGD:6480464
G Edn1 endothelin 1 JBrowse link 13 42,301,476 42,307,990 RGD:6480464
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 JBrowse link 6 70,844,484 70,905,241 RGD:6480464
G Eif2s1 eukaryotic translation initiation factor 2, subunit 1 alpha JBrowse link 12 78,862,072 78,887,010 RGD:6480464
G Gfap glial fibrillary acidic protein JBrowse link 11 102,887,336 102,897,200 RGD:6480464
G Hspa5 heat shock protein 5 JBrowse link 2 34,772,090 34,776,529 RGD:6480464
G Ifng interferon gamma JBrowse link 10 118,441,046 118,445,894 RGD:6480464
G Igf1 insulin-like growth factor 1 JBrowse link 10 87,858,265 87,937,047 RGD:6480464
G Igf2 insulin-like growth factor 2 JBrowse link 7 142,650,768 142,666,816 RGD:6480464
G Il10 interleukin 10 JBrowse link 1 131,019,845 131,024,970 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 2 129,364,569 129,371,164 RGD:6480464
G Il6 interleukin 6 JBrowse link 5 30,013,114 30,019,975 RGD:6480464
G Kcnh2 potassium voltage-gated channel, subfamily H (eag-related), member 2 JBrowse link 5 24,319,589 24,351,684 RGD:6480464
G Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 JBrowse link 7 46,097,123 46,100,952 RGD:6480464
G Lep leptin JBrowse link 6 29,060,221 29,073,876 RGD:6480464
G Mef2a myocyte enhancer factor 2A JBrowse link 7 67,231,163 67,376,456 RGD:6480464
G Mef2c myocyte enhancer factor 2C JBrowse link 13 83,504,017 83,667,079 RGD:6480464
G Myh7 myosin, heavy polypeptide 7, cardiac muscle, beta JBrowse link 14 54,970,684 54,994,626 RGD:6480464
G Nefl neurofilament, light polypeptide JBrowse link 14 68,083,863 68,089,095 RGD:6480464
G Nefm neurofilament, medium polypeptide JBrowse link 14 68,119,545 68,125,004 RGD:6480464
G Nppa natriuretic peptide type A JBrowse link 4 148,000,722 148,002,074 RGD:6480464
G Nppb natriuretic peptide type B JBrowse link 4 147,985,786 147,987,205 RGD:6480464
G Ryr1 ryanodine receptor 1, skeletal muscle JBrowse link 7 29,003,340 29,125,179 RGD:6480464
G Ryr2 ryanodine receptor 2, cardiac JBrowse link 13 11,553,099 12,106,945 RGD:6480464
G Star steroidogenic acute regulatory protein JBrowse link 8 25,808,474 25,815,982 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 17 35,199,367 35,202,007 RGD:6480464
G Vim vimentin JBrowse link 2 13,574,311 13,582,826 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20971
    role 20952
      application 20373
        pharmaceutical 19971
          drug 19971
            neuromuscular agent 1262
              muscle relaxant 1257
                dantrolene 40
Path 2
Term Annotations click to browse term
  CHEBI ontology 20971
    subatomic particle 20965
      composite particle 20965
        hadron 20965
          baryon 20965
            nucleon 20965
              atomic nucleus 20965
                atom 20965
                  main group element atom 20803
                    p-block element atom 20803
                      carbon group element atom 20543
                        carbon atom 20519
                          organic molecular entity 20519
                            organic molecule 20371
                              organic cyclic compound 20047
                                organic heterocyclic compound 18970
                                  organic heteromonocyclic compound 16512
                                    diazolidine 567
                                      imidazolidines 558
                                        imidazolidinone 466
                                          imidazolidine-2,4-dione 444
                                            dantrolene 40
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.